ABSTRACT Processing residues are still one of the main obstacles in the fishing industry due to waste and environmental impact. With that, ways of reusing these residues are researched to generate new products with different applications. The objective of this work was to develop and evaluate protein films obtained from mechanically separated meat (MSM) of Nile tilapia (Oreochromis niloticus) filleting residues. To get the films, the casting technique was used, varying their composition in relation to the amount of protein (1.0, 1.5 and 2.0%) and glycerol (0.0, 0.1 and 0.2%), creating a 32 factorial plan, with 9 treatments. The films were characterized in terms of color, opacity, water solubility, mechanical properties and water vapor permeability (WVP). In the end, a yield of 18.70% of Nile tilapia myofibrillar proteins (MPs) and a post-lyophilization protein content of 87.33% were obtained. It was concluded that the film that presented the best result in all the characteristics analyzed was the one with 1.0% of MPs and 0.1% of glycerol. impact applications MSM (MSM Oreochromis niloticus used 1.0, 10 1 0 (1.0 15 5 1. 2.0% 20 2 0.0, 00 (0.0 01 0. 0.2%, 02 0.2% , 0.2%) 3 plan treatments color opacity solubility WVP. WVP . (WVP) end 1870 18 70 18.70 (MPs postlyophilization post lyophilization 8733 87 33 87.33 1.0 (1. 2.0 0.0 (0. 0.2 (WVP 187 7 18.7 873 8 87.3 (1 2. (0 18. 87. (

RESUMEN: Este estudio tuvo como objetivo evaluar los aspectos morfológicos craneofaciales de los pacientes con síndrome de Sheehan (SHS). Se realizó un estudio observacional con 19 mujeres diagnosticadas con SHS y 19 controles asociados por edad y sexo. Se obtuvieron radiografías cefalométricas laterales y se analizaron 30 medidas lineales y angulares mediante el software Radiocef Studio 2. La edad media de los pacientes fue de 65,47 ± 10,19 años. Los principales hallazgos fueron proposición maxilar (52,63 %) y mandíbula (52,63 %) con respecto a la base del cráneo, prognatismo mandibular en 73,68 %, patrón de crecimiento profundo en 42,1 %, aumento del plano mandibular en 36,84 % y reducción de la altura facial anterior. El grupo SHS mostró diferencias estadísticamente significativas en SNB (p=0,026), N-Me (p=0,006), longitud del paladar blando (p=0,011) y Ena-Me (p<0,001) en comparación con los controles. El análisis de la puntuación de la desviación estándar reveló valores alterados en relación con las longitudes maxilares y mandibulares totales. El SHS mostró una morfología craneofacial alterada, caracterizada por prognatismo maxilomandibular, tipo braquifacial, aumento del plano mandibular y reducción de la longitud del velo del paladar. Este estudio informa hallazgos novedosos en SHS.

ABSTRACT: This study aimed to assess the craniofacial morphologic aspects of Sheehan’s syndrome (SHS) patients.An observational study was performed with 19 women diagnosed with SHS and 19 controls matched by age and sex. Lateral cephalometric radiographs were obtained, and 30 linear and angular measurements were analyzed using the Radiocef Studio 2 software. The mean age of patients was 65.47 ± 10.19 years. The main findings were propositioned maxilla (52.63 %) and mandible (52.63 %) relative to the cranial base, mandibular prognathism in 73.68 %, deep growth pattern in 42.1 %, increased mandibular plane in 36.84 %, and reduction in anterior facial height. The SHS group showed statistically significant differences in SNB (p=0.026), N-Me (p=0.006), soft palate length (p=0.011), and Ena-Me (p<0.001) in comparison with controls. The standard deviation score analysis revealed altered values in relation to total maxillary and mandibular lengths. SHS showed altered craniofacial morphology, characterized by maxillo- mandibular prognathism, brachyfacial type, increased mandibular plane, and reduction in soft palate length. This study reports novel findings in SHS.

Resumo Fundamento: A síndrome da apneia obstrutiva do sono (SAOS) é uma doença crônica, progressiva, com alta morbimortalidade. Encontra-se subdiagnosticada, principalmente entre mulheres. Objetivo: Estudar a prevalência de alto risco para SAOS globalmente e para as categorias do Questionário de Berlim (QB), e avaliar a confiabilidade do uso do QB na população estudada. Métodos: Estudo observacional, transversal de indivíduos cadastrados no Programa Médico de Família de Niterói, selecionados aleatoriamente, com idade entre 45 e 99 anos, com coleta entre agosto/2011 e dezembro/2012. Variáveis associadas com cada uma das categorias do QB e com o alto risco para SAOS (global) (valor p<0,20) foram incluídas em modelos de regressão logística (valor p<0,05). Resultados: Do total (616), 403 (65,4%) indivíduos disseram roncar. A prevalência de alto risco para SAOS foi de 42,4%, sendo de 49,7% para a categoria I, 10,2% para a categoria II e 77,6% para a categoria III. Conclusão: O QB apresentou uma confiabilidade aceitável quando retiradas as perguntas 'alguém notou que você para de respirar quando está dormindo' e 'cochilar/dormir ao volante', o que deve ser testado em estudos com populações com maioria de mulheres e de baixa escolaridade. Dado o peso das doenças e riscos associados à SAOS, seria importante realizar futuras investigações para validar novos instrumentos ou adaptar o QB para melhor rastreamento da SAOS.

Abstract Background: Obstructive sleep apnea syndrome (OSAS) is a chronic, progressive disease with high morbidity and mortality. It is underdiagnosed, especially among women. Objective: To study the prevalence of high risk for OSAS globally and for the Berlin Questionnaire (BQ) categories, and to evaluate the reliability of the BQ use in the population studied. Methods: Observational, cross-sectional study with individuals from the Niterói Family Doctor Program, randomly selected, aged between 45 and 99 years. The visits occurred between August/2011 and December/2012. Variables associated with each BQ category and with high risk for OSAS (global) were included in logistic regression models (p < 0.05). Results: Of the total (616), 403 individuals (65.4%) reported snoring. The prevalence of high risk for OSA was 42.4%, being 49.7% for category I, 10.2% for category II and 77.6% for category III. Conclusion: BQ showed an acceptable reliability after excluding the questions Has anyone noticed that you stop breathing during your sleep? and Have you ever dozed off or fallen asleep while driving?. This should be tested in further studies with samples mostly comprised of women and low educational level individuals. Given the burden of OSAS-related diseases and risks, studies should be conducted to validate new tools and to adapt BQ to better screen OSAS.

Sidastrum paniculatum (L.) Fryxell belongs to the family Malvaceae and is popularly known as "malva roxa" or "malvavisco". The phytochemical study of the hexane, CHCl3 and EtOAc phases from the crude ethanol extract of S. paniculatum led to the isolation of six compounds: a mixture of β-sitosterol and stigmasterol, 4-methoxy-3-hydroxybenzoic acid, 4-methoxy-3-hydroxybenzaldehyde, N-trans-feruloyltyramine and kaempferol-3-O-β-D-(6''-E-p -coumaroyl) glucoside. The structural identification of the compounds was made on the basis of spectroscopic methods such as IR, ¹H and 13C NMR with the aid of including two-dimensional techniques, besides comparison with literature data. The β-sitosterol and stigmasterol mixture showed a significant anti-inflammatory activity.

O presente trabalho avaliou a produtividade e as características físicas e químicas dos frutos de goiabeira 'Paluma' em diferentes estádios de maturação, sob a influência de adubações nitrogenada e potássica, em Petrolina-PE. As plantas foram submetidas à aplicação de 67 kg N + 33 kg K2O, 133 kg N + 67 kg K2O, 200 kg N + 100 kg K2O and 267 kg N + 133 kg K2O por hectare, sendo os frutos avaliados nos estádios de maturação 2; 3; 4 e 5, caracterizados conforme a cor da casca. As maiores doses de N e K resultaram em maiores produtividades, mas as aplicações de 200 kg de N + 100 kg de K por hectare favoreceram a qualidade do fruto, resultando em menor degradação de ácido ascórbico e preservação da firmeza da polpa. As principais mudanças que ocorreram entre os estádios 4 e 5, quando o fruto apresentaria condições ideais para consumo, foram relativas ao acúmulo de sólidos solúveis e de açúcares solúveis.

Yield and physical and chemical characteristics of 'Paluma' guava fruit were evaluated as a function of the harvest at different maturity stages, under influence of nitrogen and potassium fertilization, in Petrolina, State of Pernambuco, Brazil. Fertilizer rates were 67 kg N + 33 kg K2O, 133 kg N + 67 kg K2O, 200 kg N + 100 kg K2O and 267 kg N + 133 kg K2O per hectare. Fruits were evaluated at maturity stages 2, 3, 4 and 5, established according to peel color. Higher doses of N and K induced higher yields. Nevertheless, fertilization with 200 kg of N + 100 kg of K per hectare improved fruit quality, delaying ascorbic acid breakdown and conserving pulp firmness. Main changes took place at maturity stages 4 and 5, when the fruit should present ideal conditions for consumption, namely the increase on soluble solids and soluble sugars content.

A goiabeira (Psidium guajava L.) cv. Paluma é cultivada no Vale do São Francisco, tanto para consumo in natura como para industrialização. Apesar da sua importância, existe pouco conhecimento científico em relação à fisiologia, nutrição mineral, irrigação e fertirrigação da goiabeira. O objetivo deste trabalho foi avaliar o efeito das condições meteorológicas e das diferentes doses de N e K, aplicados via fertirrigação, no teor foliar de açúcares redutores, açúcares solúveis totais, amido, sacarose, aminoácidos e proteínas totais. O experimento de campo foi desenvolvido no Campo Experimental Bebedouro e as análises bioquímicas no Laboratório de Sementes e Fisiologia Vegetal, ambos localizados na Embrapa Semi-Árido, Petrolina-PE. Foram utilizadas as doses de 200 g N e 100 g K2O; ; 400 g N e 200 g K2O; 600 g N e 300 g K2O e 800 g N e 400 g K2O por planta. O experimento foi disposto em um delineamento em blocos ao acaso, com quatro tratamentos e cinco blocos. As condições meteorológicas influenciaram na fotossíntese das plantas, que, por sua vez, interferiu no metabolismo das mesmas. Para cada parâmetro avaliado, as goiabeiras apresentaram respostas específicas à fertirrigação com N e K. As condições meteorológicas durante os períodos avaliados influenciaram na resposta das goiabeiras à fertirrigação com N e K.

The guava (Psidium guajava L.) cv. Paluma has been cultivated in São Francisco Valley, Northeastern of Brazil, for in natura consumption and processing purposes. In spite of its importance, there are few scientific knowledge regarding guava physiology, nutrition, irrigation and fertigation. The objective of this work was to evaluate the effect of weather conditions and different concentrations of N and K applied by fertigation in foliar contents of reducing sugars, total soluble sugars, starch, sucrose, amino acids, and proteins. The field experiment was carried out at Bebedouro Experimental Field and the biochemical evaluations at the Laboratory of Seed and Plant Physiology, both located at Embrapa Semi-Árido, Petrolina-PE. The doses of 200 g N and 100 g K2O; 400 g N and 200 g K2O; 600 g N and 300 g K2O; and 800 g N and 400 g K2O per plant were applied in an experiment field. The experimental design was totally randomized blocks, with four treatments and five blocks. The weather conditions influenced the plant photosynthesis, which affects the plants metabolism. Guava presented specific responses to N and K fertigation for each parameter evaluated. The weather conditions during the evaluation period influenced guava responses to N and K fertigation.