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SUMMARY OBJECTIVES: The coronavirus disease pandemic has become a major global health crisis since 2019. Recent data show the association of diabetes, hypertension, and obesity with poor related outcomes in coronavirus disease infection. This descriptive study aimed to identify the clinical and laboratory parameters in patients with acute respiratory syndrome and confirmed severe acute respiratory syndrome coronavirus 2 infection. METHODS: In this cross-sectional study, we analyzed data of 409 patients admitted to a referral hospital in Rio Grande do Sul, Brazil, with coronavirus disease infection confirmed by reverse transcription polymerase chain reaction. Clinical, laboratory, and imaging data were collected retrospectively from electronic medical records using a template with the variables of interest. RESULTS: The average age was 64 years (52–73), and the body mass index was 27 kg/m² (22.1–31.2). Hypertension, diabetes, and obesity were observed in 58, 33, and 32% of the patients, respectively. Patients admitted to an intensive care unit were older [66 years (53–74) vs. 59 years (42.2–71.7)], with significantly higher impairment on chest computed tomography [75% (50–75) vs. 50% (25–60)] and received higher doses of corticosteroid therapy [39.4 mg (14.3–70.3) vs. 6 mg (6–14.7)]. Hematological parameters were lower in critically ill patients, with greater differences observed on the fifth day of hospitalization [hemoglobin 11.5 g/dL (9.5–13.1) vs. 12.8 g/dL (11.5–14.2), platelets 235,000 μL (143,000–357,000) vs. 270,000 μL (192,000–377,000), and lymphocytes 900 μL (555–1,500) vs. 1,629 μL (1,141–2,329)]. C-reactive protein levels and kidney function were also worse in intensive care unit patients. The mortality rate was significantly higher in the intensive care unit compared to the basic care unit (62.8 vs. 12.2%). CONCLUSION: Our findings suggest that metabolic and cardiovascular comorbidities, as well as abnormal hematological parameters, are common findings among patients with severe respiratory syndrome related to coronavirus disease. OBJECTIVES 2019 diabetes hypertension METHODS crosssectional cross sectional 40 Sul Brazil reaction Clinical interest RESULTS 52–73, 5273 52–73 , 52 73 (52–73) kgm² kgm kg m² m kg/m 22.1–31.2. 221312 22.1–31.2 . 22 1 31 (22.1–31.2) Hypertension 58 33 32 respectively 66 [6 53–74 5374 53 74 (53–74 vs 5 42.2–71.7, 422717 42.2–71.7 42 71 7 (42.2–71.7)] 75% 75 [75 50–75 5075 50 (50–75 25–60 2560 25 60 (25–60) 39.4 394 39 4 [39. 14.3–70.3 143703 14 3 70 (14.3–70.3 6–14.7. 6147 6–14.7 (6–14.7)] hemoglobin 115 11 11. gdL g dL 9.5–13.1 95131 9 13 (9.5–13.1 128 12 8 12. 11.5–14.2, 115142 11.5–14.2 (11.5–14.2) 235000 235 000 235,00 143,000–357,000 143000357000 143 357 (143,000–357,000 270000 270 270,00 192,000–377,000, 192000377000 192,000–377,000 192 377 (192,000–377,000) 90 555–1,500 5551500 555 500 (555–1,500 1629 629 1,62 1,141–2,329. 11412329 1,141–2,329 141 329 (1,141–2,329)] Creactive C reactive 62.8 628 62 (62. 12.2%. 122 12.2% 12.2%) CONCLUSION comorbidities 201 527 52–7 (52–73 22131 22.1–31. (22.1–31.2 [ 53–7 537 (53–7 42271 42.2–71. (42.2–71.7) [7 50–7 507 (50–7 25–6 256 (25–60 39. [39 14.3–70. 14370 (14.3–70. 614 6–14. (6–14.7) 9.5–13. 9513 (9.5–13. 11514 11.5–14. (11.5–14.2 23500 23 00 235,0 143,000–357,00 14300035700 35 (143,000–357,00 27000 270,0 19200037700 192,000–377,00 19 37 (192,000–377,000 555–1,50 555150 55 (555–1,50 162 1,6 1141232 1,141–2,32 (1,141–2,329) 62. (62 12.2 20 52– (52–7 2213 22.1–31 (22.1–31. 53– (53– 4227 42.2–71 (42.2–71.7 50– (50– 25– (25–6 [3 14.3–70 1437 (14.3–70 61 6–14 (6–14.7 9.5–13 951 (9.5–13 1151 11.5–14 (11.5–14. 2350 0 235, 143,000–357,0 1430003570 (143,000–357,0 2700 270, 1920003770 192,000–377,0 (192,000–377,00 555–1,5 55515 (555–1,5 16 1, 114123 1,141–2,3 (1,141–2,329 (6 (52– 221 22.1–3 (22.1–31 (53 422 42.2–7 (42.2–71. (50 (25– 14.3–7 (14.3–7 6–1 (6–14. 9.5–1 95 (9.5–1 11.5–1 (11.5–14 143,000–357, 143000357 (143,000–357, 192000377 192,000–377, (192,000–377,0 555–1, 5551 (555–1, 11412 1,141–2, (1,141–2,32 ( (52 22.1– (22.1–3 (5 42.2– (42.2–71 (25 14.3– (14.3– 6– (6–14 9.5– (9.5– 11.5– (11.5–1 143,000–357 14300035 (143,000–357 19200037 192,000–377 (192,000–377, 555–1 (555–1 1141 1,141–2 (1,141–2,3 22.1 (22.1– 42.2 (42.2–7 (2 14.3 (14.3 (6–1 9.5 (9.5 (11.5– 143,000–35 1430003 (143,000–35 1920003 192,000–37 (192,000–377 555– (555– 114 1,141– (1,141–2, 22. (22.1 42. (42.2– 14. (14. (6– 9. (9. (11.5 143,000–3 143000 (143,000–3 192000 192,000–3 (192,000–37 (555 1,141 (1,141–2 (22. (42.2 (14 (9 (11. 143,000– 14300 (143,000– 19200 192,000– (192,000–3 (55 1,14 (1,141– (22 (42. (1 (11 143,000 1430 (143,000 1920 192,000 (192,000– 1,1 (1,141 (42 143,00 (143,00 192,00 (192,000 (1,14 (4 143,0 (143,0 192,0 (192,00 (1,1 143, (143, 192, (192,0 (1, (143 (192, (192 (19