Abstract Objective: The objective of this study was to investigate the clinical effect of overlap anastomosis and functional end-to-end anastomosis (FEEA) in laparoscopic radical resection of colorectal cancer (CRC). Methods: The clinical data of 180 patients who underwent laparoscopic radical resection of CRC and side-to-side anastomosis were retrospectively collected; the patients were divided into the Overlap group and FEEA group, according to the anastomosis method that was used to treat them. Results: The Overlap group had a shorter operation time, anastomosis time, post-operative hospital stay, post-operative feeding time, and post-operative exhaust time than the FEEA group (p < 0.05). The total incidence of post-operative complications was 14.4% (13/90) in the FEEA group and 0.7% (6/90) in the Overlap group, and there was no significant difference between the two groups (p > 0.05). Conclusions: Overlapping anastomosis can shorten the operation time and accelerate the recovery of intestinal function without increasing the incidence of post-operative complications, and it will not affect the quality of life and survival of patients in the short term after surgery.

Resumen Objetivo: Investigar el efecto clínico de la anastomosis superpuesta y de la anastomosis funcional de extremo a extremo (AFEE) en la resección radical laparoscópica del cáncer colorrectal (CCR). Método: Se recolectaron retrospectivamente los datos clínicos de 180 pacientes sometidos a resección radical laparoscópica de CCR y anastomosis de lado a lado. Los pacientes se dividieron en grupo de anastomosis superpuesta y grupo AFEE, según el método de anastomosis que se utilizó para tratarlos. Resultados: El grupo de anastomosis superpuesta tuvo un tiempo de operación, un tiempo de anastomosis, una estancia hospitalaria posoperatoria, un tiempo de alimentación posoperatorio y un tiempo de escape posoperatorio más cortos que el grupo AFEE (p < 0.05). La incidencia total de complicaciones posoperatorias fue del 14.4% (13/90) en el grupo AFEE y del 0.7% (6/90) en el grupo de anastomosis superpuesta, y no hubo diferencias significativas entre los dos grupos (p > 0.05). Conclusiones: La anastomosis superpuesta puede acortar el tiempo operatorio y acelerar la recuperación de la función intestinal sin aumentar la incidencia de complicaciones posoperatorias, y sin afectar la calidad de vida y la supervivencia de los pacientes a corto plazo después de la cirugía.

RESUMO Objetivo: Explorar os efeitos terapêuticos das lentes de ortoceratologia combinados com colírio atropina 0,01% em miopia juvenil. Métodos: Um total de 340 pacientes com miopia juvenil (340 olhos) tratados entre 2018 e Dezembro de 2020 foram divididos em Grupo Controle (170 casos com 170 olhos, lentes de ortoceratologia) e Grupo Observação (170 casos com 170 olhos, lentes de ortoceratologia combinadas com colírio atropina 0,01%). A acuidade visual melhor corrigida para longe, acuidade visual melhor corrigida para perto, dioptria, comprimento axial, amplitude de acomodação, diâmetro da pupila brilhante, diâmetro da pupila escura, espessura da camada lipídica da película lacrimal e tempo de ruptura do rasgo foram medidos antes do tratamento e 1 ano depois. A incidência de reações adversas foi observada. Resultados: Antes do tratamento, o grau esférico equivalente foi significativamente melhorado em 0,22 (0,06, 0,55) D e 0,40 (0,15, 0,72) D respectivamente no Grupo Observação e no Grupo Controle após o tratamento (p<0,01). Após tratamento, o comprimento axial foi significativamente aumentado em (0,15 ± 0,12) mm e (0,24 ± 0,11) mm respectivamente nos Grupos Observação e controle (p<0,01), enquanto, no grupo de observação, a amplitude de acomodação diminuiu significativamente e foi inferior a do Grupo Controle, e o diâmetro da pupila brilhante e o diâmetro da pupila escura aumentaram significativamente e foram maiores do que os do Grupo Controle (p<0,01). A espessura da camada lipídica da película lacrimal e o tempo de ruptura do rasgo diminuíram significativamente nos dois grupos (p<0,01) após o tratamento. Conclusões: As lentes de ortoceratologia combinadas com colírio atropina 0,01% podem melhorar significativamente o efeito controle em miopia juvenil com elevada segurança. Objetivo 001 0 01 0,01 Métodos 34 (34 olhos 201 202 (17 17 0,01%. . 0,01%) longe perto dioptria depois observada Resultados 022 22 0,2 0,06, 006 06 (0,06 0,55 055 55 040 40 0,4 0,15, 015 15 0,72 072 72 p<0,01. p001 p p<0,01 0,15 (0,1 0,12 012 12 0,24 024 24 (0,2 0,11 011 11 p<0,01, , enquanto observação (p<0,01 Conclusões segurança 00 0,0 3 (3 20 (1 02 2 0, 0,06 (0,0 0,5 05 5 04 4 0,7 07 7 p00 p<0,0 0,1 (0, (p<0,0 ( p0 p<0, (0 (p<0, p<0 (p<0 p< (p< (p

ABSTRACT Purpose: To explore the therapeutic effects of orthokeratology lens combined with 0.01% atropine eye drops on juvenile myopia. Methods: A total of 340 patients with juvenile myopia (340 eyes) treated from 2018 to December 2020 were divided into the control group (170 cases with 170 eyes, orthokeratology lens) and observation group (170 cases with 170 eyes, orthokeratology lens combined with 0.01% atropine eye drops). The best-corrected distance visual acuity, best-corrected near visual acuity, diopter, axial length, amplitude of accommodation, bright pupil diameter, dark pupil diameter, tear-film lipid layer thickness, and tear break-up time were measured before treatment and after 1 year of treatment. The incidence of adverse reactions was observed. Results: Compared with the values before treatment, the spherical equivalent degree was significantly improved by 0.22 (0.06, 0.55) D and 0.40 (0.15, 0.72) D in the observation and control groups after the treatment, respectively (p<0.01). After the treatment, the axial length was significantly increased by (0.15 ± 0.12) mm and (0.24 ± 0.11) mm in the observation and control groups, respectively, (p<0.01). After the treatment, the amplitude of accommodation significantly declined in the observation group and was lower than that in the control group, whereas both bright and dark pupil diameters significantly increase and were larger than those in the control group (p<0.01). After the treatment, the tear-film lipid layer thickness and tear break-up time significantly declined in the two groups (p<0.01). Conclusions: Orthokeratology lens combined with 0.01% atropine eye drops can synergistically enhance the control effect on juvenile myopia with high safety. Purpose 001 0 01 0.01 Methods 34 (34 eyes 201 202 (17 17 drops. . drops) bestcorrected best corrected acuity diopter diameter tearfilm film breakup break up observed Results 022 22 0.2 0.06, 006 06 (0.06 0.55 055 55 040 40 0.4 0.15, 015 15 0.72 072 72 p<0.01. p001 p p<0.01 (p<0.01) 0.15 (0.1 0.12 012 12 0.24 024 24 (0.2 0.11 011 11 Conclusions safety 00 0.0 3 (3 20 (1 02 2 0. 0.06 (0.0 0.5 05 5 04 4 0.7 07 7 p00 p<0.0 (p<0.01 0.1 (0. ( p0 p<0. (p<0.0 (0 p<0 (p<0. p< (p<0 (p< (p

Abstract Despite the record speed of developing vaccines and therapeutics against the SARS-CoV-2 virus, it is not a given that such success can be secured in future pandemics. In addition, COVID-19 vaccination and application of therapeutics remain low in developing countries. Rapid and low cost mass production of antiviral IgY antibodies could be an attractive alternative or complementary option for vaccine and therapeutic development. In this article, we rapidly produced SARS-CoV-2 antigens, immunized hens and purified IgY antibodies in 2 months after the SARS-CoV-2 gene sequence became public. We further demonstrated that the IgY antibodies competitively block RBD binding to ACE2, neutralize authentic SARS-CoV-2 virus and effectively protect hamsters from SARS-CoV-2 challenge by preventing weight loss and lung pathology, representing the first comprehensive study with IgY antibodies. The process of mass production can be easily implemented in most developing countries and hence could become a new vital option in our toolbox for combating viral pandemics. This study could stimulate further studies, optimization and potential applications of IgY antibodies as therapeutics and prophylactics for human and animals.

Resumo: A filosofia contribui significativamente para a herança do pensamento humano e do espírito humanista. As explorações tradicionais da filosofia, geralmente racionais e abstratas, podem ter dificuldade em se envolver profundamente com as emoções e experiências humanas. Este artigo investiga a expressão de ideias filosóficas, por meio da música vocal, especialmente durante a era romântica, para preencher essa lacuna. Ao examinar a integração de conceitos filosóficos, nas composições vocais do século XIX, o estudo destaca como a música vocal pode servir como um meio potente para o discurso filosófico. O estudo explora a relação simbiótica entre a música vocal e a filosofia, analisando como as árias expressam e perseguem questionamentos filosóficos. Esta pesquisa avalia o papel da música vocal na exploração filosófica, através de três dimensões: expressão emocional, comunicação conceitual e impacto inspirador. As descobertas visam a demonstrar o poder transformador da música, para transmitir pensamentos filosóficos, inspirando uma contemplação mais profunda da vida, da existência e dos valores, além de incentivar uma reavaliação da capacidade única da música vocal de comunicar ideias profundas. Resumo humanista abstratas humanas filosóficas romântica lacuna filosóficos XIX filosófico filosófica dimensões emocional inspirador vida valores profundas

Abstract: Philosophy significantly contributes to the inheritance of human thought and the humanistic spirit. Traditional explorations in philosophy, often rational and abstract, may struggle to engage deeply with human emotions and experiences. This article delves into the expression of philosophical ideas through vocal music, particularly during the Romantic era, to bridge this gap. By examining the integration of philosophical concepts into 19th-century vocal compositions, the study highlights how vocal music can serve as a potent medium for philosophical discourse. It explores the symbiotic relationship between vocal music and philosophy, analyzing how arias express and pursue philosophical inquiries. This research evaluates the role of vocal music in philosophical exploration through three dimensions: emotional expression, conceptual communication and inspirational impact. The findings aim to demonstrate the transformative power of music to convey philosophical thoughts, inspiring deeper contemplation of life, existence and values, and encouraging a reevaluation of the unique capacity of vocal music to communicate profound ideas. Abstract spirit philosophy abstract experiences era gap 19thcentury thcentury 19th century th compositions discourse inquiries dimensions impact thoughts life values

Abstract Objective Dizziness or vertigo in older population frequently presents in clinical settings, yet its etiology remains elusive. The objective of this study was to delineate global trends and identify frontiers in research concerning dizziness or vertigo among older population. Methods We searched the research literature published from 2003 to 2022 on older population with dizziness or vertigo using two databases from the Web of Science Core Collection. A bibliometric and visualization analysis was conducted. Bibliometric tools facilitated co-authorship, co-citation, and keyword co-occurrence analyses, encompassing countries or regions, institutions, authors, journals, and references. Results The analysis included 1322 publications authored by 6524 individuals from 2244 institutions across 67 countries or regions, spanning 92 subject categories. A steady increase in publications was noted from 2003 to 2022. The University of Munich, Harvard University, and the University of California System emerged as leading institutions with the highest publication outputs. The United States, Germany, and China were predominant in publication counts. Eva Grill was identified as the most prolific author. Otology & Neurotology and Geriatrics & Gerontology emerged as the most prolific journal and subject category, respectively. The most prevalent keywords were “dizziness”, “vertigo”, “falls”, and “geriatric”, with “management”, “gait”, and “association” recognized as the principal research hotspots. Conclusion This study provides a systematic analysis of global scientific research on older population dizziness/vertigo, revealing significant advancements in understanding over the past two decades. Management, gait, and association have emerged as the primary research focuses on recent years. These findings offer valuable insights for directing current research efforts to capture prevailing trends and explore new frontiers in this field. settings elusive 200 202 Collection conducted coauthorship, coauthorship co authorship, authorship co-authorship cocitation, cocitation citation, citation co-citation cooccurrence occurrence analyses regions authors journals references 132 652 224 6 9 categories Munich outputs States Germany counts author category respectively dizziness, , “dizziness” vertigo, “vertigo” falls, falls “falls” geriatric, geriatric “geriatric” management, management “management” gait “gait” “association hotspots dizzinessvertigo dizziness/vertigo decades Management years field 20 13 65 22 “dizziness “vertigo “falls “geriatric “management “gait 2 1

Abstract With the outbreak of the COVID-19 pandemic, artificial intelligence (AI) has been widely used in fields such as medical treatment, while the threat of artificial intelligence has also received extensive attention. However, this topic has been only limitedly explored in China. To provide a measurement tool for AI threat research in China, this study aimed to examine the validity and reliability of the Threats of Artificial Intelligence Scale (TAI) in two Chinese samples of adults (N1 = 654, N2 = 1483). Results of exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) suggested that the one-factor model of TAI as the best fitting model. Furthermore, the Chinese TAI was significantly related to Positive and Negative Affect Scale and Self-Rating Anxiety Scale, proving good criterion-related validity of the Chinese TAI. In sum, this study suggested the Chinese version of the TAI as a reliable and effective tool in assessing AI threat in the Chinese context. Limitations and future directions are discussed. COVID19 COVID 19 COVID-1 pandemic (AI treatment attention However China (TAI N1 N (N 654 1483. 1483 . 1483) EFA (EFA CFA (CFA onefactor one Furthermore SelfRating Self Rating criterionrelated criterion sum context discussed COVID1 1 COVID- 65 148 6 14

ABSTRACT The application of intelligent materials in drilling fluids has greatly reduced the investment of human resources and effectively made up for the shortcomings of traditional drilling fluids, such as insufficient directivity, poor adaptive ability and difficult monitoring. Therefore, the research of intelligent drilling fluids is a valuable direction for the future oil and gas industry. In this study, the temperature-sensitive modified bentonite NIPAM-B developed by Pan Yi et al. was used as the drilling fluid base slurry, and the drilling fluid additives were optimized to complete the modulation of the intelligent drilling fluid inspection system. In addition, the rheology, filtration, shale wellbore stability and stability of the intelligent drilling fluid inspection system will be evaluated. The results show that the intelligent drilling fluid has good temperature-sensitive thickening performance, and the rheology is not affected by temperature changes, which can realize intelligent heating and thickening. In addition, compared with the original bentonite drilling fluid system, the intelligent drilling fluid has good fluid loss reduction ability and shale borehole wall protection ability, and the shale rolling recovery rate reaches more than 95 %. directivity monitoring Therefore industry study temperaturesensitive sensitive NIPAMB NIPAM B al slurry addition filtration evaluated performance changes 9 %

Aerospace and military defense fields are posing higher requirement on the lightweight feature of structures. Subject of this study is the Aluminum Alloy 5A02 /CFRTP (Carbon Fiber Reinforced Thermo-Plastic) laminates. In the paper, aluminum alloy was anodized, compression molding and 3D printing were adopted to prepare Carbon Reinforced Aluminum Laminates (CARALL) with two different structures: the solid core structure and the honeycomb structure, and the prepared specimens were then tested for mechanical properties via tensile test and three-point bending test, and compared with the performance of the conventional aluminum alloy. The results show that under the condition of a same thickness, the tensile strength of CARALL specimens with the molded solid core structure and the 3D printed honeycomb structure reaches 256Mpa and 186MPa, respectively, which is 85.5% and 34.8% higher than that of the tensile strength of Al 5A02; under different bending modes, the maximum bending strength is 682Mpa and 525Mpa, respectively, which is 62.4% and 25.5% higher than that of Al 5A02. When the specimens are subject to tensile force, the separation of the metal layer and the fiber layer is the primary failure form, the fiber layer fractures, and the metal layer exhibits the necking phenomenon as the metal fibers are being pulled out. During the bending process, for different bending forms, there’re great differences in the bending strength of CARALL specimens prepared by the same method, the failure modes of the specimens vary greatly as well, and this is determined by the tensile strength of the carbon fiber layer and the tensile strength of AL 5A02. Enhancing the bonding strength between the metal layer and the fiber layer can improve the mechanical properties of CARALL. These research findings can provide a reference for the lightweight design of metals and Fiber Metal Laminates (FMLs). structures A 5A0 CFRTP ThermoPlastic Thermo Plastic Thermo-Plastic laminates paper anodized D (CARALL threepoint three point thickness Mpa 186MPa MPa respectively 855 85 5 85.5 348 34 8 34.8 525Mpa 624 62 4 62.4 255 25 25.5 force form fractures out process forms therere there re method well FMLs. FMLs . (FMLs) 5A 85. 3 34. 6 62. 2 25. (FMLs

Resumo Introdução A abordagem padrão para tireoidectomia é uma incisão em colar na face anterior do pescoço; a cicatriz no pescoço sempre foi uma fonte de preocupação para os pacientes; consequentemente, a cosmetologia aceitável da ferida tornou‐se um foco de atenção para os cirurgiões de cabeça e pescoço. Objetivos Verificar a eficácia e os resultados cosméticos da tireoidectomia por meio de incisão supraclavicular lateral. Método Foram divididos aleatoriamente 180 pacientes em dois grupos: um grupo supraclavicular lateral (Grupo LS) e outro transcervical convencional (Grupo TC). Os desfechos principais incluíram comprimento da incisão, perda de sangue intraoperatória, tempo cirúrgico, volume total de drenagem, despesas hospitalares, dor no pós‐operatório imediato medida através de escala visual analógica, infecção e resultado cosmético percebido. Resultados Não houve significância estatística entre os dois grupos em termos de idade, sexo, tamanho do nódulo, perda sanguínea intraoperatória, tempo cirúrgico, volume total de drenagem, custo hospitalar e complicações pós‐operatórias, mas houve diferença significante em termos de comprimento da incisão (5,2 ± 1,04 cm vs. 6,9 ± 1,14 cm, p < 0,05). Conclusão A incisão supraclavicular lateral é uma abordagem segura e viável para tireoidectomia. Em comparação com a abordagem convencional, oferece um melhor resultado cosmético. consequentemente tornouse tornou se 18 Grupo LS TC. TC . TC) intraoperatória cirúrgico drenagem hospitalares pósoperatório pós operatório analógica percebido idade sexo nódulo pósoperatórias operatórias pós‐operatórias 5,2 52 5 2 (5, 104 1 04 1,0 vs 69 6 9 6, 114 14 1,1 0,05. 005 0,05 0 05 0,05) 5, (5 10 1, 11 00 0,0 ( 0,

Abstract Introduction The standard approach to thyroidectomy is a collar incision via the anterior neck, and the neck scar has always been a source of worry for patients. Acceptable wound cosmetology has become a focus for thyroid surgeons. Objective To verify the effectiveness and cosmetic results of thyroidectomy through a lateral supraclavicular incision. Methods 180 patients were randomly divided into two groups: a lateral supraclavicular approach and a conventional transcervical approach. The main outcomes included incision length, intraoperative blood loss, operative time, total drainage volume, hospitalization expense, early postoperative pain measured by visual analog scale, infection, and perceived cosmetic outcome. Results There were no statistical significances between the two groups in terms of age, gender, nodule size, intraoperative blood loss, operative time, total drainage volume, hospital expense and postoperative complications, whereas there were significant differences in terms of incision length (5.2 ± 1.04 cm vs. 6.9 ± 1.14 cm, p < 0.05). Conclusions The lateral supraclavicular incision is a safe and feasible approach for thyroidectomy. Compared with conventional approach, it provides a better cosmetic result. surgeons 18 loss time volume scale infection outcome age gender size complications 5.2 52 5 2 (5. 104 1 04 1.0 vs 69 6 9 6. 114 14 1.1 0.05. 005 0.05 . 0 05 0.05) result 5. (5 10 1. 11 00 0.0 ( 0.

Abstract In this study, Illumina MiSeq was used to investigate the microbial diversity ofwine grapes and soil from three vineyards indifferent localities on the eastern foothills of Helan Mountain in Ningxia, China. The results of 26 samples showed thatthere were 4 fungal phyla with 1107 operational taxonomic units (OTUs) and 11 bacterial phyla with 4630 OTUs. At the genus level, the dominant fungi in the grapes included Aspergillus, Alternaria, Exobasidum, Aureobasidium, and Cladosporium, while the dominant fungi in the soil included Gibberella, Gliomastix, Coprinellus, Fusarium, and Chaetomium, Chryseobacterium, Mesorhizobium, Pseudomonas, Microbacterium and Acinetobacter were the dominant bacteria in the grapes, while Arthrobacter, Pontibacter, Massilia, Skermanella, and Candiatus-Nitrosocosmicus were the dominant bacteria in the soil. Principal component analysis showed that the microbial diversity differed in the three vineyards from different geographical locations. This study provides a theoretical basis for the utilization and development of the characteristic microorganisms in vineyards.

Abstract Based on the Essential Science Indicators database, this study analyzed 2,886 top papers in the subject category of Food Science and Technology from January 2011 to June 2021. The 2,886 top papers include 2,882 highly cited papers and 56 hot papers. All papers written in English, were from 10,698 authors, 2,666 organizations and 115 countries/territories, published in 106 journals and two book series in the field. The top five Journals are Food Chemistry, Food Hydrocolloids, Trends in Food Science Technology, Critical Reviews in Food Science and Nutrition and Journal of Agricultural and Food Chemistry. The top six countries and regions were Peoples R China, USA, Spain, Italy, Brazil and India. The top six organizations of Jiangnan University, University of Massachusetts, South China University of Technology, Zhejiang University, Jiangsu University and University of Valencia were popular based on contribution of articles more than 45 papers each. The top five authors were Mcclements David Julian, Sun Da-Wen, Barba Francisco J., Lorenzo Jose M. and Zhang Min. All keywords were separated seven clusters for different research topic. Visualizations offer exploratory information on the current state in a scientific field or discipline as well as indicate possible developments in the future.

Abstract This study aimed to identify and analyze the 3,872 article and review type papers of blueberry research based on Web of Science. Papers mainly written in English (3,769, 97.34%), were from 10,102 authors, 83 countries or territories, 2,033 organizations and published in 770 Journals and three book series. The top five Journals were HortScience (278, 7.18%), Journal of the American Society for Horticultural Science (272, 7.024%), Journal of Agricultural and Food Chemistry (116, 2.996%), Journal of Economic Entomology (97, 2.505%), Food Chemistry (92, 2.376%). The top five countries and regions were USA, Peoples R China, Canada, Chile and Brazil. The six most paper contributed organizations were USDA ARS, University of Florida, Michigan State University, University of Georgia, Agriculture and Agri-Food Canada, and University of Maine. The top five authors were Hancock, James F.; Rowland, Lisa J.; Ehlenfeldt, Mark K.; Lyrene, Paul M.; and Strik, Bernadine C. All keywords of the blueberry research based on Web of Science were separated into seven clusters for different research topics. This review could provide a valuable guide for designing future studies. This work is also useful for student identifying graduate schools and researchers selecting journals.

Abstract Trust in automation plays a leading role in human-automation interaction. As there lack of scales measuring trust in automation in China, the purpose of this study was to adapt the trust between People and Automation Scale (TPAS) into Chinese and to demonstrate its psychometric properties among Chinese adults. A total of 310 Chinese adults were randomly selected as sample 1, and 508 Chinese adults as sample 2. Results of the item analysis revealed that each item had a good quality, and the exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) suggested that the two-factor model with 12 items was the best fitting model. In addition, the TPAS was positively correlated with Interpersonal Trust Scale (ITS), proving good evidence based on relations to other variables to support the TPAS. In sum, the study suggested that the Chinese version of the TPAS could be used as an effective tool to assess trust in automation in the Chinese context.

Abstract Black tea has a long history in China, but in export trade, pesticide residues often exceed the standard. To obtain a rapid, accurate, and non-destructive identification method of pesticide residues on black tea, the fluorescence hyperspectral data of dry black tea sprayed with distilled water and six pesticides were collected in this study. The spectra were preprocessed by multiplicative scatter correction (MSC) and standard normal variate (SNV). Then the uninformative variable elimination (UVE), successive projections algorithm (SPA), competitive adaptive re-weighted sampling (CARS), UVE-SPA, and CARS-SPA were used to feature extraction. This study proposes a machine learning model composed of a one-dimensional convolutional neural network backbone (1D CNN backbone) and a random forest classifier (RF classifier) to identify pesticide residues on black tea, and the 1D CNN-RF model was compared with three other machine learning models (support vector machine, RF, and 1D CNN). The results show that MSC-CARS-SPA-1D CNN-RF is the best model for identifying pesticide residues on black tea in which the accuracy of the test set is 99.05%. Combined with fluorescence hyperspectral technology, the proposed 1D CNN-RF model has great potential in the non-destructive identification of pesticide residues on black tea.