Abstract This work sought to understand race, gender, income, and housing inequalities of users of bike--sharing systems in the cities of São Paulo and Rio de Janeiro. A face-to-face sample survey was carried out and the obtained data were compared with data from the two cities concerning the above-mentioned social markers. The results show that the systems are more accessible to some groups, such as women and black people, and less accessible to others, such as low-income people, and that, despite being in urban centers, they manage to maintain the inclusion of groups that do not live in the region. Based on the results, the insertion of these systems in Brazilian cities is discussed. race gender income bikesharing bike sharing Janeiro facetoface face abovementioned above mentioned markers people others lowincome low centers region discussed

Resumo Este trabalho buscou compreender as desigualdades de raça, gênero, renda e moradia dos usuários dos sistemas de compartilhamento de bicicleta nas cidades de São Paulo e do Rio de Janeiro. Uma pesquisa amostral presencial (survey) foi feita e os dados obtidos foram comparados com os dados das cidades em relação aos marcadores sociais mencionados. Os resultados mostram que os sistemas são mais acessíveis para alguns grupos, como mulheres e pessoas negras, e menos acessíveis para outros, como pessoas de baixa renda, e, apesar de estarem localizados nos centros urbanos, conseguem manter a inclusão de grupos que não moram nessa região. A partir dos resultados, foi feita uma discussão sobre a inserção desses sistemas nas cidades brasileiras. raça gênero Janeiro survey (survey mencionados negras outros urbanos região brasileiras

Resumo Fundamento A pandemia da COVID-19 representa uma enorme carga para o sistema de saúde do mundo. Apesar de pacientes pediátricos terem sido relativamente poupados em comparação a adultos, estudos recentes mostraram um número crescente de pacientes críticos com Síndrome Inflamatória Multisistêmica Pediátrica (SIM-P) com disfunção cardiovascular importante. No entanto, pouco se conhece a respeito da relação entre anormalidades cardíacas e biomarcadores inflamatórios e de coagulação. Objetivos Investigar anormalidades ecocardiográficas em pacientes pediátricos com COVID-19 admitidos em um hospital terciário. Métodos Este foi um estudo longitudinal retrospectivo, baseado na revisão de prontuários médicos e ecocardiogramas de pacientes (0-19 anos) admitidos em um hospital terciário entre 30 de março e 30 de junho de 2020. Para a análise estatística, o nível de significância foi estabelecido em 5% (p<0,05). Resultados Foram incluídos 48 pacientes, 73% com doenças pré-existentes, 20 (41,7%) com SIM-P. A idade mediana foi 7,5 (0-18,6) anos; 27 (56,2%) eram do sexo masculino. A duração mediana de internação foi 15,4 (2-92) dias e sete (14,6%) pacientes morreram. Um total de 70 ecocardiografias foram realizadas, 66,7% submeteram-se ao exame somente uma vez, e 33,3% várias vezes. Vinte e três (48%) pacientes apresentaram anormalidades no ecocardiograma: oito (16.6%) disfunção sistólica do ventrículo esquerdo, seis (12.5%) disfunção sistólica do ventrículo direito, e 12 (25%) dilatação da artéria coronária (Z-score>+2,5). Anormalidades ecocardiográficas foram significativamente associadas com SIM-P, admissão na unidade de terapia intensiva pediátrica, suporte ventilatório/vasoativo, e morte ( p <0,05). Níveis significativamente mais altos de d-dímero (ng/mL) foram detectados em pacientes com disfunção ventricular esquerda [16733(4157-115668) vs. 2406.5(190-95040)], disfunção ventricular direita [25769(3422-115668) vs. 2803.5(190-95040)] e dilatação da artéria coronária [9652.5(921-115668) vs. 2724(190- 95040)] (p<0,05). Conclusão Anormalidades ecocardiográficas eram frequentes nos pacientes pediátricos com COVID-19 e associadas com piores desfechos clínicos. Exacerbação das vias de inflamação e coagulação pode exercer um importante papel na lesão cardiovascular nesses pacientes.

Abstract Background COVID-19 pandemic represents a huge burden to the health system in the world. Although pediatric COVID-19 patients have been relatively spared compared with adults, recent reports showed an increasing number of critically ill patients with multisystemic inflammatory syndrome in children (MIS-c), with marked cardiovascular impairment. Nevertheless, little is known about the relationship between cardiac abnormalities and inflammatory and coagulation biomarkers. Objectives to investigate echocardiographic abnormalities in pediatric patients with COVID-19 admitted to tertiary hospital. Methods this was a retrospective longitudinal study, based on the review of medical records and echocardiograms of patients (0-19 years) admitted to a tertiary hospital between March 30 and June 30, 2020. For statistical analysis, the significance level was set at 5% (p < 0.05). Results Forty-eight patients were enrolled, 73% with preexisting diseases, 20 (41.7%) with MIS-c. Median age was 7.5 (0-18.6) years; 27 (56.2%) were male. Median duration of hospitalization was 15.4 (2-92) days and seven (14.6%) patients died. A total of 70 echocardiograms were performed; 66.7% patients were scanned only once and 33.3% multiple times. Twenty-three (48%) patients showed echocardiographic abnormalities: eight (16.6%) left ventricle (LV) systolic dysfunction, six (12.5%) right ventricle (RV) systolic dysfunction and 12 (25%) coronary dilatation (Z-score>+2.5). Echocardiographic abnormalities were significantly associated with MIS-c, admission to the pediatric intensive care unit, multiple organ dysfunction, ventilatory/vasoactive support, and death (p<0.05). Significantly higher d-dimer (ng/mL) levels were detected in patients with LV dysfunction [16733(4157-115668) vs. 2406.5(190-95040)], RV dysfunction [25769(3422-115668) vs. 2803.5(190-95040)] and coronary artery dilation [9652.5(921-115668) vs. 2724(190- 95040)] (p<0.05). Conclusion Echocardiographic abnormalities in COVID-19 pediatric patients were frequent and associated with worse clinical outcomes. Exacerbation of the inflammation and coagulation pathways may play an important role in cardiovascular injury in those patients.

ABSTRACT The objective of this study was to evaluate the effect of lipid sources on voluntary intake, digestibility, performance, and CH4 emission of Nellore steers grazing Brachiaria brizantha cv. Xaraés forage in the dry season. Forty-five Nellore steers with average weight of 442±34 kg were alloted into one of the five treatments: without additional fat; with palm oil; with linseed oil; with protected fat; and with whole soybeans. The supplements were provided daily and quantities were adjusted to 1% of body weight and diets were formulated in accordance with the Cornell Net Carbohydrate and Protein System. The experimental design was completely randomized with five treatments and two replications. There were no effects on dry matter, organic matter, and neutral detergent fiber intake with the inclusion of lipids in the diet. The neutral detergent fiber showed decreased digestibility in animals receiving linseed oil and palm oil treatments compared with animals receiving the diet without additional fat. The linseed oil treatment reduced CH4 emissions by 38% when expressed in mg/d/kg BW and tended to reduce the emission in g/d/kg BW0.75. Lipid sources did not affect the weight gain of the animals. The intake and performance of grazing Nellore steers supplemented at 1% body weight with lipid sources were not modified. However, fiber digestibility was reduced with palm or linseed oil addition. Linseed oil reduced enteric CH4 emissions. Linseed oil has the potential to reduce enteric CH4 emissions in continuous tropical grazing systems based on B. brizantha grass.

The objective of this study was to evaluate the characteristics of ruminal fermentation and enteric methane production in beef cattle subjected to different supplementation frequencies while grazing on Brachiaria brizanthacv. Marandu pastures. Nine cattle (325±65.7 kg BW) fitted with ruminal and duodenal cannulas were used in the ruminal fermentation study, and 12 cattle (399±32.6 kg BW) were used in the enteric methane production study. The treatments included supplementation once daily, supplementation once daily except Saturdays and Sundays, or supplementation on alternate days. The supplementation was equivalent to 10 g kg−1 BW day−1 for all treatments. The design employed was completely randomized with three treatments and three replications. When all supplements were provided (day 1), no effects of supplementation frequency were observed on ruminal pH; concentration of NH3-N; concentration of acetic, propionic, or butyric acids; or total volatile fatty acids (VFA), but there were month effects. During the day on which only daily supplements were provided (day 2), significant differences were observed only on the molar concentration of acetic acid and total VFA; and month effects were noted on all variables. No significant differences were observed in ruminal fluid volume, dilution rate, N intake, bacterial N synthesis and enteric methane production among the studied supplementation frequencies. Differences were observed in the enteric methane production in the different months, with 85 g kg−1 of gross energy intake observed in September and 123 g kg−1 of gross energy intake observed in November. Lower supplementation frequency is a good option to lower labor costs with little or no consequences on ruminal fermentation characteristics and enteric methane production.