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Ultra-Low-Dose Computed Tomography for Pneumonia in the Emergency Department: A Feasibility Study
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Bianco, Danilo P.
; Accorsi, Tarso A. D.
; Souza, Jose L.
; Mello, Eduardo S.
; Silva, Joselito A.
; Teles, Gustavo B. S.
; Chate, Rodrigo C.
; Santos, Andre R. C.
; Moron, Renato A.
; Mattos, Fernando R.
; Teles, Adriana Gusman
; Oliveira, Roger Pereira
; Almeida, Elizabeth Aparecida
; Zimmer, Paulo M.
; Funari, Marcelo B. G.
; Benveniste, Marcelo
; Szarf, Gilberto
.
Resumo Introdução: O papel da tomografia computorizada torácica de ultrabaixa dose (ULDCT) em contexto de urgência é desconhecido. Objetivo: Este estudo avaliou a viabilidade da ULDCT em adultos na urgência com suspeita de pneumonia. Foram medidos a dose de radiação, o tempo entre a solicitação e os relatórios do exame, prescrições de antimicrobianos também foram correlacionadas. Métodos: Este estudo avaliou a viabilidade da ULDCT em adultos na urgência com suspeita de pneumonia. Foram medidas a dose de radiação, o tempo entre a solicitação e a disponibilização dos relatórios do exame, e também foram correlacionadas as prescrições de antimicrobianos. Entre outubro de 2017 e dezembro de 2018, incluímos prospectivamente adultos com suspeita de pneumonia adquirida na comunidade, sem diagnóstico definitivo por avaliação clínica. Os critérios de exclusão abrangeram condições clínicas que pudessem afetar a interpretação da imagem. Resultados: Foram incluídos 131 pacientes elegíveis (idade média de 43,5 anos; 57% homens) encaminhados para ULDCT. Dezoito (13,7%) foram excluídos. A dose média de radiação da ULDCT foi de 0,14 mSv. O intervalo de tempo entre a solicitação médica e o resultado da ULDCT foi de 43 minutos. Conclusão: A ULDCT mostrou-se viável para pacientes adultos com suspeita de pneumonia em contexto de urgência. Os relatórios foram disponibilizados num intervalo razoável e os resultados negativos foram associados a uma baixa taxa de prescrição de antibióticos.
Abstract Background: The role of ultra-low-dose chest CT (ULDCT) in the emergency department is unknown. Purpose: This study sought to examine feasibility of ULDCT in adults presenting to the emergency department for whom pneumonia was suspected. Radiation dose and time interval between medical request and ULDCT results were measured, antibiotic prescriptions were correlated. Methods: Between October 2017 and December 2018, we prospectively enrolled consecutive healthy adult patients in a single-center for whom community-acquired pneumonia was suspected and for whom no definitive diagnosis was possible by clinical judgment. Exclusion criteria comprised all chronic conditions that could impact severity and interpretation of image. Results: 131 eligible patients (mean age 43.5 years; 57% men) were enrolled to ULDCT. Eighteen (13.7%) patients were excluded. Average CT radiation dose was 0.14 mSv. Time interval between medical request and ultra-low-dose chest CT result was 43 minutes. Only 15.9% of patients with negative CT received antibiotics. Conclusion: Ultra-low-dose chest CT was feasible for almost all patients in a group of healthy adults presenting to the emergency department with suspected community-acquired pneumonia. Results were made available in a reasonable interval, and negative ones were associated with a low antibiotic prescription rate.
2.
Advances in Breast Cancer Drug Discovery: A Review of Therapeutic Strategies and Studies Involving Photosensitizers, Caged Xanthones and Thiosemicarbazones Derivatives Discovery Photosensitizers
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Oliveira, Douglas D. S.
; Lapierre, Thibault J. W. Jacques Dit
; Silva, Fernanda C.
; Cunha, Ieda V.
; Souza, Rafael A. C.
; Matos, Patrícia A.
; Almeida, Gustavo M.
; Oliveira, Carolina G.
; Araújo, Thaise G.
; Tsubone, Tayana M.
; Rezende Jr., Celso O.
.
Journal of the Brazilian Chemical Society
- Métricas do periódico
Cancer is one of the major causes of death worldwide, and breast cancer is the most prevalent and deadly type among women. Despite the side effects and the phenomena of chemoresistance associated with the drugs involved, chemotherapy remains the main therapeutic strategy to combat and control breast cancer. Therefore, several new classes of compounds against breast cancer have been explored, in an effort to identify new drug candidates with alternative mechanisms of action. The principal results of such exploration, focusing on caged xanthones, thiosemicarbazones and photosensitizers, are presented in this review, along with the main aspects of the drug discovery process against breast cancer. More specifically, the design, structure-activity relationship investigations and anti-breast cancer properties of these three classes are described and discussed in this work. worldwide women involved Therefore explored action exploration xanthones photosensitizers review specifically design structureactivity structure activity antibreast anti work
3.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
4.
Coleoptera of Brazil: what we knew then and what we know now. Insights from the Catálogo Taxonômico da Fauna do Brasil Brazil now
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Caron, Edilson
; Monné, Marcela L.
; Ferreira, Vinicius S.
; Costa, Cleide
; Cupello, Mario
; Aloquio, Sergio
; Linzmeier, Adelita M.
; Vaz-de-Mello, Fernando Z.
; Leivas, Fernando W.T.
; Souza-Gonçalves, Igor
; Mermudes, José R.M.
; Almeida, Lúcia M.
; Moura, Luciano de A.
; Ferreira Júnior, Nelson
; Grossi, Paschoal C.
; Vanin, Sergio A.
; Ślipiński, Adam
; Anichtchenko, Alexander
; Newton, Alfred F.
; Sampaio, Aline
; Carelli, Allan
; Puker, Anderson
; Ferreira, André da S.
; Fernandes, André S.
; Roza, André S.
; Cline, Andrew
; Sampaio, Brunno H.L.
; Clarkson, Bruno
; Castro, Camila F. de
; Bicho, Carla de L.
; Benetti, César J.
; Ribeiro-Costa, Cibele S.
; Lopes-Andrade, Cristiano
; Manfio, Daiara
; Colpani, Daniara
; Basílio, Daniel S.
; Bená, Daniela de C.
; Pollock, Darren A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Chandler, Donald S.
; Nascimento, Elynton A. do
; Spiessberger, Erich L.
; Agrain, Federico A.
; Barbosa, Felipe F.
; Shockley, Floyd
; Nascimento, Francisco E. de L.
; Biffi, Gabriel
; Powell, Gareth S.
; Morse, Geoffrey E.
; Flores, Gustavo E.
; Escalona, Hermes
; Quintino, Hingrid Y.S.
; Rainho, Hugo L.
; Maddalena, Italo S.C.P.
; Hájek, Jiří
; McHugh, Joseph V.
; Botero, Juan P.
; Fuhrmann, Juares
; Churata-Salcedo, Julissa M.
; Vieira, Letícia M.
; Silveira, Luiz F.L. da
; Cruz, Luiza S. da
; Sekerka, Lukás
; Bologna, Marco A.
; Bevilaqua, Marcus V.O.
; Passos, Maria I.
; Chamorro, Maria L.
; Cherman, Mariana A.
; Bento, Matheus
; Gimmel, Matthew
; Segura, Melissa O.
; Ivie, Michael A.
; Thomas, Michael C.
; Monné, Miguel A.
; Lord, Nathan
; Hamada, Neusa
; Degallier, Nicolas
; Santos, Paula B. dos
; Duarte, Paulo R.M.
; Gnaspini, Pedro
; Bulirsch, Petr
; Regalin, Renato
; Leschen, Richard A.B.
; Constantin, Robert
; Corrêa, Rodrigo C.
; Gerstmeier, Roland
; Rosa, Simone P.
; Campos, Stéphanie V.N.
; Peck, Stewart B.
; Pacheco, Thaynara L.
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Grzymala, Traci L.
; Smith, Trevor R.
; Costa-Silva, Vinicius da
; Sandoval-Gómez, Vivian E.
; Sousa, Wesley O. de
; Tomaszewska, Wioletta
.
ABSTRACT In 2000, Cleide Costa published a paper presenting the state of knowledge of the Neotropical Coleopte ra, with a focus on the Brazilian fauna. Twenty-four years later, thanks to the development of the Coleoptera section of the Taxonomic Catalog of the Brazilian Fauna (CTFB - Catálogo Taxonômico da Fauna do Brasil) through the collaboration of 100 coleopterists from all over the globe, we can build on Costa’s work and present an updated overview of the state of knowledge of the beetles from Brazil. There are currently 35,699 species in 4,958 genera and 116 families known to occur in the country, including representatives of all extant suborders and superfamilies. Our data show that the Brazilian beetle fauna is the richest on the planet, concentrating 9% of the world species diversity, with some estimates accounting to up to 15% of the global total. The most diverse family in numbers of genera is Cerambycidae (1,056 genera), while in number of species it is Chrysomelidae (6,079 species). Conotrachelus Dejean, 1835 (Curculionidae) is the most species-rich genus, with 570 species. The French entomologist Maurice Pic is the author who has contributed the most to the naming of species recorded from Brazil, with 1,794 valid names in 36 families, whereas the Brazilians Ubirajara R. Martins and Maria Helena M. Galileo are the only ones among the top-ten authors to have named species in the 21st century. Currently, approximately 144 new species of Brazilian beetles are described each year, and this average is projected to increase in the next decade to 180 species per year, or about one new Brazilian beetle every two days. 2000 ra Twentyfour Twenty four later CTFB Brasil 10 globe Costas s Brazil 35699 35 699 35,69 4958 4 958 4,95 11 country superfamilies planet 9 diversity 15 total 1,056 1056 1 056 (1,05 genera, , genera) 6,079 6079 6 079 (6,07 . species) Dejean 183 Curculionidae (Curculionidae speciesrich rich genus 57 1794 794 1,79 3 R M topten top ten st century Currently 14 year 18 days 200 3569 69 35,6 495 95 4,9 1,05 105 05 (1,0 6,07 607 07 (6,0 5 179 79 1,7 20 356 35, 49 4, 1,0 0 (1, 6,0 60 (6, 17 7 1, 2 (1 6, (6 (
5.
Agronomic characterization of acerola tree genotypes in the Gurgueia Valley region, Piauí, Brazil region Piauí
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Monte Junior, Francisco Almir Campelo
; Evangelista, Thamyres Yara Lima
; Aguiar, Cibele Divino
; Cavalcante, Emanuela Sousa
; Cunha, Jenilton Gomes da
; Pereira, Gustavo Alves
; Souza, Flávio de França
; Silva Júnior, Gabriel Barbosa da
.
RESUMO: A seleção de plantas conduzida em pomares comerciais é baseada principalmente nas características da planta. Este trabalho teve como objetivo caracterizar e selecionar genótipos de aceroleira com características promissoras para cultivo na região do Vale do Gurguéia, Piauí. Foram utilizados 25 genótipos, sendo 15 clones (CL 03, CL 08, CL 09, CL 12, CL 13, CL 14, CL 20, CL 23, CL 26, CL 27, CL 30, CL 31, CL 33, CL 36 e CL 38) e 10 cultivares (BRS 235, BRS 236, BRS 237, BRS 238, BRS 366, Sertaneja, Costa Rita, Morena, Tropicana e Junko). O experimento foi instalado no delineamento de blocos casualizados com três blocos e três plantas por unidade experimental no espaçamento de 4 m x 3 m. Um total de 40% dos genótipos avaliados apresentou formato guarda-chuva, 36% formato semiaberto e 24% formato aberto. Os clones 09, 14 e 12 apresentaram o maior potencial de cultivo da região, com produção mensal de 5,01, 4,30 e 3,70 kg planta-¹ por ano e produtividade de 4,16, 3,59 e 3,08 ton ha-¹, respectivamente. O clone 27, as cultivares BRS 236 e BRS 235 e o clone 14 foram os genótipos mais precoces, requerendo 1.503,3, 1.535,6, 1.686,6 e 1.686,6 DD, respectivamente, para completar seu ciclo. Os clones 09 e 14 se destacaram em relação aos demais e são potencialmente promissores para cultivo na região do Vale do Gurgueia. RESUMO planta Gurguéia Piauí 2 1 03 08 13 20 23 26 27 30 31 33 38 237 238 366 Sertaneja Rita Morena Junko. Junko . Junko) 40 guardachuva, guardachuva guarda chuva, chuva guarda-chuva 24 aberto 501 5 01 5,01 430 4,3 370 70 3,7 planta¹ ¹ planta- 416 16 4,16 359 59 3,5 308 3,0 ha¹, ha¹ ha ¹, ha-¹ respectivamente precoces 15033 503 1.503,3 15356 535 6 1.535,6 16866 686 1.686, DD ciclo 0 Gurgueia 50 5,0 43 4, 37 7 3, 41 4,1 35 ha- 1503 1.503, 1535 53 1.535, 1686 68 1.686 5, 150 1.503 153 1.535 168 1.68 1.50 1.53 1.6 1.5 1.
ABSTRACT: Plant selection conducted in commercial orchards is mainly based on plant features. This study characterizes and selects acerola tree genotypes with promising features for cultivation in the Gurguéia Valley region, Piauí. Twenty-five genotypes were used, consisting of 15 clones (CL 03, CL 08, CL 09, CL 12, CL 13, CL 14, CL 20, CL 23, CL 26, CL 27, CL 30, CL 31, CL 33, CL 36, and CL 38) and 10 cultivars (BRS 235, BRS 236, BRS 237, BRS 238, BRS 366, Sertaneja, Costa Rita, Morena, Tropicana, and Junko). The experiment was set up in a randomized block design with three blocks and three plants per experimental unit in 4 m x 3 m spacing. A total of 40% of the genotypes evaluated showed an umbrella shape, 36% showed a semi-open shape, and 24% showed an open shape. Clones 09, 14, and 12 presented the highest cultivation potential in the region, with monthly production of 5.01, 4.30, and 3.70 kg plant-¹ per year and productivity of 4.16, 3.59, and 3. 08-ton ha-¹, respectively. Clone 27, cultivars BRS 236 and BRS 235, and clone 14 were the earliest genotypes, requiring 1,503.3, 1,535.6, 1,686.6, and 1,686.6 DD; respectively, to complete their cycle. Clones 09 and 14 stood out from the others and are potentially promising for cultivation in the Gurgueia Valley region. ABSTRACT region Piauí Twentyfive Twenty five used 1 03 08 13 20 23 26 27 30 31 33 36 38 235 237 238 366 Sertaneja Rita Morena Tropicana Junko. Junko . Junko) spacing 40 shape semiopen semi 24 501 5 01 5.01 430 4.30 370 70 3.7 plant¹ ¹ plant- 416 16 4.16 359 59 3.59 08ton ton ha¹, ha¹ ha ¹, ha-¹ respectively 15033 503 1,503.3 15356 535 6 1,535.6 16866 686 1,686. DD cycle 0 2 50 5.0 43 4.3 37 7 41 4.1 35 3.5 ha- 1503 1,503. 1535 53 1,535. 1686 68 1,686 5. 4. 150 1,503 153 1,535 168 1,68 1,50 1,53 1,6 1,5 1,
6.
Descobrindo os sujeitos do mercado: “Quem somos nós quando trabalhamos?” mercado Quem trabalhamos trabalhamos?
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Resumen El artículo de Lisa Herzog examina cómo Adam Smith y G. W. F. Hegel conceptualizan la identidad de los trabajadores en una economía de mercado. Aunque ambos ven a los seres humanos moldeados en y a través de relaciones sociales, la relación entre el trabajador y su trabajo es vista por ellos de manera diversa. Para Smith, los trabajadores “tienen” capital humano, mientras que para Hegel los trabajadores “son” cerveceros, carniceros o panaderos; su profesión es parte de su identidad. Esta diferencia conceptual, que se refleja en diferentes “variedades de capitalismo” hoy, muestra que al debatir las relaciones entre el individuo y la sociedad se deben distinguir no sólo los grados, sino también los tipos de arraigo. El artículo es antecedido de una introducción escrita por los traductores. G W F mercado sociales diversa tienen “tienen humano son “son cerveceros panaderos conceptual variedades capitalismo hoy grados arraigo traductores
Abstract Lisa Herzog’s article examines how Adam Smith and G. W. F. Hegel conceptualize the identity of workers in a market economy. Although both see human beings as shaped in and through social relationships, the relation between the worker and his or her work is seen by them differently. For Smith, workers “have” human capital, while for Hegel workers “are” brewers, butchers or bakers; their profession is part of their identity. This conceptual difference, which is reflected in different “varieties of capitalism” today, shows that not only degrees, but also kinds of embeddedness should be distinguished when debating the relationships between individual and society. Before the article there is an Introduction by the translators. Herzogs Herzog s G W F economy differently have “have capital are “are brewers bakers difference varieties capitalism today degrees society translators
Resumo O artigo de Lisa Herzog examina como Adam Smith e G. W. F. Hegel conceitualizam a identidade de trabalhadores no mercado. Embora ambos vejam seres humanos como indivíduos formados dentro de relações sociais e por meio delas, a relação entre o trabalhador e seu trabalho é vista por eles de modos diferentes. Para Smith, trabalhadores “possuem” capital humano, enquanto, para Hegel, trabalhadores “são” cervejeiros, açougueiros ou padeiros, pois sua profissão é parte de sua identidade. Essa diferença conceitual, que se reflete em diferentes “variedades de capitalismo” contemporâneas, mostra que não apenas graus, mas também tipos de enraizamento devem ser distinguidos na discussão sobre a relação entre indivíduo e sociedade. O artigo é precedido de uma apresentação feita pelos tradutores. G W F mercado delas possuem “possuem humano enquanto são “são cervejeiros padeiros conceitual variedades capitalismo contemporâneas graus sociedade tradutores
7.
Hepcidin, Interleukin-6 Levels and Iron Metabolism Parameters in Patients with Hepatic Glycogen Storage Diseases: A Cross-Sectional Study Hepcidin Interleukin6 Interleukin 6 Interleukin- Diseases CrossSectional Cross Sectional
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Nalin, Tatiéle
; Sperb-Ludwig, Fernanda
; Siebert, Marina
; Rizowy, Gustavo Mottin
; Weinstein, David A.
; Derks, Terry G. J.
; Souza, Carolina F. M. de
; Schwartz, Ida V. D.
.
Journal of Inborn Errors of Metabolism and Screening
- Métricas do periódico
Abstract Hepatic glycogen storage diseases (GSD) are characterized by recurrent episodes of hypoglycemia, and anemia has been recognized as a frequent complication of these disorders.This was a convenience cross-sectional study to evaluate hepcidin and IL-6 concentrations in patients with hepatic GSD and their association with anemia and other parameters of iron metabolism.Levels of hepcidin, IL-6, and markers of iron metabolism were measured in 32 patients receiving uncooked cornstarch therapy for GSD (GSD Ia= 18; Ib= 7; III= 3; IXa= 3; IXb= 1; median age 9.5 years). IL-6 concentrations were compared to those of 8 individuals heterozygous for GSD. Nine patients were anemic and five patients had hepatic adenomas. IL-6 levels were higher in patients than in heterozygotes. Eight patients had hyperferritinemia, and one had elevated transferrin saturation as well. Hepcidin correlated positively with ferritin levels. IL-6 correlated with hemoglobin, iron, transferrin, and transferrin saturation. There was no correlation between hepcidin and IL-6 levels. Patients with GSD Ib had the highest IL-6 levels.Anemia is a common finding in hepatic GSD, especially in GSD Ib, the type of GSD associated with the highest IL-6 levels. These findings suggest that inflammation is strongly associated with development of anemia in GSD Ib. hypoglycemia disordersThis disorders This crosssectional cross sectional IL6 IL 6 IL- metabolismLevels Levels IL6, 6, 3 Ia 18 7 III IXa IXb 1 95 9 5 9. years. years . years) adenomas heterozygotes hyperferritinemia well hemoglobin levelsAnemia Anemia
8.
Mechanized harvesting of conilon coffee plants using a self-propelled machine
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Souza, Gustavo S. de
; Bouzan, Antônio M. B.
; Infantini, Maurício B.
; Silva, Samuel de A.
; Almeida, Robson F. de
.
Revista Brasileira de Engenharia Agrícola e Ambiental
- Métricas do periódico
RESUMO O café é uma das principais commodities do agronegócio mundial e de grande relevância econômica e social para o Brasil. A falta de mão de obra e seu alto custo são fatores que preocupam os cafeicultores, principalmente na colheita do café conilon, feita manualmente. O objetivo deste trabalho foi avaliar a eficiência de uma colhedora automotriz em diferentes condições de ajuste da máquina e condução da lavoura de café conilon e medir sua influência no custo de colheita comparada a colheita manual. Foram avaliados os fatores velocidade de colheita (800 a 1600 m h-1), rotação do cilindro vibrador de varetas (1,0 e 1,5 RPM), número de ramos ortotrópicos (um, dois e três) e plantas com e sem os ramos plagiotrópicos no terço inferior. O aumento da velocidade de colheita reduziu as eficiências de derriça e de colheita e a desfolha. O aumento de um para três ramos ortotrópicos por planta aumentou as eficiências de colheita e de derriça, a perda de chão e a desfolha e reduziu a carga pendente. O manejo sem os ramos plagiotrópicos apresentou maior eficiência de colheita, menor perda de chão e menor desfolha. As velocidades de colheita de 800 a 1600 m h-1 reduziram os custos totais e unitários em até 62% em relação à colheita manual. O aumento da eficiência de colheita acima de 70% reduziu os custos de colheita em até 79% em relação à colheita manual.
ABSTRACT Coffee is one of the main commodities of global agribusiness and of outstanding economic and social relevance for Brazil. The lack of labor and its high cost are factors that worry coffee producers, mainly during the conilon coffee harvesting, which is performed manually. This study aimed to evaluate the efficiency of a self-propelled harvester under different conditions of machine adjustment and conduction of the Coffea canephora crop and measure its influence on the cost of harvesting compared to manual harvesting. Harvesting speed (800 to 1600 m h-1), rotation of the vibrating rod cylinder (1.0 and 1.5 RPM), number of orthotropic branches (one, two, and three), and plants with and without plagiotropic branches in the lower third were assessed. The increase in harvesting speed reduced the efficiencies of stripping and harvesting and defoliation. Increasing from one to three orthotropic branches per plant increased harvesting and stripping efficiencies, fruit loss on the ground, defoliation, and reduced pending load. The management without plagiotropic branches showed higher harvesting efficiency, lower loss on the ground, and lower defoliation. Harvesting speeds from 800 to 1600 m h-1 reduced the total and unit costs up to 62% compared to manual harvesting. Increasing harvesting efficiency above 70% has reduced harvesting costs by up to 79% compared to manual harvesting.
9.
First record of insect-plant interaction in Late Cretaceous fossils from Nelson Island (South Shetland Islands Archipelago), Antarctica insectplant insect plant South Archipelago, Archipelago , Archipelago)
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SANTOS FILHO, EDILSON B. DOS
; BRUM, ARTHUR S.
; SOUZA, GEOVANE A. DE
; FIGUEIREDO, RODRIGO G.
; USMA, CRISTIAN D.
; RICETTI, JOÃO HENRIQUE Z.
; TREVISAN, CRISTINE
; LEPPE, MARCELO
; SAYÃO, JULIANA M.
; LIMA, FLAVIANA J.
; OLIVEIRA, GUSTAVO R.
; KELLNER, ALEXANDER W.A.
.
Anais da Academia Brasileira de Ciências
- Métricas do periódico
Abstract Despite the enormous paleobotanical record on different islands of the Antarctic Peninsula, the evidence of insect activity associated with fossilized plants is scarce. Here we report the first evidence of insect-plant interaction from Cretaceous deposits, more precisely from a new locality at the Rip Point area, Nelson Island (Antarctic Peninsula). The macrofossil assemblage includes isolated Nothofagus sp. leaf impressions, a common component of the Antarctic paleoflora. Two hundred leaves were examined, of which 15 showed evidence of insect activity, displaying variations in size, shape, and preservation. Two types of interaction damage, galls and mines, were identified. A single specimen retained a circular scar recognized as galling scar, while meandering tracks were considered mines. These traces of herbivore insect activity, correspond to the oldest known record of this type of interaction of West Antarctica and the oldest record of insect-plant interaction in Nothofagus sp. reported so far. Peninsula scarce insectplant plant deposits area Peninsula. . Peninsula) sp impressions paleoflora examined 1 size shape preservation damage mines identified far
10.
Carbon stocks and lability in land use and management systems in southwestern Goiás, Brazil Goiás
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Ribeiro, Diego Oliveira
; Gonçalves, Gabriel Rosa
; Rubio, Giovana Oliveira
; Castoldi, Gustavo
; Vendruscolo, Eduardo Pradi
; Souza, Zaqueu Henrique de
.
RESUMO O sudoeste do estado de Goiás apresenta elevada vocação para diversas atividades agropecuárias, mesmo em solos considerados mais frágeis, como os Neossolos Quartzarênicos. Objetivou-se avaliar os estoques e a labilidade de carbono em sistemas de uso e manejo de um Neossolo Quartzarênico, no sudoeste goiano. Utilizou-se delineamento inteiramente causualizado, constando de áreas submetidas a cinco sistemas de uso e manejo do solo (Cerrado nativo, pastagem intensiva, pastagem extensiva, plantio de soja com sucessão de milho, e eucalipto). Foram coletadas amostras nas profundidades de 0-0,1 e 0,1-0,2 m. Os sistemas de uso e manejo do solo alteraram os estoques e a qualidade do carbono. Na camada de 0-0,2 m, os estoques de carbono variaram entre 15,9 e 29,2 Mg ha−1. As áreas com eucalipto e sob pastejo intensivo proporcionaram incrementos variando entre 72 e 84 % nos estoques de carbono, em relação às áreas de Cerrado e soja-milho. Os teores de carbono nas frações F1, F2 e F4 foram superiores nas áreas com eucalipto e sob pastejo intensivo. Na camada de 0-0,1 m, as áreas com cultivo de eucalipto e sob pastejo intensivo incrementaram o índice de manejo de carbono em 33 e 36 %, respectivamente, quando comparadas à área de referência com Cerrado nativo. agropecuárias frágeis Quartzarênicos Objetivouse Objetivou se Quartzarênico goiano Utilizouse Utilizou causualizado nativo intensiva extensiva milho eucalipto. . eucalipto) 00,1 001 0 0,1 1 0-0, 0,10,2 0102 0,2 2 0,1-0, m 00,2 002 159 15 9 15, 292 29 29, ha1 ha ha−1 7 8 sojamilho. sojamilho milho. soja-milho F1 F 3 respectivamente 00 00, 01 0, 0-0 10 0,10, 010 02 0,1-0 ha− 0- 0,10 0,1-
ABSTRACT The southwest region of the Goiás state, Brazil, is suitable for several agricultural activities, even in more fragile soils such as Typic Quartzipsamments. This study aimed to evaluate the carbon stocks and lability of a Typic Quartzipsamment under land use and management systems in southwestern Goiás. The experiment was conducted in a completely randomized design and consisted of areas subjected to five land use and management systems [native Cerrado vegetation (Brazilian Savanna), pasture under intensive grazing, pasture under extensive grazing, soybean and maize rotation, and eucalyptus]. Soil samples were collected at the 0-0.1 and 0.1-0.2 m layers. The land use and management systems affected the carbon stocks and quality. In the 0-0.2 m layer, the carbon stocks ranged between 15.9 and 29.2 Mg ha−1. The areas with eucalyptus and under intensive grazing promoted increases in the carbon stocks that ranged between 72 and 84 %, when compared to the areas with Cerrado vegetation and soybean and maize rotation. The carbon contents in the F1, F2 and F4 fractions were higher in the areas with eucalyptus and under intensive grazing. In the 0-0.1 m soil layer, the areas with eucalyptus and under intensive grazing had an increase in the carbon management index by 33 and 36 %, respectively, when compared to the reference area with native Cerrado vegetation. state Brazil activities Quartzipsamments Brazilian Savanna, Savanna , Savanna) rotation eucalyptus. . eucalyptus] 00.1 001 0 0.1 1 0-0. 0.10.2 0102 0.2 2 0.1-0. layers quality 00.2 002 layer 159 15 9 15. 292 29 29. ha1 ha ha−1 7 8 % F1 F 3 respectively 00 00. 01 0. 0-0 10 0.10. 010 02 0.1-0 ha− 0- 0.10 0.1-
11.
Influence of nutritional management prior to adaptation to a feedlot diet on ruminal microbiota of Nellore cattle
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Pinto, Ana Carolina Janssen
; Bertoldi, Gustavo Perina
; Felizari, Luana Doretto
; Demartini, Breno Leite
; Dias, Evandro Fernando Ferreira
; Squizatti, Mariana Martins
; Silvestre, Antonio Marcos
; Perna Junior, Flavio
; Mesquita, Lígia Garcia
; Souza, Johnny Maciel
; Rodrigues, Paulo Henrique Mazza
; Cruz, Gustavo D.
; Millen, Danilo Domingues
.
ABSTRACT The objective of this study was to evaluate the effect of either a limited forage intake or concentrate supplementation prior to the adaptation to high-concentrate diets on dry matter intake, ruminal pH, bacteria, and protozoa of Nellore cattle. The experiment was designed as a two 3×3 Latin square, and six cannulated Nellore steers were used. Each experimental period was composed by three feeding phases: pre-adaptation (14 days), adaptation (12 days), and finishing (seven days) diet, in a total of 33 days per period. The steers were assigned to one of three pre-adaptation dietary treatments: control (Tifton hay fed ad libitum + mineral supplement), restriction (Tifton hay fed at 1.4% of BW + mineral supplement), and concentrate (Tifton hay fed ad libitum + 0.5% of BW of a mix of concentrate feedstuffs and mineral supplement). The adaptation period consisted of two adaptation diets, which contained 72 and 79% concentrate for six days each. The finishing diet contained 86% concentrate. During the pre-adaptation phase, restricted cattle had higher pH than concentrate-fed cattle. There was a reduction in M. elsdenii relative population in cattle from either restriction or concentrate groups. During adaptation and finishing phases, cattle from concentrate group had smaller F. succinogenes populations compared with the control group. The previous nutritional backgrounds impact ruminal microbiota during adaptation and finishing phases without causing any negative effect on ruminal pH. Feeding concentrate prior to the adaptation positively impacted the transition to high-concentrate diets and promoted increased dry matter intake. highconcentrate high bacteria 3 3× square used preadaptation pre 14 (1 days, , 12 seven treatments Tifton supplement, supplement supplement) 1 4 1.4 05 0 5 0.5 supplement. . 7 79 each 86 phase concentratefed M groups F ( 1. 0. 8
12.
Copper Binary and Ternary Alloys as Anticorrosive Coatings for Carbon Steel in a Saline Medium
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Souza, Thais Machado de
; Mesquita, Gustavo Dionisio
; Loureiro, Bruno S. M.
; Dias, Lucas Ferreira da Silva
; Lago, Dalva C. B. do
; Senna, Lilian F. de
.
This work compares the anticorrosive properties of DC electrodeposited CuCoNi, CuCo, and CuNi alloy coatings in a NaCl 0.5 mol L-1 solution. The results showed that j and the bath composition influenced the chemical, morphological, and electrochemical characteristics of the alloy coatings. Among all the studied coatings, the CuCo, CuNi, and CuCoNi ones produced at j = 10 A m-2, j = 60 A m-2, and j = 25 A m-2, respectively, showed the best anticorrosive performances in the saline medium, exhibiting charge transfer resistances (Rtc) higher than 2000 Ω cm2 and an electrical double layer capacitances (Cdl) lower than 8 X10-4 F cm-2. These results agree with the compact morphologies and smaller grain sizes presented by these coatings. Therefore, the anticorrosive properties of the coatings cannot be related only to the less noble metal(s) contents in the alloy but also to their morphologies. CuCo 05 0 5 0. L1 L 1 L- solution chemical morphological m2, m2 m 2, 2 m-2 6 respectively medium Rtc (Rtc 200 cm Cdl (Cdl X104 X X10 4 X10- cm2. 2. cm-2 Therefore metals metal s metal(s m- 20 X1 cm-
13.
Synthesis and Evaluation of the Antileishmanial Activity of Novel Eugenol Analogs Containing 1,2,3-Triazole Fragments against Intracellular Leishmania braziliensis 1,2,3Triazole 123Triazole Triazole 1,2,3 1 2 3 3Triazole 123 1,2, 12 1,2 1,
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Evangelista, Roberta S.
; Pereira, Larissa C.
; Souza, Luciana Â. de
; Costa, Adilson V.
; Silva, Danilo A. da
; Oliveira, Fabrício M. de
; Vaz, Boniek G.
; Bressan, Gustavo C.
; Fietto, Juliana L. R.
; Teixeira, Róbson R.
.
Journal of the Brazilian Chemical Society
- Métricas do periódico
This investigation describes the synthesis of eugenol analogs presenting 1,2,3-triazole fragments and evaluation of their antileishmanial activity. The alkylation of guaiacol (1) with allyl bromide afforded 1-(allyloxy)-2-methoxybenzene (2) (93% yield). The Claisen rearrangement conducted with 1 gave ortho eugenol (3) (82% yield). Alkylation procedures performed with 3 produced 1-allyl-3-methoxy-2-(prop-2-yn-1-yloxy)benzene (4) (73% yield) and 1-allyl-3-methoxy-2-(pent-4-yn-1-yloxy)benzene (6) (53% yield). The copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) reactions involving alkynes 4 and 6 with different benzylic azides afforded twenty-two eugenol analogs with 1,2,3-triazole functionalities (48-93% yield). We screened the compounds at 10 μmol L 1 against Leishmania braziliensis intracellular amastigotes during macrophage infection. The action of these compounds was compared with the known leishmanicidal drug amphotericin B. None of the analogs were toxic to macrophages at 10 μmol L-1. The cytotoxic concentration at 50% (CC50), effective concentration at 50% (EC50), and selectivity index (SI) were determined to the best compounds 4-((2-allyl-6-methoxy)phenoxymethyl)-1-(4-chlorobenzyl)-1 H-1,2,3-triazole (8c) and 4-((2-allyl-6-methoxy)phenoxymethyl)-1-(4-trifluoromethoxybenzyl)-1 H-1,2,3-triazole (8h). They showed a significant leishmanicidal effect, with EC50 of 28.09 µmol L-1 (8c) and 52.03 µmol L-1 (8h). The SIs were 9.7 for 8c and > 5.7 for 8h. These compounds have the potential as new leishmanicidal agents against L. braziliensis and may represent a starting point for the development of alternative treatments for cutaneous leishmaniasis. 1,2,3triazole 123triazole triazole 1,2,3 2 activity (1 1allyloxy2methoxybenzene allyloxymethoxybenzene allyloxy methoxybenzene (2 93% 93 (93 yield. yield . (3 82% 82 (82 1allyl3methoxy2prop2yn1yloxybenzene allylmethoxypropynyloxybenzene methoxy prop yn yloxy benzene (4 73% 73 (73 1allyl3methoxy2pent4yn1yloxybenzene allylmethoxypentynyloxybenzene pent (6 53% 53 (53 copperIcatalyzed copper I catalyzed alkyneazide alkyne azide CuAAC (CuAAC twentytwo twenty two 4893% 4893 48 (48-93 infection B L1. L1 1. 50 CC50, CC50 CC , (CC50) EC50, EC (EC50) SI (SI 42allyl6methoxyphenoxymethyl14chlorobenzyl1 allylmethoxyphenoxymethylchlorobenzyl phenoxymethyl chlorobenzyl 4-((2-allyl-6-methoxy)phenoxymethyl)-1-(4-chlorobenzyl)- H1,2,3triazole H123triazole Htriazole H c (8c 42allyl6methoxyphenoxymethyl14trifluoromethoxybenzyl1 allylmethoxyphenoxymethyltrifluoromethoxybenzyl trifluoromethoxybenzyl 4-((2-allyl-6-methoxy)phenoxymethyl)-1-(4-trifluoromethoxybenzyl)- 8h h (8h) effect EC5 2809 28 09 28.0 L- 5203 52 03 52.0 97 9 7 9. 57 5 5. leishmaniasis 3triazole 123 1,2, ( (9 8 (8 yloxybenzene (7 (5 489 (48-9 CC5 (CC50 (EC50 methoxyphenoxymethyl 42allyl6methoxyphenoxymethyl14chlorobenzyl 4-((2-allyl-6-methoxy)phenoxymethyl)-1-(4-chlorobenzyl) H1 42allyl6methoxyphenoxymethyl14trifluoromethoxybenzyl 4-((2-allyl-6-methoxy)phenoxymethyl)-1-(4-trifluoromethoxybenzyl) (8h 280 0 28. 520 52. 12 1,2 (48- (CC5 (EC5 4-((2-allyl-6-methoxy)phenoxymethyl)-1-(4-chlorobenzyl 4-((2-allyl-6-methoxy)phenoxymethyl)-1-(4-trifluoromethoxybenzyl 1, (48 (CC (EC
14.
Model Membranes and Antimicrobial Activities of pH-Sensitive Copolymers pHSensitive pH Sensitive
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Saraiva, Greice K.
; Souza, Valdomiro V. de
; Oliveira, Luciana C. de
; Procópio, Alyne
; Martins, Maisa T.
; Aidar, Isabel N.
; Yi, Ronaldo C. F.
; Lacerda, Caroline D.
; Carretero, Gustavo P B.
; Lira, Rafael B. de
; Riske, Karin A.
; Salinas, Roberto K.
; Chaimovich, Hernan
; Florenzano, Fábio H.
; Cuccovia, Iolanda M.
.
Journal of the Brazilian Chemical Society
- Métricas do periódico
Polymers are options as antimicrobials for skin protection, antifouling surfaces, and fabrics. Here we analyzed the interaction of polymers based on poly(methacrylate) (PMMA) and poly((dimethylamino ethyl) methacrylate) (PDMAEMA) with model membranes and bacteria. We used the homopolymers PMMA, PDMAEMA, and the diblock copolymer(s) prepared with different PMMAm:PDMAEMAn ratios (m/n). The interactions of PDMAEMA and PMMAm-b-PDMAEMAn with large unilamellar vesicles (LUVs) prepared with phosphatidylcholine and phosphatidylglycerol at different pHs, were analyzed by nuclear magnetic resonance (NMR), dynamic light scattering, and zeta potential. These polymers promoted LUVs leakage of a fluorescent probe (5,6-carboxyfluorescein) localized exclusively in the internal aqueous compartment. Interestingly, all copolymers exhibit a bell-shaped pH dependence for the polymer-induced LUVs leakage. The interaction of the positively charged polymers and the pH effect was also demonstrated using giant unilamellar vesicles. These copolymers inhibited bacterial growth in the micromolar range and can be used to prevent bacterial growth on surfaces. protection surfaces fabrics polymethacrylate poly methacrylate poly(methacrylate PMMA (PMMA polydimethylamino dimethylamino ethyl (PDMAEMA bacteria copolymer s copolymer(s PMMAmPDMAEMAn PMMAm PDMAEMAn m/n. mn m/n . m n (m/n) PMMAmbPDMAEMAn b (LUVs pHs NMR, NMR , (NMR) scattering potential 5,6carboxyfluorescein 56carboxyfluorescein carboxyfluorescein 5,6 5 6 (5,6-carboxyfluorescein compartment Interestingly bellshaped bell shaped polymerinduced polymer induced (m/n (NMR 6carboxyfluorescein 56 5,
15.
Agrobacterium rhizogenes-Mediated Transformation of Crotalaria ochroleuca: Production of Flavonoids from Hairy Roots rhizogenesMediated rhizogenes Mediated ochroleuca
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Blank, Daiane E.
; Demuner, Antonio J.
; Carvalho, Jilma L. B.
; Firmino, Maria J. M.
; Figueiredo, Tainá S.
; Souza, Gustavo S. F.
; Zocolo, Guilherme J.
; Guedes, Jhonyson A. C.
; Faria, Daniele V.
; Vieira, Lorena M.
; Soares, Jéssica R.
; Fortini, Evandro A.
; Santos, Marcia A. C.
; Otoni, Wagner C.
.
Journal of the Brazilian Chemical Society
- Métricas do periódico
Crotalaria ochroleuca (Fabaceae) is rich in bioactive compounds used for nematode control. Transformed root culture allows the production of a large amount of hairy root biomass, conditioned by auxin biosynthesis-related genes integrated via the process of Agrobacterium rhizogenes infection, which is known to cause a hairy root phenotype. We transformed A. rhizogenes to increase the biomass of hairy roots and optimized the process of production of bioactive compounds. The transformed nature of hairy roots was confirmed by polymerase chain reaction, which confers kanamycin resistance. The transformed roots were cultured in full-strength in liquid media to realize the growth of hairy roots and the production of bioactive compounds. The transformed roots were grown in a culture medium supplemented with elicitors to produce total phenols, and flavonoids. Chromatographic analysis of transformed roots revealed the presence of flavonoids apigenin-6,8-C-diglucoside and luteolin-6-C-glucoside. The results were obtained by conducting physiological and biochemical studies with the Flavonoids and studying the pathways that led to the production of large amounts of bioactive compounds from the hairy roots of C. ochroleuca. It was observed that the extraction of the compounds significantly affected nematodes and insect larvae, resulting in significantly high levels of economic damage to crops. Fabaceae (Fabaceae control biosynthesisrelated biosynthesis related infection phenotype A reaction resistance fullstrength full strength phenols apigenin6,8Cdiglucoside apigenin68Cdiglucoside apigeninCdiglucoside apigenin 6,8 C diglucoside 6 8 luteolin6Cglucoside. luteolin6Cglucoside luteolinCglucoside luteolin glucoside. glucoside luteolin-6-C-glucoside larvae crops apigenin6 8Cdiglucoside Cdiglucoside 68 6, Cglucoside
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