ABSTRACT: The study was conducted on a 3-year-old female Santa Inês sheep from a property located in the municipality of Santo Antônio de Tauá, west of Pará. The affected animal had a history of exophthalmos in the left eye, nasal discharge, and breathing difficulty for more than three months. On physical examination, the animal had a low body score, apathy, unilateral facial asymmetry, moderate unilateral left exophthalmos, mixed dyspnea and unilateral profuse serosanguinous nasal discharge. At necropsy, a large nasal mass was observed, predominantly yellowish-white with blackish-red areas, with an irregular, finely granular, moist, and friable surface. The mass invaded from the mucocutaneous junction of the left nostril to the choanae, infiltrated the frontal sinuses, the cribiform plate, and reached the meninges and the frontal portion of the brain. Microscopy of the surface of the nasal epithelium showed severe destruction of the turbinates and epithelia, evidenced by extensive areas of necrosis with a large amount of cellular debris, ulceration, and secondary bacterial infection. In the central nervous system there was pyogranulomatous meningitis with marked vessel congestion, as well as foci of necrosis and granulomatous inflammation. Immunohistochemistry showed intense staining of numerous intralesional hyphae for antibodies against Conidiobolus lamprauges. The diagnosis of granulomatous rhinitis of mycotic origin associated with the Conidiobolus lamprauges was based on epidemiological, clinical-pathological, and immunohistochemical data. ABSTRACT 3yearold yearold 3 year old Tauá Pará eye discharge months examination score apathy asymmetry necropsy observed yellowishwhite yellowish white blackishred blackish red irregular granular moist choanae sinuses plate brain epithelia debris ulceration infection congestion inflammation epidemiological clinicalpathological, clinicalpathological clinical pathological, pathological clinical-pathological data

RESUMO: O estudo foi realizado em um ovino, fêmea, de três anos de idade, da raça santa inês, procedente de uma propriedade localizada do município de Santo Antônio de Tauá, oeste do Pará. O animal acometido tinha histórico de exoftalmia no olho esquerdo, secreção nasal e dificuldade respiratória há mais de três meses. Ao exame físico o animal apresentava baixo escore corporal, apatia, assimetria facial unilateral, moderada exoftalmia unilateral esquerda, dispneia mista e exsudação nasal serossanguinolenta profusa unilateral. À necropsia, foi observada grande massa nasal, predominantemente branco-amarelada com áreas vermelho enegrecidas, de superfície irregular, finamente granular, úmida e friável. A massa invadia desde a junção mucocutânea do nariz esquerdo até as coanas, se infiltrava pelos seios nasais frontais, placa cribiforme e alcançava as meninges e a porção frontal do cérebro. À microscopia da superfície do epitélio nasal notou-se severa destruição dos cornetos e dos epitélios, evidenciada por extensas áreas de necrose com muitos debris celulares, ulceração e infecção bacteriana secundária. No sistema nervoso central (SNC) havia meningite piogranulomatosa com acentuada congestão de vasos, focos de necrose e inflamação granulomatosa. O diagnóstico de rinite granulomatosa de origem micótica associada ao fungo Conidiobolus lamprauges foi baseado nos achados da imuno-histoquímica. RESUMO ovino fêmea idade inês Tauá Pará meses corporal apatia esquerda necropsia brancoamarelada branco amarelada enegrecidas irregular granular friável coanas frontais cérebro notouse notou epitélios celulares secundária SNC (SNC vasos imunohistoquímica. imunohistoquímica imuno histoquímica. histoquímica imuno-histoquímica

ABSTRACT There is great interest in varieties with greater competitive ability against weeds. This can be facilitated by path analysis, which involves the statistical evaluation and interpretation of the relationship between yield and its components. In this analysis, the occurrence of multicollinearity results in inconsistent estimates of the coefficients, and overestimates of the direct effects of the explanatory variables on the response variable. The aim of this study was to identify the characteristics with the greatest direct effect on pod yield and green and dry bean yields in traditional cowpea varieties, evaluated in competition with weeds in two experiments. In addition, the presence of multicollinearity was investigated in the analyses. In Experiment-1, twelve varieties with the highest bean yields in a preliminary evaluation were assessed in a randomized block design with five replications. In Experiment-2, six varieties, selected in the preliminary evaluation, were assessed using two methods of weed management: three of the most productive and three of the least productive. Randomized blocks and split plots were used, with five replications. Multicollinearity, indicated by the number of conditions and the variance inflation values, was greater in Experiment-2. In the six cases under study (three yields x two experiments), the number of pods per plant had the greatest direct effect on yield. analysis components coefficients variable experiments addition analyses Experiment1, Experiment1 Experiment 1, 1 Experiment-1 replications Experiment2, Experiment2 2, 2 Experiment-2 management used Multicollinearity values Experiment2. 2. experiments, , experiments) Experiment-

ABSTRACT The aim of this study was to identify drought-tolerant parents and combinations of common bean based on general and specific combining abilities. A complete diallel was conducted, including the reciprocals, among 12 parents, obtaining 132 populations. These populations and respective parents were evaluated in pots in a greenhouse in a randomized block experimental design with three replications and placed under intermittent water deficit applied in the pre-flowering. Physiological, morphological, and agronomic traits were evaluated, and general combining ability (GCA), specific combining ability (SCA), and reciprocal effect (RE) were estimated. Significant effects were found among the genotypes for most of the traits confirming genetic variability among populations. The additive effects were more expressive than the non-additive effects, with reciprocal effect for some traits. The Carioca Precoce and SER 16 parents exhibited significant GCA, contributing alleles favorable to additive effects for increasing grain yield and harvest index. Significance of SCA and RE was not observed for grain yield. However, the SEA 5 (pollen receptor) × SER 16, Carioca Precoce (pollen receptor) × BRS FP403, and the reciprocal Carioca Precoce (pollen donor) × BRS FP403 hybrid combinations achieved positive estimates for harvest index, which is an indirect selection trait for grain yield. This study allowed selection of progenies coming from the parents Carioca Precoce and SER 16, as manifested favorable traits related to grain yield. droughttolerant drought tolerant abilities conducted reciprocals 1 13 preflowering. preflowering pre flowering. flowering pre-flowering Physiological morphological GCA , (GCA) SCA, (SCA) (RE estimated nonadditive non index However pollen receptor FP donor FP40 (GCA (SCA FP4

ABSTRACT The Tunicata, despite the relatively low species diversity among the invertebrates, has always received attention not only due to their ecological importance, especially in fouling communities, but also for several species that are studied as models for genetics and the evolution of development, as well as being a prolific source of natural products. In Brazil, research during the last 60 years has considerably increased our knowledge of benthic and planktonic tunicates, resulting from the work of several research teams. In this review, we provide information on the biodiversity of coastal Brazil along with an analysis of geographic distribution, sampling effort, the locations and status of taxonomic collections, and research specialists working on this group. Tunicata invertebrates importance communities development products 6 tunicates teams review distribution effort collections group

Abstract Cardiac tumors are rare entities, among which atrial myxoma (AM) stands as the most frequent, accounting for approximately half of all reported cases. The incidence of AM is estimated to range from 0.001% to 0.3% within the general population, yet only about 0.06% of these cases present with coronary embolic events. We report on a 33-year-old male smoker who experienced acute, severe precordial pain radiating to the left upper limb, lasting for one hour. The electrocardiographic evaluation demonstrated ST-segment elevation in leads D2, D3, and aVF, alongside significantly elevated serum troponin levels, confirming a diagnosis of ST-segment elevation myocardial infarction (STEMI). Subsequent coronary angiography revealed proximal occlusion of the right coronary artery due to thrombus. An initial attempt of thrombus aspiration was unsuccessful, followed by primary angioplasty with balloon inflation without stent placement. Further diagnostic exploration through transthoracic echocardiography identified a homogenous, smooth-surfaced mass measuring 5.2 cm x 2.3 cm attached to the interatrial septum. This mass, characterized by lobulations, prolapsed into the mitral valve and left ventricle during diastole, consistent with AM. Surgical resection of the mass was successfully performed, with the patient being discharged asymptomatic. In the reported case, the patient's profile, notably his age, and gender, diverges from the typical epidemiological characteristics associated with AM. This case adds to the limited number of reports where the inferior wall is affected by the right coronary artery being occluded. This report emphasizes the significance of differential diagnoses in younger patients presenting with STEMI. entities (AM frequent 0001 0 001 0.001 03 3 0.3 population 006 06 0.06 events 33yearold yearold 33 year old acute limb hour STsegment ST segment D2 D D3 aVF levels STEMI . (STEMI) unsuccessful placement homogenous smoothsurfaced smooth surfaced 52 5 2 5. 23 2. septum lobulations diastole performed asymptomatic s profile age gender occluded 000 00 0.00 0. 0.0 (STEMI

Resumo Neoplasias cardíacas são raras, tendo como principal representante o mixoma atrial (MA), que corresponde a cerca de metade de todos os casos. O MA tem incidência estimada entre 0.001% e 0.3% na população em geral, no entanto apenas aproximadamente 0,06% desses cursam com eventos embólicos coronarianos. Homem de 33 anos, tabagista, admitido com quadro de precordialgia intensa e irradiação para membro superior esquerdo com duração de uma hora. O eletrocardiograma evidenciou elevação de segmento ST nas derivações D2, D3 e aVF troponina sérica elevada, confirmando infarto com supra desnivelamento do segmento ST (IAMCSST). Foi realizada cineangiocoronariografia, a qual revelou oclusão em terço proximal de artéria coronária direita por trombo. Realizada tentativa de aspiração do trombo, sem sucesso, seguido por angioplastia primária com balão sem colocação de stent. Durante a investigação do quadro, paciente realizou ecocardiograma transtorácico o qual demonstrou massa homogênea de superfície regular, de 5.2 cm x 2.3 cm, aderida ao septo interatrial, com lobulações de características emboligênicas prolapsando para valva mitral e ventrículo esquerdo na diástole, compatível com MA. Foi realizada ressecção cirúrgica com paciente evoluindo assintomático, recebendo alta para seguimento ambulatorial. O caso relatado difere em idade e sexo do perfil epidemiológico típico sendo um dos poucos descritos com acometimento da parede inferior apresentando a artéria coronária direita como culpada. Este relato ratifica a importância do diagnóstico diferencial frente às apresentações de IAMCSST em jovens. raras MA, , (MA) casos 0001 0 001 0.001 03 3 0.3 geral 006 06 0,06 coronarianos anos tabagista hora D2 D elevada IAMCSST. . (IAMCSST) cineangiocoronariografia trombo sucesso stent regular 52 5 2 5. 23 2. interatrial diástole assintomático ambulatorial culpada jovens (MA 000 00 0.00 0. 0,0 (IAMCSST 0.0 0,

Abstract Introduction Onodi cells (OCs) are posterior ethmoid cells that are located above the sphenoid sinus, close to or even surrounding the carotid artery and optic nerve. Objective To investigate and evaluate the volumetric variation of OCs through multi-slice computed tomography (MSCT) scans. Methods We performed a retrospective review of MSCT scans of 79 subjects, 40 male and 39 female patients, Whose age ranged from 18 to 83 (mean: 39.6) years. The volumes of the OCs on the right and left sides were measured using the ITK-SNAP software (open-source) with semiautomatic segmentation. The possible relationships involving age, gender, contact with the optic nerve, extension of the pneumatization of the posterior ethmoid cells into the clinoid processes, mucous thickening in the anterior and posterior ethmoid cells, and obliteration of the sphenoethmoidal complex were analyzed with the Pearson correlation and Chi-squared tests according to the type of data compared and logistic regression models (p < 0.05). Results We observed that an increase of one unit in the volume of OCs also increases the chance of extension of pneumatization into the clinoid processes by 0.15% (p = 0.001). No significant correlations were identified regarding age, gender, and volume of the OCs. Conclusion The volume of the OCs has effects on the extension of pneumatization into the clinoid processes. (OCs sinus nerve multislice multi slice (MSCT 7 subjects 4 3 patients 1 8 mean (mean 39.6 396 6 years ITKSNAP ITK SNAP opensource open source (open-source segmentation gender Chisquared Chi squared p 0.05. 005 0.05 . 0 05 0.05) 015 15 0.15 0.001. 0001 0.001 001 0.001) 39. 00 0.0 01 0.1 000 0.00 0.

Resumo Objetivo Este estudo tem como objetivo analisar a relação entre a compensação executiva e o prestigio corporativo baseado na literatura. Metodologia Organizamos e analisamos sistematicamente periódicos revisados por pares de 1960 a 2021 para avaliar a progressão acadêmica em remuneração de executivos e prestígio corporativo. Analisamos 59 artigos da Web of Science Core Collection e do banco de dados Scopus. Resultados Identificamos um aumento na taxa de publicações por ano sobre esse tópico. A síntese da literatura revela que, fundamentalmente, os estudos foram realizados nos Estados Unidos. Os resultados também mostram que há pouca relação entre os pesquisadores e, por fim, identificamos uma lacuna na literatura, pois a maioria dos estudos sobre remuneração de executivos não considera o prestígio corporativo, o desempenho e a remuneração em conjunto. Originalidade/valor Este estudo é pioneiro na realização de uma revisão sistemática da literatura que considera a interconexão entre remuneração e prestígio. As contribuições deste estudo consistem em identificar e sistematizar o conhecimento e derivar a lacuna de pesquisa e pesquisas futuras, o que é útil para acadêmicos e profissionais entenderem a remuneração de executivos e o prestígio corporativo, pois os dados revelam um campo de estudo a ser considerado e analisado. 196 202 5 Scopus tópico fundamentalmente Unidos fim conjunto Originalidadevalor Originalidade valor futuras analisado 19 20 1 2

Abstract Purpose This study aims to analyze the relationship between executive compensation and corporate prestige based on scientific literature. Methodology We systematically organized and analyzed peer-reviewed journals from 1960 to 2021 to assess the academic progression in executive compensation and corporate prestige. We analyzed 59 articles from the Web of Science Core Collection and Scopus databases. Findings We identified an increase in the rate of publications per year on this topic. The synthesis of the literature reveals that, fundamentally, the United States carried out the studies. Results also show that there is little relationship between researchers, and, finally, we identified a gap in the literature as most studies on executive compensation do not consider corporate prestige, performance, and compensation together. Originality/Value This study is a pioneer in undertaking a systematic literature review considering the interconnection between compensation and prestige. The contributions of this study consist of identifying and systematizing knowledge and deriving the research gap and future research, which is helpful for academics and practitioners to understand executive compensation and corporate prestige as the data reveal a field of study to be considered and analyzed. peerreviewed peer reviewed 196 202 5 databases topic fundamentally researchers finally performance together OriginalityValue Originality Value 19 20 1 2

Abstract: This paper presents an overview of the themes and contents covered in Astronomy Education Research conducted in postgraduate programs in Brazil between 1973 and 2018. The researchers used Content Analysis to deal with 490 studies and identify the most discussed themes and their correlation with different stages of education, including Basic Education, Higher Education, and Non-School Education. The results showed that the Sun-Earth-Moon system is the most discussed theme in Elementary and Secondary Education, while Celestial Mechanics and gravity are more prevalent in Higher Education. Research on Non-School Education often does not focus on specific themes. The researchers discovered a central focus on teaching and learning processes, reflected in the emphasis on content and method. The study identifies trends and gaps that can contribute to developments in this field. Abstract 197 2018 49 education NonSchool Non School SunEarthMoon Sun Earth Moon processes method field 19 201 4 1 20 2

Resumo: Esta pesquisa, do tipo Estado da Arte, apresenta um recorte sobre temas e conteúdos abordados nos estudos sobre Educação em Astronomia produzidos em cursos de pós-graduação no Brasil, de 1973 a 2018. Foram recuperados e analisados 490 estudos, por meio da ferramenta metodológica Análise de Conteúdo. Identificados os mais abordados, correlaciona-se a abordagem com as diferentes etapas da Educação Básica, com o Ensino Superior e com a Educação Não Escolar. O Sistema Sol-Terra-Lua destaca-se no Ensino Fundamental e Médio, enquanto no Ensino Superior, observa-se a predominância de estudos em Mecânica Celeste e Gravitação. As pesquisas na Educação Não Escolar, em geral, não se dedicam a temas específicos. A correlação entre Temas e Conteúdos e o Foco Temático têm ênfase em Conteúdo e Método, refletindo atenção central nos processos de ensino e aprendizagem. Desse modo, indica-se tendências e lacunas com o propósito de contribuir com o desenvolvimento da área. Resumo pesquisa Arte pósgraduação pós graduação Brasil 197 2018 49 correlacionase correlaciona Básica Escolar SolTerraLua Sol Terra Lua destacase destaca Médio observase observa Gravitação geral específicos Método aprendizagem modo indicase indica área 19 201 4 1 20 2

Biocomposites have gained attention in the packaging industry due to their potential as sustainable alternatives to conventional synthetic materials. In this study, novel cotton incorporated poly(lactic acid)/thermoplastic starch biocomposites were developed for packaging applications using in short shelf life products the extrusion method. Pelletized samples obtained by extrusion were stamped from plates obtained by compression and were characterized through measurement of density, hardness, contact angle and water absorption, as well as Fourier transform infrared spectroscopy (FTIR), thermal analysis and scanning electron microscopy (SEM). No significant changes in the density results were observed. A slight increase in the hardness of formulations in relation to the PLA was associated with the presence of cotton fiber in biocomposites. The FTIR results revealed physical interaction of PLA, TPS and cotton fiber. By DSC analysis, for all formulations the melting exhibited only one peak, suggesting good homogeneity and interaction among the components, as observed by TG/DTG results, and corroborating SEM analysis. The biocomposite PLA/TPS/Cotton 85/10/5 wt.% displayed greater increase in water absorption than both 95/5/0 and 90/5/5 wt.% formulations, which can be attributed to the increase in starch proportion, confirming the contact angle results. The hydrophilic tendency corroborated the biodegradation process in the packaging end-of-life. materials study polylactic poly lactic acid/thermoplastic acidthermoplastic acid /thermoplastic thermoplastic method FTIR, , (FTIR) SEM. . (SEM) peak components TGDTG TG DTG PLATPSCotton Cotton 85105 85 10 5 85/10/ wt wt. 9550 95 0 95/5/ 9055 90 90/5/ proportion endoflife. endoflife end life. end-of-life (FTIR (SEM 8510 8 1 85/10 955 9 95/5 905 90/5 851 85/1 95/ 90/ 85/

ABSTRACT Biological soil crusts (BSC) are commonly found in soils in the drylands regions, which can influence stabilization, water retention, nutrient cycling (particularly carbon (C) and nitrogen (N) dynamics), and several ecological processes. However, the composition of BSC in Brazilian soils undergoing the desertification process remains poorly understood. This study aimed to characterize the bacterial community in BSC formed in a Brazilian semiarid region under the desertification process. Thus, a highly desertified region was selected from which 34 BSC samples were collected. The total DNA of the BSC was extracted from 0.5 g samples, and the bacterial community was sequenced by a Next Generation Sequencing (NGS) platform (Miseq – Illumina®) using universal primers (515F and 806R). Bioinformatic analysis was carried out in QIIME (v.1.9), and the Operational Taxonomic Units (OTU) table was constructed following the Sumaclust methodology. The pH of BSC, C, N, and phosphorus contents was analyzed. Our study identified a diverse bacterial community in the BSCs. Cyanobacteria, Chloroflexi, and Proteobacteria phyla presented the greatest relative abundance (%) across the samples. Cyanobacteria were dominated by the orders Nostocales and Leptolyngbyales. The prediction of the putative functions found that mostf OTU were related to phototrophy, photosynthetic cyanobacteria, and photoautotrophy. The study found correlations between bacterial phyla and BSC properties, with Cyanobacteria positively related to C. Chloroflexi, Armatimonadetes, and WPS-2 were negatively correlated with C and N contents. These results suggest the critical roles bacteria communities play in BSCs from the Caatinga biome and highlight the potential impact of environmental factors on their diversity and functions. (BSC regions stabilization retention particularly (C (N dynamics, dynamics , dynamics) processes However understood Thus 3 collected 05 0 5 0. NGS (NGS Miseq Illumina® Illumina 515F F 806R. 806R R . 806R) v.1.9, v19 v v.1.9 1 9 (v.1.9) (OTU methodology analyzed Chloroflexi % (% Leptolyngbyales phototrophy cyanobacteria photoautotrophy properties Armatimonadetes WPS2 WPS 2 WPS- v1 v.1. (v.1.9 ( v.1 (v.1. v. (v.1 (v. (v

ABSTRACT The continuous demand for water in the agricultural sector has encouraged researchers worldwide to find alternatives to optimize this resource. The use of wastewater in irrigation is promising in this scenario, especially to produce tree seedlings. The growth, quality, and water productivity of Dalbergia nigra seedlings cultivated with sewage sludge were determined when irrigated with urban supply water (W1) and cattle wastewater (CWW) treated for 1 h (W2) and 2 h (W3) of ozonation, considering four irrigation depths and shading levels (0 % (C1), 37.6 % (C2), 49.4 % (C3), 75.8 % (C4)). The height, stem diameter, biomass, and the Dickson Quality Index (DQI) were evaluated. The largest volumes of water applied in each experiment were 2.342 L per plant in W2C1, 2.114 L per plant in W1C3 and 1.556 L per plant in W3C1. The CWW provided satisfactory seedling growth, especially W2, highlighting a DQI of 0.47 obtained in C1 and better water productivity (3.8 g L–1) in W2C1, with full depth. Using alternative inputs in the seedling production of tree species is a promising strategy and indicates benefits for waste disposal, such as sewage sludge and wastewater. resource scenario growth quality W1 W (W1 (CWW W2 (W2 W3 (W3 ozonation 0 ( C1, C , (C1) 376 37 6 37. C2, C2 (C2) 494 49 4 49. C3, C3 (C3) 758 75 8 75. C4. C4 . (C4)) height diameter biomass (DQI evaluated 2342 342 2.34 W2C1 WC 2114 114 2.11 W1C 1556 556 1.55 W3C1 047 47 0.4 3.8 38 3 (3. L–1 L1 depth disposal (W (C1 (C2 (C3 7 (C4) 234 34 2.3 W2C 211 11 2.1 155 55 1.5 W3C 04 0. 3. (3 L– (C (C4 23 2. 21 15 5 1.

Abstract Background: In this experimental protocol, we evaluated the immediate and delayed repair of the buccal branch of the facial nerve (BBFN) with heterologous fibrin biopolymer (HFB) as a coaptation medium and the use of photobiomodulation (PBM), performing functional and histomorphometric analysis of the BBFN and perioral muscles. Methods: Twenty-eight rats were divided into eight groups using the BBFN bilaterally (the left nerve was used for PBM), namely: G1 - control group, right BBFN (without injury); G2 - control group, left BBFN (without injury + PBM); G3 - Denervated right BBFN (neurotmesis); G4 - Denervated left BBFN (neurotmesis + PBM); G5 - Immediate repair of right BBFN (neurotmesis + HFB); G6 - Immediate repair of left BBFN (neurotmesis + HFB + PBM); G7 - Delayed repair of right BBFN (neurotmesis + HFB); G8 - Delayed repair of left BBFN (neurotmesis + HFB + PBM). Delayed repair occurred after two weeks of denervation. All animals were sacrificed after six weeks postoperatively. Results: In the parameters of the BBFN, we observed inferior results in the groups with delayed repair, in relation to the groups with immediate repair, with a significant difference (p < 0.05) in the diameter of the nerve fiber, the axon, and the thickness of the myelin sheath of the group with immediate repair with PBM compared to the other experimental groups. In measuring the muscle fiber area, groups G7 (826.4 ± 69.90) and G8 (836.7 ± 96.44) were similar to G5 (882.8 ± 70.51). In the functional analysis, the G7 (4.10 ± 0.07) and G8 (4.12 ± 0.08) groups presented normal parameters. Conclusion: We demonstrated that delayed repair of BBFN is possible with HFB, but with worse results compared to immediate repair, and that PBM has a positive influence on nerve regeneration results in immediate repair. Background protocol (BBFN (HFB PBM, , (PBM) muscles Methods Twentyeight Twenty PBM) namely G without injury) neurotmesis (neurotmesis) HFB) PBM. . denervation postoperatively Results p 0.05 005 0 05 axon area 826.4 8264 826 4 (826. 69.90 6990 69 90 836.7 8367 836 7 (836. 96.44 9644 96 44 882.8 8828 882 8 (882. 70.51. 7051 70.51 70 51 70.51) 4.10 410 10 (4.1 0.07 007 07 4.12 412 12 0.08 008 08 Conclusion (PBM 0.0 00 826. 82 (826 69.9 699 6 9 836. 83 (836 96.4 964 882. 88 (882 705 70.5 5 4.1 41 1 (4. 0. (82 69. (83 96. (88 70. 4. (4 (8 (

ABSTRACT With the objective of evaluate the use of residues as growing media for the yellow passion fruit seedlings, a randomized block experiment was carried out with treatments distributed in a 2 × 21 factorial scheme corresponding to fertilizer management (presence and absence of controlled-release fertilizer), and combination of growing media from five local agro-industrial wastes (bark of cupuaçu fruit, almond shell of castanha-do-brasil, lumps of acerola fruit, lumps of cajá fruit, and lumps of açaí fruit) and a commercial growing media, which tested pure and was combined in a 1:1 ratio. The variables measured were the seedling height; stem diameter; height: stem diameter ratio; number of leaves; shoot, root, and total dry matter; and Dickson quality index. The dates were submitted to univariate and multivariate analyzes. The pairwise combination of growing medias produced from the bark of cupuaçu fruit, almond shell of castanha-do-brasil, lumps of acerola fruit, lumps of cajá fruit, lumps of açaí fruit, and commercial growing media in a proportion of 1:1 and with the use of controlled-release fertilizer constitute an alternative for other growing medias in the production of yellow passion fruit seedlings. seedlings presence controlledrelease controlled release fertilizer, , fertilizer) agroindustrial agro industrial castanhadobrasil, castanhadobrasil castanha do brasil, brasil castanha-do-brasil 11 1 1: ratio height leaves shoot root matter index analyzes

Abstract We predicted miRNAs with regulatory impact on NFKB1 and TRAF6 gene expression and selected the miR-194-5p, miR-124-3p, miR-9-5p, and miR-340-5p and their target genes for expression analyses on CD14+ monocytes from rheumatoid arthritis (RA) patients and healthy controls. Additionally, we evaluated the influence of genes and miRNA expression on RA patients’ cytokine levels. No difference was observed in genes or miRNAs expression when compared to healthy controls and RA patients or clinical parameters. However, we found a significant difference between miR-194-5p and miR-9-5p levels (FC=-2.31; p=0.031; FC=-3.05;p=0.031, respectively) and non-prednisone users as compared to prednisone using patients. We conducted correlation analyses to identify the strength of the relationship between expression data and cytokine plasma levels. We observed a moderate positive correlation between miR-124-3p expression and IL-6 plasma levels (r=0.46; p=0.033). In addition, overexpression of miRNAs was concomitant to TRAF6 and NFKB1 genes as indicated by correlation analyses: TRAF6 and miR-194-5p (r=0.60;p<0.001) and miR-9-5p (r=0.63;p<0.001) and NFKB1 and miR-194-5p (r=0.72;p<0.001), miR-9-5p (r=0.72;p<0.001) and miR-340-5p (r=0.61;p<0.001). NFKB1 and TRAF6 genes and miRNAs monocyte expression do not appear to be related to RA but showed a significant difference in different groups of RA therapy. In addition, increased levels of miRNAs can be linked to concomitant overexpression of TRAF6 and NFKB1 in monocytes and act as its regulators. NFKB TRAF miR1945p, miR1945p miRp miR 194 5p, 5p p miR1243p, miR1243p 124 3p, 3p miR95p, miR95p 9 miR3405p 340 CD14 CD (RA Additionally parameters However FC=2.31 FC231 FC FC= 2.31 2 31 (FC=-2.31 p=0.031 p0031 0 031 FC=3.05p=0.031, FC305p0031 FCp 3.05 p=0.031, 3 05 FC=-3.05;p=0.031 respectively nonprednisone non IL6 IL 6 IL- r=0.46 r046 r 46 (r=0.46 p=0.033. p0033 p=0.033 . 033 p=0.033) addition r=0.60p<0.001 r060p0001 rp r=0.60 p<0.001 60 001 (r=0.60;p<0.001 r=0.63p<0.001 r063p0001 r=0.63 63 (r=0.63;p<0.001 r=0.72p<0.001, r072p0001 r=0.72 , 72 r=0.72p<0.001 (r=0.72;p<0.001 r=0.61p<0.001. r061p0001 r=0.61 61 (r=0.61;p<0.001) therapy regulators 19 12 34 CD1 FC=2.3 FC23 231 2.3 (FC=-2.3 p=0.03 p003 03 05p FC=3.05p=0.031 FC305p003 305 3.0 FC=-3.05;p=0.03 r=0.4 r04 4 (r=0.4 60p r=0.60p<0.00 r060p000 r060 r=0.6 p0001 p<0.00 00 (r=0.60;p<0.00 63p r=0.63p<0.00 r063p000 r063 (r=0.63;p<0.00 72p r072p000 r072 r=0.7 7 r=0.72p<0.00 (r=0.72;p<0.00 61p r=0.61p<0.001 r061p000 r061 (r=0.61;p<0.001 1 FC=2. FC2 23 2. (FC=-2. p=0.0 p00 FC=3.05p=0.03 FC305p00 30 3. FC=-3.05;p=0.0 r=0. r0 (r=0. r=0.60p<0.0 r060p00 r06 p000 p<0.0 (r=0.60;p<0.0 r=0.63p<0.0 r063p00 (r=0.63;p<0.0 r072p00 r07 r=0.72p<0.0 (r=0.72;p<0.0 r=0.61p<0.00 r061p00 (r=0.61;p<0.00 FC=2 (FC=-2 p=0. p0 FC=3.05p=0.0 FC305p0 FC=-3.05;p=0. r=0 (r=0 r=0.60p<0. r060p0 p<0. (r=0.60;p<0. r=0.63p<0. r063p0 (r=0.63;p<0. r072p0 r=0.72p<0. (r=0.72;p<0. r=0.61p<0.0 r061p0 (r=0.61;p<0.0 (FC=- p=0 FC=3.05p=0. FC305p FC=-3.05;p=0 r= (r= r=0.60p<0 r060p p<0 (r=0.60;p<0 r=0.63p<0 r063p (r=0.63;p<0 r072p r=0.72p<0 (r=0.72;p<0 r=0.61p<0. r061p (r=0.61;p<0. (FC= p= FC=3.05p=0 FC=-3.05;p= (r r=0.60p< p< (r=0.60;p< r=0.63p< (r=0.63;p< r=0.72p< (r=0.72;p< r=0.61p<0 (r=0.61;p<0 (FC FC=3.05p= FC=-3.05;p r=0.60p (r=0.60;p r=0.63p (r=0.63;p r=0.72p (r=0.72;p r=0.61p< (r=0.61;p< FC=3.05p r=0.61p (r=0.61;p

Resumen Este estudio buscó evaluar la satisfacción y la sobrecarga de los profesionales de la salud mental en un municipio de tamaño medio de São Paulo (Brasil). Fue realizado un estudio cuantitativo y cualitativo, utilizando la Escala de Evaluación de la Satisfacción de los Profesionales de los Servicios de Salud Mental y la Escala de Evaluación de la Sobrecarga de los Profesionales de los Servicios de Salud Mental para los datos cuantitativos. Además, se obtuvieron datos cualitativos mediante el análisis de las minutas de las reuniones del Comité Directivo de Investigación con el apoyo del software NVivo Release 1.3. Los resultados obtenidos señalaron que los profesionales de la salud mental presentaban una menor sobrecarga en los servicios de su área, pero estaban insatisfechos con su trabajo. A pesar de que la satisfacción fue relativamente mayor en los Centros de Atención Psicosocial de Alcohol y Drogas y en los Centros de Atención Psicosocial II en comparación con el ambulatorio, estas diferencias no fueron estadísticamente significativas. En resumen, los resultados indican que una mayor insatisfacción y una menor sobrecarga no son hechos independientes y coinciden con otros estudios. La triangulación de las fuentes de datos ha contribuido a una comprensión mayor del tema, destacando la importancia de considerar la satisfacción y la sobrecarga de los profesionales en la mejora de la atención a la salud mental. Brasil. Brasil . (Brasil) cualitativo cuantitativos Además 13 1 3 1.3 área trabajo ambulatorio significativas resumen estudios tema (Brasil 1.

Abstract This study aimed to evaluate the satisfaction and burden of mental health professionals in a medium-sized municipality in São Paulo, Brazil. A quantitative-qualitative study was conducted using the Mental Health Services Professional Satisfaction Rating Scale and the Mental Health Services Professional Burden Rating Scale for quantitative data. In addition, qualitative data were obtained through the analysis of minutes of the Research Steering Committee meetings with the support of the NVivo Release 1.3 software. The results revealed that mental health professionals experienced less overload in services in their area but were dissatisfied with their work. Although satisfaction was relatively higher in the Alcohol and Drugs Psychosocial Care Centers and Psychosocial Care Centers II compared to the outpatient clinic, these differences were not statistically significant. In short, the findings indicate that greater dissatisfaction and less overload are not independent events and corroborate other studies. The triangulation of data sources contributed to a broader understanding of the topic, highlighting the importance of considering the satisfaction and burden of professionals in improving mental health care. mediumsized medium sized Paulo Brazil quantitativequalitative addition 13 1 3 1. software work clinic significant short studies topic care

Resumo Buscou-se neste estudo avaliar a satisfação e a sobrecarga de profissionais de saúde mental em um município de médio porte em São Paulo. Realizou-se um estudo quantiqualitativo, com a Escala de Avaliação da Satisfação de Profissionais em Serviços de Saúde Mental e a Escala de Avaliação da Sobrecarga de Profissionais em Serviços de Saúde Mental para dados quantitativos. Além disso, dados qualitativos foram obtidos por meio da análise de atas das reuniões do Comitê Gestor da Pesquisa com o suporte do software NVivo Release 1.3. Os resultados revelaram que os profissionais de saúde mental experimentaram menor sobrecarga nos serviços de sua área, porém mostraram-se insatisfeitos com o trabalho. Embora a satisfação tenha sido relativamente mais alta nos Centros de Atenção Psicossocial Álcool e Drogas e nos Centros de Atenção Psicossocial II em comparação com o ambulatório, essas diferenças não foram estatisticamente significativas. Em suma, os achados indicam que maior insatisfação e menor sobrecarga não são eventos independentes e corroboram outros estudos. A triangulação de fontes de dados contribuiu para uma compreensão mais ampla do tema, destacando-se a importância de se considerarem a satisfação e a sobrecarga dos profissionais na melhoria do cuidado em saúde mental. Buscouse Buscou Paulo Realizouse Realizou quantiqualitativo quantitativos disso 13 1 3 1.3 área mostraramse mostraram trabalho ambulatório significativas suma estudos tema destacandose destacando 1.