Abstract Background Coronavirus disease 2019 (COVID-19) is a viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although respiratory manifestations have received greater visibility during the pandemic caused by this virus, numerous neurological complaints related to coronavirus 2 infection have been documented in several countries. These records suggest that this pathogen presents neurotropism, and it can cause different neurological conditions of varying intensity. Objective To investigate the ability of coronavirus 2 to invade the central nervous system (CNS) and its neurological clinical outcomes. Methods The present study consists in a comprehensive literature review of the records available in the PubMed, SciELO, and Google Scholar databases. The descriptors COVID-19, brain and physiopathology, associated with the Boolean operator AND, were used in the search. Regarding the inclusion and exclusion criteria, we selected the papers published since 2020 with the highest number of citations. Results We selected 41 articles, most of them in English. The main clinical manifestation associated with COVID-19 patients was headache, but cases of anosmia, hyposmia, Guillain-Barré syndrome, and encephalopathies were also described with considerable frequency. Conclusion Coronavirus-2 presents neurotropism, and it can reach the CNS by hematogenous dissemination and by direct infection of the nerve endings. It causes brain injuries through several mechanisms, such as cytokine storm, microglial activation, and an increase in thrombotic factors.

Resumo Antecedentes A doença do coronavírus 2019 (coronavirus disease 2019, Covid-19, em inglês) é uma infecção viral provocada pelo coronavírus 2 da síndrome respiratória aguda grave (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, em inglês). Embora as manifestações respiratórias tenham recebido maior visibilidade ao longo da pandemia provocada por esse vírus, inúmeras queixas neurológicas relacionadas à infecção pelo coronavírus 2 foram documentadas em diversos países. Tais registros sugerem que esse patógeno apresenta neurotropismo, e é capaz de provocar quadros neurológicos diversos e de intensidade variáveis. Objetivo Investigar a capacidade de invasão do sistema nervoso central (SNC) pelo coronavírus 2 e seus principais desfechos clínicos neurológicos. Métodos O presente estudo consiste em uma ampla revisão de literatura a partir dos registros das bases de dados PubMed, SciELO e Google Acadêmico. Nesse contexto, os descritores COVID-19, cérebro e fisiopatologia, associados com o operador booleano AND, foram utilizados na busca. Quanto aos critérios de inclusão e exclusão, selecionou-se os trabalhos publicados a partir de 2020 com o maior número de citações. Resultados Foram selecionados 41 artigos, a maioria na língua inglesa. A principal manifestação clínica associada a pacientes acometidos pela COVID-19 foi a cefaleia, mas casos de anosmia, hiposmia, síndrome de Guillain-Barré e encefalopatias também foram descritos com frequência considerável. Conclusão O coronavírus 2 apresenta neurotropismo, e é capaz de alcançar o SNC por disseminação hematogênica e por infecção direta das terminações nervosas. Ele provoca injúria cerebral por meio de variados mecanismos, como tempestade de citocinas, ativação da micróglia e aumento dos fatores trombóticos.

ABSTRACT The São Francisco Valley region of Brazil is a leading exporter of mango fruits. Previous nutritional diagnosis can identify stresses, provide adjustments for nutritional limitations, and promote more efficient fertilization and nutrient management. This study aimed to compare the nutritional diagnosis of mango trees in the post-harvest and pre-flowering phases and to correlate them with productivity. Norms and indices of the Integrated System of Diagnosis and Recommendation (DRIS), as well as the Nutritional Balance Index and the Potential of Response to Fertilization were generated for each phenological phase of the mango trees. Optimal concentrations and ranges of nutrients were established, classified as deficient, balanced, or excessive, and subsequently compared to each other and to values recommended in the literature. The indices were correlated with the productivity of the orchards in each phenological phase of the mango trees. When comparing the DRIS norms of post-harvest and pre-flowering phenological phases, 55% of the averages differed. The sufficiency ranges of the post-harvest and pre-flowering phases were generally different from those referenced in the literature. Nutritional diagnoses for P, K, Ca, Mg, S, Zn, and Cl altered between phenological phases. The nutritional diagnosis performed in the post-harvest phase showed that nutritional imbalance affected productivity.

RESUMO A região do Vale do São Francisco no Brasil destaca-se na exportação de frutos de manga. O diagnóstico nutricional prévio pode identificar estresses, antecipar a correção de limitações nutricionais e promover um manejo nutricional da fertilização mais eficiente. O estudo objetivou comparar o diagnóstico nutricional em mangueiras nas fases de pós-colheita e pré-florescimento e correlacionar com a produtividade. Normas e índices do Sistema Integrado de Diagnose e Recomendação foram geradas para cada fase fenológica das mangueiras, bem como o Índice de Balanço Nutricional e o Potencial de Resposta a Adubação. Os teores e faixas ótimas de nutrientes foram estabelecidos e classificados em deficientes, equilibrados ou excessivos. Esses teores e faixas ótimas de nutrientes foram comparados entre si e com valores recomendados na literatura. Os índices foram correlacionados com a produtividade dos pomares em cada fase fenológica das mangueiras. Ao comparar as normas DRIS das fases fenológicas pós-colheita e pré-floração, 55% das médias diferiram. As faixas de suficiência das fases pós-colheita e pré-floração, em geral, foram diferentes das referenciadas na literatura. Os diagnósticos nutricionais para os nutrientes P, K, Ca, Mg, S, Zn e Cl diferiram entre as fases fenológicas. O diagnóstico nutricional realizado na fase de pós-colheita mostrou que o desequilíbrio nutricional afetou a produtividade.

ABSTRACT BACKGROUND: Weight regain in the postoperative period after bariatric surgery is directly related to the relapse of preoperative comorbidities and a negative impact on the patients’ biochemical profile. AIMS: To assess the metabolic impact of weight regain on preoperative comorbidities and on patients’ biochemical profiles, in order to show the impact of the complications on the metabolic outcomes of bariatric surgery. METHODS: A retrospective study was carried out with 75 women in the late postoperative period of bariatric surgery who presented pathological weight regain (≥20% of the maximum weight loss). Data of interest consisted of glycemic, lipid, and inflammatory profile measurements at three different moments of evaluation: preoperative period, at the weight nadir (minimum weight), and after weight regain. A multivariate analysis was performed. RESULTS: The mean age was 46.39±12.09 years. Preoperative body mass index was 40.10±4.11 kg/m2. There was an overall increase of 3.36 points in the mean body mass index between the nadir and after regain: from 26.30±3.9 kg/m2 to 29.66±4.66 kg/m2. The mean time to reach the nadir was 18±7.6 months, with an average percentage of excess weight loss of 91.08±11.8%. The median time for pathological weight regain was 48 months, and the mean regain amongst the sample was 8.85±5.65 kg. There was a significant correlation between pathological weight regain and levels of insulin (r=0.351; p<0.011), C-peptide (r=0.303; p<0.011), C-reactive protein (r=0.402; p<0.001), and vitamin D (r=-0.435; p<0.001), the last two being the most influenced by the percentage of weight regained. CONCLUSIONS: The pathological weight regain in the postoperative period of bariatric surgery results in losses in the patients’ metabolic and inflammatory profiles. However, the biochemical benefits are sustained up to the preoperative levels of the parameters analyzed.

RESUMO RACIONAL: Reganho de peso no pós-operatório de cirurgia bariátrica está diretamente relacionado à recidiva das comorbidades pré-operatórias e a um impacto negativo no perfil bioquímico desses pacientes. OBJETIVOS: avaliar o impacto metabólico do reganho de peso nas comorbidades pré-operatórias e no perfil bioquímico desses pacientes, a fim de mostrar o impacto das complicações nos desfechos metabólicos finais da cirurgia bariátrica. MÉTODOS: Estudo retrospectivo que analisou 75 mulheres no pós-operatório tardio de cirurgia bariátrica que apresentaram reganho patológico de peso (=20% do máximo de peso perdido). Foram coletados dados referentes às medidas dos perfis glicêmico, lipídico e inflamatório em três momentos distintos de avaliação: no pré-operatório, no nadir de peso (menor peso) e após o reganho ponderal. Foi realizada uma análise multivariada. RESULTADOS: A idade média foi 46.39±12.09 anos. IMC médio pré-operatório foi 40.10±4.11 kg/m2. Houve um aumento de 3,36 pontos no IMC médio entre o nadir e após reganho: de 26.30±3.9 Kg/m2 para 29.66±4.66 Kg/m2. O tempo médio para atingir o nadir foi de 18±7.6 meses, com uma %PEP de 91.08±11.8%. O tempo médio para o reganho patológico foi de 48 meses, e a média de reganho foi 8.85±5.65 kg. Houve correlação significativa entre o reganho patológico e os níveis de insulina (r=0.351; p<0.011), peptídeo C (r=0.303; p<0.011), proteína C reativa (r=0.402; p<0.001) e vitamina D (r=-0.435; p<0.001), sendo os dois últimos os mais influenciados pela porcentagem de reganho de peso. CONCLUSÕES: O reganho de peso patológico no pós-operatório de cirurgia bariátrica resulta em prejuízos ao perfil metabólico e inflamatório dos pacientes. No entanto, os benefícios bioquímicos perduram em relação aos níveis pré-operatórios dos parâmetros analisados

ABSTRACT Background: The long-term effects of schistosomiasis on the glomerulus may contribute to the development of chronic kidney disease. This study aimed to investigate baseline Schistosoma mansoni-Circulating Anodic Antigen (CAA) levels and their association with kidney biomarkers related to podocyte injury and inflammation in long-term follow-up after praziquantel (PZQ) treatment. Methods: Schistosoma infection was diagnosed by detecting CAA in urine using a quantitative assay based on lateral flow using luminescent up-converting phosphor reporter particles. A cutoff threshold of 0.1 pg/mL CAA was used to diagnose Schistosoma infection (baseline) in a low-prevalence area in Ceará, Northeast, Brazil. Two groups were included: CAA-positive and CAA-negative individuals, both of which received a single dose of PZQ at baseline. Urinary samples from 55 individuals were evaluated before (baseline) and at 1, 2, and 3 years after PZQ treatment. At all time points, kidney biomarkers were quantified in urine and adjusted for urinary creatinine levels. Results: CAA-positive patients had increased baseline albuminuria and proteinuria and showed greater associations between kidney biomarkers. CAA levels correlated only with Vascular Endothelial Growth Factor (VEGF) (podocyte injury) levels. Increasing trends were observed for malondialdehyde (oxidative stress), monocyte chemoattractant protein-1 (inflammation marker), and VEGF. In the follow-up analysis, no relevant differences were observed in kidney biomarkers between the groups and different periods. Conclusions: S. mansoni-infected individuals presented subclinical signs of glomerular damage that may reflect podocyte injury. However, no causal effect on long-term renal function was observed after PZQ treatment.

Abstract: Introduction: Medical Residency is identified as the best program for training physicians in specialties, developed in an in-service training setting for an extensive period, and understood as a space for constant education and teaching. The trainee doctor develops not only technical skills but also practices of responsible conduct. Objectives: To understand the professional training profile of preceptors of the Medical Residency Program in Anesthesiology, to verify the preceptors’ view of their educational practice developed in the Program, and to identify the pedagogical models used in the same environment. Methods: This is a cross-sectional, exploratory descriptive study, with a quantitative approach and analytical component, carried out from January 2017 to January 2018, in three public educational institutions that offer the Medical Residency Program in Anesthesiology in the city of Manaus - AM. Data were collected using an instrument containing sociodemographic information; a validated questionnaire (focusing on perception regarding preceptorship); plus a question about the adopted pedagogical model. Results: The study sample consisted mostly of female preceptors (60%) with medical residency as the highest level of their qualification (96.6%). A significant percentage (80%) reported not having pedagogical training to develop preceptorship. The traditional pedagogical model was the most commonly adopted in the teaching practice of preceptors. Conclusions: The importance of the situational diagnosis of preceptorship in the Medical Residency in Anesthesiology is shown, pointing out the need for teacher training for the development of the preceptor role, as well as it being given its due value, with the aim of achieving the best medical training.

Resumo: Introdução: A residência médica é identificada como o melhor programa de formação de médicos em especialidades, sendo desenvolvida em cenário de treinamento em serviço, de duração extensa, entendida como um espaço de educação e ensino constantes. Nela, o médico em formação desenvolve não unicamente habilidades técnicas, mas também práticas de conduta responsável. Objetivo: Este estudo teve como objetivos conhecer o perfil de formação profissional dos preceptores do Programa de Residência Médica em Anestesiologia, verificar a percepção deles sobre a sua prática educativa desenvolvida no programa e identificar os modelos pedagógicos utilizados no mesmo ambiente. Método: Trata-se de um estudo transversal, do tipo descritivo exploratório, com abordagem quantitativa e componente analítico, realizado no período de janeiro de 2017 a janeiro de 2018, em três instituições públicas de ensino que oferecem o Programa de Residência Médica em Anestesiologia na cidade de Manaus, no Amazonas. Os dados foram coletados por meio de um instrumento contendo informações sociodemográficas, um questionário validado (com foco na percepção acerca da preceptoria), acrescido de uma questão sobre o modelo pedagógico adotado. Resultado: A amostra do estudo foi composta majoritariamente por preceptores do sexo feminino (60%) e com maior titulação na residência médica (96,6%). Um percentual expressivo (80%) informou não possuir formação pedagógica para desenvolver a preceptoria. O modelo pedagógico tradicional foi o mais adotado na prática docente dos preceptores. Conclusão: Mostra-se a importância do diagnóstico situacional da preceptoria na residência médica em Anestesiologia, apontando a necessidade de formação docente para o desenvolvimento da atividade do preceptor, bem como sua valorização adequada, objetivando a melhor formação médica.

Abstract This paper investigates the properties of the polyaniline (PANI) on açaí vegetable fiber (AVF), hereafter referred to as PANI-COATED:AVF. Scanning electron and atomic force microscopy showed that the incorporation of PANI produced a linear surface, while optical microscopy images showed that the semiconductor layer was flawed. The complex impedance measurements performed at room temperature indicated that the electrical properties of PANI were fully transferred to the PANI-COATED:AVF and that the Cole-Cole approach dominated over a frequency range from 1 Hz to 100 kHz. Thermogravimetric analysis revealed a thermal stability range of 0° to 300°C. Finally, the combination of PANI with AVF was a successful due to the ease of processing and obtaining semiconductor filaments with wide ranges of thermal and electrical stability. This article is a complement to another recently published [doi.org/10.1002/pc.27068].

ABSTRACT Objective: to create and validate an app that establishes the diabetic foot risk degree by associating the patients’ health conditions. Methodology: a methodological study conducted between March 2019 and December 2021 in Crato - CE - Brazil, and divided into three phases: 1) Review of the national and international guidelines; 2) Creation of the educational technology; and 3) Face and content validation of the technology. This study followed the guidelines set forth in the Revised Standards for Quality Improvement Reporting Excellence guide. Results: in the review phase, similar content was identified between the guidelines for designing and organizing the content. The technology that was created enabled data collection, as well as diabetic foot risk assessment and classification. A total of 18 judges evaluated the instrument in the validation stage, obtaining a CVI value of 0.96. Conclusion: the study may contribute to improving the indicators referring to hospitalizations, amputations, reduced mobility, dependence, frailty and mortality resulting from diabetic foot.

RESUMEN Objetivo: crear y validar una aplicación que establezca el grado de riesgo del pie diabético asociándolo a sus condiciones de salud. Metodología: estudio metodológico realizado entre marzo de 2019 y diciembre de 2021, en Crato, CE, Brasil, dividido en tres fases: 1) Revisión de directrices nacionales e internacionales; 2) Creación de la tecnología educativa y 3) Validación del contenido y la apariencia de la tecnología. Este estudio siguió los lineamientos de la guía Revised Standards for Quality Improvement Reporting Excellence. Resultados: en la fase de revisión, se identificaron contenidos similares entre las directrices para el diseño y la organización del constructo. La tecnología creada permitió recolectar datos, evaluar y clasificar el riesgo del pie diabético. En la etapa de validación, 18 jueces evaluaron el instrumento, que contó con un IVC de 0,96. Conclusión: el estudio puede contribuir a mejorar los indicadores de hospitalización, amputación, movilidad reducida, dependencia, fragilidad y mortalidad derivados del pie diabético.

RESUMO Objetivo: construir e validar um aplicativo que estabeleça o grau de risco do pé diabético associando suas condições de saúde. Metodologia: estudo metodológico realizado entre março de 2019 a dezembro de 2021, em Crato - CE - Brasil, dividido em três fases: 1) Revisão das diretrizes nacionais e internacionais; 2) Construção da tecnologia educativa e 3) Validação do conteúdo e aparência da tecnologia. Este estudo seguiu as diretrizes do guia Revised Standards for Quality Improvement Reporting Excellence. Resultados: na fase de revisão, identificou-se conteúdo semelhante entre as diretrizes para o delineamento e a organização do constructo. A tecnologia construída possibilitou a coleta de dados, avaliação e classificação de risco do pé diabético. Na etapa de validação, 18 juízes avaliaram o instrumento, que teve o IVC 0,96. Conclusão: o estudo poderá contribuir para melhorar os indicadores referente as hospitalizações, amputações, mobilidade diminuída, dependência, fragilidade e mortalidade advindos do pé diabético.

Abstract Background: Systemic arterial hypertension (SAH) and diabetes mellitus (DM) are grievances that are sensitive to the measures of promotion and prevention; however, they interfere with the quality of life (QL). Objective: The aim of this study was to evaluate the QL in elderly people with SAH and DM and compare their impact on the QL of these groups. Method: It was used as a methodology a sectional, domiciliary-based study in which the data were collected using a questionnaire with sociodemographic information, clinical and QL, through the WhoQol-Bref and analyzed in the SPSS software. Results: A total of 498 elderly people were evaluated, of whom 9.64% had DM, 53.21% had SAH, and 37.15% had both diseases. The majority were women (66.9%), from 60 to 69 years old (49.4%), mixed race (61.6%), from 9 to 11 years of study (53%), family budget under two minimum wages (48.6%), married (52.8%), and using five or more medications (18.9%). There was a difference among the groups (SAH, QL, or both) in the physical domain (p=0.003) and in the social relationships (p=0.017). In the physical domain, the post hoc tests showed better QL in SAH groups compared to the others. Conclusions: The patients with SAH showed better general QL. The psychological domain was the least affected and the environment domain was the most affected.

Resumo Introdução: Hipertensão (HAS) e diabetes mellitus (DM) são agravos cujo controle é sensível a medidas de promoção e prevenção, no entanto interferem na qualidade de vida (QV). Objetivos: Avaliar a QV em idosos com HAS e DM e comparar o impacto na QV entre esses grupos. Método: Utilizou-se como metodologia um estudo seccional de base domiciliar, cujos dados foram coletados por meio de questionário com informações sociodemográficas, clínicas e de QV, por meio do WhoQol-Bref, e analisados por meio do software SPSS. Resultados: Foram avaliados 498 idosos, 9,64% com DM, 53,21% com HAS e 37,15% com ambos os agravos. A maioria era mulher (66,9%) entre 60 e 69 anos (49,4%), parda (61,6%), com nove a doze anos de estudo (53%), renda familiar abaixo de dois salários mínimos (48,6%), casada (52,8%) e 18,9% era polifármaca. Houve diferença entre os grupos (HAS, DM ou ambos) no domínio físico (p=0,003) e relações sociais (p=0,017). No domínio físico os testes post hoc apontaram melhor QV no grupo HAS em relação aos demais (p<0,05). Conclusões: Os pacientes com HAS apresentaram melhor QV geral. O domínio psicológico foi o menos afetado, e o domínio meio ambiente, o que mais sofreu impacto.

Abstract A complete genome of the first anellovirus infecting the wild felid Leopardus pardalis (ocelot) and a partial genome were assembled and annotated through high-throughput sequencing protocols followed by Sanger sequencing validation. The full-length virus obtained comprises 2,003 bp, while the partial genome comprises 1,224 bp. Phylogenetic analysis grouped these two sequences in two distinct clusters related to previously described Felidae anelloviruses. The ORF1 of the partial genome was identified as a new species provisionally called Torque teno ocelot virus, with 53.6% identity with its sister lineage. The complete genome was inferred as a new representative of the Torque teno felid virus 3 species, with 73.28% identity to the closest reference. This study expands known virus diversity and the host span of anelloviruses.

Resumo O objetivo deste artigo foi caracterizar as disciplinas relacionadas ao lazer dos cursos de Educação Física de instituições privadas e públicas. Foi utilizada metodologia mista e a técnica Análise Categorial. Como conclusões, as disciplinas relacionadas ao lazer ocupam maior espaço nas instituições públicas comparativamente às privadas e não têm localização semestral específica dentro desses currículos. Sobre os temas, as disciplinas nas instituições privadas se aproximam principalmente da recreação e nas públicas da educação. Já os enfoques são semelhantes nas instituições privadas e públicas e as disciplinas valorizam principalmente o enfoque na história, teoria ou conceito de lazer. Sobre as bibliografias, a obra mais constatada é “Introdução ao Lazer” de Victor Andrade Melo e Edmundo Drummond Alves Júnior e o autor mais citado é Nelson Carvalho de Marcellino. Categorial conclusões currículos temas educação história bibliografias Introdução Lazer Marcellino

Resumen El objetivo de este artículo fue caracterizar los temas relacionados con el ocio en los cursos de Educación Física en instituciones públicas y privadas. Se utilizó la metodología mixta y la técnica de Análisis de Categorías. Como conclusiones, las materias relacionadas con el ocio ocupan más espacio en las instituciones públicas en comparación con las privadas y no tienen una ubicación semestral específica dentro de estos planes de estudio. En cuanto a las temáticas, las asignaturas en las instituciones privadas se relacionan principalmente con la recreación y en las instituciones públicas con la educación. Por otro lado, los enfoques son similares en instituciones públicas y privadas, y las disciplinas valoran principalmente el enfoque en la historia, teoría o concepto de ocio. En cuanto a las bibliografías, la obra más consultada es “Introdução ao Lazer” de Victor Andrade Melo y Edmundo Drummond Alves Júnior, y el autor más citado es Nelson Carvalho de Marcellino. Categorías conclusiones estudio temáticas educación lado historia bibliografías Introdução Lazer Júnior Marcellino

Abstract The objective of this article was to characterize the subjects related to leisure in Physical Education courses in private and public institutions. Mixed methodology and the Category Analysis technique were used. In conclusion, leisure-related subjects occupy more space in public institutions compared to private ones and do not have a specific semester location within these curricula. Regarding the themes, subjects in private institutions are mainly related to recreation and in public ones to education. On the other hand, the approaches are similar in private and public institutions and the disciplines mainly value the focus on the history, theory or concept of leisure. About the bibliographies, the most verified work is “Introdução ao Lazer” by Victor Andrade Melo and Edmundo Drummond Alves Júnior and the most cited author is Nelson Carvalho de Marcellino. used conclusion leisurerelated curricula themes education hand history bibliographies Introdução Lazer Marcellino

Abstract Objective: To evaluate the association between dose of skin-to-skin contact (SSC) per day and initiation time with the occurrence of deaths in newborns with weight up to 1800g. Method: Multicentric cohort in five Brazilian neonatal units, including newborns with a birth weight of ≤1800g. The time of SSC was registered in individual file, by the team or family during the hospitalization. Maternal and newborn data were obtained through questionnaires applied to mothers and in medical records. Classification Tree was used for data analysis. Results: The performance of the first SSC after 206h was significantly associated with death (p = 0.02). Although there was no association between SSC/day and death (p = 0.09), the number of deaths among those who performed more than 146.9 minutes/day was lower (3;1.5%) than among those who performed this practice for a shorter time (13;6.4%), a fact considered of great clinical importance. Early and late infections present statistically significant associations with the outcome. The chance of death was equal to zero when there was no early infection in the group with the longest duration of SSC. This probability was also equal to zero in the absence of late sepsis for the group with less than 146.9 minutes/day of SSC. Conclusions: The first SSC before 206 hours of life is recommended in order to observe a reduction in the risk of neonatal death. Staying in SSC for more than 146.9 min/day seems to be clinically beneficial for these neonates mostly when it was associated with the absence of infection.

Resumo: Introdução: Transtornos mentais comuns (TMC) têm sido frequentemente identificados entre universitários na área de saúde, especialmente em Medicina. Acredita-se que características inerentes ao curso exerçam potencial influência na saúde mental do estudante. Quando se adiciona o contexto de pandemia com as restrições sociais inerentes, os determinantes psicológicos relacionados à desconhecida patologia e o temor do rápido alastramento do novo coronavírus, existe a possibilidade de potencialização dos fatores de riscos para o sofrimento psíquico nessa população. Objetivo: Este estudo teve como objetivo estimar a prevalência de TMC entre estudantes de Medicina durante a pandemia da Covid-19, analisando seus principais determinantes nos âmbitos acadêmico, social e econômico. Método: Trata-se de estudo transversal, realizado com 388 estudantes de Medicina em Salvador, na Bahia. Por meio da plataforma Google Forms, coletaram-se dados sociodemográficos e acadêmicos, sobre hábitos de vida, comorbidades e sintomas de transtornos não psicóticos mensurados pelo Self-Reporting Questionnaire (SRQ-20). Resultado: A prevalência de TMC foi de 39,7% entre os estudantes de Medicina, sendo de 47,4% no ciclo básico, 40,3% no ciclo clínico e 12,3% no internato. Entre os fatores associados ao surgimento de TMC, estão sedentarismo, tabagismo, uso de substâncias que favoreçam o desempenho acadêmico, insatisfação com o próprio rendimento acadêmico, má qualidade de sono, falta de apetite, cefaleia frequente, má digestão, ideação suicida e tristeza. Observou-se maior índice de transtornos mentais não psicóticos entre as mulheres, não havendo diferença quanto ao ciclo acadêmico e à natureza administrativa da instituição de ensino. Conclusão: Durante a pandemia de Covid-19, demonstrou-se uma expressiva prevalência de TMC entre estudantes de Medicina do sexo feminino, brancos, solteiros, que residem com familiares e não possuem renda própria. Apesar de estudos sugerirem aumento da prevalência nos universitários no momento atual, os dados deste estudo permaneceram concordantes com a literatura anterior à pandemia, configurando o próprio curso de Medicina como principal fator de risco para taxas superiores de TMC nessa população. Entretanto, novos estudos acerca do impacto em longo prazo da pandemia na saúde mental dos universitários ainda são necessários.

Abstract: Introduction: Common mental disorders (CMD) have been frequently identified among university students in the health area, especially in Medicine. It is believed that characteristics inherent to the course have a potential influence on the student’s mental health. When adding the pandemic context, with its inherent social restrictions, the psychological determinants related to the unknown pathology and the fear of the rapid spread of the new coronavirus, there is the possibility of increasing the risk factors for psychological distress in this population. Objective: To estimate the prevalence of CMD among medical students during the COVID-19 pandemic, analyzing its main determinants in the academic, social and economic spheres. Method: Cross-sectional study, carried out with 388 medical students in Salvador/BA., Data on sociodemographic and academic aspects, life habits, comorbidities and symptoms of non-psychotic disorders were collected using the Google Forms platform, measured by the Self-Reporting Questionnaire (SRQ-20). Results: The prevalence of CMD was 39.7% among medical students, with 47.4% in the basic cycle, 40.3% in the clinical cycle and 12.3% in the internship period. Among the factors associated with the emergence of CMD are sedentary lifestyle, smoking, use of substances that enhance academic performance, dissatisfaction with one’s academic performance, poor sleep quality, lack of appetite, frequent headaches, poor digestion, suicidal ideation and sadness. There was a higher rate of non-psychotic mental disorders among women, with no difference regarding the academic cycle and the administrative type of the educational institution. Conclusion: During the COVID-19 pandemic, a significant prevalence of CMD was demonstrated among female, white, single medical students who live with family members and do not have their own income. Although studies suggest an increase in the prevalence among university students at the present time, the data from the present study remain in agreement with the literature data prior to the pandemic, showing that the medical course itself is the main risk factor for higher rates of CMD in this population. However, further studies on the long-term impact of the pandemic on the mental health of university students are still necessary.

RESUMO Esta pesquisa teve como objetivo avaliar a incorporação da nanossílica (NS) em argamassas de reboco produzidas com agregado fino reciclado (RFA). Inicialmente, foi realizado um estudo em pastas cimentícias substituindo o cimento Portland por NS nos teores de 0%, 0,4%, 0,6%, 0,8% e 1,0%. As amostras foram submetidas a análises de espalhamento, reologia, calorimetria, difração de raios X (DRX), espectroscopia de infravermelho por transformada de Fourier (FTIR) e resistência à compressão aos 28 dias. Os resultados demonstraram que as pastas com 0,4% NS e 0,6% NS apresentaram aumento de resistência de 55% e 58%, respectivamente, devido à maior formação de silicato de cálcio hidratado (C-S-H), quando comparada à pasta de referência. Diante disso, foram produzidas as amostras de RFA, substituindo o cimento Portland por 0% NS, 0,4% NS e 0,6% NS. Aos 28 dias, o desempenho mecânico, a microestrutura e a durabilidade foram avaliados por meio da resistência à flexão e compressão, microscopia eletrônica de varredura (MEV), módulo de elasticidade dinâmico e absorção de água por capilaridade. A partir dos resultados, concluiu-se que as amostras de RFA com 0,4% NS resultaram no teor ótimo de nanossílica, produzindo um aumento na resistência à compressão e redução na sorptividade de água, em relação às demais misturas. As imagens de MEV sugerem que NS reagiu com a portlandita formada a partir da hidratação do cimento, resultando em um enchimento eficiente dos poros do RFA, melhorando o desenvolvimento microestrutural das amostras.

ABSTRACT This paper evaluated the incorporation of nanosilica (NS) in rendering mortars produced with recycled fine aggregate (RFA). Initially, a study was carried out on cementitious pastes, replacing Portland cement with NS at levels of 0%, 0.4%, 0.6%, 0.8%, and 1.0%. The samples were submitted to scattering, rheology, calorimetry, x-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and compressive strength analysis at 28 days. The results demonstrated that the pastes with 0.4% NS and 0.6% NS presented an increase in strength of 55% and 58%, respectively, due to a greater formation of calcium silicate hydrate (C-S-H), when compared with the reference paste. From that, the RFA samples were produced, replacing Portland cement with 0% NS, 0.4% NS, and 0.6% NS. At 28 days, mechanical performance, microstructure, and durability were evaluated by means of flexural strength and compression, scanning electron microscopy (SEM), dynamic elasticity module, and water absorption by capillarity. From the results, it was concluded that the RFA samples with 0.4% NS resulted in the optimal nanosilica content, increasing compressive strength values and reducing the sorptivity, in relation to the other mixtures. The SEM images suggest that NS reacted with portlandite formed of the cement hydration, improving the microstructural development of the samples.

Abstract Aim: To evaluate the chronic effects of resistance training on resting blood pressure, handgrip strength, gait speed, and Timed Up and Go test (TUG) in normotensive and hypertensive elderly individuals. Methods: Experimental study based on TREND. Hypertensive patients were diagnosed by an independent doctor. Before and after 12 weeks of progressive resistance training, we evaluated blood pressure, heart rate, body composition, Timed Up and Go test, gait speed, and handgrip strength. Results: Sample consisted of 41 participants divided into two groups (normotensive n = 28; hypertensive n = 13). We observed significant values in the reduction of blood pressure levels only in the group of hypertensive participants. In functionality outcomes, we observed significant values in all tests and both groups. Outcomes contemplate effect sizes ranging from small to moderate. Conclusion: Progressive resistance training lowers resting blood pressure levels, increases handgrip strength, and improves physical functional performance. Although the normotensive group did not show a reduction in blood pressure levels, an improvement was observed in the functional physical tests.