Pesquisa | SciELO

ABSTRACT This study was conducted to investigate the polymorphism of the silence information regulator 5 (SIRT5) gene in 103 Congjiang Xiang pigs from Southwest China. We searched for SNP (single nucleotide polymorphism) loci of SIRT5 gene through sequence alignment and PCR. We obtained nine SNP loci: g.14135 A>C (intron 6), g.14247 C>A (intron 6), g.14305 C>T (exon 7), g.14335 C>T (exon 7), g.16603 T>C (intron 7), g.16613 T>C (intron 7), g.16800 G>A (intron 7), g.16812 C>G (intron 7), and g.16916 A>G (exon 8). Further analysis of SNP genotypes associated with the carcass traits of skin thickness, backfat thickness, and eye muscle area was carried out in pigs. We found that the genotypes g.14305 C>T (CC) and g.16812 C>G (CG) had certain advantages for improving the carcass traits of Congjiang Xiang pigs. The haplotype combination of the SIRT5 gene that improved skin thickness was H2H3:CCGGCTCA. These results may provide empirical support for molecular-based breeding of carcass traits in Congjiang Xiang pigs. SIRT (SIRT5 10 China single PCR g14135 g 14135 g.1413 AC A C intron 6, 6 , 6) g14247 14247 g.1424 CA g14305 14305 g.1430 CT T exon 7, 7 7) g14335 14335 g.1433 g16603 16603 g.1660 TC g16613 16613 g.1661 g16800 16800 g.1680 GA G g16812 16812 g.1681 CG g16916 16916 g.1691 AG 8. 8 . 8) CC (CC (CG H2H3CCGGCTCA. H2H3CCGGCTCA HHCCGGCTCA H2H3 CCGGCTCA. CCGGCTCA H H2H3:CCGGCTCA molecularbased molecular based (SIRT 1 g1413 1413 g.141 g1424 1424 g.142 g1430 1430 g.143 g1433 1433 g1660 1660 g.166 g1661 1661 g1680 1680 g.168 g1681 1681 g1691 1691 g.169 HH H2H g141 141 g.14 g142 142 g143 143 g166 166 g.16 g168 168 g169 169 g14 14 g.1 g16 16 g1 g.

https://doi.org/10.37496/rbz5320220122

A detailed multi-omics analysis of GNB2 gene in human cancers
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Zhang, L.

; Sahar, A. M.

; Li, C.

; Chaudhary, A.

; Yousaf, I.

; Saeedah, M. A.

; Mubarak, A.

; Haris, M.

; Nawaz, M.

; Reem, M. A.

; Ramadan, F. A.

; Mostafa, A. A. M.

; Feng, W.

; Hameed, Y.

Brazilian Journal of Biology

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2024, Volume 84 elocation e260169

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo A proteína 2 de ligação de nucleotídeos de guanina (GNB2) codifica a subunidade β2 (Gβ2) do complexo da proteína G. Tendo em vista o aumento da demanda de biomarcadores em câncer, o presente estudo foi planejado para explorar extensivamente a variação da expressão de GNB2 e seus papéis em diferentes cânceres usando bancos de dados on-line disponíveis e metodologia diversificada. Em vista de nossos resultados, o GNB2 foi notavelmente regulado para cima em relação aos controles correspondentes em 23 tipos de câncer. Além disso, a expressão elevada de GNB2 foi associada à redução da sobrevida global (OS) do carcinoma hepatocelular do fígado (LIHC) e do adenocarcinoma do reto (READ) apenas em todos os tipos de câncer analisados. Isso implica que GNB2 desempenha um papel vital na tumorigênese de LIHC e READ. Várias análises adicionais também exploraram seis vias críticas e poucas correlações relacionadas à expressão de GNB2 e diferentes outros parâmetros, como metilação do promotor, pureza do tumor, infiltração de células T CD8+, alteração genética e drogas quimioterápicas. Em conclusão, o gene GNB2 foi identificado neste estudo como um potencial biomarcador compartilhado (diagnóstico e prognóstico) de LIHC e READ.

Abstract The Guanine-nucleotide binding protein 2 (GNB2) encodes for β2 subunit (Gβ2) of the G-protein complex. Keeping in view the increased demand of reliable biomarkers in cancer, the current study was planned to extensively explored GNB2 expression variation and its roles in different cancers using online available databases and diverse methodology. In view of our results, the GNB2 was notably up-regulated relative to corresponding controls in twenty three cancer types. As well, the elevated expression of GNB2 was found to be associated with the reduced overall survival (OS) of the Liver Hepatocellular Carcinoma (LIHC) and Rectum Adenocarcinoma (READ) only out of all analyzed cancer types. This implies GNB2 plays vital role in the tumorigenesis of LIHC and READ. Several additional analysis also explored six critical pathways and few important correlations related to GNB2 expression and different other parameters such as promoter methylation, tumor purity, CD8+ T immune cells infiltration, and genetic alteration, and chemotherapeutic drugs. In conclusion, GNB2 gene has been identified in this study as a shared potential biomarker (diagnostic and prognostic) of LIHC and READ.

https://doi.org/10.1590/1519-6984.260169

Preparation and application of carboxymethylated and phosphatised Melaleuca polysaccharide
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

YAN, You-Yu

; XU, Chang-Yuan

; YUAN, Shuai

; SHI, Lu-Ying

; ZHANG, Xi-Feng

Food Science and Technology

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2023, Volume 43 elocation e130022

Resumo: En | Texto: En | PDF: En

Abstract Polysaccharides are a class of biological macromolecules made up of sugar chains with multiple glycosidic bonds. To explore the extracted, purified, carboxymethylated and phosphorylated modified to obtained carboxymethylated polysaccharides (HSPS) and phosphorylated polysaccharides (HSPP), and the HSPS and HSPP were characterized and analyzed, and their antioxidant activity measured. Response surface design was used for the synthesis process of HSPS and HSPP, the structure characterization and antioxidant activities of HSPS and HSPP were evaluated. The results showed that the Mw and Mn of HSP were 14.66 kDa and 8.39 kDa, respectively. The monosaccharides were mainly galactose, glucose, xylose, and arabinose in a molar ratio of 37.68%: 24.43%: 13.63%: 9.18%. The optimal synthesis conditions for HSPS were as follows: reaction time of 2.01 h, reaction temperature of 44.61°C and the amount of monochloroacetic acid necessary was 1.18 g. The optimal synthesis conditions for HSPP were: reaction time of 4.28 h, reaction temperature of 80.78°C, and reaction pH of 8.98. HSPS and HSPP have scavenging effects on ABTS, super oxideanion and hydroxyl radicals. The HSPS and HSPP were characterized and analyzed, and their antioxidant activity measured. bonds extracted purified (HSPS , (HSPP) analyzed measured evaluated 1466 14 66 14.6 839 8 39 8.3 respectively galactose glucose xylose 37.68% 3768 37 68 24.43% 2443 24 43 13.63% 1363 13 63 918 9 18 9.18% follows 201 2 01 2.0 h 4461C C 44 61 118 1 1.1 g 428 4 28 4.2 8078C 80 78 80.78°C 898 98 8.98 ABTS radicals (HSPP 146 6 14. 83 3 8. 37.68 376 24.43 244 13.63 136 91 9.18 20 0 2. 11 1. 42 4. 7 89 8.9 37.6 24.4 13.6 9.1 37. 24. 13. 9.

https://doi.org/10.1590/fst.130022

Bioinformatics-based design of a fusion vaccine with CTLA-4 variable region to combat Brucella Bioinformaticsbased Bioinformatics based CTLA4 CTLA 4 CTLA-
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Guo, W.H.

; Zhu, Y.J.

; Haimiti, G.

; Xie, X.R.

; Niu, C.

; Li, M.

; Shi, J.

; Yin, Z.W.

; Yu, M.K.

; Ding, J.B.

; Zhang, F.B.

Brazilian Journal of Medical and Biological Research

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2023, Volume 56 elocation e12938

Resumo: En | Texto: En | PDF: En

Brucellosis has become a global zoonotic disease, seriously endangering the health of people all over the world. Vaccination is an effective strategy for protection against Brucella infection in livestock in developed countries. However, current vaccines are pathogenic to humans and pregnant animals, which limits their use. Therefore, it is very important to improve the safety and immune protection of Brucella vaccine. In this study, different bioinformatics approaches were carried out to predict the physicochemical properties, T/B epitope, and tertiary structure of Omp2b and Omp31. Then, these two proteins were sequentially linked, and the Cytotoxic T lymphocyte associated antigen-4 (CTLA-4) variable region was fused to the N-terminal of the epitope sequence. In addition, molecular docking was performed to show that the structure of the fusion protein vaccine had strong affinity with B7 (B7-1, B7-2). This study showed that the designed vaccine containing CTLA-4 had high potency against Brucella, which could provide a reference for the future development of efficient brucellosis vaccines. disease world countries However animals use Therefore properties TB B Ompb Omp b Omp31 Then linked antigen4 antigen 4 antigen- CTLA4 CTLA (CTLA-4 Nterminal N terminal sequence addition B71, B71 1, 1 (B7-1 B72. B72 2 . B7-2) CTLA- Omp3 (CTLA- (B7- B7-2 (CTLA (B7 B7- (B

https://doi.org/10.1590/1414-431x2023e12938

Evaluation of a sugarcane juice beverage fermented by Ganoderma lucidum: nutritional and antioxidant activity
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

WANG, Qingfu

; HUANG, Qinghua

; ZHANG, Liulian

; WANG, Lining

; HU, Biao

; XU, Riyi

; LIANG, Lei

; PING, Zhaohua

Food Science and Technology

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 42 elocation e84822

Resumo: En | Texto: En | PDF: En

Abstract A novel sugarcane juice beverage was successfully produced by liquid fermentation of G. lucidum and homogenate process with selecting the day 10 fermentation broth as the raw materials. The beverage was evaluated for its sensory, nutritional and antioxidant activities. The results showed that the beverage by the G.lucidum fermentation was rich in polysaccharides, triterpenes, proteins, and flavonoids, which were all significantly higher than sugarcane juice, especially polysaccharides and triterpenoids. And the beverage could retain the sensory quality of sugarcane juice and could therefore be favored by the consumers. The in vitro antioxidant activity showed that the beverage had high scavenging and reducing abilities. DPPH and ABTS•+ radical scavenging rate of 1 mL fermented beverage were similar to 0.04 mg/mL VC, while the hydroxyl radical scavenging rate and reducing power of 1 mL of fermented beverage were similar to 1.68 mg/mL and 0.19 mg/mL VC, respectively. Taken together, the sugarcane juice fermented beverage was a natural flavor substances with high antioxidant activity and non-toxicity.

https://doi.org/10.1590/fst.84822

Physicochemical, Rheological, & Sensory Characteristics of Yogurt Fortified with Ball-Milled Roasted Chickpea Powder (Cicer arietinum L.)
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

RAZA, Husnain

; AMEER, Kashif

; ZAABOUL, Farah

; SHOAIB, Muhammad

; ZHAO, Chang-Cheng

; ALI, Barkat

; SHAHZAD, Muhammad Talha

; ABID, Muhammad

; REN, Xiaofeng

; ZHANG, Lianfu

Food Science and Technology

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 42 elocation e61020

Resumo: En | Texto: En | PDF: En

Abstract This study was aimed at evaluation of effects of ball-milled roasted chickpea (RC) powder on physicochemical, rheological and sensorial properties of yogurt supplemented with RC levels of 1 (RCY1), 2 (RCY2), 3 (RCY3), 4 (RCY4), and 5 g/100 mL (RCY5). Results showed a gradual decline in the pH of pre-inoculated samples with corresponding increases in powder concentration from 1 to 5 g/ 100 mL. Degrees of lightness and yellowness increased in supplemented samples as compared to control (RCY0). Higher firmness was exhibited by RCY3 and RCY5 samples in the range of 59.39-78.56 g. RCY3 showed the highest consistency value (1480.214 g/s). Overall, the syneresis was significantly lower (p<0.05) in supplemented samples as compared to control. The addition levels of more than 3% RC resulted in smoother and more gradual dispersive patterns of particles, and RCY4 showed the most prominent polydispersity and resembled RCY5. Comparatively, supplemented samples exhibited a significantly lower degree of shear-thinning as compared to control samples. RCY5 showed the maximum texture score among all supplemented samples, and supplemented samples showed comparable sensory attributes to those of control samples. It was evident from this study that RC powder can be employed as a functional food ingredient in yogurt production.

https://doi.org/10.1590/fst.61020

Oil chemical traits of kernels of different almond cultivars from China
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

WANG, Qin

; LIU, Fenglan

; MENG, Jiangfei

; MAO, Jinmei

; ZHANG, Liuping

; WANG, Jianyou

Food Science and Technology

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 42 elocation e27621

Resumo: En | Texto: En | PDF: En

ABSTRACT Traditional cultivars account for a large part of worldwide almond cultivars. However, the oil chemical traits of traditional almond cultivars in China remain unclear. Here, the oil chemical traits of four native and two traditional almond cultivars grown in China were determined. The content of unsaturated and monounsaturated fatty acids ranged from 93.02% to 93.29% and 75.24% to 77.98%, respectively. The tocopherol content varied between 25.15 and 18.37 mg/100 g. β-sitosterol content varied between 93.06% and 94.40%. VB1, VB2, VB3, and VB6 contents ranged from 0.11 to 0.23, 0.26 to 0.73, 370.00 to 1272.00, and 0.05 to 0.07 mg/100 g, respectively. The levels of squalene and phospholipids ranged from 131.20 to 274.80 mg/kg and 1.18 to 1.47 mg/g, respectively. These results indicated that the composition and content of fatty acids, tocopherols, sterols, VB1, VB2, VB3, VB6, squalene, and phospholipids in almond kernels were significantly different among the investigated cultivars.

https://doi.org/10.1590/fst.27621

Molecular structures and functional exploration of NDA family genes respond tolerant to alkaline stress in Gossypium hirsutum L.
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Fan, Yapeng

; Zhang, Yuexin

; Rui, Cun

; Zhang, Hong

; Xu, Nan

; Wang, Jing

; Han, Mingge

; Lu, Xuke

; Chen, Xiugui

; Wang, Delong

; Wang, Shuai

; Guo, Lixue

; Zhao, Lanjie

; Huang, Hui

; Wang, Junjuan

; Sun, Liangqing

; Chen, Chao

; Ye, Wuwei

Biological Research

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 55 elocation 4

Resumo: En | Texto: En | PDF: En

Abstract Background: The internal NAD(P)H dehydrogenase (NDA) gene family was a member of the NAD(P)H dehydrogenase (ND) gene family, mainly involved in the non-phosphorylated respiratory pathways in mitochondria and played crucial roles in response to abiotic stress. Methods: The whole genome identification, structure analysis and expression pattern of NDA gene family were conducted to analyze the NDA gene family. Results: There were 51, 52, 26, and 24 NDA genes identified in G. hirsutum, G. barbadense, G. arboreum and G. raimondii, respectively. According to the structural characteristics of genes and traits of phylogenetic tree, we divided the NDA gene family into 8 clades. Gene structure analysis showed that the NDA gene family was relatively conservative. The four Gossypium species had good collinearity, and segmental duplication played an important role in the evolution of the NDA gene family. Analysis of cis-elements showed that most GhNDA genes contained cis-elements related to light response and plant hormones (ABA, MeJA and GA). The analysis of the expression patterns of GhNDA genes under different alkaline stress showed that GhNDA genes were actively involved in the response to alkaline stress, possibly through different molecular mechanisms. By analyzing the existing RNA-Seq data after alkaline stress, it was found that an NDA family gene GhNDA32 was expressed, and then theGhNDA32 was silenced by virus-induced gene silencing (VIGS). By observing the phenotype, we found that the wilting degree of silenced plants was much higher than that of the control plant after alkaline treatment, suggesting that GhNDA32 gene was involved in the response to alkaline stress. Conclusions: In this study, GhNDAs participated in response to alkaline stress, especially NaHCO3 stress. It was of great significance for the future research on the molecular mechanism of NDA gene family in responding to abiotic stresses.

https://doi.org/10.1186/s40659-022-00372-8 42 downloads

Quinoa starch microspheres for drug delivery: preparation and their characteristics
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

LUO, Yang

; NI, Futai

; GUO, Mingzhu

; LIU, Juan

; CHEN, Huan

; ZHANG, Sitong

; LI, Yanli

; CHEN, Guang

; WANG, Gang

Food Science and Technology

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 42 elocation e126421

Resumo: En | Texto: En | PDF: En

Abstract Quinoa starch microparticles (QSMs) fabricated with unhydrolyzed quinoa starch (QS) by inverse microemulsion technology could be used as medicine delivery and cosmetic accessories. The size distribution of QSMs was uniform at 28.5 μM, and the adsorption capacity of methylene blue was 0.82 mg/ g. The optimum preparation process was as follows: a QS mass fraction of 9%, an epoxy chloropropane content of 1%, an amount of oil phase of 100 mL, a span 80 of 3 mg/mL, and a stirring speed of 400 r/min for 3 h at room temperature and pressure. The QSMs were spherical, ellipsoidal in shape with the specific surface area of 1.676 m2/g. The crystallinity of the QSMs increased from 1.24% to 16.8% after crosslinking. The maximum thermal degradation temperature of the QSMs rose slightly than QS. It will be a promising material for application as a drug carrier and in cosmetics.

https://doi.org/10.1590/fst.126421

10.

Protective effects of sodium ferulate on flap transplantation via anti-inflammatory modulation and oxidative stress inhibition
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Sun, Y.D.

; Gao, Y.S.

; Xu, L.W.

; Zhang, Y.F.

; Cheng, C.

; Wei, K.C.

; Lin, Jian

; Chen, G.

; Liu, C.Y.

; Li, Q.F.

Brazilian Journal of Medical and Biological Research

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2021, Volume 54 Nº 7 elocation e10520

Resumo: En | Texto: En | PDF: En

Ischemia-reperfusion injury (IRI) has brought attention to flap failure in reconstructive surgery. To improve the prognosis of skin transplantation, we performed experimental IRI by surgical obstruction of blood flow and used sodium ferulate (SF) to prevent IRI in rats. After SF treatment, the morphological and histological changes of the skin flaps were observed by H&E and Masson's trichrome staining. We also detected the expression levels of COX-1, HO-1, and Ki67 by immunohistochemical and western blot analysis. Moreover, enzyme-linked immunosorbent assay was used to identify the content of tumor necrosis factor (TNF)-α, myeloperoxidase (MPO), malondialdehyde (MDA), and nitric oxide (NO) in peripheral blood and skin tissue. Compared with the model group, SF treatment significantly improved the recovered flap area (%) and promoted collagen synthesis. Cyclooxygenase-2 (COX-2) expression was significantly inhibited by heme oxygenase-1 (HO-1) induction after SF treatment. Furthermore, SF significantly inhibited the levels of TNF-α in peripheral blood, MPO and MDA in the skin tissue, and the increased synthesis of NO. Our results showed the protective effects of SF on IRI after flap transplantation and we believe that the protective effects of SF was closely related to the alleviation of the inflammatory response and the inhibition of the oxidative stress injury.

https://doi.org/10.1590/1414-431x2020e10520 220 downloads

11.

Baryon Acoustic Oscillations from Integrated Neutral Gas Observations: an instrument to observe the 21cm hydrogen line in the redshift range 0.13 < z < 0.45 – status update
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

WUENSCHE, CARLOS A.

; ABDALLA, ELCIO

; ABDALLA, FILIPE

; BAROSI, LUCIANO

; WANG, BIN

; AN, RUI

; BARRETOS, JOÃO A. M.

; BATTYE, RICHARD

; BRITO, FRANCISCO A.

; BROWNE, IAN

; CORREIA, DANIEL

; COSTA, ANDRÉ A.

; DELABROUILLE, JACQUES

; DICKINSON, CLIVE

; FENG, CHANG

; FERREIRA, ELISA G. M.

; FORNAZIER, KARIN

; DE GASPERIS, GIANCARLO

; GUTIERREZ, PRISCILA

; HARPER, STUART

; LANDIM, RICARDO G.

; LICCARDO, VINCENZO

; MA, YIN-ZHE

; MACHADO, TELMO

; MAFFEI, BRUNO

; MARINS, ALESSANDRO

; MENDES, MILENA M. M.

; MERICIA, EDUARDO

; MONSTEIN, CHRISTIAN

; MOTTA, PABLO

; NOVAES, CAMILA

; OTOBONE, CARLOS H.

; PEEL, MICHAEL

; QUEIROZ, AMILCAR R.

; RADCLIFFE, CHRISTOPHER

; REMAZEILLES, MATHIEU

; RIBEIRO, RAFAEL M. G.

; SANG, YU

; SANTOS, JULIANA F. R.

; SANTOS, LARISSA

; SANTOS, MARCELO. V.

; SHAN, CHENXI

; SILVA, GUSTAVO B.

; VIEIRA, FREDERICO

; VIEIRA, JORDANY

; VILLELA, THYRSO

; XIAO, LINFENG

; YANG, WEIQIANG

; ZHANG, JIAJUN

; ZHANG, XUE

; ZHU, ZENGHAO

Anais da Academia Brasileira de Ciências

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2021, Volume 93 elocation e20201096

Resumo: En | Texto: En | PDF: En

Abstract BINGO (BAO from Integrated Neutral Gas Observations) is a unique radio telescope designed to map the intensity of neutral hydrogen distribution at cosmological distances, making the first detection of Baryon Acoustic Oscillations (BAO) in the frequency band 980 MHz - 1260 MHz, corresponding to a redshift range 0.127 < z < 0.449. BAO is one of the most powerful probes of cosmological parameters and BINGO was designed to detect the BAO signal to a level that makes it possible to put new constraints on the equation of state of dark energy. The telescope will be built in Paraíba, Brazil and consists of two \thicksim 40m mirrors, a feedhorn array of 50 horns, and no moving parts, working as a drift-scan instrument. It will cover a 15 ^{\circ} ∘ declination strip centered at \sim \delta ∼ δ =-15 ^{\circ} ∘, mapping \sim ∼ 5400 square degrees in the sky. The BINGO consortium is led by University of São Paulo with co-leadership at National Institute for Space Research and Campina Grande Federal University (Brazil). Telescope subsystems have already been fabricated and tested, and the dish and structure fabrication are expected to start in late 2020, as well as the road and terrain preparation.

https://doi.org/10.1590/0001-3765202120201096 413 downloads

12.

Assessment of components of Gingko biloba leaves collected from different regions of China that contribute to its antioxidant effects for improved quality monitoring
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

LI, Li

; ZHANG, Ming-Xu

; WANG, Xiao-Yue

; YANG, Yun-Li

; GONG, Xue

; WANG, Cong-Cong

; XU, Jin-Fan

; LI, Min-Hui

Food Science and Technology

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2021, Volume 41 Supl. 2 Páginas 676 - 683

Resumo: En | Texto: En | PDF: En

Abstract Ginkgo biloba leaves are commonly used in traditional Chinese medicine. Owing to its wide distribution across China with varying geographical environments and climatic characteristics, G. biloba leaf products have different active ingredients and degrees of activities, which poses a challenge for quality control and standardization. We aimed to identify the key factors contributing to the quality of G. biloba based on assessment of anti-aging and antioxidative components. G. biloba leaf samples collected from 14 different regions in China were analyzed for antioxidant activities by the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) free radical scavenging assay, and the levels of terpene lactones and flavonoids were quantified by ultra-performance liquid chromatography-tandem mass spectroscopy and high performance liquid chromatography. Correlation analysis attributed the antioxidant activity of G. biloba leaf samples of different origins to isoginkgetin and ginkgetin, which also affected the matrix metalloproteinase-1 levels of fibroblasts, determined using enzyme-linked immunosorbent assay and reverse transcription-polymerase chain reaction. Therefore, appropriate quality control of a collected G. biloba sample could be achieved by determining the levels of isoginkgetin and ginkgetin as anti-aging and antioxidant components. The results further provide a foundation for the application of G. biloba leaves as an antioxidant raw material.

https://doi.org/10.1590/fst.33620 2 downloads

13.

Gynura segetum induces hepatic sinusoidal obstruction syndrome in mice by impairing autophagy
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Zhang, Hui

; Jia, Shu

; Jin, Lianyu

; MB, Jianzuo Yao

; Shen, Zhihong

; Wu, Jingyi

; Yao, Xiaokun

; Chen, Danwei

; Zhang, Congcong

; Yu, Shufang

; Zhu, Ningwei

; Jin, Lexiao

; Yao, Xiaomin

Acta Cirúrgica Brasileira

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2021, Volume 36 Nº 11 elocation e361104

Resumo: En | Texto: En | PDF: En

ABSTRACT Purpose: To investigate the underlying mechanism of hepatic sinusoidal obstruction syndrome (HSOS) induced by Gynura segetum by measuring autophagy in mouse models. Methods: The model group was administered G. segetum (30 g/kg/d) by gavage, while the normal control group was administered an equal volume of saline daily for five weeks. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), hepatic histopathological examinations, and Masson staining were performed to evaluate liver injury. Liver intercellular adhesion molecule-1 (ICAM-1) and P-selectin were evaluated by immunohistochemistry. Hepatocellular apoptosis was assessed using the terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay. Protein expression levels of autophagy markers were measured using Western blot analysis. Results: Gynura segetum was found to significantly induce liver injury compared with control mice, as evidenced by the increase of serum transaminases, a decrease in triglyceride levels, and histopathological changes in mice. Gynura segetum remarkably induced hepatocellular apoptosis and upregulated the expressions of ICAM-1 and P-selectin and also downregulated the protein expression levels of LC3, Atg12 and cytoplasmic polyadenylation element binding protein. Conclusions: Our results suggested that G. segetum induced liver injury with HSOS, and it was partly due to its ability to impair the autophagy pathway.

https://doi.org/10.1590/acb361104

14.

Yeast culture (Saccharomyces cerevisiae) and its active metabolites affect the cecal microbiome of broilers
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Sun, Z.

; Zhen, Y.

; Li, T.

; Aschalew, N.D.

; Wang, T.

; Chen, X.

; Zhao, W.

; Zhang, X.

; Qin, G.

South African Journal of Animal Science

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2021, Volume 51 Nº 6 Páginas 678 - 688

Resumo: En | Texto: En | PDF: En

Yeast cultures (YCs) are defined as promising feed additives that maintain the health of birds and improve growth performance by modulating gut microbiota. YCs contain effective metabolites such as glycine, fructose, inositol, galactose, and sucrose. This study investigated the effects of YCs and their effective metabolites on carcass traits and cecal microflora in broilers. A total of 280 one-day-old mixed-sex Arbor Acres broilers were randomly allocated to seven groups. The basal diet (control DZ) was supplemented with various proportions of glycine, fructose, inositol, galactose, and sucrose (Groups A, B, and C), 24-hour grown Saccharomyces cerevisiae cultures (Group D) (YC), and a commercial yeast culture product (SZ) at concentrations of 0.1% and 1% (Groups E and F). Bodyweight of broilers was correlated positively with proportions of Proteobacteria in Group C and Lactobacillus and Roseburia in Group B (P <0.05). Broilers fed diets supplemented with YC or its active metabolites had the highest proportions of bacteria involved in nucleotide metabolism, and amino acid and carbohydrate metabolism. These results suggested that the dietary addition of YC could alter the proliferation of beneficial bacteria in broilers.

https://doi.org/10.4314/sajas.v51i6.1 24 downloads

15.

Bioactive metabolites in of Ginkgo biloba leaves: variations by seasonal, meteorological and soil
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Lin, Y.

; Lou, K.

; Wu, G.

; Wu, X.

; Zhou, X.

; Feng, Y.

; Zhang, H.

; Yu, Ping

Brazilian Journal of Biology

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Dez 2020, Volume 80 Nº 4 Páginas 790 - 797

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Ginkgo biloba é um fitoterápico tradicional da medicina chinesa que contém vários componentes que contribuem para suas notáveis bioatividades. Variações sazonais, meteorológicos e de plantio do solo sobre os teores fitoquímicos em folhas de G. biloba, devido aos efeitos do crescimento meteorológico e parâmetros do solo, foram investigadas neste estudo. As folhas de G. biloba foram coletadas em diferentes meses e na província de Zhejiang, os teores de flavonas (quercetina, kaempferol e isorhamnetina) e lactonas terpênicas (bilobalida, ginkgolídeos A, B e C) foram quantificados por Cromatografia Líquida de Alta Eficiência (CLAE) e pelo método do detector de dispersão da luz por evaporação. Os métodos estabelecidos foram validados com boa linearidade, precisão, repetibilidade, estabilidade e recuperação. Uma análise abrangente sugeriu que o tempo de colheita adequado para G. biloba foi em outubro na província de Zhejiang. O resultado da análise de correlação com fatores meteorológicos mostra que a temperatura e a precipitação não têm efeito significativo sobre os principais componentes de G. biloba. Além disso, o tipo e composição (Mn e Zn) do solo apresentaram efeito significativo sobre o teor de flavonoides e lactonas terpênicas. Este estudo enriqueceu o conhecimento sobre o valor de desenvolvimento e utilização das folhas de G. biloba e foi útil para determinar o melhor tempo de colheita e condição de crescimento.

Abstract Ginkgo biloba is a traditional Chinese herbal medicine containing multiple components that contribute to its notable bioactivities. Variations of seasonal, meteorological and planting soil on the phytochemicals contents in G. biloba leaves due to the effects of growth meteorological and soil parameters were investigated in this study. The leaves of G. biloba were collected from different months and place in Zhejiang province, the contents of flavones (quercetin, kaempferol and isorhamnetin) and terpene lactones (bilobalide, ginkgolides A, B and C) were quantified by high performance liquid chromatography (HPLC) and the evaporative light scattering detector (ELSD) method. The established methods were validated with good linearity, precision, repeatability, stability, and recovery. Comprehensive analysis suggested the proper harvest time for G. biloba was in October of Zhejiang province. The result of correlation analysis with meteorological factors shows that the temperature and precipitation have non-significant effect on the main components of G. biloba. In addition, the type and content (Mn and Zn) of the soil showed significantly effect on the content of flavonoids and terpene lactones. This study enriched the knowledge on the development and utilization value of the G. biloba leaves and was useful for determining the optimal harvest time and growing condition.

https://doi.org/10.1590/1519-6984.220519 738 downloads

Exibindo

itens por página

Página de 4 Próxima

Selecione um ou mais resultados

Todos Ordem alfabética

Resultados

Gráfico comparativo Download CSV

Visualizar estatísticas de

Enviar resultado

E-mail do(s) destinatários*

Utilize ; (ponto e vírgula) para mais de um e-mail.

Enviar por e-mail

Esta página

Registros selecionados

Todos os registros (max. 300)

Alterar remetente, assunto e comentários

Seu email

Assunto

Comentários

Alterar remetente, assunto e comentários

Exportar resultados

Formato de exportação:

RIS (para EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citação

CSV (para Excel, etc)

Exportar:

Esta página

Itens selecionados

Todos os registros (max. 2000)

Mostrar mais

Sem resultados

Não foram encontrados documentos para sua pesquisa

Glossário e ajuda para busca

Você pode enriquecer sua busca de uma forma muito simples. Use os índices de pesquisa combinados com os conectores (AND ou OR) e especifique cada vez mais sua busca.

Por exemplo, se você deseja buscar artigos sobre
casos de dengue no Brasil em 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

Veja abaixo a lista completa de índices de pesquisa que podem ser usados:

Cód. do Índice	Elemento
ti	título do artigo
au	autor
kw	palavras-chave do artigo
subject	assunto (palavras do título, resumo e palavras-chave)
ab	resumo
ta	título abreviado da revista (ex. Cad. Saúde Pública)
journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

Todo o conteúdo de www.scielo.org, exceto onde está identificado, está licenciado sob uma Licença Creative Commons.
saiba mais »