SUMMARY OBJECTIVE: Colonic diverticulosis might be caused by low-fiber dietary habits, gastrointestinal motility disorders, and colonic wall resistance changes, which might also affect the upper gastrointestinal system mucosa. Therefore, the present study aims to answer whether the gastric histopathological findings of the cases with diverge from those without. METHODS: This retrospective cross-sectional study included 184 cases who underwent both upper and lower gastrointestinal endoscopy procedures between January 2020 and December 2022. Notably, 84 cases were colonic diverticulosis, while the rest of the study group was control. Their demographic, laboratory, and histopathological findings were compared meticulously. RESULTS: The median ages for the colonic diverticulosis and control were 67.07±8.14 and 66.29±15.83 years, respectively, and no statistical difference concerning the age and gender distribution between them was recognized. The median levels of white blood cells, neutrophils, glucose, creatinine, and aspartate aminotransferase in colonic diverticulosis were significantly increased compared to control. As for pathological comparison, colonic diverticulosis had a higher prevalence of Helicobacter pylori (45.2 vs. 38%), while atrophy and intestinal metaplasia prevalence were nearly the same in the groups, without significance regarding Helicobacter pylori. CONCLUSION: Consequently, colonic diverticulosis should not be overlooked, particularly when the abovementioned laboratory parameters are augmented in a dyspeptic patient. A correlation might be raised between Helicobacter pylori and colonic diverticulosis. Eradication therapy might help attenuate the risk of colonic diverticulosis when Helicobacter pylori has emerged in a patient. OBJECTIVE lowfiber low fiber habits disorders changes mucosa Therefore METHODS crosssectional cross sectional 18 202 2022 Notably 8 demographic meticulously RESULTS 6707814 67 07 14 67.07±8.1 66291583 66 29 15 83 66.29±15.8 years respectively recognized cells neutrophils glucose creatinine comparison 45.2 452 45 2 (45. vs 38%, 38 38% , 38%) groups CONCLUSION Consequently overlooked patient 1 20 670781 6 0 67.07±8. 6629158 66.29±15. 45. 4 (45 3 67078 67.07±8 662915 66.29±15 (4 6707 67.07± 66291 66.29±1 ( 670 67.07 6629 66.29± 67.0 662 66.29 67. 66.2 66.

ABSTRACT Since SARS-CoV-2 disease (COVID-19) has been labeled as a pandemic, it took the spotlight in the differential diagnosis for patients presenting with acute respiratory and systemic symptoms. Leptospirosis is one of the most common zoonoses in the world, yet it is mainly a disease of differential diagnosis for places that do not have it as an endemic. Due to the high burden of COVID-19 on the healthcare field, patients suffering from other infections may have been inadvertently neglected. COVID-19 infection can mimic other infectious diseases and can confuse physicians in their search for a confirmatory diagnosis. Nonetheless, it is very crucial to broaden the differential diagnosis and keep diseases like leptospirosis within the differential diagnosis despite its rarity, especially in patients presenting with unexplained systemic infectious symptoms. This is a unique case of a patient who presented with dyspnea, jaundice and change in urine color who was suspected to be COVID-19 positive. After a detailed investigation, the patient was diagnosed with leptospirosis instead of COVID-19 and was treated with plasmapheresis and antibiotics accordingly. SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- COVID19 COVID 19 (COVID-19 pandemic symptoms world endemic COVID-1 field neglected Nonetheless rarity dyspnea positive investigation accordingly SARS-CoV COVID1 1 (COVID-1 COVID- (COVID- (COVID

ABSTRACT Leptospirosis is one of the most common zoonotic bacterial infections worldwide. It is an infection that usually affects people with low socioeconomic status, with morbidity and mortality risk. The clinical course of the disease may range from mild, featuring nonspecific clinical signs and symptoms, to severe, resulting in death. The respective studies conducted in Turkey indicate that leptospirosis seropositivity in animals and humans is higher in coastal and rural areas. Turkey’s Eastern Black Sea Region has a humid climate with heavy rainfalls and a large population of mice and other rodents. However, a Leptospira interrogans serovar Bratislava case is yet to be reported in this region. This article reports the case of a 38-year-old patient who presented fever and acute renal failure and was diagnosed with Leptospira interrogans serovar Bratislava after hospitalization. worldwide status risk mild symptoms severe death areas Turkeys s rodents However region 38yearold yearold 38 year old hospitalization 3