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ABSTRACT The physical fitness perception of college students refers to how they see themselves in terms of their physical condition and health. In this stage, anthropometric variables may be affected by stress, changes in sleep and eating habits, and decreased participation in physical activities, impacting academic performance and general health. The objective of this study is to relate the perception of physical condition with self-reported anthropometric measures in university students. This is a descriptive-correlational, observational, cross-sectional research. Forty-six university students from the city of Talca were evaluated. Physical condition was measured by means of the International Fitness Scale (IFIS) and anthropometric measures by means of self-report. General physical condition was inversely related to waist circumference (r=-0.32; p=0.028), waist circumference (r=-0.44; p=0.002) and IFIS (r=-0.43; p=0.003). Inverse correlations were observed between cardiorespiratory fitness with BMI (p=0.008; r=-0.38), waist circumference and ECI (p=0.008; r=-0.38). Speed/agility was inversely correlated with body mass index (BMI) (p=0.001; r=-0.46), waist circumference (p=0.019; r=-0.34), hip (p= 0.004; r= -0.40) and ECI (p=0.004; r=-0.41). Flexibility was inversely correlated with BMI (p=0.041; r=-0.30), waist circumference (p=0.023; r=-0.33), waist hip index (WHI) (p= 0.001; r=-0.45)). Lastly, muscle was not correlated with the anthropometric variables. It is concluded that there is an inverse correlation between the perception of physical condition and some anthropometric measures.

RESUMO A percepção da aptidão física em estudantes universitários refere-se a como eles se veem em termos de sua condição física e saúde. Nessa fase, as variáveis antropométricas podem ser afetadas pelo estresse, por mudanças nos hábitos de sono e alimentação e pela diminuição da participação em atividades físicas, o que afeta o desempenho acadêmico e a saúde em geral. O objetivo foi relacionar a percepção da aptidão física com medidas antropométricas autorreferidas em estudantes universitários. Trata-se de uma pesquisa descritiva, correlacional, transversal e observacional. Foram avaliados 46 estudantes universitários da cidade de Talca. A condição física foi medida por meio da Escala Internacional de Aptidão Física (IFIS) e as medidas antropométricas por meio de autorrelato. A aptidão física geral foi inversamente relacionada à circunferência da cintura (r=-0,32; p=0,028), circunferência da cintura (r=-0,44; p=0,002) e IFIS (r=-0,43; p=0,003). Foram observadas correlações inversas entre a aptidão cardiorrespiratória com o IMC (p=0,008; r=-0,38), a circunferência da cintura e o ECI (p=0,008; r=-0,38). A velocidade/agilidade foi inversamente correlacionada com o índice de massa corporal (IMC) (p=0,001; r=-0,46), circunferência da cintura (p=0,019; r=-0,34), quadril (p= 0,004; r= -0,40) e ECI (p=0,004; r=-0,41). A flexibilidade foi inversamente correlacionada com o IMC (p=0,041; r=-0,30), a circunferência da cintura (p=0,023; r=-0,33), o índice cintura-quadril (WHI) (p= 0,001; r=-0,45). Por fim, a musculatura não foi correlacionada com as variáveis antropométricas. Concluise que há uma correlação inversa entre a percepção da condição física e algumas medidas antropométricas.

RESUMEN La percepción de la condición física en estudiantes universitarios se refiere a cómo se ven a sí mismos en términos de su estado físico y salud. En esta etapa, las variables antropométricas pueden verse afectadas por estrés, cambios en hábitos de sueño y alimentación, y menor participación en actividades físicas, impactando el desempeño académico y salud general. El objetivo fue relacionar la percepción de la condición física con medidas antropométricas auto reportadas en estudiantes universitarios Esta Investigación es de tipo descriptivo-correlacional, de diseño observacional y corte transversal. Fueron evaluados 46 estudiantes universitarios de la ciudad de Talca. La condición física se midió por medio del International Fitness Scale (IFIS) y las medidas antropométricas por medio de auto reporte. La condición física general se relacionó de manera inversa con la circunferencia de cintura (r=-0,32; p=0,028), la circunferencia de cintura(r=-0,44; p=0,002) y el ICE (r=-0,43; p=0,003). Se observaron correlaciones inversas entre la condición cardiorrespiratoria con el IMC (p=0,008; r=-0,38), circunferencia de cintura e ICE (p=0,008; r=-0,38). La velocidad/agilidad se correlacionó de forma inversa con el índice de masa corporal (IMC) (p=0,001; r=-0,46), circunferencia de cintura (p=0,019; r=-0,34), cadera (p= 0,004; r= -0,40) y el ICE (p=0,004; r=-0,41). La flexibilidad se correlaciono de forma inversa con el IMC (p=0,041; r=-0,30), circunferencia de cintura (p=0,023; r=-0,33), índice cintura cadera (ICC) (p= 0,001; r=-0,45)). Por último, la fuera muscular no se correlaciono con las variables antropométricas. Se concluye que existe correlación inversa entre la percepción de la condición física y algunos autore portes de las medidas antropométricas.

https://doi.org/10.29035/rcaf.25.1.2

Influence of feedlot living space on production variables, carcass and meat quality traits in Holstein steers
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Romo-Valdez, Ana Mireya

; Pérez-Linares, Cristina

; Ríos-Rincón, Francisco Gerardo

; Figueroa-Saavedra, Fernando

; Barreras-Serrano, Alberto

; Castro-Pérez, Beatriz Isabel

; Sánchez-López, Eduardo

; Cervantes Cazarez, Georgina Valentina

Revista mexicana de ciencias pecuarias

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Jun 2024, Volume 15 Nº 2 Páginas 393 - 403

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract A determination of how the amount of allotted feedlot living space influences both production indicators as well as carcass and meat quality traits obtained from Holstein steers was performed by forming two treatment groups, T14: 65 steers/pen (14 m2/head of space allowances) and T16: 57 steers/pen (16 m2/head of space allowances), with five replications each treatment. The average arrival weight 238 ± 0.74 kg. During the fattening period the cattle was feed twice a day with commercial diets. The steers were slaughtered after a 261-d period. At the moment of the first reimplant a greater average body weight was found in T16 vs T14 (384.25 vs 378.38 kg; P<0.05) and the difference continued until day 261 (612.35 vs 595.54 kg; P<0.05); regarding ADG, hot carcass weight and cold carcass weight the result were: 1.50 vs 1.46 kg (P<0.05), of ADG kg/d; 367.34 vs 360.35 kg (P<0.05) and 366.68 vs 358.78 kg (P<0.05). No difference between treatments were found in dorsal fat, marbling, pH and meat color. The results suggest that an increase from 14 m2/animal to 16 m2/animal improves the production results as well as the hot and cold carcass weight, with no effect on the quality traits of the carcass and beef.

Resumen Se determinó cómo la cantidad de espacio vital asignado en el corral de engorda, influye tanto en los indicadores de producción como en los rasgos de calidad de la canal y la carne obtenidas de novillos Holstein mediante la formación de dos grupos de tratamiento, T14: 65 novillos/corral (14 m2/cabeza de espacio permitido) y T16: 57 novillos/corral (16 m2/cabeza de espacio permitido), con cinco repeticiones en cada tratamiento. El peso promedio de llegada fue de 238 ± 0.74 kg. Durante el período de engorda el ganado se alimentó dos veces al día con dietas comerciales. Los novillos se sacrificaron después de un período de 261 días. En el momento del primer reimplante se encontró un mayor peso corporal promedio en T16 vs T14 (384.25 vs 378.38 kg; P<0.05) y la diferencia se mantuvo hasta el día 261 (612.35 vs 595.54 kg; P<0.05); en cuanto a la GDP, el peso de la canal caliente y el peso de la canal fría, los resultados fueron: 1.50 vs 1.46 kg (P<0.05), de GDP kg/día; 367.34 vs 360.35 kg (P<0.05) y 366.68 vs 358.78 kg (P<0.05). No se encontraron diferencias entre los tratamientos en la grasa dorsal, el marmoleado, el pH y el color de la carne. Los resultados sugieren que un aumento de 14 m2/animal a 16 m2/animal mejora los resultados productivos, así como el peso de la canal caliente y fría, sin afectar a los rasgos de calidad de la canal y la carne.

https://doi.org/10.22319/rmcp.v15i2.6449

Coronavirus disease-2019 and heart: assessment of troponin and cardiovascular comorbidities as prognostic markers in patients hospitalized with coronavirus disease-2019 in a tertiary center in Brazil disease2019 disease 2019 disease-201 heart disease201 201 disease-20 disease20 20 disease-2 disease2 2 disease-
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Pinesi, Henrique Trombini

; Giugni, Fernando Rabioglio

; Matuck, Bruna Romanelli Scarpa

; Pitta, Fabio Grusnpun

; Garzillo, Cibele Larrosa

; Lima, Eduardo Gomes

; Kalil Filho, Roberto

; Serrano Junior, Carlos Vicente

Revista da Associação Médica Brasileira

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2023, Volume 69 Nº 7 elocation e20230350

Resumo: En | Texto: En | PDF: En

SUMMARY OBJECTIVE: Our study aimed to evaluate the correlation of cardiac troponin T levels with comorbidities and in-hospital outcomes in patients with coronavirus disease-2019 in Brazil. METHODS: Data from a cohort of 3,596 patients who were admitted with suspected coronavirus disease-2019 in a Brazilian tertiary center, between March and August 2020, were reviewed. A total of 2,441 (68%) patients had cardiac troponin T determined in the first 72 h of admission and were stratified into two groups: elevated cardiac troponin T (cardiac troponin T >0.014 ng/mL) and normal cardiac troponin T. Associations between troponin, comorbidities, biomarkers, and outcomes were assessed. Regression models were built to assess the association of several variables with in-hospital mortality. RESULTS: A total of 2,441 patients were embraced, of which 924 (38%) had normal cardiac troponin T and 1,517 (62%) had elevated cardiac troponin T. Patients with elevated cardiac troponin T were older and had more comorbidities, such as cardiovascular disease, hypertension, diabetes, arrhythmia, renal dysfunction, liver disease, stroke, cancer, and dementia. Patients with abnormal cardiac troponin T also had more altered laboratory parameters on admission (i.e., leukocytes, C-reactive protein, D-dimer, and B-type natriuretic peptide), as well as more need for intensive care unit, vasoactive drugs, mechanical ventilation, dialysis, and blood transfusion. All-cause mortality was markedly higher among patients with increased cardiac troponin T (42 vs. 16%, P<0.001). Multiple regression analysis demonstrated that in-hospital mortality was not independently associated with troponin elevation. CONCLUSION: This study showed that cardiac troponin T elevation at admission was common and associated with several comorbidities, biomarkers, and clinical outcomes in patients hospitalized with coronavirus disease-2019, but it was not an independent marker of in-hospital mortality. OBJECTIVE inhospital hospital disease2019 disease 2019 disease-201 Brazil METHODS 3596 3 596 3,59 center 2020 reviewed 2441 2 441 2,44 68% 68 (68% 7 groups 0014 0 014 >0.01 ng/mL ngmL ng mL biomarkers assessed RESULTS embraced 92 38% 38 (38% 1517 1 517 1,51 62% 62 (62% hypertension diabetes arrhythmia dysfunction stroke cancer dementia i.e., ie i e (i.e. leukocytes Creactive C reactive protein Ddimer, Ddimer D dimer, dimer D-dimer Btype B type peptide, peptide , peptide) unit drugs ventilation dialysis transfusion Allcause All cause 42 (4 vs 16 16% P<0.001. P0001 P P<0.001 . 001 P<0.001) CONCLUSION disease2019, 2019, disease201 201 disease-20 359 59 3,5 202 244 44 2,4 6 (68 01 >0.0 9 (38 151 51 1,5 (62 i.e. (i.e 4 ( P000 P<0.00 00 disease20 20 disease-2 35 5 3, 24 2, (6 >0. (3 15 1, i.e P00 P<0.0 disease2 disease- >0 P0 P<0. > P<0 P<

https://doi.org/10.1590/1806-9282.20230350

Acompanhamento de Dois Anos de Pacientes com Cardiopatia Isquêmica Crônica em um Centro Especializado no Brasil
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Moreira, Eduardo Martelli

; Pinesi, Henrique Trombini

; Martins, Eduardo Bello

; Pitta, Fábio Grunspun

; Bolta, Paula Mathias Paulino

; Segre, Carlos Alexandre Wainrober

; Favarato, Desiderio

; Rached, Fabiana Hanna

; Hueb, Whady Armindo

; Lima, Eduardo Gomes

; Kalil Filho, Roberto

; Garzillo, Cibele Larrosa

; Serrano Jr, Carlos Vicente

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 Nº 10 elocation e20220440

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background The incidence of cardiovascular events in patients with chronic ischemic heart disease (CIHD) may vary significantly among countries. Although populous, Brazil is often underrepresented in international records. Objectives This study aimed to describe the quality of care and the two-year incidence of cardiovascular events and associated prognostic factors in CIHD patients in a tertiary public health care center in Brazil. Methods Patients with CIHD who reported for clinical evaluation at Instituto do Coração (São Paulo, Brazil) were registered and followed for two years. The primary endpoint was a composite of myocardial infarction (MI), stroke, or death. A significance level of 0.05 was adopted. Results From January 2016 to December 2018, 625 participants were included in the study. Baseline characteristics show that 33.1% were women, median age 66.1 [59.6 – 71.9], 48.6% had diabetes, 83.1% had hypertension, 62.6% had previous MI, and 70.4% went through some revascularization procedure. At a median follow-up (FU) of 881 days, we noted 37 (7.05%) primary endpoints. After adjustments, age, previous stroke, and LDL-cholesterol were independently associated with the primary endpoint. Comparing baseline versus FU, participants experienced relief of angina based on the Canadian Cardiovascular Society (CCS) scale according to the following percentages: 65.7% vs. 81.7% were asymptomatic and 4.2% vs. 2.9% CCS 3 or 4 (p < 0.001). They also experienced better quality of medication prescription: 65.8% vs. 73.6% (p < 0.001). However, there was no improvement in LDL-cholesterol or blood pressure control. Conclusion This study shows that CIHD patients had a two-year incidence of the primary composite endpoint of 7.05%, and the reduction of LDL-cholesterol was the only modifiable risk factor associated with prognosis. (CIHD countries populous records twoyear year São Paulo years MI , (MI) stroke death 005 0 05 0.0 adopted 201 2018 62 331 33 1 33.1 women 661 66 66. 59.6 596 59 6 [59. 71.9, 719 71.9 71 9 71.9] 486 48 48.6 diabetes 831 83 83.1 hypertension 626 62.6 704 70 70.4 procedure followup follow up FU (FU 88 days 7.05% 705 7 (7.05% endpoints adjustments LDLcholesterol LDL cholesterol (CCS percentages 657 65 65.7 vs 817 81 81.7 42 2 4.2 29 2.9 p 0.001. 0001 0.001 . 001 0.001) prescription 658 8 65.8 736 73 73.6 However control prognosis (MI 00 0. 20 33. 59. 5 [59 71. 48. 83. 62. 70. 7.05 (7.05 65. 81. 4. 2. 000 0.00 73. [5 7.0 (7.0 [ 7. (7. (7 (

Resumo Fundamento A incidência de eventos cardiovasculares em pacientes com doença cardíaca isquêmica crônica (DCIC) pode variar significativamente entre os países. Embora populoso, o Brasil é frequentemente sub-representado nos registros internacionais. Objetivos Este estudo teve como objetivo descrever a qualidade do atendimento e a incidência de eventos cardiovasculares em dois anos, além de fatores prognósticos associados em pacientes com DCIC em um centro terciário de saúde pública no Brasil. Métodos Pacientes com DCIC que compareceram para avaliação clínica no Instituto do Coração (São Paulo, Brasil) foram cadastrados e acompanhados por dois anos. O desfecho primário foi um composto de infarto do miocárdio (IM), acidente vascular encefálico ou morte. Um nível de significância de 0,05 foi adotado. Resultados De janeiro de 2016 a dezembro de 2018, 625 participantes foram incluídos no estudo. As características basais mostram que 33,1% eram mulheres, a idade mediana era de 66,1 [59,6 – 71,9], 48,6% tinham diabetes, 83,1% tinham hipertensão, 62,6% tinham IM prévio e 70,4% passaram por algum procedimento de revascularização. Em um acompanhamento mediano de 881 dias, 37 (7,05%) desfechos primários foram observados. Após ajustes, idade, acidente vascular encefálico prévio e colesterol LDL foram independentemente associados ao desfecho primário. Comparando a linha de base com o acompanhamento, os participantes relataram alívio da angina com base na escala da Sociedade Cardiovascular Canadense (SCC) de acordo com as seguintes porcentagens: 65,7% vs. 81,7% eram assintomáticos e 4,2% vs. 2,9% eram SCC 3 ou 4 (p < 0,001). Eles também relataram melhor qualidade na prescrição de medicamentos: 65,8% vs. 73,6% (p < 0,001). No entanto, não houve melhora no colesterol LDL ou no controle da pressão arterial. Conclusão O presente estudo mostra que pacientes com DCIC apresentaram uma incidência de 7,05% do desfecho primário composto em um período de dois anos, sendo a diminuição do colesterol LDL o único fator de risco modificável associado ao prognóstico. (DCIC países populoso subrepresentado sub representado internacionais anos São Paulo IM, , (IM) morte 005 0 05 0,0 adotado 201 2018 62 331 33 1 33,1 mulheres 661 66 66, 59,6 596 59 6 [59, 71,9, 719 71,9 71 9 71,9] 486 48 48,6 diabetes 831 83 83,1 hipertensão 626 62,6 704 70 70,4 revascularização 88 dias 705 7 (7,05% observados ajustes (SCC porcentagens 657 65 65,7 vs 817 81 81,7 42 2 4,2 29 2,9 p 0,001. 0001 0,001 . 001 0,001) medicamentos 658 8 65,8 736 73 73,6 entanto arterial 7,05 prognóstico (IM 00 0, 20 33, 59, 5 [59 71, 48, 83, 62, 70, (7,05 65, 81, 4, 2, 000 0,00 73, 7,0 [5 (7,0 7, [ (7, (7 (

https://doi.org/10.36660/abc.20220440

Code infarction initiative of Bajio region, during the pandemic by COVID-19 in a reconversion hospital
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Villar-Valencia, Cristian Adrián

; Hernández-González, Martha Alicia

; Borrayo-Sánchez, Gabriela

; Celis-Quintal, Juan German

; Solorio-Meza, Sergio Eduardo

; Medina-Torres, Oscar Samuel

; Gutiérrez-Galván, Maraí Xochitl

; Rodríguez-Martínez, Braulio

; Prado-Rodríguez, Luis Humberto

; Vázquez-Morones, Ana Laura

; Alatoma-Medina, Juan Pablo

; Hernández-Estala, Jorge

; Patiño-Amaya, Aristóteles

; Magdaleno-Serrano, Hugo Ivan

; Rodríguez-Déniz, Carmen

; Arellano-Sotelo, Hugo

; Nava-Hernández, Guillermo

; Ramírez-Vázquez, Ricardo

; Chimal-Flores, Marco Antonio

; Alegría-Peredia, Emiliano

; Ramos-González, Gerardo Rubén

; Pérez-Benítez, Rigoberto

; Bermúdez-Acévez, Erik

; Valencia-Martínez, Hypatia

; Segovia-Solís, Hugo

; López-Varela, Manuel

; Monroy-Córdoba, Doryan

; Marmolejo-López, Adriana

; Báez-Montes, Alfredo

; Hernández-Cerqueda, Fabián

; Nolasco-Muñoz, Luis Ricardo

; Vargas-Ramírez, Luis Manuel

; Celis-Quintal, Juan German

; Bernal-Ruíz, Enrique Alfredo

; Delgado-Sánchez, Anabella

; Sánchez-López, José Manuel

; Bautista-López, Germán Ramón

; Acevedo-Gómez, Pablo Francisco

; Acuña-Valerio, Jorge Francisco

; González-Ortíz, Oracio

; Hernández-Padilla, Adolfo Asahel

; Solórzano-Vázquez, Marco Alejandro

; Franco-Herrera, Noel

; González, Luis Jonathan

; Reyes-Álvarez, José Miguel

; Salinas-Cavazos, Iván Rosendo

; Tiscareño-Villanueva, Ashby Daniel

; Vidrio-Villaseñor, Ramiro

; Fernández-Yáñez, Gabriel

; Meza, Ma. Guadalupe

; Nucamendi-Solórzano, Freeman Issac

; Sandoval-Uribe, José de Jesús

; Sotelo-García, Luis David

; Zamoaya-Paz, Luis Carlos

; Espriu, Donovan Fernando

; García-Rodríguez, Román

; López-Ibarra, Daniel Eugenio

; López-Valencia, Andrea Janeth

; Villar-Valencia, Cristian Adrián

; Navarro-Pérez-Macedo, Javier

Cardiovascular and metabolic science

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Set 2022, Volume 33 Nº 3 Páginas 97 - 105

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract: Introduction: Acute myocardial infarction has a high prevalence and possibility of death if timely care is not given. It is possible that treatment could be delayed during a health crisis such as the COVID-19 pandemic. Objective: The objective of this study was to evaluate the impact of the COVID-19 pandemic on the function of the infarction code in the High Specialty Medical Unit of our institution. The medical indicators of acute coronary ischemic syndrome with ST-segment elevation were compared at two times: before the COVID-19 pandemic and during it. Material and methods: An ambispective, analytical, comparative cohort study was conducted, comparing the periods of February-September 2019 and February-September 2020, in the High Specialty Medical Unit, Centro Médico del Bajío number 1, Instituto Mexicano del Seguro Social, Leon, Guanajuato, Mexico. All patients older than 18 years with clinical, electrocardiographic, and enzymatic data of acute coronary ischemic syndrome, accepted in the medical network as infarction code registered in the National Registry of Acute Coronary Ischemic Syndromes (RENASCA) electronic case report form were included in the study. Results: The independent samples t-test was used to determine the impact of the infarction code initiative based on the reperfusion therapies performed, the door-to-needle, the door-to-balloon time, and the ischemia time. There was a significant difference in the reperfusion strategy, with greater thrombolysis during the COVID-19 pandemic (57.4% versus 72.6%, odds ratio [OR] 1.97, 95% confidence interval [CI] 0.49-0.82, p < 0.001), as well as reperfusion criteria (21.03% versus 35.37%, OR 2.05, 95% CI 0.53-0.80, p < 0.0001). Mortality was not different between the time periods. Conclusions: The COVID-19 pandemic has not impacted operation of the infarction code in the High Specialty Medical Unit Centro Médico del Bajío number 1 because the medical indicators of acute coronary ischemic syndrome with ST-segment elevation did not change.

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https://doi.org/10.35366/107622

Desempenho Diagnóstico da Angiotomografia Computadorizada e da Avaliação Seriada de Troponina Cardíaca Sensível em Pacientes com Dor Torácica e Risco Intermediário para Eventos Cardiovasculares
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Soeiro, Alexandre de Matos

; Biselli, Bruno

; Leal, Tatiana C.A.T.

; Bossa, Aline Siqueira

; César, Maria Cristina

; Jallad, Sérgio

; Goldstein, Priscila Gherardi

; Guimarães, Patrícia Oliveira

; Serrano Jr, Carlos Vicente

; Nomura, Cesar Higa

; Nakamura, Débora

; Rochitte, Carlos Eduardo

; Soares, Paulo Rogério

; Oliveira Jr., Múcio Tavares de

Arquivos Brasileiros de Cardiologia

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Mai 2022, Volume 118 Nº 5 Páginas 894 - 902

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Fundamento A angiotomografia coronária (ATC) tem sido usada para avaliação de dor torácica principalmente em pacientes de baixo risco, e poucos dados existem com pacientes em risco intermediário. Objetivo Avaliar o desempenho de medidas seriadas de troponinas sensíveis e de ATC em pacientes de risco intermediário. Métodos Um total de 100 pacientes com dor torácica, TIMI score 3 ou 4 e troponina negativa foram prospectivamente incluídos. Todos os pacientes foram submetidos à ATC, e aqueles com obstruções ≥ 50% foram encaminhados à cineangiocoronariografia. Pacientes com lesões < 50% recebiam alta hospitalar, receberam alta e foram contatados 30 dias depois por telefonema para avaliação dos desfechos clínicos. Os desfechos foram hospitalização, morte, e infarto agudo do miocárdio em 30 dias. A comparação entre os métodos foi realizada pelo teste de concordância kappa. O desempenho das medidas de troponina e da ATC na detecção de lesões coronárias significativas e desfechos clínicos foi calculado. Os resultados foram considerados estatisticamente significativos quando p <0,05. Resultados Estenose coronária ≥ 50% na ATC foi encontrada em 38% dos pacientes e lesões coronárias significativas na angiografia coronária foram encontradas em 31 pacientes. Dois eventos clínicos foram observados. A análise de concordância Kappa mostrou baixa concordância entre as medidas de troponina e ATC na detecção de lesões coronárias significativas (kappa = 0,022, p = 0,78). O desempenho da ATC para detectar lesões coronárias significativas na angiografia coronária ou para prever eventos clínicos em 30 dias foi melhor que as medidas de troponina sensível (acurácia de 91% versus 60%). Conclusão ATC teve melhor desempenho que as medidas seriadas de troponina na detecção de doença coronariana significativa em pacientes com dor torácica e risco intermediário para eventos cardiovasculares.

Abstract Background Coronary tomography angiography (CTA) has been mainly used for chest pain evaluation in low-risk patients, and few data exist regarding patients at intermediate risk. Objective To evaluate the performance of serial measures of sensitive troponin and CTA in intermediate-risk patients. Methods A total of 100 patients with chest pain, TIMI risk scores of 3 or 4, and negative troponin were prospectively included. All patients underwent CTA and those with coronary stenosis ≥ 50% were referred to invasive coronary angiography. Patients with coronary lesions <50% were discharged and contacted 30 days later by a telephone call to assess clinical outcomes. Outcomes were hospitalization, death, and myocardial infarction at 30 days. The comparison between methods was performed by Kappa agreement test. The performance of troponin measures and CTA for detecting significant coronary lesions and clinical outcomes was calculated. Results were considered statistically significant when p < 0.05. Results Coronary stenosis ≥ 50% on CTA was found in 38% of patients and significant coronary lesions on coronary angiography were found in 31 patients. Two clinical events were observed. Kappa agreement analysis showed low agreement between troponin measures and CTA in the detection of significant coronary lesions (kappa = 0.022, p = 0.78). The performance of CTA for detecting significant coronary lesions on coronary angiography or for predicting clinical events at 30 days was better than sensitive troponin measures (accuracy of 91% versus 60%). Conclusion CTA performed better than sensitive troponin measures in the detection of significant coronary disease in patients with chest pain and intermediate risk for cardiovascular events.

https://doi.org/10.36660/abc.20210006

Root canal microbiota as an augmented reservoir of antimicrobial resistance genes in type 2 diabetes mellitus patients
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VÁZQUEZ-RAMOS, Víctor Rafael

; PÉREZ-SERRANO, Rosa Martha

; GARCÍA-SOLÍS, Pablo

; SOLÍS-SAINZ, Juan Carlos

; ESPINOSA-CRISTÓBAL, León Francisco

; CASTRO-RUÍZ, Jesús Eduardo

; DOMÍNGUEZ-PÉREZ, Rubén Abraham

Journal of Applied Oral Science

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2022, Volume 30 elocation e20220362

Resumo: En | Texto: En | PDF: En

Abstract Antimicrobial resistance is a global public health problem. Root canal microbiota associated with apical periodontitis represents a well-known reservoir of antimicrobial resistance genes (ARGs). However, the effect of type 2 diabetes mellitus (T2DM) in this reservoir is unknown. This study aimed to establish if root canal microbiota associated with apical periodontitis in T2DM patients is an augmented reservoir by identifying the prevalence of nine common ARGs and comparing it with the prevalence in nondiabetic patients. Methodology This cross-sectional study included two groups: A T2DM group conformed of 20 patients with at least ten years of living with T2DM and a control group of 30 nondiabetic participants. Premolar or molar teeth with pulp necrosis and apical periodontitis were included. A sample was collected from each root canal before endodontic treatment. DNA was extracted, and ARGs were identified by polymerase chain reaction. Results tetW and tetM genes were the most frequent (93.3 and 91.6%, respectively), while ermA was the least frequent (8.3%) in the total population. The distribution of the ARGs was similar in both groups, but a significant difference (p<0.005) was present in ermB, ermC, cfxA, and tetQ genes, being more frequent in the T2DM group. A total of eighty percent of the T2DM patients presented a minimum of four ARGs, while 76.6% of the control group presented a maximum of three. Conclusions Root canal microbiota associated with apical periodontitis in T2DM patients carries more ARGs. Therefore, this pathological niche could be considered an augmented reservoir. problem wellknown well known . (ARGs) However TDM T DM (T2DM unknown crosssectional cross sectional groups 3 participants treatment extracted reaction 93.3 933 93 (93. 916 91 6 91.6% respectively, respectively , respectively) 8.3% 83 8 (8.3% population p<0.005 p0005 p 0 005 (p<0.005 ermB ermC cfxA 766 76 76.6 three Therefore (ARGs 93. 9 (93 91.6 8.3 (8.3 p<0.00 p000 00 (p<0.00 7 76. (9 91. 8. (8. p<0.0 p00 (p<0.0 ( (8 p<0. p0 (p<0. p<0 (p<0 p< (p< (p

https://doi.org/10.1590/1678-7757-2022-0362

Manejo con dispositivo Watchman en un paciente con fibrilación auricular y en terapia de diálisis. Reporte de caso y revisión narrativa
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Rosselli Sanmartín, Carlos

; Torres Serrano, Rodolfo Eduardo

; Olivares Algarin, Orlando

; Olivares Algarin, Carlos Roberto

; Eslava Orozco, David Felipe

; Nuñez Pinilla, Edwin Reynaldo

; Pérez Morales, Hugo Enrique

Revista Colombiana de Nefrología

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Dez 2020, Volume 7 Nº 2 Páginas 104 - 112

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen La anticoagulación es la terapia de elección para la mayoría de pacientes con fibrilación auricular no valvular; sin embargo, en pacientes con enfermedad renal crónica con alto riesgo de sangrado se deben considerar terapias antitrombóticas locales como el cierre percutáneo de la orejuela izquierda con dispositivo Watchman. A continuación, se reporta el primer caso de implante de este dispositivo llevado a cabo en el Hospital de San José de Bogotá, Colombia, y se hace una revisión narrativa sobre este tema. El uso del dispositivo Watchman se asocia con menos accidentes cerebrovasculares hemorrágicos (0,15 vs. 0,96 eventos / 100 pacientes-año HR=0,22; p=0,004), menos muertes cardiovasculares o inexplicadas (1,1 vs. 2,3 eventos / 100 paciente-año; HR=0,48; p=0,006) y menos casos de sangrado no asociado al procedimiento (6,0 % vs. 11,3 %; HR=0,51; p=0,006) en comparación con la warfarina.

Resumen Anticoagulation remains the therapy of choice for the majority of patients with non-valvular atrial fibrillation, however, in patients with chronic kidney disease at high risk of bleeding, local antithrombotic therapies such as the left atrial closure with Watchman device should be considered. We report the first case of implant of this type device in the Hospital de San José at the City of Bogotá, Colombia, and a narrative review of the literature is made. Watchman's use is associated with fewer hemorrhagic strokes (0.15 versus 0.96 events / 100 patients-year HR: 0.22; p = 0.004), cardiovascular death / unexplained death (1.1 vs. 2.3 events / 100 patient-year; HR: 0.48; p = 0.006), and bleeding not associated with the procedure (6.0 % vs. 11.3 %; HR: 0.51; p = 0.006) compared to warfarin.

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Prognostic Differences between Men and Women with Acute Coronary Syndrome. Data from a Brazilian Registry
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Soeiro, Alexandre de Matos

; Silva, Pedro Gabriel Melo de Barros e

; Roque, Eduardo Alberto de Castro

; Bossa, Aline Siqueira

; Biselli, Bruno

; Leal, Tatiana de Carvalho Andreucci Torres

; Soeiro, Maria Carolina Feres de Almeida

; Pitta, Fábio Grunspun

; Serrano Jr., Carlos V.

; Oliveira Jr., Múcio Tavares

Arquivos Brasileiros de Cardiologia

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Nov 2018, Volume 111 Nº 5 Páginas 648 - 653

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Fundamento: Existem diferenças relatadas entre pacientes com síndrome coronariana aguda, de acordo com o sexo. A descrição deste achado comparativo em registro brasileiro ainda não foi documentada. Objetivo: Comparar pacientes do sexo masculino vs. feminino quanto a características basais, achados coronarianos, tratamento e prognóstico intra-hospitalar e em longo prazo. Métodos: Trata-se de estudo retrospectivo, multicêntrico e observacional, no qual foram incluídos 3.745 pacientes (2.437 do sexo masculino e 1.308 do sexo feminino) entre maio de 2010 e maio de 2015. O desfecho primário intra-hospitalar foi mortalidade por todas as causas. O desfecho secundário foi eventos combinados (choque cardiogênico, reinfarto, morte, acidente vascular cerebral e sangramento). A comparação entre grupos foi realizada por meio de qui-quadrado e teste t, sendo considerado significativo p < 0,05. Em longo prazo, foram avaliados a mortalidade e os eventos combinados pelo método Kaplan-Meier, com seguimento médio de 8,79 meses. Resultados: A média de idade foi de 60,3 anos no sexo masculino e 64,6 no feminino (p < 0,0001). O fator de risco mais prevalente foi hipertensão arterial sistêmica em 72,9% das mulheres e 67,8% nos homens (p = 0,001). Intervenção coronária percutânea foi realizada em 44,9% no sexo masculino e 35,4% no feminino (p < 0,0001), e revascularização miocárdica cirúrgica em 17% no sexo masculino e 11,8% no feminino (p < 0,0001), com maior prevalência de padrão coronariano triarterial no sexo masculino (27,3% vs. 16,2%; p < 0,0001). Cerca de 79,9% dos pacientes do sexo feminino enquadraram-se no diagnóstico de síndrome coronariana aguda sem supradesnivelamento do segmento ST, enquanto no sexo masculino este número foi de 71,5% (p < 0,0001). Em curto e longo prazos não se observaram diferenças significativas entre os grupos, tanto em mortalidade quanto em eventos combinados. Conclusão: Observaram-se múltiplas diferenças relacionadas ao sexo em pacientes com síndrome coronariana aguda no que se refere a características demográficas, padrão coronariano e tratamento adotado. No entanto, a evolução prognóstica foi semelhante entre os grupos.

Abstract Background: Gender-related differences have been reported in patients with acute coronary syndrome. The description of this comparative finding in a Brazilian registry has not yet been documented. Objective: To compare male vs. female patients regarding the baseline characteristics, coronary findings, treatment and in-hospital and long-term prognosis. Methods: This is a retrospective, multicenter and observational study that included 3,745 patients (2,437 males and 1,308 females) between May 2010 and May 2015. The primary in-hospital outcome was all-cause mortality. The secondary outcome consisted of combined events (cardiogenic shock, reinfarction, death, stroke and bleeding). The comparison between groups was performed using the chi-square and the t test, considering p < 0.05 as significant. In the long term, mortality and combined events were assessed using the Kaplan-Meier method, with a mean follow-up of 8.79 months. Results: The mean age was 60.3 years for males and 64.6 for females (p < 0.0001). The most prevalent risk factor was systemic arterial hypertension in 72.9% of the women and 67.8% of the men (p = 0.001). Percutaneous coronary intervention was carried out in 44.9% of the males and 35.4% of the females (p < 0.0001), and coronary artery bypass grafting (CABG) was performed in 17% of the males and 11.8% of females (p < 0.0001), with a higher prevalence of three-vessel coronary artery disease in males (27.3% vs. 16.2%, p < 0.0001). Approximately 79.9% of the female patients received a diagnosis of acute coronary syndrome without ST-segment elevation, while in the male patients, this diagnosis was attained in 71.5% (p < 0.0001). No significant differences were observed between the groups in the short and long term, regarding both mortality and the combined events. Conclusion: Several gender-related differences were observed in patients with acute coronary syndrome regarding the demographic characteristics, coronary artery disease pattern and implemented treatment. However, the prognostic evolution was similar between the groups.

https://doi.org/10.5935/abc.20180166 1757 downloads

10.

Estimación de la concentración de clorofila mediante métodos no destructivos en vid (Vitis vinifera L.) cv. Riesling Becker
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CASTAÑEDA, CRISTIAN SANTIAGO

; ALMANZA-MERCHÁN, PEDRO JOSÉ

; PINZÓN, ELBERTH HERNANDO

; CELY-REYES, GERMÁN EDUARDO

; SERRANO-CELY, PABLO ANTONIO

Revista Colombiana de Ciencias Hortícolas

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Ago 2018, Volume 12 Nº 2 Páginas 329 - 337

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN El análisis de pigmentos en plantas es un procedimiento de laboratorio y comúnmente no es una medida inmediata que se realice in situ. El SPAD 502 y CCM-200 son equipos para estimar de modo indirecto, no destructivo y rápido el contenido de clorofila. La concentración de pigmentos fotosintéticos se relaciona con la concentración foliar de nitrógeno, por lo que de forma indirecta se puede conocer la deficiencia o exceso del elemento, puede servir como fundamento técnico para sugerir el manejo adecuado del cultivo, en busca de potencializar la eficiencia fotosintética, calidad y el rendimiento de un viñedo. La investigación buscó comparar las mediciones entre el medidor portátil de clorofila SPAD-502 y CCM-200, en la variedad de uva Riesling Becker, bajo condiciones de clima frío tropical, y con ello determinar el comportamiento de clorofila durante el crecimiento de las hojas 4, 5 y 6, desde floración hasta vendimia. La relación entre las mediciones con el SPAD-502 y el CCM-200 se ajustaron a un polinomio de segundo grado determinado por la ecuación, para el Índice de Concentración de Clorofila, como ICC = 0,014SPAD2-0,2396SPAD + 5,8021. Con un valor de R 2=0,9343 (n = 96; P ≤0,0001), el cual indica que existe una alta correlación entre los equipos portátiles empleados en el presente estudio para determinar la clorofila de forma no destructiva. Las evaluaciones realizadas con los equipos permitieron obtener medidas rápidas y confiables. Siendo importante la elección del momento de medición de acuerdo con el estadio fenológico de la planta debido a la alta variabilidad en los contenidos de clorofila que se presentan en relación a la filotaxia.

ABSTRACT Pigment analysis is a laboratory procedure and is not an immediate measurement to be performed in situ. The SPAD 502 and CCM-200 are equipments used for non-destructive, fast, and indirect estimates of chlorophyll contents. The concentration of photosynthetic pigments is related to the foliar concentration of nitrogen, so indirectly, it is possible to observe the deficiency or excess of this element, providing a technical basis to suggest the proper management of the crop in order to potentiate the photosynthetic efficiency, quality and yield of a vineyard. This research sought to compare measurements between the portable chlorophyll meter SPAD-502 vs. CCM-200 in the Riesling Becker grape variety under cold tropical climate conditions to determine the behavior of chlorophyll during the growth of leaves 4, 5 and 6, from flowering to harvest. The relationship between the measurements with the SPAD-502 and the CCM-200 were fit to a second degree polynomial determined with the equation for the Chlorophyll Concentration Index: CCI = 0.014SPAD2-0.2396SPAD + 5.8021. With a value of R 2 = 0.9343 (n = 96; P≤0.0001), which indicates that there was a high correlation between the portable equipment used in the present study to determine chlorophyll with a non-destructive method. The evaluations carried out with the equipment obtained fast and reliable measurements, with the choice of the moment of measurement according to the pheno-logical stage of the plant being important because of the high variability in chlorophyll contents that are presented in relation to the phylotaxy.

https://doi.org/10.17584/rcch.2018vl2i2.7566 810 downloads

11.

Heart Failure with Preserved Left Ventricular Ejection Fraction in Patients with Acute Myocardial Infarction
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Antonelli, Lucas

; Katz, Marcelo

; Bacal, Fernando

; Makdisse, Marcia Regina Pinho

; Correa, Alessandra Graça

; Pereira, Carolina

; Franken, Marcelo

; Fava, Anderson Nunes

; Serrano Junior, Carlos Vicente

; Pesaro, Antonio Eduardo Pereira

Arquivos Brasileiros de Cardiologia

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Ago 2015, Volume 105 Nº 2 Páginas 145 - 150

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Fundamento: A prevalência e os desfechos clínicos em pacientes com insuficiência cardíaca com fração de ejeção do ventrículo esquerdo preservada pós-infarto agudo do miocárdio ainda não foram bem elucidados. Objetivo: Analisar a prevalência de insuficiência cardíaca com fração de ejeção do ventrículo esquerdo preservada no infarto agudo do miocárdio e sua associação com a mortalidade. Métodos: Pacientes com infarto agudo do miocárdio (n = 1.474) foram incluídos prospectivamente. Pacientes admitidos sem insuficiência cardíaca (Killip = 1), com insuficiência cardíaca com fração de ejeção do ventrículo esquerdo preservada (Killip > 1 e fração de ejeção do ventrículo esquerdo ≥ 50%) e com insuficiência cardíaca sistólica (Killip > 1 e fração de ejeção do ventrículo esquerdo < 50%) foram comparados. A associação entre insuficiência cardíaca sistólica e com fração de ejeção do ventrículo esquerdo preservada, com a mortalidade hospitalar foi testada em modelos ajustados. Resultados: Dentre os incluídos, 1.256 (85,2%) pacientes foram admitidos sem insuficiência cardíaca (72% homens, 67 ± 15 anos), 78 (5,3%) com insuficiência cardíaca com fração de ejeção do ventrículo esquerdo preservada (59% homens, 76 ± 14 anos) e 140 (9,5%) com insuficiência cardíaca sistólica (69% homens, 76 ± 14 anos), com mortalidade, respectivamente, de 4,3; 17,9 e 27,1% (p < 0,001). A regressão logística (ajustada para sexo, idade, troponina, diabetes e índice de massa corporal) demonstrou que insuficiência cardíaca com fração de ejeção do ventrículo esquerdo preservada (odds ratio de 2,91; intervalo de confiança de 95% de 1,35-6,27; p = 0,006) e insuficiência cardíaca sistólica (odds ratio de 5,38; intervalo de confiança de 95% de 3,10-9,32; p < 0,001) se associaram à mortalidade intra-hospitalar. Conclusão: Um terço dos pacientes com infarto agudo do miocárdio admitidos com insuficiência cardíaca apresentou fração de ejeção do ventrículo esquerdo preservada. Apesar de esse subgrupo ter evolução mais favorável que os pacientes com insuficiência cardíaca sistólica, ele apresentou risco de morte três vezes maior do que o grupo sem insuficiência cardíaca. Pacientes com infarto agudo do miocárdio e insuficiência cardíaca com fração de ejeção do ventrículo esquerdo preservada apresentaram elevado risco em curto prazo e mereceram especial atenção e monitorização durante a internação hospitalar.

Abstract Background: The prevalence and clinical outcomes of heart failure with preserved left ventricular ejection fraction after acute myocardial infarction have not been well elucidated. Objective: To analyze the prevalence of heart failure with preserved left ventricular ejection fraction in acute myocardial infarction and its association with mortality. Methods: Patients with acute myocardial infarction (n = 1,474) were prospectively included. Patients without heart failure (Killip score = 1), with heart failure with preserved left ventricular ejection fraction (Killip score > 1 and left ventricle ejection fraction ≥ 50%), and with systolic dysfunction (Killip score > 1 and left ventricle ejection fraction < 50%) on admission were compared. The association between systolic dysfunction with preserved left ventricular ejection fraction and in-hospital mortality was tested in adjusted models. Results: Among the patients included, 1,256 (85.2%) were admitted without heart failure (72% men, 67 ± 15 years), 78 (5.3%) with heart failure with preserved left ventricular ejection fraction (59% men, 76 ± 14 years), and 140 (9.5%) with systolic dysfunction (69% men, 76 ± 14 years), with mortality rates of 4.3%, 17.9%, and 27.1%, respectively (p < 0.001). Logistic regression (adjusted for sex, age, troponin, diabetes, and body mass index) demonstrated that heart failure with preserved left ventricular ejection fraction (OR 2.91; 95% CI 1.35–6.27; p = 0.006) and systolic dysfunction (OR 5.38; 95% CI 3.10 to 9.32; p < 0.001) were associated with in-hospital mortality. Conclusion: One-third of patients with acute myocardial infarction admitted with heart failure had preserved left ventricular ejection fraction. Although this subgroup exhibited more favorable outcomes than those with systolic dysfunction, this condition presented a three-fold higher risk of death than the group without heart failure. Patients with acute myocardial infarction and heart failure with preserved left ventricular ejection fraction encounter elevated short-term risk and require special attention and monitoring during hospitalization.

https://doi.org/10.5935/abc.20150055 2505 downloads

12.

Factores asociados a lesiones músculo-esqueléticas por carga en trabajadores hospitalarios de la ciudad de Torreón, Coahuila, México
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Rivera Guillén, Mario A

; Sanmiguel Salazar, Maria F

; Serrano Gallardo, Luis B

; Nava Hernández, Martha P

; Moran Martínez, Javier

; Figuerola Chaparro, Luis C

; Mendoza Mireles, Eduardo E

; García Salcedo, José J

Ciencia & trabajo

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Ago 2015, Volume 17 Nº 53 Páginas 144 - 149

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Objective: To identify musculoskeletal lesions while lifting-related factors in hospital workers and lifting. Methods: A transversal study was carried out evaluating the prevalence and associated factors to musculoskeletal lesions in 48 workers, using the Nordic Standardized Questionnaire of musculoskeletal symptoms. Results: The mean age was 29.1+6.7 for males and 26.5+6.9 for females. The morning shift had greater activity, Paramedics accounted for the 43.75% and nurses for the 22.92%. Back pain was the most reported symptom among paramedics and auxiliary personnel; nurses reported feet and legs pain. Significant correlations were observed between seniority and the days with pain in the different anatomical regions. 81.9% of the workers do not use safety equipment against back injuries, and 91.67% stated receiving previous training course on lifting activities within the hospital. Conclusions: We evaluated the importance of occupational hygiene within the hospital activities, as well as training of personal safety equipment. The lack of such may be a determining factor that increases days in pain in specific anatomic regions as the working years go by, particularly those pertaining to both upper and lower back.

Objetivo. Identificar factores asociados en la aparición de lesiones músculo-esqueléticas por carga en trabajadores hospitalarios. Métodos. Se aplicó el cuestionario estandarizado nórdico de sintomatologías músculo-esqueléticas con corte transversal que evaluó la frecuencia y factores asociados para las lesiones músculo-esqueléticas en 48 trabajadores. Resultados. La media de edad en hombres fue de 29,1+6,7 y en mujeres 26,5+6,9. El turno matutino tiene mayor actividad laboral. El 43,75% eran paramédicos y el 22,92% enfermeras. La espalda fue la región más afectada en los camilleros y paramédicos; mientras que enfermería reportó más dolor en pies y piernas. Se presentaron correlaciones significativas entre la antigüedad y los días que se presenta el dolor en la región anatómica. El 81,9% no usa equipo de protección contra lesiones en espalda. El 91,67% refirió capacitación previa para desarrollar actividades de cargas dentro del hospital. Conclusiones. Consideramos la importancia de la higiene ocupacional en las actividades hospitalarias y la capacitación del uso del equipo de protección personal en las actividades laborales que se realizan, la falta de uso puede ser uno de los factores determinantes para el incremento en los días con dolor en alguna región anatómica cuando incrementan los años laborables, principalmente lo que corresponde a espalda alta y baja.

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13.

Wavelets infinitamente oscilantes y un eficiente algoritmo de implementación basado en la FFT
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Fabio, Marcela

; Serrano, Eduardo P

Revista de Matemática Teoría y Aplicaciones

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Jun 2015, Volume 22 Nº 1 Páginas 61 - 69

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

En este trabajo presentamos el diseño de una wavelet ortogonal, infinitamente oscilante, localizada en el tiempo con decaimiento 1=jtjn y de banda limitada. Su aplicación conduce a la descomposición de señales en ondas de frecuencia instantánea bien definida. Presentamos además el algoritmo de implementación para el análisis y síntesis basado en la Transformada Rápida de Fourier con la misma complejidad que el algoritmo de Mallat.

In this work we present the design of an orthogonal wavelet, infinitely oscillating, located in time with decay 1=jtjn and limited-band. Its application leads to the signal decomposition in waves of instantaneous, well defined frequency. We also present the implementation algorithm for the analysis and synthesis based on the Fast Fourier Transform (FFT) with the same complexity as Mallat’s algorithm.

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14.

Valor pronóstico de la microalbuminuria en el paciente con infarto agudo del miocardio con elevación del ST
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Serrano-Cuevas, Leonor

; Borrayo-Sánchez, Gabriela

; García-Méndez, Rosalba

; Madrid-Miller, Alejandra

; Almeida-Gutiérrez, Eduardo

Revista mexicana de cardiología

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Mar 2015, Volume 26 Nº 1 Páginas 28 - 33

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Introduction: Microalbuminuria (MA) is an endothelial dysfunction biomarker, and has been associated to higher morbidity and mortality in cardiovascular disease. The ischemic heart disease is among the leading causes of death, and it's necessary to study new risk and prognostic biomarkers in patients with ST-elevation acute myocardial infarction (ST-AMI). Objective: To determine the predict value of microalbuminuria in patients with ST-AMI. Material and methods: We developed an observational, longitudinal, prospective and analytical cohort study, patients older than 18 years old, any sex, within 24 hours evolution ST-AMI were included. Exposed cohort was defined as MA > 20 µg/min in a 24-hour urine sample within 72 hour of myocardial infarction, and were followed for 30 days and cardiovascular events were recorded. Results: We studied 99 patients; 51 (51.5%) presented MA. Basal clinical features were not significantly different. MA subjects had higher APACHE II, TIMI, EUROSCORE and GRACE scores (p < 0.05 for all). Killip-Kimball ≥ III, arrhythmia, advanced atrioventricular block, cardiogenic shock, re-infarction and death were significantly associated to MA (p < 0.05 for all), and this association remains as an independent death predictor adjusted to TIMI and GRACE scores and right ventricle infarction. In the same way, MA is associated with lower survival rate at 30 day, p = 0.002. Conclusions: Microalbuminuria is an independent risk factor for death at 30 days, and should be included as part of biochemical markers in patients with ST elevation acute myocardial infarction.

Introducción: La microalbuminuria (MA) es un marcador de disfunción endotelial, y se ha asociado con mayor morbimortalidad en la enfermedad cardiovascular. En México, las enfermedades isquémicas del corazón ocupan los primeros lugares de mortalidad, por lo que resulta necesario estudiar marcadores que puedan proporcionar pronóstico en los sujetos con síndrome coronario agudo. Objetivo: Determinar el valor pronóstico de la microalbuminuria sobre la evolución de los pacientes con infarto agudo del miocardio con elevación del segmento ST (IAMST). Material y métodos: Estudio de cohorte, observacional, longitudinal, prospectivo y analítico. Se incluyeron pacientes consecutivos con diagnóstico de IAM en las primaras 24 horas de evolución, de cualquier género, mayores de 18 años, que ingresaron a la Unidad de Cuidados Cardiovasculares de un Hospital de Tercer Nivel. Se definió la cohorte expuesta a microalbuminuria en orina de 24 horas (albúmina > 20 µg/min) dentro de las primeras 72 horas de su ingreso, y se dio seguimiento a 30 días registrando la presentación de eventos cardiovasculares. Resultados: Se estudiaron a 99 pacientes, 51 (51.5%) sujetos presentaron MA. Las características basales no presentaron diferencias significativas. Los pacientes con MA tuvo mayor puntuación de las escalas APACHE II, TIMI, GRACE y EUROSCORE (todos p < 0.05). La presentación de Killip-Kimball ≥ III, arritmias, bloqueo atrioventricular avanzado, choque cardiogénico, reinfarto y muerte, se asociaron significativamente con la presencia de MA (todos p < 0.05), y esta asociación es independiente para la presencia de muerte ajustado para las puntuaciones de TIMI, GRACE y la presencia de infarto ventricular derecho. De la misma manera, los sujetos con IAM portadores de MA tienen una supervivencia significativamente menor que aquellos sin MA, p = 0.002. Conclusiones: La microalbuminuria se asocia de manera independiente con muerte a 30 días, y puede ser un biomarcador a medirse rutinariamente en los pacientes con síndrome coronario agudo con elevación del ST.

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15.

Regularidad local del mercado de índices para la crisis económica de 2008
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- SciELO Analytics

Figliola, Alejandra

; Rosenblatt, Mariel

; Serrano, Eduardo P

Revista de Matemática Teoría y Aplicaciones

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- SciELO Analytics

Jan 2012, Volume 19 Nº 1 Páginas 65 - 78

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Existe evidencia de que señales provenientes de los mercados financieros, tales como índices bursátiles, tasas de interés, variaciones de precios de productos básicos, tienen naturaleza multifractal. En los últimos años se han hecho esfuerzos para relacionar la ineficiencia de los mercados con las características multifractales de sus correspondientes señales. Estas características se resumen en el conocimiento del espectro de singularidades o espectro multifractal que relaciona al conjunto de puntos singulares de la señal con su correspondiente dimensión de Hausdorff. La novedosa aproximación que se propone en este trabajo, para el estudio de la dinámica de los mercados financieros, es el estudio de la evolución de los puntos singulares o exponentes Hölder locales de las series de índices bursátiles, medidos diariamente. Se analizaron los “retornos logarítmicos” de los índices bursátiles de 9 países pertenecientes a mercados desarrollados y 12 pertenecientes a mercados emergentes, desde febrero de 2006 hasta marzo de 2009. El análisis revela que la variación temporal del exponente Hölder puntual refleja la evolución de la crisis y detecta los eventos históricos que se desarrollaron durante este fenómeno, a partir de los valores mínimos del exponente Hölder puntual

There is evidence that signals from financial markets, such as stock indices, interest rates or commodities, have a multifractal nature. In recent years, many efforts have been made to relate the inefficiency of markets with the multifractal characteristics of this corresponding signals. These characteristics are summarized in the knowledge of the spectrum of singularities or multifractal spectrum that relates to the set of singular points of the signal with its corresponding Hausdorff dimension. The novel approach proposed in this paper, to study the dynamics of financial markets, is to analyze the evolution of the set of singular points or Hölder exponents of the series of exchanges, measured daily. We examined the “logarithmic returns” of stock indices from 9 countries in developed markets and 12 belonging to emerging markets from February 2006 to March 2009. The analysis reveals that the temporal variation of the local Hölder exponent point reflects the evolution of the crisis and identifies the historical events which have occurred during this phenomenon, from the minimum values of the Hölder exponent

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