Abstract Liquid composite armor has demonstrated excellent performance in protecting against shaped charge jets. Currently, most existing theoretical calculation models for the velocity range of the disturbed jet approximate the cone angle of the shockwave front as the Mach angle. However, indiscriminately equating the cone angle of the shockwave front with the Mach angle can lead to significant errors in the calculated velocity range of the disturbed jet. To address this issue, this study focuses on investigating the variation of the cone angle of the shockwave front within the liquid composite protective structure. Firstly, a dimensional analysis was conducted to determine the functional relationship between the cone angle of the shockwave front and relevant parameters. Then, the process of jet penetrating liquid composite protective structure was simulated by Autodyn. The results demonstrated that the normalized cone angle solely depends on the normalized diameter within the critical angle. By fitting the simulation data, the formula for calculating the cone angle of the shockwave front was derived. jets Currently However issue Firstly parameters Then Autodyn data derived

Evolving educational paradigms and cultural expectations present distinct challenges for novice English teachers. This study explores the crucial role of emotional preparedness in novice English teachers, particularly in China, where gaps in understanding and support are evident. Employing a qualitative grounded theory approach, the study identifies key emotional management skills and institutional support factors via in-depth interviews, incorporating a psycho-social framework to explore how emotional regulation and self-awareness are crucial for teacher resilience and effectiveness. The findings underline the importance of personal emotional management skills, such as self-awareness and emotional regulation, alongside institutional support mechanisms, including professional development and peer networks. The research underscores the need for targeted training programmes that enhance personal and organisational support to boost teachers' emotional resilience. These insights are pivotal for developing interventions that improve novice teachers' emotional capabilities, promoting a more supportive educational milieu in China.

ABSTRACT The aim of this study is to simplify the difficult excavation that is caused by the root-sand complex in the process of harvesting Cyperus esculentus in the desert of Xinjiang by performing mechanical tests and analysis of the interaction between the vibrating excavation shovel and the rotary blade on the root-sand complex. The rotary blade number, rotary blade speed and digging depth were used as the test parameters, and the Cyperus esculentus breakage rate, root-grass crushing rate, and soil carrying rate were used as the test indicators. The characteristics of the influence of various factors and their interaction on the crushing and separation of the root-sand complex were explored. A parameter combination optimization model is verified by experimental data. The test results showed that the optimal combination was as follows: the number of rotary blades was 20, the rotational speed of the rotary blade was 373 r/min, and the digging depth was 12 cm. At this time, the Cyperus esculentus breakage rate, root-grass crushing rate, and soil carrying rate were 2.62%, 63.68% and 55.40%, respectively. This study can support the development of a Cyperus esculentus harvester suitable for deserts in Xinjiang. rootsand root sand parameters rootgrass grass indicators explored data follows 20 37 rmin r min r/min 1 cm time 262 2 62 2.62% 6368 63 68 63.68 5540 55 40 55.40% respectively 3 26 6 2.62 636 63.6 554 5 4 55.40 2.6 63. 55.4 2. 55.

Abstract Introduction: At present, there are few reports regarding the issue of aortic reoperation due to its complexity and high risk and individual differences among patients. Methods: From November 2016 to December 2017, the data from 35 cases of aortic reoperation at our institution, out of 212 consecutive aortic repairs, were reviewed. We retrospectively summarized and analyzed their surgical indications, operative data, time interval from previous aortic repair, and outcomes. The time intervals until reoperation were analyzed for differences. Results: Patients’ mean age was 40.9±14.5 years, and 25 of them were men (71.4%). The indications for reoperation were aortic valvular problem (14.3%), aneurysmal dilatation (25.7%), pseudoaneurysm formation due to anastomotic leakage (43.2%), and aortic dissection (17.1%). For patients who had underwent primarily emergency operations due to aortic dissection, the time interval until reoperation (4.8±3.2 years) was significantly shorter than that of the whole group (5.5±3.6 years, P<0.01). Among the 35 reoperations, Sun’s procedure was selected for 16 patients (45.7%) with total aortic arch reconstruction. The average follow-up was 12 months (range 9-15 months). Hospital mortality was 5.7% (two patients). Among the hospital survivors there were no cases of death, rupture of residual dissection, paraplegia, or central nervous system complications during the follow-up period. Conclusion: Patients with acute aortic dissection required repeat surgery significantly earlier compared to other diseases. As to reoperation strategy, we recommend Sun’s procedure as the choice for extended arch reconstruction since minimal effect on overall mortality and complication rates were found.

ABSTRACT Insulin antibodies (IAs) induced by exogenous insulin rarely cause hypoglycemia. However, insulin autoantibodies (IAAs) in insulin autoimmune syndrome (IAS) can cause hypoglycemia. The typical manifestations of IAS are fasting or postprandial hypoglycemia, elevated insulin level, decreased C-peptide levels, and positive IAA. We report a 45-year-old male with type 1 diabetes mellitus (T1DM) treated with insulin analogues suffering from recurrent hypoglycemic coma and diabetic ketoacidosis (DKA). His symptoms were caused by exogenous insulin and were similar to IAS. A possible reason was that exogenous insulin induced IA. IA titers were 61.95% (normal: < 5%), and the concentrations of insulin and C-peptide were > 300 mU/L and < 0.02 nmol/L when hypoglycemia occurred. Based on his clinical symptoms and other examinations, he was diagnosed with hyperinsulinemic hypoglycemia caused by IA. His symptoms improved after changing insulin regimens from insulin lispro plus insulin detemir to recombinant human insulin (Gensulin R) and starting prednisone.

Los anticuerpos contra la insulina (AI) inducidos por la insulina exógena raramente causan hipoglucemia. No obstante, los autoanticuerpos contra la insulina (AIA) en el síndrome autoinmune de insulina (SAI) pueden causar hipoglucemia. Las manifestaciones típicas del SAI son la hipoglucemia en ayunas o posprandial, niveles elevados de insulina, la disminución del nivel de péptido C y AIA positivos. Presentamos un paciente hombre de 45 años con diabetes mellitus de tipo 1 (DMT1) tratado con análogos de insulina, que sufría comas hipoglucémicos recurrentes y cetoacidosis diabética (CAD). Sus síntomas fueron causados por la insulina exógena y fueron similares al SAI. La posible razón fue que la insulina exógena indujo AI. El título de AI era del 61,95% (Normal: < 5%), y las concentraciones de insulina y péptido C eran > 300 mU/L y < 0,02 nmol/L cuando se producía la hipoglucemia. Basados en sus síntomas clínicos y otros exámenes, se le diagnosticó hipoglucemia hiperinsulinémica causada por la AI. Sus síntomas mejoraron después de cambiar el régimen de insulina de lispro más insulina detemir a insulina humana recombinante (Gensulin R) y de empezar a tomar prednisona.

Abstract Compared with central penetration, the eccentric penetration of jet into a liquid-filled composite armor (LCA) shows a more obvious lateral displacement due to the asymmetric impact by the shock wave and liquid radial reflux. Based on this characteristic, the reaming process in the liquid layer during the shaped charge jet (SCJ) penetrates into the strongly-constrained liquid-filled composite armor (SLCA) eccentrically, the interference process of jet is subjected to the asymmetric impact by the shock wave and liquid radial reflux, and the lateral movement process of the SCJ under lateral force loading is analyzed to study the influence of SLCA on the stability of incoming SCJ during eccentric penetration. Theoretical and X-ray experimental results show that when the eccentricity distance is [0 mm, 12 mm], the severely disturbed velocity range and total disturbed velocity range of the SCJ increase with the increase of the eccentricity distance, while the maximum lateral displacement of the SCJ decreases slightly with the increase of the eccentricity distance at [1 mm, 12 mm].

This study aimed to observe the effects of lung-protective ventilation (LPV) on oxygenation index (OI) and postoperative pulmonary complications (PPCs) after laparoscopic radical gastrectomy in middle-aged and elderly patients. A total of 120 patients who were scheduled to undergo laparoscopic radical gastrectomy with an expected time of >3 h were randomly divided into conventional ventilation (CV group) with tidal volume (TV) of 10 mL/kg without positive end-expiratory pressure (PEEP), and lung-protective ventilation (PV group) with 7 mL/kg TV and personal level of PEEP with regular recruitment maneuver every 30 min. Measurements of OI, modified clinical pulmonary infection score (mCPIS), and PPCs were assessed during the perioperative period. Fifty-seven patients in the CV group and 58 in the PV group participated in the data analysis. Patients in the PV group showed better pulmonary dynamic compliance, OI, and peripheral capillary oxygen saturation during and after surgery. The mCPIS was significantly lower in the PV group than in the CV group after surgery. The incidence rate of PPCs was lower in the PV group than in the CV group and the difference was significant in patients whose ventilation time was longer than 6 h in both groups. LPV during laparoscopic radical gastrectomy significantly improved pulmonary oxygenation function and reduced postoperative mCPIS and the incidence of PPCs during the early period after surgery of middle-aged and elderly patients, especially patients whose mechanical ventilation time was longer than 6 h.

Abstract: In this article, hydrogeological parameters were determined by a single well pumping test. Over the course of the study, BETCO was used to eliminate the effects of atmospheric pressure changes on water level based on the regression deconvolution method. The aquifer test was used to analyze data and to calculate hydrogeological parameters. Finally, from the three unconfined aquifer models, though the Boulton model cannot successfully gain well-fitting results, the Theis model with Jacob correction and the Neuman model results obtained hydrogeological parameters by curve-fitting. Additionally, permeability coefficient of the two models is in good agreement with previous research, which can provide a reference for further study in the hinterland of the desert, especially for the construction of hydrological modeling research.

Resumen: En el presente artículo se determinaron los parámetros hidrogeológicos mediante una prueba de bombeo de un solo pozo. Durante el estudio se utilizó BETCO para eliminar los efectos de los cambios de presión atmosférica en el nivel del agua con base en el método de regresión-deconvolución. Se utilizó la prueba de acuíferos para analizar los datos y para calcular los parámetros hidrogeológicos. Finalmente, de los tres modelos de acuíferos confinados, aunque el modelo Boulton no puede arrojar resultados bien ajustados, el modelo Theis con corrección de Jacob y el modelo Neuman obtuvieron resultados de parámetros hidrogeológicos mediante ajuste de curvas. Además, el coeficiente de permeabilidad de los dos modelos concuerda bien con investigaciones anteriores, las cuales pueden servir de referencia para estudios posteriores en el interior del desierto, especialmente para la investigación de modelos hidrológicos.

Abstract: In order to perceive the effect of drip irrigation with saline water in the desert hinterland on plant growth of shelterbelts and underground environment (vadose zone and groundwater), by developing water-saving irrigation technology to ensure the scientifically substantiated utilization of water resources, four different irrigation cycle experiments (difference in irrigation period I: 12d; IV: 25d; II & III: 25d in the summer and the respective spring and autumn periods, which were the same: 15d and 20d, respectively) were carried out during the irrigation season in four different regions of well irrigation area. In this paper, regular on-site investigation was adopted to observe soil, water, and salt. Single-factor analysis of variance and least significant difference (LSD) are used to analyze the data acquired by the survey method and for measuring plant growth, complemented with the comparison of groundwater level and chemical index before and after irrigation. The results showed that the reduction of annual irrigation volume from 420 mm to 201.6 mm had almost no effect on plant growth and could save more than 50% of the water as compared to treatment I. Considering the impact on the height-growth of Tamarix, treatment II could be optimized, so that more than 30% of the water could be saved as compared to treatment I. Three days after irrigation, the salt was leached through the soil body into the groundwater. The groundwater level in the shelterbelt area, total dissolved solids (TDS), and total hardness exhibited an upward trend. Six days after irrigation, the high salt concentration region was found at a depth of 0–30 cm.

Resumen: Con la finalidad de entender el efecto del riego por goteo con agua salina en el crecimiento de plantas de cortinas rompevientos y en el ambiente subterráneo del interior del desierto (zona no saturada y aguas subterráneas), mediante el desarrollo de tecnología de riego para asegurar el aprovechamiento científicamente justificado de los recursos hídricos, se efectuaron cuatro experimentos de riego en ciclo de ahorro de agua (diferencia en periodo de riego I: 12d; IV: 25d; II y III: 25d en verano; sus respectivos periodos de primavera y otoño fueron los mismos: de 15 d y 20 d, respectivamente) durante la temporada de riego en cuatro diferentes regiones del área de riego con agua de pozo. En este trabajo se adoptó la investigación regular in situ para observar suelo, agua y salinidad. Se utiliza el análisis de varianza de un solo factor y la diferencia mínima significativa (LSD) para analizar los datos obtenidos por el método de encuesta y para medir el crecimiento de las plantas; complementando lo anterior con la comparación de nivel de agua subterránea y el índice químico antes y después del riego. Los resultados mostraron que la reducción de volumen de riego anual de 420 a 201.6 mm casi no tuvo efecto en el crecimiento de las plantas, y podría ahorrar más del 50% de agua, en comparación con el tratamiento I. Si se considera el impacto en el crecimiento de altura de Tamarix, el tratamiento II podría ser optimizado, por lo que se podría ahorrar más de un 30% del agua, en comparación con el tratamiento I. Tres días después del riego, la sal se lixivia a través del cuerpo del suelo a las aguas subterráneas; el nivel de agua subterránea en el área de la cortina rompevientos, los sólidos disueltos totales (SDT) y la dureza total mostraron una tendencia ascendente. Seis días después del riego, la región de alta concentración de sales se encontró a una profundidad de 0 a 30 centímetros.

A Cu-10Fe alloy with magnetron sputtered Al films was irradiated by high current pulsed electron beam (HCPEB) with various pulse numbers, next changes of its microstructure and corrosion property were investigated. Compared with the initial sample, microhardness and corrosion resistance of the aluminized Cu-10Fe alloys after the HCPEB treatment are remarkably improved with increasing pulse numbers. This improvement could be attributed to formation of Al2Cu intermetallic compounds, occurrence of liquid phase separation and grain refinement in the surface layer of the Cu-10Fe alloy during the process of rapid remelting and solidification induced by the HCPEB treatment.

Abstract: Bullous pemphigoid is a blistering autoimmune disease characterized by two hemidesmosomal proteins (anti-BP180 and 230). Pemphigus, by contrast, is characterized by two autoantibodies (anti-desmoglein 1 and 3). Coexistence of autoantibodies of bullous pemphigoid and pemphigus in a patient is rare. A 25-year-old male patient was admitted to our hospital, reporting a 3-month history of multiple papules, vesicles, and erosions over an extensive erythema on the entire body. Laboratory tests showed high levels of serum IgE, anti-BP180 antibodies, and anti-desmoglein 1 and 3. Histopathologic and immunopathologic features were characterized by bullous pemphigoid. No improvement was seen with systemic corticosteroid therapy, however, pulse corticosteriod therapy combined with methylprednisolone, immunosuppressants, immunomodulators, and plasmapheresis led to the recovery of his condition with numerous milia.

Microstructures of CuCr25 and CuCr50 alloys treated by high current pulsed electron beam (HCPEB) were investigated in this work. The microstructure and solidification behavior of the Cr-rich phases were characterized by scanning electron microscopy (SEM). Results show that a remelting layer of 3~5 μm is formed on the surface of Cu-Cr alloys. The microstructure of the remelting layer reveals that both the fine dispersion of Cr-rich spheroids and the craters appear after HCPEB treatment. This means that metastable liquid phase separation occurs during rapid solidification under HCPEB treatment. In addition, the appearance of relatively large craters in the subsurface of Cr-rich particles with the distance about 5-10 μm provides direct evidences supporting results reported by other researchers in terms of numerical simulation temperature field of HCPEB treatments.

Background:Intracranial abscesses are associated with high mortality. Staphylococcus aureus is one of the main pathogens that cause intracranial infection. Until now, there is no report to identify the key effectors of S. aureus during the intracranial infection.Methods:The murine intracranial abscesses model induced by S. aureuswas constructed. The vital sign and survival rate of mice were observed to evaluate the infection. Histological examination was used to diagnose the pathological alterations of mouse tissues. The sensitivity of S. aureus to whole blood was evaluated by whole-blood killing assay.Results:In murine intracranial abscesses model, it was shown that the mortality caused by the accessory gene regulator (agr) locus deficient strain was significant decreased compared with its parent strain. Moreover, we found that RNAIII, the effector of agr system, was essential for the intracranial infection caused by S. aureus. In the further investigation, it was shown that restoration the expression of α-toxin in agr deficient strain could partially recover the mortality in the murine intracranial abscesses model.Conclusion:Our data suggested that the agr system of S. aureus is an important virulence determinant in the induction and mortality of intracranial abscesses in mice.

Severe fever with thrombocytopenia syndrome (SFTS) associated with severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging infectious disease. 12 patients with severe fever with thrombocytopenia syndrome in our study were presented mainly with fever and severe malaise. The clinical manifestations typically became worse on the 6th or 7th day. The average fever time is 9.11 ± 1.54 days. Most of them had multiorgan dysfunction, and part of them had hemophagocytic lymphohistiocytosis histiocytosis (HLH). The characteristic laboratory findings in the early stage were the drop of white blood cells (WBC), platelets (PLT) and serum Ca++, while increase of aspartate amino transferase (AST), creatine kinase (CK), and lactate dehydrogenase (LDH). CD3+CD4+ were significantly decreased, while CD3-CD56+ were significantly increased, whereas CD3+CD8+ were constantly elevated throughout the disease course. Ten to 14 days after illness onset, symptoms were improved, accompanied by resolution of laboratory abnormalities. These results indicate that severe fever with thrombocytopenia syndrome has an acute onset and self-limited course. It is a systemic infection. The host immune response caused tissues and organs injury. The improvement of symptoms and laboratory tests is consistent with the elimination of the virus and recover of immune response. Further investigation should be done in order to better understand this disease and guide the clinical treatment.

The VPl gene of enterovirus 71 (EV71) was synthesized, construct a recombinant plasmid pET15b/VP1 and expressed in E. coli BL21. The recombinant VP1 protein could specifically react with EV71-infected patient sera without the cross-reaction with serum antibodies of coxsackievirus A16 (CA16), A4, A5, B3 and B5 as well as echovirus 6. In acute and convalescent phases, IgM and IgG antibodies of 182 serum samples were detected by ELISA with recombinant VP1 protein as a coated antigen. The results showed that the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of IgM antibodies in serum samples for the diagnosis of EV71 infection were 90.1, 98.4, 98.8 and 88.7%, respectively; similarly, those of IgG antibodies in serum samples were 82.4, 89.1, 91.5 and 78.1%, respectively. Five of 80 samples (6.25%) from CA16infected patients were detected positive by ELISA with recombinant VP1 protein in which indicated the cross reactions and 0 of 5 samples from patients infected with other enteroviruses including CA4, CA5, CB3, CB5 and echovirus 6. Therefore, the recombinant VP1 protein of EV7l may provide a theoretical reference for establishing an effective antibody screening of IgM for EV71-infected patients with clinically suspected hand, foot, and mouth disease (HFMD).