SUMMARY Beckwith-Wiedemann syndrome (BWS) is a common genetic congenital disease characterized by somatic overgrowth and its broad clinical spectrum includes pre- and post-natal macrosomia, macroglossia, visceromegaly, increased risk of neonatal hypoglycemia, and development of embryonic tumors. BWS occurs due to genetic/epigenetic changes involving growth-regulating genes, located on region 11p15, with an important genotype-phenotype correlation. Congenital adrenal hyperplasia (CAH) comprises a spectrum of autosomal recessive diseases presenting a variety of clinical manifestations due to a deficiency in one of the enzymes involved in cortisol secretion. Early diagnosis based on newborn screening prevents the adrenal crisis and early infant death. However, high 17-hydroxyprogesterone (17-OHP) levels can occur in newborns or premature infants without CAH, in situations of stress due to maternal or neonatal factors. Here, we report new cases of false-positive diagnosis of 21-hydroxylase deficiency during newborn screening – two girls and one boy with BWS. Methylation-specific multiplex ligation-dependent probe amplification revealed a gain of methylation in the H19 differentially methylated region. Notably, all three cases showed a complete normalization of biochemical changes, highlighting the transient nature of these hormonal findings that imitate the classical form of CAH. This report sheds light on a new cause of false-positive 21-hydroxylase deficiency diagnosis during newborn screening: Beckwith-Wiedemann syndrome. BeckwithWiedemann Beckwith Wiedemann (BWS pre postnatal post natal macrosomia macroglossia visceromegaly hypoglycemia tumors geneticepigenetic epigenetic growthregulating growth regulating genes 11p15 p genotypephenotype genotype phenotype correlation CAH (CAH secretion death However 17hydroxyprogesterone hydroxyprogesterone 17 17OHP OHP (17-OHP factors Here falsepositive false positive 21hydroxylase hydroxylase 21 Methylationspecific Methylation specific ligationdependent ligation dependent H H1 Notably 11p1 1 2 11p

Resumen Los inhibidores del punto de control inmunitario han demostrado mejorar el pronóstico de múltiples enfer medades oncológicas. Recientemente se han reportado eventos adversos relacionados a la inmunoterapia. La to xicidad neurológica es poco frecuente. Se presenta el caso de un paciente con encefalitis relacionada con inhibido res del punto de control inmunitario.

Abstract Immune checkpoint inhibitors have been shown to improve the prognosis of multiple oncological diseases. Recently, adverse events related to immunotherapy have been reported. Neurologic toxicity is infrequent. We pre sent the case of a patient with encephalitis associated to immune checkpoint inhibitors.

ABSTRACT The technology of 3D printing has been studied by different researchers, due to the possibility of producing solid objects swiftly, time reduction, labor with fewer failures the construction process. One of the challenges to be overcome is related to the development of mixtures promising. Thus, research aimed at the technology of cementitious materials is necessary to develop extrudable and sustainable mixtures. This article aimed to investigate the potential use of (FA) and (MK) in cementitious materials for application in three-dimensional printing (3D) by checking the aspects of constructibility. In the first stage, tests of normal consistency and initial and final setting time were carried out on pastes, with calcium oxide 4% and addition of (FA) and (MK) in the percentages of 8%, 10% and 15% in relation to the cement mass, in order to establish an ideal water / cement ratio. In the second stage, given a pre-determined trace of 1: 1.5, in mass, the viscosity, yield stress, extrudability and verticality tests were carried out on the cementitious materials developed in the first stage. It was observed that for the aspects related to the normal cement consistency and initial and final setting time, the paste with 15% substitution (FA) presented a longer initial setting time when compared to pastes with (MK) added. yield stress, materials with 15% substitution (FA) and without superplasticizer additive showed favorable results in the relation of the initial and final yield stress, as the mixture of 15% (MK) with 0.4% superplasticizer additive. and, therefore, they were considered promising because they were subjected to extrudability and verticality tests. Thus, it is concluded that considering the constructibility applied to prototyping, cementitious materials with 15% substitution (FA) and (MK) in relation to the cement mass present results considered relevant for the application in 3D printing. D researchers swiftly reduction process Thus FA (FA MK (MK threedimensional three dimensional (3D stage 4 8 8% 10 15 ratio predetermined pre determined 1 5 1.5 viscosity stress added 04 0 0.4 therefore prototyping 1. 0.

Objetivou-se analisar a atuação do Conselho Nacional de Saúde no núcleo do processo decisório da política de saúde entre 2014-2017. A análise foi baseada nos projetos políticos em disputa na arena política da saúde e nos projetos dos governos de Dilma e de Temer. Com a mudança no projeto de governo, o Conselho passou a atuar pela via judicial, além de pelas vias social e parlamentar, passando do alinhamento (crítico) à franca oposição, até sua neutralização com o boicote da participação do Conselho nas discussões de pautas da política de saúde nos anos 2016-2017. Embora não tenha tido poder suficiente para mudar a correlação de forças em torno do desmonte do Sistema Único de Saúde (SUS), o Conselho figurou-se em um bloco político de resistência e de enfrentamento em defesa do SUS constitucional.

This study aimed to analyze the role of the National Health Council in the core of the decision-making process of health policy in the period 2014-2017. The analysis was based on the political disputed projects in the health policy sphere and on the government projects of former Presidents Dilma Rousseff and Michel Temer. Due to the government’s project change, in addition to the social and parliamentary channels, the Council started to act through the judicial channel as well, moving from critical alignment to outright opposition until its neutralization, with the Council’s participation boycott in the health policy agenda discussions in the period 2016-2017. Although it did not have enough power to change the balance of forces surrounding the deconstruction of the Brazilian National Health System (SUS), the Council was part of a political bloc of resistance and confrontation in defense of the constitutional SUS.

El objetivo fue el análisis de la actuación del Consejo Nacional de Salud en el núcleo del proceso de decisión de la política de salud entre 2014-2017. El análisis tuvo como base los proyectos políticos en disputa en la arena política de la salud y en los proyectos de los gobiernos Dilma y Temer. Con el cambio en el proyecto de gobierno, el Consejo pasó a actuar, además de en las vías social y parlamentaria, en la vía judicial, pasando del alineamiento (crítico) a la franca oposición, hasta su neutralización, con el boicot de la participación del Consejo en las discusiones de pautas de la política de salud en los años 2016-2017. Aunque no haya tenido poder suficiente para cambiar la correlación de fuerzas alrededor del desmontaje del Sistema Brasileño de Salud (SUS), el Consejo se configuró como un bloque político de resistencia y de enfrentamiento, en defensa del SUS constitucional.

Objetivou-se analisar a atuação do Conselho Nacional de Saúde no núcleo do processo decisório da política de saúde entre 2014-2017. A análise foi baseada nos projetos políticos em disputa na arena política da saúde e nos projetos dos governos de Dilma e de Temer. Com a mudança no projeto de governo, o Conselho passou a atuar pela via judicial, além de pelas vias social e parlamentar, passando do alinhamento (crítico) à franca oposição, até sua neutralização com o boicote da participação do Conselho nas discussões de pautas da política de saúde nos anos 2016-2017. Embora não tenha tido poder suficiente para mudar a correlação de forças em torno do desmonte do Sistema Único de Saúde (SUS), o Conselho figurou-se em um bloco político de resistência e de enfrentamento em defesa do SUS constitucional.

This study aimed to analyze the role of the National Health Council in the core of the decision-making process of health policy in the period 2014-2017. The analysis was based on the political disputed projects in the health policy sphere and on the government projects of former Presidents Dilma Rousseff and Michel Temer. Due to the government’s project change, in addition to the social and parliamentary channels, the Council started to act through the judicial channel as well, moving from critical alignment to outright opposition until its neutralization, with the Council’s participation boycott in the health policy agenda discussions in the period 2016-2017. Although it did not have enough power to change the balance of forces surrounding the deconstruction of the Brazilian National Health System (SUS), the Council was part of a political bloc of resistance and confrontation in defense of the constitutional SUS.

El objetivo fue el análisis de la actuación del Consejo Nacional de Salud en el núcleo del proceso de decisión de la política de salud entre 2014-2017. El análisis tuvo como base los proyectos políticos en disputa en la arena política de la salud y en los proyectos de los gobiernos Dilma y Temer. Con el cambio en el proyecto de gobierno, el Consejo pasó a actuar, además de en las vías social y parlamentaria, en la vía judicial, pasando del alineamiento (crítico) a la franca oposición, hasta su neutralización, con el boicot de la participación del Consejo en las discusiones de pautas de la política de salud en los años 2016-2017. Aunque no haya tenido poder suficiente para cambiar la correlación de fuerzas alrededor del desmontaje del Sistema Brasileño de Salud (SUS), el Consejo se configuró como un bloque político de resistencia y de enfrentamiento, en defensa del SUS constitucional.

Abstract The atypical clinical features in multiple sclerosis (MS) have been rarely reported and suggest the possibility of an alternative diagnosis. The aim was to describe the clinical and demographic characteristics of MS patients who debuted with atypical symptoms and to estimate the sensitivity, specificity and positive predictive value (PPV) for MS diagnosis. A retrospective analysis of clinical records was performed. The following data were recorded: patients with MS diagnosis according to current diagnostic criteria at the time of diagnosis, type of symptom at the onset, time to second relapse, presence of oligoclonal bands (OCB) in cerebrospinal fluid (CSF) and radiological red flags on MRI. A descriptive and inferential analysis was performed using the chi square test, and sensitivity, specificity and PPV were calculated. Six hundred two patients were diagnosed with MS, of which 22 (3.65%) had an atypical clinical presentation. 54.5% were women. The mean age was 29 years (SD ± 11.7). The most common atypical symptom was peripheral facial palsy (27%). The PPV for atypical onset was 6.14%; p < 0.001. Sensitivity and specificity of these symptoms to MS diagnosis were 3.65% and 19%, respectively. In our research, the presence of atypical symptoms at the onset of MS was very low. Other diseases must be excluded, taking into account their low sensitivity, specificity and PPV.

Resumen Las manifestaciones clínicas atípicas al inicio de la esclerosis múltiple (EM) son poco frecuentes y sugieren la posibilidad de un diagnóstico alternativo. El objetivo fue describir las características clínicas en la EM con síntomas atípicos al inicio, y estimar la sensibilidad, especificidad y valor predictivo posi tivo (VPP) para el diagnóstico de EM. Se trata de un análisis retrospectivo de historias clínicas. Se registraron los siguientes datos: pacientes con diagnóstico de EM acorde a los criterios diagnósticos correspondientes, tipo de síntoma de inicio, tiempo hasta la segunda recaída, presencia de bandas oligoclonales en el líquido cefalorraquídeo (LCR) y de banderas rojas radiológicas en la Resonancia Magnética de encéfalo (RMN). Se realizó un análisis descriptivo e inferencial utilizando la prueba de chi cuadrado y se calcularon la sensibilidad, la especificidad y el VPP. Seiscientos dos pacientes tuvieron un diagnóstico final de EM, de los cuales 22 (3.7%) tuvieron una presentación clínica atípica. El 54.5% eran mujeres. La edad promedio fue de 29 años (DE ± 11.7). El síntoma atípico más frecuente fue parálisis facial periférica aislada (6/22). El VPP para el inicio atípico fue de 6.1%; p < 0001. La sensibilidad y especificidad de estos síntomas al diagnóstico de EM fueron del 3.7% y 19%, respectivamente. En nuestra cohorte, demostramos que la presencia de síntomas atípicos como presentación de la EM es poco frecuente. Es mandatorio la exclusión de otras enfermedades, teniendo en cuenta su baja sensibilidad, especificidad y VPP.

Resumo O objetivo desse artigo consiste em identificar as correntes de pensamento utilizadas para a produção científica sobre conselhos e conferências de saúde, no período de 1990 a 2017. Trata-se de uma revisão integrativa de literatura realizada nas bases SciELO, LILACS e portal de periódicos da CAPES que resultou na seleção de 152 trabalhos. Estes foram analisados segundo ano de publicação, procedência institucional dos autores, veículo de divulgação, objeto e tipo de estudo e abordagem teórica. Identificou-se um aumento gradativo no número de publicações ao longo do período estudado, sendo que a maioria dos estudos com base empírica (92,8%) não explicita, nominalmente, a utilização de qualquer abordagem teórica na análise dos dados. As abordagens estruturalista, pós-estruturalista e neo-institucionalista utilizadas foram mediadas por modelo teórico, teorias de médio alcance e conceitos de autores da tradição européia, norte-americana e latino-americana. O conhecimento produzido sobre conselho e conferência de saúde no Brasil pode se beneficiar ainda mais da densidade das abordagens teóricas das ciências sociais e políticas.

Abstract This paper aimed to identify the thinking currents used for scientific production on health councils and conferences, from 1990 to 2017. This is an integrative review of literature carried out at the SciELO, LILACS and CAPES journals portals that resulted in the selection of 152 papers. They were analyzed by year of publication, author’s institutional origin, dissemination media, object and type of study and theoretical approach. We identified that a gradual increase occurred in the number of publications over the study period and most empirical studies (92.8%) do not explicitly state the use of any theoretical approach in data analysis. The structuralist, post-structuralist and neo-institutionalist approaches used were mediated by a theoretical model, medium-range theories and concepts of authors of the European, North American and Latin American traditions. The knowledge produced about health council and conference in Brazil may benefit even more from the density of theoretical approaches to social and political sciences.

Resumo O objetivo desse artigo consiste em identificar as correntes de pensamento utilizadas para a produção científica sobre conselhos e conferências de saúde, no período de 1990 a 2017. Trata-se de uma revisão integrativa de literatura realizada nas bases SciELO, LILACS e portal de periódicos da CAPES que resultou na seleção de 152 trabalhos. Estes foram analisados segundo ano de publicação, procedência institucional dos autores, veículo de divulgação, objeto e tipo de estudo e abordagem teórica. Identificou-se um aumento gradativo no número de publicações ao longo do período estudado, sendo que a maioria dos estudos com base empírica (92,8%) não explicita, nominalmente, a utilização de qualquer abordagem teórica na análise dos dados. As abordagens estruturalista, pós-estruturalista e neo-institucionalista utilizadas foram mediadas por modelo teórico, teorias de médio alcance e conceitos de autores da tradição européia, norte-americana e latino-americana. O conhecimento produzido sobre conselho e conferência de saúde no Brasil pode se beneficiar ainda mais da densidade das abordagens teóricas das ciências sociais e políticas.

Abstract This paper aimed to identify the thinking currents used for scientific production on health councils and conferences, from 1990 to 2017. This is an integrative review of literature carried out at the SciELO, LILACS and CAPES journals portals that resulted in the selection of 152 papers. They were analyzed by year of publication, author’s institutional origin, dissemination media, object and type of study and theoretical approach. We identified that a gradual increase occurred in the number of publications over the study period and most empirical studies (92.8%) do not explicitly state the use of any theoretical approach in data analysis. The structuralist, post-structuralist and neo-institutionalist approaches used were mediated by a theoretical model, medium-range theories and concepts of authors of the European, North American and Latin American traditions. The knowledge produced about health council and conference in Brazil may benefit even more from the density of theoretical approaches to social and political sciences.

Abstract: A randomized controlled parallel clinical trial was conducted to evaluate the efficacy of the association of 1.23% topical professional acidulated phosphate fluoride (APF) gel with oral hygiene and dietary instructions on the arrest of active non-cavitated lesions in permanent, mixed, and temporary dentition in children between 3 and 12 years of age. Ninety-eight caries-active children were randomly divided into two groups: a fluoride gel group (n = 49) and a non-fluoridated gel group (n = 49). Each group received up to eight weekly applications of gel, weekly professional toothbrushing with oral hygiene instructions and dietary counselling. Caries lesions were assessed qualitatively through visual-tactile criteria performed in three stages: initial, intermediate, and final. Regression models were applied to identify risk indicators for caries control. Between-group comparison regarding the time taken to arrest the lesions was performed using Chi-squared and Fisher's exact tests. Seventeen children did not receive the allocated intervention, and one was lost to follow-up (n = 80). There was no difference between the control and placebo groups regarding the time to the arrest of the lesion (p >.05). The treatments showed similar results without significant statistical difference (p = 0.33; 95%CI: 0.32–1.48). No adverse effects were observed. It can be concluded that no additional effect of the association of 1.23% APF gel with oral hygiene using fluoride dentifrice and dietary instructions on the arrest of active non-cavitated lesions could be established. We can also confirm the importance of toothbrushing frequency and, consequently, the visible plaque reduction in the control of caries activity. RBR-37V5S3

Resumo Este trabalho tem por objetivo discutir a concepção de atingidos e a da reconfiguração do território e das vidas sociais com a observação e análise de duas comunidades não consideradas afetadas pela UHE Jirau: a do pequeno vilarejo Jirau e Vila da Penha. A pesquisa se caracteriza como teórico-descritiva, a partir das questões relacionadas ao território de ocorrência de impactos da construção e da operação das hidrelétricas, e fora realizado trabalho de campo com observação não participante, os dados foram compilados a partir da percepção dos pesquisadores e possibilitam concluir que os danos da construção da UHE, nessas comunidades colocam-nas em condição de atingidos, o impacto acontece no território como resultado da influência e da confluência das redes de vida vivida, compreendendo o rio e o que o relaciona, as estradas de conexão, as redes de moradia, além dos espaços de fuga ou refúgio.

Abstract This work seeks to discuss the conception of affected and the reconfiguration of the territory and social lives with the observation and analysis of two communities not considered affected by the Jirau HPP: that of the small Village Jirau and Village of the Penha. The research is characterized as theoretical-descriptive, based on the issues related to the territory of occurrence of impacts of the construction and operation of hydroelectric plants, and fieldwork was performed with non-participant observation, the data were compiled from the perception of the researchers and allow us to conclude that the damage of the construction of the HPP, in these communities, put them in a condition of being affected , the impact happens in the territory as a result of the influence and confluence of the networks of life lived, comprising the river and what relates it, the connecting roads, the networks of housing.

Resumen Este trabajo tiene como objetivo discutir la concepción de los afectados por hidroeléctricas, y la reconfiguración de su territorio y vida social por medio de la observación y análisis de dos comunidades consideradas no afectadas por el Complejo Hidroeléctrico (CH) de Jirau: la pequeña aldea Jirau y Vila da Penha. Esta investigación se define como teórico-descriptiva y se basa en las cuestiones relacionadas al territorio de ocurrencia de impactos de la construcción y operación de planos hidroeléctricos. El trabajo de campo se realizó con observación no participante. Los datos fueron compilados desde la percepción de los investigadores y nos permiten concluir que el daño de la construcción del CH en estas comunidades de hecho las puso en condición de afectadas. El impacto en el territorio es resultado de la influencia y confluencia de las redes de vida vivida, que comprenden el río y todo lo que se relaciona con él, como los caminos de conexión, las redes de viviendas, bien como los espacios de fuga o refugio.

Resumo: Objetivo: O presente estudo objetiva descrever a produção do conhecimento da enfermagem sobre atenção à saúde da população indígena Brasileira. Método: Realizou-se uma scoping review nas bases LILACS, IBECS, MEDLINE, SCOPUS, SciELO, BDENF, BTDB, Portal de Periódicos da CAPES e google acadêmico, em janeiro e fevereiro de 2020. Incluíram-se artigos originais, teses e dissertações. A revisão abrangeu 16 estudos publicados entre 2010 e 2018. Resultados: Da análise, resultaram duas categorias: as ações de enfermagem no cuidado a população indígena Brasileira e as modalidades assistenciais que são utilizadas pela enfermagem no cuidado a população indígena. Conclusão: Conclui-se que os resultados desta revisão podem ser úteis para os enfermeiros que atuam no cuidado a população indígena, os quais precisam estar preparados e sensibilizados para os desafios que incluem trabalhar com essa população.

Abstract: Objective: This study aims to describe the production of nursing knowledge about health care for the Brazilian indigenous population. Method: A scoping review was carried out in the LILACS, IBECS, MEDLINE, SCOPUS, SciELO, BDENF, BTDB, CAPES Journal Portal and google scholar databases in January and February 2020. Original articles, theses and dissertations were included. The review covered 16 studies published between 2010 and 2018. Results: The analysis resulted in two categories: nursing actions in the care of the Brazilian indigenous population and care modalities that are used by nursing in the care provided to the indigenous population. Conclusion: It is concluded that the results of this review can be useful for nurses who work in the care of the indigenous population, who need to be prepared and sensitized to the challenges that include working with this population.

Resumen: Objetivo: Este estudio tiene como objetivo describir la producción de conocimientos de enfermería sobre el cuidado de la salud para la población indígena brasileña. Método: Se realizó una revisión de alcance en LILACS, IBECS, MEDLINE, SCOPUS, SciELO, BDENF, BTDB, CAPES Journals Portal y google scholar, en enero y febrero de 2020. Se incluyeron artículos originales, tesis y disertaciones. La revisión abarcó 16 estudios publicados entre 2010 y 2018. Resultados: Del análisis, resultaron dos categorías: las acciones de enfermería en el cuidado de la población indígena brasileña y las modalidades de atención que utiliza la enfermería en el cuidado de la población indígena. Conclusión: Se concluye que los resultados de esta revisión pueden ser de utilidad para los enfermeros que laboran en el cuidado de la población indígena, quienes necesitan estar preparados y conscientes de los desafíos que conlleva trabajar con esta población.

Abstract: In this paper1, we investigate the level of vocabulary knowledge and the lexical-integration ability of good and poor comprehenders at the 8th grade of Elementary School. The participants were assessed in the following tasks: reading comprehension, listening comprehension, decoding, vocabulary, lexical-semantic integration and incongruence detection. The performance comparison revealed that good comprehenders performed significantly better than poor comprehenders in the measures of vocabulary and integration. The difference in the accuracy of the integration tasks remained significant after controlling for word knowledge. The results suggest that good and poor comprehenders differentiate not only in lexical semantic knowledge but also in lexical-semantic processing.

Resumo Os homicídios no Brasil são um dos indicadores mais sensíveis da desigualdade social nas cidades. Assim, políticas de proteção social integradas nos territórios podem impactar esse evento em saúde. Este artigo objetiva descrever os homicídios em Belo Horizonte à luz de um modelo conceitual, parte de um processo avaliativo de um projeto de reurbanização na cidade. A partir da revisão da literatura, construiu-se um modelo conceitual para a compreensão dos homicídios e sua vinculação com o viver nas cidades. Realizou-se um estudo descritivo dos homicídios a partir de dados do Sistema de Informação sobre Mortalidade (SIM) relativos ao período de 2002 a 2012. O modelo conceitual reforça que os homicídios encontram nas cidades seus mais expressivos determinantes vinculados à desigualdade e à exclusão, junto a valores de uma cultura de força e preconceitos. Os homicídios em Belo Horizonte apresentam taxas elevadas na cidade formal, sendo de três a seis vezes maiores nas favelas. Morrem mais negros, jovens homens, de baixa escolaridade, nas vias públicas e nos territórios vulneráveis. Os homicídios são a síntese das desvantagens urbanas, especialmente em tais áreas. Retrata-se em Belo Horizonte o que se vê no Brasil, denunciando a desigualdade e sua perversidade no viver e morrer nas cidades.

Abstract In Brazil, homicides are one of the most sensitive indicators of urban social inequalities. Integrated social protection policies can have a definite impact over this health event. The objective of this article is to describe homicides in Belo Horizonte in the light of a conceptual model, part of the evaluation process of a redevelopment project in the city. Based on a review of the literature, this conceptual model was constructed to assess the relationship between homicides and urban living in Brazil. A descriptive study of homicides was carried out using data on the period from 2002 to 2012, extracted from the Mortality Information System (Sistema de Informações sobre Mortalidade - SIM). The conceptual model reinforces that the most expressive determinants of homicides are found in the cities, and are linked to inequality and exclusion, together with the values of a culture based on prejudice and the use of force. The prevalence of homicides in Belo Horizonte was high even in the formally urbanized part of the city, but reached numbers three to six times higher in its favelas. Most deaths pertain black young men of low schooling. These deaths usually take place in public roads and in vulnerable territories. Homicides are the synthesis of urban disadvantages, especially in vulnerable areas. The situation in Belo Horizonte is similar throughout the rest of Brazil. Pointing to the reality of living and dying in cities, these data testify against social inequality and its perversity.

Resumo O objetivo deste artigo é analisar a participação do Conselho Nacional na construção e realização da 15ª Conferência Nacional de Saúde (CNS), bem como os principais componentes desse evento, o desenho institucional, no que se refere a sua dinâmica participativa, e as propostas e diretrizes aprovadas, e relacionar esse fenômeno político à conjuntura brasileira. Este estudo de caso sobre a 15ª CNS teve como fonte de produção de dados entrevistas com 27 conselheiros nacionais e a revisão documental de atas, notícias e outras fontes do Conselho relacionadas à 15ª Conferência. O Conselho Nacional desenvolveu estratégias para politizar a elaboração das diretrizes e intensificou a participação da sociedade por meio das conferências livres. O debate em torno da saúde em 2015 envolveu milhares de pessoas no país - afinal, foram realizadas 4.706 conferências municipais, 26 estaduais, a conferência distrital e a nacional. As principais pautas da 15ª Conferência foram a defesa da democracia e o financiamento público da saúde. A 15ª CNS ainda prevaleceu com o formato burocrático. Além das inovações na forma das conferências, é necessário ampliar a permeabilidade dos tomadores de decisão à participação social e democratizar o processo de planejamento e a gestão em saúde.

Abstract This article aims to analyze the participation of the National Council in the construction and realization of the 15th National Health Conference (CNS), as well as the main components of this event, the institutional design regarding its participatory dynamics, and the approved proposals and guidelines, relating this political phenomenon to the Brazilian context. This case study on the 15th CNS had, as data sources, the interviews with 27 national counselors and the documentary review of minutes, news and other sources of the Council related to the 15th Conference. The National Council developed strategies to politicize the elaboration of guidelines and intensified society participation through free conferences. The Health debate in 2015 involved thousands of people in the country - after all, 4,706 municipal and 26 state, district and national conferences were held. The main agendas of the 15th Conference were the defense of democracy and the public financing of health. Nonetheless, the bureaucratic format still prevailed in the 15th CNS. In addition to innovations in the form of conferences, one must increase the permeability of decision-makers to social participation and democratize the health planning and management process.

Resumo Os homicídios no Brasil são um dos indicadores mais sensíveis da desigualdade social nas cidades. Assim, políticas de proteção social integradas nos territórios podem impactar esse evento em saúde. Este artigo objetiva descrever os homicídios em Belo Horizonte à luz de um modelo conceitual, parte de um processo avaliativo de um projeto de reurbanização na cidade. A partir da revisão da literatura, construiu-se um modelo conceitual para a compreensão dos homicídios e sua vinculação com o viver nas cidades. Realizou-se um estudo descritivo dos homicídios a partir de dados do Sistema de Informação sobre Mortalidade (SIM) relativos ao período de 2002 a 2012. O modelo conceitual reforça que os homicídios encontram nas cidades seus mais expressivos determinantes vinculados à desigualdade e à exclusão, junto a valores de uma cultura de força e preconceitos. Os homicídios em Belo Horizonte apresentam taxas elevadas na cidade formal, sendo de três a seis vezes maiores nas favelas. Morrem mais negros, jovens homens, de baixa escolaridade, nas vias públicas e nos territórios vulneráveis. Os homicídios são a síntese das desvantagens urbanas, especialmente em tais áreas. Retrata-se em Belo Horizonte o que se vê no Brasil, denunciando a desigualdade e sua perversidade no viver e morrer nas cidades.

Abstract In Brazil, homicides are one of the most sensitive indicators of urban social inequalities. Integrated social protection policies can have a definite impact over this health event. The objective of this article is to describe homicides in Belo Horizonte in the light of a conceptual model, part of the evaluation process of a redevelopment project in the city. Based on a review of the literature, this conceptual model was constructed to assess the relationship between homicides and urban living in Brazil. A descriptive study of homicides was carried out using data on the period from 2002 to 2012, extracted from the Mortality Information System (Sistema de Informações sobre Mortalidade - SIM). The conceptual model reinforces that the most expressive determinants of homicides are found in the cities, and are linked to inequality and exclusion, together with the values of a culture based on prejudice and the use of force. The prevalence of homicides in Belo Horizonte was high even in the formally urbanized part of the city, but reached numbers three to six times higher in its favelas. Most deaths pertain black young men of low schooling. These deaths usually take place in public roads and in vulnerable territories. Homicides are the synthesis of urban disadvantages, especially in vulnerable areas. The situation in Belo Horizonte is similar throughout the rest of Brazil. Pointing to the reality of living and dying in cities, these data testify against social inequality and its perversity.