ABSTRACT Objective To determine the maternal and early childhood factors associated with asthma and obesity in children aged 6 to 7 years. Methods A case-control study conducted with children aged 6 to 7 years. Applications with questions about asthma symptoms in the last 12 months, maternal and childhood data in the first 2 years of life, and anthropometric data were collected. Children who presented asthma symptoms were considered as cases and those without asthma symptoms were considered as controls, later divided into two subgroups that were eutrophic or overweight/obesity. Logistic regression was performed to estimate the association between asthma symptoms (adequate weight and overweight/obesity) and gestational and personal factors, calculating odds ratio and 95% confidence interval (95%CI). Values of p<0.05 were considered significant. Results Two hundred and one children were evaluated, 25.4% had asthma symptoms, 37.2% of them were overweight/obesity. Waist circumference, triceps skinfold, and body mass index were higher in the group with overweight/obesity asthma symptoms compared to no asthma symptoms (p<0.05). Factors significantly associated with asthma and overweight/obesity symptoms included: the maternal history of asthma (odds ratio of 3.73; 95%CI: 1.10-12.6) and hypertension during pregnancy (odds ratio of 3.29; 95%CI: 1.08-9.94). Conclusion Maternal history of asthma and hypertension during pregnancy increased the chances of children, at 6 and 7 years of age, having symptoms of asthma and obesity.

A produção de vinhos ao norte de Curitiba, Paraná, Brasil, especificamente nas cidades de Colombo e Almirante Tamandaré, está baseada principalmente no uso de uvas Vitis labrusca var. Bordô (Ives). Os parâmetros - açúcar total, teor alcoólico, pH e acidez total - foram analisados em amostras de vinhos tintos das safras 2007 e 2008 por metodologias oficiais. Além disso, também foram determinadas as concentrações de compostos fenólicos totais, flavonoides e taninos por métodos colorimétricos e a atividade antioxidante foi determinada pelo método do radical 2,2-difenil-1-picrilhidrazila (DPPH). Os compostos fenólicos foram identificados por Cromatografia Líquida de Alta Eficiência. A concentração de compostos fenólicos totais das amostras de vinho variou entre 1582,35 e 2896,08 mg de ácido gálico.L-1, com a maior parte correspondendo à concentração de flavonoides. Na faixa de concentração destes compostos, não foi encontrada relação direta entre compostos fenólicos e atividade antioxidante. Entre os compostos fenólicos identificados, os ácidos clorogênico e cafeico foram os componentes majoritários. Com o uso de três componentes principais, foi possível explicar 81,36% da variância total das amostras estudadas. A diferenciação entre as safras não foi possível com o uso da análise de componentes principais.

Wine production in the northern Curitiba, Paraná, Brazil, specifically the communes of Colombo and Almirante Tamandaré, is based mainly on the utilization of Vitis labrusca grapes var. Bordô (Ives). Total sugar content, pH, and total acidity were analyzed in red wine samples from 2007 and 2008 vintages following official methods of analysis. Moreover, total phenolic, flavonoid, and tannin contents were analyzed by colorimetric methodologies and the antioxidant activity was determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical methodology. Phenolic compounds were identified by high performance liquid chromatography. The total phenolic content of wine samples presented concentrations varying between 1582.35 and 2896.08 mg gallic acid.L-1 since the major part corresponds to flavonoid content. In these compounds' concentration range, a direct relationship between phenolic compounds content and levels of antioxidant activity was not observed. Among the identified phenolic compounds, chlorogenic, caffeic, and syringic acids were found to be the major components. Using three principal components, it was possible to explain 81.36% of total variance of the studied samples. Principal Components Analysis does not differentiate between vintages.