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Fatores associados à osteoporose em pessoas idosas em um centro de referência
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Colares, Thomaz de Figueiredo Braga

; Vasconcelos, Ana Carolina Bromenschenkel

; Maia, Luciana Colares

; Caldeira, Antônio Prates

; Rossi-Barbosa, Luiza Augusta Rosa

PsychTech & Health Journal

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Dez 2023, Volume 7 Nº 2 Páginas 63 - 72

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract This study aimed to estimate the prevalence of osteoporosis among elderly individuals receiving treatment at a designated reference center and to identify associated factors. The research employed a cross-sectional, analytical design, involving the collection of data from medical records and interviews with elderly individuals undergoing treatment at the Reference Center for Health Care for the Elderly (CRASI), specifically those who underwent bone densitometry examinations in the years 2017 and 2018. Bivariate analysis was conducted to explore the association between osteoporosis and various group characteristics, including sociodemographic profile, Body Mass Index (BMI), lifestyle habits, care, and health conditions. Variables showing an association up to a significance level of 20% (p ≤ .20) were collectively evaluated through Poisson multiple regression with a robust estimator. Only variables demonstrating a significance level of up to 5% were admitted to the final model. The prevalence of osteoporosis was found to be 48.5%. In the final model, the following variables were identified as being associated: female sex (RP = 1.88; 95%CI: 1.36 - 2.60), age over 80 years old (RP = 1.55; 95%CI: 1.29 - 1.85), BMI less than 22 (RP = 1.23; 95%CI: 1.02 - 1.49), and as a protective factor, BMI above 27 (RP = .52; 95%CI: .41 - .67). In conclusion, a high prevalence of osteoporosis was observed, with associations identified between osteoporosis and modifiable factors such as low weight, as well as non-modifiable factors including sex and age. No significant associations were discerned with variables related to lifestyle habits.

Resumo Este estudo objetivou estimar a prevalência de osteoporose em idosos atendidos em um centro de referência e identificar fatores associados. Trata-se de um estudo transversal, analítico, com coleta de dados em prontuários médicos e entrevistas aos idosos atendidos no Centro de Referência em Assistência à Saúde dos Idosos (CRASI), e que realizaram exame de densitometria óssea nos anos de 2017 e 2018. Utilizou-se análise bivariada para investigar a associação entre osteoporose e características do grupo: perfil sociodemográfico, Índice de Massa Corporal (IMC), hábitos de vida, cuidados e condições de saúde. As variáveis com associação até o nível de 20% (p ≤ .20) foram avaliadas de forma conjunta por regressão múltipla de Poisson com estimador robusto, admitindo-se para o modelo final apenas as variáveis com nível de significância de até 5%. A prevalência de osteoporose foi de 48.5%. No modelo final ficaram associadas as variáveis: sexo feminino (RP = 1.88; IC95%: 1.36 - 2.60), idade acima de 80 anos (RP = 1.55; IC95%: 1.29 - 1.85), IMC menor que 22 (RP = 1.23; IC95%: 1.02 - 1.49) e como protetor IMC acima de 27 (RP = .52; IC95%: .41 - .67). Concluindo,verificou-se alta prevalência de osteoporose e associação como fator modificável o baixo peso e outros não modificáveis: sexo e idade. Não foram identificadas associações com variáveis relacionadas aos hábitos de vida.

https://doi.org/10.26580/pthj.art67-2024

Core curriculum in cariology for dentistry degrees in the Republic of Argentina
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Carletto-Kórber, Fabiana PM

; Sorazabal, Ana

; Medici, Silvia

; Ali, Sofía

; Barrionuevo, Alejandra

; Cardozo, Juana

; Cucchi, Analía

; D'Eramo, Luciana

; Escandriolo, Jorge

; Fontanetti, Pablo

; García, Shirley

; Lombardo, Adriana

; Mardenlli, Alejandra

; Masoli, Carla

; Mulbany, Patricia

; Pereira, Lía

; Pérez, Silvia

; Preliasco, Mariana

; Rossi, Glenda

; Squassi, Aldo

; Ulloque, Jorgelina

; Vaculik, Patricia

; Ventrera, Verónica

; Bordoni, Noemí

; Giacaman, Rodrigo A

Acta Odontológica Latinoamericana

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Dez 2023, Volume 36 Nº 3 Páginas 183 - 190

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Aim To prepare a consensus document of the cariology contents and competences included in the curriculum for the dentistry degree at Argentine dental faculties/schools Materials and Method Planning the process in stages: Stage 1- Diagnosis of the situation (Google Form) and invitation to participate extended to the 20 academic units (AU) that offer dentistry degrees. Stage 2- Assessment process of Content (C) and Competences (I) agreements in the five domains: D1 Basic Sciences, D2 Risk and diagnosis of dental caries, D3 Decision-making for non-invasive treatments, D4 Decision-making for invasive treatment, and D5 Evidence-based cariology at community level. Stage 3- Consensus. Stages 2 and 3 were held in Workshop format in virtual mode (W) Results Stage 1- Of the total 20 Google forms sent to the AU, 13 responses were received: 7 from National Universities and 6 from Private Universities. All participants agreed to be part of the consensus. Stage 2- W: 20 representatives from 10 AU participated. It began with a contextualizing conference, after which the representatives were divided into 5 groups to assess the agreements of each D. Stage 3- The Cariology Curriculum document was organized into 5 Domains, and 23 C and 31 I of clinical application were defined for teaching cariology. The contents and competences for each domain were agreed upon. The final document was sent to all W participants for their approval and dissemination in each AU involved Conclusion Cariology contents were defined for dentistry students at Universities in the Argentine Republic.

RESUMEN Objetivo Elaborar un documento de consenso de los contenidos y competencias de cariología en el currículo para las facultades/escuelas de odontología argentinas, a nivel del grado Materiales y Método El proceso de creación se efectuó en etapas: 1- Diagnóstico de situación (Formulario electrónico) e invitación a participar a las 20 unidades académicas (UA) donde se imparte la carrera de odontología. 2- Proceso de valoración de acuerdos de Contenidos (C) y Competencias (I) en los cinco dominios (D): D1: Ciencias Básicas; D2: Riesgo y diagnóstico de caries dental; D3: Toma de decisiones tratamientos no invasivos; D4: Toma de decisiones para el tratamiento invasivo y D5: Cariología basada en la evidencia a nivel comunitario. 3- Etapa de consenso. Las etapas 2 y 3 se efectuaron en formato de Workshop en modalidad virtual (W) Resultados Etapa 1: Del total de 20 formularios enviados a las UA se recibieron 13 respuestas (65%), 7 (53,8%) de Universidades Nacionales y 6 (46,1%) de gestión Privada. El 100% de los participantes estuvieron de acuerdo en formar parte del consenso. Etapa 2: W: Participaron 20 representantes de 10 UA. El proceso se inició con una conferencia contextualizadora, posteriormente los representantes fueron divididos en 5 grupos para la valoración de acuerdos de cada D. Etapa 3: El documento de658. 658.l Currículo en Cariología se organizó en 5 Dominios. Se definieron 23 C y 31 I de aplicación clínica para la enseñanza de la Cariología. Se consensuaron los contenidos y las competencias para cada uno de los dominios. El documento final fue enviado a todos los participantes del W para su aprobación y difusión en cada una de las UA involucradas Conclusión En base al trabajo realizado se determinó un consenso de competencias y contenidos en cariología para estudiantes de grado de Odontología, de las Universidades de la República Argentina.

https://doi.org/10.54589/aol.36/3/183

Characterization of uterine involution using B-mode ultrasonography, color Doppler and elastography (acoustic radiation force impulse) for assessing postpartum in Santa Inês ewes
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Mariano, Renata Sitta Gomes

; Santos, Victor José Correia

; Taira, Augusto Ryonosuke

; Silva, Priscila Del Aguila da

; Rodriguez, Mariana Garcia Kako

; Padilha-Nakaghi, Luciana Cristina

; Simões, Ana Paula Rodrigues

; Maronezi, Marjury Cristina

; Avante, Michelle Lopes

; Uscategui, Ricardo Andres Ramirez

; Lima, Bruna Bressianini

; Feliciano, Marcus Antônio Rossi

; Teixeira, Pedro Paulo Maia

; Vicente, Welter Ricardo Russiano

Animal Reproduction

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2023, Volume 20 Nº 2 elocation e20220110

Resumo: En | Texto: En | PDF: En

Abstract The aim of this study was to investigate uterine involution using ultrasonography techniques during postpartum. Postpartum ultrasonography evaluation (B-mode, color Doppler and Acoustic Radiation Force Impulse elastography) of the uterus was performed by transabdominal approach at immediate after birth and sequentially every 48 hours, during 30 days. The uterine echotexture did not present significant variations (P >0.05) being homogeneous in most evaluations; echogenicity of the uterus increased along the evaluation period (P =0.0452). Progressive and remarkable decrease of the total uterine diameter (UD) were observed (P <0.0001), especially during the first days postpartum. The thickness of uterine wall gradually decreased, as well the endometrial, myometrium and lumen diameters (P <0.0001). Uterine blood flow was assessed by Doppler and decreased during postpartum period, being significantly lower (P=0.0225) on the 30th day of postpartum. Uterine parenchyma presented as homogeneous dark areas (not deformable) on qualitative ultrasound elastography and the means shear velocity values of the uterine wall on quantitative elastography did not differ. This is the first study that evaluate the stiffness of uterine wall in healthy ewes, providing baseline data about quantitative and qualitative stiffness of the normal uterus, and it may be a useful tool for early diagnosis of uterine alterations during the postpartum period, using the reference parameter established for the assessment of uterine integrity during postpartum period.

https://doi.org/10.1590/1984-3143-ar2022-0110

The drop plate method as an alternative for Azospirillum spp viable cell enumeration within the consensus protocol of the REDCAI network
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Salvo, Luciana P. Di

; García, Julia E.

; Puente, Mariana L.

; Amigo, Josefina

; Anríquez, Analía

; Barlocco, Claudia

; Benintende, Silvia

; Bochatay, Tatiana

; Bortolato, Marta

; Cassán, Fabricio

; Castaño, Carolina

; Catafesta, Melina

; Coniglio, Anahí

; Díaz, Marisa

; Galián, Liliana R.

; Gallace, Eugenia

; García, Patricia

; Salamone, Inés E. García de

; Landa, Marianela

; Liernur, Germán

; Maneiro, María Laura

; Massa, Rosana

; Malinverni, Julieta

; Marchessi, Nicolás

; Monteleone, Emilia

; Oviedo, Silvina

; Pobliti, Lucrecia

; Portela, Gabriela

; Radovancich, Débora

; Righes, Silvia

; Rocha, Rosina

; Cáceres, Enrique Rodríguez

; Rossi, Alejandro

; Santella, Gisela

; Tortora, María Laura

; Trejo, Nora

; Valenzuela, José A.

; Vallejo, Daniela

Revista argentina de microbiología

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Jun 2022, Volume 54 Nº 2 Páginas 61 - 70

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen La evaluación de la calidad de los inoculantes comerciales es fundamental para garantizar una adecuada respuesta de los cultivos a la inoculación dentro de un marco de bioseguridad. En este sentido, el objetivo de este trabajo fue la estandarización y validación de la técnica de la microgota para la cuantificación de Azospirillum como metodología alternativa a la técnica de siembra en superficie, propuesta actualmente en el protocolo consenso de la Red de Calidad de Inoculantes, REDCAI. Entre 14 y 25 laboratorios, tanto privados como públicos, participaron de tres ensayos independientes. A partir de ellos se obtuvieron resultados reproducibles y robustos que permiten confirmar que ambas técnicas son equivalentes y concluir que la técnica de recuento por la microgota es una alternativa adecuada para ser incluida dentro del mencionado protocolo consenso.

Abstract Quality evaluation of commercial inoculants is essential to warrant an adequate cropresponse to inoculation within a biosecurity framework. In this sense, this work is aimed at standardizing and validating the drop plate method for the enumeration of Azospirillum viable cellsas an alternative to the spread plate technique, which is currently proposed in the consensusprotocol of the REDCAI network. Between 14 and 25 private and public laboratories partici-pated in three independent trials. We obtained consistent and robust results that allowed toconfirm that both techniques are equivalent, concluding that the drop plate method is an alternative enumeration technique that is adequate to be included in the abovementioned consensusprotocol.

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Doppler sonography of the umbilical and uterine arteries blood flow of pregnant Saanen goats
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Del’Aguila-Silva, Priscila

; Santos, Fabiana Cirino dos

; Santos, Victor José Correia dos

; Uscategui, Ricardo Andres Ramirez

; Padilha-Nakaghi, Luciana Cristina

; Mariano, Renata Sitta Gomes

; Rodriguez, Mariana Garcia Kako

; Amoroso, Lizandra

; Vicente, Wilter Ricardo Russiano

; Feliciano, Marcus Antônio Rossi

Animal Reproduction

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2022, Volume 19 Nº 3 elocation e20220014

Resumo: En | Texto: En | PDF: En

Abstract The objective was to evaluate the blood flow of the uterine artery (UA) and umbilical artery (UMB) in the physiological pregnancy of goats by means of Doppler throughout the gestational period. Twenty-five Saanen goats weighing 55 ± 10 kg and aged between 2 and 5 were evaluated weekly, from the 21st until the 143rd day of gestation, and daily from that period until parturition. Values for peak systolic velocity (PSV), end diastolic velocity (EDV) and resistance (RI) and pulsatility (PI) indices of the uterine and umbilical arteries were determined. The values obtained were correlated with gestational age by Spearman's test, tested for adjustment to regression models and compared with the number of fetuses by ANOVA. The umbilical cord was first visualized at 28 days. Of the variables evaluated, RIUMB and PIUMB correlated with gestational age (p<0.001; and 0.046; respectively) and RIUMB had a low negative correlation with the number of fetuses per pregnancy (p = 0.003; r- Spearman = - 0.218). PSVUMB and EDVUMB values did not correlate with gestational age (p=0.737 and 0.768, respectively), but there was a decrease in the mean values throughout pregnancy (PSVUMB= 0.07; 0.31 and EDVUMB= 0.01; 0.06) as well as the change in the flow pattern of the spectral trace. The mean values of the uterine artery dopplervelocimetric variables PSVUT, EDVUT, PIUT and RIUT did not correlate with gestational age (p= 0.324; 0.372, 0.143; 0.13; respectively). It is expected that the results obtained will contribute to a broader understanding of the hemodynamic changes resulting from pregnancy in goats.

https://doi.org/10.1590/1984-3143-ar2022-0014

Efficacy of intermittent topical 5-fluorouracil 5% and oral nicotinamide in the skin field cancerization: a randomized clinical trial,
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Ferreira, Eliane Roio

; Miola, Anna Carolina

; Lima, Thania Rios Rossi

; Schmitt, Juliano Vilaverde

; Abbade, Luciana Patricia Fernandes

; Miot, Hélio Amante

Anais Brasileiros de Dermatologia

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Dez 2021, Volume 96 Nº 6 Páginas 784 - 787

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1016/j.abd.2020.09.012

Educação em saúde relacionada a sexualidade e Infecções Sexualmente Transmissíveis: Uma revisão integrativa
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Rossi, Letícia Farto de

; Mazzetto, Fernanda Moerbeck Cardoso

; Rezende, Kátia Terezinha Alves

; Marin, Maria José Sanches

; de Oliveira Nardo, Luciana Rocha

New Trends in Qualitative Research

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Jun 2021, Volume 8 Páginas 9 - 17

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo: Introdução: O público adolescente possui uma das taxas mais elevadas de Infecções Sexualmente Transmissíveis (IST), além de demonstrar maiores fatores de exposição em comparação ao público adulto, assim como altos índices de abandono de tratamento além da dificuldade de acesso. O aumento gradativo dos índices de IST neste público evidencia uma importante questão de saúde pública. Objetivos: Analisar como se dá a prática de educação em saúde em relação às IST junto aos estudantes do ensino médio, a partir de uma revisão da literatura. Métodos: Trata-se de uma pesquisa de revisão de literatura na modalidade revisão integrativa, em que foram utilizadas as bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Base de Dados em Enfermagem (BDENF) e Índice Bibliográfico Español en Ciencias de la Salud (IBECS) com total de 24 artigos selecionados, considerando critérios de inclusão e exclusão. Resultados: A prática de educação em saúde encontra-se fragilizada. Os fatores que influenciam direta e negativamente estão ligados a ausência de ações intersetoriais e interesse das próprias instituições de ensino, assim como as respectivas equipes pedagógicas e de saúde. Conclusões: A prática de educação em saúde pode ser implementada de forma em que participem pais, professores e profissionais de saúde juntamente aos estudantes, preconizando pela intersetorialidade e integralidade das ações.

Abstract: Introduction: The adolescent public has one of the highest rates of Sexually Transmitted Infections (STI), in addition to demonstrating greater exposure factors compared to the adult public, as well as high rates of treatment abandonment in addition to the difficulty of access. The gradual increase in STI rates in this public highlights an important public health issue. Goals: To analyze how health education practices in relation to STIs occur with high school students, based on a literature review. Methods: This is a literature review research in the integrative review modality, in which the databases of Latin American and Caribbean Literature in Health Sciences (LILACS), Database of Nursing (BDENF) and Index were used. Bibliographic Español en Ciencias de la Salud (IBECS) with a total of 24 selected articles, considering inclusion and exclusion criteria. Results: The practice of health education is weakened. The factors that directly and negatively influence are linked to the absence of intersectoral actions and the interest of the educational institutions themselves, as well as the respective pedagogical and health teams. Conclusions: The practice of health education can be implemented in a way that parents, teachers and health professionals participate together with students, emphasizing the relevance regarding the insertion of these professionals in order to develop actions that emphasize prevention and promotion practices with an emphasis on sexuality and sexually transmitted infections (STIs).

https://doi.org/10.36367/ntqr.8.2021.9-17 16 downloads

Basal metabolic rate for high-performance female karate athletes
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Marques, Luciana Rossi

Nutrición Hospitalaria

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Jun 2021, Volume 38 Nº 3 Páginas 563 - 567

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Introduction: karate is a millennial martial art, currently inserted in the context of Olympic Combat Sports. However, important scientific gaps still persist in monitoring high-performance athletes, including the basal metabolism measurement of female karate athletes. Aim: to contribute to understanding the applicability of equations for predicting basal metabolic rate in this population. Methods: this is a cross-sectional study with a retro-analytical component, in which data were obtained from the medical records of seven athletes participating in the project "Karate São Paulo Olímpico" (São Paulo Olympic Karate) (KSPO) during their nutrition counseling, including body composition and indirect calorimetry testing, with the aim of comparing these data to basal metabolic rate prediction equations. Results: only one out of the five evaluated equations did not have a significant statistical difference relative to the value obtained by open-circuit indirect calorimetry. Conclusion: in case basal metabolism cannot be measured through standard methodology (calorimetry), Cunningham's prediction equation (1980) would be appropriate to obtain total energy expenditure for high-performance female karate athletes.

Resumen Introducción: el karate es un antiguo arte marcial que actualmente encaja en el contexto de los deportes olímpicos de combate. Sin embargo, aún quedan importantes lagunas científicas para el seguimiento de los deportistas de alto rendimiento, una de las cuales es la determinación del metabolismo basal de las deportistas de karate. Objetivo: contribuir al conocimiento de la aplicabilidad de las ecuaciones predictivas para obtener la tasa metabólica basal de esta población. Métodos: el estudio se caracteriza por ser transversal con un componente retroanalítico, donde se obtuvieron los datos de siete atletas de la historia clínica de cuidado nutricional del proyecto Karate São Paulo Olímpico (KSPO), referidos a la composición corporal y el examen de calorimetría indirecta, con el propósito de compararlos con las ecuaciones predictivas de la tasa metabólica basal. Resultados: solo una de las cinco ecuaciones evaluadas no mostró ninguna diferencia estadísticamente significativa con respecto al valor medido mediante calorimetría indirecta de circuito abierto. Conclusión: sería conveniente, si no existe la posibilidad de obtener un metabolismo basal mediante la metodología de referencia (la calorimetría), utilizar la ecuación predictiva de Cunningham (1980) con el fin de obtener el gasto energético total de las deportistas karatecas de alto rendimiento.

https://doi.org/10.20960/nh.03390

Recommendations of the Brazilian Society of Rheumatology for the use of JAK inhibitors in the management of rheumatoid arthritis
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Bonfiglioli, Karina Rossi

; Mota, Licia Maria Henrique da

; Ribeiro, Ana Cristina de Medeiros

; Kakehasi, Adriana Maria

; Laurindo, Ieda Maria Magalhães

; Giorgi, Rina Dalva Neubarth

; Duarte, Angela Luzia Branco Pinto

; Reis, Ana Paula Monteiro Gomides

; Souza, Mariana Peixoto Guimarães Ubirajara e Silva de

; Brenol, Claiton Viegas

; Pinheiro, Geraldo da Rocha Castelar

; Albuquerque, Cleandro Pires de

; Castro, Charlles Heldan de Moura

; Pinto, Gustavo Luiz Behrens

; Verztman, Jose Fernando

; Muniz, Luciana Feitosa

; Bertolo, Manoel Barros

; Pinto, Maria Raquel da Costa

; Louzada Júnior, Paulo

; Cruz, Vitor Alves

; Pereira, Ivanio Alves

; Freitas, Max Vitor Carioca de

; Cruz, Bóris Afonso

; Paiva, Eduardo

; Monticielo, Odirlei

; Provenza, José Roberto

; Xavier, Ricardo Machado

Advances in Rheumatology

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2021, Volume 61 elocation 70

Resumo: En | Texto: En | PDF: En

Abstract Rheumatoid arthritis (RA) is a chronic and autoimmune systemic inflammatory disease that can cause irreversible joint deformities, with increased morbidity and mortality and a significant impact on the quality of life of the affected individual. The main objective of RA treatment is to achieve sustained clinical remission or low disease activity. However, up to 40% of patients do not respond to available treatments, including bDMARDs. New therapeutic targets for RA are emerging, such as Janus kinases (JAKs). These are essential for intracellular signaling (via JAK-STAT) in response to many cytokines involved in RA immunopathogenesis. JAK inhibitors (JAKi) have established themselves as a highly effective treatment, gaining increasing space in the therapeutic arsenal for the treatment of RA. The current recommendations aim to present a review of the main aspects related to the efficacy and safety of JAKis in RA patients, and to update the recommendations and treatment algorithm proposed by the Brazilian Society of Rheumatology in 2017.

https://doi.org/10.1186/s42358-021-00228-x

10.

Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: children and adolescents
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Nabarrete, Juliana Moura

; Pereira, Andrea Z

; Garófolo, Adriana

; Seber, Adriana

; Venancio, Angela Mandelli

; Grecco, Carlos Eduardo Setanni

; Bonfim, Carmem Maria Sales

; Nakamura, Claudia Harumi

; Fernandes, Daieni

; Campos, Denise Johnsson

; Oliveira, Fernanda Luisa Ceragioli

; Cousseiro, Flávia Krüger

; Rossi, Flávia Feijó Panico

; Gurmini, Jocemara

; Viani, Karina Helena Canton

; Guterres, Luciana Fernandes

; Mantovani, Luiz Fernando Alves Lima

; Darrigo Junior, Luiz Guilherme

; Albuquerque, Maria Isabel Brandão Pires e

; Brumatti, Melina

; Neves, Mirella Aparecida

; Duran, Natália

; Villela, Neysimelia Costa

; Zecchin, Victor Gottardello

; Fernandes, Juliana Folloni

einstein (São Paulo)

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2021, Volume 19 elocation eAE5254

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O Consenso Brasileiro de Nutrição em Transplante de Células-Tronco Hematopoiéticas: crianças e adolescentes foi elaborado com a participação de nutricionistas, médicos nutrólogos e médicos hematologistas pediátricos de 10 centros brasileiros que são referência em transplante de células-tronco hematopoiéticas. O objetivo foi salientar a importância do estado nutricional e da composição corporal durante o tratamento, bem como as principais características relacionadas à avaliação nutricional do paciente. As intenções, ao se estabelecer o consenso, foram aprimorar e padronizar a terapia nutricional durante o transplante de células-tronco hematopoiéticas. O consenso foi aprovado pela Sociedade Brasileira de Transplante de Médula Óssea.

ABSTRACT The Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Children and Adolescents was developed by dietitians, physicians, and pediatric hematologists from 10 Brazilian reference centers in hematopoietic stem cell transplantation. The aim was to emphasize the importance of nutritional status and body composition during treatment, as well as the main characteristics related to patient´s nutritional assessment. This consensus is intended to improve and standardize nutrition therapy during hematopoietic stem cell transplantation. The consensus was approved by the Brazilian Society of Bone Marrow Transplantation.

https://doi.org/10.31744/einstein_journal/2021ae5254

11.

Ultrasonography of the nuchal translucency of healthy and abnormal English Bulldog fetuses
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Pavan, Letícia

; Gasser, Beatriz

; Maronezi, Marjury Cristina

; Cruz, Igor Cezar Kniphoff da

; Carneiro, Rafael Kretzer

; Silva, Priscila

; Ramirez Uscategui, Ricardo Andrés

; Padilha-Nakaghi, Luciana Cristina

; Feliciano, Marcus Antônio Rossi

Animal Reproduction

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2021, Volume 18 Nº 4 elocation e20210023

Resumo: En | Texto: En | PDF: En

Abstract The aim of this study was to measure the nuchal translucency (NT) of canine fetuses to establish reference values for healthy gestational processes and to verify its effectiveness in the diagnosis of congenital abnormalities. On day 34 of gestation, the NT of three fetuses from each of the 26 English bulldog female dogs was measured. The first fetus was the one located immediately cranial to the bladder, the second was selected from the left side of the abdomen, and the third from the right side. The reference values for healthy animals were offset using descriptive statistics. The diagnostic ability of the test to identify fetal malformations was studied using receiver operating characteristic curve analysis. Of the 26 litters, only 18 had healthy fetuses, 4 had fetuses with anasarca, 3 had fetuses with abdominal wall defects, and 1 had both types of abnormalities. The NT was higher in canine fetuses that presented anasarca in the litter than in normal litters (1.8 ± 0.77 mm vs. 1.4 ± 0.48 mm; P = 0.0249), with a cut-off value of NT > 1.45 mm (sensitivity = 61.54%, specificity = 70.18%). NT greater than 1.45 mm seems to be a diagnostic tool for the identification of anasarca during gestation of bulldogs. Considering the unprecedented use of this parameter in canine species and the limitations found during the study, further studies will be needed in order to use it on clinical practice.

https://doi.org/10.1590/1984-3143-ar2021-0023

12.

COMVC-19: A Program to protect healthcare workers’ mental health during the COVID-19 Pandemic. What we have learned
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Fukuti, Pedro

; Uchôa, Caroline Louise Mesquita

; Mazzoco, Marina Flaborea

; Cruz, Isabella D'Andrea Garcia da

; Echegaray, Mariana V.F.

; Humes, Eduardo de Castro

; Silveira, Júlia Belizário

; Santi, Talita Di

; Miguel, Euripedes Constantino

; Corchs, Felipe

; Fatori, Daniel

; Campello, Guilherme

; Oliveira, Gabriel M. de

; Argolo, Felipe C.

; Ferreira, Felipe de M.

; Machado, Gustavo

; Argeu, Adriana

; Oliveira, Graça Maria Ramos de

; Serafim, Antônio de Pádua

; Siqueira, Luciana de Lima

; Rossi, Luciane de

; Rios, Izabel Cristina

; Oliveira, Talita Rodrigues de

; Antoniazzi, Leilane C. K.

; Gagliotti, Daniel Augusto Mori

; Abelama Neto, Emílio

; Oliveira Junior, Paulo Novais de

; Correia, Aline Villalobo

; Gonçalves, Luca Schilling

; Tortato, Liana Silva

; Busato, Wagner Machado Moraes

; Guimarães-Fernandes, Flávio

; Alves, Marcos

; Leite Netto, Oswaldo Ferreira

; Schoueri, Patrícia de Campos Lindenberg

; Roque, Márcio de Assis

; Merlin, Silvia Stahl

; Boer, Giovana Cardoso Machado

; Sallet, Paulo Clemente

; Malbergier, André

; Spedo, Mariana Abrahão

; Kamitsuji, Carla Satie

; Faria, Elizabeth de

; Moreira, Moacyr Vergara de Godoy

; Kaufman, Arthur

; Abdo, Carmita

; Scanavino, Marco de Tubino

; Lancman, Selma

; Tavares, Hermano

; Polanczyk, Guilherme

; Brunoni, André R.

; Forlenza, Orestes V.

; Barros-Filho, Tarcísio Eloy Pessoa de

Clinics

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2021, Volume 76 elocation e2631

Resumo: En | Texto: En | PDF: En

OBJECTIVE: In 2020, the COVID-19 pandemic brought a work and stress overload to healthcare workers, increasing their vulnerability to mental health impairments. In response, the authors created the COMVC-19 program. The program offered preventive actions and mental health treatment for the 22,000 workers of The Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP). This paper aims to describe its implementation and share what we have learned from this experience. METHODS: Workers were able to easily access the program through a 24/7 hotline. Additionally, a mobile phone app that screened for signs and symptoms of emotional distress and offered psychoeducation and/or referral to treatment was made available. Data from both these sources as well as any subsequent psychiatric evaluations were collected. RESULTS: The first 20 weeks of our project revealed that most participants were female, and part of the nursing staff working directly with COVID-19 patients. The most frequently reported symptoms were: anxiety, depression and sleep disturbances. The most common diagnoses were Adjustment, Anxiety, and Mood disorders. CONCLUSIONS: Implementing a mental health program in a multimodal intervention was feasible in a major quaternary public hospital. Our data also suggests that preventive actions should primarily be aimed at anxiety and depression symptoms, with a particular focus on the nursing staff.

https://doi.org/10.6061/clinics/2021/e2631

13.

Assessment of dopperfluxometric indices of maternal-fetal structures in pregnant ewes
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Santos, Victor José Correia

; Rodriguez, Mariana Garcia Kako

; Silva, Priscila Del Aguila da

; Mariano, Renata Sitta Gomes

; Taira, Augusto Ryonosuke

; Padilha-Nakaghi, Luciana Cristina

; Uscategui, Ricardo Andres Ramirez

; Feliciano, Marcus Antonio Rossi

; Oliveira, Maria Emilia Franco

; Moraes, Paola Castro

; Vicente, Wilter Ricardo Russiano

Animal Reproduction

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2021, Volume 18 Nº 2 elocation e20210002

Resumo: En | Texto: En | PDF: En

Abstract The aim of this study was to evaluate the blood flow of the uterine artery, fetal aorta and umbilical artery in the physiological pregnancy of sheep by means of pulsed Doppler throughout the gestational period. Thirty Santa Inês ewes weighing between 45.4±4.3 kg and aged 2 to 5 years were selected. The evaluations were carried out weekly from the 3rd to the 21st gestational week. Peak systolic velocity (PSV), end diastolic velocity (EDV) and resistance index (RI) were obtained. Analysis of variance was performed, and the minimum significant comparison of means was obtained by the BH test with adjusted P<0.05. The results were expressed as mean ± standard error. For the fetal aorta, there was an increase in the EDV values and a decrease in the PSV and RI throughout pregnancy. For the uterine artery, PSV and EDV did not present significant variation, whereas the RI showed a reduction in the last week. Increased EDV values were found for the umbilical artery throughout pregnancy. For the PSV there was no significant difference, as the RI was reduced at the end of pregnancy. The results obtained are expected to contribute to a more complete understanding of the hemodynamic changes resulting from pregnancy.

https://doi.org/10.1590/1984-3143-ar2021-0002 102 downloads

14.

Use of dupilumab on the treatment of moderate-to-severe asthma: a systematic review
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Bassani, Cíntia

; Rossi, Larissa

; Siveris, Kaian

; Sferelli, Rafaella Lorenzon

; Saraiva, Leonardo

; Tanno, Luciana Kase

Revista da Associação Médica Brasileira

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Set 2019, Volume 65 Nº 9 Páginas 1223 - 1228

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Este artigo teve como objetivo fazer uma revisão sistemática sobre o tratamento da asma moderada a grave, administrando Dupilumabe. MÉTODOS Foi realizada uma busca nas plataformas on-line Ebsco, SciELO, PubMed, Medline Bireme, Lilacs e New England Journal of Medicine. Foram selecionadas publicações de 2010 a 2018 referentes a artigos que continham grupos controle, que testaram a validade de Dupilumabe e verificaram a resposta dos pacientes por meio de testes controlados. Para a busca desses artigos, foram utilizadas as seguintes palavras-chave: “Dupilumab”, “asthma”, “Bronchial Asthma” and “Asthma, Bronchial”. E o correspondente em português: “asma”, “Asma brônquica” and “Asma brônquica”. Os critérios de exclusão, revisões de literatura, notícias, artigos sem grupos de controle, artigos sobre diferentes assuntos, estudos de Dupilumabe sobre outras doenças, artigos sobre asma sem uso de Dupilumabe e artigos repetidos em plataformas de busca foram descartados. RESULTADOS A literatura aponta que a medicação apresenta boa resposta no tratamento da asma moderada a grave e auxilia na melhora da função pulmonar, além de resultar em poucos efeitos colaterais. Apresenta boa eficácia, segurança e tolerância pelos pacientes. CONCLUSÕES Dupilumabe é promissor para o tratamento da asma em que a terapia convencional se revela insuficiente. Maiores estudos adicionais são necessários para confirmar a segurança e a eficácia em longo prazo.

SUMMARY OBJECTIVE The objective of this article was to conduct a systematic review of the treatment of moderate-to-severe asthma by administrating Dupilumab. METHODS A search on the online databases EBSCO, Scielo, PubMed, Medline Bireme, Lilacs, and The New England Journal of Medicine was conducted, publications from 2010 to 2018 were selected. The inclusion criteria were articles which contained control groups, tested the validity of Dupilumab, and verified the response of patients through controlled tests. For the search of such articles, the following keywords were used: “Dupilumab”, “asthma”, “Bronchial Asthma” AND “Asthma, Bronchial” AND their correspondent in Portuguese “asma”, “Asma brônquica” and “Asma brônquica”. The exclusion criteria were literature reviews, news, articles without control groups, articles on different subjects, Dupilumab studies on other diseases, articles concerning asthma without the use of Dupilumab, and repeated articles on the databases were discarded. RESULTS The literature considers that the medication shows a good response for the treatment of moderate-to-severe asthma and assists in the improvement of lung function, aside from resulting in few side effects. It presents good efficacy, safety, and tolerance by patients. CONCLUSIONS Dupilumab is promising for the treatment of asthma, whereas conventional therapy is deemed to be insufficient. More additional studies are needed to confirm the long-term safety and effectiveness.

https://doi.org/10.1590/1806-9282.65.9.1223 2663 downloads

15.

Evaluation of functionality in children aged 4-6 years presenting congenital toxoplasmosis and retinochoroiditis
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Brandão, Aline de Oliveira

; Vasconcelos, Galton Carvalho

; Tibúrcio, Jacqueline Domingues

; Rossi, Luciana Drummond de Figueiredo

; Andrade, Gláucia Manzan Queiroz

Cadernos Brasileiros de Terapia Ocupacional

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Jan 2019, Volume 27 Nº 1 Páginas 45 - 53

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Introdução: No Brasil, a toxoplasmose congênita (TC) é a principal causa de deficiência visual na infância. É causa de retinocoroidite, que pode levar à cegueira. Minas Gerais apresenta prevalência de um neonato com TC para cada 770 nascidos vivos. Objetivo: Avaliar funcionalidade visual e tarefas do autocuidado de crianças com TC classificadas em grupos de acordo com a acuidade visual. Método: Estudo transversal com 96 pré-escolares com TC. Realizado exame oftalmológico e avaliada a funcionalidade por dois instrumentos: O teste Avaliação da Visão Funcional (AVIF-2 a 6 anos) e Inventário de Avaliação Pediátrica de Incapacidade (PEDI-versão brasileira). Resultados: As crianças foram classificadas em três grupos conforme a acuidade visual: perda visual moderada/grave (n=16), perda leve (n=39) e visão normal (n=41). Houve diferença significativa no escore total do AVIF-2 a 6 anos entre os três grupos (p=0,001), e entre os grupos com perda visual moderada/grave e visão normal (p<0,0001). Os escores do domínio seguimento visual apresentaram pior resultado (p=0,022). O teste PEDI não mostrou diferença significativa entre os grupos. Não houve correlação entre os escores dos testes aplicados. Conclusão: Crianças com TC e perda visual moderada/grave apresentaram comprometimento da funcionalidade visual com maior prejuízo no seguimento visual. O teste AVIF-2 a 6 anos demonstrou esse comprometimento entre os grupos com diferentes acuidades visuais. O teste PEDI (autocuidado) não mostrou diferença estatística significativa dos escores entre os grupos. O teste AVIF- 2 a 6 anos pode contribuir para intervenção mais objetiva na habilitação visual de crianças com TC e baixa visão.

Abstract Introduction: In Brazil, congenital toxoplasmosis (CT) is the main cause of visual impairment in childhood. It causes retinochoroiditis, which should lead to blindness. Minas Gerais has a prevalence of 1 newborn with congenital toxoplasmosis for every 770 live births. Objective: To evaluate visual functionality and tasks of self-care with TC classified in groups according to a visual acuity. Method: A cross-sectional study with 96 preschoolers with CT. Ophthalmologic examination and assessment of some functionalities were performed: The Functional Vision Evaluation (AVIF-2 at 6 years) and the Pediatric Disability Assessment Inventory (PEDI-Brazilian version). Results: Children were classified into three groups according to visual acuity: moderate / severe visual loss (n=16), low level (n=39) and normal vision (n=41). The chance of difference is not greater than AVIF-2 at 6 years among the three groups (p=0.001), being (p <0.0001) between the groups with moderate/severe visual and normal vision. The domain scores are displayed as the end result (p=0.022). The test PEDI is not able to make a difference between the groups. It is not different between the scores of the tests carried out. Conclusion: Children with CT without moderate / severe visual impairment, compromising visual functionality with greater impairment without visual accompaniment. The AVIF-2 at 6 years test demonstrated the impairment between groups with different visual acuities. The PEDI (self-care) test was not performed with a significant difference in scores between the groups. The AVIF-2 at 6 years test may contribute to the more effective intervention in the visual habilitation of children with CT and low vision.

https://doi.org/10.4322/2526-8910.ctoao1250 1881 downloads

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