Pesquisa | SciELO

Abstract Objectives This study evaluated the radiographic progressions of scoliotic curves higher than 40° in patients with adolescent idiopathic scoliosis (AIS). These subjects waited for the surgical procedure while elective surgeries were on hold during the COVID-19 pandemic. Inadditiontoradiographicprogressions, this studydescribed the quality of life of these patients. Methods This study is a retrospective cohort assessing 29 AIS patients with surgical indications registered in the Brazilian public healthcare service. We compared the scoliotic radiographic measurements in two moments: at the beginning of the interruption of elective surgeries due to the COVID-19 pandemic and when these procedures resumed. Results When comparing the radiographic measurements before and after the suspension of assessments for elective surgeries, we observed a significant increase in main curve angles ( p < 0.001), with variations ranging from 0 to 68° and a median valueof10°.Insecondary curves, weobserved anincreaseinangles fromthe proximal thoracic ( p < 0.001) and lumbar ( p = 0.001) regions. However, the increase in the main thoracic region was not significant ( p = 0.317). Conclusion The suspension of elective surgeries for AIS resulted in a significant increase in the radiographic values of patients' spine deformities. This increase harmed the quality of life of these subjects and their families.

Resumo Objetivos Neste estudo foram avaliadas as progressões radiográficas das curvas escolióticas, acima de 40 graus em pacientes com escoliose idiopática do adolescente (EIA). Os indivíduos analisados aguardavam o procedimento cirúrgico, em período de suspensão das cirurgias eletivas, durante a pandemia de covid-19. Além das progressões radiográficas, nestapesquisafoi descritaaqualidadedevidadestes pacientes. Métodos O artigo refere-se a um estudo de coorte retrospectivo, que avaliou 29 pacientes com EIA com indicação cirúrgica, todos cadastrados no serviço público de saúde brasileiro. As medidas radiográficas escolióticas dos pacientes foram comparadas em dois momentos: no início do período da interrupção de cirurgias eletivas, devido à pandemia de covid-19, e logo após a liberação destas. Resultados A partir da comparação das medidas radiográficas entre as avaliações pré e pós suspensão das cirurgias eletivas, observamos o aumento significativo dos valores angulares da curva principal (p < 0,001), com variações entre 0 e 68°, e mediana de 10°. Em relação às curvas secundárias, observamos um aumento dos valores angulares da região torácica proximal (p < 0,001) e lombar (p = 0,001). Entretanto, o aumento da região torácica principal não foi considerado significativo (p = 0,317). Conclusão A suspensão das cirurgias eletivas, para a correção da EIA resultou em um aumento significativo no valor radiográfico das deformidades das colunas dos pacientes, fator que promoveu um impacto negativo na qualidade de vida de pacientes e familiares.

https://doi.org/10.1055/s-0042-1756318

O uso dos serviços odontológicos no último ano na população brasileira: revisão sistemática com metanálise
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Teixeira, Cinthia Nara Gadelha

; Pereira, Sângela Maria da Silva

; Hilgert, Juliana Balbinot

; Oliveira, Neurinéia Margarida Alves de

; Ribeiro, Cecília Cláudia Costa

; Neves, Matheus

; Thomaz, Erika Bárbara Abreu Fonseca

; Hugo, Fernando Neves

; Alves, Cláudia Maria Coelho

Ciência & Saúde Coletiva

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Abr 2023, Volume 28 Nº 4 Páginas 1087 - 1100

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract The scope of this study was to analyze the factors associated with the use of dental services in Brazil. The review strategy included PubMed, SciELO, LILACS, BBO, EMBASE, Scopus, WOS and Google Scholar databases, in addition to repositories and databases of dissertations and theses. Studies were selected using the PEO (Population/Exposure/Outcomes) strategy. The outcome of this study was the use of dental services in the last year by the Brazilian population, treated as dichotomous variables for the following analyses: ≤ 1 year and > 1 year. Mantel-Haenszel random effect meta-analysis was performed, estimating Prevalence Ratios (PR) and 95% confidence intervals (95%CI). A total of 94 studies were selected. The majority (98%) had a cross-sectional design, with 63% derived from primary data. For the meta-analysis, 25 studies were included. The use of oral health services in the last year was associated with higher education (≥ 8 years of schooling) (PR = 0.49, (95%CI: 0.39-0.60)); higher family income (≥ 2 minimum wages) (RP = 0.79, (95%CI: 0.74-0.84)); and living in urban areas (RP = 0.79, (95%CI: 0.64-0.97)). The availability of dental services in the Unified Health System needs to be made readily accessible to people with lower income, less education and those living in rural areas.

Resumo O objetivo foi analisar os fatores associados ao uso dos serviços odontológicos no Brasil. A estratégia de revisão incluiu as bases PubMed, SciELO, LILACS, BBO, EMBASE, Scopus, WOS e Google Scholar, além de repositórios e bancos de dissertações e teses. Os estudos foram selecionados usando a estratégia PEO (população/exposição/desfechos). O desfecho deste estudo foi o uso dos serviços odontológicos no último ano pela população brasileira, tratado como variáveis dicotômicas para as análises: ≤ 1 ano e > 1 ano. Foi realizada uma metanálise de efeito randômico de Mantel-Haenszel, estimando-se razões de prevalência (RP) e intervalos de confiança de 95% (IC95%). Foram selecionados 94 estudos. A maioria (98%) tinha delineamento transversal, sendo 63% oriundos de dados primários. Para a metanálise, 25 estudos foram incluídos. O uso dos serviços odontológicos no último ano esteve associado com maior escolaridade (≥ 8 anos de estudo) (RP = 0,49, (IC95%: 0,39-0,60)); maior renda familiar (≥ 2 salários-mínimos) (RP = 0,79, (IC95%: 0,74-0,84)); e residir na zona urbana (RP = 0,79, (IC95%: 0,64-0,97)). A oferta de serviços odontológicos no Sistema Único de Saúde precisa ser ampliada entre pessoas com menor renda, menor escolaridade e moradores da zona rural.

https://doi.org/10.1590/1413-81232023284.11452022

Untreated caries and serum vitamin D levels in children and youth of the United States: NHANES 2013-2014
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Rigo, Lilian

; Bidinotto, Augusto Bacelo

; Hugo, Fernando Neves

; Neves, Matheus

; Hilgert, Juliana Balbinot

Brazilian Dental Journal

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Fev 2023, Volume 34 Nº 1 Páginas 99 - 106

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract This study aimed to investigate the association between serum vitamin D levels and untreated caries and determining factors in children and youth. Methodology: This cross-sectional study used data from the National Health and Nutrition Examination Survey (2013-2014). In total, 3,072 participants with ages ranging from 1 to 19 years were included in our sample. The main dependent variable, untreated caries, was defined as having at least one untreated carious surface in any tooth. Serum concentration of 25-hydroxyvitamin D [25(OH)D] was categorized into four groups: ≥75 nmol/ml, 50-74.9 nmol/ml, 25-49.9 nmol/ml, and <25 nmol/ml. Data were analyzed using a binary logistic regression. Results: For children aged 1-5 years, age (OR = 1.68, 95% confidence intervals (95% CI) 1.38-2.04) and low levels of vitamin D (25-49.9 nmol/ml, and <25 nmol/ml: OR = 2.55, 95% CI 1.06-6.13) were associated with untreated caries. For children aged 6-11 years, low levels of vitamin D (50-74.9 nmol/ml: OR=1.45, 95% CI 1.16-1.82) remained associated with untreated caries. No associations were found in those between 12 and 19 years of age. Conclusion: Our findings show an association between low levels of 25(OH)D and untreated caries in children between 1 and 11 years of age, suggesting that this nutrient might interfere in the caries process.

Resumo Este estudo teve como objetivo investigar a associação entre os níveis séricos de vitamina D e cárie dentária não-tratada e fatores determinantes em crianças e jovens. Metodologia: Este estudo transversal utilizou dados da Pesquisa Nacional de Saúde e Nutrição (2013-2014). No total, 3.072 participantes com idades entre 1 e 19 anos foram incluídos em nossa amostra. A principal variável dependente, cárie não-tratada, foi definida como pelo menos uma superfície de cárie não-tratada em qualquer dente. A concentração sérica de 25-hidroxivitamina D [25(OH)D] foi categorizada em quatro grupos: ≥75 nmol/ml, 50-74,9 nmol/ml, 25-49,9 nmol/ml e <25 nmol/ml. Os dados foram analisados por meio de regressão logística binária. Resultados: Para crianças de 1 a 5 anos, idade (OR = 1,68, intervalo de confiança de 95% (IC 95%) 1,38 a 2,04) e baixos níveis de vitamina D (25 a 49,9 nmol/ml e <25 nmol/ml: OR = 2,55, IC 95% 1,06-6,13) foram associados a cárie não-tratada. Para crianças de 6 a 11 anos, baixos níveis de vitamina D (50 a 74,9 nmol/ml: OR = 1,45, IC 95% 1,16 a 1,82) permaneceram associados à cárie não-tratada. Não foram encontradas associações naqueles entre 12 e 19 anos de idade. Conclusão: Nossos achados mostram uma associação entre baixos níveis de 25(OH)D e cárie não-tratada em crianças de 1 a 11 anos, sugerindo que este nutriente pode interferir no processo da cárie dentária .

https://doi.org/10.1590/0103-6440202305123

Artificial intelligence and pain: opportunities and challenges for research and clinical practice pain
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Reis, Felipe J. J.

; Neves, Gabriela de Assis

; Carvalho, Matheus Bartholazzi Lugão de

BrJP

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Jan 2023, Volume 6 Nº 1 Páginas 1 - 2

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.5935/2595-0118.20230016-en

Artificial intelligence and pain: opportunities and challenges for research and clinical practice
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Reis, Felipe J. J.

; Neves, Gabriela de Assis

; Carvalho, Matheus Bartholazzi Lugão de

BrJP

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2023, Nº ahead

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.5935/2595-0118.20230016-en

O uso dos serviços odontológicos no último ano na população brasileira: revisão sistemática com metanálise
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Teixeira, Cinthia Nara Gadelha

; Pereira, Sângela Maria da Silva

; Hilgert, Juliana Balbinot

; Oliveira, Neurinéia Margarida Alves de

; Ribeiro, Cecília Cláudia Costa

; Neves, Matheus

; Thomaz, Erika Bárbara Abreu Fonseca

; Hugo, Fernando Neves

; Alves, Cláudia Maria Coelho

Ciência & Saúde Coletiva

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2023, Volume 28 Nº 4 Páginas 1087 - 1100

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232023284.11452022

Integrality, absenteeism and resolubility of specialized care for pediatric patients: a cross-sectional study
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GOUVÊA, Daiana Back

; NEVES, Matheus

; RODRIGUES, Jonas de Almeida

Brazilian Oral Research

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2023, Volume 37 elocation e058

Resumo: En | Texto: En | PDF: En

Abstract Dental Specialties Centers (CEOs) are clinics representing part of the secondary oral health care system of the Brazilian Unified Health System (SUS). Pediatric dentistry is not a requirement for service accreditation. However, the CEO of the Federal University of Rio Grande do Sul (CEO-UFRGS) has provided dental care for children aged 3–11 years since 2017. The utilization rates of health services are influenced by absenteeism. Therefore, evaluation of absences for dental appointments is of primary importance. This study aimed to evaluate referral characteristics, absenteeism, and resolubility of pediatric dentistry appointments at the CEO-UFRGS. This retrospective cross-sectional study was conducted at the Dental Teaching Hospital of the university and analyzed secondary data from referrals and medical records. From August 2017 to December 2019, 167 referrals and 96 medical records were reviewed, from which data of individual variables related to the referral process and treatment were collected. Data were collected by a single trained examiner and analyzed using SPSS software. The main reasons for referral to secondary care were dental caries and pulpal or periapical diseases associated with difficult-to-manage behavior. An absenteeism rate of 28.1% at the first pediatric dental visit and a resolution rate of 65.6% were found. Binary logistic regression analysis indicated that each day of waiting for specialized care resulted in a 0.3% of higher chance of absence for appointment. This also increased the chance by 0.7% in child who attended the first visit to complete treatment, suggesting that the waiting time for attendance was associated with absenteeism and resolubility. Public policies that expand providing child dental care in secondary care are recommended to improve access to and resolubility of services.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0058

Diferenças entre os Sexos nos Desfechos de Pacientes com Infarto do Miocárdio com Supradesnivelamento do Segmento ST Submetidos à Intervenção Coronária Percutânea Primária
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Milan, Victoria B.

; Alves, Yasmin F. S.

; Machado, Guilherme P.

; Araujo, Gustavo Neves de

; Krepsky, Ana Maria

; Chies, Angelo

; Niches, Matheus

; Fracasso, Julia

; Goncalves, Sandro Cadaval

; Wainstein, Marco

; Polanczyk, Carisi Anne

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 Nº 6 elocation e20220673

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background Several studies have shown that women are usually undertreated and have worse outcomes after ST-segment elevation myocardial infarction (STEMI), hence the need to investigate questions related to sex in Brazil to better deal with the problem. Objective To determine whether female sex is still associated with adverse events in a contemporary cohort of patients with STEMI undergoing primary percutaneous coronary intervention (pPCI). Methods This was a prospective cohort study of STEMI patients submitted to pPCI in a tertiary university hospital between March 2011 and December 2021. Patients were categorized into groups based on their sex at birth. The primary clinical outcome was long-term MACCE. Patients were followed-up for up to five years. All hypothesis tests had a two-sided significance level of 0.05. Results Among 1457 patients admitted with STEMI in the study period, 1362 were included and 468 (34.4%) were women. Female patients had a higher prevalence of hypertension (73% vs. 60%, p <0.001), diabetes (32% vs. 25%, p=0.003) and Killip class 3-4 at hospital admission (17% vs. 12%, p=0.01); TIMI risk score was higher among women (4 [2, 6] vs. 3 [2, 5], p<0.001). In-hospital mortality was not different between groups (12.8% vs. 10.5%, p=0.20). In-hospital MACCE (16.0% vs. 12.6%, p=0.085) and long-term MACCE (28.7% vs. 24.4%, p=0.089) were numerically higher in women, with borderline significance. After multivariate analysis, female sex was not associated with MACCE (HR = 1.14; 95% CI 0.86 – 1.51; p = 0.36). Conclusion In a prospective cohort of STEMI patients submitted to pPCI, female patients were older and had more comorbidities at baseline, but no significant differences were found in terms of long-term adverse outcomes.

Resumo Fundamento Vários estudos têm mostrado que as mulheres não recebem tratamento adequado e apresentam piores desfechos após infarto agudo do miocárdio com supradesnivelamento do segmento ST (IAMCSST). Por isso, é necessário investigar questões relacionadas ao gênero para melhor lidar com esse problema no Brasil. Objetivo Determinar se existe associação entre o sexo feminino e eventos adversos em uma coorte contemporânea de pacientes com IAMCSST submetidos à intervenção coronária percutânea primária (ICPp). Métodos Este foi um estudo prospectivo do tipo coorte de pacientes com IAMCSST submetidos à ICPp em um hospital universitário terciário entre março de 2011 e dezembro de 2021. Os pacientes foram categorizados em grupos de acordo com o sexo ao nascimento. O primeiro desfecho clínico foi ECAM em longo prazo. Os pacientes foram acompanhados por um período máximo de cinco anos. Um nível de significância bilateral de 0,05 foi aplicado em todos os testes de hipóteses. Resultados Entre os 1457 pacientes internados por IAMCSST no período do estudo, 1362 foram incluídos e 468 (34,4%) eram do sexo feminino. As mulheres apresentaram maior prevalência de hipertensão (73% vs. 60%, p<0,001), diabetes (32% vs. 25%, p=0,003) e classe Killip 3-4 na internação (17% vs. 12%, p=0,01); o escore de risco TIMI foi maior nas mulheres [4 (2, 6) vs. 3 (2, 5), p<0.001]. A mortalidade hospitalar não foi diferente entre os grupos (12,8% vs. 10,5%; p=0,20). Os ECAMs foram numericamente maiores nas mulheres que nos homens tanto durante a internação (16,0% vs. 12,6%, p=0,085) como em longo prazo (28,7% vs. 24,4%, p=0,089), com significância limítrofe. Após a análise multivariada, o sexo feminino não foi associado a ECAMs (HR = 1,14; IC95% 0,86 – 1,51; p = 0,36). Conclusão Em uma coorte prospectiva contemporânea de pacientes com IAMCSST submetidos à ICPp, pacientes do sexo feminino apresentaram idade mais avançada e mais comorbidades no basal que os pacientes do sexo masculino, mas não houve diferenças significativas entre os sexos quanto aos desfechos adversos no hospital ou em longo prazo.

https://doi.org/10.36660/abc.20220673

COVID-19 outcomes in people living with HIV: Peering through the waves
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Sales, Thaís Lorenna Souza

; Souza-Silva, Maíra Viana Rego

; Delfino-Pereira, Polianna

; Neves, João Victor Baroni

; Sacioto, Manuela Furtado

; Assis, Vivian Costa Morais de

; Duani, Helena

; Oliveira, Neimy Ramos de

; Sampaio, Natália da Cunha Severino

; Ramos, Lucas Emanuel Ferreira

; Schwarzbold, Alexandre Vargas

; Jorge, Alzira de Oliveira

; Scotton, Ana Luiza Bahia Alves

; Castro, Bruno Mateus de

; Silva, Carla Thais Cândida Alves da

; Ramos, Carolina Marques

; Anschau, Fernando

; Botoni, Fernando Antonio

; Grizende, Genna Maira Santos

; Nascimento, Guilherme Fagundes

; Ruschel, Karen Brasil

; Menezes, Luanna Silva Monteiro

; Castro, Luís César de

; Nasi, Luiz Antônio

; Carneiro, Marcelo

; Godoy, Mariana Frizzo de

; Nogueira, Matheus Carvalho Alves

; Guimarães Júnior, Milton Henriques

; Ziegelmann, Patricia Klarmann

; Almeida, Rafaela Charão de

; Francisco, Saionara Cristina

; Silveira Neto, Sidney Teodoro

; Araújo, Silvia Ferreira

; Avelino-Silva, Thiago Junqueira

; Aliberti, Márlon Juliano Romero

; Pires, Magda Carvalho

; Silva, Eduardo Sérgio da

; Marcolino, Milena Soriano

Clinics

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2023, Volume 78 elocation 100223

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Abstract Objective To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. Methods This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1). They were compared using the Chi-Square or Fisher's Exact tests for categorical variables and the Wilcoxon for numerical variables. Results Throughout the study, 17,101 COVID-19 patients were hospitalized, and 130 (0.76%) of those were infected with HIV. The median age was 54 (IQR: 43.0;64.0) years in 2020 and 53 (IQR: 46.0;63.5) years in 2021, with a predominance of females in both periods. People Living with HIV (PLHIV) and their controls showed similar prevalence for admission to the ICU and invasive mechanical ventilation requirement in the two periods, with no significant differences. In 2020, in-hospital mortality was higher in the PLHIV compared to the controls (27.9% vs. 17.7%; p = 0.049), but there was no difference in mortality between groups in 2021 (25.0% vs. 25.1%; p > 0.999). Conclusions Our results reiterate that PLHIV were at higher risk of COVID-19 mortality in the early stages of the pandemic, however, this finding did not sustain in 2021, when the mortality rate is similar to the control group.

https://doi.org/10.1016/j.clinsp.2023.100223

10.

Ocorrência de depressão e avaliação da capacidade funcional em pacientes com doenças vasculares internados em um serviço de cirurgia vascular
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Aragão, José Aderval

; Neves, Osmar Max Gonçalves

; Aragão, Iapunira Catarina Sant’Anna

; Aragão, Felipe Matheus Sant’Anna

; Lourenço, Bárbara Costa

; Porto, Luciano Conceição

; Marassi, Pedro Henrique Adário

; Reis, Francisco Prado

Jornal Vascular Brasileiro

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2023, Volume 22 elocation e20230082

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background Vascular diseases are associated with significant sequelae and clinical repercussions for the lives of affected patients, which are more serious among the elderly. The consequences of vascular disease, such as limb loss, chronic pain, prolonged hospitalization, and polypharmacy, reduce these patients’ autonomy and independence, influencing their wellbeing and quality of life. Objectives To determine the prevalence of depression and assess functional capacity in patients with vascular diseases admitted to a Vascular Surgery Service. Methods This is a descriptive, cross-sectional study, carried out at the Vascular Surgery Service of a tertiary hospital with a non-random sample of patients selected consecutively. The geriatric depression scale short form (GDS-15) was used to assess depression and the Katz scale was used for functional assessment. Results The prevalence of depression in these patients was 60.6%. Associations were observed between depression and consultation with a family doctor in the last 12 months, alcoholism, claudication, diabetes, and individuals who had had an amputation. Individuals’ Katz index functional capacity scores were significantly associated with sociodemographic variables, conditions related to vascular disease, and hospitalization. Conclusions There was a high prevalence of depression in patients with vascular diseases admitted to a vascular surgery service and important reductions in functional capacity in some groups, such as individuals with low educational levels, those who had chronic pain in the lower limbs, patients with diabetes, and those who had had an amputation.

Resumo Contexto As doenças vasculares estão associadas a importantes sequelas e repercussões clínicas nas vidas dos pacientes acometidos e, em maior relevância, entre os idosos. Consequências da doença vascular como a perda de um membro, dor crônica, internamentos prolongados e a polifarmácia geram, nesses pacientes, perda de autonomia e um grau de dependência, que vão influenciar o bem-estar e a qualidade de vida. Objetivos Determinar a ocorrência de depressão e avaliar a capacidade funcional em pacientes com doenças vasculares internados em um serviço de cirurgia vascular. Métodos Trata-se de um estudo observacional, transversal, prospectivo, realizado no serviço de cirurgia vascular de um hospital terciário, com uma amostra não aleatória selecionada de forma consecutiva. Para avaliar a depressão, foi utilizada a escala de depressão geriátrica resumida e, para a avaliação funcional do indivíduo, foi utilizada a escala de Katz. Resultados A prevalência de depressão nesses pacientes foi de 60,6%. Foi observada associação entre depressão e: consulta com médico do Programa de Estratégia de Saúde da Família nos últimos 12 meses, etilismo, claudicação, diabetes e indivíduos que sofreram amputação. Já em relação à capacidade funcional do indivíduo avaliado através do índice de Katz, ocorreram associações significativas entre variáveis sociodemográficas, condições relacionadas a doença vascular e internamento. Conclusões Existem uma alta prevalência de depressão em pacientes com doenças vasculares internados em um serviço de cirurgia vascular e uma redução importante da capacidade funcional em alguns grupos, como os indivíduos de baixa escolaridade, os que sentiam dor crônica nos membros inferiores, os diabéticos e aqueles que sofreram amputação.

https://doi.org/10.1590/1677-5449.202300821

11.

Characterization of raw and thermochemically-treated mesocarp fibers of Oenocarpus bataua, an Amazon palm
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Cruz, Orimax Monteiro

; Dias, Matheus Cordazzo

; Oliveira, Dhimitrius Neves Paraguassú Smith de

; Silva, Marcela Gomes da

; Souza, Tiago Marcolino de

; Mendes, Lourival Marin

; Matos, Lays Camila

; Bufalino, Lina

CERNE

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2023, Volume 29 elocation e-103219

Resumo: En | Texto: En | PDF: En

ABSTRACT Background: Patauá (Oenocarpus bataua Mart.) is a palm tree belonging to the botanical family Arecaceae that occurs throughout the Amazon. Like açaí, an edible pulp is extracted from its fruits, remaining a fiber-rich waste. Revealing the potential of such raw or thermochemically modified fibers for producing bioproducts is a novelty in the literature. Therefore, this work aimed to characterize patauá fibers in natural and alkali-treated conditions to support future bioproduct applications. Alkaline treatments were performed under mechanical stirring combining two NaOH levels (5 and 10%) and two temperatures (80 and 100°C). Morphological characterization was performed by light microscopy and scanning electron microscopy (SEM). The contents of the structural and non-structural chemical components were determined, and chemical groups were evaluated by Fourier-transform infrared spectroscopy (FTIR). The physical characterization included moisture content, apparent density, and water absorption tests. Results: The macerate revealed short fibers with typical elongated morphology, mean cell wall thickness (4.10 µm) greater than the mean lumen width (3.01 µm), and mean length of 445 µm. The alkaline treatments partially individualized the fibers from bundles, cleaned extractives from the surface, and unblocked superficial pits by removing silica-rich structures. They substantially removed non-cellulosic components, but FTIR showed condensed lignin exposed on the fiber surface. Density and water uptake increased concerning natural fibers. Patauá’s short length and susceptibility to modification through thermochemical treatments that concentrated cellulose up to 50% indicated great potential for developing composites and nanofibers. Regardless of the NaOH content, 100°C was more efficient in concentrating cellulose. Conclusion: Patauá fibers have unique natural characteristics. They occur as flatted fiber bundles, have silicon-rich structures obstructing their superficial pits, and comprise more lignin than cellulose.

https://doi.org/10.1590/01047760202329013219

12.

Amphibian Diversity: Where everything starts to flood, Cáceres Municipality, North Pantanal, Central-West Brazil
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Silva-Alves, Vancleber Divino

; Neves, Matheus Oliveira

; Seba, Mariany de Fatima Rocha

; Santos Filho, Manoel dos

; Silva, Dionei José da

Papéis Avulsos de Zoologia

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2023, Volume 63 elocation e202363033

Resumo: En | Texto: En | PDF: En

Abstract Faunal inventories contribute to our understanding of regional diversity, and are fundamental for policy and decision-making regarding the management and conservation of large natural areas. This study aimed to inventory and compile information on amphibian species occurring in the North Pantanal region, in the municipal limits of Cáceres, Mato Grosso, Brazil. We used three methods to inventory amphibian species: (1) fieldwork, (2) analysis of specimens deposited in scientific collections, and (3) literature reviews. We registered 49 amphibian species in Cáceres. Of them, 48 species belonged to the Anura order and were distributed across eight families and 20 genera, and one species belonged to the Gymnophiona order (Siphonops paulensis). The families Leptodactylidae (20 spp.) and Hylidae (17 spp.) were dominant in terms of richness, accounting for 75.5% of all species found in Cáceres. The remaining families had between four and one species each. The municipality is strongly influenced by non-forested formations (e.g., the Cerrado and Pantanal) and presents a high species richness for a non-forested location in Brazil. Our findings highlight Cáceres as one of the richest areas in amphibian species in the North Pantanal region, expanding our knowledge regarding frog diversity. This study provides a foundation for future conservation strategies and additional assessments of amphibian species in light of potential population declines and other emerging threats.

https://doi.org/10.11606/1807-0205/2023.63.033

13.

TNF-alpha and IL-17 cytokine levels in Brazilian patients with ankylosing spondylitis after anti-TNF therapy
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Lara-Armi, Fernanda Formaggi

; Visentainer, Jeane Eliete Laguila

; Braga, Matheus

; Zacarias, Joana Maira Valentini

; Rocha-Loures, Marco Antônio

; Neves, Janisleya Silva Ferreira

; Moliterno, Ricardo Alberto

; Sell, Ana Maria

Brazilian Journal of Pharmaceutical Sciences

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2023, Volume 59 elocation e22746

Resumo: En | Texto: En | PDF: En

Abstract The aim of this study was to evaluate tumor necrosis factor alpha (TNF-α), interleukin (IL)- 17A/F levels in the serum of ankylosing spondylitis (AS) patients after anti-TNF therapy, in order to understand how these cytokines are involved in this therapeutic response. Forty-four AS patients were included in the study: thirty using anti-TNF therapy were classified according to their therapy response as responders (15) and non-responders (15) and 14 without anti-TNF therapy were classified as AS control. Fifteen healthy individuals formed the control group. Serum levels of TNF-α were determined using Luminex technology and for IL-17A and IL-17F using ELISA. The non-responder patients presented higher serum levels of TNF-α than the responders and AS control; the same results were found when HLA-B*27 positive or negative patients were separately analyzed. IL-17A and IL17F serum levels were similar for all groups. According to the clinical disease activity, AS patients with BASDAI ≥4 had higher serum levels of TNF-α than AS patients with BASDAI <4. Positive correlation was found between TNF-α levels and BASDAI. In AS patients, TNF-α serum levels were associated with anti-TNF therapy and disease activity independently of HLA-B*27, and IL-17A and IL-17F were not related to anti-TNF treatment.

https://doi.org/10.1590/s2175-97902023e22746

14.

Monitoramento da carga viral de SARS-CoV-2 em águas residuais na cidade de Goiânia: epidemiologia baseada em esgoto e um sistema de alerta precoce para COVID-19
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Mendes, Geovana de Melo

; Estrela, Paulo Felipe Neves

; Souza Junior, Marcio Neres de

; Brito, Núbia Natália de

; Arruda, Andréa Fernandes

; Augusto, Matheus Ribeiro

; Claro, Ieda Carolina Mantovani

; Duran, Adriana Feliciano Alves

; Cabral, Aline Diniz

; Bueno, Rodrigo de Freitas

; Duarte, Gabriela Rodrigues Mendes

Química Nova

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Out 2022, Volume 45 Nº 10 Páginas 1197 - 1204

Resumo: Pt | Texto: Pt | PDF: Pt

COVID-19 is currently the most critical disease in the world. Thus, several tools have been used in the last two years to contain the spread of SARS-CoV-2. In this perspective, Wastewater-Based Epidemiology (WBE) provides valuable data by including symptomatic, pre-symptomatic, and asymptomatic individuals and anticipating clinical cases. For 37 weeks, the SARS-CoV-2 viral load was monitored in sanitary sewage samples from Goiânia-Brazil. Through pre-concentration, extraction, and purification of viral RNA, followed by RT-qPCR, it was detected in 83.78% (31/37) of the weeks the presence of fragments of the genetic material SARS-CoV-2 with viral loads ranging from 105 to 108 genome copies L-1. The viral load in the wastewater samples was related to the clinical data of the municipality, demonstrating its ability to promote an Early Warning System (EWS). In early 2022, it was possible to predict the increase in clinical cases 3 weeks in advance and issue an alert note to the health authorities. Prevalence estimates ranged from 0.003 to 0.5% and showed good agreement with observed values. Thus, monitoring effluents become another essential tool that can help combat the pandemic’s advance, especially in countries with scarce resources.

https://doi.org/10.21577/0100-4042.20170933

15.

A vivência de estudantes transgênero na universidade
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Viana, Carolina Pinto

; Delgado, Igor Matheus

; Rosa, Anderson

; Neves, Vanessa Ribeiro

; Siqueira, Lucíola D’Emery

Acta Paulista de Enfermagem

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2022, Volume 35 elocation eAPE01966

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Objetivo Compreender a vivência de estudantes transgênero na universidade. Métodos Estudo qualitativo, realizado com método da História Oral Temática. Foram realizadas entrevistas com nove estudantes trans de uma universidade pública do estado de São Paulo. Utilizou-se a técnica de bola de neve para selecionar tais participantes, que responderam às questões do roteiro semiestruturado. Os depoimentos foram gravados, transcritos, transcriados e submetidos à análise de conteúdo. Resultados Emergiram três categorias: “Ser trans”, “A vivência na universidade” e “Apoio ao(à) estudante trans na universidade”. Embora tenham-se percebido como pessoas trans ainda na infância, o processo transexualizador teve início concomitante ao ingresso na universidade. Esse ambiente, considerado heteronormativo e transfóbico, potencializou sentimentos de insegurança e não pertencimento, o que comprometeu a permanência estudantil. O apoio de outros estudantes e ações institucionais foram apontados como possibilidades de enfrentamento dessas dificuldades. Conclusão Garantir a permanência de estudantes trans na universidade depende da criação de políticas de inclusão específicas para essa população e que envolvam toda a comunidade acadêmica. Assim, ações concretas de combate à transfobia e promoção do bem-estar desses estudantes poderão transformar a universidade num local seguro e acolhedor.

Abstract Objective To understand transgender students’ experience at college. Methods This is a qualitative study, carried out using the Thematic Oral History method. Interviews were conducted with nine trans students from a public college in the state of São Paulo. The snowball technique was used to select such participants, who answered the semi-structured script questions. The testimonies were recorded, transcribed, transcreated and submitted to content analysis. Results Three categories emerged: Being a trans; The college experience; Support for trans students at college. Although they perceived themselves as trans people in their childhood, the transsexualization process began concomitantly with their admission to college. This environment, considered heteronormative and transphobic, potentiated feelings of insecurity and non-belonging, which compromised student permanence. The support of other students and institutional actions were pointed out as possibilities to face these difficulties. Conclusion Ensuring the permanence of trans students at college depends on the creation of specific inclusion policies for this population and that involve the entire academic community. Thus, concrete actions to combat transphobia and promote the well-being of these students can transform the college into a safe and welcoming place.

Resumen Objetivo Comprender la vivencia de estudiantes transgénero en la universidad. Métodos Estudio cualitativo, realizado con el método de la historia oral temática. Se encuestó a nueve estudiantes trans de una universidad pública del estado de São Paulo. Se utilizó la técnica de bola de nieve para seleccionar a los participantes, que respondieron las preguntas del guion semiestructurado. Los relatos fueron grabados, transcriptos, transcreados y sometidos a análisis de contenido. Resultados Surgieron tres categorías: “Ser trans”, “La vivencia en la universidad” y “Apoyo al(a la) estudiante trans en la universidad”. A pesar de haberse percibido como personas trans en la infancia, el proceso de transexualización comenzó simultáneamente al ingreso a la universidad. Este ambiente, considerado heteronormativo y transfóbico, potencializó sentimientos de inseguridad y no pertenencia, lo que comprometió la permanencia estudiantil. El apoyo de otros estudiantes y acciones institucionales fueron señaladas como posibilidades de afrontamiento a estas dificultades. Conclusión Garantizar la permanencia de estudiantes trans en la universidad depende de la creación de políticas de inclusión específicas para esta población y que incluyan a toda la comunidad académica. De esta forma, acciones concretas de combate a la transfobia y de promoción del bienestar de estos estudiantes podrán transformar la universidad en un lugar seguro y acogedor.

https://doi.org/10.37689/acta-ape/2022ao019666

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