Resumen La bacteria Escherichia coli causa la colibacilosis en animales de granja que actúan como reservorios de cepas patógenas. La resistencia antimicrobiana de E. coli productor de betalactamasas de espectro extendido [BLEE] es un grave problema de salud pública y se puede atribuir a factores relacionados con el consumo de alimentos y el contacto con animales domésticos. El objetivo de este estudio fue determinar la presencia y patrones de resistencia antimicrobiana de E. coli BLEE aislado en muestras fecales provenientes de bovinos productores de leche de la provincia de Pichincha. Se analizaron un total 182 muestras de heces de bovinos: 112 muestras de bovinos faenados en el Camal Metropolitano de la provincia de Pichincha y 70 muestras de la colección de la Unidad de Investigación de Enfermedades Transmitidas por Alimentos y Resistencias a los Antimicrobianos [UNIETAR], se realizó el aislamiento de E. coli BLEE, la identificación bioquímica y pruebas de resistencia a los principales antibióticos utilizados. Se logró identificar 93 muestras positivas a E. coli BLEE (51 %), el análisis fenotípico reveló que los antibióticos amoxicilina más ácido clavulánico, cefepime, ceftazidima, ciprofloxacina, amikacina y tetraciclina presentaron porcentajes de resistencia mayores al 80 %. Además, se observó una baja resistencia a la nitrofurantoína, cefoxitin y ertapenem, mientras que ningún aislado fue resistente a la tigeciclina. El 100 % de los aislados presentaron fenotipos de multirresistencia y el patrón más frecuente estuvo compuesto por 7 familias de antibióticos. En conclusión, estos resultados sugieren que E. coli originaria de bovinos lecheros podría ser un reservorio de genes BLEE.

Abstract Escherichia coli causes colibacillosis in farm animals that act as reservoirs for pathogenic strains. Antimicrobial resistance of E. coli producing Extended Spectrum Beta-lactamases [ESBL] is a serious public health problem that can be attributed to factors related to food consumption and contact with domestic animals. This study aimed to determine the presence and patterns of antimicrobial resistance of ESBL E. coli isolated from fecal samples from dairy cattle in the Pichincha province. A total of 182 bovine feces samples were analyzed, 112 samples from cattle slaughtered at the official slaughterhouse in Quito-Pichincha province, and 70 samples from the collection of the Foodborne Diseases and Antimicrobial Resistance Research Unit [UNIETAR]. The isolation of ESBL E. coli, biochemical identification, and resistance tests using the main antibiotics were carried out at UNIETAR. It was possible to identify 93 positive samples for ESBL E. coli (51%), phenotypic analysis revealed that antibiotics such as amoxicillin plus clavulanic acid, cefepime, ceftazidime, ciprofloxacin, amikacin, tetracycline, presented resistance higher than 80%. Furthermore, low resistance to nitrofurantoin, cefoxitin, and ertapenem was observed, while no isolate was resistant to tigecycline. One hundred percent of the isolates presented multi-resistance phenotypes, with the most frequent pattern being composed of 7 families of antibiotics. In conclusion, these results suggest that E. coli from dairy cattle origin could be an important reservoir of ESBL genes.

Resumo Objetivo: Analisar as propriedades psicométricas da Escala de Resiliência Wagnild e Young, versão argentina, em um grupo de pessoas idosas costarriquenhas. Materiais e métodos: Um grupo piloto (N = 40, X = 69,38) e outro grupo para a análise das propriedades psicométricas (N = 100, X = 69,31) foram utilizados. A Escala de Resiliência Wagnild e Young, versão argentina, com 25 itens, foi utilizada. Para estabelecer a escala a ser validada, foi realizada uma análise de julgamento por especialistas e um estudo piloto, após o qual foi realizado o estudo de validação completo. A análise fatorial e o alfa de Cronbach foram aplicados. Resultados: A análise fatorial extraiu dois fatores: a) “capacidade de autoeficácia” e b) “capacidade de propósito e significado na vida”. A consistência interna ao nível global foi de 0,84 (21 itens); para o primeiro fator foi de 0,81 e para o segundo fator foi de 0,74. Conclusões: O instrumento é confiável e válido para avaliar níveis de resiliência a partir de uma perspectiva holística e interdisciplinar em uma população de idosos com características semelhantes às da amostra estudada. Recomendam-se futuras análises qualitativas para melhor delimitar as construções com base nas características da população.

Abstract Purpose: To analyze the psychometric characteristics of the Wagnild and Young Resilience Scale Argentine version in a Costa Rican elderly group. Materials and methods: The study had two groups, one for the pilot study (N = 40, X = 69.38), and another for the analysis of the psychometric properties (N = 100, X = 69.31). The 25-item Wagnild and Young Resilience Scale, Argentine version, was used. An analysis by expert judgment and a pilot study were carried out to establish the scale to be validated, after which, the complete validation study was carried out. Factor analyzes and Cronbach’s alpha were applied. Results: They were obtained two factors named: a) “selfefficacy capacity”, and b) “purpose in life capacity”. The global internal consistency was 0.84, for the first factor was 0.81 and for the second factor was 0.74. Conclusions: The scale generated is reliable and valid to assess resilience in an elderly people with similar characteristics to the present study. In the future, it is recommended to carry out qualitative analyzes to better define the constructs based on the characteristics of the population.

Resumen Objetivo: Analizar las propiedades psicométricas de la escala de resiliencia de Wagnild y Young, versión argentina, en un grupo de personas adultas mayores costarricenses. Materiales y métodos: Se contó con un grupo piloto (N = 40, X = 69.38) y otro para el análisis de las propiedades psicométricas (N = 100, X = 69.31). Se utilizó la escala de resiliencia de Wagnild y Young, versión argentina, de 25 ítems. Se efectuó un análisis por juicio de personas expertas y un estudio piloto, para establecer la escala por validar; posterior a esto, se realizó el estudio de validación completo. Se aplicaron análisis factoriales y alfa de Cronbach. Resultados: El análisis factorial extrajo dos factores denominados: a) “capacidad de autoeficacia” y b) “capacidad de propósito y sentido de vida”. La consistencia interna en el nivel global fue 0.84 (21 ítems); para el primer factor, 0.81, y para el segundo factor, 0.74. Conclusiones: El instrumento es confiable y válido para valorar los niveles de resiliencia desde una óptica integral e interdisciplinaria, en una población de personas adultas mayores con las características similares a las de la muestra estudiada. A futuro, se recomienda realizar análisis cualitativos para delimitar mejor los constructos, con base en las características de la población.

Abstract: In this paper, we present an in-depth analysis leveraging several renowned machine learning techniques, including Snap Random Forest, XGBoost, Extra Trees, and Snap Decision Trees, to characterize comorbidity factors influencing the Mexican population. Distinct from existing literature, our study undertakes a comprehensive exploration of algorithms within a defined search space, conducting experiments ranging from coarse to fine granularity. This approach, coupled with machine learning-driven feature enhancement, enables us to deeply characterize the factors most significantly affecting COVID-19 mortality rates within the Mexican demographic. Contrary to other studies, which obscure the identification of primary factors for local populations, our findings reveal that geographical factors such as residence location hold greater significance than even comorbidities, indicating that socioeconomic factors play a pivotal role in the survival outcomes of the Mexican population. This research not only contributes to the targeted understanding of COVID-19 mortality drivers in Mexico but also highlights the critical influence of socioeconomic determinants, offering valuable insights for public health strategies and policy formulation.

ABSTRACT Objective: This study aimed to compare the insertion torque (IT), flexural strength (FS) and surface alterations between stainless steel (SS-MIs) and titanium alloy (Ti-MIs) orthodontic mini-implants. Methods: Twenty-four MIs (2 x 10 mm; SS-MIs, n = 12; Ti-MIs, n = 12) were inserted on artificial bone blocks of 20 lb/ft3 (20 PCF) and 40 lb/ft3 (40 PCF) density. The maximum IT was recorded using a digital torque meter. FS was evaluated at 2, 3 and 4 mm-deflection. Surface topography and chemical composition of MIs were assessed by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). General linear and mixed models were used to assess the effect of the MI type, bone density and deflection on the evaluated outcomes. Results: The IT of Ti-MIs was 1.1 Ncm greater than that obtained for the SS-MIs (p= 0.018). The IT for MIs inserted in 40 PCF test blocks was 5.4 Ncm greater than that for those inserted in 20 PCF test blocks (p < 0.001). SS-MIs inserted in higher density bone (40 PCF) had significantly higher flexural strength than the other groups, at 2 mm (98.7 ± 5.1 Ncm), 3 mm (112.0 ± 3.9 Ncm) and 4 mm (120.0 ± 3.4 Ncm) of deflection (p< 0.001). SEM evidenced fractures in the Ti-MIs. EDS revealed incorporation of 18% of C and 2.06% of O in the loaded SS-MIs, and 3.91% of C in the loaded Ti-MIs. Conclusions: Based on the findings of this in vitro study, it seems that SS-MIs offer sufficient stability and exhibit greater mechanical strength, compared to Ti-MIs when inserted into higher density bone. Objective IT, , (IT) (FS SSMIs SS (SS-MIs TiMIs Ti (Ti-MIs miniimplants. miniimplants mini implants. implants mini-implants Methods Twentyfour Twenty four ( 1 SSMIs, MIs, 12 TiMIs, lbft3 lbft lb ft3 ft lb/ft (4 meter mmdeflection. mmdeflection deflection. mm-deflection (SEM Xray X ray EDS. . (EDS) type outcomes Results 11 1. p= p 0.018. 0018 0.018 0 018 0.018) 54 5 5. 0.001. 0001 0.001 001 0.001) groups 98.7 987 98 7 (98. 51 Ncm, 112.0 1120 112 (112. 39 9 3. 120.0 1200 120 (120. 34 p< TiMIs. MIs. 18 206 06 2.06 391 91 3.91 Conclusions (IT (EDS 0.01 01 000 0.00 00 98. (98 112. (112 120. (120 2.0 0.0 (9 (11 (12 2. 0. (1

RESUMO Objetivo: O objetivo deste estudo foi comparar o torque de inserção (TI), a resistência flexural (RF) e as alterações de superfície em mini-implantes ortodônticos de aço inoxidável (MIs-Ai) e de liga de titânio (MIs-Ti). Métodos: Vinte e quatro MIs (2 x 10 mm; MIs-Ai, n = 12; MIs-Ti, n = 12) foram inseridos em blocos de osso artificial de densidades de 20 lb/ft3 (20 PCF) e 40 lb/ft3 (40 PCF). O torque máximo de inserção foi registrado por meio de um torquímetro digital. A resistência flexural foi avaliada nas deflexões de 2, 3 e 4 mm. Topografia de superfície e composição química dos MIs foram avaliadas por Microscopia Eletrônica de Varredura (MEV) e Espectroscopia de Energia Dispersiva de Raios X (EDS). Modelos lineares gerais e mistos foram utilizados para avaliar o efeito do tipo de MI, da densidade óssea e da deflexão nos desfechos avaliados. Resultados: O TI dos MIs-Ti foi 1,1 Ncm maior do que o obtido para os MIs-Ai (P = 0,018). O TI para MIs inseridos em blocos de teste de 40 PCF foi 5,4 Ncm maior do que para aqueles inseridos em blocos de teste 20 PCF (p < 0,001). MIs-Ai inseridos em osso de maior densidade (40 PCF) apresentaram resistência flexural significativamente maior do que outros grupos, em deflexões de 2 mm (98,7 ± 5,1 Ncm), 3 mm (112,0 ± 3,9 Ncm) e 4 mm (120,0 ± 3,4 Ncm) (p < 0,001). A MEV evidenciou fraturas nos MIs-Ti. A EDS revelou incorporação de 18% de C e 2,06% de O nos MIs-Ai e 3,91% de C nos MIs-Ti, ambos submetidos a testes mecânicos. Conclusões: Com base nos resultados desse estudo in vitro, os MIs-Ai aparentam oferecer adequada estabilidade e maior resistência mecânica, em comparação aos MIs-Ti, quando inseridos em osso de maior densidade. Objetivo TI, , (TI) RF (RF miniimplantes mini implantes MIsAi Ai (MIs-Ai MIsTi. MIsTi Ti . (MIs-Ti) Métodos ( 1 MIsAi, Ai, 12 MIsTi, Ti, lbft3 lbft lb ft3 ft lb/ft (4 PCF. digital (MEV EDS. (EDS) MI avaliados Resultados 11 1, P 0,018. 0018 0,018 0 018 0,018) 54 5 5, p 0,001. 0001 0,001 001 0,001) grupos 98,7 987 98 7 (98, 51 Ncm, 112,0 1120 112 (112, 39 9 3, 120,0 1200 120 (120, 34 Ti. 18 206 06 2,06 391 91 3,91 mecânicos Conclusões vitro mecânica (TI (MIs-Ti (EDS 0,01 01 000 0,00 00 98, (98 112, (112 120, (120 2,0 0,0 (9 (11 (12 0, (1

Abstract Free-living amoebas are natural predators of fungi, including human pathogens of the Cryptococcus genus. To survive and proliferate inside phagocytes, cryptococcal cells must acquire several nutrients. Zinc is fundamental for all life forms and develops a crucial role in the virulence of fungal pathogens, phagocytes reduce the availability of this metal to reduce the development of infection. The Acanthamoeba castellanii ACA1_271600 gene codes a metal transporter that is possibly associated with such antifungal strategy. Here, we evaluated the impact of A. castellanii metal homeostasis on C. gattii survival. Gene silencing of ACA1_271600 was performed and the interaction outcome of amoeba cells with both WT and zinc homeostasis-impaired mutant cryptococcal cells was evaluated. Decreased levels of ACA1_271600 in silenced amoeba cells led to higher proliferation of such cryptococcal strains. This effect was more pronounced in the zip1 mutant of C. gattii, suggesting that ACA1_271600 gene product modulates metal availability in Cryptococcus-infected amoebae. In addition, a systems biology analysis allowed us to infer that ACA1_271600 may also be involved in other biological processes that could compromise amoebae activity over cryptococcal cells. These results support the hypothesis that A. castellanii can apply nutritional immunity to hamper cryptococcal survival. Freeliving Free living fungi genus nutrients infection ACA1271600 ACA ACA1 271600 ACA1_27160 strategy Here A C survival homeostasisimpaired impaired strains zip Cryptococcusinfected infected addition ACA127160 27160 ACA1_2716 ACA12716 2716 ACA1_271 ACA1271 271 ACA1_27 ACA127 27 ACA1_2 ACA12 2 ACA1_

ABSTRACT The significant role of Aedes aegypti as a vector of several arboviruses has intensified studies on vector control tools, including Attractive Toxic Sugar Baits containing Pyriproxyfen (ATSB-PPF). PPF is an insect growth regulator (IGR) that has been used to control immature mosquitoes, but it also has direct effects on female reproduction. This study evaluated the effect of physical exposure of Ae. aegypti females with ATSB-PPF on fecundity and fertility at different times before and after blood meal. Females were confined in cages impregnated with ATSB-PPF at different concentrations (5, 50, and 500 ppm). One group of females was exposed to the baits 24 and 48 hours Before the Blood Meal (BBM), and in the other group, exposure occurred 24 and 48 hours After the Blood Meal (ABM). The number of eggs laid, larvae, and pupation rate were analyzed. Exposure of Ae. aegypti females to ATSB-PPF bait 24 hours after the blood meal was able to reduce the number of eggs laid, especially at the higher concentrations used, but the number of larvae obtained was reduced regardless of the exposure time to ATSB-PPF, i.e., 24 hours before or after the blood meal, or the concentration of PPF used. No changes were observed in the number of pupae from larvae obtained from eggs laid by mosquitoes exposed to ATSB-PPF. Physical exposure of mosquitoes to sugar baits is sufficient to reduce the investigated reproductive parameters of Ae. aegypti. tools ATSBPPF. ATSBPPF ATSB . (ATSB-PPF) IGR (IGR reproduction Ae 5, 5 (5 50 ppm. ppm ppm) 2 4 BBM, BBM , (BBM) ABM. ABM (ABM) analyzed ATSBPPF, PPF, ie i e i.e. PPF. (ATSB-PPF ( (BBM (ABM i.e

Abstract Introduction: Until today, the fishing effort by foreign fleets in the Costa Rican Pacific has not been analyzed. Objective: To determine the spatial distribution of the fishing effort of those fleets, variables that shape that distribution, and if they interact with management figures and highly fragile ecosystems. Methods: Using fishing effort data from 2012 to 2020, obtained from Global Fishing Watch, an Index of Fishing Effort (IEP) was calculated to apply geospatial and multivariate statistics, as well as multiple regression models. A grid with 55 905 cells of 0.10 degrees was used to apply Hot Spot Analysis, and another grid with 24 176 cell-year-month analysis units of 0.25 degrees was used to apply a Linear Regression Model. Results: The data reveals the fishing activity of international fleets associated with four types of fishing gear, and a wide coverage of a high IEP by two fleets throughout the nine years analyzed. The IEP is primarily associated with location and varies by month and year. There is also relative evidence that its influenced by the concentration of oxygen and nitrates. Conclusions: International fleets come into direct conflict with officially defined zones for national fleets and disrespect protected oceanic areas and a declared non-fishing zone to protect marine resources in the Costa Rican Pacific. Their activities in the Dome may affect a national yellowfin tuna fishery.

RESUMEN Objetivo. Determinar la concordancia entre cinco criterios diagnósticos de síndrome metabólico (SM) entre adolescentes residentes de una zona altoandina del Perú. Materiales y métodos. Se realizó un estudio transversal con datos secundarios de un estudio de intervención en dos escuelas públicas en el año 2019. Participaron 397 adolescentes que residen en la ciudad de Cajamarca ubicada en la región andina del Perú. Se aplicaron cinco criterios diagnósticos: Third Adult Treatment Panel (ATP-III) modificados por Cook, de la Federación Internacional de Diabetes (IDF), de la American Heart Association (AHA), de Ferranti, y de la Organización Mundial de Salud (OMS). Se estimaron las prevalencias puntuales y de intervalo con los cinco criterios. Se estimó el coeficiente de concordancia de Kappa con su respectivo intervalo de confianza al 95% (IC 95%). Resultados. El criterio de Ferranti identificó un 17,1% (IC 95%: 13,4 a 20,8) de adolescentes con SM, seguido del criterio de la ATP-III con 4,3% (IC 95%: 2,3 a 6,3); los demás criterios identificaron una menor frecuencia. La mejor concordancia fue encontrada entre los criterios de la AHA y la ATP-III (k = 0,905), los criterios de la OMS e IDF tuvieron un coeficiente de 0,628. Los cinco criterios coincidieron en clasificar como SM a seis adolescentes (1,5%). Conclusiones. Los criterios de la AHA y la ATP-III modificados por Cook tuvieron una concordancia casi perfecta, que se mantuvo en ambos sexos. Los criterios ATP-III, de Ferranti, IDF, AHA y OMS concuerdan en menos del 2% en identificar SM en el mismo grupo de adolescentes.

ABSTRACT Objective. To determine the concordance between five diagnostic criteria for metabolic syndrome (MS) among teenagers from a Peruvian high Andes region. Materials and methods. A cross-sectional study was carried out with secondary data from an intervention study in two public schools in 2019. We included 397 teenagers who lived in the city of Cajamarca, in the Andean region of Peru. We applied the criteria from the Adult Treatment Panel III (ATP-III) modified by Cook, the International Diabetes Federation (IDF), the American Heart Association (AHA), Ferranti, and the World Health Organization (WHO). The point prevalence and interval prevalence were estimated with the five criteria. The Kappa concordance coefficient with an 95% confidence interval (95%CI) was estimated. Results. The Ferranti criterion identified 17.1% (95%CI: 13.4 to 20.8) of teenagers with MS, followed by the ATP-III criterion with 4.3% (95%CI: 2.3 to 6.3); the other criteria identified a lower frequency. The best concordance was found between the AHA and ATP-III criteria (k = 0.905); the WHO and IDF criteria had a coefficient of 0.628. The five criteria coincided in classifying six adolescents (1.5%) as MS. Conclusions. The AHA and ATP-III criteria modified by Cook had almost perfect concordance, which was also found for both sexes. The ATP-III, Ferranti, IDF, AHA and WHO criteria agree in less than 2% when identifying MS in the same group of adolescents.

ABSTRACT Forest dynamics describe the change in structure and composition of forests over time, and is mainly driven by forest growth, a process resulting from size increase and mortality of trees, and recruitment of new individuals. An understanding of forest growth is essential for decision-making and research. An appropriate characterization of growth is only possible through the remeasurement of permanent sample plots over time. Although Chile has a continuous forest inventory system, it has several deficiencies which prevent the effective study of forest growth, mainly because it focuses on stand-level variables and stock estimates but lacks data for individual trees. Furthermore, access to the raw data is limited. In addition, maintaining long-term monitoring of plots to evaluate growth is difficult because of budget restrictions. These combined factors jeopardize the provision of key information regarding native forest dynamics and growth. We propose the establishment of a network of permanent sample plots in the Chilean National System of Protected Areas. Finally, we discuss a monitoring system based on this network by highlighting the advantages in terms of research, dissemination, outreach, and the ease of adding non-woody attributes.

RESUMEN La dinámica de los bosques se refiere al cambio en su estructura y composición en el tiempo, gobernado por su crecimiento, el cual es resultado de los procesos de incremento en tamaño, mortalidad de árboles y reclutamiento de nuevos individuos. Conocer el crecimiento de un bosque es esencial para la toma de decisiones de manejo y en investigación. Una apropiada caracterización del crecimiento de los bosques sólo es posible mediante la remedición de unidades de muestreo permanente en el tiempo. Aunque Chile tiene un sistema de inventario continuo, este posee una serie de deficiencias para el estudio efectivo del crecimiento de bosques; ya que posee un enfoque a nivel de rodal, pero no a nivel individual, y el acceso a los datos crudos es escaso. Por otro lado, los esfuerzos científicos son complejos de mantener en el largo plazo debido a las restricciones presupuestarias. Todo lo anterior configura un escenario adverso para proveer información clave y necesaria respecto al crecimiento de los ecosistemas forestales nativos. En el presente trabajo se propone el establecimiento de una red de unidades de muestreo permanente en bosques del Sistema Nacional de Áreas Silvestres Protegidas del Estado de Chile. Finalmente, se discute un sistema de monitoreo basado en esta red, destacando las ventajas en términos de investigación, difusión y extensión, así como la facilidad que ofrece para agregar atributos no arbóreos.

ABSTRACT Objective. To determine the concordance between five diagnostic criteria for metabolic syndrome (MS) among teenagers from a Peruvian high Andes region. Materials and methods. A cross-sectional study was carried out with secondary data from an intervention study in two public schools in 2019. We included 397 teenagers who lived in the city of Cajamarca, in the Andean region of Peru. We applied the criteria from the Adult Treatment Panel III (ATP-III) modified by Cook, the International Diabetes Federation (IDF), the American Heart Association (AHA), Ferranti, and the World Health Organization (WHO). The point prevalence and interval prevalence were estimated with the five criteria. The Kappa concordance coefficient with an 95% confidence interval (95%CI) was estimated. Results. The Ferranti criterion identified 17.1% (95%CI: 13.4 to 20.8) of teenagers with MS, followed by the ATP-III criterion with 4.3% (95%CI: 2.3 to 6.3); the other criteria identified a lower frequency. The best concordance was found between the AHA and ATP-III criteria (k = 0.905); the WHO and IDF criteria had a coefficient of 0.628. The five criteria coincided in classifying six adolescents (1.5%) as MS. Conclusions. The AHA and ATP-III criteria modified by Cook had almost perfect concordance, which was also found for both sexes. The ATP-III, Ferranti, IDF, AHA and WHO criteria agree in less than 2% when identifying MS in the same group of adolescents.

RESUMEN Objetivo. Determinar la concordancia entre cinco criterios diagnósticos de síndrome metabólico (SM) entre adolescentes residentes de una zona altoandina del Perú. Materiales y métodos. Se realizó un estudio transversal con datos secundarios de un estudio de intervención en dos escuelas públicas en el año 2019. Participaron 397 adolescentes que residen en la ciudad de Cajamarca ubicada en la región andina del Perú. Se aplicaron cinco criterios diagnósticos: Third Adult Treatment Panel (ATP-III) modificados por Cook, de la Federación Internacional de Diabetes (IDF), de la American Heart Association (AHA), de Ferranti, y de la Organización Mundial de Salud (OMS). Se estimaron las prevalencias puntuales y de intervalo con los cinco criterios. Se estimó el coeficiente de concordancia de Kappa con su respectivo intervalo de confianza al 95% (IC 95%). Resultados. El criterio de Ferranti identificó un 17,1% (IC 95%: 13,4 a 20,8) de adolescentes con SM, seguido del criterio de la ATP-III con 4,3% (IC 95%: 2,3 a 6,3); los demás criterios identificaron una menor frecuencia. La mejor concordancia fue encontrada entre los criterios de la AHA y la ATP-III (k = 0,905), los criterios de la OMS e IDF tuvieron un coeficiente de 0,628. Los cinco criterios coincidieron en clasificar como SM a seis adolescentes (1,5%). Conclusiones. Los criterios de la AHA y la ATP-III modificados por Cook tuvieron una concordancia casi perfecta, que se mantuvo en ambos sexos. Los criterios ATP-III, de Ferranti, IDF, AHA y OMS concuerdan en menos del 2% en identificar SM en el mismo grupo de adolescentes.

Abstract Aim: The main objective of this study is to determine the response to the firstline treatment regimen with triple standard therapy (amoxicillin, clarithromycin, omeprazole), to eradicate Helicobacter pylori in a certain population. The goal is to determine if the proposed regimen in international guidelines services is still a suitable option for patients in a certain region of Costa Rica. Methods: The study took place in San Francisco de Asís Hospital, Grecia, Alajuela, Costa Rica. All patients with a Helicobacter pylori infection that were given first- line treatment with triple therapy (amoxicillin, clarithromycin and omeprazole) for its eradication for 14 days, in the period between February of 2017 and February of 2019, were included in the study. Results: A total of 369 cases were identified. The diagnosis was made with biopsy in 96.4% of patients. Response to first-line treatment was achieved in 90.5% corroborated by fecal antigen in 92.1% of all cases. Conclusions: This study shows that triple therapy with amoxicillin, clarithromycin and omeprazole for 14 days maintains an adequate level of efficacy. However, it must be considered that these results are from a specific area and may not reflect the reality of the entire country.

Resumen Objetivo: Este estudio tiene como objetivo principal determinar la respuesta al esquema de tratamiento de primera línea con triple terapia estándar (amoxicilina, claritromicina, omeprazol), para erradicación de Helicobacter pylori en una determinada población, para determinar si este esquema propuesto en guías internacionales es aún una opción adecuada para pacientes en una determinada región de Costa Rica. Métodos: Se realizó una búsqueda en el servicio de gastroenterología del Hospital San Francisco de Asís, Grecia, Alajuela, Costa Rica; de todos los pacientes con infección por Helicobacter pylori y que recibieron tratamiento de primera línea con triple terapia (amoxicilina, claritromicina y omeprazol) por 14 días, en el periodo comprendido entre febrero 2017 a febrero 2019, incluyendo para el análisis solamente en los que se contaba con una prueba confirmatoria posterior a tratamiento, ya fuera por antígeno fecal de H. pylori o biopsia convencional. Resultados: Se identificaron un total de 369 casos. El diagnóstico se realizó con biopsia en el 96,4% de los pacientes. La respuesta al tratamiento de primera línea se alcanzó en un 90.5% corroborada por antígeno fecal en el 92.1% de los casos. Conclusiones: Este estudio muestra que la terapia triple con amoxicilina, claritromicina e Inhibidor de bomba de protones por 14 días mantiene un adecuado nivel de eficacia. Sin embargo, hay que tomar en cuenta que estos datos son únicamente de un área de atracción determinada y puede que no reflejen la realidad de todo el país.

Abstract The present article discusses a philosophical reading of Rulfo’s narrative, specially the story “Luvina”. Making special emphasis in the interpretation of history and antihistoricism, following Nietzsche’s critique. All this with the objective of critically exploring the ideals of the modern figure of progress. Furthermore, the article examines the concept of history, according to Benjamin, taking as its starting point the conception against the hegemonic speeches in occident’s historic narration. We understand this description in terms of catastrophe. Therefore, this analysis functions as a strategy to bring back to memory all the absent victims of the so-called progress. Victims that we find in the forgotten and uprooted characters of the Mexican rural modernity of the mid-20th century, depicted by Rulfo. All these characters portray an anguished subjectivity of post-revolutionary Mexico, who tend to turn towards their own interiority rather than dealing with the absurdity of a world that becomes less human each day.

Resumen El presente artículo propone realizar una lectura filosófica de la narrativa de Rulfo, en especial del cuento “Luvina”, haciendo hincapié en la interpretación de la historia y el antihistoricismo según Nietzsche; con la finalidad de explorar de manera crítica los ideales de la figura moderna del progreso. Igualmente, examina la concepción de la historia -siguiendo a Benjamin- a partir de una noción a contrapelo de los discursos hegemónicos de la narración histórica de Occidente, entendida ésta en clave de catástrofe. Este análisis será comprendido como una estrategia para rememorar a las víctimas ausentes de la figura del progreso histórico, a quienes hallamos en los personajes olvidados y desarraigados de la modernidad rural mexicana de mitad del siglo XX, descrita por Rulfo. Dichos personajes representan una subjetividad angustiada del México posrevolucionario y tienden a volcarse a su interioridad, debido al absurdo de un mundo cada vez más ajeno a lo humano.

Abstract Background: The plant community in southern Texas and the adjacent region in Mexico is Tamaulipan thornscrub (MET). However, the recently published proposals for quantitative hierarchical classification have evidenced the presence of more communities and the need for quantitative descriptions of these associations to determine their conservation status. Question: What is the structure and floristic composition of a semi-thorn shrubland in Reynosa’s northwestern region? Studied species: Tamaulipan low semi-thorn scrubland. Study site and dates: Hills in Reynosa’s northwestern region (Tamaulipas), Mexico. August 2018-July 2019. Methods: Abundance, height and coverage of each plant species were measured on 33 plots of 10 × 10 m. Horizontal structure was analyzed by Importance Value Index, vertical structure was estimated through a modification of the Pretzsch Index and in addition alpha diversity indices were calculated. Results: Richness was 55 species, within 54 genera and 25 families. The importance values were centered mainly in small, spineless shrub species (Lippia graveolens, Calliandra conferta, Turnera diffusa and Krameria ramosissima). The vertical structure presented four defined strata with 50 % of species equally represented in all strata and the remaining 50 % restricted to a single stratum (A = 2.86, Amax = 5.39, Arel = 52.98 %). The species with the highest proportional density were distributed only in stratum IV (0-1.12 m). Conclusions: The community is a clearly defined low semi-thorn scrubland. The structural characteristics indicate that it can be a possible transition plant association between MET and piedmont scrub. This reinforces the proposals of the recently published classification systems.

Resumen Antecedentes: La vegetación del sur de Texas y la región adyacente de México es el matorral espinoso tamaulipeco (MET). Sin embargo, los sistemas de clasificación jerárquicos cuantitativos recientes evidencian la presencia de más comunidades y la necesidad de descripciones cuantitativas para conocer su estado actual. Preguntas: ¿Cómo es la estructura y composición florística de un matorral subinerme en el noreste de México? Especies de estudio: Especies de un matorral bajo subinerme. Sitio y años de estudio: Lomeríos del noreste de México (Reynosa, Tamaulipas). Agosto 2018-julio 2019. Métodos: Se midió la abundancia, altura y cobertura de cada especie en 33 parcelas de 10 × 10 m. La estructura horizontal se analizó mediante el IVI, la vertical mediante una modificación del Índice de Pretzsch, además de calcularse índices de diversidad alfa. Resultados: La riqueza fue de 55 especies, 54 géneros y 25 familias. El valor de importancia se concentró principalmente en los de arbustos pequeños inermes (Lippia graveolens, Calliandra conferta, Turnera diffusa y Krameria ramosissima). La estructura vertical presentó cuatro estratos definidos con 50 % de las especies representadas en todos los estratos y el resto se restringió a un solo estrato (A = 2.86, Amax = 5.39, Arel = 52.98 %). Las especies con mayor densidad proporcional se distribuyeron solo en el estrato IV (0 a 1.12 m). Conclusiones: La comunidad corresponde a un matorral bajo subinerme claramente definido. La estructura indica un posible matorral de transición entre MET y matorral submontano. Esto refuerza las propuestas de clasificación recientemente publicadas.

ABSTRACT Research on olive ridley sea turtle (Lepidochelys olivacea) has emphasized egg-laying females and neonates, using data collected on nesting beaches, but no systematic studies on morphological characteristics by size and sex have been published. This research describes the morphometry of free-living olive ridley sea turtles from coastal and oceanic waters of the Mexican Central Pacific captured and released from 2011 through 2013. A total of 3469 km was surveyed, and 142 sea turtles were evaluated by sex, size class, marine area, and geographic region for nine corporal measurements and their allometric relationships. The average curved carapace length (CCL) was 62.12 cm, range 42-94 cm. Significant differences were found by sex and size class with total tail length (TTL) (♂ = 26.33 cm, ♀ = 12.4 cm); similarly with vent to tail tip length (VTTL) (♂ = 6.38 cm, ♀ = 3.86 cm); and for rear flipper length (RFL) (♂ = 28.17 cm, ♀ = 38.62 cm, immatures = 23.80 cm). Turtles from the coastal region of Colima-Michoacán showed longer CCL = 62.46 cm and wider CW = 66.58 cm. Adult female RFLs showed positive allometry, b = 1.098, suggesting an accelerated growth of the posterior extremities, probably favoring reproductive behaviors, e.g. nest digging and egg-covering. Morphological differences were likely due to ontogenetic sexual distinctions rather than marine area or geographic differences.

Resumen: Introducción: El litio es una molécula farmacológica que se utiliza de forma común en pacientes con trastorno afectivo bipolar. Por su similitud química con el sodio puede generar alteraciones que repercuten directamente en sus concentraciones plasmáticas. Las complicaciones que se pueden presentar son diabetes insípida nefrogénica, disfunción tiroidea y algunos defectos del sistema nervioso central como nistagmos, ataxia, tremor, fasciculaciones, convulsiones y coma. Objetivo: Presentar el caso de una paciente con síndrome de alteración del estado de conciencia secundario a intoxicación por litio. Caso clínico: Mujer de 61 años con antecedente de trastorno afectivo bipolar quien presentó síndrome de alteración del estado de conciencia asociado a una intoxicación por litio, por lo cual se retiró el medicamento y se realizaron sesiones de hemodiálisis, obteniendo una adecuada respuesta con mejoría de la función renal y normalización de los valores séricos de litio (0.76 mmol/L). Conclusiones: El litio puede conllevar alteraciones a nivel renal que se asocian con modificaciones en los electrolitos séricos. Esto puede facilitar la aparición de síntomas o cuadros neurológicos, como se evidenció en el presento caso.

Abstract: Introduction: Lithium is a pharmacological molecule that is commonly used in patients with bipolar affective disorder. Due to its chemical similarity to sodium, alterations in the latter have a direct effect on its plasma concentrations. Among the complications that can occur are nephrogenic diabetes insipidus, thyroid dysfunction, and some central nervous system defects such as nystagmus, ataxia, tremor, fasciculations, seizures, and coma. Objective: To present the case of a patient with a syndrome of altered state of consciousness secondary to lithium poisoning coincide. Clinical case: 61-year-old woman with a history of bipolar affective disorder who presented the syndrome of altered state of consciousness associated with lithium poisoning, for which reason the drug was withdrawn and hemodialysis sessions were carried out, obtaining an adequate response. with improvement of renal function and normalization of serum lithium values (0.76 mmol / L). Conclusions: Lithium may involve alterations at the renal level that are associated with modifications in serum electrolytes. This can facilitate the appearance of neurological symptoms or symptoms, as evidence in the present case.