Resumen Este estudio investiga manifestaciones de microagresiones raciales, con énfasis en medir el trauma racial experimentado por estudiantes negros matriculados en cursos de biblioteconomía. El objetivo general es comprender cómo se manifiestan las microagresiones raciales en este contexto. Los objetivos específicos incluyen: 1) definición conceptual de microagresiones raciales y sus características; 2) categorización de las formas en que estas microagresiones se manifiestan en las interacciones; 3) aplicación de la Escala de Microagresión Racial en la Enseñanza de la Biblioteconomía (EMREB). Desde el punto de vista metodológico, se trata de una investigación aplicada, cualitativa, que utiliza métodos documentales, bibliográficos, exploratorios y descriptivos. El estudio se divide en tres fases: 1) revisión de la literatura; 2) aplicación de cuestionarios y análisis de resultados; 3) desarrollo y aplicación de la escala. El análisis y aplicación de la escala revelan la presencia de microagresiones, que se manifiestan a través de prácticas sutiles, mensajes verbales y no verbales llenos de desprecio, sexismo y racismo, perpetuados por profesores y colegas blancos en el ámbito de la clase. Las microagresiones más frecuentes caen en las categorías de Deslegitimación/Invalidación y Amenaza/Intimidación, y las formas de opresión se cruzan con la opresión de género, racial y sexual en la experiencia educativa de los estudiantes negros en la educación superior. Con la escala, se encontró que las microagresiones raciales tienen consecuencias traumáticas y, junto con las categorías de opresión observadas, tienen un impacto duradero en la vida de los estudiantes negros observados.

Abstract The study investigates manifestations of racial microaggressions, with an emphasis on measuring racial trauma experienced by black students enrolled in Library Science courses. The overall goal is to understand how racial microaggressions manifest in this context. Specific objectives include: a conceptual definition of racial microaggressions and their characteristics; categorization of the ways in which these microaggressions manifest in interactions; and application of the Racial Microaggression Scale in Library Science Education. From a methodological point of view, it is applied qualitative research that uses documentary, bibliographic, exploratory and descriptive methods. The study is divided into three phases: 1) literature review; 2) application of questionnaires and analysis of results; and 3) development and application of the scale. The analysis and application of the scale reveal the presence of microaggressions, which are manifested through subtle practices and verbal and non-verbal messages full of contempt, sexism and racism, perpetuated by white teachers and colleagues in the classroom. The most common microaggressions fall into the categories of Delegitimization/Invalidation and Threat/Intimidation, and forms of oppression intersect with gender, racial, and sexual oppression in the educational experience of black students in higher education. With the scale, racial microaggressions were found to have traumatic consequences and, along with the categories of oppression observed, have a lasting impact on the lives of the Black students observed.

Resumo Neoplasias cardíacas são raras, tendo como principal representante o mixoma atrial (MA), que corresponde a cerca de metade de todos os casos. O MA tem incidência estimada entre 0.001% e 0.3% na população em geral, no entanto apenas aproximadamente 0,06% desses cursam com eventos embólicos coronarianos. Homem de 33 anos, tabagista, admitido com quadro de precordialgia intensa e irradiação para membro superior esquerdo com duração de uma hora. O eletrocardiograma evidenciou elevação de segmento ST nas derivações D2, D3 e aVF troponina sérica elevada, confirmando infarto com supra desnivelamento do segmento ST (IAMCSST). Foi realizada cineangiocoronariografia, a qual revelou oclusão em terço proximal de artéria coronária direita por trombo. Realizada tentativa de aspiração do trombo, sem sucesso, seguido por angioplastia primária com balão sem colocação de stent. Durante a investigação do quadro, paciente realizou ecocardiograma transtorácico o qual demonstrou massa homogênea de superfície regular, de 5.2 cm x 2.3 cm, aderida ao septo interatrial, com lobulações de características emboligênicas prolapsando para valva mitral e ventrículo esquerdo na diástole, compatível com MA. Foi realizada ressecção cirúrgica com paciente evoluindo assintomático, recebendo alta para seguimento ambulatorial. O caso relatado difere em idade e sexo do perfil epidemiológico típico sendo um dos poucos descritos com acometimento da parede inferior apresentando a artéria coronária direita como culpada. Este relato ratifica a importância do diagnóstico diferencial frente às apresentações de IAMCSST em jovens. raras MA, , (MA) casos 0001 0 001 0.001 03 3 0.3 geral 006 06 0,06 coronarianos anos tabagista hora D2 D elevada IAMCSST. . (IAMCSST) cineangiocoronariografia trombo sucesso stent regular 52 5 2 5. 23 2. interatrial diástole assintomático ambulatorial culpada jovens (MA 000 00 0.00 0. 0,0 (IAMCSST 0.0 0,

Abstract Cardiac tumors are rare entities, among which atrial myxoma (AM) stands as the most frequent, accounting for approximately half of all reported cases. The incidence of AM is estimated to range from 0.001% to 0.3% within the general population, yet only about 0.06% of these cases present with coronary embolic events. We report on a 33-year-old male smoker who experienced acute, severe precordial pain radiating to the left upper limb, lasting for one hour. The electrocardiographic evaluation demonstrated ST-segment elevation in leads D2, D3, and aVF, alongside significantly elevated serum troponin levels, confirming a diagnosis of ST-segment elevation myocardial infarction (STEMI). Subsequent coronary angiography revealed proximal occlusion of the right coronary artery due to thrombus. An initial attempt of thrombus aspiration was unsuccessful, followed by primary angioplasty with balloon inflation without stent placement. Further diagnostic exploration through transthoracic echocardiography identified a homogenous, smooth-surfaced mass measuring 5.2 cm x 2.3 cm attached to the interatrial septum. This mass, characterized by lobulations, prolapsed into the mitral valve and left ventricle during diastole, consistent with AM. Surgical resection of the mass was successfully performed, with the patient being discharged asymptomatic. In the reported case, the patient's profile, notably his age, and gender, diverges from the typical epidemiological characteristics associated with AM. This case adds to the limited number of reports where the inferior wall is affected by the right coronary artery being occluded. This report emphasizes the significance of differential diagnoses in younger patients presenting with STEMI. entities (AM frequent 0001 0 001 0.001 03 3 0.3 population 006 06 0.06 events 33yearold yearold 33 year old acute limb hour STsegment ST segment D2 D D3 aVF levels STEMI . (STEMI) unsuccessful placement homogenous smoothsurfaced smooth surfaced 52 5 2 5. 23 2. septum lobulations diastole performed asymptomatic s profile age gender occluded 000 00 0.00 0. 0.0 (STEMI

Abstract Background: The bioactive peptides derived from snake venoms of the Viperidae family species have been promising as therapeutic candidates for neuroprotection due to their ability to prevent neuronal cell loss, injury, and death. Therefore, this study aimed to evaluate the cytoprotective effects of a synthetic proline-rich oligopeptide 7a (PRO-7a; <EDGPIPP) from Bothrops jararaca snake, on oxidative stress-induced toxicity in neuronal PC12 cells and astrocyte-like C6 cells. Methods: Both cells were pre-treated for four hours with different concentrations of PRO-7a, submitted to H2O2-induced damage for 20 h, and then the oxidative stress markers were analyzed. Also, two independent neuroprotective mechanisms were investigated: a) L-arginine metabolite generation via argininosuccinate synthetase (AsS) activity regulation to produce agmatine or polyamines with neuroprotective properties; b) M1 mAChR receptor subtype activation pathway to reduce oxidative stress and neuron injury. Results: PRO-7a was not cytoprotective in C6 cells, but potentiated the H2O2-induced damage to cell integrity at a concentration lower than 0.38 μM. However, PRO-7a at 1.56 µM, on the other hand, modified H2O2-induced toxicity in PC12 cells by restoring cell integrity, mitochondrial metabolism, ROS generation, and arginase indirect activity. The α-Methyl-DL-aspartic acid (MDLA) and L-NΩ-Nitroarginine methyl ester (L-Name), specific inhibitors of AsS and nitric oxide synthase (NOS), which catalyzes the synthesis of polyamines and NO from L-arginine, did not suppress PRO-7a-mediated cytoprotection against oxidative stress. It suggested that its mechanism is independent of the production of L-arginine metabolites with neuroprotective properties by increased AsS activity. On the other hand, the neuroprotective effect of PRO-7a was blocked in the presence of dicyclomine hydrochloride (DCH), an M1 mAChR antagonist. Conclusions: For the first time, this work provides evidence that PRO-7a-induced neuroprotection seems to be mediated through M1 mAChR activation in PC12 cells, which reduces oxidative stress independently of AsS activity and L-arginine bioavailability. Background loss injury death Therefore prolinerich proline rich PRO7a PROa PRO (PRO-7a <EDGPIPP EDGPIPP stressinduced induced PC PC1 astrocytelike astrocyte like C Methods pretreated pre treated PRO7a, 7a, H2O2induced HOinduced H2O2 H O 2 h analyzed Also investigated Larginine L arginine (AsS b M Results 038 0 38 0.3 μM However 156 1 56 1.5 µM hand metabolism αMethylDLaspartic α Methyl DL aspartic MDLA (MDLA LNΩNitroarginine NΩ Nitroarginine LName, LName Name , (L-Name) NOS, NOS (NOS) Larginine, arginine, PRO7amediated PROamediated DCH, DCH (DCH) antagonist Conclusions time PRO7ainduced PROainduced bioavailability HO H2O 03 3 0. 15 5 1. (L-Name (NOS amediated (DCH ainduced

ABSTRACT The objective of the current study was to investigate the effects of different levels of andiroba oil (AO) in a bioproduct based on andiroba oil (BBAO) on the physical quality, bacteriological concentration, chemical composition, yolk lipid oxidation, and sensory characteristics when coating eggs and storing them for seven days at room temperature. The eggs were arranged in a completely randomized design, in which treatments consisted of a control group (eggs stored for seven days without the application of BBAO) and eggs covered with biofilms produced with BBAO with different levels of AO (1%, 5%, 10%, and 15%). Each treatment contained 50 eggs, and each egg was considered a replicate. Data collected were subjected to Tukey test and linear or polynomial regression at 0.05 statistical significance. The results indicate that the application of BBAO on eggs stored for 7 days at room temperature resulted in better (p<0.05) conservation of their physical quality and chemical composition, and a reduction (p<0.05) or elimination of bacteriological concentrations. This conservation effect became increasingly pronounced as the concentration of AO in the BBAO increased. However, it is crucial to consider the implications of BBAO on sensory characteristics, as higher concentrations of AO in BBAO lead to a decreased (p<0.05) sensory acceptance of the eggs. Therefore, it was concluded that the use of AO in the bioproduct, especially at high levels, can provide better conservation of the eggs for seven days at room temperature, particularly concerning the physical, chemical, and microbiological characteristics; however, it can also cause significant changes in sensory attributes. (AO (BBAO composition oxidation design 1%, 1 (1% 5 5% 10 10% 15%. 15 15% . 15%) replicate 005 0 05 0.0 significance p<0.05 p005 p (p<0.05 increased However Therefore however attributes 1% (1 00 0. p<0.0 p00 (p<0.0 ( p<0. p0 (p<0. p<0 (p<0 p< (p< (p

RESUMO: O conceito de colonialidade repercute a presença dos padrões racistas de poder do colonialismo na realidade contemporânea. Tendo por base a Epistemologia das Macumbas e a Pedagogia das Encruzilhadas - pensadas por Luiz Rufino e Luiz Antônio Simas -, propomos o ensino encantado de ciências: uma possibilidade de transgressão da colonialidade por meio do ensino de ciências. Primeiro, posicionamos a obra de Simas e Rufino dentro do pensamento decolonial. Em seguida, discutimos os fundamentos da Epistemologia das Macumbas e da Pedagogia das Encruzilhadas, com destaque para os conceitos de encantamento e cruzo. Como conclusão, propomos o ensino encantado de ciências como projeto pautado na crítica à ocidentalidade e na construção da interculturalidade a partir das macumbas brasileiras. RESUMO contemporânea , Primeiro decolonial seguida cruzo conclusão brasileiras

ABSTRACT: coloniality is a concept that reflects colonialist power's racist patterns in contemporary context. Drawing on the Epistemology of the Brazilian Macumbas and the Pedagogy of Crossroads, formulated by Luiz Rufino and Luiz Antônio Simas, we advocate for an “enchanted” approach to science teaching: an opportunity to transcend coloniality through science education. Initially, we situate the works of the authors Simas and Rufino within decolonial thought. Subsequently, we explore the underpinnings of the Epistemology of the Brazilian Macumbas Practices and the Pedagogy of Crossroads, emphasizing the notions of “enchantment” and crossroads. We conclude the article by proposing a perspective called “enchanted” teaching of science based on critiquing western-centricity and fostering interculturality. ABSTRACT powers power s context Crossroads enchanted “enchanted education Initially thought Subsequently enchantment “enchantment crossroads westerncentricity western centricity interculturality

RESUMEN: El concepto de colonialidad refleja la presencia de los patrones de poder racistas del colonialismo en la realidad contemporánea. A partir de la Epistemología de las Macumbas y de la Pedagogía de las Encrucijadas en el pensamiento de Luiz Rufino y Luiz Antônio Simas, este estudio propone una enseñanza encantada de las ciencias, una posibilidad de transgresión de la colonialidad a través de la enseñanza de las Ciencias. Primero, se posiciona el trabajo de Simas y Rufino dentro del pensamiento decolonial, seguido de una discusión sobre los fundamentos de la Epistemología de las Macumbas y la Pedagogía de las Encrucijadas, centrándose en los conceptos de encantamiento y cruzo. El estudio concluye proponiendo la enseñanza encantada de las ciencias como un proyecto basado en una crítica a la occidentalidad y en la construcción de la interculturalidad a partir de las macumbas brasileñas. RESUMEN contemporánea Ciencias Primero decolonial cruzo brasileñas

RESUMO Objetivo: Identificar estratégias de promoção da saúde utilizadas por gestores na atenção primária à saúde. Método: Pesquisa qualitativa, de natureza ação participante, que adotou como referencial metodológico o Círculo de Cultura proposto por Paulo Freire. Participaram 11 gestores da atenção primária à saúde de um município de médio porte do sul do Brasil. Resultados: Surgiram nove temas geradores categorizados em quatro temáticas que evidenciam a interconexão entre promoção da saúde, determinantes sociais e atenção primária à saúde. Essas temáticas destacam abordagens preventivas, hábitos saudáveis e sublinham a necessidade de uma abordagem multidisciplinar na atenção à saúde, reconhecendo a complexidade das dimensões envolvidas, a influência dos determinantes sociais, questões ambientais e sanitárias. Tais aspectos demandam políticas e ações intersetoriais, evidenciando a viabilidade da promoção da saúde alinhada aos princípios do Sistema Único de Saúde. Considerações Finais: Destaca-se a autonomia dos profissionais que atuam em serviços de atenção primária à saúde, especialmente a do enfermeiro, que desempenha um papel central na conectividade e ordenação das ações de promoção da saúde. Objetivo Método qualitativa participante Freire 1 Brasil Resultados preventivas envolvidas sanitárias intersetoriais Saúde Finais Destacase Destaca se enfermeiro

ABSTRACT Objective: To identify health promotion strategies used by managers in primary health care. Method: Qualitative research, of a participant action nature, which adopted the Culture Circle proposed by Paulo Freire as its methodological reference. Eleven primary health care managers from a medium-sized municipality in southern Brazil took part. Results: Nine generative themes emerged, categorized into four themes that highlight the interconnection between health promotion, social determinants and primary health care. These themes highlight preventive approaches, healthy habits and underline the need for a multidisciplinary approach to health care, recognizing the complexity of the dimensions involved, the influence of social determinants, environmental and health issues. These aspects call for intersectoral policies and actions, demonstrating the viability of health promotion in line with the principles of the Unified Health System. Final considerations: The autonomy of professionals working in primary health care services is highlighted, especially that of nurses, who play a central role in connecting and organizing health promotion actions. Objective Method research nature reference mediumsized medium sized part Results emerged approaches involved issues actions System considerations highlighted nurses

RESUMEN Objetivo: Identificar las estrategias de promoción de la salud utilizadas por gestores en la atención primaria de salud. Método: Investigación cualitativa, de tipo acción participante, que adoptó como referencia metodológica el Círculo de Cultura propuesto por Paulo Freire. Participaron 11 gestores de atención primaria de salud de un municipio de tamaño medio del sur de Brasil. Resultados: Surgieron nueve temas generativos, categorizados en cuatro temáticas que destacan la interconexión entre la promoción de la salud, los determinantes sociales y la atención primaria de salud. Estos temas destacan los enfoques preventivos, los hábitos saludables y subrayan la necesidad de un enfoque multidisciplinar de la atención sanitaria, reconociendo la complejidad de las dimensiones implicadas, la influencia de los determinantes sociales y las cuestiones medioambientales y sanitarias. Estos aspectos exigen políticas y acciones intersectoriales, demostrando la viabilidad de la promoción de la salud en consonancia con los principios del Sistema Único de Salud. Consideraciones finales: Se destaca la autonomía de los profesionales que actúan en los servicios de atención primaria de salud, especialmente la de las enfermeras, que desempeñan un papel central en la conectividad y organización de las acciones de promoción de la salud. Objetivo Método cualitativa participante Freire 1 Brasil Resultados generativos preventivos sanitaria implicadas sanitarias intersectoriales Salud finales enfermeras

Abstract Background Giant cell arteritis (GCA) is the most common primary systemic vasculitis in people 50 years of age and over, and it is considered a medical emergency due to the potential risk of permanent visual loss. Color Doppler ultrasound (CDU) of the temporal arteries is a rapid, noninvasive method to diagnose GCA. This study aims to determine the diagnostic accuracy of the halo sign in temporal arteries by CDU in people with suspected GCA. Methods The systematic literature review included the search for publications in the following electronic databases: PubMed, Embase, CENTRAL, LILACS, WHO ICTRP, ClinicalTrials.gov, gray literature up to December 2022, and no date or language restrictions were applied. We analyzed studies including patients over 50 years of age with suspected GCA evaluating CDU of temporal arteries as a diagnostic tool against clinical diagnosis as a standard reference. Paper titles and abstracts were selected by two investigators independently for all available records. The quality of the studies was assessed using the Quality of Diagnostic Accuracy Studies tool (QUADAS-2) and the R software (version 4.2.1) was used for data analysis. The protocol of this review is registered with PROSPERO (CRD42016033079). Results Twenty-two studies including 2893 participants with suspected GCA who underwent temporal artery CDU were evaluated. The primary analysis results showed a sensitivity of 0.76 [95% confidence interval (95 CI) 0.69–0.81] and specificity of 0.93 (95 CI 0.89–0.95) when the halo sign was compared to clinical diagnosis. The sensitivity value of 0.84 (95 CI 0.72–0.92) and specificity of 0.95 (95 CI 0.88–0.98) were found in five studies involving 1037 participants that analyzed the halo sign and temporal artery compression sign. A sensitivity of 0.86 (95 CI 0.78–0.91) and specificity of 0.95 (95 CI 0.89–0.98) were found in four studies with 603 participants where the halo sign was evaluated CDU on temporal and axillary arteries. Conclusion The detection of the halo sign by CDU of temporal arteries has good accuracy for the diagnosis of cranial GCA. The compression sign in temporal arteries and the addition of axillary arteries assessment improves the diagnostic performance of CDU for GCA. Trial registration PROSPERO CRD42016046860. (GCA 5 loss (CDU rapid databases PubMed Embase CENTRAL LILACS ICTRP ClinicalTrialsgov ClinicalTrials gov ClinicalTrials.gov 2022 applied reference records QUADAS2 QUADAS 2 (QUADAS-2 version 4.2.1 421 4 1 CRD42016033079. CRD42016033079 CRD . (CRD42016033079) Twentytwo Twenty 289 076 0 76 0.7 95% 95 [95 (9 0.69–0.81 069081 69 81 093 93 0.9 0.89–0.95 089095 89 084 84 0.8 0.72–0.92 072092 72 92 095 0.88–0.98 088098 88 98 103 086 86 0.78–0.91 078091 78 91 0.89–0.98 089098 60 CRD42016046860 202 (QUADAS- 4.2. 42 CRD4201603307 (CRD42016033079 28 07 7 0. 9 [9 ( 0.69–0.8 06908 6 8 09 0.89–0.9 08909 08 0.72–0.9 07209 0.88–0.9 08809 10 0.78–0.9 07809 CRD4201604686 20 (QUADAS 4.2 CRD420160330 (CRD4201603307 [ 0.69–0. 0690 0.89–0. 0890 0.72–0. 0720 0.88–0. 0880 0.78–0. 0780 CRD420160468 4. CRD42016033 (CRD420160330 0.69–0 069 0.89–0 089 0.72–0 072 0.88–0 088 0.78–0 078 CRD42016046 CRD4201603 (CRD42016033 0.69– 06 0.89– 0.72– 0.88– 0.78– CRD4201604 CRD420160 (CRD4201603 0.69 0.89 0.72 0.88 0.78 CRD42016 (CRD420160 0.6 CRD4201 (CRD42016 CRD420 (CRD4201 CRD42 (CRD420 CRD4 (CRD42 (CRD4 (CRD

Resumo Fundamento A Insuficiência Cardíaca é um importante problema de saúde pública, que leva à alta carga de sintomas físicos e psicológicos, apesar da terapia otimizada. Objetivo Avaliar primariamente o impacto de um Programa de Redução de Estresse, Meditação e Atenção plena na redução do estresse de pacientes com Insuficiência Cardíaca. Métodos Ensaio clínico randomizado e controlado que avaliou o impacto de um programa de redução de estresse comparado ao atendimento multidisciplinar convencional, em dois centros especializados no Brasil. O período de coleta de dados ocorreu entre abril e outubro de 2019. Um total de 38 pacientes foram alocados nos grupos de intervenção ou controle. A intervenção aconteceu ao longo de 8 semanas. O protocolo consistiu na avaliação das escalas de estresse percebido, depressão, qualidade de vida, ansiedade, atenção plena, qualidade do sono, teste de 6 minutos de caminhada e biomarcadores por um grupo cego, considerando um p-valor <0,05 como estatisticamente significativo. Resultados A intervenção resultou em redução significativa no estresse percebido de 22,8 ± 4,3 para 14,3 ± 3,8 pontos na escala de estresse percebido no grupo de intervenção vs. 23,9 ± 4,3 para 25,8 ± 5,4 no grupo controle (p-valor<0,001). Foi observada melhora significativa na qualidade de vida (p-valor=0,013), atenção plena (p-valor=0,041), qualidade do sono (p-valor<0,001) e no teste de 6 minutos de caminhada (p-valor=0,004) no grupo sob intervenção comparado com o controle. Conclusão O Programa de Redução de Estresse, Meditação e Atenção plena reduziu efetivamente o estresse percebido e melhorou desfechos clínicos em pacientes com Insuficiência Cardíaca. pública psicológicos otimizada Estresse convencional Brasil 2019 3 semanas depressão ansiedade cego pvalor p valor 005 0 05 <0,0 significativo 228 22 22, 43 4 4, 143 14 14, 3, vs 239 23 9 23, 258 25 25, 54 5 5, pvalor<0,001. pvalor0001 valor<0,001 . 001 pvalor=0,013, pvalor0013 valor=0,013 , 013 (p-valor=0,013) pvalor=0,041, pvalor0041 valor=0,041 041 (p-valor=0,041) pvalor<0,001 (p-valor<0,001 pvalor=0,004 pvalor0004 valor=0,004 004 (p-valor=0,004 201 00 <0, 2 1 pvalor000 valor0001 valor<0,00 pvalor=0,013 pvalor001 valor0013 valor=0,01 01 (p-valor=0,013 pvalor=0,041 pvalor004 valor0041 valor=0,04 04 (p-valor=0,041 pvalor<0,00 (p-valor<0,00 pvalor=0,00 valor0004 valor=0,00 (p-valor=0,00 20 <0 pvalor00 valor000 valor<0,0 pvalor=0,01 valor001 valor=0,0 (p-valor=0,01 pvalor=0,04 valor004 (p-valor=0,04 pvalor<0,0 (p-valor<0,0 pvalor=0,0 (p-valor=0,0 < pvalor0 valor00 valor<0, valor=0, pvalor<0, (p-valor<0, pvalor=0, (p-valor=0, valor0 valor<0 valor=0 pvalor<0 (p-valor<0 pvalor=0 (p-valor=0 valor< valor= pvalor< (p-valor< pvalor= (p-valor= (p-valor

Abstract Background Heart Failure is a significant public health problem leading to a high burden of physical and psychological symptoms despite optimized therapy. Objective To evaluate primarily the impact of a Stress Reduction, Meditation, and Mindfulness Program on stress reduction of patients with Heart Failure. Methods A randomized and controlled clinical trial assessed the effect of a stress reduction program compared to conventional multidisciplinary care in two specialized centers in Brazil. The data collection period took place between April and October 2019. Thirty-eight patients were included and allocated to the intervention or control groups. The intervention took place over 8 weeks. The protocol assessed the scales of perceived stress, depression, quality of life, anxiety, mindfulness, quality of sleep, a 6-minute walk test, and biomarkers analyzed by a blinded team, considering a p-value <0.05 statistically significant. Results The intervention resulted in a significant reduction in perceived stress from 22.8 ± 4.3 to 14.3 ± 3.8 points in the perceived stress scale-14 items in the intervention group vs. 23.9 ± 4.3 to 25.8 ± 5.4 in the control group (p-value<0.001). A significant improvement in quality of life (p-value=0.013), mindfulness (p-value=0.041), quality of sleep (p-value<0.001), and the 6-minute walk test (p-value=0.004) was also observed in the group under intervention in comparison with the control. Conclusion The Stress Reduction, Meditation, and Mindfulness Program effectively reduced perceived stress and improved clinical outcomes in patients with chronic Heart Failure. therapy Reduction Meditation Brazil 2019 Thirtyeight Thirty eight groups weeks depression anxiety 6minute minute 6 team pvalue p value 005 0 05 <0.0 228 22 22. 43 4 3 4. 143 14 14. 38 3. scale14 scale scale-1 vs 239 23 9 23. 258 25 25. 54 5 5. pvalue<0.001. pvalue0001 value<0.001 . 001 (p-value<0.001) pvalue=0.013, pvalue0013 value=0.013 , 013 (p-value=0.013) pvalue=0.041, pvalue0041 value=0.041 041 (p-value=0.041) pvalue<0.001, pvalue=0.004 pvalue0004 value=0.004 004 (p-value=0.004 201 00 <0. 2 1 scale1 scale- pvalue<0.001 pvalue000 value0001 value<0.00 (p-value<0.001 pvalue=0.013 pvalue001 value0013 value=0.01 01 (p-value=0.013 pvalue=0.041 pvalue004 value0041 value=0.04 04 (p-value=0.041 pvalue=0.00 value0004 value=0.00 (p-value=0.00 20 <0 pvalue<0.00 pvalue00 value000 value<0.0 (p-value<0.00 pvalue=0.01 value001 value=0.0 (p-value=0.01 pvalue=0.04 value004 (p-value=0.04 pvalue=0.0 (p-value=0.0 < pvalue<0.0 pvalue0 value00 value<0. (p-value<0.0 value=0. pvalue=0. (p-value=0. pvalue<0. value0 value<0 (p-value<0. value=0 pvalue=0 (p-value=0 pvalue<0 value< (p-value<0 value= pvalue= (p-value= pvalue< (p-value< (p-value

ABSTRACT BACKGROUND: Artificial intelligence (AI) deals with development of algorithms that seek to perceive one’s environment and perform actions that maximize one’s chance of successfully reaching one’s predetermined goals. OBJECTIVE: To provide an overview of the basic principles of AI and its main studies in the fields of glaucoma, retinopathy of prematurity, age-related macular degeneration and diabetic retinopathy. From this perspective, the limitations and potential challenges that have accompanied the implementation and development of this new technology within ophthalmology are presented. DESIGN AND SETTING: Narrative review developed by a research group at the Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil. METHODS: We searched the literature on the main applications of AI within ophthalmology, using the keywords “artificial intelligence”, “diabetic retinopathy”, “macular degeneration age-related”, “glaucoma” and “retinopathy of prematurity,” covering the period from January 1, 2007, to May 3, 2021. We used the MEDLINE database (via PubMed) and the LILACS database (via Virtual Health Library) to identify relevant articles. RESULTS: We retrieved 457 references, of which 47 were considered eligible for intensive review and critical analysis. CONCLUSION: Use of technology, as embodied in AI algorithms, is a way of providing an increasingly accurate service and enhancing scientific research. This forms a source of complement and innovation in relation to the daily skills of ophthalmologists. Thus, AI adds technology to human expertise.

The coloniality concept reflects the presence of colonialism's racist power patterns in contemporary reality. Based on Macumbas Epistemology and Crossroads Pedagogy as thought by Luiz Rufino and Luiz Antônio Simas, this study proposes an enchanted science teaching, a possibility of coloniality transgression through science teaching. First, Simas and Rufino’s work is positioned within decolonial thought, followed by a discussion on the foundations of Macumbas Epistemology and Crossroads Pedagogy, focusing on the enchantment and cruzo concepts. The study concludes by proposing enchanted science teaching as a project based on a westernity critique and on interculturality construction based on Brazilian macumbas.

El concepto de colonialidad refleja la presencia de los patrones de poder racistas del colonialismo en la realidad contemporánea. A partir de la Epistemología de las Macumbas y de la Pedagogía de la Encrucijada en el pensamiento de Luiz Rufino y Luiz Antônio Simas, este estudio propone una enseñanza de las ciencias encantada, una posibilidad de transgresión de la colonialidad a través de la enseñanza de las ciencias. Primero, se posiciona el trabajo de Simas y Rufino dentro del pensamiento decolonial, seguido de una discusión sobre los fundamentos de la Epistemología de las Macumbas y la Pedagogía de la Encrucijada, centrándose en los conceptos de encantamiento y cruzo. El estudio concluye proponiendo la enseñanza de las ciencias encantadas como un proyecto basado en una crítica a la occidentalidad y en la construcción de la interculturalidad a partir de las macumbas brasileñas.

O conceito de colonialidade repercute a presença dos padrões racistas de poder do colonialismo na realidade contemporânea. Baseado na Epistemologia das Macumbas e na Pedagogia das Encruzilhadas - pensadas por Luiz Rufino e Luiz Antônio Simas, este trabalho propõe o ensino encantado de ciências: uma possibilidade de transgressão da colonialidade por meio do ensino de Ciências. Primeiro, posiciona-se a obra de Simas e Rufino dentro do pensamento decolonial. Em seguida, são discutidos os fundamentos da Epistemologia das Macumbas e da Pedagogia das Encruzilhadas, com destaque para os conceitos de encantamento e cruzo. Conclui-se propondo o ensino encantado de ciências como projeto pautado na crítica à ocidentalidade e na construção da interculturalidade a partir das macumbas brasileiras.

Resumo A expansão do cultivo de mogno-africano no Brasil, assim como outras espécies exóticas, implica sua exposição a variadas condições climáticas e ambientais, remetendo ao surgimento de pragas e doenças até então não relatadas na literatura. Nesse sentido, o objetivo deste estudo foi registrar a primeira ocorrência de Naupactus optatus (Herbst, 1797) (Coleoptera: Curculionidae) em mogno-africano no Brasil. Amostras suspeitas foram coletadas infestando raízes, folhas, ramos e hastes de plantas de mogno-africano em uma fazenda no município de Cantá, Roraima, Brasil. O material amostrado continha besouros curculionídeos, em todas as fases de desenvolvimento, ovos, larvas e adultos, machos e fêmeas, os quais foram identificados como Naupactus optatus (Herbst, 1797) (Coleoptera: Curculionidae). As folhas atacadas apresentavam, nos seus bordos e/ou entre as nervuras, recortes semicirculares, deixando-as com aspecto serrilhado e/ou com o aspecto de meia lua. As plantas ficaram totalmente desfolhadas, fazendo surgir excesso de brotações laterais no tronco e ao longo do caule. Este é o primeiro registro de Naupactus optatus (Coleoptera: Curculionidae) em mogno-africano no Brasil.

Abstract The expansion of african mahogany cultivation in Brazil, as well as other exotic species, implies its exposure to various climatic and environmental conditions, referring to the appearance of pests and diseases not previously reported in the literature. In this sense, the objective of this study was to record the first occurrence of Naupactus optatus (Herbst, 1797) (Coleoptera: Curculionidae) in african mahogany in Brazil. Suspicious samples were collected infesting roots, leaves, branches and stems of African mahogany plants on a farm in the municipality of Cantá, Roraima, Brazil. The sampled material includes curculionids, in all stages of development, eggs, larvae and adults, males and females, which were identified as Naupactus optatus (Herbst, 1797) (Coleoptera: Curculionidae). The attacked leaves were semicircular in their edges and/or between the ribs, leaving them with a serrated appearance and/or with the appearance of a half moon. The plants were completely defoliated, causing excess side shoots to appear on the trunk and along the stem. This is the first record by Naupactus optatus (Coleoptera: Curculionidae) on african mahogany in Brazil.

RESUMO Quais os enfoques na produção científica do campo biblioteconômico-informacional vinculam a competência em informação e a justiça social para população negra? Esta é a problemática que este artigo visa responder, e para o qual o objetivo geral está em refletir sobre a justiça social e a população negra, sob a lente teórica da Competência em Informação. Trata-se de um estudo teórico, de cunho bibliográfico e documental, que possui como base artigos, livros, capítulos de livros e outros recursos informacionais coletados na literatura científica em Biblioteconomia e Ciência da Informação (BCI). A reflexão teórica está estruturada pela discussão sobre competência em informação para uma ação social, promoveu uma cartografia das discussões sobre capitalismo, globalização e capitalismo racial enquanto instrumentos de injustiça às pessoas negras e outras não-brancas, e, por fim, trouxe quatro estratégias que compõem a teoria da justiça social para pessoas negras, a partir do olhar para competência em informação.

ABSTRACT What approaches in scientific production in the librarianship-informational field link information competence and social justice for the black population? This is the problem that this article aims to answer, and for which the general objective is to reflect on social justice and the black population, under the theoretical lens of Information Competence. This work is a theoretical, bibliographic and documentary study, which is based on articles, books, book chapters and other information resources collected in the scientific literature in Librarianship and Information Science (LIS). The theoretical reflection is structured by the discussion about information literacy for social action, promoted a cartography of the discussions about capitalism, globalization and racial capitalism as instruments of injustice to black and other non-white people, and, finally, brought four strategies that compose the theory of social justice for black people, from the point of view of information literacy.

ABSTRACT Objective To analyze the most common ophthalmologic disorders in pregnant women seen in a hospital in Munich in Germany using a big data analysis system, as well as to compare the results obtained with those from other epidemiological studies that used different data acquisition methods. Methods We retrospectively analyzed electronic health records of pregnant women who were seen at the ophthalmology department from 2003 to 2019 at the Ludwig-Maximilians-Universität München hospital. The main complaints that led to ophthalmic consultations during this period were evaluated, and also the variation in intraocular pressure of patients throughout gestational trimesters by analyzing data from the data warehouse system. Results A total of 27,326 electronic health records were analyzed. Of participants, 149 (0.54%) required eye care during pregnancy. Their mean intraocular pressure was 17mmHg in the first trimester, 12mmHg in the second trimester, and 14mmHg in the third trimester. The most prevalent findings were dry eye (29.3%) and conjunctivitis (16%), and ametropia (16%). The most common posterior segment problem was diabetic retinopathy (4.6%). The lower mean intraocular pressure in the second and third trimester found in our study is in accordance with other studies that used other method for data acquisition. Conclusion The most common ophthalmic conditions found in this study population were dry eye, conjunctivitis, and ametropia. The use of data warehouse proved to be useful for acquiring and analyzing data from many patients. This study results are comparable with other studies in published literature that adopted different methodology.