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Safety of two-dose schedule of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan) and heterologous additional doses of mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised and immunocompetent individuals
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Miyaji, Karina Takesaki

; Ibrahim, Karim Yaqub

; Infante, Vanessa

; Moreira, Raquel Megale

; Santos, Carolina Ferreira dos Belizário, Juliana de Cássia Pinto, Maria Isabel de Moraes Marinho, Ana Karolina Barreto Berselli Pereira, Juliana Marquezi Mello, Liliane Saraiva de Silva, Vitor Gabriel Lopes da Sato, Paula Keiko Strabelli, Tânia Mara Varejão Ragiotto, Lucas Pacheco, Pedro Henrique Theotonio de Mesquita Braga, Patricia Emilia Loch, Ana Paula Precioso, Alexander Roberto Sartori, Ana Marli Christovam França, João Ítalo Lima, Marcos Alves de Ando, Mauricio Cesar Sampaio Rodrigues, Camila Cristina Martini Song, Alice Tung Wan Lara, Amanda Nazareth Belizário, Ana Cristina Lima, Anna Helena Simões Bortulucci de Zanetti, Ariane Cristina Barboza Paulo, Audrey Rose da Silveira Amancio de Rosa, Barbara Miranda dos Santos Moraes, Bruna Del Guerra de Carvalho Oliveira, Bruna Ribeiro de Picone, Camila de Melo Aranda, Carolina Sanches Troli, Carolinne Paioli Kokron, Cristina M. Terrabuio, Debora Raquel Benedita Abdala, Edson David Neto, Elias Nakanishi, Érika Yoshie Shimoda Lima, Fabiana Mascarenhas Souza Firmino, Fabio Batista Santos, Fernanda Barone Alves dos Bacal, Fernando Fatobene, Giancarlo Santana, Jaqueline Oliveira Kalil, Jorge Barbosa, Julia Gonçalves, Leandro Peres Otuyama, Leonardo Jun Pierrotti, Ligia Camera Compte, Livia Caroline Mariano Marinho, Livia Chaer, Livia Netto Seguro, Luis Fernando Azevedo, Luiz Sergio Ueda, Márcia Aiko Terreri, Maria Teresa Barros, Myrthes Anna Maragna Toledo Grecco, Octávio Sejas, Odeli Nicole Encinas Musqueira, Priscila Tavares Ito, Raquel Keiko de Luca Teixeira, Samia Silveira Souza Fidalgo, Serafim Costa, Silvia Figueiredo Campos, Silvia Vidal Fernandes, Tamiris Hinsching Rocha, Vanderson Geraldo Coelho, Vivian Caso

Revista do Instituto de Medicina Tropical de São Paulo

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2025, Volume 67 elocation e2

Resumo: En | Texto: En | PDF: En

ABSTRACT Immunocompromised individuals were considered high-risk for severe disease due to SARS COV-2 infection. This study aimed to describe the safety of two doses of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan), followed by additional doses of mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised (IC) adults, compared to immunocompetent/healthy (H) individuals. This phase 4, multicenter, open label study included solid organ transplant and hematopoietic stem cell transplant recipients, cancer patients and people with inborn errors of immunity with defects in antibody production, rheumatic, end-stage chronic kidney or liver disease, who were enrolled in the IC group. Participants received two doses of CoronaVac and additional doses of mRNA BNT162b2. Adverse reactions (AR) data were collected within seven days after each vaccination. Serious adverse events and of special interest (AESI) were monitored throughout the study. We included 241 immunocompromised and 100 immunocompetent subjects. Arthralgia, fatigue, myalgia, and nausea were more frequent in the IC group after CoronaVac. Following the first additional dose of mRNA BNT162, pain, induration, and tenderness at injection site, fatigue and myalgia were more frequent in the H group. A heart transplant recipient had a graft rejection temporally associated with the second CoronaVac dose, but there was no literature evidence of causal association. Four cases of AESI were considered related to the vaccine: three erythema multiforme after CoronaVac, all in IC participants, and one paresthesia after mRNA, in a H participant. Our findings were comparable to other studies that evaluated the safety of COVID-19 vaccines in different immunocompromised populations. Both vaccines were safe for immunocompromised participants.

https://doi.org/10.1590/s1678-9946202567002

Immunogenicity of COVID-19 adsorbed inactivated vaccine (CoronaVac) and additional doses of mRNA BNT162b2 vaccine in immunocompromised adults compared with immunocompetent persons COVID19 COVID 19 COVID-1 CoronaVac (CoronaVac BNTb BNT b BNT162b COVID1 1 COVID-
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Ibrahim, Karim Yaqub

; Moreira, Raquel Megale

; Santos, Carolina Ferreira dos

; Strabelli, Tânia Mara Varejão

; Belizário, Juliana de Cássia

; Pinto, Maria Isabel de Moraes

; Marinho, Ana Karolina Barreto Berselli

; Pereira, Juliana Marquezi

; Mello, Liliane Saraiva de

; Ando, Mauricio Cesar

; Silva, Vitor Gabriel Lopes da

; Sato, Paula Keiko

; Lima, Marcos Alves de

; França, João Italo Dias

; Loch, Ana Paula

; Miyaji, Karina Takesaki

; Infante, Vanessa

; Precioso, Alexander Roberto

; Sartori, Ana Marli Christovam

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e24

Resumo: En | Texto: En | PDF: En

ABSTRACT Inactivated COVID-19 vaccines data in immunocompromised individuals are scarce. This trial assessed the immunogenicity of two CoronaVac doses and additional BNT162b2 mRNA vaccine doses in immunocompromised (IC) and immunocompetent (H) individuals. Adults with solid organ transplant (SOT), hematopoietic stem cell transplant, cancer, inborn immunity errors or rheumatic diseases were included in the IC group. Immunocompetent adults were used as control group for comparison. Participants received two CoronaVac doses within a 28-day interval. IC received two additional BNT162b2 doses and H received a third BNT162b2 dose (booster). Blood samples were collected at baseline, 28 days after each dose, pre-booster and at the trial end. We used three serological tests to detect antibodies to SARS-CoV-2 nucleocapsid (N), trimeric spike (S), and receptor binding domain (RBD). Outcomes included seroconversion rates (SCR), geometric mean titers (GMT) and GMT ratio (GMTR). A total of 241 IC and 100 H adults participated in the study. After two CoronaVac doses, IC had lower SCR than H: anti-N, 33.3% vs 79%; anti-S, 33.8% vs 86%, and anti-RBD, 48.5% vs 85%, respectively. IC also showed lower GMT than H: anti-N, 2.3 vs 15.1; anti-S, 58.8 vs 213.2 BAU/mL; and anti-RBD, 22.4 vs 168.0 U/mL, respectively. After the 3rd and 4th BNT162b2 doses, IC had significant anti-S and anti-RBD seroconversion, but still lower than H after the 3rd dose. After boosting, GMT increased in IC, but remained lower than in the H group. CoronaVac two-dose schedule immunogenicity was lower in IC than in H. BNT162b2 heterologous booster enhanced immune response in both groups. COVID19 COVID 19 COVID-1 scarce BNTb BNT b BNT162b (IC (H SOT, SOT , (SOT) cancer comparison 28day day interval booster. . (booster) baseline 2 prebooster pre end SARSCoV2 SARSCoV SARS CoV SARS-CoV- N, N (N) S, S (S) RBD. RBD (RBD) SCR, (SCR) (GMT GMTR. GMTR (GMTR) 24 10 study antiN, antiN anti anti-N 333 33 3 33.3 79% 79 antiS, antiS 338 8 33.8 86 86% antiRBD, antiRBD RBD, 485 48 5 48.5 85 85% respectively 23 2. 15.1 151 15 1 588 58 58. 2132 213 213. BAU/mL BAUmL BAU mL 224 22 4 22. 1680 168 0 168. UmL U U/mL rd th boosting twodose groups COVID1 COVID- (SOT (booster SARS-CoV (N (S (RBD (SCR (GMTR 33. 7 48. 15. 21 16

https://doi.org/10.1590/s1678-9946202466024

Factors associated with oropharyngeal dysphagia in individuals with cardiovascular disease and COVID-19
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Almeida, Tatiana Magalhães de

; Fernandes, Raquel Gama

; Binhardi, Vitor Della Rovere

; França, João Italo Dias

; Magnoni, Daniel

; Silva, Roberta Gonçalves da

CoDAS

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2024, Volume 36 Nº 5 elocation e20220112

Resumo: En | Texto: En | PDF: En

ABSTRACT Purpose Oropharyngeal dysphagia (OD) is one of the possible outcomes in patients hospitalized with COVID-19 and also in the population hospitalized for the treatment of cardiovascular disease. Thus, knowing the predictive risk factors for OD may help with referral and early intervention. This study aimed to verify the association of different factors with OD in hospitalized individuals with cardiovascular disease and COVID-19. Methods Cross-sectional clinical study approved by the Research Ethics Committee (4,521,771). Clinical evaluation of swallowing was carried out in 72 adult patients with cardiovascular disease and COVID-19 hospitalized from April to September 2020. Individuals under 18 years of age and without previous cardiovascular disease were excluded. The presence of general clinical and/or neurological complications, pronation, stay in the intensive care unit (ICU), orotracheal intubation (OTI), tracheostomy tube, oxygen support and age were considered as predictive risk factors for oropharyngeal dysphagia. Fisher's exact test, Mann Whitney test and logistic regression model were used for analysis. Results General clinical complications (p=0.001), pronation (p=0.003), ICU stay (p=0.043), in addition to the need for oxygen supplementation (p=0.023) and age (p= 0 .037) were statistically significant factors associated. The pronation (0.013) and age (0.038) were independently associated with dysphagia. OTI (p=0.208), tracheostomy (p=0.707) and the presence of previous cerebrovascular accidents (p=0.493) were not statistically significant. Conclusion In this study, age and prone position were factors independently associated with oropharyngeal dysphagia, complications such as the need for oxygen supplementation, in addition to the need for ICU admission, were also associated factors in the population.

https://doi.org/10.1590/2317-1782/20242022112en

Dynamics of plant organic matter decomposition in different agricultural landscapes
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Silva, João H. C. S.

; Barbosa, Alex da S.

; Gomes, Daniel da S.

; Aquino, Italo de S.

; Silva, Janaína R. da

Revista Caatinga

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Mar 2023, Volume 36 Nº 1 Páginas 135 - 144

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O funcionamento dos ecossistemas ou agroecossistemas depende, sobretudo, da interação solo-serapilheira. Assim, objetivouse avaliar a influência de diferentes sistemas de uso e manejo do solo sobre a dinâmica de decomposição dos resíduos vegetais de Azadirachta indica e Gliricidia sepium. O estudo foi conduzido em quatro sistemas de ocupação da terra, sendo eles: remanescente florestal, sistema agroflorestal (SAF), mandala agrícola e pastagem. A taxa de decomposição foi estimada com o uso de sacolas de nylon (litter bags), contendo 20 g de folhas de A. indica e G. sepium, que foram dispostas na superfície do solo de cada área por um período de 18, 36, 54, 72, 90 e 108 dias. Adotou-se um DIC, considerando cada área como um tratamento e quatro repetições a cada coleta, para ambas as espécies. Os dados foram submetidos a uma análise de regressão e as médias foram comparadas pelo teste Tukey (p<0,05). Após 108 dias, mais de 85 e 90% da fitomassa de A. indica e G. sepium, respectivamente, havia sido decomposta, independente do sistema avaliado, indicando que estas espécies apresentam rápida taxa de decomposição. O tempo de meia-vida (T½) do material vegetal variou de 16 a 23 dias no caso da G. sepium e de 25 a 37 dias no caso da A. indica, dependendo do sistema de uso da terra. A temperatura edáfica, o conteúdo de água do solo e as características físico-químicas da fração foliar são preditores da perda de massa. Esses conhecimentos podem fornecer importantes informações que viabilizem práticas de manejo florestal. depende sobretudo soloserapilheira. soloserapilheira serapilheira. serapilheira solo-serapilheira Assim terra eles florestal SAF, SAF , (SAF) pastagem litter bags, bags bags) 2 G 18 36 54 72 9 10 Adotouse Adotou se DIC coleta p<0,05. p005 p p<0,05 . 0 05 (p<0,05) 8 respectivamente decomposta avaliado meiavida meia vida T½ T (T½ 1 3 edáfica físicoquímicas físico químicas massa (SAF 5 7 p00 p<0,0 (p<0,05 (T p0 p<0, (p<0,0 p<0 (p<0, p< (p<0 (p< (p

ABSTRACT The functioning of ecosystems or agroecosystems is mainly dependent on the soil-litterfall interaction. Thus, the objective of this work was to evaluate the effect of different soil use and management systems on the dynamics of decomposition of plant residues of Azadirachta indica (neem) and Gliricidia sepium (gliricidia). The study was conducted in four land occupation systems, namely: remaining forest, agroforestry, agricultural mandala, and pasture. The decomposition rate was estimated using nylon bags (litter bags), containing 20 g of leaves of A. indica and G. sepium, which were arranged on the soil surface of each area for 18, 36, 54, 72, 90, and 108 days. A completely randomized design was used for each species, considering each area as one treatment, with four replications for each collection. The data were subjected to regression analysis and the means were compared by the Tukey's test (p<0.05). More than 85% and 90% of A. indica and G. sepium plant matters, respectively, had been decomposed after 108 days, regardless of the system evaluated, denoting that these species present high decomposition rates. The phytomass half-life time varied from 16 to 23 days for G. sepium and from 25 to 37 days for A. indica, depending on the land use system. Edaphic temperature, soil water content, and leaf physical and chemical characteristics are weight loss predictors. The results provide important information to enable forest management practices. soillitterfall litterfall interaction Thus neem (neem gliricidia. gliricidia . (gliricidia) namely agroforestry mandala pasture litter bags, , bags) 2 G 18 36 54 72 90 10 treatment collection Tukeys Tukey s p<0.05. p005 p p<0.05 0 05 (p<0.05) 85 matters respectively evaluated rates halflife half life 1 3 temperature content predictors practices (gliricidia 5 7 9 p00 p<0.0 (p<0.05 8 p0 p<0. (p<0.0 p<0 (p<0. p< (p<0 (p< (p

https://doi.org/10.1590/1983-21252023v36n115rc

ADOLESCENT IDIOPATHIC SCOLIOSIS: PROGRESSION OF UNTREATED CASES
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Schleder, Júlia Silva e Lima

; Santos, João Lucas dos

; Lima, Maurício Coelho

; Mistro Neto, Sylvio

; Rosa, André Frazão

; Pasqualini, Wagner

; Tebet, Marcos Antônio

; Cavali, Paulo Tadel Maia

; Risso Neto, Marcelo Italo

Coluna/Columna

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2023, Volume 22 Nº 2 elocation e262590

Resumo: En Pt Es | Texto: En Pt Es | PDF: En | PDF: Pt | PDF: Es

ABSTRACT Objective: This study aims to evaluate angular progression of patients with a diagnosis of Adolescent Idiopathic Scoliosis (AIS), that await surgical treatment. Methods: This is an observational and descriptive study. Data were collected for age at initial surgical indication, initial date and Cobb angle, date and Cobb angle of the follow-up visit, time elapsed between the initial and follow-up visit, and type of curve. All recorded Cobb angles were reviewed by the authors. Results: 86.1% of the individuals were women, the mean age of indication for surgical treatment was 13.34 years. The most common type of curve was Lenke 3 and the one that progressed the most was Lenke 4. The general average of annual progression was 9.89 degrees for the primary curves and 12.32 for the secondary curves, and the follow-up was, on average, 35.77 months. Conclusion: The progression of the magnitude of the curve increases during the wait for the definitive treatment of AIS, no matter which group of the Lenke classification the curve belongs to. The secondary curves present a progression rate of 12.32º/year, higher than the main curve, which presents a rate of 9.89º/year. The waiting time has been increasing over the years, which is evident compared to older publications. Level of Evidence IV; Type of Study: Prognostic Study.

RESUMO: Objetivo: Este estudo tem como objetivo avaliar a progressão do valor angular de indivíduos com diagnóstico de Escoliose Idiopática do Adolescente (EIA) não tratada, aguardando procedimento cirúrgico. Métodos: Este é um estudo observacional e descritivo. Foram coletados os seguintes dados dos pacientes: idade da indicação cirúrgica inicial, data da avaliação inicial e ângulo de Cobb, data e ângulo de Cobb nas consultas de seguimento, tempo decorrido entre as consultas inicial e de seguimento, bem como os tipos de curva. Todos os ângulos de Cobb registrados foram revisados pelos autores. Resultados: 86,1% dos indivíduos eram mulheres, a idade média de indicação de tratamento cirúrgico foi de 13,34 anos. O tipo de curva mais comum foi a Lenke 3 e a que mais progrediu foi a Lenke 4. A média geral de progressão anual foi de 9,89 graus para as curvas primárias e 12,32 para as curvas secundárias e o acompanhamento foi em média de 35,77 meses. Conclusão: A progressão da magnitude da curva aumentou durante a espera pelo tratamento definitivo da EIA, não importando em qual grupo da classificação de Lenke a curva pertence. As curvas secundárias apresentaram taxa de progressão de 12,32º/ano que é maior se comparada com a curva principal que apresenta taxa de 9,89º/ano. O tempo de espera vem aumentando com o passar dos anos, sendo evidente quando comparado com as publicações mais antigas. Nível de Evidência IV; Tipo de Estudo: Estudo Prognostico.

RESUMEN: Objetivo: Este estudio tiene como objetivo evaluar la progresión del valor angular de individuos no tratados diagnosticados con Escoliosis Idiopática del Adolescente (EIA), que están en espera de un procedimiento quirúrgico. Métodos: Se trata de un estudio observacional y descriptivo. Se recogieron datos de edad de indicación quirúrgica inicial, fecha inicial y ángulo de Cobb, fecha y ángulo de Cobb de la visita de seguimiento, tiempo transcurrido entre la visita inicial y de seguimiento y tipo de curva. Todos los ángulos de Cobb registrados fueron revisados por los autores. Resultados: El 86,1% de los individuos eran mujeres, la edad media de indicación del tratamiento quirúrgico fue de 13,34 años. El tipo de curva más común fue Lenke 3 y el que más progresó fue Lenke 4. El promedio general de progresión anual fue de 9,89 grados para las curvas primarias y 12,32 para las curvas secundarias y el seguimiento fue en promedio de 35,77 meses. Conclusión: La progresión de la magnitud de la curva aumenta durante la espera del tratamiento definitivo de la EIA, independientemente del grupo de la clasificación de Lenke al que pertenezca la curva. Las curvas secundarias presentan una tasa de progresión de 12,32º/año, superior a la curva principal que presenta una tasa de 9,89º/año. El tiempo de espera ha ido aumentando a lo largo de los años, lo cual es evidente al compararlo con publicaciones más antiguas. Nivel de Evidencia IV; Tipo de Estudio: Estudio Pronostico.

https://doi.org/10.1590/s1808-185120232202262590

Excluídos em nome da lei: práticas racistas no sistema jurídico da Guiana Inglesa
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Silva, João Italo de Oliveira e

Revista Brasileira de História

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Dez 2021, Volume 41 Nº 88 Páginas 107 - 129

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo A população de origem asiática no continente americano conviveu, no século XIX, com políticas restritivas, discursos preconceituosos e uma contínua estigmatização. O racismo estrutural consistiu em uma realidade que promoveu a exclusão política, econômica e jurídica, sempre calcadas em uma ideologia profundamente enraizada. Este artigo analisa como a legislação e o processo político conseguiram excluir indianos e chineses na colônia britânica da Guiana Inglesa. Partimos de memórias de ex-funcionários públicos, de cartas-denúncia, do relatório da Comissão de Inquérito e de outros documentos para perceber o papel do judiciário na exclusão dessas populações. Os textos de Sílvio de Almeida e de Grada Kilomba servem como base teórica para a compreensão do racismo estrutural dentro do Império Inglês.

Abstract The population of Asian origin in the American continent lived, in the 19th century, with restrictive policies, prejudiced speeches, and continuous stigmatization. Structural racism was a reality that promoted political, economic, and legal exclusion, always based on a deep-rooted ideology. This paper examines how legislation and the political process succeeded in excluding Indians and Chinese in the British colony of English Guiana. We start from the memories of former civil servants, letters of complaint, the report of the Commission of Inquiry, and other documents to understand the role of the judiciary in the exclusion of these populations. The texts by Silvio de Almeida and Grada Kilomba serve as the theoretical basis for understanding structural racism within the English Empire.

https://doi.org/10.1590/1806-93472021v41n88-07

Hesitation regarding the COVID-19 vaccine among medical students in Brazil
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Chaves, Ítalo Emanoel de Sousa

; Brito, Paulo Roberto Pinheiro

; Rodrigues, João Guilherme Bentes de Araújo

; Costa, Milena Silva

; Cândido, Estelita Lima

; Moreira, Maria Rosilene Cândido

Revista da Associação Médica Brasileira

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Out 2021, Volume 67 Nº 10 Páginas 1397 - 1402

Resumo: En | Texto: En | PDF: En

SUMMARY OBJECTIVE: This study aims to know the main determinants of hesitation to the vaccine against COVID-19 mentioned by medical students in Brazil. METHODS: A cross-sectional study with 250 students who answered the online questionnaire between December 18, 2020 and January 8, 2021. RESULTS: Most students (84%) mentioned the intention to take anti-COVID vaccine and 14% were hesitant. Information provided by governments (59.2%), the pharmaceutical industry (54.4%), and the press (51.6%) were the items that most generated vaccine hesitation. CONCLUSION: In the context of the COVID-19, vaccine hesitation is an additional concern because adherence to vaccination is a recurring challenge. The category of contextual influences predominated among the main determinants of anti-COVID vaccine hesitation expressed by medical students in Brazil, disfavoring vaccine adherence in this public.

https://doi.org/10.1590/1806-9282.20210379

Mandarin Brazil: representações raciais dos chineses na sociedade brasileira
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Silva, João Ítalo

História, Ciências, Saúde-Manguinhos

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Jun 2020, Volume 27 Nº 2 Páginas 687 - 689

Resumo: Pt | Texto: Pt | PDF: Pt

https://doi.org/10.1590/s0104-59702020000200021 374 downloads

Insegurança alimentar e nutricional de famílias usuárias da Estratégia Saúde da Família em dois municípios paraibanos, Brasil
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Santos, Eduarda Emanuela Silva dos

; Oliveira, Maria Mônica de

; Bernardino, Ítalo de Macedo

; Pedraza, Dixis Figueroa

Ciência & Saúde Coletiva

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Mai 2020, Volume 25 Nº 5 Páginas 1607 - 1617

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste artigo é avaliar fatores associados à insegurança alimentar e nutricional de famílias com crianças menores de 5 anos de idade residentes em áreas de abrangência da Estratégia Saúde da Família. Estudo transversal que envolveu 406 famílias de dois municípios da Região Metropolitana de João Pessoa, Paraíba. Para a avaliação da segurança alimentar e nutricional das famílias foi utilizada a Escala Brasileira de Insegurança Alimentar. Os determinantes da insegurança alimentar moderada/grave foram analisados por meio de Árvore de Decisão. A insegurança alimentar e nutricional atingiu 71,4% das famílias. A insegurança alimentar moderada/grave (32%) associou-se, primeiramente, ao benefício do Programa Bolsa Família, além de à família constituída por crianças menores de 2 anos, ao menor nível socioeconômico e à disfunção familiar. Os resultados mostram prevalências elevadas de insegurança alimentar e nutricional, cujos graus mais graves sugerem a importância de intervenções direcionadas a melhorias do Programa Bolsa Família, nas condições dos domicílios com crianças menores de 2 anos, na situação socioeconômica das famílias e na funcionalidade familiar.

Abstract The objective of this article is to evaluate factors associated with food and nutritional insecurity in families with children under 5 years of age living in areas covered by the Family Health Strategy. Cross-sectional study involving 406 families from two municipalities in the Metropolitan Region of João Pessoa, Paraíba. The Brazilian Food Insecurity Scale was used to assess the families’ food and nutritional security. The determinants of moderate/severe food insecurity were analyzed using the Decision Tree. Food and nutritional insecurity reached 71.4% of families. Moderate/severe food insecurity (32%) was primarily associated with the benefit of the Family Allowance (Bolsa Família) Program, and also with family composition consisting of children under 2 years of age, lower socioeconomic status, and family dysfunction. The results showed high prevalence of food and nutritional insecurity whose more serious levels suggest the importance of interventions aimed at improving the Family Allowance Program for the conditions of households with children under 2 years of age, socioeconomic situation of families, and functionality of families.

https://doi.org/10.1590/1413-81232020255.33412019 1478 downloads

10.

Insegurança alimentar e nutricional de famílias usuárias da Estratégia Saúde da Família em dois municípios paraibanos, Brasil
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Santos, Eduarda Emanuela Silva dos

; Oliveira, Maria Mônica de

; Bernardino, Ítalo de Macedo

; Pedraza, Dixis Figueroa

Ciência & Saúde Coletiva

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Mai 2020, Volume 25 Nº 5 Páginas 1607 - 1617

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232020255.33412019

11.

Risk factors for oropharyngeal dysphagia in cardiovascular diseases
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ALMEIDA, Tatiana Magalhães de

; GOMES, Lívia Maria Silva

; AFONSO, Débora

; MAGNONI, Daniel

; MOTA, Isabela Cardoso Pimentel

; FRANÇA, João Ítalo Dias

; SILVA, Roberta Gonçalves da

Journal of Applied Oral Science

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2020, Volume 28 elocation e20190489

Resumo: En | Texto: En | PDF: En

Abstract Some conditions consolidated as risk factors for oropharyngeal dysphagia have already been identified in other diseases, such as neurological. Studies on cardiovascular diseases concentrate in individuals in the postoperative period; thus, it is unknown if these same factors occur in individuals hospitalized for clinical or surgical treatment of these diseases. Objective to correlate predictive risk factors for oropharyngeal dysphagia in individuals with cardiovascular disease admitted at a reference cardiology hospital. Methodology This is a retrospective clinical study. Medical records of 175 individuals hospitalized for clinical and/or surgical treatment at a reference cardiology hospital from January to June 2017, attendants of the Speech-Language Pathology and Nutrition team, were analyzed. Of these, 100 records were included in the study: 41 females and 59 males (mean age 67.56 years). Deaths and individuals from 0 to 18 years were excluded. Stroke, malnutrition, age and prolonged orotracheal intubation were considered predictive risk factors for oropharyngeal dysphagia. Mann-Whitney test and Fisher's test were used for statistical analysis. Results Stroke (OR=2.93 p=0.02), malnutrition (OR=2.89 p=0.02) and prolonged orotracheal intubation (OR=3.94 p=0.02) were statistically significant predictors for oropharyngeal dysphagia within this population. Age below 80 years was not significant (p=0.06), but within octogenarians, significance was found (p=0.033). Conclusion Stroke, malnutrition, prolonged orotracheal intubation and age > 80 years are predictive risk factors for oropharyngeal dysphagia in adult population with cardiovascular diseases.

https://doi.org/10.1590/1678-7757-2019-0489 1620 downloads

12.

An Overview of Laser Engineered Net Shaping of Ceramics
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Camargo, Italo Leite de

; Lovo, João Fiore Parreira

; Erbereli, Rogério

; Coelho, Reginaldo Teixeira

; Silva, Iris Bento da

; Fortulan, Carlos Alberto

Matéria (Rio de Janeiro)

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2020, Volume 25 Nº 1 elocation e-12590

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO A manufatura aditiva (AM) tem proporcionado grande versatilidade na geometria e em materiais, permitindo que novos produtos e processos sejam criados em diversas áreas. Deposição Direta de Energia (DED) é um processo de manufatura aditiva criado em 1995 que permite a fabricação de componentes metálicos e cerâmicos com alta densidade sem a necessidade de etapas posteriores, a exemplo de sinterização ou infiltração. Este artigo objetiva o estudo do estado da arte do processo DED relacionado à cerâmica. Partindo da geração de uma linha do tempo da manufatura aditiva, que inclui os marcos relacionados à Deposição Direta de Energia, foi realizada uma revisão sistemática em que os artigos foram agrupados em 3 categorias: revestimento cerâmico, AM de cerâmica e AM de compósitos com reforços cerâmicos. Para cada categoria foram analisados, classificados e resumidos aspectos referentes às matérias primas, substratos de deposição, principais aplicações, parâmetros de processo e propriedades. A maior parte dos trabalhos referente à categoria da manufatura aditiva cerâmica está relacionada com a fabricação da alumina, sendo que propriedades já são similares às produzidas por processos convencionais de manufatura. Trabalhos recentes utilizaram a vibração ultrassônica para homogeneizar o material em processo, reduzindo trincas e melhorando as propriedades mecânicas. A categoria AM de compósitos com reforços cerâmicos tem sido empregada para criar materiais compósitos com gradiente funcional de elevada dureza, enquanto que a categoria de revestimentos cerâmicos tem sido majoritariamente utilizada para fabricação de revestimentos biocompatíveis com elevada dureza e baixa taxa de desgaste. De modo geral, é certo que o advento dessa tecnologia vai ocupar fatia importante da manufatura cerâmica.

ABSTRACT Additive manufacturing (AM) has provided huge versatility in geometry and materials, allowing new products and processes in several areas to be created. Laser Engineered Net Shaping (LENS) is an additive manufacturing process created in 1995 that allows building high-density metals and ceramics parts with no need for further operation. This manuscript aims to study the scientific literature about the process of Laser Engineered Net Shaping related to ceramics. After a systematic review, the articles were grouped into three categories: ceramic coating and AM of ceramics and AM of composites with ceramic reinforcement. Raw materials, substrates, applications, process parameters, and the obtained properties were analyzed and summarized for each group. Most of the additive manufacturing of ceramic parts are related to alumina, which present similar properties when compared to the traditionally manufactured ones. Recent works have the aid of an ultrasonic vibration to homogenize the in-process material, reduce cracks and improve mechanical properties. The additive manufacturing of composites with ceramic reinforcement has been used to create functionally graded composites materials with increased hardness, while the ceramic coating has been employed to manufacture biocompatible coating with increased hardness and low wear rate. Moreover, an additive manufacturing timeline including Laser Engineered Net Shaping landmarks is presented.

https://doi.org/10.1590/s1517-707620200001.0916 1483 downloads

13.

Calcium partition in Minas Padrão cheese and its bioaccessibility during ripening time
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PEREIRA, João Pablo Fortes

; MAGESTE, Ana Carolina CAMPOS, Náira da Silva SOUSA, Rafael Arromba de FRANCISQUINI, Júlia d’Almeida PERRONE, Ítalo Tuler CARVALHO, Antônio Fernandes de NUNES, Renato Moreira MARTINS, Marta Fonseca SILVA, Paulo Henrique da Fonseca da

Food Science and Technology

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Dez 2019, Volume 39 Nº 4 Páginas 859 - 866

Resumo: En | Texto: En | PDF: En

Abstract Nutritionally, cheese and other dairy products have been highlighted especially as a calcium source. Access to minerals is dependent on variables related to diet, lifestyle, and also the health status. This study aimed to evaluate the bioaccessibility and calcium partition in Minas Padrão cheese over its ripening period for experimentally obtained samples. The cheese of the study has been manufactured using two different technologies (A and B). Also to evaluate the evolution of pH over cheese ripening and the influence of calcium partitions in its bioaccessibility along the cheese ripening period. The mean values found for total calcium content were (549 mg⋅100 g-1 – A and 644 mg⋅100 g-1 – B). For calcium in the aqueous phase on average 460 mg⋅100 g-1 – A and 404 mg⋅100 g-1 – B. These and other changes found are possibly due to physicochemical and biochemical changes, especially with respect to pH variations. Calcium bioaccessibility decreased in the beginning and then incresed in the end of the ripening period. The results obtained in this work hopefully may allow further studies and the development of products in which calcium bioaccessibility might be indicated on the product`s label accordingly to its ripening time.

https://doi.org/10.1590/fst.12518 536 downloads

14.

Evolution of soluble solid content and evaporation rate curves during the manufacture of dulce de leche (dl)
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FRANCISQUINI, Júlia d’Almeida PEREIRA, João Pablo Fortes PINTO, Michele da Silva CARVALHO, Antônio Fernandes PERRONE, Ítalo Tuler SILVA, Paulo Henrique da Fonseca da

Food Science and Technology

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Mar 2019, Volume 39 Nº 1 Páginas 78 - 82

Resumo: En | Texto: En | PDF: En

Abstract Dulce de leche is an evaporated dairy product that can be manufactured in different types of pots or pans. The manufacturing endpoint for dulce de leche can be determined by measuring the soluble solids content. We investigated the evaporation rates and the evaporative capacity of atmospheric pressure evaporators (pans) during the manufacture of dulce de leche. During manufacturing, four different formulations were subjected to soluble solids content determination by refractometry. In addition, the mass balance was used to determine the yield and evaporation rate. A low coefficient of variation and amplitude was found for soluble solids content, indicating standardization and uniformity during fabrication. We also observed a gradual increase in the latter throughout manufacture, without significant differences between the times. The evaporated water mass rate and its respective equation allow to reproduce the same characteristics of the experimental product in experimental and industrial production of dulce de leche.

https://doi.org/10.1590/fst.26617 2168 downloads

15.

REAL TIME PPP APPLIED TO AIRPLANE FLIGTHT TESTS
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Monico, João Francisco Galera

; Marques, Haroldo Antonio

; Tsuchiya, Ítalo

; Oyama, Rogério Takeshi

; Queiroz, William Robson Silva de Souza, Mauricio Cardoso de Wentz, Jens Peter

Boletim de Ciências Geodésicas

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2019, Volume 25 Nº 2 elocation e2019009

Resumo: En | Texto: En | PDF: En

Abstract The availability in real time of GNSS satellites orbits, clock corrections and code and phase biases provided the possibility of application of Real Time Precise Point Positioning (RTPPP). This paper presents the methodology concerning RTPPP and application to kinematic trajectories of airplane flight tests, but without using the carrier phase bias. So, it is PPP float solution. It requires RT positioning estimation, task that most of time presents certain difficulties due to loss of communication or of satellites during maneuvers of the airplane. However, if the corrections become unavailable for a certain period of time, the system starts using the ultra-rapid IGS orbits. The experiments were accomplished taking into account a case simulating RT and another in fact RT, but storing data and corrections for post processing. The PPP solutions obtained either simulating RT or in RT were compared against the PPP post processed solution that uses the final clock and orbit corrections. Then, statistics were generated to analyze the quality of both results. They were applied to kinematic trajectory that on average was 360 km/h, reaching about 600 km/h. The results provided accuracy better than the requisites for such cases which is of about 80 cm in height.

https://doi.org/10.1590/s1982-21702019000200009 929 downloads

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