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The dark side of T2: central nervous system lesions with low signal intensity on T2-weighted imaging T2 T T2weighted Tweighted weighted
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Carpentieri-Primo, Pedro

; Nahoum, Luiza

; Almeida, Louise

; Nacur, Fernando

; Alves Júnior, Sérgio Ferreira

; Ventura, Nina

Radiologia Brasileira

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2024, Volume 57 elocation e20230085en

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract The majority of central nervous system diseases show high signal intensity on T2-weighted magnetic resonance imaging. Diseases of the central nervous system with low signal intensity are less common, which makes it a finding that helps narrow the differential diagnosis. This was a retrospective analysis of brain and spine magnetic resonance imaging examinations in which that finding was helpful in the diagnostic investigation. We selected the cases of patients examined between 2015 and 2022. All diagnoses were confirmed on the basis of the clinical-radiological correlation or the histopathological findings. We obtained images of 14 patients with the following central nervous system diseases: arteriovenous malformation; cavernous malformation; metastasis from lymphoma; medulloblastoma; embryonal tumor; metastasis from melanoma; Rathke’s cleft cyst; Erdheim-Chester disease; aspergillosis; paracoccidioidomycosis; tuberculosis; syphilis; immunoglobulin G4-related disease; and metastasis from a pulmonary neuroendocrine tumor. We described lesions of different etiologies in which the T2-weighted imaging profile helped narrow the differential diagnosis and facilitated the definitive diagnosis. T2weighted Tweighted T2 weighted T common investigation 201 2022 clinicalradiological clinical radiological findings 1 malformation lymphoma medulloblastoma tumor melanoma Rathkes Rathke s cyst ErdheimChester Erdheim Chester disease aspergillosis paracoccidioidomycosis tuberculosis syphilis G4related Grelated G4 related G 20 202 2

Resumo A grande maioria das doenças do sistema nervoso central apresenta alto sinal em ponderações T2 na ressonância magnética. As alterações com baixo sinal são menos comuns, de forma que essa característica permite estreitar o diagnóstico diferencial. Analisamos, retrospectivamente, pacientes com imagens de ressonância magnética de crânio e/ou coluna em que este achado foi útil na investigação diagnóstica. Os pacientes foram selecionados no período entre 2015 e 2022 e todos tiveram seus diagnósticos confirmados por estudo clinicorradiológico ou por estudo histopatológico. Obtivemos imagens de 14 pacientes com as seguintes afecções: malformação arteriovenosa, cavernoma, metástase de linfoma, meduloblastoma, tumor embrionário, metástase de melanoma, cisto da bolsa de Rathke, doença de Erdheim-Chester, aspergilose, paracoccidioidomicose, tuberculose, sífilis, doença relacionada à IgG4 e metástase de tumor neuroendócrino de pulmão. Descrevemos lesões de diversas origens etiológicas que, a partir de suas características nas imagens ponderadas em T2, foi possível reduzir o quadro de diagnósticos diferenciais e chegar mais facilmente à hipótese final. T comuns diferencial Analisamos retrospectivamente eou diagnóstica 201 202 histopatológico 1 afecções arteriovenosa cavernoma linfoma meduloblastoma embrionário melanoma Rathke ErdheimChester, ErdheimChester Erdheim Chester, Chester Erdheim-Chester aspergilose paracoccidioidomicose tuberculose sífilis IgG pulmão final 20 2

https://doi.org/10.1590/0100-3984.2023.0085-en

JATROPHA MOLLISSIMA EXTRACT WITH CHITOSAN/COLLAGEN SCAFFOLDS AND THEIR BIODEGRADABILITY EVALUATION CHITOSANCOLLAGEN CHITOSAN COLLAGEN
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Gomes, Venturielso Ventura

; Azevedo, Ana Caroline Santana de

; Lima, Pedro Henrique Correia de

; Tavares, Albaniza Alves

; Fialho, Djair Araújo

; Sousa, Wladymyr Jefferson Bacalhau de

; Barbosa, Rossemberg C.

; Silva, Suédina Maria de Lima

; Fook, Marcus Vinicius Lia

Química Nova

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2024, Volume 47 Nº 3 elocation e-20230114

Resumo: En | Texto: En | PDF: En

Scaffolds are devices with interconnected pores that favor cell interaction and proliferation. They play a significant role in tissue engineering, as they mimic the conditions of tissue production in vivo. The aim of this study was to synthesize scaffolds of chitosan, collagen, and Jatropha mollissima by lyophilization and characterize their chemical/biodegradability and morphological properties. For that, techniques of optical microscopy, infrared spectrometry, biodegradation test, and degree of swelling were performed. A 2% (m/v) chitosan/collagen (1:9) in lactic acid solution was produced. Then, Jatropha mollissima crude extract was added to this solution in different proportions of mass (5, 10, and 15%). Optical microscope images indicated the three-dimensional network formation with interconnected pores and predominantly lamellar shape. Through infrared spectrometry, characteristic bands indicated a physical mixture. Also, the swelling degree of all samples was proportional to the amount of Jatropha mollissima extract with the highest percentage of 1852%. Biodegradation test also revealed a proportional ratio between the amount of sap used and the degraded percentage with the lowest value of around 35% in 28 days. In conclusion, it can be inferred that the scaffolds produced show potential to be used in tissue engineering as dressings. proliferation vivo chitosan collagen chemicalbiodegradability chemical biodegradability properties microscopy spectrometry performed 2 m/v mv m v (m/v chitosancollagen 19 1 9 (1:9 Then 5, 5 (5 10 15%. 15 15% . 15%) threedimensional three dimensional shape mixture Also 1852 1852% 35 days conclusion dressings (1: ( 185 3 (1 18

https://doi.org/10.21577/0100-4042.20230114

Pediatric kidney transplantation: outcomes with under and over 6-year-old donors transplantation 6yearold yearold 6 year old
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Lysakowski, Simone

; Garcia, Clotilde Druck

; Rohde, Roberta Weisheimer

; Vitola, Santo Pascual

; Pires, Fabian Silva

; Souza, Vandrea Carla de

; Ventura, Pedro Enrico

; Kist, Roger

Jornal de Pediatria

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2024, Volume 100 Nº 1 Páginas 67 - 73

Resumo: En | Texto: En | PDF: En

Abstract Objective Kidney shortage for pediatric kidney transplantation (PKT) entails the need to use low-weight and age donors, despite the apprehension. The aim of this study was to analyze the pediatric deceased donor kidney transplantations (pDDKT) outcomes in the first year after the procedure, stratified by donor age. Method Retrospective cohort of pDDKTs carried out between January 2013, and January 2018, at a PKT reference hospital in Southern Brazil. Donors were divided into group 1 (≤ 6 years), and group 2 (> 6 years); the analysis of the outcomes was carried out in the same period. Results There were 143 pDDKTs; 51 (35.66%) in group 1; and 92 (64.34%) in group 2. In both groups there were 17 graft losses (11.8%), with vascular thrombosis as the main cause (group 1: 5; group 2: 4). Among the complications, renal artery stenosis (RAS) with indication for angioplasty and stenting was more frequent in group 1 (7.8%; group 2: 2.2%). The 1-year Renal Transplant Recipients' and graft survival did not show significant differences between the groups, (p= = 0.95). However, the Glomerular Filtration Rate analysis was higher in group 2, reaching, in the 12th month, 79.3 mL/min/1,73m2, compared to 69.7 mL/min/1,73m2 in group 1(p= = 0.033). Conclusions Small donors can be considered for pDDKTs, as long as there is an expert team to perform the transplantation. (PKT lowweight low weight apprehension pDDKT (pDDKT procedure 2013 2018 Brazil ≤ ( years, years , years) > period 14 5 35.66% 3566 35 66 (35.66% 9 64.34% 6434 64 34 (64.34% 11.8%, 118 11.8% 11 8 (11.8%) 4. 4 . 4) complications RAS (RAS 7.8% 78 7 (7.8% 2.2%. 22 2.2% 2.2%) 1year Recipients p= p (p 0.95. 095 0.95 0 95 0.95) However reaching th month 793 79 3 79. mLmin173m2 mLminm mL min 73m2 m 697 69 69. mL/min/1,73m 1p= 1p 1(p 0.033. 0033 0.033 033 0.033) 201 35.66 356 (35.66 64.34 643 (64.34 11.8 (11.8% 7.8 (7.8 2.2 09 0.9 mLmin mLmin173m 73m 003 0.03 03 20 35.6 (35.6 64.3 (64.3 11. (11.8 7. (7. 0. 00 0.0 35. (35. 64. (64. (11. (7 (35 (64 (11 (3 (6 (1

https://doi.org/10.1016/j.jped.2023.07.005

Hypocitraturia as a biomarker of renal tubular acidosis in patients with Sjögren’s disease Sjögrens Sjögren s
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Coradin, Rafael

; Lopes, Maria Lúcia Lemos

; Goldani, João Carlos

; Ventura, Pedro Enrico

; Keitel, Elizete

Advances in Rheumatology

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2024, Volume 64 elocation 45

Resumo: En | Texto: En | PDF: En

Abstract Introduction Sjögren’s disease (SD) is an immune-mediated chronic inflammatory disease that affects epithelial tissues, mainly salivary and lacrimal glands. It also presents extraglandular manifestations. The main renal manifestation is tubulointerstitial nephritis (TIN), which can manifest as renal tubular acidosis (RTA). Urinary citrate may be a biomarker of RTA in these patients. The objective of this study was to evaluate whether hypocitraturia is a predictive biomarker of RTA in a sample of patients with SD in a tertiary hospital in southern Brazil. Methods All patients with SD who met the inclusion criteria and who participated in the rheumatology outpatient clinic of the Irmandade Santa Casa de Misericórdia de Porto Alegre were included. Demographic, SD, serological and urinary data were obtained. RTA was considered in those patients who persistently presented urinary pH above 5.5 and serum pH below 7.35. Patients who persistently had urinary pH above 5.5 underwent a urinary acidification test with furosemide and fludrocortisone. These patients received 1 mg of fludrocortisone and 40 mg of furosemide and had their urine samples tested 2, 4 and 6 h after taking the medications. The test was stopped at any urine sample with pH 5.5 or less. The variables were expressed as mean and standard deviation or interquartile range. The association between hypocitraturia and RTA was assessed using the chi-square. Results Forty-two patients were included, 95.2% female with a median age of 61.73 years. The prevalence of complete distal RTA was 4.88%. Twenty-eight patients underwent urine acidification testing. Five patients had hypocitraturia, and two of them had complete distal RTA. The association between hypocitraturia and RTA was statistically significant (p < 0.012), with a sensitivity of 100%, specificity of 91.2% and accuracy of 91.7%. The negative predictive value was 100%. The global renal assessment of the population demonstrated two patients with RTA, one patient with decreased renal function and six patients with proteinuria greater than 0.5 g/24 h. Conclusion The prevalence of RTA in the studied population was 4.88%. Hypocitraturia had high sensitivity and accuracy for the diagnosis of RTA. Sjögrens Sjögren s (SD immunemediated immune mediated tissues glands manifestations TIN, TIN , (TIN) . (RTA) Brazil included Demographic obtained 55 5 5. 735 7 35 7.35 2 medications less range chisquare. chisquare chi square. square chi-square Fortytwo Forty 952 95 95.2 6173 61 73 61.7 years 488 88 4.88% Twentyeight Twenty eight testing p 0.012, 0012 0.012 0 012 0.012) 100 100% 912 91 91.2 917 91.7% 05 0. g24 g 24 g/2 (TIN (RTA 3 7.3 9 95. 617 61. 48 8 4.88 001 0.01 01 10 91. 91.7 g2 g/ 7. 4.8 00 0.0 4.

https://doi.org/10.1186/s42358-024-00387-7

Traducción, adaptación cultural y validación de la Escala de Apoyo a Políticas Asociadas al Alcohol en universitarios mexicanos
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González-Angulo, Pedro

; Alonso-Castillo, María Magdalena

; García, Karla Selene López

; Ortiz-Rodríguez, Jeyle

; Ventura, Carla Aparecida Arena

Revista de Enfermagem Referência

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Dez 2023, Volume serVI Nº 2 elocation e22023

Resumo: En Pt Es | Texto: En Pt Es | PDF: En | PDF: Pt | PDF: Es

Abstract Background: Health protection through prevention and reduction of alcohol consumption is a public health priority. Some scales have been identified to assess public alcohol policies but in English language. Objective: To evaluate the psychometric properties of the translation and cultural adaptation of a scale to assess support for alcohol policies in young Mexican university students. Methodology: Methodological study, with the participation of 367 university students from southern Mexico. Construct validity was estimated by means of an exploratory factor analysis and the internal consistency of the questionnaire was checked to verify its reliability. Results: Internal consistency was 0.96. Construct validity was performed through exploratory factor analysis, identifying a three factors structure: harm reduction, marketing and information, and price and availability. Conclusion: The scale showed adequate reliability and validity, and can be applied in Spanish as an empirical indicator in studies concerning alcohol public policies in young university students.

Resumo Enquadramento: A proteção da saúde através da prevenção e redução do consumo de álcool é uma prioridade de saúde pública. Foram identificadas algumas escalas para avaliar as políticas públicas em matéria de álcool, mas em língua inglesa. Objetivo: Avaliar as propriedades psicométricas da tradução e adaptação cultural de uma escala para avaliar o apoio às políticas sobre o álcool em jovens estudantes universitários mexicanos. Metodologia: Estudo metodológico, com a participação de 367 estudantes universitários do sul do México. A validade do constructo foi estimada através de uma análise exploratória dos fatores e a consistência interna do questionário foi verificada para verificar a sua fiabilidade. Resultados: A consistência interna foi de 0,96. A validade de constructo foi realizada por médio de análise fatorial exploratória, identificando uma estrutura de três fatores: redução de danos, marketing e informação, e preço e disponibilidade. Conclusão: A escala mostrou fiabilidade e validade adequadas, e pode ser aplicada em espanhol como um indicador empírico em estudos relativos a políticas públicas sobre o álcool em jovens estudantes universitários.

Resumen Marco contextual: La protección de la salud por medio de la prevención y la reducción del consumo de alcohol es una prioridad para la salud pública. Se han identificado algunas escalas para evaluar políticas públicas de alcohol, pero en idioma inglés. Objetivo: Evaluar las propiedades psicométricas de la traducción y adaptación cultural de una escala para evaluar el apoyo a políticas de alcohol en jóvenes universitarios mexicanos. Metodología: Estudio metodológico, con la participación de 367 estudiantes universitarios del sur de México. La validez del constructo se estimó mediante un análisis factorial exploratorio y se verificó la consistencia interna del cuestionario para comprobar su fiabilidad. Resultados: La consistencia interna fue de 0.96. La validez de constructo se realizó mediante el análisis factorial exploratorio y se identificó una estructura de tres factores: la reducción del daño, el mercadeo e información, y el precio y la disponibilidad. Conclusión: La escala mostró fiabilidad y validez adecuada, y puede ser aplicada en español como indicador empírico en estudios referentes a las políticas públicas de alcohol en jóvenes universitarios.

https://doi.org/10.12707/rvi22023

Portuguese translation, cultural adaptation, and validation of the Person-Centred Practice Inventory - Staff (PCPI-S) translation adaptation PersonCentred Person Centred PCPIS PCPI S (PCPI-S
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Ventura, Filipa

; Costa, Paulo

; Chaplin, John

; Domingues, Inês

; Ferreira, Ricardo Jorge de Oliveira

; McCormack, Brendan

; Parreira, Pedro

; Sousa, Liliana B.

Ciência & Saúde Coletiva

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Nov 2023, Volume 28 Nº 11 Páginas 3347 - 3366

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Aiming to translate, culturally adapt, and psychometrically evaluate the Person-centred Practice Inventory - Staff (PCPI-S) for Portuguese healthcare professionals, this methodological study was conducted sequentially in two phases. Phase I followed the 10-steps recommendations from the ISPOR taskforce for translation and cultural adaptation of patient reported outcome measures. Phase II comprised a quantitative cross-sectional virtual survey of the translated PCPI-S with healthcare professionals, who were reached through snowball sampling from both primary and specialized care settings. The psychometric properties of the PCPI-S were determined by assessing reliability and construct validity. A sample of 304 healthcare professionals participated in Phase II. Ceiling effects were found. The overall internal consistency was excellent (> 0.9). The confirmatory factor analysis showed a good model fit after minor modifications, revealing construct validity, and supporting the theoretical framework. In conclusion, the three-factorial model of PCPI-S adjusted to the studied sample is a valid and reliable instrument to assess the perceptions of healthcare professionals on person-centred practice in various Portuguese clinical contexts. Considering the ceiling effects, the effect of social desirability should be explored. translate adapt Personcentred Person centred PCPIS PCPI S (PCPI-S phases 10steps steps 10 measures crosssectional cross sectional settings validity 30 found > ( 0.9. 09 0.9 . 0 9 0.9) modifications framework conclusion threefactorial three factorial personcentred person contexts explored 1 3 0.

Resumo Com o objetivo de traduzir, adaptar culturalmente e avaliar psicometricamente o Inventário para a Prática Centrada na Pessoa para profissionais de saúde (PCPI-S) em diversos contextos de prestação de cuidados, este estudo metodológico realizou-se em duas fases sequenciais. A Fase I seguiu as recomendações de dez etapas da taskforce da ISPOR para tradução e adaptação cultural de medidas de resultados auto reportados. A Fase II incluiu um estudo cross-sectional do PCPI-S traduzido com profissionais de saúde, que foram alcançados por meio de amostragem snowball em contextos de cuidados primários e diferenciados. A psicometria do PCPI-S foi analisada pela avaliação da confiabilidade e validade de construto. Uma amostra de 304 profissionais de saúde participou da Fase II. Efeitos de teto foram encontrados. A consistência interna geral foi excelente (> 0,9). A análise fatorial confirmatória mostrou um bom ajuste do modelo e validade de construto, refletindo o referencial teórico. Concluindo, o modelo tri-fatorial do PCPI-S ajustado à amostra estudada é um instrumento válido e fiável para avaliar as percepções dos profissionais de saúde sobre a prática centrada na pessoa em vários contextos de cuidados portugueses. Considerando os efeitos teto, a desejabilidade social deve ser explorada. traduzir PCPIS PCPI S (PCPI-S realizouse realizou se sequenciais reportados crosssectional cross sectional diferenciados construto 30 encontrados > ( 0,9. 09 0,9 . 0 9 0,9) teórico Concluindo trifatorial tri portugueses explorada 3 0,

https://doi.org/10.1590/1413-812320232811.17072022

Resiliência, depressão e autoeficácia entre profissionais de enfermagem brasileiros na pandemia de COVID-19 Resiliência COVID19 COVID 19 COVID-1 COVID1 1 COVID-
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Sousa, Laelson Rochelle Milanês

; Leoni, Pedro Henrique Tertuliano

; Carvalho, Raphael Augusto Gir de

; Ventura, Carla Aparecida Arena

; Silva, Ana Cristina de Oliveira e

; Reis, Renata Karina

; Gir, Elucir

Ciência & Saúde Coletiva

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Out 2023, Volume 28 Nº 10 Páginas 2941 - 2950

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract This aim of this study was to analyze levels of resilience, depression and self-efficacy among Brazilian nursing professionals during the COVID-19 pandemic. We conducted an analytical cross-sectional study between October and December 2020. Student’s t test, analysis of variance and multiple linear regression were used to investigate the impact of two main factors (Resilience and Self-efficacy) on depression. A total of 8,792 nursing professionals participated in the study; 5,124 (58.8%) had low levels of resilience. The mean overall score for Depression was 0.74, ranging from 0.59 to 0.80, while the mean overall score for Self-efficacy was 0.68, ranging from 0.56 to 0.80. The variable that had the strongest impact on depression levels was Resilience, explaining 6.6% of the outcome (p < 0.001, AdjustedR2 = 0.066). In general, respondents had low levels of resilience and self-efficacy and showed high mean depression scores. Level of resilience had an impact on depression. The findings reveal an urgent need for actions to promote the psychological health of nursing professionals working in crisis situations such as pandemics. selfefficacy self efficacy COVID19 COVID 19 COVID-1 pandemic crosssectional cross sectional 2020 Students Student s test Resilience Selfefficacy Self 8792 8 792 8,79 5124 5 124 5,12 58.8% 588 58 (58.8% 074 0 74 0.74 059 59 0.5 080 80 0.80 068 68 0.68 056 56 66 6 6.6 p 0001 001 0.001 AdjustedR 0.066. 0066 0.066 . 066 0.066) general scores pandemics COVID1 1 COVID- 202 879 79 8,7 512 12 5,1 58.8 (58.8 07 7 0.7 05 0. 08 0.8 06 0.6 6. 000 00 0.00 006 0.06 20 87 8, 51 5, 58. (58. 0.0 2 (58 (5 (

Resumo O objetivo deste artigo é analisar os níveis de resiliência, depressão e autoeficácia entre profissionais de enfermagem brasileiros na pandemia de COVID-19. Estudo transversal analítico realizado entre os meses de outubro e dezembro de 2020. Foram empregados o teste T de Student, a análise de variância e a regressão linear múltipla com o objetivo de investigar em que medida os dois grandes fatores (resiliência e autoeficácia) impactavam nos níveis de depressão. Participaram do estudo 8.792 profissionais de enfermagem, 5.124 (58,8%) tiveram baixos níveis de resiliência. A média da pontuação geral para “depressão” foi de 0,74 e variou de 0,59 a 0,80. A média da pontuação geral para “autoeficácia” foi de 0,68 e variou de 0,56 a 0,80. Quanto aos preditores de depressão, a variável que mais fortemente impactou os níveis de depressão foi resiliência, explicando 6,6% do desfecho (p < 0,001, R2 Ajustado = 0,066). Os participantes deste estudo tiveram, em geral, baixos níveis de resiliência e autoeficácia e maiores pontuações médias para depressão. Os níveis de resiliência impactaram a variável depressão. Urge a necessidade de ações voltadas para a promoção da saúde psicológica de profissionais de enfermagem inseridos em contextos pandêmicos. COVID19. COVID19 COVID 19. 19 COVID-19 2020 Student 8792 8 792 8.79 5124 5 124 5.12 58,8% 588 58 (58,8% “depressão 074 0 74 0,7 059 59 0,5 080 80 0,80 “autoeficácia 068 68 0,6 056 56 66 6 6,6 p 0001 001 0,001 R 0,066. 0066 0,066 . 066 0,066) pandêmicos COVID1 1 COVID-1 202 879 79 8.7 512 12 5.1 58,8 (58,8 07 7 0, 05 08 0,8 06 6, 000 00 0,00 006 0,06 COVID- 20 87 8. 51 5. 58, (58, 0,0 2 (58 (5 (

https://doi.org/10.1590/1413-812320232810.09852023

Resiliência, depressão e autoeficácia entre profissionais de enfermagem brasileiros na pandemia de COVID-19
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Sousa, Laelson Rochelle Milanês

; Leoni, Pedro Henrique Tertuliano

; Carvalho, Raphael Augusto Gir de

; Ventura, Carla Aparecida Arena

; Silva, Ana Cristina de Oliveira e

; Reis, Renata Karina

; Gir, Elucir

Ciência & Saúde Coletiva

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Out 2023, Volume 28 Nº 10 Páginas 2941 - 2950

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-812320232810.09852023

El concepto del estrés de aculturación desde la mirada del inmigrante hispano en los Estados Unidos
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Vásquez-Ventura, Ingrid Stephanie

; Guzmán-Ortiz, Elizabeth

; Rivera-Ramírez, Pedro Iván

; Fernández-Sánchez, Higinio

Index de Enfermería

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Jun 2023, Volume 32 Nº 2 elocation e14124

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Objective: Clarify the meaning of acculturation stress for the Hispanic immigrant, in addition to knowing each of the dimensions and characteristics of the concept, in order to better understand the needs of the immigrant living in the United States. Methods: The concept analysis was done through the eight steps proposed by Walker and Avant. Results: Three dimensions of the acculturation stress concept were identified: (1) personal stressors, (2) environmental stressors and (3) social stressors. Repentance, guilt, and denial were identified as antecedents in the concept. In general, the consequences are reflected in the mental health of the Hispanic immigrant. In addition, the measurement instruments that assess acculturation stress were recognized. Conclusions: A clear definition of the acculturation stress concept was obtained, which will help to estimate the construct validity of the measurements of this concept. The most frequently reported dimensions are considered in the stress inventory in Hispanics; however, it is recommended to analyze the construct validity of the concept. It would be important to consider the consequences derived from acculturation stress in the prevention and treatment of mental health.

Resumen Objetivo principal: Clarificar el significado de estrés de aculturación del inmigrante hispano, además de conocer cada una de las dimensiones y características propias del concepto, con la finalidad de comprender mejor las necesidades de la persona inmigrante que vive en los Estados Unidos. Metodología: El análisis de concepto se hizo a través de los ocho pasos propuestos por Walker y Avant. Resultados principales: Se identificaron tres dimensiones del concepto estrés de aculturación: (1) estresores personales, (2) estresores del entorno y (3) estresores sociales. Como antecedentes del concepto se identificó el arrepentimiento, la culpa y negación. En general, las consecuencias se reflejan en la salud mental del inmigrante hispano. Además, se reconoció los instrumentos de medición que evalúan el estrés de aculturación. Conclusión principal: Se obtuvo una definición clara del concepto estrés de aculturación desde la perspectiva del inmigrante hispano, que ayudará a estimar la validez de constructo de las mediciones de este concepto. Las dimensiones reportadas con mayor frecuencia son consideradas en el inventario de estrés en hispanos, sin embargo, se recomienda analizar la validez de constructo del concepto. Sería importante considerar las consecuencias derivadas del estrés de aculturación en la prevención y tratamiento de la salud mental.

https://doi.org/10.58807/indexenferm20235796

10.

The Contribution of Meteorological Parameters and the COVID-19 Partial Lockdown on Air Quality in Rio de Janeiro, Brazil COVID19 COVID 19 COVID-1 Janeiro COVID1 1 COVID-
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Beringui, Karmel

; Justo, Elizanne P. S.

; Ventura, Luciana M. B.

; Gomes, Ruan G. S.

; Lionel-Mateus, Vinícius

; Cruz, Alex H. De La

; Almeida, Ana Carolina L. B. de

; Ramos, Michelle B.

; Suazo, Julio Angeles

; Valle, Pedro H. R.

; Gioda, Adriana

Journal of the Brazilian Chemical Society

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Jan 2023, Volume 34 Nº 1 Páginas 69 - 82

Resumo: En | Texto: En | PDF: En

This study evaluated the pollutant levels (NO2, SO2, CO, and O3), air quality index (AQI) and the influence of meteorological variables and coronavirus disease (COVID-19) pandemic on the air quality in Rio de Janeiro. The data set used comprises periods before (March-April, 2019) and during pandemic (March-April, 2020). According to the AQI results, on most days, the air quality was ranked as “good”. Brazilian air quality standards for SO2, O3, and NO2 were not exceeded in any of the monitoring stations during partial lockdown, while CO exceeded in all periods in one site due to industrial emission. Comparing both periods, descriptive statistics for the meteorological parameters presented no differences, which suggests similar conditions. However, when evaluated week by week in 2020, weather conditions presented some differences that probably affected pollutant concentrations. The correlations between O3 and NO2 and some meteorological parameters indicate that variations in both favored ozone formation, since it is a photochemical process favored by temperature and solar radiation and that, in Rio de Janeiro, low NO2 concentrations lead to increased O3. The improvements on air quality during the partial lockdown may be attributed mainly to a reduction on emission sources rather than weather conditions. NO2, NO (NO2 SO2 SO O , O3) (AQI COVID19 COVID 19 (COVID-19 Janeiro MarchApril, MarchApril March April, April (March-April 2019 2020. 2020 . 2020) results days good. good “good” However formation (NO COVID1 1 (COVID-1 201 202 “good (COVID- 20 (COVID 2

https://doi.org/10.21577/0103-5053.20220089

11.

Evaluation of tumor load in sentinel lymph node in patients with cutaneous melanoma
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ALMEIDA, PEDRO DEAK DE

; LAVAREZE, LUCCAS

; RANGEL, CAROLINA EMERICK DA SILVA

; MARIANO, FERNANDA VIVIANE

; RODRIGUES, DIEGO VICTOR NUNES

; BALDASSO, TIAGO ANTONIO

; FANNI, RENATO VENTURA

; CASARIM, ANDRE LUIS MAION

; NEGRO, ANDRÉ DEL

; TINCANI, ALFIO JOSÉ

Revista do Colégio Brasileiro de Cirurgiões

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2023, Volume 50 elocation e20233521

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Introduction: cutaneous melanoma (MC) is a malignant neoplasm derived from melanocytic cells with an aggressive behavior. It is usually associated with the multifactorial interaction of genetic susceptibility and environmental exposure, usually ultraviolet radiation. Despite advances in treatment, the disease remains relentless with poor prognosis. Sentinel lymph node (SLN) biopsy is a technique used to screen patients in need of lymph node dissection. Objectives: to correlate the tumor burden in the SLN with the mortality of patients undergoing SLN biopsy. Methodology: the medical records and histological slides of patients with MC who underwent SLN biopsy treated at HC-Unicamp from 2001 to 2021 were retrospectively analyzed. The positive SLN were measured according to the size of the tumor infiltration area, for analysis of the depth of invasion (DI), closest proximity to the capsule (CPC) and tumor burden (TB). For statistical analysis, associations between variables were analyzed using Fishers exact test, with post Bonferroni test and Wilcoxon test. Results: 105 records of patients who underwent SLN biopsy of MC were identified. Of these, nine (8.6%) had positive SLN and 81 (77.1%) had negative SLN. The performed lymphadenectomies resulted in 55.6% (n=5) affected, 22.2% (n=2) without disease and 22.2% (n=2) were not performed. Mean CPC, TB, and DI were 0.14mm, 32.10mm and 2.33mm, respectively. Patients with T2 and T3 tumors were more likely to show the SLN affected (p=0.022). No patient with positive SLN died during follow-up. Conclusion: patients who presented T3 staging are the ones who most presented positive SLN. Introduction (MC behavior exposure radiation treatment prognosis (SLN dissection Objectives Methodology HCUnicamp HC Unicamp 200 202 area DI, , (DI) CPC (CPC TB. TB . (TB) Results 10 identified these 8.6% 86 8 6 (8.6% 77.1% 771 77 1 (77.1% 556 55 55.6 n=5 n5 n 5 (n=5 222 22 2 22.2 n=2 n2 (n=2 014mm mm 0 14mm 0.14mm 3210mm 32 10mm 233mm 33mm 2.33mm respectively T p=0.022. p0022 p p=0.022 022 (p=0.022) followup. followup follow up. up follow-up Conclusion 20 (DI (TB 8.6 (8.6 77.1 7 (77.1 55. n= (n= 22. 3 p002 p=0.02 02 (p=0.022 8. (8. 77. (77. (n p00 p=0.0 (p=0.02 (8 (77 p0 p=0. (p=0.0 ( (7 p=0 (p=0. p= (p=0 (p= (p

RESUMO Introdução: o melanoma cutâneo (MC) é uma neoplasia maligna de comportamento agressivo, derivada das células melanocíticas, geralmente causado pela associação de interação da suscetibilidade genética e a exposição ambiental. A biópsia do linfonodo sentinela (LNS) é um procedimento utilizado para rastreamento de doentes com necessidade ou não de linfadenectomia, diminuindo a exposição do paciente a cirurgias maiores. Objetivos: correlacionar a carga do tumor no LNS com a mortalidade de pacientes com MC. Métodos: foram examinados retrospectivamente prontuários e lâminas histológicas de doentes com MC submetidos a biópsia de LNS atendidos no HC-Unicamp entre o período compreendido de 2001 a 2021. Os LNS positivos foram mensurados quanto ao tamanho da área de infiltração do tumor, para análise da profundidade de invasão (PI), menor proximidade com a cápsula (MPC) e carga do tumor (CT). As associações entre as variáveis foram analisadas pelo teste Exato de Fisher, com pós teste de Bonferroni e Wilcoxon. Resultados: foram identificados 105 pacientes com biópsia de LNS, sendo nove (8,6%) casos com LNS positivo. A média de MDC, CT e PI foram 0,14 mm, 32,10 mm, e 2,33 mm, respectivamente. Doentes com tumores T2 e T3 apresentaram maior chance de acometimento do LNS (p=0,022). Nenhum paciente com LNS positivo foi a óbito durante o acompanhamento. Conclusão: doentes que apresentaram tumores maiores (T2 e T3) apresentaram maior chance de linfonodos sentinelas positivos. Além do tamanho do tumor, a presença de maior carga do tumor demonstrou que os mesmos podem ser beneficiados pela biópsia de LNS. Introdução (MC agressivo melanocíticas ambiental (LNS linfadenectomia Objetivos Métodos HCUnicamp HC Unicamp 200 2021 PI, , (PI) MPC (MPC CT. . (CT) Fisher Wilcoxon Resultados 10 8,6% 86 8 6 (8,6% MDC 014 0 14 0,1 mm 3210 32 32,1 233 2 33 2,3 respectivamente T p=0,022. p0022 p p=0,022 022 (p=0,022) acompanhamento Conclusão (T 20 202 (PI (CT 1 8,6 (8,6 01 0, 321 3 32, 23 2, p002 p=0,02 02 (p=0,022 8, (8, p00 p=0,0 (p=0,02 (8 p0 p=0, (p=0,0 ( p=0 (p=0, p= (p=0 (p= (p

https://doi.org/10.1590/0100-6991e-20233521-en

12.

Real-world effectiveness and safety of direct-acting antivirals for the treatment of hepatitis C virus in kidney and liver transplant recipients: experience of a large transplant center in Brazil Realworld Real world directacting direct acting recipients
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Pacheco, Larissa Sgaria

; Ventura, Pedro Enrico

; Kist, Roger

; Garcia, Valter Duro

; Meinerz, Gisele

; Tovo, Cristiane Valle

; Cantisani, Guido Pio Cracco

; Zanotelli, Maria Lucia

; Mucenic, Marcos

; Keitel, Elizete

Revista do Instituto de Medicina Tropical de São Paulo

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2023, Volume 65 elocation e59

Resumo: En | Texto: En | PDF: En

ABSTRACT Direct-acting antivirals are the gold-standard treatment for chronic HCV infections, but few studies have investigated their use on kidney and liver transplant recipients. We conducted a real-world study to evaluate the rates of sustained virological response with direct-acting antivirals in kidney and liver transplant recipients. Moreover, it also aimed to evaluate direct-acting antivirals (DAAs) interference with immunosuppressant levels and to describe the frequency of adverse events. As part of this retrospective observational cohort, we included adult patients that had undergone a kidney transplant (KT) or liver transplant (LT) at our center, had a chronic HCV infection, and were treated with DAAs from June 2016 to December 2021. A total of 165 patients were included in the analysis, divided in 108 KT and 57 LT recipients. HCV genotype 1 was more frequent in KT (58.4%), and genotype 3 was more prevalent in LT (57.9%) patients. Sustained virological response was achieved in 89.6% of patients. Adverse effects were reported by 36% of patients. There were significant interactions with immunosuppressants requiring dose adjustments. A total of three episodes of rejection were reported in KT recipients. In conclusion, DAA treatment resulted in high rates of SVR and was well tolerated in both kidney and liver transplant patients. Adverse events were frequent but not severe in most patients, with low treatment drop-out rates. Interactions with immunosuppressants need monitoring since dose adjustments may be required. Reporting real-life experiences is important to help build evidence for patient management in non-controlled environments. Directacting Direct acting goldstandard gold standard infections recipients realworld real world directacting direct Moreover (DAAs cohort (KT (LT center infection 201 2021 16 analysis 10 5 58.4%, 584 58.4% , 58 4 (58.4%) 57.9% 579 9 (57.9% 896 89 6 89.6 36 conclusion dropout drop out required reallife life noncontrolled non controlled environments 20 202 58.4 (58.4% 57.9 (57.9 8 89. 2 58. (58.4 57. (57. (58. (57 (58 (5 (

https://doi.org/10.1590/s1678-9946202365059

13.

Portuguese translation, cultural adaptation, and validation of the Person-Centred Practice Inventory - Staff (PCPI-S)
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Ventura, Filipa

; Costa, Paulo

; Chaplin, John

; Domingues, Inês

; Ferreira, Ricardo Jorge de Oliveira

; McCormack, Brendan

; Parreira, Pedro

; Sousa, Liliana B.

Ciência & Saúde Coletiva

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2023, Volume 28 Nº 11 Páginas 3347 - 3366

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-812320232811.17072022

14.

O que mudou entre os períodos de pico e de platô durante a primeira onda do SARS-CoV-2? Estudo multicêntrico português em unidades de cuidados intensivos SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV-2 SARS-CoV- SARS-CoV
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Pereira, Rui Antunes

; Sousa, Marta

; Cidade, José Pedro

; Melo, Luís

; Lopes, Diogo

; Ventura, Sara

; Aragão, Irene

; Lima Neto, Raul Miguel de Freitas

; Molinos, Elena

; Marques, Ana

; Cardoso, Nelson

; Marino, Flávio

; Monteiro, Filipa Brás

; Oliveira, Ana Pinho

; Silva, Rogério C

; Real, André Miguel Neto

; Banheiro, Bruno Sarmento

; Reis, Renato

; Adão-Serrano, Maria

; Cracium, Ana

; Valadas, Ana

; Ribeiro, João Miguel

; Póvoa, Pedro

; Tapadinhas, Camila

; Mendes, Vítor

; Coelho, Luís

; Maia, Raquel

; Freitas, Paulo Telles

; Ferreira, Isabel Amorim

; Ramires, Tiago

; Val-Flores, Luís Silva

; Cascão, Mariana

; Alves, Rita

; Rodeia, Simão C

; Barrigoto, Cleide

; Cardiga, Rosa

; Silva, Maria João Ferreira da

; Vale, Bruno

; Fonseca, Tatiana

; Rios, Ana Lúcia

; Camões, João

; Pérez, Danay

; Cabral, Susana

; Ribeiro, Maria Inês

; Mendes, João João

; Gouveia, João

; Fernandes, Susana Mendes

Revista Brasileira de Terapia Intensiva

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Dez 2022, Volume 34 Nº 4 Páginas 433 - 442

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To analyze and compare COVID-19 patient characteristics, clinical management and outcomes between the peak and plateau periods of the first pandemic wave in Portugal. Methods: This was a multicentric ambispective cohort study including consecutive severe COVID-19 patients between March and August 2020 from 16 Portuguese intensive care units. The peak and plateau periods, respectively, weeks 10 - 16 and 17 - 34, were defined. Results: Five hundred forty-one adult patients with a median age of 65 [57 - 74] years, mostly male (71.2%), were included. There were no significant differences in median age (p = 0.3), Simplified Acute Physiology Score II (40 versus 39; p = 0.8), partial arterial oxygen pressure/fraction of inspired oxygen ratio (139 versus 136; p = 0.6), antibiotic therapy (57% versus 64%; p = 0.2) at admission, or 28-day mortality (24.4% versus 22.8%; p = 0.7) between the peak and plateau periods. During the peak period, patients had fewer comorbidities (1 [0 - 3] versus 2 [0 - 5]; p = 0.002) and presented a higher use of vasopressors (47% versus 36%; p < 0.001) and invasive mechanical ventilation (58.1 versus 49.2%; p < 0.001) at admission, prone positioning (45% versus 36%; p = 0.04), and hydroxychloroquine (59% versus 10%; p < 0.001) and lopinavir/ritonavir (41% versus 10%; p < 0.001) prescriptions. However, a greater use of high-flow nasal cannulas (5% versus 16%, p < 0.001) on admission, remdesivir (0.3% versus 15%; p < 0.001) and corticosteroid (29% versus 52%, p < 0.001) therapy, and a shorter ICU length of stay (12 days versus 8, p < 0.001) were observed during the plateau. Conclusion: There were significant changes in patient comorbidities, intensive care unit therapies and length of stay between the peak and plateau periods of the first COVID-19 wave. Objective COVID19 COVID 19 COVID-1 characteristics Portugal Methods 202 1 units respectively 34 defined Results fortyone forty one 6 57 [5 74 years 71.2%, 712 71.2% , 71 (71.2%) included 0.3, 03 0.3 0 3 0.3) 40 (4 39 0.8, 08 0.8 8 0.8) pressurefraction pressure fraction 139 (13 136 0.6, 06 0.6 0.6) 57% (57 64% 64 0.2 02 admission 28day day 28 24.4% 244 24 4 (24.4 22.8% 228 22 0.7 07 7 period ( [ 5 5] 0.002 0002 002 47% 47 (47 36% 36 0.001 0001 001 58.1 581 58 (58. 49.2% 492 49 45% 45 (45 0.04, 004 0.04 04 0.04) 59% 59 (59 10% lopinavirritonavir lopinavir ritonavir 41% 41 (41 prescriptions However highflow high flow 5% (5 16% 0.3% (0.3 15% 15 29% 29 (29 52 52% 12 Conclusion COVID1 COVID- 20 71.2 (71.2% 0. 13 24.4 (24. 22.8 0.00 000 00 58. (58 49.2 0.0 (0. (2 71. (71.2 24. (24 22. 49. (0 (71. (71 (7

RESUMO Objetivo: Analisar e comparar as características de pacientes críticos com a COVID-19, a abordagem clínica e os resultados entre os períodos de pico e de platô na primeira onda pandêmica em Portugal. Métodos: Este foi um estudo de coorte multicêntrico ambispectivo, que incluiu pacientes consecutivos com a forma grave da COVID-19 entre março e agosto de 2020 de 16 unidades de terapia intensiva portuguesas. Definiram-se as semanas 10 - 16 e 17 - 34 como os períodos de pico e platô. Resultados: Incluíram-se 541 pacientes adultos com mediana de idade de 65 [57 - 74] anos, a maioria do sexo masculino (71,2%). Não houve diferenças significativas na mediana de idade (p = 0,3), no Simplified Acute Physiology Score II (40 versus 39; p = 0,8), na pressão parcial de oxigênio/fração inspirada de oxigênio (139 versus 136; p = 0,6), na terapia com antibióticos na admissão (57% versus 64%; p = 0,2) ou na mortalidade aos 28 dias (24,4% versus 22,8%; p = 0,7) entre o período de pico e platô. Durante o período de pico, os pacientes tiveram menos comorbidades (1 [0 - 3] versus 2 [0 - 5]; p = 0,002); fizeram mais uso de vasopressores (47% versus 36%; p < 0,001) e ventilação mecânica invasiva na admissão (58,1% versus 49,2%; p < 0,001), e tiveram mais prescrição de hidroxicloroquina (59% versus 10%; p < 0,001), lopinavir/ritonavir (41% versus 10%; p < 0,001) e posição prona (45% versus 36%; p = 0,04). Entretanto, durante o platô, observou-se maior uso de cânulas nasais de alto fluxo (5% versus 16%; p < 0,001) na admissão, remdesivir (0,3% versus 15%; p < 0,001) e corticosteroides (29% versus 52%; p < 0,001), além de menor tempo de internação na unidade de terapia intensiva (12 versus 8 dias; p < 0,001). Conclusão: Houve mudanças significativas nas comorbidades dos pacientes, nos tratamentos da unidade de terapia intensiva e no tempo de internação entre os períodos de pico e platô na primeira onda da COVID-19. Objetivo COVID19, COVID19 COVID 19, 19 Portugal Métodos ambispectivo COVID-1 202 1 portuguesas Definiramse Definiram se 3 Resultados Incluíramse Incluíram 54 6 57 [5 74 anos 71,2%. 712 71,2% . 71 (71,2%) 0,3, 03 0,3 , 0 0,3) 40 (4 39 0,8, 08 0,8 0,8) oxigêniofração fração 139 (13 136 0,6, 06 0,6 0,6) 57% (57 64% 64 0,2 02 24,4% 244 24 4 (24,4 22,8% 228 22 0,7 07 7 ( [ 5 5] 0,002 0002 002 0,002) 47% 47 (47 36% 36 0,001 0001 001 58,1% 581 58 (58,1 49,2% 492 49 0,001, 59% 59 (59 10% lopinavirritonavir lopinavir ritonavir 41% 41 (41 45% 45 (45 0,04. 004 0,04 04 0,04) Entretanto observouse observou 5% (5 16% 0,3% (0,3 15% 15 29% 29 (29 52% 52 12 0,001. Conclusão COVID19. 19. COVID1 COVID- 20 71,2 (71,2% 0, 13 24,4 (24, 22,8 0,00 000 00 58,1 (58, 49,2 0,0 (0, (2 71, (71,2 24, (24 22, 58, (58 49, (0 (71, (71 (7

https://doi.org/10.5935/0103-507x.20210037-pt

15.

Migración de retorno en Latinoamérica y el Caribe: Una revisión sistemática exploratoria
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Fernández-Sánchez, Higinio

; Vásquez-Ventura, Ingrid Stephanie

; Rivera-Ramírez, Pedro Iván

; Zahoui, Ziad

Migraciones internacionales

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Dez 2022, Volume 13 elocation rmiv1i12431

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen El artículo determina el alcance y la naturaleza de la evidencia empírica es decir artículos académicos referentes a los migrantes que regresan a países en Latinoamérica y el Caribe. Mediante la metodología de las Revisiones Sistemáticas Exploratorias, se incluyeron 23 estudios empíricos publicados en revistas indexadas los datos se sintetizaron mediante estadística descriptiva y análisis de contenido convencional. En su mayoría, los participantes son migrantes originarios de México (n=19), y el país desde el cual retornan es Estados Unidos (n=20). Se identificaron cuatro categorías emergentes: a) salud y bienestar, b) contexto social, político y cultural, c) adicciones y d) motivos de retorno. El fenómeno en estudio muestra innovación debido a la limitada literatura científica que analiza la migración de retorno. Se concluye que las personas que regresan a sus lugares de origen se enfrentan a situaciones desfavorables económicas, políticas y de salud.

Abstract The following article determines the scope and nature of the empirical evidence on migrants returning to Latin American and Caribbean countries. Following the scoping review methodology, 23 empirical studies published in indexed journals were included. The data were synthesized using descriptive statistics and conventional content analysis. Most of the participants are migrants from Mexico (n=19) and the return country is the United States (n=20). Four emerging categories were identified: a) health and well-being, b) social, political, and cultural context, c) addictions, and d) reasons for return. The phenomenon under study shows innovation due to the limited scientific literature that analyzes return migration. It is concluded that people returning to their places of origin face unfavorable economic, political, and health situations.

https://doi.org/10.33679/rmi.v1i1.2431 11 downloads

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