Resumo Nos estudos do cinema de horror mais recentes, evidencia-se a presença do subgênero slasher, conhecido pela presença de assassinatos em série e violência explícita em sua narrativa. Diante desse contexto, questiona-se: como as mulheres — e seus corpos — são representados em uma produção desse gênero? Para responder esse questionamento, utiliza-se como objeto deste estudo o filme X (2022), dirigido por Ti West. Este artigo objetiva compreender a representação da mulher no cinema de horror slasher, utilizando em seu corpo teórico os estudos relacionados ao horror e feminino. Espera-se, com este trabalho, colaborar com as discussões acadêmicas acerca dos estudos de gênero e sexualidade, feminismo e cinema de horror. recentes evidenciase evidencia se slasher narrativa contexto questionase questiona questiona-se questionamento utilizase utiliza 2022, 2022 , (2022) West feminino Esperase, Esperase Espera se, Espera-se trabalho sexualidade 202 (2022 20 (202 2 (20 (2 (

Abstract Recent studies of horror cinema have highlighted the presence of the slasher subgenre, known for the presence of serial murders and explicit violence in its narratives. Given this context, the question arises: how are women — and their bodies — represented in a production of this genre? To answer this question, the film X, directed by Ti West, is used as the object of this study. This article aims to understand the representation of women in slasher horror cinema, using studies related to horror and women in its theoretical framework. It is hoped that this work will contribute to academic discussions on gender and sexuality studies, feminism and horror cinema. subgenre narratives context arises genre X West study framework

Abstract. Introduction : graduation in the health area should equally contemplate the psychomotor, cognitive and affective domains from the problematization of everyday situations of the Unified Health System (SUS). Objective : to evaluate the training of nutritionists based on the integration of knowledge from the teaching-service-community triad, based on Project-Based Learning (PBL) and Collective Portfolio (PC) in the micropolitics of the SUS. Method : a “baby shower” planned and executed by students, guided by a group of teachers, aimed at pregnant women in the SUS network, providing the live work of the concept-tools “alterity”, “bond”, “welcoming”, and “participatory management” was undertaken. Results : records in the CP showed articulation between different knowledge and learning domains in the training of nutritionists by skills. Conclusion: PBL+CP is a powerful and viable teaching-learning tool for the training of professionals capable of working in SUS integrating teachingservice-community.

Resumo Introdução : a formação na área de saúde deve contemplar equanimemente os domínios psicomotor, cognitivo e afetivo a partir da problematização de situações cotidianas do Sistema Único de Saúde (SUS). Objetivo : avaliar a formação do nutricionista a partir da integração de saberes da tríade ensino-serviço-comunidade, a partir da Aprendizagem Baseada em Projetos (ABP) e Portfólio Coletivo (PC) na micropolítica do SUS. Método : Um “chá de bebê” planejado e executado por estudantes, orientado por um grupo de docentes, destinado a gestantes da rede SUS, oportunizando o trabalho vivo dos conceitos-ferramentas ‘alteridade’, ‘vínculo’, ‘acolhimento’, e ‘gestão participativa’ foi empreendido. Resultados : Registros no PC evidenciaram articulação entre diferentes saberes e domínios de aprendizagem na formação do nutricionista por competências. Conclusão : ABP+PC é uma ferramenta de ensino-aprendizagem, potente e viável para a formação do profissional capaz de atuar no SUS integrando ensino-serviço-comunidade.

ABSTRACT Background: Women living with human immunodeficiency virus (HIV) (WLWH) are more likely to be infected with the oncogenic human papillomavirus (HPV). We assessed the prevalence of high-risk (HR) (16/18/31/33/35/39/45/51/52/56/58/59/68/73/82), probable high-risk (pHR) (26/53/66), and low-risk (LR) (6/11/40/42/43/44/54/61/70) HPV types and their associated risk factors. Methods: This cross-sectional study of WLWH aged 18-64 years included one laboratory and eight HIV-specialty healthcare facilities in the pilot network. Descriptive statistics were used to assess sociodemographic and behavioral characteristics. Adjusted analyses were conducted to evaluate risk factors associated with HR and/or pHR HPV infection in WLWH. Results: From May/2021 to May/2022, 1,914 (92.5%) WLWH participated in the pilot study and had valid HPV-DNA results of self-collected vaginal samples. The median age of the participants was 45 years, 60.1% had ≥ 9 years of schooling, 80.5% were ≤ 18 years at first sexual intercourse, and 51.7% had > 4 sexual partners throughout life. The prevalence of any HPV type, HR HPV, pHR HPV, and LR HPV was 65.8%, 49.6%, 16.7%, and 40.0%, respectively. Age was inversely associated with pHR and/or HR-HPV (p < 0.001), and education level was inversely associated with HR-HPV (p = 0.003) types. Any HR or pHR was associated with being single (p = 0.029) and exchanging sex for drugs (p = 0.037). Conclusions: The prevalence of HPV, especially HR HPV, among WLWH is high in Brazil, highlighting the need for HPV screening in this population. Self-collection of vaginal samples is an important strategy for increasing testing access. Background HIV (HIV (WLWH HPV. . (HPV) highrisk (HR 16/18/31/33/35/39/45/51/52/56/58/59/68/73/82, 161831333539455152565859687382 16/18/31/33/35/39/45/51/52/56/58/59/68/73/82 , 16 31 33 35 39 51 52 56 58 59 68 73 82 (16/18/31/33/35/39/45/51/52/56/58/59/68/73/82) (pHR 26/53/66, 265366 26/53/66 26 53 66 (26/53/66) lowrisk low (LR 6/11/40/42/43/44/54/61/70 61140424344546170 6 11 40 42 43 44 54 61 70 (6/11/40/42/43/44/54/61/70 Methods crosssectional cross sectional 1864 64 18-6 HIVspecialty specialty network characteristics andor Results May2021 May 2021 May/202 May2022 2022 May/2022 1914 1 914 1,91 92.5% 925 92 5 (92.5% HPVDNA DNA selfcollected self collected 601 60 60.1 schooling 805 80 80.5 intercourse 517 7 51.7 life type 658 65 8 65.8% 496 49 49.6% 167 16.7% 400 0 40.0% respectively HRHPV p 0.001, 0001 0.001 001 0.001) 0.003 0003 003 0.029 0029 029 0.037. 0037 0.037 037 0.037) Conclusions Brazil population Selfcollection Self collection access (HPV 16183133353945515256585968738 16/18/31/33/35/39/45/51/52/56/58/59/68/73/8 3 (16/18/31/33/35/39/45/51/52/56/58/59/68/73/82 26536 26/53/6 2 (26/53/66 6/11/40/42/43/44/54/61/7 6114042434454617 (6/11/40/42/43/44/54/61/7 186 18- May202 202 May/20 191 91 1,9 92.5 (92.5 60. 80. 51. 65.8 49.6 16.7 40.0 000 0.00 00 0.02 002 02 0.03 03 1618313335394551525658596873 16/18/31/33/35/39/45/51/52/56/58/59/68/73/ (16/18/31/33/35/39/45/51/52/56/58/59/68/73/8 2653 26/53/ (26/53/6 6/11/40/42/43/44/54/61/ 611404243445461 (6/11/40/42/43/44/54/61/ May20 20 May/2 19 1, 92. 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Abstract The objective of this study was to compare the protein profile of the acquired enamel pellicle (AEP) formed in vivo in patients with or without gastroesophageal reflux disease (GERD), and with or without erosive tooth wear (ETW). Twenty-four volunteers were divided into 3 groups: 1) GERD and ETW; 2) GERD without ETW; and 3) control (without GERD). The AEP formed 120 min after prophylaxis was collected from the lingual/palatal surfaces. The samples were subjected to mass spectrometry (nLC-ESI-MS/MS) and label-free quantification by Protein Lynx Global Service software. A total of 213 proteins were identified, or 119, 92 and 106 from each group, respectively. Group 2 showed a high number of phosphorylated and calcium-binding proteins. Twenty-three proteins were found in all the groups, including 14-3-3 protein zeta/delta and 1-phosphatidylinositol. Several intracellular proteins that join saliva after the exfoliation of oral mucosa cells might have the potential to bind hydroxyapatite, or participate in forming supramolecular aggregates that bind to precursor proteins in the AEP. Proteins might play a central role in protecting the dental surface against acid dissolution. (AEP GERD, , (GERD) ETW. ETW . (ETW) Twentyfour Twenty four groups 1 GERD. GERD) 12 lingualpalatal lingual palatal surfaces nLCESIMS/MS nLCESIMSMS nLC ESI MS/MS MS (nLC-ESI-MS/MS labelfree label free software 21 identified 119 9 10 group respectively calciumbinding calcium binding Twentythree three 1433 14 14-3- zetadelta zeta delta 1phosphatidylinositol. 1phosphatidylinositol phosphatidylinositol phosphatidylinositol. 1-phosphatidylinositol hydroxyapatite dissolution (GERD (ETW nLCESIMS MSMS 11 143 14-3 14-

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System. (OMPLs SCC. . (SCC) crosssectional cross sectional North, North (North Northeast CentralWest, CentralWest Central West, West Central-West South. South South) 201 120010 120 010 120,01 20102019, 20102019 , (2010-2019) 69 6 9 6.9 8,321 8321 8 321 (8,32 0.8%, 08 0 (0.8% 95 cases, 4.9%, 49 4 (4.9% 5971 5 971 5,97 1.2%, 12 1 2 (1.2% 1399 399 1,39 Brazils s 64.5%, 645 64.5% 64 (64.5%) located men years level consumption group nonCaucasian non formercurrent former users Institute 99 9.9 Therefore System (SCC 20 12001 01 120,0 2010201 (2010-2019 6. 8,32 832 32 (8,3 0.8% (0.8 4.9% (4.9 597 97 5,9 1.2% (1.2 139 39 1,3 64.5 (64.5% 9. 1200 120, 201020 (2010-201 8,3 83 3 (8, 0.8 (0. 4.9 (4. 59 5, 1.2 (1. 13 1, 64. (64.5 20102 (2010-20 8, (8 0. (0 4. (4 1. (1 (64. (2010-2 ( (64 (2010- (6 (2010 (201 (20 (2

Resumo O objetivo deste trabalho foi avaliar a dinâmica populacional do percevejo-castanho (Scaptocoris castanea) em área com algodão (Gossypium hirsutum) cultivado após plantas de cobertura. Os insetos foram contados em amostras de solo coletadas a 0-40 cm de profundidade. A incidência de insetos foi documentada em 18 espécies de cobertura, isoladas ou consorciadas, em cada estágio da planta. A distribuição das chuvas foi comparada com a flutuação populacional do inseto. Espécies de crotalária apresentam efeito supressivo sobre a população do percevejo-castanho, enquanto algumas espécies de gramíneas favorecem o seu aumento. A distribuição das chuvas influencia diretamente a população de insetos.

Abstract The objective of this work was to evaluate the population dynamics of the burrower bug (Scaptocoris castanea) in an area with cotton (Gossypium hirsutum) cultivated after cover crops. The insects were counted in soil samples collected at 0-40 cm depth. Insect incidence was documented in 18 cover crops, alone or intercropped, in each plant stage. Rainfall distribution was compared with fluctuations in the burrower bug population. Crotalaria species have a suppressive effect on the insect population, whereas some grass species favor its increase. Rainfall distribution directly influences the insect population.

RESUMO A retinopatia lúpica é uma manifestação clínica do lúpus eritematoso sistêmico no sistema visual. Geralmente assintomática, porém pode ser uma condição ameaçadora à visão. Está intimamente associada à atividade inflamatória do lúpus eritematoso sistêmico e ao aumento da mortalidade. A retinopatia lúpica tem diversas apresentações clínicas, como a microangiopatia lúpica, oclusão vascular, vasculite, retinopatia hipertensiva associada à nefrite lúpica e retinopatia autoimune. A prevalência e os fatores associados à retinopatia lúpica estão bem definidos em algumas partes do mundo. No entanto, esses dados são pouco conhecidos na América Latina, incluindo o Brasil. Como a retinopatia lúpica é geralmente assintomática, sem a fundoscopia de rotina, provavelmente esta é subestimada. O objetivo desta revisão é discutir a epidemiologia e fatores de risco para retinopatia lúpica.

ABSTRACT Lupus retinopathy is a clinical manifestation of systemic lupus erythematosus in the visual system. It is generally asymptomatic; however, it can become a threatening condition. It is closely associated with the inflammatory activity and higher mortality of systemic lupus erythematosus. Lupus retinopathy has several different clinical presentations, such as lupus microangiopathy, vascular occlusion, vasculitis, hypertensive retinopathy associated with lupus nephritis, and autoimmune retinopathy. Although the prevalence and associated factors of lupus retinopathy have been well defined in some parts of the world, there are no data from Latin America, including Brazil. As lupus retinopathy is generally asymptomatic, without a routine fundoscopy, it has been probably underestimated. This review is intended to discuss the epidemiology and risk factors of lupus retinopathy.

Abstract Paper aims This paper presents the methodological development of a sustainability indicator focused on the local level, based on the Municipal Human Development Index (MHDI). Originality The proposed indicator (MHDI+S) was built on the use of an indicator with simple methodology based on information provided by reliable Brazilian research institutes, making it easier to be updated and reproduced in other regions and states. Research method By adding the environmental factor to this well-known index, the proposed indicator (MHDI+S) is then applied to the state of Rio de Janeiro, Brazil, so that the municipalities have been categorized into different clusters. Main findings The results of this categorization were validated by statistical assessment (cluster analysis) showing that the groups have internal homogeneity and external heterogeneity. Implications for theory and practice The proposed indicator (MHDI+S) can assist public management at the local level, decentralizing the well-established federal perspective,

Abstract Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2), is the largest pandemic in modern history with very high infection rates and considerable mortality. The disease, which emerged in China’s Wuhan province, had its first reported case on December 29, 2019, and spread rapidly worldwide. On March 11, 2020, the World Health Organization (WHO) declared the COVID-19 outbreak a pandemic and global health emergency. Since the outbreak, efforts to develop COVID-19 vaccines, engineer new drugs, and evaluate existing ones for drug repurposing have been intensively undertaken to find ways to control this pandemic. COVID-19 therapeutic strategies aim to impair molecular pathways involved in the virus entrance and replication or interfere in the patients’ overreaction and immunopathology. Moreover, nanotechnology could be an approach to boost the activity of new drugs. Several COVID-19 vaccine candidates have received emergency-use or full authorization in one or more countries, and others are being developed and tested. This review assesses the different strategies currently proposed to control COVID-19 and the issues or limitations imposed on some approaches by the human and viral genetic variability.

ABSTRACT. Sustainable production systems, such as the no-tillage system (NTS), have a tendency to increase organic carbon in the soil. However, in Brazilian cotton production, the conventional tillage system (CTS) is predominant, and long-term studies on cotton crop under the NTS are scarce. The present study aimed to evaluate the effect of soil management and crop rotation systems on the cotton fiber yield as well as on the carbon and nitrogen accumulation in the soil. This study was conducted in the Brazilian savanna over 9 years and consisted of the following four treatments with different soil management systems: the NTS and CTS with the succession or rotation of crops (cotton, soybean, maize, and Urochloa ruziziensis). The NTS increased the carbon content by 55% in the top 5 cm after 9 years and increased the carbon stock by approximately 20% at a depth of up to 40 cm. Crop rotation with soybean, maize, and cotton was insufficient to increase the carbon stock in the soil under the CTS. In addition to increasing the fiber yield, the cotton crop in a NTS rotated with soybean + U. ruziziensis and with maize + U. ruziziensis increases the carbon stock and nitrogen content in soil.

A síndrome da imunodeficiência adquirida é identificada pela intensa imunodepressão do hospedeiro, causada pelo vírus da imunodeficiência humana. Assim, objetivou-se analisar o resultado da avaliação subjetiva global com o índice de massa corporal para obtenção do diagnóstico nutricional. Os dados da Avaliacão subjetiva global foram coletados pelos prontuários e logo em seguida foi aferida a avaliação antropométrica, sendo composta por massa corporal e altura. A classificação do índice de massa corporal foi 26,6% baixo peso, 53,4% normal e 20% excesso de peso. Ao correlacionar os resultados da ASG com o IMC, foi possível observar que dos 70% dos pacientes bem nutridos pela ASG, 14% baixo peso, 57% normal, 28% excesso de peso. A população que corresponde a 30% da amostra relativo aos pacientes desnutridos possui uma classificação de índice de massa corporal dividida em: baixo peso e normal. Analisando essa amostra, observou-se que 55% baixo peso e os demais 45% normal. Apesar da maioria dos pacientes estarem eutróficos de acordo com o IMC, a desnutrição esteve presente em um número considerável de indivíduos, superando os casos de excesso de massa corporal.

Acquired immunodeficiency syndrome is identified by the intense immunodepression of the host, caused by the human immunodeficiency virus. The objective was to analyze the result of the global subjective evaluation with the body mass index to obtain the nutritional diagnosis. The data of the global subjective evaluation were collected by the charts and immediately afterwards the anthropometric evaluation was evaluated, being composed by weight and height. The classification of the body mass index was 26.6% underweight, 53.4% normal and 20% overweight. When correlating ASG results with BMI, it is possible to observe that of the 70% of patients well nourished by ASG, 14% underweight, 57% normal, 28% overweight. The population corresponding to 30% of the sample for malnourished patients has a BMI classification divided into: low and normal. Analyzing this sample, we have 55% underweight and the other 45% normal. Although most of the patients were eutrophic according to the BMI, malnutrition was present in a considerable number of individuals, overcoming cases of overweight.

Objetivou-se verificar o estado nutricional de crianças que frequentavam instituições públicas e privadas com base em medidas antropométricas. Foi realizada uma avaliação do Estado Nutricional das crianças de 02 a 04 anos de idade, da rede pública e outra privada. O estado antropométrico foi avaliado a partir do IMC (IMC/Idade), P/I (peso para idade), E/I (estatura para idade), e P/E (peso para estatura). Os dados foram coletados de acordo com as medidas antropométricas e posteriormente processados nas tabelas da WHO 2006. De acordo com o parâmetro P/I 11,11% (n=3) das crianças da creche pública estavam com peso elevado para idade. Analisando o mesmo parâmetro, foi possível observar que 6,5% (n=2) das crianças da creche particular apresentaram peso elevado para idade. Em relação ao índice E/I, 11,11% (n=3) das crianças da rede pública foi diagnosticada com baixa estatura, enquanto que as da rede particular mostrou 100% de adequação nesse para parâmetro. O indicador IMC/I apresentou uma prevalência de 44,44% (n=12) e 16,1 (n=5) de obesidade nas crianças da creche pública e particular, respectivamente. De acordo com o P/E 55,6% (n=15) das crianças da rede pública apresentou obesidade, e 16,1% (n=5) da creche particular apresentaram o mesmo diagnostico. De acordo com os resultados obtidos, concluiu-se que existe um aumento do excesso de peso nas crianças da rede pública quando comparado com as da rede privada.

The objective was to verify the nutritional status of children attending public and private institutions based on anthropometric measures. An evaluation of the Nutritional Status of children from 02 to 04 years old, from the public and private schools was carried out. The anthropometric status was evaluated from BMI (BMI / Age), P / I (weight for age), E / I (height for age), and P / E (weight for height). Data were collected according to the anthropometric measures and later processed in WHO tables. According to the P / I parameter, 11.11% (n = 3) of the day care center children were weight-for-age. Analyzing the same parameter, it was possible to observe that 6.5% (n = 2) of the children in the private day care center presented weight for age. Regarding the E / I index, 11.11% (n = 3) of the children in the public network was diagnosed with short stature, while those in the private network showed 100% adequacy in this parameter. The IMC / I indicator presented a prevalence of 44.44% (n = 12) and 16.1 (n = 5) of obesity in children in the public and private day care centers, respectively. According to the P / E, 55.6% (n = 15) of the children in the public network presented obesity, and 16.1% (n = 5) of the private day care center presented the same diagnosis. According to the results, it was concluded that there is an increase in overweight in the children of the public network when compared to those of the private network.