Empirical studies have pointed out that academic mobility can increase social capital, contribute to collaborations, and directly influence overall career success (Dueñas-Fernández, Iglesias-Fernández & Llorente-Heras, 2013). However, it is also known that both academic mobility and international scientific collaborations can be negatively impacted by gender inequality. Regarding international mobility, women are underrepresented in all areas of knowledge (Momeni et al., 2022). In science, immobility or low mobility is commonly associated with slower career progression; scarce opportunities to hold coordination and management positions ("glass ceiling"); less insertion in international collaboration networks; and even abandonment of science (Delicado & Alves, 2013; van der Wal, 2021).   The overload of family functions and the partnering effect (Ackers, 2004) are among the obstacles that women may face, which can limit researchers' displacement opportunities (Momeni et al., 2022). This scenario justifies the importance of exploring the international mobility undertaken by Brazilian researchers to analyze, among other aspects, the possible gender imbalances in academic mobility.  The population investigated in this research will be comprised of Brazilians who have done postdoctoral studies abroad. This selection is because they are more advanced in their professional and training trajectories. The phase after the doctorate makes the researcher more independent and responsible for their research agenda, which would leave them better able to conduct high-impact studies (Nerad et al., 2022). The work aims to design research that evaluates the effect of postdoctoral mobility abroad on employment in the academic career, considering gender inequality and institutional and systemic aspects (such as area of knowledge, academic productivity, and career position) (Aksnes et al., 2019). For this, a consolidated database will be built based on former postdoctoral fellows of the São Paulo Research Foundation (FAPESP) and the triangulation of a set of data sources since there is no consolidated database on mobility and employment ties in the Brazilian case. Next, a comparative study with a descriptive and exploratory design will be carried out between those who had postdoctoral fellowships abroad and those who had postdoctoral fellowships in Brazil without an internship abroad, and which aims, in the future, to enable the carrying out of a quasi-experiment. DESIGN/METHODOLOGY/APPROACH: The research design is descriptive and exploratory, in which a consolidated database is built with information about employment, academic production and curriculum, as well as the completion of internships abroad. Thus, possible patterns and differentiations between the academic trajectories and the characteristics of the individuals will be investigated. The consolidated database is constructed by exploring, collecting and cross-referencing information from various data sources with quality control of the selected variables. First, we will explore the databases made available by FAPESP regarding former postdoctoral fellows to obtain information about the individuals funded between 2012 and 2017, such as name, institutional affiliation and area of knowledge. Such information is necessary for cross-referencing with other databases. In addition, other information from the researchers' records will be checked regarding the percentage of missing values such as gender, race/color, sexual orientation, and age, among others. The time frame will allow the verification of scientific production and insertion in the labor market in the post-doctorate conclusion years. Subsequently, the FAPESP database will be used for triangulation with three other data sources: (i) formal employment records from the Annual Social Information Report (RAIS) of the Ministry of Labor and Social Security; (ii) the résumés available on the Lattes platform of the National Council for Scientific and Technological Development (CNPq); and (iii) the institutional affiliation in the scientific production of a bibliometric study.  FINDINGS OR EXPECTED OUTCOMES:  The results found so far show a discrepant distribution of completed fellowships by knowledge area and a high concentration of destination countries in the Global North. The expected outcomes are the obtaining of different patterns between the effects of mobility of postdoctoral fellows abroad and the effects of the characteristics of individuals (gender) in scientific production and in employment. Thus, enabling the generation and substantiation of hypotheses for future work. ORIGINALITY/VALUE:  The originality of this research is grounded on three factors. Firstly, the increase in knowledge on international mobility, emphasizing the impacts of mobility on the careers of Brazilian scientists and academics and on gender inequality, which is still little explored. Secondly, the increase in the knowledge areas studied and in the number of destination countries. Previous studies usually focused on a few areas, favoring those with low female presence (exact and biological sciences and engineering) and a small group of destination countries (mainly countries of the Global North). Thus, comprehensiveness is one of the innovations of this research, without the prior selection of areas of knowledge or countries of destination. Thirdly, the results will be based on a triangulation of four sets of information, which will complement different types of academic links, validation of research data, and greater reliability.  PRACTICAL/SOCIAL IMPLICATIONS:  Gender asymmetries in access to academic mobility highlight the disparities between men and women in career advancement possibilities, considering the relevance of international experiences in the researchers' curriculum. Along with the discussions of Responsible Research Assessment (RRA), global initiatives from groups such as the Research on Research Institute (RoRI) and the Global Research Council (GRC) are bringing the need to consider Equity, Diversity and Inclusion (EDI) in research practices and activities to the debate. Thus, it is essential to expand the understanding of gender inequalities in international mobility and academic careers, especially in the Brazilian context. This will contribute to implement EDI plans and policies and create mechanisms aimed at gender equity in the generation of academic mobility opportunities in funding agencies. DIRECTIONS FOR FURTHER RESEARCH/LIMITATIONS:  It is anticipated that there will be two main limitations in the research. The first is the difficulty in obtaining information on the characteristics of individuals. Even with the triangulation of several data sources, the information is often low quality or non-existent. The second limitation stems from the need for more robust methodologies that allow greater inferences about the results, which demands future research advances, where methodologies such as the Generalized Propensity Score (GPS) are implemented.

Estudos empíricos têm apontado que a mobilidade acadêmica pode aumentar o capital social, contribuir para colaborações e influenciar diretamente o sucesso geral na carreira (Dueñas-Fernández, Iglesias-Fernández & Llorente-Heras, 2013). No entanto, também se sabe que tanto a mobilidade acadêmica quanto as colaborações científicas internacionais podem ser impactadas negativamente pela desigualdade de gênero. No que diz respeito à mobilidade internacional, as mulheres estão sub-representadas em todas as áreas do conhecimento (Momeni et al., 2022). Na ciência, a imobilidade ou baixa mobilidade é comumente associada a uma progressão de carreira mais lenta; escassas oportunidades de ocupar cargos de coordenação e gerenciamento ("teto de vidro"); menor inserção em redes de colaboração internacional; e até mesmo abandono da ciência (Delicado & Alves, 2013; van der Wal, 2021). A sobrecarga de funções familiares e o efeito de parceria (Ackers, 2004) estão entre os obstáculos que as mulheres podem enfrentar, o que pode limitar as oportunidades de deslocamento dos pesquisadores (Momeni et al., 2022). Esse cenário justifica a importância de explorar a mobilidade internacional realizada por pesquisadores brasileiros para analisar, entre outros aspectos, os possíveis desequilíbrios de gênero na mobilidade acadêmica. A população investigada nesta pesquisa será composta por brasileiros que realizaram estudos de pós-doutorado no exterior. Essa seleção ocorre porque eles estão mais avançados em suas trajetórias profissionais e de formação. A fase após o doutorado torna o pesquisador mais independente e responsável por sua agenda de pesquisa, o que os capacita a conduzir estudos de alto impacto (Nerad et al., 2022). O trabalho tem como objetivo elaborar uma pesquisa que avalie o efeito da mobilidade de pós-doutorado no exterior no emprego na carreira acadêmica, considerando a desigualdade de gênero e aspectos institucionais e sistêmicos (como área de conhecimento, produtividade acadêmica e posição na carreira) (Aksnes et al., 2019). Para isso, será construído um banco de dados consolidado com base em ex-bolsistas de pós-doutorado da Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) e na triangulação de um conjunto de fontes de dados, uma vez que não existe um banco de dados consolidado sobre mobilidade e vínculos de emprego no caso brasileiro. Em seguida, será realizado um estudo comparativo com um desenho descritivo e exploratório entre aqueles que tiveram bolsas de pós-doutorado no exterior e aqueles que tiveram bolsas de pós-doutorado no Brasil sem estágio no exterior, com o objetivo de possibilitar a realização de um quasi-experimento no futuro. DESENHO/METODOLOGIA/ABORDAGEM: O desenho da pesquisa é descritivo e exploratório, no qual será construído um banco de dados consolidado com informações sobre emprego, produção acadêmica e currículo, bem como a realização de estágios no exterior. Assim, serão investigados possíveis padrões e diferenciações entre as trajetórias acadêmicas e as características dos indivíduos. O banco de dados consolidado é construído explorando, coletando e cruzando informações de várias fontes de dados com controle de qualidade das variáveis selecionadas. Primeiramente, exploraremos as bases de dados disponibilizadas pela FAPESP referentes a ex-bolsistas de pós-doutorado para obter informações sobre os indivíduos financiados entre 2012 e 2017, como nome, afiliação institucional e área do conhecimento. Essas informações são necessárias para cruzar com outras bases de dados. Além disso, outras informações dos registros dos pesquisadores serão verificadas em relação à porcentagem de valores ausentes, como gênero, raça/cor, orientação sexual e idade, entre outros. O período permitirá a verificação da produção científica e inserção no mercado de trabalho nos anos de conclusão do pós-doutorado. Em seguida, a base de dados da FAPESP será utilizada para a triangulação com outras três fontes de dados: (i) registros formais de emprego do Relatório Anual de Informações Sociais (RAIS) do Ministério do Trabalho e Previdência Social; (ii) currículos disponíveis na plataforma Lattes do Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); e (iii) a afiliação institucional na produção científica de um estudo bibliométrico. RESULTADOS OU RESULTADOS ESPERADOS: Os resultados encontrados até o momento mostram uma distribuição discrepante de bolsas concluídas por área do conhecimento e uma alta concentração de países de destino no Norte Global. Os resultados esperados são a obtenção de diferentes padrões entre os efeitos da mobilidade de bolsistas de pós-doutorado no exterior e os efeitos das características dos indivíduos (gênero) na produção científica e no emprego. Isso permitirá a formulação e a fundamentação de hipóteses para trabalhos futuros. ORIGINALIDADE/VALOR: A originalidade desta pesquisa está fundamentada em três fatores. Primeiramente, o aumento do conhecimento sobre a mobilidade internacional, enfatizando os impactos da mobilidade nas carreiras de cientistas e acadêmicos brasileiros e na desigualdade de gênero, que ainda é pouco explorada. Em segundo lugar, o aumento nas áreas de conhecimento estudadas e no número de países de destino. Estudos anteriores geralmente se concentravam em algumas áreas, favorecendo aquelas com baixa presença feminina (ciências exatas, biológicas e engenharias) e um pequeno grupo de países de destino (principalmente países do Norte Global). Assim, a abrangência é uma das inovações desta pesquisa, sem a pré-seleção anterior de áreas de conhecimento ou países de destino. Em terceiro lugar, os resultados serão baseados em uma triangulação de quatro conjuntos de informações, que complementarão diferentes tipos de vínculos acadêmicos, validação dos dados de pesquisa e maior confiabilidade. IMPLICAÇÕES PRÁTICAS/SOCIAIS: As assimetrias de gênero no acesso à mobilidade acadêmica destacam as disparidades entre homens e mulheres nas possibilidades de avanço na carreira, considerando a relevância das experiências internacionais no currículo dos pesquisadores. Juntamente com as discussões sobre Avaliação Responsável da Pesquisa (RRA), iniciativas globais de grupos como o Research on Research Institute (RoRI) e o Global Research Council (GRC) estão trazendo a necessidade de considerar a Equidade, Diversidade e Inclusão (EDI) nas práticas e atividades de pesquisa para o debate. Portanto, é essencial ampliar a compreensão das desigualdades de gênero na mobilidade internacional e nas carreiras acadêmicas, especialmente no contexto brasileiro. Isso contribuirá para implementar planos e políticas de EDI e criar mecanismos voltados para a equidade de gênero na geração de oportunidades de mobilidade acadêmica em agências de financiamento. DIREÇÕES PARA PESQUISAS FUTURAS/LIMITAÇÕES: Antecipa-se que haverá duas limitações principais na pesquisa. A primeira é a dificuldade em obter informações sobre as características dos indivíduos. Mesmo com a triangulação de várias fontes de dados, as informações muitas vezes são de baixa qualidade ou inexistentes. A segunda limitação decorre da necessidade de metodologias mais robustas que permitam maiores inferências sobre os resultados, o que exige avanços em pesquisas futuras, onde metodologias como o Escore de Propensão Generalizada (GPS) são implementadas.

Abstract. Introduction : graduation in the health area should equally contemplate the psychomotor, cognitive and affective domains from the problematization of everyday situations of the Unified Health System (SUS). Objective : to evaluate the training of nutritionists based on the integration of knowledge from the teaching-service-community triad, based on Project-Based Learning (PBL) and Collective Portfolio (PC) in the micropolitics of the SUS. Method : a “baby shower” planned and executed by students, guided by a group of teachers, aimed at pregnant women in the SUS network, providing the live work of the concept-tools “alterity”, “bond”, “welcoming”, and “participatory management” was undertaken. Results : records in the CP showed articulation between different knowledge and learning domains in the training of nutritionists by skills. Conclusion: PBL+CP is a powerful and viable teaching-learning tool for the training of professionals capable of working in SUS integrating teachingservice-community.

Resumo Introdução : a formação na área de saúde deve contemplar equanimemente os domínios psicomotor, cognitivo e afetivo a partir da problematização de situações cotidianas do Sistema Único de Saúde (SUS). Objetivo : avaliar a formação do nutricionista a partir da integração de saberes da tríade ensino-serviço-comunidade, a partir da Aprendizagem Baseada em Projetos (ABP) e Portfólio Coletivo (PC) na micropolítica do SUS. Método : Um “chá de bebê” planejado e executado por estudantes, orientado por um grupo de docentes, destinado a gestantes da rede SUS, oportunizando o trabalho vivo dos conceitos-ferramentas ‘alteridade’, ‘vínculo’, ‘acolhimento’, e ‘gestão participativa’ foi empreendido. Resultados : Registros no PC evidenciaram articulação entre diferentes saberes e domínios de aprendizagem na formação do nutricionista por competências. Conclusão : ABP+PC é uma ferramenta de ensino-aprendizagem, potente e viável para a formação do profissional capaz de atuar no SUS integrando ensino-serviço-comunidade.

Abstract Objective: this study aimed to evaluate if there is an association of intake of coffee and its polyphenols with mammographic findings in women treated at a breast care service unit of the Unified Health System (SUS), Brazil. Research methods and procedures: this was a cross-sectional study with 532 women treated at a health service. The participants were divided according to their mammographic reports into two groups: without and with altered findings. Two 24-h dietary recalls were applied and coffee consumption was categorized into three groups (less than 1 cup, 1 to 3 cups, and more than 3 cups). Phenolic acids were determined using the Phenol Explorer program. The intake of polyphenols was calculated by adding the values obtained from the total amount of coffee consumed during the day. The Multiple Source Method (MSM) was applied to analyze the usual intake. Results: of the 532 women, 178 (33.5 %) had altered mammographic findings. The participants' average daily coffee intake was 193.4 mL. No significant association was found between coffee consumption and mammographic findings. However, it was found that the second tertile of polyphenols was a protective factor for breast changes. Conclusion: coffee polyphenols are protective against breast changes in the group evaluated and, thus, can help prevent breast cancer.

Resumen Objetivo: este estudio tuvo como objetivo evaluar si existe una asociación de la ingesta de café y sus polifenoles con los hallazgos mamográficos de mujeres tratadas en una unidad de patología mamaria del Sistema Unificado de Salud (SUS), Brasil. Métodos y procedimientos de investigación: este fue un estudio transversal con 532 mujeres tratadas en un servicio de salud. Las participantes se dividieron de acuerdo con sus informes mamográficos en dos grupos: sin y con hallazgos alterados. Se aplicaron dos registros dietéticos de 24 horas y el consumo de café se clasificó en tres grupos (menos de 1 taza, 1 a 3 tazas y más de 3 tazas). Los ácidos fenólicos se determinaron utilizando el programa Phenol Explorer. La ingesta de polifenoles se calculó sumando los valores obtenidos de la cantidad total de café consumido durante el día. Se aplicó el método de fuentes múltiples (MSM) para analizar la ingesta habitual. Resultados: de las 532 mujeres, 178 (33,5 %) tenían hallazgos mamográficos alterados. La ingesta diaria promedio de café de los participantes fue de 193,4 ml. No se encontró una asociación significativa entre el consumo de café y los hallazgos mamográficos. Sin embargo, se encontró que el segundo tercil de polifenoles era un factor protector para los cambios mamarios. Conclusión: los polifenoles del café son protectores contra los cambios mamarios en el grupo evaluado y, por lo tanto, podrían ayudar a prevenir el cáncer de mama.

Abstract Background Cardiovascular risk factors are prognostic factors in coronavirus disease 2019 (COVID-19) and have been scarcely studied in Brazil. Objective The aim of this study was to assess the impact of cardiovascular risk factors on the outcomes of patients admitted for COVID-19. Methods From July 2020 to February 2021, 200 patients from two public hospitals were enrolled. Patients were included if they had typical symptoms or signs of COVID-19, a positive real-time polymerase chain reaction test (RT-PCR) for COVID-19, and an age above 18 years. This is a prospective, observational, and longitudinal study. Data were collected within 24 h of admission. The primary endpoint was a combination of hospital lethality, mechanical ventilation, hemodialysis, or length of hospital stay >28 days. Continuous variables were compared with the Student’s t-test for independent samples or the Mann-Whitney test. For comparisons of proportions, the χ 2 test was applied. ROC curves and survival curves were constructed. Multivariate logistic regression was performed to identify independent predictors of events. The level of significance was 0.05. Results There were 98 (49%) events during the hospital course, and 72 (36%) died in the hospital. Patients with a primary endpoint were older and more likely to have a history of hypertension, diabetes, chronic obstructive pulmonary disease (COPD), and chronic kidney disease (CKD). Vital signs at admission associated with events were diastolic blood pressure, respiratory rate, and oxygen saturation in ambient air (O 2 Sat). Serum creatinine >1.37 mg/dL at admission had a sensitivity of 51.6 and a specificity of 82% to predict the primary endpoint, with an area under the curve (AUC) of 0.68. In multivariate analysis, age, diabetes, CKD, and COPD were independent predictors of the primary endpoint. Age and CKD were independent predictors of in-hospital lethality. Conclusion Cardiovascular risk factors, such as diabetes and CKD, were related to a worse prognosis in patients hospitalized with COVID-19 in this sample from two public hospitals in the state of Rio de Janeiro.

Abstract Brazil is located between the Equator and Tropic of Capricorn, which allows diverse climates, reliefs, and habitats for arthropods, which sting represents a risk to human health and a public health issue. This manuscript updates the epidemiological data of cases of human envenoming by spiders, scorpions, and insects with medical relevance in Brazil from 2010 to 2021. Epidemiological data were taken using the Brazilian Notifiable Diseases Information System. Statistics of non-parametric data used the Kruskal-Wallis followed by the Nemenyi test. On average, more than 145,000 envenomation and 145 deaths are recorded annually, and more than 60% of deaths are caused by scorpion bites. When the number of deaths was pondered by the number of cases with each arthropod, bees kill the most. Most stings cause mild symptoms and affect men of working age. The incidence decreases during the colder months, which is better noticeable in regions with well-defined seasons. The distribution is distinct among the regions: Southeast, Northeast, and South have the highest rate of bites. The growing number of cases of envenomation reported annually is a serious public health concern, especially involving scorpions, and highlights the importance of studying arthropod venom and improving the therapies.

ABSTRACT The cultivation of cover plants is a strategy for improving the agricultural production environment and providing straw for soil cover in the no-tillage system, in addition to cycling and providing nutrients to succeeding crops. This study aimed to assess the dry matter yield and nutrients accumulation by cover plants grown alone or intercropped in the second crop after soybean and their effects on cotton grown in succession. The treatments were: Urochloa ruziziensis; Pennisetum glaucum (millet); Zea mays (corn); Crotalaria spectabilis; Crotalaria ochroleuca; Cajanus cajan (pigeon pea); corn + U. ruziziensis; C. spectabilis + U. ruziziensis; C. ochroleuca + U. ruziziensis; pigeon pea + U. ruziziensis; corn + C. spectabilis; corn + C. ochroleuca; and corn + pigeon pea. The experimental design consisted of randomized blocks, with four replications, and the experiment was carried out in two crop seasons. In the cotton pre-seeding, the maximum amount of corn straw dry matter was 2,699 kg ha-1, with low macronutrient contents. The pigeon pea intercropped with U. ruziziensis produced between 8,400 and 12,941 kg ha-1 of dry matter, with a maximum content of 223 and 323 kg ha-1 of nitrogen and potassium, respectively. The U. ruziziensis, grown alone or intercropped, provided between 140 and 323 kg ha-1 of potassium in the straw. A high yield is obtained by cotton grown in the no-tillage system in succession to C. spectabilis.

RESUMO O cultivo de plantas de cobertura é uma estratégia para a melhoria do ambiente de produção agrícola e aporte de palhada para cobertura do solo no sistema plantio direto, além de ciclar e disponibilizar nutrientes às culturas sucessoras. Objetivou-se avaliar a produtividade de matéria seca e o acúmulo de nutrientes por plantas de cobertura cultivadas de forma solteira ou consorciada em segunda safra após a soja e seus efeitos sobre o algodoeiro cultivado em sucessão. Os tratamentos foram: Urochloa ruziziensis; Pennisetum glaucum (milheto); Zea mays (milho); Crotalaria spectabilis; Crotalaria ochroleuca; Cajanus cajan (guandu); milho + U. ruziziensis; C. spectabilis + U. ruziziensis; C. ochroleuca + U. ruziziensis; guandu + U. ruziziensis; milho + C. spectabilis; milho + C. ochroleuca; e milho + guandu. O delineamento experimental foi o de blocos ao acaso, com quatro repetições, e o experimento realizado em duas safras agrícolas. Na pré-semeadura do algodão, a quantidade máxima de matéria seca da palhada de milho foi de 2.699 kg ha-1, com baixos conteúdos de macronutrientes. O guandu consorciado com U. ruziziensis produziu entre 8.400 e 12.941 kg ha-1 de matéria seca, com conteúdo máximo de 223 e 323 kg ha-1 de nitrogênio e potássio, respectivamente. A U. ruziziensis, cultivada de forma solteira ou consorciada, disponibilizou na palhada entre 140 e 323 kg ha-1 de potássio. Alta produtividade é obtida pelo algodoeiro cultivado sob sistema plantio direto em sucessão a C. spectabilis.

ABSTRACT Background: Women living with human immunodeficiency virus (HIV) (WLWH) are more likely to be infected with the oncogenic human papillomavirus (HPV). We assessed the prevalence of high-risk (HR) (16/18/31/33/35/39/45/51/52/56/58/59/68/73/82), probable high-risk (pHR) (26/53/66), and low-risk (LR) (6/11/40/42/43/44/54/61/70) HPV types and their associated risk factors. Methods: This cross-sectional study of WLWH aged 18-64 years included one laboratory and eight HIV-specialty healthcare facilities in the pilot network. Descriptive statistics were used to assess sociodemographic and behavioral characteristics. Adjusted analyses were conducted to evaluate risk factors associated with HR and/or pHR HPV infection in WLWH. Results: From May/2021 to May/2022, 1,914 (92.5%) WLWH participated in the pilot study and had valid HPV-DNA results of self-collected vaginal samples. The median age of the participants was 45 years, 60.1% had ≥ 9 years of schooling, 80.5% were ≤ 18 years at first sexual intercourse, and 51.7% had > 4 sexual partners throughout life. The prevalence of any HPV type, HR HPV, pHR HPV, and LR HPV was 65.8%, 49.6%, 16.7%, and 40.0%, respectively. Age was inversely associated with pHR and/or HR-HPV (p < 0.001), and education level was inversely associated with HR-HPV (p = 0.003) types. Any HR or pHR was associated with being single (p = 0.029) and exchanging sex for drugs (p = 0.037). Conclusions: The prevalence of HPV, especially HR HPV, among WLWH is high in Brazil, highlighting the need for HPV screening in this population. Self-collection of vaginal samples is an important strategy for increasing testing access.

Abstract The objective of this study was to compare the protein profile of the acquired enamel pellicle (AEP) formed in vivo in patients with or without gastroesophageal reflux disease (GERD), and with or without erosive tooth wear (ETW). Twenty-four volunteers were divided into 3 groups: 1) GERD and ETW; 2) GERD without ETW; and 3) control (without GERD). The AEP formed 120 min after prophylaxis was collected from the lingual/palatal surfaces. The samples were subjected to mass spectrometry (nLC-ESI-MS/MS) and label-free quantification by Protein Lynx Global Service software. A total of 213 proteins were identified, or 119, 92 and 106 from each group, respectively. Group 2 showed a high number of phosphorylated and calcium-binding proteins. Twenty-three proteins were found in all the groups, including 14-3-3 protein zeta/delta and 1-phosphatidylinositol. Several intracellular proteins that join saliva after the exfoliation of oral mucosa cells might have the potential to bind hydroxyapatite, or participate in forming supramolecular aggregates that bind to precursor proteins in the AEP. Proteins might play a central role in protecting the dental surface against acid dissolution.

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

Abstract This study sought to analyze the practice of physical activity (PA) among university students, during the COVID-19 pandemic, and associated factors. This is a cross-sectional study with an analytical approach, carried out with 857 university students enrolled in higher education institutions in Montes Claros, in the state of Minas Gerais. Data collection was carried out using the Google forms, which was shared via social networks, containing questions regarding sociodemographic profile, physical activity, clinical factors, and behavioral and health habits. A descriptive exploratory analysis of the data was carried out, with frequency distribution of the study variables. Subsequently, bivariate analyses were performed and the associated variables with up to a level of 20% (p ≤ 0.20) were selected for multiple analysis using Poisson Regression. The prevalence non-practice of PA during the pandemic was of 56.8% among college students. Variables, such as being with a partner (PR=1.28), presence of respiratory diseases (PR=1.17), negative self-perception of health (PR=1.37), increased consumption of ultra-processed foods (PR=1.29), and presence of depression (PR=1.21), showed statistically significant associations with the practice of physical activity. We concluded that the non-practice of PA in university students during the social isolation caused by the COVID-19 pandemic is associated with marital status, presence of respiratory diseases, negative self-perception of health, increased consumption of ultra-processed foods, and presence of depression.

Resumo Este estudo buscou analisar a prática de atividade física entre universitários durante a pandemia de COVID19, e os fatores associados. Trata-se de estudo transversal de abordagem analítica, realizado com 857 universitários matriculados em instituições de ensino superior de Montes Claros-Minas Gerais. A coleta de dados foi realizada através do formulário Google forms, divulgado por redes sociais, contendo perguntas referentes ao perfil sociodemográfico, prática de atividade física, fatores clínicos, hábitos comportamentais e de saúde. Realizou-se análise descritiva exploratória dos dados, com distribuição de frequências das variáveis do estudo. Em seguida foram realizadas análises bivariadas e as variáveis associadas até o nível de 20% (p ≤ 0,20) foram selecionadas para a análise múltipla através da Regressão de Poisson. A prevalência de ausência da prática de AF durante a pandemia foi de 56,8% entre os universitários. Variáveis como estar com companheiro (RP=1,28), presença de doenças respiratórias (RP=1,17), autopercepção negativa da saúde (RP=1,37), aumento do consumo de alimentos ultraprocessados (RP=1,29) e presença de depressão (RP=1,21) demonstraram associações estatisticamente significativas com a prática de atividade física. Neste estudo, observou-se elevada prevalência de universitários que não praticam AF durante o isolamento social, sendo associado a diversos fatores, como o estado conjugal, à presença de doenças, hábitos alimentares e a autopercepção do estado de saúde. Dessa forma, tais características podem subsidiar intervenções com o intuito de incentivar hábitos saudáveis e sobretudo, promover a prática de AF como promoção a saúde física e mental.

Self-inflicted lesions are examined from the perspective of psychoanalytic listening to fifteen adolescents who sought help at a walk-in clinic. Psychological suffering among contemporary adolescents often presents in the guise of this problem. Medicalization is critically assessed as the predominant response to such youths. Aided by psychoanalytic references, other modes of understanding the problem are explored, and Freudian theories of anxiety, pain, and symptom formation are deployed. Additionally, Lacanian theory is called upon to highlight the effects of the word and voice of the Other upon the adolescent subject. Two transgender youths presenting with histories of self-aggression lead to specific reflections on the issue.

Se investigan las autolesiones a partir de la escucha psicoanalítica de 15 jóvenes que fueron acudidos en ambulatorio público. El sufrimiento psíquico en la adolescencia contemporánea se presenta cada vez con mayor frecuencia en forma de este tipo de problemas. La medicalización, que ha sido una respuesta dominante para estos jóvenes, es evaluada críticamente. Con la ayuda del marco psicoanalítico, se exploran otras maneras de comprensión del problema, utilizando las teorías freudianas sobre la angustia, el dolor y la formación de síntomas. Con los aportes lacanianos, también se destacan los efectos de la palabra y la voz del Otro en el sujeto adolescente. Dos jóvenes transgénero que tenían un historial de autolesiones llevaron a reflexiones específicas sobre el tema.

Les automutilations sont étudiées à partir de l’écoute psychanalytique de 15 adolescents arrivés en centre ambulatoire. La souffrance psychique de l’adolescence contemporaine se manifeste de plus en plus fréquemment sous cette forme. La médicalisation, qui a été la solution majoritairement adoptée pour ces jeunes, est considérée sous un jour critique. Sont explorées, à l’aide du référentiel psychanalytique, d’autres formes de compréhension de cette problématique, grâce aux théories freudiennes sur l’angoisse, la douleur et la formation des symptômes. Faisant usage des apports lacaniens, sont également mis en relief les effets de la parole et de la voix de l’Autre sur le sujet adolescent. Deux jeunes transgenres présentant un historique d’automutilations ont conduit à des réflexions spécifiques sur le sujet.

As lesões autoprovocadas são investigadas a partir da escuta psicanalítica de 15 adolescentes que chegaram a um ambulatório público. O sofrimento psíquico na adolescência contemporânea apresenta-se com crescente frequência sob a forma desse tipo de problema. A medicalização, que tem sido uma resposta dominante para esses jovens, é avaliada criticamente. Explora-se, com a ajuda do referencial psicanalítico, outros tipos de entendimento da questão, recorrendo-se às teorias freudianas sobre angústia, dor e formação de sintomas. Usando os aportes lacanianos, são destacados, também, os efeitos da palavra e da voz do Outro sobre o sujeito adolescente. Dois jovens transgêneros que apresentavam histórico de autoagressão conduziram a reflexões específicas sobre o tema.

Abstract Clinical practice guidelines (CPG) are developed to align standards of health care around the world, aiming to reduce the incidence of misconducts and enabling more effective use of health resources. Considering the complexity, cost, and time involved in formulating CPG, strategies should be used to facilitate and guide authors through each step of this process. The main objective of this document is to present a methodological guide prepared by the Epidemiology Committee of the Brazilian Society of Rheumatology for the elaboration of CPG in rheumatology. Through an extensive review of the literature, this study compiles the main practical recommendations regarding the following steps of CPG drafting: distribution of working groups, development of the research question, search, identification and selection of relevant studies, evidence synthesis and quality assessment of the body of evidence, the Delphi methodology for consensus achievement, presentation and dissemination ofthe recommendations, CPG quality assessment and updating. This methodological guide serves as an important tool for rheumatologists to develop reliable and high-quality CPG, standardizing clinical practices worldwide. (CPG world resources complexity cost process rheumatology literature drafting groups question search studies achievement updating highquality high worldwide

RESUMO O presente artigo tem como objetivo analisar a obra de arte de Judy Chicago, The Dinner Party, à luz dos conceitos desenvolvidos pela História das Mulheres. Tal relação se dá por meio da interpretação da obra a partir do contexto no qual ela foi concebida, a da segunda onda do movimento feminista, que contribuiu para o desenvolvido da História das Mulheres como um campo teórico. Os estudos inseridos na História das Mulheres, todavia, não se limitam a apenas apontar para a existência das mulheres ao longo da história, mas também suscita o questionamento sobre o motivo e como se dá o seu apagamento. A obra de Chicago, rica em simbolismos, foi escolhida por encerrar esses vieses presentes nesses pressupostos epistemológicos conectando a afirmação de identidades, a recuperação de memórias e a releitura de uma história definida pelo gênero.

ABSTRACT This article aims to analyze Judy Chicago’s work of art, The Dinner Party, in the light of the concepts developed by the Women’s History. Such relationship occurs through the interpretation of the work of Chicago from the context in which it was conceived, that of the second wave of the feminist movement that contributed to the development of the Women’s History as a theoretical field. The studies inserted in the Women’s History, however, are not limited to just pointing out the existence of women throughout History, but also raises questions about the reason and how they were erased. Chicago’s work, rich in symbolism, was chosen precisely because it closed these two biases present in the these epistemological assumptions, connecting the affirmation of identities, the recovery of memories and the re-reading of a History defined by the genre.

RESUMEN Este artículo tiene como objetivo analizar la obra de arte de Judy Chicago, The Dinner Party, a la luz de los conceptos desarrollados por la Historia de las Mujeres. Esta relación se da a través de la interpretación de la obra desde el contexto en el que fue concebida, el de la segunda ola del movimiento feminista, que contribuyó al desarrollo de la historia de las mujeres como campo teórico. Los estudios insertos en la Historia de la Mujer, sin embargo, no se limitan a señalar la existencia de la mujer a lo largo de la historia, sino que también plantean el interrogante sobre el por qué y cómo se produce su borrado. Se eligió la obra de Chicago, rica en simbolismo, porque acaba con estos sesgos presentes en estos supuestos epistemológicos, conectando la afirmación de identidades, la recuperación de memorias y la reinterpretación de una historia definida por el género.