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RESUMO Introdução: Doenças pulmonares são comuns em pacientes com doença renal em estágio terminal (DRET), dificultando o diagnóstico diferencial com COVID-19. Este estudo descreve achados de tomografia computadorizada de tórax (TC) em pacientes com DRET em terapia renal substitutiva (TRS) hospitalizados com suspeita de COVID-19. Métodos: Indivíduos maiores de 18 anos com DRET, encaminhados ao pronto-socorro com suspeita de COVID-19 foram incluídos. Dados clínicos e epidemiológicos foram extraídos de registros eletrônicos de saúde. A TC foi classificada como típica, indeterminada, atípica, negativa. Comparamos achados tomográficos de pacientes com COVID-19 positivos e negativos. Resultados: Recrutamos 109 pacientes (62,3% COVID-19-positivos) entre março e dezembro de 2020, idade média de 60 ± 12,5 anos, 43% mulheres. A etiologia mais comum da DRET foi diabetes. Tempo médio em diálise foi 36 meses, intervalo interquartil = 12–84. A lesão pulmonar mais comum foi opacidades em vidro fosco. O padrão típico de TC foi mais comum em pacientes com COVID-19 (40 (61%) vs. 0 (0%) em pacientes sem COVID-19, p < 0,001). Sensibilidade 60,61% (40/66), especificidade 100% (40/40). Valores preditivos positivos e negativos foram 100% e 62,3%, respectivamente. Padrão atípico de TC foi mais frequente em pacientes COVID-19-negativos (9 (14%) vs. 24 (56%) em COVID-19-positivos, p < 0,001), enquanto padrão indeterminado foi semelhante em ambos os grupos (13 (20%) vs. 6 (14%), p = 0,606), e padrão negativo foi mais comum em pacientes COVID-19-negativos (4 (6%) vs. 12 (28%), p = 0,002). Conclusões: Em pacientes com DRET em TRS hospitalizados, um padrão atípico de TC de tórax não pode excluir adequadamente o diagnóstico de COVID-19. Introdução , (DRET) COVID19. COVID19 COVID 19. 19 (TC (TRS Métodos 1 prontosocorro pronto socorro COVID-1 incluídos saúde típica indeterminada atípica negativa Resultados 10 62,3% 623 62 3 (62,3 COVID19positivos COVIDpositivos COVID-19-positivos 2020 125 5 12, 43 mulheres diabetes meses 1284 84 12–84 fosco 40 61% 61 (61% vs 0% (0% COVID19, 19, 0,001. 0001 0,001 . 001 0,001) 6061 60,61 40/66, 4066 40/66 66 (40/66) 100 40/40. 4040 40/40 (40/40) respectivamente COVID19negativos COVIDnegativos 9 ( 14% 14 (14% 2 56% 56 (56% COVID19positivos, positivos, 0,001, 13 (1 20% 20 (20% 14%, 0,606, 0606 0,606 606 0,606) 4 6% (6% 28%, 28 28% (28%) 0,002. 0002 0,002 002 0,002) Conclusões (DRET COVID1 COVID- 62,3 (62, 202 128 8 12–8 (61 (0 000 0,00 00 60,6 406 40/6 (40/66 404 40/4 (40/40 (14 (56 (20 060 0,60 (6 (28% 62, (62 12– 0,0 60, 40/ (40/6 (40/4 (5 (2 06 0,6 (28 0, (40/

ABSTRACT Introduction: Lung diseases are common in patients with end stage kidney disease (ESKD), making differential diagnosis with COVID-19 a challenge. This study describes pulmonary chest tomography (CT) findings in hospitalized ESKD patients on renal replacement therapy (RRT) with clinical suspicion of COVID-19. Methods: ESKD individuals referred to emergency department older than 18 years with clinical suspicion of COVID-19 were recruited. Epidemiological baseline clinical information was extracted from electronic health records. Pulmonary CT was classified as typical, indeterminate, atypical or negative. We then compared the CT findings of positive and negative COVID-19 patients. Results: We recruited 109 patients (62.3% COVID-19-positive) between March and December 2020, mean age 60 ± 12.5 years, 43% female. The most common etiology of ESKD was diabetes. Median time on dialysis was 36 months, interquartile range = 12–84. The most common pulmonary lesion on CT was ground glass opacities. Typical CT pattern was more common in COVID-19 patients (40 (61%) vs 0 (0%) in non-COVID-19 patients, p < 0.001). Sensitivity was 60.61% (40/66) and specificity was 100% (40/40). Positive predictive value and negative predictive value were 100% and 62.3%, respectively. Atypical CT pattern was more frequent in COVID-19-negative patients (9 (14%) vs 24 (56%) in COVID-19-positive, p < 0.001), while the indeterminate pattern was similar in both groups (13 (20%) vs 6 (14%), p = 0.606), and negative pattern was more common in COVID-19-negative patients (4 (6%) vs 12 (28%), p = 0.002). Conclusions: In hospitalized ESKD patients on RRT, atypical chest CT pattern cannot adequately rule out the diagnosis of COVID-19. Introduction ESKD, , (ESKD) COVID19 COVID 19 COVID-1 challenge (CT RRT (RRT COVID19. 19. Methods 1 records typical Results 10 62.3% 623 62 3 (62.3 COVID19positive COVIDpositive COVID-19-positive 2020 125 5 12. 43 female diabetes months 1284 84 12–84 opacities 40 61% 61 (61% 0% (0% nonCOVID19 nonCOVID non non-COVID-1 0.001. 0001 0.001 . 001 0.001) 6061 60.61 40/66 4066 66 (40/66 100 40/40. 4040 40/40 (40/40) respectively COVID19negative COVIDnegative 9 ( 14% 14 (14% 2 56% 56 (56% COVID19positive, positive, 0.001, 13 (1 20% 20 (20% 14%, 0.606, 0606 0.606 606 0.606) 4 6% (6% 28%, 28 28% (28%) 0.002. 0002 0.002 002 0.002) Conclusions (ESKD COVID1 COVID- 62.3 (62. 202 128 8 12–8 (61 (0 nonCOVID1 non-COVID- 000 0.00 00 60.6 40/6 406 (40/6 404 40/4 (40/40 (14 (56 (20 060 0.60 (6 (28% 62. (62 12– non-COVID 0.0 60. 40/ (40/ (40/4 (5 (2 06 0.6 (28 0.

https://doi.org/10.1590/2175-8239-jbn-2023-0029en

Translation, cross-cultural adaptation and validation of the Short Screening Instrument for Psychological Problems in Enuresis for use in Brazil (SSIPPE-Br) Translation crosscultural cross cultural SSIPPEBr SSIPPE Br (SSIPPE-Br
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Dias, Gláucia Cristina Medeiros

; Vasconcelos, Mônica Maria de Almeida

; Bastos Netto, José Murillo

; Miranda, Débora Marques de

; Lima, Eleonora Moreira

; Silva, Ana Cristina Simões e

; Moreira, Janaina Matos

; Mrad, Flávia Cristina de Carvalho

Jornal de Pediatria

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Abr 2024, Volume 100 Nº 2 Páginas 218 - 225

Resumo: En | Texto: En | PDF: En

Abstract Objective: Enuresis is associated with attentional and emotional comorbidities in 20 to 30 % of cases. The Short Screening Instrument for Psychological Problems in Enuresis (SSIPPE) is a questionnaire that allows the initial screening of these comorbidities. This study aimed to translate, culturally adapt, and validate the SSIPPE for Brazilian children and adolescents (SSIPPE-Br). Methods: Six steps were performed for translation and cross-cultural adaptation: translation, synthesis of translations, back-translation, preparation of the pre-final version of the translated instrument, test of comprehensibility of the pre-final version of the tool, and elaboration of the instrument cross-culturally adapted for Brazil, named 13-itens version SSIPPE-Br. To validate the SSIPPE-Br, a cross-sectional study was carried out, in which the validated Brazilian version of the Child and Adolescent Behavior Inventory (CABI) was used. Results: Validation was performed on 127 children and adolescents with a mean age of 9.7 ± 2.8 years, 48 % male. The reliability was estimated using Cronbach’s alpha, ranging from 0.86 to 0.89, indicating good internal consistency. The factorial analysis had a good agreement adjustment (KMO 0.755, Bartlett’s test < 0.001) and explained 70.5 % of the data variability. In the reproducibility analysis, the Kappa coefficient ranged from 0.94 to 1, which can be considered almost perfect. A highly significant (p-value < 0.001) and direct correlation existed between the three SSIPPE-Br domains and all evaluated CABI domains. Conclusion: The SSIPPE-Br is a valid and reliable tool for emotional problems screening and ADHD symptoms in children and adolescents with enuresis whose first language is Brazilian Portuguese. Objective 2 3 cases (SSIPPE translate adapt SSIPPEBr. SSIPPEBr Br . (SSIPPE-Br) Methods crosscultural cross cultural adaptation translations backtranslation, backtranslation back back-translation prefinal pre final crossculturally Brazil 13itens itens 13 Br. SSIPPEBr, Br, crosssectional sectional out (CABI used Results 12 97 9 7 9. 28 8 2. years 4 male Cronbachs Cronbach s alpha 086 0 86 0.8 089 89 0.89 consistency KMO 0755 755 0.755 Bartletts Bartlett 0.001 0001 001 705 70 5 70. variability 094 94 0.9 1 perfect pvalue p value Conclusion Portuguese (SSIPPE-Br 08 0. 075 75 0.75 0.00 000 00 09 07 0.7 0.0

https://doi.org/10.1016/j.jped.2023.11.001

Diretriz Brasileira sobre a Saúde Cardiovascular no Climatério e na Menopausa – 2024 202 20 2
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Oliveira, Gláucia Maria Moraes de

; Almeida, Maria Cristina Costa de

; Arcelus, Carolina María Artucio

; Neto Espíndola, Larissa

; Rivera, Maria Alayde Mendonça

; Silva-Filho, Agnaldo Lopes da

; Marques-Santos, Celi

; Fernandes, César Eduardo

; Albuquerque, Carlos Japhet da Matta

; Freire, Claudia Maria Vilas

; Izar, Maria Cristina de Oliveira

; Costa, Maria Elizabeth Navegantes Caetano

; Castro, Marildes Luiza de

; Lemke, Viviana de Mello Guzzo

; Lucena, Alexandre Jorge Gomes de

; Brandão, Andréa Araujo

; Macedo, Ariane Vieira Scarlatelli

; Polanczyk, Carisi Anne

; Lantieri, Carla Janice Baister

; Nahas, Eliana Petri

; Alexandre, Elizabeth Regina Giunco

; Campana, Erika Maria Gonçalves

; Bragança, Érika Olivier Vilela

; Colombo, Fernanda Marciano Consolim

; Barbosa, Imara Correia de Queiroz

; Rivera, Ivan Romero

; Kulak, Jaime

; Moura, Lidia Ana Zytynski

; Pompei, Luciano de Mello

; Baccaro, Luiz Francisco Cintra

; Barbosa, Marcia Melo

; Rodrigues, Marcio Alexandre Hipólito

; Albernaz, Marco Aurelio

; Decoud, Maria Sotera Paniagua de

; Paiva, Maria Sanali Moura de Oliveira

; Sanchez-Zambrano, Martha Beatriz

; Campos, Milena dos Santos Barros

; Acevedo, Monica

; Ramirez, Monica Susana

; Souza, Olga Ferreira de

; Medeiros, Orlando Otávio de

; Carvalho, Regina Coeli Marques de

; Machado, Rogerio Bonassi

; Silva, Sheyla Cristina Tonheiro Ferro da

; Rodrigues, Thais de Carvalho Vieira

; Avila, Walkiria Samuel

; Costa-Paiva, Lucia Helena Simões da

; Wender, Maria Celeste Osorio

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 Nº 7 elocation e20240478

Resumo: Pt | Texto: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240478

Brazilian Guideline on Menopausal Cardiovascular Health – 2024 202 20 2
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Oliveira, Gláucia Maria Moraes de

; Almeida, Maria Cristina Costa de

; Arcelus, Carolina María Artucio

; Espíndola Neto, Larissa

; Rivera, Maria Alayde Mendonça

; Silva-Filho, Agnaldo Lopes da

; Marques-Santos, Celi

; Fernandes, César Eduardo

; Albuquerque, Carlos Japhet da Matta

; Freire, Claudia Maria Vilas

; Izar, Maria Cristina de Oliveira

; Costa, Maria Elizabeth Navegantes Caetano

; Castro, Marildes Luiza de

; Lemke, Viviana de Mello Guzzo

; Lucena, Alexandre Jorge Gomes de

; Brandão, Andréa Araujo

; Macedo, Ariane Vieira Scarlatelli

; Polanczyk, Carisi Anne

; Lantieri, Carla Janice Baister

; Nahas, Eliana Petri

; Alexandre, Elizabeth Regina Giunco

; Campana, Erika Maria Gonçalves

; Bragança, Érika Olivier Vilela

; Colombo, Fernanda Marciano Consolim

; Barbosa, Imara Correia de Queiroz

; Rivera, Ivan Romero

; Kulak, Jaime

; Moura, Lidia Ana Zytynski

; Pompei, Luciano de Mello

; Baccaro, Luiz Francisco Cintra

; Barbosa, Marcia Melo

; Rodrigues, Marcio Alexandre Hipólito

; Albernaz, Marco Aurelio

; Decoud, Maria Sotera Paniagua de

; Paiva, Maria Sanali Moura de Oliveira

; Sanchez-Zambrano, Martha Beatriz

; Campos, Milena dos Santos Barros

; Acevedo, Monica

; Ramirez, Monica Susana

; Souza, Olga Ferreira de

; Medeiros, Orlando Otávio de

; Carvalho, Regina Coeli Marques de

; Machado, Rogerio Bonassi

; Silva, Sheyla Cristina Tonheiro Ferro da

; Rodrigues, Thais de Carvalho Vieira

; Avila, Walkiria Samuel

; Costa-Paiva, Lucia Helena Simões da

; Wender, Maria Celeste Osorio

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo100

Resumo: En | Texto: En | PDF: En

https://doi.org/10.61622/rbgo/2024rbgo100

Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer ChAdOx SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- arthritis SARS-CoV
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Cruz, Vitor Alves

; Guimarães, Camila

; Rêgo, Jozelia

; Machado, Ketty Lysie Libardi Lira

; Miyamoto, Samira Tatiyama

; Burian, Ana Paula Neves

; Dias, Laiza Hombre

; Pretti, Flavia Zon

; Batista, Danielle Cristina Filgueira Alves

; Mill, José Geraldo

; Oliveira, Yasmin Gurtler Pinheiro de

; Gadelha, Carolina Strauss Estevez

; Gouveia, Maria da Penha Gomes

; Moulin, Anna Carolina Simões

; Souza, Bárbara Oliveira

; Aguiar, Laura Gonçalves Rodrigues

; Vieira, Gabriel Smith Sobral

; Grillo, Luiza Lorenzoni

; Lima, Marina Deorce de

; Pasti, Laís Pizzol

; Surlo, Heitor Filipe

; Faé, Filipe

; Moulaz, Isac Ribeiro

; Macabú, Mariana de Oliveira

; Ribeiro, Priscila Dias Cardoso

; Magalhães, Vanessa de Oliveira

; Aguiar, Mariana Freitas de

; Biegelmeyer, Erika

; Peixoto;, Flávia Maria Matos Melo Campos

; Kayser, Cristiane

; Souza, Alexandre Wagner Silva de

; Castro, Charlles Heldan de Moura

; Ribeiro, Sandra Lúcia Euzébio

; Telles, Camila Maria Paiva França

; Bühring, Juliana

; Lima, Raquel Lima de

; Santos, Sérgio Henrique Oliveira Dos

; Dias, Samuel Elias Basualto

; Melo, Natália Seixas de

; Sanches, Rosely Holanda da Silva

; Boechat, Antonio Luiz

; Sartori, Natália Sarzi

; Hax, Vanessa

; Dória, Lucas Denardi

; Rezende, Rodrigo Poubel Vieira de

; Baptista, Katia Lino

; Fortes, Natália Rodrigues Querido

; Melo, Ana Karla Guedes de

; Melo, Tâmara Santos

; Vieira, Rejane Maria Rodrigues de Abreu

; Vieira, Adah Sophia Rodrigues

; Kakehasi, Adriana Maria

; Tavares, Anna Carolina Faria Moreira Gomes

; Landa, Aline Teixeira de

; Costa, Pollyana Vitoria Thomaz da

; Azevedo, Valderilio Feijó

; Martins-Filho, Olindo Assis

; Peruhype-Magalhães, Vanessa

; Pinheiro, Marcelo de Medeiros

; Monticielo, Odirlei André

; Reis-neto, Edgard Torres Dos

; Ferreira, Gilda Aparecida

; Souza, Viviane Angelina de

; Teixeira-Carvalho, Andréa

; Xavier, Ricardo Machado

; Sato, Emilia Inoue

; Valim, Valeria

; Pileggi, Gecilmara Salviato

; Silva, Nilzio Antonio da

Advances in Rheumatology

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2024, Volume 64 elocation 58

Resumo: En | Texto: En | PDF: En

Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26

https://doi.org/10.1186/s42358-024-00397-5

Pediatric chronic kidney disease: blood cell count indexes as inflammation markers disease
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Silva, Aislander Junio da

; Santos Lopes, Ana Cristina dos

; Mota, Ana Paula Lucas

; Silva, Ana Cristina Simões e

; Dusse, Luci Maria Sant’Ana

; Alpoim, Patrícia Nessralla

Brazilian Journal of Nephrology

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Dez 2023, Volume 45 Nº 4 Páginas 458 - 469

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Introdução: Doença renal crônica (DRC) é definida como um declínio progressivo das funções renais. Na infância, os principais fatores desencadeantes são anomalias congênitas dos rins e trato urinário (CAKUT) e glomerulopatias. Respostas inflamatórias apresentam desafios para diagnóstico e estadiamento, o que justifica estudos sobre biomarcadores/índices. Objetivo: Definir índices de contagem de células sanguíneas e verificar sua associação com etiologia e estadiamento da DRC pediátrica. Os índices incluídos foram: Razão Neutrófilo-Linfócito (NLR), Razão Neutrófilo-Linfócito Derivada (dNLR), Razão Linfócito-Monócito (LMR), Índice de Resposta à Inflamação Sistêmica (SIRI), Índice Agregado de Inflamação Sistêmica (AISI) e Índice de Inflamação Imune Sistêmica (SII). Métodos: Determinamos índices em 52 pacientes pediátricos com DRC e 33 controles saudáveis por cálculo matemático. Pacientes com DRC foram separados em cinco grupos conforme etiologia e estadiamento: Grupo IA: glomerulopatias em estágio 1 ou 2; IB: glomerulopatias em estágio 3 ou 4; IIA: CAKUT em estágio 1 ou 2; IIB: CAKUT em estágio 3 ou 4; e III: estágios 3 ou 4 de outras etiologias. Além disso, combinamos todos os pacientes com DRC em um grupo (IV). Grupo V foi um grupo controle saudável. Resultados: Observamos valores menores de LMR nos grupos IB e IIB comparados ao grupo V (p=0,047; p=0,031, respectivamente). Encontramos valores maiores de SIRI para o grupo III versus grupo V (p=0,030). Não houve diferença para outros índices quando os grupos foram comparados dois a dois. Conclusão: Os índices LMR e SIRI apresentaram resultados promissores na avaliação da inflamação, pois correlacionaram-se com as etiologias da DRC e, principalmente, com o estadiamento desses pacientes. Introdução (DRC renais infância (CAKUT biomarcadoresíndices biomarcadores biomarcadores/índices Objetivo pediátrica NeutrófiloLinfócito Neutrófilo Linfócito NLR, NLR , (NLR) dNLR, dNLR (dNLR) LinfócitoMonócito Monócito LMR, (LMR) SIRI, (SIRI) AISI (AISI SII. SII . (SII) Métodos 5 matemático IA 2 IIA disso IV. IV (IV) saudável Resultados p=0,047 p0047 p 0 047 (p=0,047 p0031 031 p=0,031 respectivamente. respectivamente respectivamente) p=0,030. p0030 p=0,030 030 (p=0,030) Conclusão inflamação correlacionaramse correlacionaram se principalmente (NLR (dNLR (LMR (SIRI (SII (IV p=0,04 p004 04 (p=0,04 p003 03 p=0,03 (p=0,030 p=0,0 p00 (p=0,0 (p=0,03 p=0, p0 (p=0, p=0 (p=0 p= (p= (p

Abstract Introduction: Chronic kidney disease (CKD) is defined as a progressive decline of kidney functions. In childhood, the main triggering factors are congenital anomalies of the kidneys and urinary tract (CAKUT) and glomerulopathies. Inflammatory responses present challenges for diagnosis and staging, which justifies studies on biomarkers/indexes. Aim: To define blood cell count indexes and verify their association with pediatric CKD etiology and staging. The included indexes were: Neutrophil-Lymphocyte Ratio (NLR), Derived Neutrophil-Lymphocyte Ratio (dNLR), Lymphocyte-Monocyte Ratio (LMR), Systemic Inflammation Response Index (SIRI), Aggregate Index of Systemic Inflammation (AISI), and Systemic Immune-Inflammation Index (SII). Methods: We determined the indexes in 52 pediatric CKD patients and 33 healthy controls by mathematical calculation. CKD patients were separated in five groups based on the etiology and staging: Group IA: glomerulopathies at stage 1 or 2; IB: glomerulopathies at stage 3 or 4; IIA: CAKUT at stage 1 or 2; IIB: CAKUT at stage 3 or 4; and III: stages 3 or 4 of other etiologies. In addition, we combined all patients with CKD in one group (IV). Group V was a healthy control group. Results: Lower values of LMR were observed for groups IB and IIB compared to group V (p = 0.047, p = 0.031, respectively). Increased values of SIRI were found for group III versus group V (p = 0.030). There was no difference for other indexes when the groups were compared two by two. Conclusion: The LMR and SIRI indexes showed promising results in the evaluation of inflammation, as they correlated with CKD etiologies and specially staging in these patients. Introduction (CKD functions childhood (CAKUT biomarkersindexes biomarkers biomarkers/indexes Aim NeutrophilLymphocyte Neutrophil Lymphocyte NLR, NLR , (NLR) dNLR, dNLR (dNLR) LymphocyteMonocyte Monocyte LMR, (LMR) SIRI, (SIRI) AISI, AISI (AISI) ImmuneInflammation Immune SII. SII . (SII) Methods 5 calculation IA 2 IIA addition IV. IV (IV) Results 0047 0 047 0.047 0031 031 0.031 respectively. respectively respectively) 0.030. 0030 0.030 030 0.030) Conclusion inflammation (NLR (dNLR (LMR (SIRI (AISI (SII (IV 004 04 0.04 003 03 0.03 00 0.0 0.

https://doi.org/10.1590/2175-8239-jbn-2022-0190en

Validation of the Vancouver Symptom Score Questionnaire for bladder and bowel dysfunction for Brazilian children and adolescents
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Pinto, Fernanda Nunes Coelho Siqueira

; de Bessa Junior, José

; Bastos Netto, José Murillo

; Dias, Gláucia Cristina Medeiros

; Vasconcelos, Mônica Maria de Almeida

; Lima, Eleonora Moreira

; Almeida, Tailly de Souza

; Silva, Ana Cristina Simões e

; Mrad, Flávia Cristina de Carvalho

International braz j urol

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Fev 2023, Volume 49 Nº 1 Páginas 110 - 122

Resumo: En | Texto: En | PDF: En

ABSTRACT Objective: This study aimed to translate, and perform a cross-cultural adaptation, and validation of the Vancouver Symptom Score (VSS) for bladder and bowel dysfunction (BBD) for Brazilian children and adolescents Materials and Methods: Six steps were performed for the translation and cross-cultural adaptation: (1) translation, (2) synthesis of translations, (3) back-translation, (4) pre-final version of the translated instrument, (5) pilot test and degree of comprehensibility and (6) elaboration of the Brazilian version of the VSS. For validation, the Brazilian Dysfunctional Voiding Score (DVSS) questionnaire was used. Results: Validation was performed on a sample of 107 children and adolescents with a mean age of 9.2 ± 2.84 years, presenting BBD and 107 without BBD (control group-CG). There was a positive correlation (r = 0.91, 95% CI 0.88 to 0.93, p < 0.0001) between total VSS score and total DVSS score. VSS was higher in patients with BBD (p < 0.0001). The internal consistency estimated by Cronbach's alpha was 0.87 for patients with BBD. The VSS showed excellent diagnostic accuracy in detecting cases, with an area under the ROC curve of 98% (95% CI 0.96 to 0.99, p < 0.001). A cut-off value of >11 points produced a sensitivity of 100% (95% CI 96.4% to 100%) and a specificity of 91.8% (95% CI 85.1% to 95.6%). Conclusion: The translated, cross-culturally adapted, and validated VSS for the Brazilian population is a reliable and valid tool to identify symptoms of BBD in children and adolescents aged five to 16 years, whose first language is Brazilian Portuguese. Objective translate crosscultural cross cultural adaptation (VSS (BBD Methods 1 (1 2 (2 translations 3 (3 backtranslation, backtranslation back back-translation 4 (4 prefinal pre final instrument 5 (5 6 (6 (DVSS used Results 10 92 9 9. 284 84 2.8 years control groupCG. groupCG group CG . group-CG) r 091 0 91 0.91 95 088 88 0.8 093 93 0.93 0.0001 00001 0001 0.0001. Cronbachs Cronbach s 087 87 cases 98 (95 096 96 0.9 099 99 0.99 0.001. 0.001 001 0.001) cutoff cut off 11 >1 100 964 96.4 918 8 91.8 851 85 85.1 95.6%. 956 95.6% 95.6%) Conclusion crossculturally culturally adapted Portuguese ( 28 2. group-CG 09 08 0. 0.000 0000 000 (9 0.00 00 > 96. 91. 85. 95.6 0.0 95.

https://doi.org/10.1590/s1677-5538.ibju.2022.0495

Congenital ocular toxoplasmosis in consecutive siblings
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Silva, Milena Simões F.

; Yamamoto, Aparecida Y.

; Carvalheiro, Cristina G.

; Grigg, Michael E.

; Medeiros, Ana Leonor A. de

; Mussi-Pinhata, Marisa M.

; Furtado, João M.

Arquivos Brasileiros de Oftalmologia

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Dez 2022, Volume 85 Nº 6 Páginas 625 - 628

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO A infecção pelo Toxoplasma gondii pode causar manifestações oculares tanto após a sua forma congênita quanto a sua forma adquirida. Reportamos aqui dois casos de toxoplasmose congênita sintomática com envolvimento ocular em irmãos não gêmeos, com intervalo de 2 anos entre gestações. A transmissão vertical da toxoplasmose em gestações sucessivas, outrora considerada impossível, é um evento plausível mesmo em indivíduos imunocompetentes.

ABSTRACT Toxoplasma gondii infection can cause ocular manifestations after acquired and congenital disease. We report two cases of symptomatic congenital toxoplasmosis with ocular involvement in non-twin siblings, with a 2-year interval between pregnancies. Vertical transmission of toxoplasmosis in successive pregnancies, which was once considered impossible, is now found to be plausible even in immunocompetent subjects.

https://doi.org/10.5935/0004-2749.20220079

Relationship between primary monosymptomatic enuresis and process toilet training: a case-control
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Carvalho, Tânia Antunes

; Vasconcelos, Mônica Maria de Almeida

; Bessa Junior, José de

; Bastos Netto, José Murillo

; Dutra, Melissa Faria

; Guimarães, Isabela Cristina de Oliveira

; Lima, Eleonora Moreira

; Silva, Ana Cristina Simões e

; Mrad, Flávia Cristina de Carvalho

International braz j urol

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Dez 2022, Volume 48 Nº 6 Páginas 944 - 951

Resumo: En | Texto: En | PDF: En

ABSTRACT Objective: Primary monosymptomatic nocturnal enuresis (PMNE) is a prevalent condition in childhood, and the pathophysiology is multifactorial. This study investigated the relationship between the toilet training process (TT) and PMNE in children and adolescents. Patients and Methods: A case-control study was carried out from 2015 to 2020. The presence of PMNE was identified according to International Children's Continence Society criteria. A semi-structured questionnaire was applied to assess TT. Results: The study included 103 children and adolescents with PMNE and 269 participants with normal psychomotor development without PMNE (control group [CG]). Readiness signals were more remembered and less frequent in participants with PMNE (p=0.001) when compared to control group. No differences were found between the groups regarding the onset age of the daytime TT (p= 0.10), the nocturnal TT (p=0.08), the acquisition of daytime continence (p=0.06), and the type of equipment used for the TT (p=0.99). The use of Child-Oriented approach in group of children with enuresis was lower than in controls [87.4% (90/103) versus 94% (250/266)], respectively (OR= 0.44, 95% CI 0.21-0.94, p = 0.039). Conclusions: The age of onset of TT, acquisition of daytime continence, and the type of equipment were not associated with higher occurrence of PMNE. On the other hand, the Child-Oriented approach was a protective factor for the occurrence of PMNE.

https://doi.org/10.1590/s1677-5538.ibju.2022.0381

10.

Risk factors for acute kidney injury after liver transplantation in intensive care unit: a retrospective cohort study
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Neves, Ana Paula Camargos de Figueirêdo

; Gomes, Angélica Gomides dos Reis

; Vassallo, Paula Frizera

; Silva, Ana Cristina Simões e

; Penna, Francisco Guilherme Cancela e

; Bastos, Fabrício de Lima

; Muniz, Mateus Rocha

; Rocha, Guilherme Carvalho

; Santos Júnior, Augusto Cesar Soares dos

; Ravetti, Cecilia Gómez

; Nobre, Vandack

Sao Paulo Medical Journal

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Ago 2022, Volume 140 Nº 4 Páginas 559 - 565

Resumo: En | Texto: En | PDF: En

ABSTRACT BACKGROUND: Acute kidney injury (AKI) is a frequent complication during the postoperative period following liver transplantation. Occurrence of AKI in intensive care unit (ICU) patients is associated with increased mortality and higher costs. OBJECTIVE: To evaluate occurrences of moderate or severe AKI among patients admitted to the ICU after liver transplantation and investigate characteristics associated with this complication. DESIGN AND SETTING: Single-center retrospective cohort study in a public hospital, Belo Horizonte, Brazil. METHODS: Forty-nine patients admitted to the ICU between January 2015 and April 2017 were included. AKI was defined from a modified Kidney Disease Improving Global Outcomes (KDIGO) score (i.e. based exclusively on serum creatinine levels). RESULTS: Eighteen patients (36.7%) developed AKI KDIGO 2 or 3; mostly KDIGO 3 (16 out of the 18 patients). Lactate level within the first six hours after ICU admission (odds ratio, OR: 1.3; 95% confidence interval, CI: 1.021-1.717; P = 0.034) and blood transfusion requirement within the first week following transplantation (OR: 8.4; 95% CI: 1.687-41.824; P = 0.009) were independently associated with development of AKI. Patients with AKI KDIGO 2 or 3 underwent more renal replacement therapy (72.2% versus 3.2%; P < 0.01), had longer hospital stay (20 days versus 15 days; P = 0.001), higher in-hospital mortality (44.4% versus 6.5%; P < 0.01) and higher mortality rate after one year (44.4% versus 9.7%; P = 0.01). CONCLUSION: Need for blood transfusion during ICU stay and hyperlactatemia within the first six postoperative hours after liver transplantation are independently associated with moderate or severe AKI. Developing AKI is apparently associated with poor outcomes.

https://doi.org/10.1590/1516-3180.2021.0641.r2.12112021

11.

Non-surgical management of vesicoureteral junction obstruction: a case report
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Kimura, Thais Yuki

; Castro, Pedro Alves Soares Vaz de

; Silva, Thiago Vasconcelos

; Mesquita, Jordana Almeida

; Silva, Ana Cristina Simões e

Brazilian Journal of Nephrology

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Jun 2022, Volume 44 Nº 2 Páginas 296 - 300

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: Relatar o caso de um paciente pediátrico com hidronefrose bilateral devido à obstrução da junção vesicoureteral (OJVU) que foi tratado não cirurgicamente e discutir a abordagem desta anomalia. Descrição do caso: Um menino de 25 meses de idade foi encaminhado sem queixas para consulta devido à ultrassonografia pré-natal que mostrou rins com cistos. Ele estava sob profilaxia antibiótica. Nenhum histórico familiar de doença renal e/ou distúrbios hereditários foi relatado. A ultrassonografia renal (USR) aos 2 dias de vida mostrou hidronefrose bilateral, descartando assim a possibilidade de doença renal cística. A cintilografia renal dinâmica (DTPA) mostrou uma retenção acentuada do marcador no sistema pielocalicial bilateralmente, com pouca resposta ao diurético. O paciente foi mantido em profilaxia antibiótica, quando uma nova USR apresentou dilatação ureteral bilateral, estenose abrupta na região de transição ureterovesical (calibre 0,2 cm), hidronefrose bilateral moderada e leve espessura cortical renal, confirmando o diagnóstico de OJVU. Aos 2 anos e 10 meses de idade, a DTPA mostrou hidronefrose e estase ureteral em ambos os rins secundárias à estenose no nível da junção vesicoureteral (JVU), com preservação da função renal e grau lento de esvaziamento. Optamos por uma abordagem não cirúrgica. A USR aos 10 anos de idade mostrou melhora significativa de todos os parâmetros, com diâmetro transverso ureteral de 9 mm, JVU preservada, e desenvolvimento renal bilateral adequado à idade. Comentários: A OJVU é uma das principais causas de hidronefrose pré-natal e pode desencadear uma deterioração da função renal. Seu tratamento ainda é controverso, mas deve levar em consideração a importância do acompanhamento clínico e da avaliação seriada por imagem.

Abstract Objective: To report the case of a pediatric patient with bilateral hydronephrosis due to vesicoureteral junction obstruction (VUJO) that was treated non-surgically and to discuss the approach of this anomaly. Case Description: A 25-month-old boy was referred without complaints for consultation due to prenatal ultrasound showing kidneys with cysts. He was under antibiotic prophylaxis. No family history of kidney disease and/or inherited disorders was reported. Renal ultrasound (RUS) at 2 days of life showed bilateral hydronephrosis, thus ruling out the possibility of kidney cystic disease. Dynamic renal scintigraphy (DTPA) showed marked retention of the marker in the pyelocaliceal system bilaterally, with little response to diuretic drug. He was maintained under antibiotic prophylaxis, when a new RUS showed bilateral ureteral dilatation, abrupt stenosis in the ureterovesical transition region (0.2 cm caliber), moderate bilateral hydronephrosis, and slight renal cortical thickness, confirming the diagnosis of VUJO. At 2 years and 10 months of age, DTPA showed hydronephrosis and ureteral stasis in both kidneys secondary to stenosis at the vesicoureteral junction (VUJ) level, with preservation of kidney function and slow degree of emptying. We opted for a non-surgical approach. RUS at 10 years of age showed significant improvement of all parameters, with ureteral transverse diameter of 9 mm, preserved VUJ, and age-appropriate bilateral kidney development. Comments: VUJO is a major cause of prenatal hydronephrosis and can trigger a deterioration of kidney function. Its treatment is still controversial but should take into account the importance of clinical follow-up and serial imaging evaluation.

https://doi.org/10.1590/2175-8239-jbn-2020-0152

12.

Renin angiotensin system molecules and chemokine (C-C motif) ligand 2 (CCL2) in chronic kidney disease patients
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Schettini, Isabella Viana Gomes

; Faria, Débora Vargas

; Nogueira, Leilismara Sousa

; Otoni, Alba

; Silva, Ana Cristina Simões e

; Rios, Danyelle Romana Alves

Brazilian Journal of Nephrology

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Mar 2022, Volume 44 Nº 1 Páginas 19 - 25

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Introdução: Estudos têm mostrado que o sistema renina angiotensina aldosterona (SRAA) e a inflamação estão relacionados à progressão da lesão renal. O objetivo deste estudo foi avaliar moléculas do SRAA e o Ligante 2 de Quimiocina com Motivo C-C (CCL2) em 82 pacientes com doença renal crônica (DRC). Métodos: Os pacientes foram divididos em dois grupos: pacientes diagnosticados com DRC e pacientes sem diagnóstico de DRC. Foram determinadas a taxa de filtração glomerular (TFG) e a relação albumina/creatinina (RAC), assim como os níveis plasmáticos de angiotensina-(1-7) [Ang-(1-7)], enzima conversora de angiotensina (ECA)1, ECA2 e níveis plasmáticos e urinários de CCL2. Resultados: Os níveis plasmáticos de CCL2 foram significativamente mais altos em pacientes com DRC em comparação com o grupo controle. Pacientes com TFG mais baixa apresentaram níveis plasmáticos mais elevados de ECA2 e CCL2 e menor relação ECA1/ECA2. Pacientes com valores de RAC mais altos apresentaram níveis plasmáticos de ECA1 mais elevados. Conclusão: Pacientes com DRC mostraram maior atividade de ambos os eixos do SRAA, o clássico e o alternativo, e níveis plasmáticos mais altos de CCL2. Portanto, os níveis plasmáticos de moléculas do SRAA e CCL2 parecem ser marcadores prognósticos promissores e até mesmo alvos terapêuticos para a DRC.

Abstract Introduction: Studies have shown that the renin angiotensin aldosterone system (RAAS) and inflammation are related to kidney injury progression. The aim of this study was to evaluate RAAS molecules and chemokine (C-C motif) ligand 2 (CCL2) in 82 patients with chronic kidney disease (CKD). Methods: Patients were divided into two groups: patients diagnosed with CKD and patients without a CKD diagnosis. Glomerular filtration rate (GFR) and albumin/creatinine ratio (ACR) were determined, as well as plasma levels of angiotensin-(1-7) [Ang-(1-7)], angiotensin-converting enzyme (ACE)1, ACE2, and plasma and urinary levels of CCL2. Results: CCL2 plasma levels were significantly higher in patients with CKD compared to the control group. Patients with lower GFR had higher plasma levels of ACE2 and CCL2 and lower ratio ACE1/ACE2. Patients with higher ACR values had higher ACE1 plasma levels. Conclusion: Patients with CKD showed greater activity of both RAAS axes, the classic and alternative, and higher plasma levels of CCL2. Therefore, plasma levels of RAAS molecules and CCL2 seem to be promising prognostic markers and even therapeutic targets for CKD.

https://doi.org/10.1590/2175-8239-jbn-2021-0030

13.

Global scientific production in the pre-Covid-19 Era: An analysis of 53 countries for 22 years
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OLIVEIRA, EDUARDO A.

; OLIVEIRA, MARIA CHRISTINA L.

; COLOSIMO, ENRICO A.

; MARTELLI, DANIELLA B.

; SILVA, LUDMILA R.

; SILVA, ANA CRISTINA SIMÕES E

; MARTELLI-JÚNIOR, HERCÍLIO

Anais da Academia Brasileira de Ciências

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2022, Volume 94 elocation e20201428

Resumo: En | Texto: En | PDF: En

Abstract Based on an extensive analysis of public databases, we provide an overview of the global scientific output and describe the dynamics of the profound changes in the scientific enterprise during the last decades. The analysis included the scientific production of 53 countries over the 1996-2018 period. During this period, the production of articles per year has tripled. There was a strong correlation between the growth of the global gross domestic product and the increase in the number of articles (R2 = 0.973, P<0.001). Six countries showed a robust increment of their scientific production and are currently among the top 20 in the ranking of world scientific production (China, India, South Korea, Brazil, Turkey, and Iran). The mean annual growth rate was about 12.7% for these six countries. The share of the global scientific production of these countries increased from 7% in 1996 to 27.8% in 2018. Conversely, the participation of the 10 most traditional countries has dropped from 73% to 45% during the same period. In conclusion, we believe that our findings may contribute to further studies aiming to evaluate the impact and changes of the scientific endeavor over the next years in light of the forthcoming new world framework.

https://doi.org/10.1590/0001-3765202220201428

14.

A case study of an adolescent according to A Model of Children’s Adjustment to Parental Cancer
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Sousa, Ana Filipa Domingues

; Santos, Diana Gabriela Simões Marques

; Costeira, Cristina Raquel Baptista

; Ferreira, Maria Margarida da Silva Reis dos Santos

; Lomba, Maria de Lurdes Lopes de Freitas

Revista da Escola de Enfermagem da USP

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2022, Volume 56 elocation e20220188

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: descrever e analisar experiência de um adolescente a vivenciar cancro parental, fundamentado no Modelo Teórico do Ajuste dos Adolescentes ao Cancro Parental, e prescrever intervenções de enfermagem em linguagem classificada. Método: estudo de caso único, tipo qualitativo, de adolescente de 16 anos de idade a vivenciar cancro da mãe. Analisou-se uma entrevista semiestruturada, baseada em um roteiro concetualizado pelo modelo teórico selecionado. Tratamento de dados ocorreu através de análise de conteúdo. Obteve-se autorização da Comissão de Ética TI 25/2020. Resultados: a análise da entrevista do adolescente permitiu identificar categorias concordantes com as variáveis do modelo. As dimensões de ajuste psicossocial e sintomas de resposta ao estress, como performance acadêmica e sintomas somáticos, foram reconhecidas no processo de ajuste do adolescente. As intervenções de enfermagem serão focadas na educação e apoio. Conclusão o modelo teórico contribuiu para avaliar as necessidades do adolescente a vivenciar cancro parental, permitindo prescrever intervenções de enfermagem em linguagem classificada que considerem variáveis moderadoras e mediadoras, promovendo-se o ajuste. O modelo demonstrou ser adequado para futuras intervenções a adolescentes a experienciar situações semelhantes.

ABSTRACT Objective: To describe and analyze the experience of an adolescent experiencing parental cancer, based on A Model of Children’s Adjustment to Parental Cancer, and to prescribe nursing interventions in classified language. Method: This is a single case study, qualitative, of a 16-year-old adolescent experiencing maternal cancer. We analyzed a semi-structured interview, based on a script conceptualized by the selected theoretical model. Data processing took place through content analysis. Authorization was obtained from the Research Ethics Committee TI 25/2020. Results: The analysis of the adolescent’s interview allowed identifying categories in agreement with the model variables. Psychosocial adjustment dimensions and stress response symptoms, such as academic performance and somatic symptoms, were recognized in the adolescent’s adjustment process. Nursing interventions will focus on education and support. Conclusion: The theoretical model contributed to assess the needs of adolescents experiencing parental cancer, allowing nursing interventions to be prescribed in classified language that consider moderating and mediating variables, promoting adjustment. The model proved to be suitable for future interventions for adolescents experiencing similar situations.

RESUMEN Objetivo: Describir y analizar la experiencia de un adolescente con cáncer en los padres, a partir del Modelo Teórico de Adaptación del Adolescente al Cáncer en los Padres, y prescribir intervenciones de enfermería en lenguaje clasificado. Método: Estudio de caso único, cualitativo, de una adolescente de 16 años con cáncer materno. Se analizó una entrevista semiestructurada, a partir de un guión conceptualizado por el modelo teórico seleccionado. El procesamiento de datos se llevó a cabo a través del análisis de contenido. Se obtuvo autorización del Comité de Ética TI 25/2020. Resultados: El análisis de la entrevista adolescente permitió la identificación de categorías de acuerdo con las variables del modelo. En el proceso de ajuste del adolescente se reconocieron dimensiones de ajuste psicosocial y síntomas de respuesta al estrés, como rendimiento académico y síntomas somáticos. Las intervenciones de enfermería se centrarán en la educación y el apoyo. Conclusión: El modelo teórico contribuyó para evaluar las necesidades de los adolescentes que experimentan cáncer en los padres, permitiendo que las intervenciones de enfermería sean prescritas en un lenguaje clasificado que considere variables moderadoras y mediadoras, promoviendo el ajuste. El modelo demostró ser adecuado para futuras intervenciones con adolescentes en situaciones similares.

https://doi.org/10.1590/1980-220x-reeusp-2022-0188en

15.

EXPERIENCING PARENTAL CANCER: A CASE STUDY WITH APPLICATION OF NEUMAN’S MODEL
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Sousa, Ana Filipa Domingues

; Santos, Diana Gabriela Simões Marques

; Costeira, Cristina Raquel Baptista

; Ferreira, Maria Margarida da Silva Reis dos Santos

; Lomba, Maria de Lurdes Lopes de Freitas

Texto & Contexto - Enfermagem

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2022, Volume 31 elocation e20220201

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo compreender à luz do Modelo de Sistemas de Betty Neuman, a experiência de uma mulher-mãe a vivenciar uma situação de cancro; identificar as necessidades da mulher-mãe e prescrever intervenções de enfermagem em linguagem classificada. Método estudo de caso do tipo qualitativo, de uma mulher-mãe de um adolescente, a vivenciar cancro. Colheita de dados realizada em Coimbra, Portugal, em 2021, através de entrevista semiestruturada, apoiada por um guião fundamentado no Modelo de Betty Neuman. Tratamento de dados realizado com base na análise de conteúdo categorial. Resultados a análise do discurso da mãe possibilitou identificar categorias concordantes com as variáveis do modelo: fisiológicas, psicológicas, socioculturais, espirituais e desenvolvimentais. As dificuldades mais expressas pela mãe foram o medo, alterações provocadas pela doença e o desempenho do papel parental. Os diagnósticos de enfermagem foram definidos com base nos focos “aceitação do estado de saúde”, “medo”, “papel parental” e “coping familiar”, associando-os às respetivas intervenções de enfermagem. As intervenções focaram-se no apoio e na educação. Conclusão o modelo teórico contribuiu para compreender e identificar as necessidades da mãe a experienciar o cancro parental, facilitando a prescrição de intervenções de enfermagem em linguagem classificada. O modelo mostrou-se pertinente para futuras intervenções em pais a vivenciar situações semelhantes.

ABSTRACT Objective to understand, in the light of Betty Neuman’s Systems Model, the experience of a woman-mother with cancer, and identify the woman-mother’s needs and prescribe nursing interventions in classified language. Method a qualitative case study of a woman-mother of a teenager experiencing cancer. Data collection carried out in Coimbra, Portugal, in 2021, through a semi-structured interview, supported by a script based on Betty Neuman’s Systems Model. Data processing performed based on categorical content analysis. Results the analysis of a mother’s speech made it possible to identify categories in agreement with the model variables: physiological, psychological, sociocultural, spiritual and developmental. The difficulties most expressed by the mother were fear, changes caused by the disease and parental role performance. The nursing diagnoses were defined based on the focuses “acceptance of health status”, “fear”, “parental role” and “family coping”, associating them with the respective nursing interventions. Interventions focused on support and education. Conclusion the theoretical model contributed to understanding and identifying the needs of a mother experiencing parental cancer, facilitating the prescription of nursing interventions in classified language. The model proved to be relevant for future interventions in parents experiencing similar situations.

RESUMEN Objetivo comprender, a la luz del Modelo de Sistemas de Betty Neuman, la experiencia de una mujer-madre que vive una situación de cáncer, e identificar las necesidades de la mujer-madre y prescribir intervenciones de enfermería en lenguaje clasificado. Método estudio de caso cualitativo de una mujer-madre de un adolescente en proceso de cáncer. Recopilación de datos realizada en Coimbra, Portugal, en 2021, a través de una entrevista semiestructurada, apoyada en un guión basado en el Modelo Betty Neuman. El procesamiento de datos fue realizado en base al análisis de contenido categórico. Resultados el análisis del discurso de la madre permitió identificar categorías de acuerdo con las variables del modelo: fisiológicas, psicológicas, socioculturales, espirituales y de desarrollo. Las dificultades más expresadas por la madre fueron el miedo, los cambios provocados por la enfermedad y el desempeño del rol parental. Los diagnósticos de enfermería fueron definidos a partir de los enfoques “aceptación del estado de salud”, “miedo”, “rol de los padres” y “afrontamiento familiar”, asociándolos a las respectivas intervenciones de enfermería. Las intervenciones centradas en el apoyo y la educación. Conclusión el modelo teórico contribuyó a la comprensión e identificación de las necesidades de las madres con cáncer parental, facilitando la prescripción de intervenciones de enfermería en lenguaje clasificado. El modelo demostró ser relevante para futuras intervenciones en padres que experimentan situaciones similares.

https://doi.org/10.1590/1980-265x-tce-2022-0201en

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Glossário e ajuda para busca

Você pode enriquecer sua busca de uma forma muito simples. Use os índices de pesquisa combinados com os conectores (AND ou OR) e especifique cada vez mais sua busca.

Por exemplo, se você deseja buscar artigos sobre
casos de dengue no Brasil em 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

Veja abaixo a lista completa de índices de pesquisa que podem ser usados:

Cód. do Índice	Elemento
ti	título do artigo
au	autor
kw	palavras-chave do artigo
subject	assunto (palavras do título, resumo e palavras-chave)
ab	resumo
ta	título abreviado da revista (ex. Cad. Saúde Pública)
journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

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Email: scielo@scielo.org

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