Pesquisa | SciELO

ABSTRACT BACKGROUND: Specific types of violence such as intimate partner sexual violence and intimate partner homicide occur more frequently in rural areas. OBJECTIVE: This study aimed to systematically review the literature on the knowledge and attitudes of rural healthcare providers regarding cases of domestic violence against women. DESIGN AND SETTING: Systematic review developed at Universidade Federal de Uberlândia. METHODS: We conducted an electronic search of six databases, which only included observational studies, regardless of the year, language, or country of publication, except for studies that used secondary data and were exclusively qualitative. Two reviewers performed the selection, data extraction, and risk of bias assessment using a specific Joanna Briggs Institute tool. RESULTS: Six studies met the inclusion criteria. All the studies had a low risk of bias. Approximately 38% of these professionals identified injuries caused by violence in patients. When asked about knowing the correct attitude to take in cases of confirmed violence, between 12% and 64% of rural healthcare providers answered positively; most of them would refer to specialized institutions and promote victim empowerment and counseling. The number of professionals with an educational background in the field ranged from 16% to 98%. CONCLUSIONS: The evident disparity across studies shows that some professionals have suboptimal knowledge and require training to adopt the correct attitude when identifying female victims of domestic violence in clinical practice. SYSTEMATIC REVIEW REGISTRATION: This systematic review was registered in the Open Science Framework Database under the registration http://doi.org/10.17605/OSF.IO/B7Q6S.

https://doi.org/10.1590/1516-3180.2022.0682.r1.180723

Accuracy of intrapartum cardiotocography in identifying fetal acidemia by umbilical cord blood analysis in low-risk pregnancies
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Tomich, Michaela Franco

; Leoni, Renato Silva

; Meireles, Pedro Teixeira

; Petrini, Caetano Galvão

; Araujo Júnior, Edward

; Peixoto, Alberto Borges

Revista da Associação Médica Brasileira

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2023, Volume 69 Nº 6 elocation e20221182

Resumo: En | Texto: En | PDF: En

SUMMARY OBJECTIVE: The aim of this study was to evaluate the accuracy of intrapartum cardiotocography in identifying fetal acidemia by umbilical cord blood analysis in low-risk pregnancies. METHODS: This is a retrospective cohort study of low-risk singleton pregnancies in labor after performing intrapartum cardiotocography categories I, II, and III. The presence of fetal acidemia at birth was identified by analyzing the pH of umbilical cord arterial blood (pH<7.1). RESULTS: No significant effect of the cardiotocography category on the arterial (p=0.543) and venous (p=0.770) pH of umbilical cord blood was observed. No significant association was observed between the cardiotocography category and the presence of fetal acidemia (p=0.706), 1-min Apgar score <7 (p=0.260), hospitalization in the neonatal intensive care unit (p=0.605), newborn death within the first 48 h, need for neonatal resuscitation (p=0.637), and adverse perinatal outcomes (p=0.373). Sensitivities of 62, 31, and 6.0%; positive predictive values of 11.0, 16.0, and 10.0%; and negative predictive values of 85, 89.0, and 87.0% were observed for cardiotocography categories I, II, and III, respectively. CONCLUSION: The three categories of intrapartum cardiotocography presented low sensitivities and high negative predictive values to identify fetal acidemia at birth in low-risk pregnancies.

https://doi.org/10.1590/1806-9282.20221182

Agroforestry system improves soil carbon and nitrogen stocks in depth after land-use changes in the Brazilian semi-arid region
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Tonucci, Rafael Gonçalves

; Vogado, Renato Falconeres

; Silva, Rodrigo Dias

; Pompeu, Roberto Cláudio Fernandes Franco

; Oda-Souza, Melissa

; Souza, Henrique Antunes de

Revista Brasileira de Ciência do Solo

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2023, Volume 47 elocation e0220124

Resumo: En | Texto: En | PDF: En

ABSTRACT Agroforestry systems have the potential to increase soil organic matter, with effects on soil carbon and nitrogen contents, but information on the application of these systems in semi-arid regions is still scarce. This study aimed to analyze soil carbon and nitrogen stocks in the conversion of native forest from the Caatinga Biome into integrated agriculture systems in the Brazilian semi-arid region. We evaluated the following management systems in the Haplic Inceptisol (Cambissolo Háplico eutrófico): (1) Intercropping area, cultivated with corn and Massai grass; (2) Caatinga (natural vegetation); (3) AFS10: agroforestry system with native woody forest rows occupying 33 % and agriculture occupying 66 % of the total area; and (4) AFS20: agroforestry system presenting inverse proportions of AFS10. The agroforestry systems were intercropped with sorghum or millet, pigeon pea and Massai grass. We collected disturbed and undisturbed soil samples at the layers of 0.00-0.10; 0.10-0.20; 0.20-0.40, 0.40-0.60 and 0.60-1.00 m for analysis of carbon (SOC), nitrogen (N), soil bulk density, and calculation of SOC and N stocks and C/N ratio, two years after the conversion of natural vegetation to the agricultural area (intercropping) and agroforestry system (AFS10 and AFS20). We applied principal component and cluster analysis to explore the data, and confidence interval to compare the means of accumulated SOC and N stocks up to 1 m soil depth. No differences exist for the properties analysed in superficial layers (0.00-0.10 and 0.10-0.20 m), regardless of land-use systems. AFS20 increase the SOC content and, consequently, SOC stock, in subsurface layers; on the other hand, intercropping increases N content and N stock. AFS20 presented higher accumulated SOC stocks up to 1.00 m (114.97 Mg ha-1). Agroforestry systems management is an alternative for increasing carbon sequestration under the conversion from Caatinga to agricultural areas.

https://doi.org/10.36783/18069657rbcs20220124

Accuracy of intrapartum cardiotocography in identifying acidemia at birth by umbilical cord blood gasometry in high-risk pregnancies
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Leoni, Renato Silva

; Tomich, Michaela Franco

; Meireles, Pedro Teixeira

; Petrini, Caetano Galvão

; Araujo Júnior, Edward

; Peixoto, Alberto Borges

Revista da Associação Médica Brasileira

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2023, Volume 69 Nº 11 elocation e20230511

Resumo: En | Texto: En | PDF: En

SUMMARY OBJECTIVE: The aim of this study was to evaluate the accuracy of intrapartum cardiotocography in identifying acidemia at birth by umbilical cord blood gasometry in high-risk pregnancies. METHODS: This was a retrospective cohort study of singleton high-risk parturients using intrapartum cardiotocography categories I, II, and III. The presence of fetal acidemia at birth was identified by the analysis of umbilical cord arterial blood pH (<7.1). Associations between variables were determined using the chi-square test and Kruskal-Wallis tests. RESULTS: We included 105 cases of cardiotocography category I, 20 cases of cardiotocography category II, and 10 cases of cardiotocography category III. cardiotocography category III had a higher prevalence of cesarean sections compared to cardiotocography category I (90.0 vs. 42.9%, p<0.006). Venous pH was higher in patients with cardiotocography category I compared to cardiotocography category III (7.32 vs. 7.23, p=0.036). Prevalence of neonatal intensive care unit (NICU) admission was lower in neonates of patients with cardiotocography category I compared to cardiotocography category III (3.8 vs. 30.0%, p=0.014). Prevalence of composite adverse outcomes was lower in neonates of patients with cardiotocography category I compared to cardiotocography category II (9.5 vs. 30.0%, p=0.022) and cardiotocography category III (9.5 vs. 60.0%, p=0.0004). cardiotocography categories II and III had low sensitivity (0.05 and 0.00, respectively) and high negative predictive value (NPV) (0.84 and 0.91, respectively) for identifying fetal acidemia at birth. The three categories of intrapartum cardiotocography showed high specificities (96.0, 99.0, and 99.0%, respectively). CONCLUSION: All three categories of intrapartum cardiotocography showed low sensitivity and high specificity for identifying acidemia at birth.

https://doi.org/10.1590/1806-9282.20230511

Associations of SARS-CoV-2 cycle threshold values with age, gender, sample collection setting, and pandemic period
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Franco-Miraglia, Fernando

; Martins-Freitas, Beatriz

; Doi, André Mario

; Santana, Rubia Anita Ferraz

; Pinho, João Renato Rebello

; Avelino-Silva, Vivian I.

Revista do Instituto de Medicina Tropical de São Paulo

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2023, Volume 65 elocation e53

Resumo: En | Texto: En | PDF: En

ABSTRACT Cycle threshold (Ct) values in COVID-19 reverse-transcription polymerase chain reaction (RT-PCR) tests estimate the viral load in biological samples. Studies have investigated variables associated with SARS-CoV-2 viral load, aiming to identify factors associated with higher transmissibility. Using the results from tests performed between May/2020-July/2022 obtained from the database of a referent hospital in Sao Paulo, Brazil, we investigated associations between Ct values and patient’s age, gender, sample collection setting and pandemic period according to the predominant SARS-CoV-2 variant locally. We also examined variations in Ct values, COVID-19 incidence, mortality, and vaccination coverage over time. The study sample included 42,741 tests. Gender was not significantly associated with Ct values. Age, sample collection setting and the pandemic period were significantly associated with Ct values even after adjustment to the multivariable model. Results showed lower Ct values in older groups, during the Gamma and Delta periods, and in samples collected in emergency units; and higher Ct values in children under 10 years old, home-based tests, during the Omicron period. We found evidence of a linear trend in the association between age and Ct values, with Ct values decreasing as age increases. We found no clear temporal associations between Ct values and local indicators of COVID-19 incidence, mortality, or vaccination between February/2020-November/2022. Our findings suggest that SARS-CoV-2 Ct values, a proxy for viral load and transmissibility, can be influenced by demographic and epidemiological variables.

https://doi.org/10.1590/s1678-9946202365053

Insights into Antarctic microbiomes: diversity patterns for terrestrial and marine habitats microbiomes
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BENDIA, AMANDA G.

; MOREIRA, JULIO CEZAR F.

; FERREIRA, JULIANA C.N.

; ROMANO, RENATO G.

; FERREIRA, IVAN G.C.

; FRANCO, DIEGO C.

; EVANGELISTA, HEITOR

; MONTONE, ROSALINDA C.

; PELLIZARI, VIVIAN HELENA

Anais da Academia Brasileira de Ciências

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2023, Volume 95 Supl. 3 elocation e20211442

Resumo: En | Texto: En | PDF: En

Abstract Microorganisms in Antarctica are recognized for having crucial roles in ecosystems functioning and biogeochemical cycles. To explore the diversity and composition of microbial communities through different terrestrial and marine Antarctic habitats, we analyze 16S rRNA sequence datasets from fumarole and marine sediments, soil, snow and seawater environments. We obtained measures of alpha- and beta-diversities, as well as we have identified the core microbiome and the indicator microbial taxa of a particular habitat. Our results showed a unique microbial community structure according to each habitat, including specific taxa composing each microbiome. Marine sediments harbored the highest microbial diversity among the analyzed habitats. In the fumarole sediments, the core microbiome was composed mainly of thermophiles and hyperthermophilic Archaea, while in the majority of soil samples Archaea was absent. In the seawater samples, the core microbiome was mainly composed by cultured and uncultured orders usually identified on Antarctic pelagic ecosystems. Snow samples exhibited common taxa previously described for habitats of the Antarctic Peninsula, which suggests long-distance dispersal processes occurring from the Peninsula to the Continent. This study contributes as a baseline for further efforts on evaluating the microbial responses to environmental conditions and future changes. cycles S environments alpha betadiversities, betadiversities beta diversities, diversities beta-diversities habitat absent longdistance long distance Continent changes

https://doi.org/10.1590/0001-3765202320211442

Effectiveness of Telemedicine in Reducing Hospitalizations in Patients Discharged from the Hospital Due to Heart Failure: A Randomized Clinical Trial Protocol
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Ribeiro, Edmar Geraldo

; Brant, Luisa

; Rezende, Lilian Cristina

; Teixeira, Renato Azeredo

; Parreiras, Laura Carvalho

; Franco, Tulio Batista

; Ribeiro, Antônio

; Malta, Deborah

International Journal of Cardiovascular Sciences

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Out 2022, Volume 35 Nº 5 Páginas 635 - 642

Resumo: En | Texto: En | PDF: En

Abstract Fundament: Telemedicine for follow-up in heart failure (HF) patients is effective in reducing hospitalizations, total and cardiovascular mortality. However, few studies were conducted in low and middle income, where lower access to technology and illiteracy could impact the results. Objective: To assess the effectiveness of associating telemedicine strategies, when compared to usual care, in reducing hospitalizations related to HF in patients discharged from the hospital due to HF. Methods: Controlled, randomized, multicenter, parallel-arm clinical trial, with an allocation ratio of 1:1, blinded to outcome evaluation, in which 340 patients who were discharged from public hospitals in Belo Horizonte due to HF will be randomized. Patients will be followed for 6 months and the intervention group will receive, in addition to the usual care, Structured Telephone Support (STS) from a nurse, a doctor, and an educational program. Counseling will be according to a clinical decision tree. The level of significance in the statistical analysis will be 5%. Expected results: Reduction in the number of hospital readmissions and/or in hospitalization time, in addition to developing a software with a clinical decision tree for remote follow-up and patient education about HF adapted to local culture. Conclusions: The intention of this study is to develop a telemedicine strategy and assess whether or not, in addition to the usual care, it is effective in reducing hospitalizations and mortality from HF. If effective, the aforementioned strategy could reduce costs and hospital needs in the Unified Health System (SUS, in Portuguese) for patients with HF. These results will be even more relevant considering the pandemic of COVID-19.

https://doi.org/10.36660/ijcs.20210131

É possível pensar em uma nova política editorial para as Revistas na área de História?
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Slemian, Andréa

; Franco, Renato

Revista Brasileira de História

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Set 2022, Volume 42 Nº 91 Páginas 7 - 14

Resumo: Pt | Texto: Pt | PDF: Pt

https://doi.org/10.1590/1806-93472022v42n91-02

Hemoglobin S identification in blood donors: A cross section of prevalence
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Kroger, Fernanda Lima

; Ernesto, Ianka Cristina

; Silva, Marina Schuffner

; Santos, Olivia Franco dos

; Medeiros, Renato Lourenço de

; Rodrigues, Daniela de Oliveira Werneck

Hematology, Transfusion and Cell Therapy

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Set 2022, Volume 44 Nº 3 Páginas 336 - 340

Resumo: En | Texto: En | PDF: En

ABSTRACT Introduction: In Brazil, the sickle cell trait (SCT) has an average prevalence of 4% in the general population and 6-10% among Afro-descendants. Although SCT is highly prevalent, a large segment of the population ignores their status. The Therapeutic Guidelines prohibit the transfusion of SCT red blood cells into patients with hemoglobin disorders or severe acidosis and newborns. Methods: This was a cross-sectional study with data from 37,310 blood donation candidates. The study included only eligible first-time donors qualified to be tested for the presence of hemoglobin S (HbS) at the Fundação Hemominas Juiz de Fora, Brazil. The variables studied were gender, skin color, age, type of donation, place of birth, blood type, result of the solubility test for hemoglobin S (HbST) and hemoglobin electrophoresis (HbEF). Statistical analysis was performed using the Q square test and the Kappa index of agreement for comparing biochemical methods. This project was approved by the National Research Ethics Committee. Results: The analysis of first-time donor data showed that 7166 were considered eligible. A total of 127 of the 7166 donors were carriers of SCT (1.77%). Among the blood donors, 73.23% were from the local area. The HbST and HbEF were found to be 100% in concordance. Sensitivity was not tested in the present study. Conclusions: The HbST is highly specific for identifying the HbS, but sensitivity was not tested in this study. The screening of blood donors for abnormal hemoglobins is useful, helping to detect and counsel heterozygous people. The study seeks to identify the prevalence of SCT in a region of Brazil.

https://doi.org/10.1016/j.htct.2020.11.009

10.

Impact of the COVID-19 pandemic on hospital admissions for cardiovascular diseases in a large Brazilian urban center
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Ribeiro, Edmar Geraldo

; Pinheiro, Pedro Cisalpino

; Nascimento, Bruno Ramos

; Cacique, João Pedro Pereira

; Teixeira, Renato Azeredo

; Nascimento, Jamil de Souza

; Franco, Tulio Batista

; Brant, Luisa Campos Caldeira

; Malta, Deborah Carvalho

Revista da Sociedade Brasileira de Medicina Tropical

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2022, Volume 55 Supl. 1 elocation e0264-2021

Resumo: En | Texto: En | PDF: En

Abstract INTRODUCTION: The COVID-19 pandemic has had a great impact on the behavior of individuals and the organization of health systems. This study analyzed the COVID-19 pandemic’s effect on public hospitalizations for cardiovascular diseases (CVD) in a large city in Brazil, Belo Horizonte, MG, with approximately 2.5 million inhabitants. METHODS: In a time-series analysis, this study used administrative data from the national “Hospital Information System” from 2010 to February 2020 to estimate the expected number of hospitalizations for CVD by month during the COVID-19 pandemic in Belo Horizonte in 2020 using the Auto-Regressive Integrated Moving Average model. For CVD, this study compared the expected number of hospital admissions, intensive care use, deaths during hospitalization, and mean length of stay with the observed number during the period. RESULTS: There were 6,517 hospitalizations for CVD from March to December 2020, a decrease of 16.3% (95% CI: 4.7-25.3) compared to the projected. The number of intensive care hospitalizations for CVD fell 24.1% (95% CI 13-32.7). The number of deaths also decreased (17.4% [80% CI: 0 - 0.30]), along with the reduction in hospitalizations, as did the length of stay for CVD hospitalizations. These reductions, however, were not significant. CONCLUSIONS: Hospitalizations for CVD were 16.3% lower than expected in a large Brazilian city, possibly due to the fear of getting infected or going to hospitals. Public campaigns informing how to proceed in case of CVD show that prompt urgent attention is essential to mitigate the indirect effects of the pandemic on CVD.

https://doi.org/10.1590/0037-8682-0264-2021

11.

SURFING ON PHYSICAL EDUCATION CURRICULUM AND THE IMPACT ON STUDENT’S WELL-BEING
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Silva, Bruno

; Cruz, Gonçalo

; Bentes, Renato

; Lima, Ricardo Franco

Journal of Physical Education

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2022, Volume 33 elocation e3317

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO As aulas de Educação Física representam uma oportunidade única de desenvolver competências motoras, habilidades esportivas e promover uma vida saudável. A prática esportiva no meio aquático, fornecem um local alternativo de alta qualidade para experiências educacionais ao ar livre. O surfe é um desporto aquático praticado ao ar livre, que se realiza em ambiente natural, revelando-se como uma importante forma de aprendizagem e terapia. O objetivo desta pesquisa foi analisar quantitativa e qualitativamente a importância do surfe nas aulas de Educação Física (EF) como suporte ao bem-estar de crianças e adolescentes. Um total de 190 alunos (80 meninas) participaram deste estudo e foram inicialmente avaliados antes e após 6 semanas de prática de surfe, como parte de um currículo de EF, quanto aos impactos no bem-estar e na socialização. Analisando os dois momentos, as questões mais valorizadas foram Q5 (4,39 ± 0,827; 4,52 ± 0,791) e Q14 (4,60 ± 0,716; 4,47 ± 0,808). A análise fatorial exploratória resultou em 3 categorias (Expectativas Individuais; Autoconfiança; Socialização no Surfe), que explicam 62,79% da variância total. O fator Expectativa Individual foi o mais significativo e a Autoconfiança teve o aumento mais significativo. O surfe no currículo de EF pode ser considerado uma atividade segura, um importante mediador para fazer novos amigos e fazer parte de um grupo, com importantes efeitos de curto prazo na autoconfiança, principalmente em adolescentes.

ABSTRACT Physical Educations classes represent a unique opportunity to develop motor competence, sports skills and foster healthy life. Blue spaces environments provide an alternative location for high-quality outdoor educational experiences. Throughout, surfing is an aquatic outdoor sport, that takes place in the natural setting, proved as an important learning and therapeutic approach. The aim of this research was to analyze the importance of surfing in Physical Education (PE) classes as a support of children and adolescent’s well-being. A total of 190 students (80 girls) participated in this study and were assessed at baseline and after 6 weeks of surfing practice as part of a PE curriculum, regarding the impacts on well-being and socialization. Analyzing the two moments, the most valued questions were Q5(4.39±0.827; 4.52±0.791) and Q14(4.60±0.716; 4.47±0.808). The exploratory factor analysis results in 3 categories (Individual Expectations; Self-Confidence; Socialization in Surfing), which explain 62.79% of the total variance. The factor Individual Expectation was the most significant and Self-Confidence had the most significant increase. Surfing as part of the PE curriculum can be considered a safe activity, an important mediator for making new friends and being part of a group with important short-term effects on self-confidence, especially in adolescents.

https://doi.org/10.4025/jphyseduc.v33i1.3317

12.

Gas exchanges, chemical composition and productive characteristics of tropical grasses deferred I: cultivars BRS Massai and BRS Tamani
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FONTINELE, Renato Gomes

; ARAÚJO, Ricardo Alves de

; CÂNDIDO, Magno José Duarte

; ROGÉRIO, Marcos Cláudio Pinheiro

; COSTA, Clésio dos Santos

; SOUZA, Henrique Antunes de

; FURTADO, Rafael Nogueira

; POMPEU, Roberto Cláudio Fernandes Franco

Revista Brasileira de Saúde e Produção Animal

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2022, Volume 23 elocation e202220200062

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivou-se avaliar os parâmetros fisiológicos, as características produtivas, estruturais e composição química de Megathyrsus maximus (syn. Panicum maximum) cultivares BRS Massai e BRS Tamani submetidas à diferentes períodos de diferimento e momentos de utilização. Utilizou-se o delineamento de blocos completos casualizados, em esquema fatorial 2 x 2 x 3, sendo duas cultivares de gramíneas (capim-massai e capim-tamani), dois períodos de diferimento (período chuvoso e transição chuvoso-seco) e três tempos de vedação (40, 80 e 120 dias). Ambas as cultivares tiveram maior taxa de transpiração foliar quando utilizadas aos 40 dias de diferimento (0,63 μmol/m2/s). Observou-se que a cultivar BRS Massai apresentou a maior taxa fotossintética (1,10 μmol/m²/s), taxa de produção e acúmulo de forragem quando utilizada aos 40 dias de diferimento (P<0,05). Por outo lado, houve maior eficiência no uso da água durante o período de transição nos pastos vedados por 80 e 120 dias (64,60 e 62,30 kg de MS/ha/mm, respectivamente). Observou-se redução (P<0,05) dos nutrientes digestíveis totais (NDT) e proteína bruta (PB) com o aumento no tempo de vedação das pastagens. De modo geral o diferimento no período de transição possibilita a utilização da forragem sem maiores perdas produtivas e nutritivas até os 80 dias de vedação para a cultivar BRS Tamani e até os 40 dias para a BRS Massai.

ABSTRACT This study aimed to evaluate the physiological parameters, the productive characteristics, structural and chemical composition of Megathyrsus maximus (syn. Panicum maximum) cultivars BRS Massai and BRS Tamani submitted to different periods of deferment and moments of use. The experimental design was randomized complete block design in a factorial scheme 2 x 2 x 3, being two grass cultivars (Massai grass and Tamani grass), two deferment periods (rainy season and dry-rainy transition) and three sealing times (40, 80 and 120 days). Both cultivars had higher leaf transpiration rate when used for 40 days of deferment (0.63 μmol/m2/s). It was observed that the cultivar BRS Massai presented higher photosynthetic rate (P<0.05) to 40 days of deferment (1.10 μmol/m2/s), higher rate of production and forage accumulation when used for 40 days. On another side, there was a greater efficiency in the use of water during the period of transition in the pastures sealed for 80 and 120 days (64.60 and 62.30 kg DM/ha/mm, respectively). A reduction (P<0.05) of total digestible nutrients (TDN) and crude protein (CP) was observed with the increase in pasture sealing time. In general, the deferment in the transition period allows the use of forage without greater productive and nutrient losses up to 80 days of sealing for the cultivar BRS Tamani and up to 40 days for BRS Massai.

https://doi.org/10.1590/s1519-9940202220200062

13.

Cannabinoids in Neurology - Position paper from Scientific Departments from Brazilian Academy of Neurology
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BRUCKI, Sonia Maria Dozzi

; ADONI, Tarso

; ALMEIDA, Carlos Mauricio Oliveira

; ANDRADE, Daniel Ciampi de

; ANGHINAH, Renato

; BARBOSA, Luciana Mendonça

; BAZAN, Rodrigo

; CARVALHO, Alzira Alves de Siqueira

; CARVALHO, William

; CHRISTO, Paulo Pereira

; COLETTA, Marcus Della

; CONFORTO, Adriana Bastos

; CORREA-NETO, Ylmar

; ENGELHARDT, Eliasz

; FRANÇA JUNIOR, Marcondes Cavalcante

; FRANCO, Clelia

; VON GLEHN, Felipe

; GOMES, Helio Rodrigues

; HOULY, Caroline Gomes de Barros

; KAUP, Alexandre Ottoni

; KOWACS, Fernando

; KANASHIRO, Aline

; LOPES, Victor Gonçalves

; MAIA, Débora

; MANREZA, Maria

; MARTINEZ, Alberto Rolim Muro

; MARTINEZ, Sandra Cristina Gonçalves

; NADER, Saulo Nardy

; NEVES, Luciana de Oliveira

; OKAMOTO, Ivan Hideyo

; OLIVEIRA, Rogério Adas Ayres de

; PEIXOTO, Fabiano de Melo

; PEREIRA, Cristiana Borges

; SABA, Roberta Arb

; SAMPAIO, Leticia Pereira de Brito

; SCHILLING, Lucas Porcello

; SILVA, Marcus Tulius Teixeira

; SILVA, Emanuelle Roberta

; SMID, Jerusa

; SOARES, Cristiane Nascimento

; SOBREIRA-NETO, Manoel

; SOUSA, Nise Alessandra de Carvalho

; SOUZA, Leonardo Cruz de

; TEIVE, Hélio Afonso Ghizoni

; TERRA, Vera Cristina

; VALE, Matheus

; VIEIRA, Vitor Mendes Grise

; ZANOTELI, Edmar

; PRADO, Gilmar

Arquivos de Neuro-Psiquiatria

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Abr 2021, Volume 79 Nº 4 Páginas 354 - 369

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Os canabinoides compreendem os endocanabinoides, fitocanabinoides e os canabinoides sintéticos e desempenham ações no sistema nervoso central e periférico. Uma quantidade enorme de publicações tem sido lançada nos últimos anos, embora a cannabis seja conhecida por milênios. Os Departamentos Científicos da Academia Brasileira de Neurologia descreveram as evidências do uso médico em suas áreas. A literatura está em constantes mudanças e possíveis novas evidências podem surgir nos próximos dias ou meses. A prescrição dessas substâncias deve ser discutida com os pacientes e suas famílias, com conhecimento sobre eventos adversos e sua eficácia.

ABSTRACT Cannabinoids comprehend endocannabinoids, phytocannabinoids, and synthetic cannabinoids, with actions both in the central and peripherical nervous systems. A considerable amount of publications have been made in recent years, although cannabis has been known for over a thousand years. Scientific Departments from the Brazilian Academy of Neurology described evidence for medical use in their areas. Literature is constantly changing, and possible new evidence can emerge in the next days or months. Prescription of these substances must be discussed with patients and their families, with knowledge about adverse events and their efficacy.

https://doi.org/10.1590/0004-282x-anp-2020-0432 1049 downloads

14.

Práticas de ressuscitação volêmica em unidades de terapia intensiva brasileiras: uma análise secundária do estudo Fluid-TRIPS
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Freitas, Flavio Geraldo Rezende de

; Hammond, Naomi

; Li, Yang

; Azevedo, Luciano Cesar Pontes de

; Cavalcanti, Alexandre Biasi

; Taniguchi, Leandro

; Gobatto, André

; Japiassú, André Miguel

; Bafi, Antonio Tonete

; Mazza, Bruno Franco

; Noritomi, Danilo Teixeira

; Dal-Pizzol, Felipe

; Bozza, Fernando

; Salluh, Jorge Ibrahin Figueira

; Westphal, Glauco Adrieno

; Soares, Márcio

; Assunção, Murillo Santucci César de

; Lisboa, Thiago

; Lobo, Suzana Margarete Ajeje

; Barbosa, Achilles Rohlfs

; Ventura, Adriana Fonseca

; Souza, Ailson Faria de

; Silva, Alexandre Francisco

; Toledo, Alexandre

; Reis, Aline

; Cembranel, Allan

; Rea Neto, Alvaro

; Gut, Ana Lúcia

; Justo, Ana Patricia Pierre

; Santos, Ana Paula

; Albuquerque, André Campos D. de

; Scazufka, André

; Rodrigues, Antonio Babo

; Fernandino, Bruno Bonaccorsi

; Silva, Bruno Goncalves

; Vidal, Bruno Sarno

; Pinheiro, Bruno Valle

; Pinto, Bruno Vilela Costa

; Feijo, Carlos Augusto Ramos

; Abreu Filho, Carlos de

; Bosso, Carlos Eduardo da Costa Nunes

; Moreira, Carlos Eduardo Nassif

; Ramos, Carlos Henrique Ferreira

; Tavares, Carmen

; Arantes, Cidamaiá

; Grion, Cintia

; Mendes, Ciro Leite

; Kmohan, Claudio

; Piras, Claudio

; Castro, Cristine Pilati Pileggi

; Lins, Cyntia

; Beraldo, Daniel

; Fontes, Daniel

; Boni, Daniela

; Castiglioni, Débora

; Paisani, Denise de Moraes

; Pedroso, Durval Ferreira Fonseca

; Mattos, Ederson Roberto

; Brito Sobrinho, Edgar de

; Troncoso, Edgar M. V.

; Rodrigues Filho, Edison Moraes

; Nogueira, Eduardo Enrico Ferrari

; Ferreira, Eduardo Leme

; Pacheco, Eduardo Souza

; Jodar, Euzebio

; Ferreira, Evandro L. A.

; Araujo, Fabiana Fernandes de

; Trevisol, Fabiana Schuelter

; Amorim, Fábio Ferreira

; Giannini, Fabio Poianas

; Santos, Fabrício Primitivo Matos

; Buarque, Fátima

; Lima, Felipe Gallego

; Costa, Fernando Antonio Alvares da

; Sad, Fernando Cesar dos Anjos

; Aranha, Fernando G.

; Ganem, Fernando

; Callil, Flavio

; Costa Filho, Francisco Flávio

; Dall´Arto, Frederico Toledo Campo

; Moreno, Geovani

; Friedman, Gilberto

; Moralez, Giulliana Martines

; Silva, Guilherme Abdalla da

; Costa, Guilherme

; Cavalcanti, Guilherme Silva

; Betônico, Gustavo Navarro

; Reis, Hélder

; Araujo, Helia Beatriz N.

; Hortiz Júnior, Helio Anjos

; Guimaraes, Helio Penna

; Urbano, Hugo

; Maia, Israel

; Santiago Filho, Ivan Lopes

; Farhat Júnior, Jamil

; Alvarez, Janu Rangel

; Passos, Joel Tavares

; Paranhos, Jorge Eduardo da Rocha

; Marques, José Aurelio

; Moreira Filho, José Gonçalves

; Andrade, Jose Neto

; Sobrinho, José Onofre de C

; Bezerra, Jose Terceiro de Paiva

; Alves, Juliana Apolônio

; Ferreira, Juliana

; Gomes, Jussara

; Sato, Karina Midori

; Gerent, Karine

; Teixeira, Kathia Margarida Costa

; Conde, Katia Aparecida Pessoa

; Martins, Laércia Ferreira

; Figueirêdo, Lanese

; Rezegue, Leila

; Tcherniacovsk, Leonardo

; Ferraz, Leone Oliveira

; Cavalcante, Liane

; Rabelo, Ligia

; Miilher, Lilian

; Garcia, Lisiane

; Tannous, Luana

; Hajjar, Ludhmila Abrahão

; Paciência, Luís Eduardo Miranda

; Cruz Neto, Luiz Monteiro da

; Bley, Macia Valeria

; Sousa, Marcelo Ferreira

; Puga, Marcelo Lourencini

; Romano, Marcelo Luz Pereira

; Nobrega, Marciano

; Arbex, Marcio

; Rodrigues, Márcio Leite

; Guerreiro, Márcio Osório

; Rocha, Marcone

; Alves, Maria Angela Pangoni

; Rosa, Maria Doroti

; Dias, Mariza D’Agostino

; Martins, Miquéias

; Oliveira, Mirella de

; Moretti, Miriane Melo Silveira

; Matsui, Mirna

; Messender, Octavio

; Santarém, Orlando Luís de Andrade

; Silveira, Patricio Júnior Henrique da

; Vassallo, Paula Frizera

; Antoniazzi, Paulo

; Gottardo, Paulo César

; Correia, Paulo

; Ferreira, Paulo

; Torres, Paulo

; Silva, Pedro Gabrile M. de Barros e

; Foernges, Rafael

; Gomes, Rafael

; Moraes, Rafael

; Nonato filho, Raimundo

; Borba, Renato Luis

; Gomes, Renato V

; Cordioli, Ricardo

; Lima, Ricardo

; López, Ricardo Pérez

; Gargioni, Ricardo Rath de Oliveira

; Rosenblat, Richard

; Souza, Roberta Machado de

; Almeida, Roberto

; Narciso, Roberto Camargo

; Marco, Roberto

; waltrick, Roberto

; Biondi, Rodrigo

; Figueiredo, Rodrigo

; Dutra, Rodrigo Santana

; Batista, Roseane

; Felipe, Rouge

; Franco, Rubens Sergio da Silva

; Houly, Sandra

; Faria, Sara Socorro

; Pinto, Sergio Felix

; Luzzi, Sergio

; Sant’ana, Sergio

; Fernandes, Sergio Sonego

; Yamada, Sérgio

; Zajac, Sérgio

; Vaz, Sidiner Mesquita

; Bezerra, Silvia Aparecida Bezerra

; Farhat, Tatiana Bueno Tardivo

; Santos, Thiago Martins

; Smith, Tiago

; Silva, Ulysses V. A.

; Damasceno, Valnei Bento

; Nobre, Vandack

; Dantas, Vicente Cés de Souza

; Irineu, Vivian Menezes

; Bogado, Viviane

; Nedel, Wagner

; Campos Filho, Walther

; Dantas, Weidson

; Viana, William

; Oliveira Filho, Wilson de

; Delgadinho, Wilson Martins

; Finfer, Simon

; Machado, Flavia Ribeiro

Revista Brasileira de Terapia Intensiva

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Abr 2021, Volume 33 Nº 2 Páginas 206 - 218

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Descrever as práticas de ressuscitação volêmica em unidades de terapia intensiva brasileiras e compará-las com as de outros países participantes do estudo Fluid-TRIPS. Métodos: Este foi um estudo observacional transversal, prospectivo e internacional, de uma amostra de conveniência de unidades de terapia intensiva de 27 países (inclusive o Brasil), com utilização da base de dados Fluid-TRIPS compilada em 2014. Descrevemos os padrões de ressuscitação volêmica utilizados no Brasil em comparação com os de outros países e identificamos os fatores associados com a escolha dos fluidos. Resultados: No dia do estudo, foram incluídos 3.214 pacientes do Brasil e 3.493 pacientes de outros países, dos quais, respectivamente, 16,1% e 26,8% (p < 0,001) receberam fluidos. A principal indicação para ressuscitação volêmica foi comprometimento da perfusão e/ou baixo débito cardíaco (Brasil 71,7% versus outros países 56,4%; p < 0,001). No Brasil, a percentagem de pacientes que receberam soluções cristaloides foi mais elevada (97,7% versus 76,8%; p < 0,001), e solução de cloreto de sódio a 0,9% foi o cristaloide mais comumente utilizado (62,5% versus 27,1%; p < 0,001). A análise multivariada sugeriu que os níveis de albumina se associaram com o uso tanto de cristaloides quanto de coloides, enquanto o tipo de prescritor dos fluidos se associou apenas com o uso de cristaloides. Conclusão: Nossos resultados sugerem que cristaloides são usados mais frequentemente do que coloides para ressuscitação no Brasil, e essa discrepância, em termos de frequências, é mais elevada do que em outros países. A solução de cloreto de sódio 0,9% foi o cristaloide mais frequentemente prescrito. Os níveis de albumina sérica e o tipo de prescritor de fluidos foram os fatores associados com a escolha de cristaloides ou coloides para a prescrição de fluidos.

Abstract Objective: To describe fluid resuscitation practices in Brazilian intensive care units and to compare them with those of other countries participating in the Fluid-TRIPS. Methods: This was a prospective, international, cross-sectional, observational study in a convenience sample of intensive care units in 27 countries (including Brazil) using the Fluid-TRIPS database compiled in 2014. We described the patterns of fluid resuscitation use in Brazil compared with those in other countries and identified the factors associated with fluid choice. Results: On the study day, 3,214 patients in Brazil and 3,493 patients in other countries were included, of whom 16.1% and 26.8% (p < 0.001) received fluids, respectively. The main indication for fluid resuscitation was impaired perfusion and/or low cardiac output (Brazil: 71.7% versus other countries: 56.4%, p < 0.001). In Brazil, the percentage of patients receiving crystalloid solutions was higher (97.7% versus 76.8%, p < 0.001), and 0.9% sodium chloride was the most commonly used crystalloid (62.5% versus 27.1%, p < 0.001). The multivariable analysis suggested that the albumin levels were associated with the use of both crystalloids and colloids, whereas the type of fluid prescriber was associated with crystalloid use only. Conclusion: Our results suggest that crystalloids are more frequently used than colloids for fluid resuscitation in Brazil, and this discrepancy in frequencies is higher than that in other countries. Sodium chloride (0.9%) was the crystalloid most commonly prescribed. Serum albumin levels and the type of fluid prescriber were the factors associated with the choice of crystalloids or colloids for fluid resuscitation.

https://doi.org/10.5935/0103-507x.20210028 273 downloads

15.

[SciELO Preprints] - Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants
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Marquitti, Flavia Maria Darcie Coutinho, Renato Mendes Ferreira, Leonardo Souto Borges, Marcelo Eduardo Portella, Tatiana P Silva, Rafael Lopes Paixão da Canton, Otavio Poloni, Silas Franco, Caroline Coelho, Verônica Barberia, Lorena Bolle, Monica de Boing, Alexandra Crispim Donalisio , Maria Rita Boing, Antonio Fernando Silva, Antônio Augusto Moura da Prado, Paulo Inácio Veras, Maria Amélia de Sousa Mascena Kraenkel, Roberto

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Data de publicação: 2021-03-23

Resumo: En Pt

This letter discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain, called P1, more transmissible and with possible associated reinfection. Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, all of which found increased transmissibility of the P.1 variant, we propose some urgent actions: the establishment of genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests to sequencing; an immediate effort to identify reinfections associated with the new variant, updating its definition protocols; and studies on the efficacy of currently available vaccines in Brazil in respect to the new variant. We also propose the improvement of the Brazilian health surveillance system, which should be articulated with genomic surveillance, in order to respond more timely to future emergencies. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.

Esta carta discute a situação epidêmica da Covid-19 no Brasil frente aoaparecimento de uma nova linhagem, chamada P1, mais transmissível e compossível re-infecção associada. Tendo em vista o colapso do atendimentohospitalar em Manaus em janeiro de 2021 e os resultados de três preprintsrecentes, todos encontrando maior transmissibilidade da variante P.1, propomos algumas ações urgentes: o estabelecimento de uma vigilância genômica baseada em diagnóstico em múltiplos passos, iniciando com os testes do tipo RT-PCR até o sequenciamento; um esforço imediato na identificação de re-infecções associadas à nova variante, atualizando os seus protocolos de definição; e estudos sobre a eficácia das vacinas atualmente disponíveis no Brasil na vigência da nova variante. Propomos, ademais, o aprimoramento do sistema de vigilância em saúde brasileiro, que seja articulado com a vigilância genômica, de forma a responder mais oportunamente a emergências futuras. Chamamos os agentes públicos implicados na vigilância em saúde para que compartilhem dados e informações referentes à epidemia de forma clara, rápida e transparente. Finalmente propomos um maior engajamento na cooperação inter-institucional de todos os envolvidos na resposta e produção de conhecimento sobre a pandemia em nosso país.

https://doi.org/10.1590/SciELOPreprints.2001

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