ABSTRACT This work aimed at investigating the viability of near infrared spectrometry (NIR), associated with chemometric methods, in order to identify differences at the levels of vigor of naturally and artificially aged soybean seeds. Seeds of six soybean genotypes were analyzed when freshly harvested, after natural aging in storage for eight months, and after artificial aging at the temperature of 41 °C for 96 hours. The seed moisture content, germination potential and vigor were evaluated. Also, there were measured the content of protein, oil and of the fatty acids: palmitic, stearic, oleic, linoleic and linolenic. The NIR spectra were obtained from the freeze-dried and grinded seeds. The natural and artificial aging of the seeds promote deterioration at distinct levels, reflecting in differences in seed vigor. The regions of the electromagnetic spectrum between wavelengths of 1000-1200 nm, 1350-1450 nm, 1800-1900 nm and 2300-2400 nm are important to distinguish the levels of quality of the soybean seeds. The contents of oil and protein have a relationship with the physiological quality of the seeds. Also, the most relevant wavelengths for the classification of seed vigor present a relationship with these compounds. NIR spectroscopy, in combination with chemometric methods, presents potential to be used in the classification of soybean seeds regarding their physiological quality. NIR, , (NIR) methods harvested months 4 C 9 hours evaluated Also acids palmitic stearic oleic linolenic freezedried freeze dried 10001200 1000 1200 1000-120 13501450 1350 1450 1350-145 18001900 1800 1900 1800-190 23002400 2300 2400 2300-240 compounds spectroscopy (NIR 1000120 100 120 1000-12 1350145 135 145 1350-14 1800190 180 190 1800-19 2300240 230 240 2300-24 100012 10 12 1000-1 135014 13 14 1350-1 180019 18 19 1800-1 230024 23 24 2300-2 10001 1 1000- 13501 1350- 18001 1800- 23002 2 2300-

BACKGROUND Leishmania tarentolae is a non-pathogenic species found in lizards representing an important model for Leishmania biology. However, several aspects of this Sauroleishmania remain unknown to explain its low level of virulence. OBJECTIVES We reported several aspects of L. tarentolae biology including glycoconjugates, proteolytic activities and metabolome composition in comparison to pathogenic species (Leishmania amazonensis, Leishmania braziliensis, Leishmania infantum and Leishmania major). METHODS Parasites were cultured for extraction and purification of lipophosphoglycan (LPG), immunofluorescence probing with anti-gp63 and resistance against complement. Parasite extracts were also tested for proteases activity and metabolome composition. FINDINGS Leishmania tarentolae does not express LPG on its surface. It expresses gp63 at lower levels compared to pathogenic species and, is highly sensitive to complement-mediated lysis. This species also lacks intracellular/extracellular activities of proteolytic enzymes. It has metabolic differences with pathogenic species, exhibiting a lower abundance of metabolites including ABC transporters, biosynthesis of unsaturated fatty acids and steroids, TCA cycle, glycine/serine/threonine metabolism, glyoxylate/dicarboxylate metabolism and pentose-phosphate pathways. MAIN CONCLUSIONS The non-pathogenic phenotype of L. tarentolae is associated with alterations in several biochemical and molecular features. This reinforces the need of comparative studies between pathogenic and non-pathogenic species to elucidate the molecular mechanisms of virulence during host-parasite interactions. nonpathogenic non However L glycoconjugates amazonensis braziliensis major. major . major) LPG, , (LPG) antigp63 antigp anti gp anti-gp6 complement surface gp6 complementmediated mediated lysis intracellularextracellular intracellular extracellular enzymes transporters steroids cycle glycineserinethreonine glycine serine threonine glyoxylatedicarboxylate glyoxylate dicarboxylate pentosephosphate pentose phosphate pathways features hostparasite host parasite interactions (LPG antigp6 anti-gp

Abstract Background It is justified by the high population’s morbidity and mortality rate, as well as the increasing present use of nanoparticles in this pathological context. Objectives To describe the main nanotechnology breakthroughs in the field of cardiovascular disease (CVD) and disseminate pertinent information in the literature. Methods This is a systematic review conducted between September and October 2021. The review was carried out through basic nature, following the initial script for the selective reading of articles in chronological order to collect relevant and consistent data related to the theme. Results It is evidenced the main advances of nanotechnology in the field of CVDs, namely, acute coronary syndromes (ACSs), heart failure (HF), and systemic arterial hypertension (SAH). Conclusion The importance of further and deeper studies in this area is emphasized, in order to make the already approved treatments feasible, so they can reach all publics at a low cost. populations population s rate context CVD (CVD literature 2021 nature theme CVDs namely ACSs, ACSs , (ACSs) HF, HF (HF) SAH. SAH . (SAH) emphasized feasible cost 202 (ACSs (HF (SAH 20 2

ABSTRACT The Scientists of Tomorrow/ Cientistas do Amanhã project is an immersive science training program developed by the Program of Post-Graduation in Health Sciences at Hospital Israelita Albert Einstein. This program was conducted in partnership with Volunteering and Escola Municipal de Ensino Fundamental Professor Paulo Freire in Paraisópolis, São Paulo, Brazil. The Scientists of Tomorrow Program comprised a short training period conducted in May 2022 involving 37 students, and a long training period from August to December 2022, which included 15 students. It aimed to popularize science through practical activities; transfer knowledge to young students; sensitize and guide them to pursue academic-scientific careers; reduce stereotypes about scientific work and scientists; and help students understand the social, political, and ethical roles of science within society. All activities were led by postgraduate students and professors from our postgraduate program, physicians, nurses, physiotherapists, biomedicals, and veterinarians from Hospital Israelita Albert Einstein, as well as medical students from Faculdade Israelita de Ciências da Saúde Albert Einstein . Activities in the short training included lectures on cinema and science, strategies to combat fake news, non-violent communication, innovation, design-thinking framework, and developing a scientific project. During the long training period, discussions were focused on nanotechnology, animal research, big data, bioinformatics, meditation, blood and bone marrow donation, telemedicine, sex and sexually-transmitted infections, rehabilitation, career opportunities, and scientific integrity. In addition, practical activities were further expanded using optical and confocal microscopy, cytometry, and basic concepts regarding the structure and function of living cells. The program also included the launching of the open-air outreach Education E-natureza activity, which turned students into ambassadors of nature. In conclusion, the Scientists of Tomorrow Program was innovative and enabled young students to learn that science is a collective activity that can enhance public health. PostGraduation Post Graduation Paraisópolis Brazil 202 3 1 academicscientific academic careers scientists social political society physicians nurses physiotherapists biomedicals news nonviolent non violent communication innovation designthinking design thinking framework nanotechnology research data bioinformatics meditation donation telemedicine sexuallytransmitted sexually transmitted infections rehabilitation opportunities integrity addition microscopy cytometry cells openair open air Enatureza E natureza nature conclusion health 20 2

ABSTRACT Variation in rainfall affects crops; therefore, agricultural practices become essential for forage production in semi-arid regions. This study aimed to evaluate the influence of different agricultural practices on phyllochron, structural characteristics of forage cactus and millet, and their relations with crop yield using the principal component analysis (PCA). The design was in randomized blocks, with six treatments: sole cropped cactus without straw mulching, sole cropped cactus with straw mulching, sole cropped millet without straw mulching, sole cropped millet with straw mulching, and cactus intercropping with millet, with and without straw mulching, each with four replicates. There were three cactus cycles and nine millet cycles (three cycles of cultivars BRS1501 and six of IPA Bulk-1-BF). Biometric parameters were evaluated monthly, while yield was determined after the crop harvest. Phyllochron was determined with the regression analysis. The PCA was applied to structural characteristics and yield. The systems adopted did not influence the structural characteristics of cactus and millet ( p > 0.05), except for cladode thickness, which increased with straw mulching. Phyllochron of the millet reduced when the crop was intercropped. The structural characteristics of cladode length, width, and thickness influenced crop yield, mainly in systems with straw mulching. Straw mulching and intercropping alter phyllochron of cactus and millet. The adoption of straw mulching has a more significant relationship with cactus yield, whereas biometric variables influence crop yield for millet, not the cropping system. crops therefore semiarid semi arid regions PCA. . (PCA) blocks treatments replicates BRS BRS150 Bulk1BF. Bulk1BF BulkBF Bulk 1 BF Bulk-1-BF) monthly harvest 0.05, 005 0.05 , 0 05 0.05) intercropped length width system (PCA BRS15 Bulk-1-BF 00 0.0 BRS1 0.

Resumo A NBR 7190 (ABNT, 1997) assume o valor médio do módulo de elasticidade à compressão na direção paralela às fibras (Ec0,m) como o representativo de todas as barras de estruturas. Devido à variabilidade da madeira, tal metodologia pode resultar em valores de deslocamento superiores ao limite definido pela norma, o que pode gerar patologias na estrutura. Buscando avaliar a influência da adoção do Ec0,m no cálculo das flechas, foram realizados ensaios experimentais para obter as propriedades mecânicas da madeira branquilho. Com o auxílio de simulações numéricas e de valores experimentais, foram analisadas três tipologias (fink, bowstring e banzos paralelos) e dois vãos (10 m e 20 m). Adotando o Ec0,m, foram determinadas as cargas máximas para o deslocamento de L/200. Posteriormente, utilizando o mesmo carregamento, foram atribuídos valores aleatórios de rigidez para cada elemento da treliça, medindo o deslocamento máximo de cada modelo. Em modelos para os quais o módulo de elasticidade foi atribuído aleatoriamente, foram observadas flechas superiores em aproximadamente 28% e 32% para vãos de 10 m e de 20 m respectivamente. Isso pode justificar algumas patologias que podem ser evitadas com a pré-classificação não destrutiva e a colocação racional das peças em regiões mais solicitadas.

Abstract The NBR 7190 (ABNT, 1997) assumes the mean value of the elasticity module to compression in the direction parallel to grain (E c0,m ) as being the representative for all roof structure bars. Due to the variability of woods, such methodology can result in displacement values higher than the limit defined by the standard, which can generate pathologies in the structure. In order to evaluate the influence of the use of E c0,m on the displacement calculation, experimental tests were carried out to obtain the mechanical properties of the wood species Sebastianiacommersoniana (Baillon) Smith & Downs. With the aid of numerical simulations and experimental values, three typologies (fink, bowstring and parallel chord) and two spans (10 m and 20 m) were analysed. Adopting E c0,m , the maximum loads for a displacement of L/200 were determined. After, random stiffness values were assigned to each element of the truss, measuring the maximum displacement of each model. In models where the modulus of elasticity was randomly assigned, superior arrows were observed in approximately 28% and 32% for spans of 10 m and 20 m, respectively. It may explain some pathologies that can be avoided with non-destructive pre-classification and the rational placement of parts in the most vulnerable areas.

Resumo Esta pesquisa busca analisar o conhecimento dos moradores sobre o território, Complexo Industrial e Portuário do Pecém (CIPP), qualidade de vida das comunidades que vivem no entorno dos empreendimentos, além da prevalência de hipertensão e excesso de peso. Trata-se de um inquérito epidemiológico, de base domiciliar, envolvendo quatro áreas da Estratégia de Saúde da Família (ESF) do Município de São Gonçalo do Amarante e uma de Caucaia, Ceará, Brasil. O estudo foi realizado entre 10/2017 e 03/2018, em que foram realizadas aferições antropométricas e pressão arterial e coletados dados sociodemográficos e o conhecimento sobre comunidade, CIPP e qualidade de vida. Dos 503 adultos entrevistados, 69,8% eram do sexo feminino e a média de idade foi 44 anos. Parada foi a área que relatou o maior percentual de problemas relacionados às partículas aéreas (51,1%), pior conceito em relação ao CIPP (40,1% ruim), maior percentual de piora da qualidade de vida (29,1%) e maior desejo de mudar (31,5%). Pecém apresentou maior percentual de problemas na comunidade relacionados à violência, consumo de drogas ilícitas e prostituição. Conclui-se que se apresenta indícios de impacto na saúde e qualidade de vida das populações locais sem maiores benefícios diretos no trabalho/renda.

Abstract This research aimed to analyze the dwellers’ knowledge of the territories, Pecém Port and Industrial Compound (CIPP), the quality of life of the communities living in the vicinity of the enterprises, and the prevalence of hypertension and overweight. This is a home-based, epidemiological survey of four areas of the Family Health Strategy (ESF) in São Gonçalo do Amarante and one area of the ESF in Caucaia, Ceará, Brazil. The study was carried out between 10/2017 and 03/2018. Anthropometric and blood pressure measurements were performed, and sociodemographic data and knowledge about community, the CIPP, and quality of life were collected. A total of 69.8% of the 503 adults interviewed were female, and the mean age was 44 years. Parada was the area reporting the highest percentage of problems related to air particles (51.1%), the worst concept regarding the CIPP (40.1% bad), the highest percentage of worse quality of life (29, 1%), and greater desire to move to another place (31.5%). Pecém had the highest percentage of community problems related to violence, consumption of illicit drugs, and prostitution. We concluded that there are signs of impact on local populations’ health and quality of life without more significant direct work/income benefits.

Resumo Esta pesquisa busca analisar o conhecimento dos moradores sobre o território, Complexo Industrial e Portuário do Pecém (CIPP), qualidade de vida das comunidades que vivem no entorno dos empreendimentos, além da prevalência de hipertensão e excesso de peso. Trata-se de um inquérito epidemiológico, de base domiciliar, envolvendo quatro áreas da Estratégia de Saúde da Família (ESF) do Município de São Gonçalo do Amarante e uma de Caucaia, Ceará, Brasil. O estudo foi realizado entre 10/2017 e 03/2018, em que foram realizadas aferições antropométricas e pressão arterial e coletados dados sociodemográficos e o conhecimento sobre comunidade, CIPP e qualidade de vida. Dos 503 adultos entrevistados, 69,8% eram do sexo feminino e a média de idade foi 44 anos. Parada foi a área que relatou o maior percentual de problemas relacionados às partículas aéreas (51,1%), pior conceito em relação ao CIPP (40,1% ruim), maior percentual de piora da qualidade de vida (29,1%) e maior desejo de mudar (31,5%). Pecém apresentou maior percentual de problemas na comunidade relacionados à violência, consumo de drogas ilícitas e prostituição. Conclui-se que se apresenta indícios de impacto na saúde e qualidade de vida das populações locais sem maiores benefícios diretos no trabalho/renda.

Abstract This research aimed to analyze the dwellers’ knowledge of the territories, Pecém Port and Industrial Compound (CIPP), the quality of life of the communities living in the vicinity of the enterprises, and the prevalence of hypertension and overweight. This is a home-based, epidemiological survey of four areas of the Family Health Strategy (ESF) in São Gonçalo do Amarante and one area of the ESF in Caucaia, Ceará, Brazil. The study was carried out between 10/2017 and 03/2018. Anthropometric and blood pressure measurements were performed, and sociodemographic data and knowledge about community, the CIPP, and quality of life were collected. A total of 69.8% of the 503 adults interviewed were female, and the mean age was 44 years. Parada was the area reporting the highest percentage of problems related to air particles (51.1%), the worst concept regarding the CIPP (40.1% bad), the highest percentage of worse quality of life (29, 1%), and greater desire to move to another place (31.5%). Pecém had the highest percentage of community problems related to violence, consumption of illicit drugs, and prostitution. We concluded that there are signs of impact on local populations’ health and quality of life without more significant direct work/income benefits.

Abstract The vegetation structure is a good indicator of the conservation condition of an ecosystem, since it reflects alterations caused by anthropic action. This study proposes to analyze the phytosociological aspects of the Caatinga domain under anthropic disturbance and their correlations with hydrological variables. Twenty-five 400 m 2 plots were sampled in the municipality of Floresta - PE, Brazil. Phytosociological parameters such as density, frequency and dominance were calculated. The seasonality of plant area index was analyzed for six species. The association between structural characteristics and hydrological variables (throughfall, stemflow and interception loss) in the species was evaluated by multivariate analysis. A total of 930 individuals, six families and 10 species were recorded. The abundance of the species Cenostigma pyramidale in the area may be an indicator of the degree of change in the vegetation. The structural characteristics of the species revealed little association with rainfall partitioning.

Resumo Regiões semiáridas são caracterizadas pela elevada evapotranspiração e baixa precipitação pluvial, favorecendo o acúmulo de sais quando irrigado com água salobra. Objetivouse avaliar o efeito do cultivo de milheto com níveis de água salobra e fertilização orgânica nas propriedades químicas e físicas do solo. Adotou-se o delineamento de blocos ao acaso, com arranjo fatorial, em parcelas subdivididas, com três repetições. As parcelas foram constituídas por quatro lâminas de irrigação (25, 50, 75 e 100% da evapotranspiração da cultura) e as subparcelas foram compostas por quatro níveis de fertilização orgânica (0; 15; 30 e 45 Mg ha-1). No final do ciclo de produção do milheto, o solo foi coletado nas camadas de 0-0.20 e 0.20-0.40 m, para aspectos físicos (densidade do solo, densidade de partículas e porosidade) e químicos (CE, pH, K, Na, Ca, Mg, H + Al, SB, CTC, V). Não houve interação entre a água salobra e a fertilização orgânica nas propriedades químicas do solo. A água salobra reduziu o potássio na camada de 0,20-0,.40 m. Observou-se efeito linear negativo para densidade na camada 0,20 - 0,40 m sob níveis de fertilização orgânica. Níveis de água salobra e fertilizante orgânico no cultivo do milheto não altera as propriedades químicas e físicas do solo na camada de 0-0,20 m. Porém, o uso de água salobra reduz a concentração de potássio no solo e a aplicação de fertilização orgânica reduz a densidade do solo na camada de 0.20-0,40 m.

Abstract Semi-arid regions are characterized by high evapotranspiration and low rainfall, favoring the accumulation of salts when irrigated with brackish water. The aim of this study was to evaluate the effect of pearl millet cultivation with brackish water levels and fertilized with organic fertilizer on the chemical and physical properties of the soil. A split plot randomized block design was adopted, in a factorial arrangement, with three repetitions. Plots consisted of four irrigation levels (25, 50, 75 and 100% crop evapotranspiration) and subplots consisted of four levels of organic fertilizer (0; 15; 30 and 45 Mg ha-1). At the end of the pearl millet production cycle, soil was collected from layers 0-0.20 m and 0.20-0.40 m, for physical (soil bulk density, particle density and porosity) and chemical (EC, pH, K, Na, Ca, Mg, H + Al, SB, CEC, V) properties. There was no effect of interaction of brackish water levels and organic fertilizer levels on soil chemical properties. Brackish water reduced potassium on layer 0.20-0.40 m. A negative linear effect was found for density in the 0.20-0.40 m layer under different levels of organic fertilizer. Brackish water levels and organic fertilizer levels in the cultivation of pearl millet does not alter soil chemical and physical properties at the 0-0.20 m layer. However, the use of brackish water reduces the concentration of potassium in the soil and the application of organic fertilizer reduces soil density at the 0.20-0.40 m layer.

ABSTRACT It was evaluated how straw management modifies the development, growth, nutrient cycling and crop water productivity of sugarcane in the semiarid region of Brazil. The experiment was carried out using two plots with 5 ha each, being one without straw on the soil surface and one with 26 Mg·ha-1 covering the soil. Sugarcane growth and development and straw decomposition coefficient were evaluated, whereas the industrial yield, juice quality, dry matter partitioning, and crop water productivity were determined at harvesting. The straw decomposition coefficient was 0.0049 Mg·ha-1·day-1, and the remaining dry mass was equal to 24%. The straw affected the sugarcane growth and development until the first 100 days. The individual internode volume can be adopted as an indicator of the effect of straw on sugarcane growth because the internode volumes up to the sixth position in the with-straw treatment crop were lower than in the no-straw treatment, which was not observed in other variables of the stalks. Keeping straw on the soil surface reduced the crop lodging. Yield and juice quality were not affected, but crop water productivity was increased by keeping sugarcane straw in the field.

ABSTRACT Objective: to know and reflect on the best practices in nursing and their interface with the Expanded Family Health and Basic Healthcare Centers (NASF-AB). Method: this is a participatory research based on Paulo Freire’s methodological framework and developed from thematic investigation, coding, decoding, and critical unveiling. The information was produced and analyzed in four Culture Circles, with an average of five nurses and duration of two hours each, between April and June 2018. The investigation revealed four generating themes, unveiled during the meetings. In this study, the theme “best nursing practices that favor relations with NASF-AB” will be discussed. Results: nurses acknowledge communication as a tool that promotes best practices in nursing. It was possible to deepen the dialogue and knowledge about NASF-AB’s work process and the role of nursing. Nurses act as a link between the support team and the Family Health team, a skill resulting from their training focused on management, having leadership and dialogue as resources for conflict resolution. Conclusion: the present study contributed to improve nurses’ thinking and acting in relation to the proposed theme. The reflections made during Culture Circles boosted transformative attitudes in the practice settings. Nurse approximation with NASF-AB favors autonomy and collaborative practices (understood as best practices), encouraging interprofessional and solve-problem actions within Basic Care.

RESUMEN Objetivo: conocer y reflexionar sobre las mejores prácticas en enfermería y su interfaz con el Núcleo Extendido de Salud de la Familia y Atención Primaria (NASF-AB). Método: investigación participativa basada en el marco metodológico de Paulo Freire y desarrollada a partir de las etapas de investigación temática, codificación, decodificación y develación crítica. La información fue producida y analizada en cuatro Círculos de Cultura, con un promedio de cinco enfermeros y una duración de dos horas cada uno, entre abril y junio de 2018. La investigación reveló cuatro temas generadores, develados durante los encuentros. En este estudio se discutirá el tema: mejores prácticas de enfermería que favorecen las relaciones con la NASF-AB. Resultados: las enfermeras reconocen la comunicación como una herramienta que promueve las mejores prácticas en esta interfaz. Se logró profundizar el diálogo y el conocimiento sobre el tema, sobre el proceso de trabajo NASF-AB y el papel de la enfermería en este contexto. Se perciben a sí mismos como un vínculo entre el equipo de apoyo y el equipo de Salud de la Familia, habilidad resultante de su formación enfocada al ejercicio de la gestión y al liderazgo y al diálogo como recursos para la resolución de conflictos. Conclusión: el estudio contribuyó a la mejora del pensamiento y la actuación de los enfermeros en relación con el tema propuesto, ya que las reflexiones realizadas durante los Círculos Culturales estimularon actitudes transformadoras en los escenarios de práctica. Se observa que la aproximación de enfermeras con la NASF-AB favorece la autonomía y las prácticas colaborativas (entendidas como mejores prácticas), estimulando movimientos interprofesionales y resolutivos en el ámbito de la Atención Primaria.

RESUMO Objetivo: conhecer e refletir sobre as melhores práticas em enfermagem e sua interface com o Núcleo Ampliado de Saúde da Família e Atenção Básica. Método: pesquisa participante pautada no referencial metodológico de Paulo Freire e desenvolvida a partir das etapas de investigação temática, codificação, decodificação e desvelamento crítico. As informações foram produzidas e analisadas em quatro Círculos de Cultura, com média de cinco enfermeiras e duração de duas horas cada, entre abril e junho de 2018. A investigação revelou quatro temas geradores, desvelados durante os encontros. Neste estudo será discutido o tema: melhores práticas de enfermagem que favorecem as relações com o Núcleo Ampliado. Resultados: as enfermeiras reconhecem a comunicação como ferramenta que promove as melhores práticas nessa interface. Foi possível aprofundar o diálogo e o conhecimento sobre o tema, sobre o processo de trabalho do Núcleo e o papel da enfermagem nesse contexto. Elas se percebem como elo entre a equipe apoiadora a equipe de Saúde da Família, habilidade decorrente da sua formação voltada para o exercício da gestão e tendo a liderança e o diálogo como recursos para a resolução de conflitos. Conclusão: o estudo contribuiu para o aprimoramento do pensar e do agir das enfermeiras em relação ao tema proposto, pois as reflexões tecidas durante os Círculos impulsionaram atitudes transformadoras nos cenários de prática. Nota-se que a aproximação das enfermeiras com os Núcleos favorece a autonomia e as práticas colaborativas (compreendidas como melhores práticas), estimulando movimentos interprofissionais e resolutivos no âmbito da Atenção Primária.

RESUMO Introdução: Estudos recentes sobre o perfil das nomeações de ministros em nível federal têm mostrado maior complexidade das lógicas subjacentes a esta decisão e, como consequência, a insuficiência explicativa da dicotomia entre nomeações “técnicas” versus “políticas”. Por outro lado, pouco se conhece ainda sobre os tipos de nomeação para o secretariado de primeiro escalão nos Executivos estaduais. A partir de um estudo de caso, comparamos se as lógicas de nomeações são similares ou distintas daquelas encontradas em nível federal. Materiais e Métodos: A partir da sistematização dos dados biográficos dos secretários nomeados entre 1995 e 2015 no Rio Grande do Norte, no Brasil (RN), foi possível ir além de informações básicas (tais como: formação educacional, ocupação profissional ou filiação partidária) dos secretários, identificando as trajetórias dos indivíduos nos contextos políticos e eleitorais do estado. Propomos, a partir daí, uma tipologia para mensurar competências técnica e política. Resultados: A análise das nomeações para o caso do RN com base nessa tipologia revela que há especificidades locais que explicam parte significativa das escolhas feitas pelos governadores na montagem do seu gabinete. O tipo de nomeação mais frequente é o de uma secretária ou secretário com um perfil misto, técnico e político ao mesmo tempo, o que confirma a insuficiência analítica da dicotomia “técnico” ou “político” como critérios de escolha exclusivos pelos chefes dos Executivos. Discussão: O estudo, a partir dessa análise exploratória de dados de um caso específico, abre avenidas para futuras investigações, entre elas a ideia da existência de uma espécie de presidencialismo de coalizão atenuado em alguns estados a ser entendido a partir de dinâmicas especificamente regionais.

ABSTRACT Introduction: Recent studies on the profile of ministers’ appointments at the federal level have shown greater complexity on the logic underlying such decisions and, consequently, the explanatory insufficiency of a dichotomous distinction between “technical” versus “political” appointments. On the other hand, little is known about the types of appointments in state executives. Based on a case study, We compare whether the naming logics are similar or different from those found at the federal level. Materials and Methods: By adopting a qualitative investigation on the biography of all secretaries appointed between 1995 and 2015 in Rio Grande do Norte, Brazil (RN), it was possible to go beyond basic information (such as educational background, professional occupation or party affiliation) of secretaries, identifying the trajectories of individuals in the political and electoral contexts of the state. From there, we propose a typology to measure technical and political competences. Results: The analysis of appointments for the case of RN based on this typology reveals that there are local specificities that explain a significant part of the choices made by governors in setting up their office. The most frequent type of appointment is that of a secretary with a mixed, technical and political profile at the same time, which confirms the analytical insufficiency of the “technical” or “political” dichotomy as a exclusive selection criteria by the heads of Executives. Discussion: Based on this explanatory data analysis of a specific case, the study opens avenues for future investigations, among them the idea of the existence of a kind of attenuated coalition presidentialism in some states to be understood from specifically regional dynamics.

Abstract We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically.

RESUMO Objetivo: conhecer e refletir sobre as melhores práticas em enfermagem e sua interface com o Núcleo Ampliado de Saúde da Família e Atenção Básica. Método: pesquisa participante pautada no referencial metodológico de Paulo Freire e desenvolvida a partir das etapas de investigação temática, codificação, decodificação e desvelamento crítico. As informações foram produzidas e analisadas em quatro Círculos de Cultura, com média de cinco enfermeiras e duração de duas horas cada, entre abril e junho de 2018. A investigação revelou quatro temas geradores, desvelados durante os encontros. Neste estudo será discutido o tema: melhores práticas de enfermagem que favorecem as relações com o Núcleo Ampliado. Resultados: as enfermeiras reconhecem a comunicação como ferramenta que promove as melhores práticas nessa interface. Foi possível aprofundar o diálogo e o conhecimento sobre o tema, sobre o processo de trabalho do Núcleo e o papel da enfermagem nesse contexto. Elas se percebem como elo entre a equipe apoiadora a equipe de Saúde da Família, habilidade decorrente da sua formação voltada para o exercício da gestão e tendo a liderança e o diálogo como recursos para a resolução de conflitos. Conclusão: o estudo contribuiu para o aprimoramento do pensar e do agir das enfermeiras em relação ao tema proposto, pois as reflexões tecidas durante os Círculos impulsionaram atitudes transformadoras nos cenários de prática. Nota-se que a aproximação das enfermeiras com os Núcleos favorece a autonomia e as práticas colaborativas (compreendidas como melhores práticas), estimulando movimentos interprofissionais e resolutivos no âmbito da Atenção Primária.

ABSTRACT Objective: to know and reflect on the best practices in nursing and their interface with the Expanded Family Health and Basic Healthcare Centers (NASF-AB). Method: this is a participatory research based on Paulo Freire’s methodological framework and developed from thematic investigation, coding, decoding, and critical unveiling. The information was produced and analyzed in four Culture Circles, with an average of five nurses and duration of two hours each, between April and June 2018. The investigation revealed four generating themes, unveiled during the meetings. In this study, the theme “best nursing practices that favor relations with NASF-AB” will be discussed. Results: nurses acknowledge communication as a tool that promotes best practices in nursing. It was possible to deepen the dialogue and knowledge about NASF-AB’s work process and the role of nursing. Nurses act as a link between the support team and the Family Health team, a skill resulting from their training focused on management, having leadership and dialogue as resources for conflict resolution. Conclusion: the present study contributed to improve nurses’ thinking and acting in relation to the proposed theme. The reflections made during Culture Circles boosted transformative attitudes in the practice settings. Nurse approximation with NASF-AB favors autonomy and collaborative practices (understood as best practices), encouraging interprofessional and solve-problem actions within Basic Care.

RESUMEN Objetivo: conocer y reflexionar sobre las mejores prácticas en enfermería y su interfaz con el Núcleo Extendido de Salud de la Familia y Atención Primaria (NASF-AB). Método: investigación participativa basada en el marco metodológico de Paulo Freire y desarrollada a partir de las etapas de investigación temática, codificación, decodificación y develación crítica. La información fue producida y analizada en cuatro Círculos de Cultura, con un promedio de cinco enfermeros y una duración de dos horas cada uno, entre abril y junio de 2018. La investigación reveló cuatro temas generadores, develados durante los encuentros. En este estudio se discutirá el tema: mejores prácticas de enfermería que favorecen las relaciones con la NASF-AB. Resultados: las enfermeras reconocen la comunicación como una herramienta que promueve las mejores prácticas en esta interfaz. Se logró profundizar el diálogo y el conocimiento sobre el tema, sobre el proceso de trabajo NASF-AB y el papel de la enfermería en este contexto. Se perciben a sí mismos como un vínculo entre el equipo de apoyo y el equipo de Salud de la Familia, habilidad resultante de su formación enfocada al ejercicio de la gestión y al liderazgo y al diálogo como recursos para la resolución de conflictos. Conclusión: el estudio contribuyó a la mejora del pensamiento y la actuación de los enfermeros en relación con el tema propuesto, ya que las reflexiones realizadas durante los Círculos Culturales estimularon actitudes transformadoras en los escenarios de práctica. Se observa que la aproximación de enfermeras con la NASF-AB favorece la autonomía y las prácticas colaborativas (entendidas como mejores prácticas), estimulando movimientos interprofesionales y resolutivos en el ámbito de la Atención Primaria.