Pesquisa | SciELO

ABSTRACT In an Amazonian floodplain scenario with river flows, the study analyzes the articulation of Primary Care with Specialized Care, seeking to discuss the political and geographical conditions that impact on the formation of the care network in a health region in the Western Amazon. A combination of methodological strategies was adopted: survey of morbidity indicators and the health network, mapping of intercity routes, survey of expenses in Public Health Actions and Services and interviews with managers. Tefé concentrates banking services, judiciary branch, education and security bodies that give it a centrality of functions. However, health does not consider existing flows in the territory to define which municipalities have Tefé as a health reference. Outdated data in the health information systems, combined with the absence of the state government in the regional health planning, support to provide specialized professionals, payment for supplies and the organization of referral-counter-referral flow in the network have been challenges for integrality of the attention in the region, overloading the hub municipality. Despite the progressive increase in health expenses in the analyzed municipalities, the provision of services beyond Primary Care remains a challenge for the Unified Health System (SUS) in the Amazon.

RESUMO Em um cenário de várzea amazônica com fluxos fluviais, o estudo analisa a articulação da Atenção Básica com a Atenção Especializada, buscando discutir as condições políticas e geográficas que impactam na conformação da rede assistencial em uma região de saúde na Amazônia Ocidental. Adotouse uma combinação de estratégias metodológicas: levantamento de indicadores de morbidade e da rede de saúde, mapeamento dos trajetos intermunicipais, levantamento de despesas em Ações e Serviços Públicos de Saúde e entrevistas com gestores. O município de Tefé concentra serviços bancários, poder judiciário, educacional, órgãos de controle e segurança que lhe conferem uma centralidade de funções. Contudo, a saúde não considera os fluxos existentes no território para definição de quais municípios têm Tefé como referência. A defasagem dos dados nos sistemas de informação em saúde, aliada a ausência do ente estadual no planejamento regional de saúde, apoio para provimento de profissionais especializados, pagamento de insumos e organização do fluxo de referência-contrarreferência na rede têm sido desafios para planejar integralidade da atenção na região, sobrecarregando o município-polo. Apesar do aumento progressivo de despesas em saúde nos municípios analisados, a oferta de serviço para além da Atenção Básica permanece sendo um desafio para o Sistema Único de Saúde (SUS) na Amazônia.

https://doi.org/10.1590/2358-289820241408338p

A precarização jurídica das relações de trabalho como fator de sofrimento das(os) trabalhadoras(es) no setor da saúde durante a pandemia de COVID-19
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Militão, João Batista dos Santos

; Maior, Jorge Luiz Souto

; Silva, Luís Fernando

; Barbosa, Swedenberger do Nascimento

; Machado, Maria Helena

; Gomes, Antônio Marcos Freire

; Barreto, José Cláudio Silva

; Aguiar Filho, Wilson

Ciência & Saúde Coletiva

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Out 2023, Volume 28 Nº 10 Páginas 2797 - 2807

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo O artigo analisou o processo de precarização das relações de trabalho no setor da saúde, demonstrando como essa situação gerou sofrimento dos trabalhadores. O texto buscou registrar como a adoção institucional das concepções econômicas neoliberais, de redução das políticas sociais de Estado, acopladas a um histórico de rejeição cultural aos direitos trabalhistas, proporcionou a atração dos mecanismos de precarização do trabalho, notadamente, a terceirização da mão de obra e da prestação de serviços. No segundo momento, o texto aponta as impropriedades jurídicas cometidas, apresentando as consequências da fragilização do vínculo jurídico nas condições de trabalho desses trabalhadores, principalmente no que se refere às jornadas de trabalho e a remuneração, destacando-se, também, o quanto a disseminação desses vínculos representou um fator de rebaixamento geral dos salários e direitos trabalhistas e previdenciários no setor. Foram apresentados, ainda, dados das pesquisas da Fiocruz sobre condições de trabalho durante a pandemia. Conclui mostrando a urgência de se resgatarem os institutos jurídicos trabalhistas que foram abandonados no percurso histórico estudado, para direcionar a novo rumo as políticas públicas na saúde.

Abstract The present article analyzed the process of precarious work relations in the health sector, demonstrating how this situation generated illness and suffering among workers. The text sought to register how the institutional adoption of neoliberal economic conceptions, of the reduction of State social policies, coupled with a history of cultural rejection of labor rights, provided the attraction of mechanisms of precarious work for the public sector, notably, the outsourcing of labor and the provision of services. In a second moment, the text points out the legal improprieties committed, presenting the consequences of the weakening of the legal bond in the working conditions of these workers, mainly regarding working hours and remuneration, also highlighting how much the dissemination of these links represented a factor of a general reduction in wages and labor and social security rights in the sector. Data from Fiocruz surveys on working conditions during the pandemic were also presented. The article concludes by showing the urgency of rescuing the legal labor institutes that were abandoned in the historical path studied in order to guide the public health policies in a new direction.

https://doi.org/10.1590/1413-812320232810.10212023

A precarização jurídica das relações de trabalho como fator de sofrimento das(os) trabalhadoras(es) no setor da saúde durante a pandemia de COVID-19
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Militão, João Batista dos Santos

; Maior, Jorge Luiz Souto

; Silva, Luís Fernando

; Barbosa, Swedenberger do Nascimento

; Machado, Maria Helena

; Gomes, Antônio Marcos Freire

; Barreto, José Cláudio Silva

; Aguiar Filho, Wilson

Ciência & Saúde Coletiva

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Out 2023, Volume 28 Nº 10 Páginas 2797 - 2807

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-812320232810.10212023

Fracture in Irradiated Rat Femur: A Description of an Experimental Model and Evaluation of its Effectiveness
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Soares, Cláudio Beling Gonçalves

; Araújo, Ivana Duval de

; Teixeira, Luiz Eduardo Moreira

; Michelin, Márcia Antoniazi

; Machado, Carla Jorge

; Silveira, Marcelo Peixoto

Revista Brasileira de Ortopedia

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Ago 2023, Volume 58 Nº 4 Páginas 653 - 658

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Objective We aim to describe an experimental model for studying femoral fractures in rats after exposure to ionizing radiation, demonstrating a way to apply a substance for analysis, the method for patterning fracture and irradiation, and how to evaluate its effectiveness based on radiographic studies. Methods We used 24 rats divided into 2 groups of 12 animals each. The STUDY group was exposed to ionizing radiation and treated with saline solution, and the CONTROL group was not exposed to radiation and was treated with saline solution. All animals were subjected to standardized fracture of the right femur that was fixed with intramedullary wire. The efficiency of the bone union was assessed by radiographic exam. Results Fracture healing was more efficient in bones not exposed to ionizing radiation (p = 0.012). All fractures met the criteria of being simple, diaphyseal, transverse or short oblique. Conclusion The experimental model presented is an efficient alternative for the study of fractures in irradiated bones in rats.

Resumo Objetivo Nosso objetivo é descrever um modelo experimental para estudo de fraturas de fêmur em ratos após exposição a radiação ionizante, demonstrando uma forma de aplicação de uma substância para análise, o método de padronização de fratura e irradiação e a forma de avaliação de sua eficácia com base em estudos radiográficos. Métodos Utilizamos 24 ratos divididos em dois grupos de 12 animais cada. O grupo ESTUDO foi exposto à radiação ionizante e tratado com soro fisiológico, enquanto o grupo CONTROLE não foi exposto à radiação e foi tratado com soro fisiológico. Todos os animais foram submetidos à fratura padronizada do fêmur direito e sua fixação com fio intramedular. A eficácia da consolidação óssea foi determinada por exame radiográfico. Resultados A cicatrização de fraturas foi mais eficiente em ossos não expostos à radiação ionizante (p = 0,012). Todas as fraturas atenderam aos critérios de serem simples, diafisárias, transversas ou oblíquas curtas. Conclusão O modelo experimental apresentado é uma boa alternativa para o estudo de fraturas em ossos irradiados em ratos.

https://doi.org/10.1055/s-0042-1758359

[SciELO Preprints] - EFFECTS OF VERBAL INTERVENTIONS PERFORMED BY THE COACH DURING SMALL-SIDED GAMES ON THE TACTICAL PERFORMANCE OF YOUNG SOCCER PLAYERS
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Garozzi, Gabriel Gonçalves, Luiz Guilherme Leonardo, Lucas Costa, Raul Victor da Machado, João Claudio Aquino, Rodrigo

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Data de publicação: 2023-03-27

Resumo: En Es Pt

The aim of this study was to verify the effects of verbal interventions performed by the coach on the tactical performance of young soccer players. 24 under-13 players and a coach with more than 10 years of experience participated in this study. Players were submitted to two conditions: experimental (small-sided games with verbal intervention) and control (small-sdeid games without verbal intervention). The players, in both conditions, played small-sided games in the format Goalkeeper+3 vs. 3+Goalkeeper, lasting 4 minutes. Tactical performance was analyzed using the Football Tactical Assessment System (FUT-SAT), considering the 10 fundamental tactical principles. The categorization of verbal interventions performed by the coach was performed through content analysis. The results show that the verbal interventions used (~90% instructive/direct) positively influenced the defensive tactical performance, however, they had a negative impact on the offensive tactical performance. It is concluded that the coach's verbal interventions can be important pedagogical tools to guide the tactical performance of young players. However, the predominance of direct instructions can compromise the offensive tactical performance during small-sided games in young players. Coaches, therefore, should reflect on how and in what ways to communicate with their players, in an attempt to promote a more representative learning environment.

El objetivo de este estudio fue verificar los efectos de las intervenciones verbales realizadas por el entrenador en el desempeño táctico de jóvenes futbolistas. En este estudio participaron 24 jugadores menores de 13 años y un entrenador con más de 10 años de experiencia. Los jugadores fueron sometidos a dos condiciones: experimental (juegos reducidos con intervención verbal) y control (juegos reducidos sin intervención verbal). Los jugadores, en ambas condiciones, jugaron partidos reducidos en el formato Portero+3 vs. 3+Portero, con una duración de 4 minutos. El desempeño táctico se analizó mediante el Sistema de Evaluación Táctica del Fútbol (FUT-SAT), considerando los 10 principios tácticos fundamentales. La categorización de las intervenciones verbales realizadas por el entrenador se realizó a través del análisis de contenido. Los resultados muestran que las intervenciones verbales utilizadas (~90% instructivas/directas) influyeron positivamente en el desempeño táctico defensivo, sin embargo, tuvieron un impacto negativo en el desempeño táctico ofensivo. Se concluye que las intervenciones verbales del entrenador pueden ser importantes herramientas pedagógicas para orientar el desempeño táctico de los jóvenes jugadores. Sin embargo, el predominio de las instrucciones directas puede comprometer el desempeño táctico ofensivo durante juegos reducidos en jugadores jóvenes. Los entrenadores, por lo tanto, deberían reflexionar sobre cómo y de qué manera comunicarse con sus jugadores, en un intento de promover un entorno de aprendizaje más representativo.

O objetivo deste estudo foi verificar os efeitos das intervenções verbais realizadas pelo treinador sobre o desempenho tático de jovens jogadores de futebol. Participaram deste estudo 24 jogadores da categoria sub-13 e um treinador, com mais de 10 anos de experiência. Os jogadores foram submetidos a duas condições: experimental (jogos reduzidos com intervenção verbal) e controle (jogos reduzidos sem intervenção verbal). Os jogadores, em ambas as condições, realizaram jogos reduzidos no formato Goleiro+3 vs. 3+Goleiro, com duração de 4 minutos. O desempenho tático foi analisado por meio do Sistema de Avaliação Tática no Futebol (FUT-SAT), considerando os 10 princípios táticos fundamentais. A categorização das intervenções verbais realizadas pelo treinador foi realizada por meio da análise de conteúdo. Os resultados mostram que as intervenções verbais utilizadas (~90% instrutivos/diretos) influenciaram positivamente no desempenho tático defensivo, porém, exerceram impacto negativo no desempenho tático ofensivo. Conclui-se que intervenções verbais do treinador podem se constituir ferramentas pedagógicas importantes para orientar o desempenho tático de jovens jogadores. Contudo, a predominância de instruções diretas pode comprometer o desempenho tático ofensivo durante jogos reduzidos em jovens jogadores. Os treinadores, portanto, devem refletir sobre como e de que forma se comunicar com seus jogadores, na tentativa de promover um ambiente de aprendizagem mais representativo.

https://doi.org/10.1590/SciELOPreprints.5796

Post-thaw quality of ram sperm frozen with different concentrations of low-density lipoproteins associated with non-enzymatic antioxidants
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Snoeck, Paola Pereira das Neves

; Câmara, Diogo Ribeiro

; Moura, Luís Cláudio de Oliveira

; Silva, Maíra Corona da

; Machado-Neves, Mariana

; Teixeira-Neto, Milton Rezende

; Henry, Marc

Animal Reproduction

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2023, Volume 20 Nº 1 elocation e20220068

Resumo: En | Texto: En | PDF: En

Abstract The cryopreservation reduces ram sperm quality, decreasing the pregnancy rate of ewes inseminated with thawed sperm. Hence, we aimed to improve the post-thaw quality of ram sperm replacing egg yolk on Tris-Glucose extender with different concentrations of LDL (2 or 8%), associated with the addition of 10 mM non-enzymatic antioxidants (ascorbic acid, hydroxytoluene butylate, ascorbyl palmitate, and trehalose). Semen samples were collected from six rams, split into different treatments, and frozen. After thawing, kinematic (CASA), structural (propidium iodide and carboxyfluorescein diacetate) and functional (hypoosmotic test) sperm membrane integrity was assessed. Total motility, VCL, and LIN were also assessed in thawed samples during 3 h of incubation (38 °C). The results showed that hydroxytoluene butylate at 10 mM in Tris-Glucose extender with 8% LDL improved velocity parameters immediately post-thaw compared with Tris-Glucose egg yolk extender, as well as prevented the reduction of total motility and VCL after incubation. There was no benefit of adding ascorbic acid and trehalose. Moreover, for the first time, it was shown the motility impairment promoted by ascorbyl palmitate to ram sperm.

https://doi.org/10.1590/1984-3143-ar2022-0068

Efficacy of mouthrinses in reducing oral SARS-COV-2 load: a review
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PANNUTI, Claudio Mendes

; REIS, Isabella Neme Ribeiro dos

; SOUZA, Nathalia Vilela

; SOUTO, Maria Luisa Silveira

; SILVA, Carlos Guillermo Benítez

; BEZINELLI, Leticia Mello

; MACHADO, Clarisse Martins

; ROMITO, Giuseppe Alexandre

; VILLAR, Cristina Cunha

Brazilian Oral Research

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2023, Volume 37 elocation e038

Resumo: En | Texto: En | PDF: En

Abstract Accumulated evidence has shown that the oral cavity may be an important reservoir for SARS-CoV-2. Some authors have suggested that the use of mouthrinses could reduce SARS-CoV-2 viral load in the saliva. Thus, the aim of this review was to synthesize evidence about the efficacy of mouthrinses in reducing the salivary viral load of SARS-CoV-2. 2. Nine randomized controlled trials (RCTs) have investigated the efficacy of different mouthrinses in reducing salivary SARS-CoV-2 loads. Various active ingredients have been tested in these trials: 0.5%,1% and 2% povidone-iodine, 0.2% and 0.12% chlorhexidine (CHX), 0.075% cetylpyridinium chloride (CPC), 0.075% CPC with Zinc lactate, 1% and 1.5% hydrogen peroxide (HP), 1.5% HP + 0.12% CHX and ß-cyclodextrin and citrox. The studies reported an intra-group reduction in the salivary levels of the virus, when compared with the baseline. However, the majority of these trials failed to demonstrate a significant inter-group difference between active groups and the control group relative to the decrease in salivary SARS-CoV-2 loads. Although promising, these results should be confirmed by larger trials.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0038

Effect of two diets on the fecundity of ablated and non-ablated female of Macrobrachium amazonicum
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Rocha, Gisele Lima

; Costa, Tiago Viana da

; Machado, Noédson de Jesus Beltrão

; Gualberto, Tomaz Lima

; Muniz Júnior, José Cláudio Bezerra

Acta Scientiarum. Animal Sciences

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2023, Volume 45 elocation e59780

Resumo: En | Texto: En | PDF: En

ABSTRACT. Macrobrachium amazonicum is a species of freshwater shrimp of great importance for aquaculture and to know its reproductive potential, through the study of its fertility is necessary. Therefore, this study aimed to evaluate the effect of two different diets on the reproductive performance of the species, whether or not adopting the ablation procedure. The experiment was carried out in a completely randomized design in a 2 x 2 factorial arrangement, with two types of feed (inert and fresh) and two conditions (ablated and non-ablated females), using six replicates per treatment. After 10 days of spawning, the eggs were removed and counted in their entirety. For each female, three spawns were obtained, totaling 72 samples. The fertility rate, the interval between spawning and the weight gain of the females were analyzed. There was no interaction between the studied factors, except for weight gain, in which ablated females that received fresh feed gained up to three times more weight than non-ablated females. Females that received fresh feed obtained higher fertility (1,373.9 eggs) than those that received only inert feed (1,084.1 eggs). The interval between spawns was 1.6 days shorter in ablated females.

https://doi.org/10.4025/actascianimsci.v45i1.59780

Synthesis and Anticancer Activity of Homodimeric Morita-Baylis-Hillman Adducts Based on 3-Hydroxyindolin-2-one Core
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Coelho, Maísa C.

; Castro, Aleff

; Olegário, Tayná R.

; Cristiano, Rodrigo

; Vaz, Boniek G.

; Santos, Gabriel F. dos

; Machado, Lucas S.

; Militão, Gardênia C. G.

; Silva, Paulo B. N. da

; Vasconcellos, Mário L. A. A.

; Lima-Junior, Claudio G.

Journal of the Brazilian Chemical Society

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2023, Volume 34 Nº 9 Páginas 1273 - 1283

Resumo: En | Texto: En | PDF: En

Cancer treatment represents one of the main scientific study targets today, mainly due to the pronounced side effects arising from chemotherapy. This study reports the synthesis, characterization, and anticancer activity of ten compounds from the Morita-Baylis-Hillman reaction. Ethylene glycol diacrylate was used as a double Michael acceptor in reactions with isatin derivatives to give homodimers of 3-hydroxyindolin-2-one core, recognized in the literature for its extensive pharmacological profile. The use of 1,4-diazabicyclo[2,2,2]octane (DABCO) as a catalyst and room temperature were the optimal conditions for the study reaction. The isolated yields were up to 63%, with most reaction times inferior to 24 h, some as fast as 15 min. The anticancer potential of the synthesized dimers was evaluated in vitro against three cancer strains, resulting in average inhibitory concentrations up to 0.72 µM. It was also found that the best performing homodimers are more active than their monomeric counterparts. Considering the promising selectivity indices observed, the preliminary results obtained here act as a basis for broader tests regarding the effectiveness of homodimeric adducts against cancer cells.

https://doi.org/10.21577/0103-5053.20230038

10.

Productivity and nutrient export in a maize and forage grasses intercropping under semiarid conditions
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PONTE FILHO, Francisco Augusto Machado da

; GUEDES, Fernando Lisboa

; POMPEU, Roberto Cláudio Fernandes Franco

; SAGRILO, Edvaldo

; ANDRADE, Hosana Aguiar Freitas de

; COSTA, Carlos Pedro de Meneses

; SOUZA, Henrique Antunes de

Revista Brasileira de Saúde e Produção Animal

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2023, Volume 24 elocation 20220029

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT The aim was to evaluate the productive performance and nutrient export of maize intercropped with drought-tolerant forage grasses. The experimental design was a randomized blocks in a 2x2x2+1 factorial scheme (two forage grasses species – Massai and Buffel; two forage sowing methods - in the furrow and broadcast; and two forage sowing times - anticipated and simultaneous; and monoculture maize as an additional control), with three replicates. The maize+forage intercropping promoted greater competition for resources, especially water, limiting N uptake, chlorophyll synthesis, and biomass production by maize under semiarid conditions. Early sowing gave forage plants a competitive advantage, favoring forage establishment before or immediately after the sowing of maize. Thus, the simultaneous sowing of forage grasses in a semiarid environment is a more appropriate option considering the importance of high levels of chlorophyll to ensure high photosynthetic activity in maize plants and greater capacity of biomass synthesis. Massai intercropped with maize exhibits a greaterpotential for biomass production than Buffel under semiarid conditions. Maize+Buffel result in highest macronutrient export by maize, while maize+Massai result in highest macronutrient exports by total forage biomass under a semiarid environment. The choice of the forage species and its sowing time in relation to maize are the main determinants of successful intercropping systems under semiarid conditions.

RESUMO O objetivo foi avaliar o desempenho produtivo e a exportação de nutrientes do consórcio de milho com gramíneas forrageiras tolerantes ao estresse hídrico. O experimento foi delineado em blocos casualizados em esquema fatorial 2x2x2+1 (duas espécies de gramíneas forrageiras – Massai e Buffel; dois métodos de semeadura – no sulco e a lanço; e duas épocas de semeadura – antecipada e simultânea; e monocultivo de milho como um controle adicional), com três repetições. O consórcio milho+forragem promoveu maior competição por recursos, principalmente água, limitando a absorção de N, síntese de clorofila e produção de biomassa pelo milho para condições semiáridas. A semeadura precoce deu vantagem competitiva às plantas forrageiras, favorecendo seu estabelecimento antes ou imediatamente após a semeadura do milho. Assim, a semeadura simultânea de gramíneas forrageiras em ambiente semiárido é uma opção mais adequada, considerando a importância de garantir altos teores de clorofila e, consequentemente, alta atividade fotossintética nas plantas de milho para garantir a capacidade de síntese de biomassa.Massai consorciado com milho apresenta maior potencial para produção de biomassa do que Buffel em condições semiáridas.Milho+Buffel resulta em maior exportação de macronutrientes pelo milho, enquanto milho+Massai resulta em maior exportação de macronutrientes pela biomassa forrageira total em ambiente semiárido.A escolha da espécie forrageira e sua época de semeadura em relação ao milho são os principais determinantes do sucesso do consórcio no semiárido.

https://doi.org/10.1590/s1519-994020220029

11.

Selecting tropical wheat genotypes through combining ability analysis
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SILVA, CAIQUE MACHADO E

; NARDINO, MAICON

; MEZZOMO, HENRIQUE C.

; CASAGRANDE, CLEITON RENATO

; LIMA, GABRIEL W.

; SIGNORINI, VICTOR S.

; FREITAS, DAVI S. DE

; BATISTA, CLÁUDIO V.

; REIS, EDÉSIO F. DOS

; BHERING, LEONARDO L.

; OLIVEIRA, ALUÍZIO B. DE

Anais da Academia Brasileira de Ciências

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2023, Volume 95 Supl. 2 elocation e20220760

Resumo: En | Texto: En | PDF: En

Abstract The selection of parents to originate promising base populations, as well as the knowledge of the gene effects controlling agronomic traits by means of diallel, are useful to drive genetic gains in Brazilian tropical wheat breeding programs. The goals of this study were to select tropical wheat parents with a high frequency of favorable alleles and segregating populations with high potential to originate superior progenies through partial diallel analysis. Thus, 14 parents were divided in two groups and crossed in a 7 × 7 partial diallel scheme to originate 49 F1 combinations. After obtaining F2 generation, the populations and the parents were evaluated in the field in the summer of 2021. Days for heading, plant height, rust and yellow spot resistance, and grain yield were evaluated. The data were subjected to partial diallel analysis. There were significant effects of general combining ability for all traits. The specific combining ability effect was significant for days for heading and plant height. The additive gene effects were predominant over the non-additive ones. The parents with the highest frequency of favorable alleles for the traits evaluated were selected in each group. Four populations with high genetic potential to originate superior progenies were selected.

https://doi.org/10.1590/0001-3765202320220760

12.

Requirement for digestible lysine in Nile tilapias (Oreochromis niloticus) with live weight between 500 and 600 g
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Muniz Junior, José Claudio Bezerra

; Haidamus, Suzana Linhares

; Machado, Noédson de Jesus Beltrão

; Dilelis, Felipe

; Brasil, Ronner Joaquim Mendonça

; Quaresma, Débora Vaccari

; Lima, Cristina Amorim Ribeiro de

Acta Scientiarum. Animal Sciences

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2023, Volume 45 elocation e61547

Resumo: En | Texto: En | PDF: En

ABSTRACT. The present study was carried out with the objective of determining the requirements for digestible lysine in Nile tilapia during the 500 to 600 g live weight stage. Isocaloric and isonitrogenous diets were tested with increasing amounts of digestible lysine. L-lysine HCl (78%) were used to replace glutamic acid at increasing levels, resulting in treatments of 9.3, 12.3, 15.3, 18.3 and 21.3 g kg-1 of digestible lysine. Three hundred Nile tilapias with an average weight of 519 ± 27.23 g were used and distributed among 25 tanks. The physical and chemical parameters of the water were pH, dissolved oxygen, salinity, conductivity and temperature. The mortality rate was registered daily. Two slaughters were performed at 28 and 50 days after the beginning of the experiment. It was estimated that an amount of 13.1 g kg-1 of digestible lysine was ideal for obtaining higher WG. Fish slaughtered after 50 days, the digestible lysine requirements were determined to be 14.5 g kg-1 for the lowest carcass humidity and 14.6 g kg-1 for the greatest carcass ethereal extract. Nile tilapias with live weight between 500 and 600 grams require 13.1 g kg-1 of digestible lysine in the diet for greater WG (90.53 g) and better FCR (2.55).

https://doi.org/10.4025/actascianimsci.v45i1.61547

13.

Scientific diving in Brazil: history, present and perspectives
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Leite, Tatiana S.

; Pinheiro, Igor E.

; Berchez, Flávio

; Bertoncini, Áthila A.

; Cima, Oswaldo M. Del

; Demetrescu, Irene E.

; Francini-Filho, Ronaldo B.

; Kikuchi, Ruy K.P

; Machado, Arthur A.

; Maia-Nogueira, Rodrigo

; Martins, Flavio L.

; Mendes, Liana F.

; Rambelli, Gilson

; Sampaio, Claudio L.S.

; Segal, Barbara

; Aguiar, Aline A.

; Auler, Augusto S.

; Barroco-Neto, José

; Bonaldo, Roberta M.

; Buchmann, Francisco S.

; Calippo, Flavio

; Cesar, Augusto

; Gama, Matheus A.C.

; Ghilardi-Lopes, Natalia

; Leão, Zelinda M.A.N.

; Lessa, Guilherme C.

; Menegola, Carla

; Pinheiro, Hudson T.

; Rocha, Luiz A.

; Sabino, José

; Seoane, José C.S.

; Sestokas, Julia

; Tiago, Cláudio C.

; Wegner, Ewerton

; Lotufo, Tito

Ocean and Coastal Research

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2023, Volume 71 elocation e23045

Resumo: En | Texto: En | PDF: En

Abstract Scientific diving (SD) is defined as any diving activity that applies scientific procedures to produce subsidies for studies and technical works in underwater environments. The first report of an underwater scientific study in Brazil dates to the 19th century, in the Abrolhos reefs. Currently, in Brazil, scientific diving has been performed in various areas, from shallow coastal regions to remote and sometimes hard-to-reach places, such as oceanic islands, flooded caves, and icy areas like Antarctica. However, the regulation of SD in Brazil still lacks more concrete actions towards an effective and efficient self-regulation that offers physical safety to practitioners and institutional safeguards for organizations that use it in their research projects. Thus, this article aims to contribute to a better understanding of this critical issue in Brazil and to serve as a reference and incentive for the training of professionals and the development of these activities in the country. It includes: 1) a historical review of SD; 2) a diagnosis of the training and application of SD in Brazil; 3) the evolution of marine sciences in Brazil from the perspective of SD; 4) a review of the use of environmental assessment and underwater conservation techniques in oceans and internal waters; 5) an analysis of the evolution of scientific diver training in Brazil, including a diagnosis on training; 6) the history and updates of the rules, regulations, and safety of SD. Given all the potential of diving combined with specific techniques for research, monitoring, and marine and limnic science in Brazil, we aim to understand the evolution of scientific diving teaching and to outline perspectives in the country, as it is crucial for the training of qualified scientists capable of performing these underwater tasks. Finally, we present future plans for the development of this activity in Brazil from the point of view of research and the labor market.

https://doi.org/10.1590/2675-2824071.23036tsl

14.

CYP2C19 metabolic estrogen phenotypes and endometriosis risk in Brazilian women CYPC CYP C CYP2C1 CYP2C
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Perini, Jamila Alessandra

; Machado, Daniel Escorsim

; Cardoso, Jéssica Vilarinho

; Fernandes, Vanessa Camara

; Struchiner, Claudio José

; Suarez-Kurtz, Guilherme

Clinics

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2023, Volume 78 elocation 100176

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1016/j.clinsp.2023.100176

15.

Medical research: Are e-Sports really sports? research eSports e Sports sports
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Scorza, Fulvio A.

; Fiorini, Ana C.

; Lima, Camila C. de

; Camilo, Nilton

; Magro, Eliana P.

; Guimarães, Liliane

; Pavanelli, Claudio

; Finsterer, Josef

; Almeida, Antonio-Carlos G. de

; Fonseca, Marcelo C.M.

; Fujita, Reginado R.

; Barros, Turibio L. de

; Scorza, Miguel M.C.

; Moret, Marcelo A.

; Teixeira-Machado, Lavínia

; Arida, Ricardo M.

Clinics

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2023, Volume 78 elocation 100190

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1016/j.clinsp.2023.100190

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