Abstract Background In 1839, the Escola de Farmácia de Ouro Preto pioneered the teaching of pharmaceutical sciences in Brazil. At the end of the 19th century, the Escola de Farmácia possessed a French collection of anatomical models, some made of wax and paper-mâché. The models were a critical part of teaching anatomy, particularly in an era of paradigm changes about how the human brain works. Objective The present study aimed to anatomically describe the brain models through a comparative analysis with the current anatomical description. Methods Comparative analysis of the brain models with modern anatomical descriptions. Results In the individual analysis of the wax models, we verified excellent anatomical accuracy of the cortical and subcortical regions. Our results identified internal structures, like the basal ganglia and white matter. Compared with modern anatomical books and websites, the wax brain models have high scientific quality. Conclusion The models of the present study gave students hands-on experience of human anatomy in the 19th century. Nowadays, the models are part of the memory of Universidade Federal de Ouro Preto and Museu da Pharmacia de Ouro Preto. The collection of wax models shows the appreciation of neuroanatomy teaching at the turn of the century concomitant with advances in neurology and anatomy around the world. 1839 Brazil th papermâché. papermâché paper mâché. mâché paper-mâché works description descriptions regions structures matter websites quality handson hands on Nowadays world 183 18 1

Resumo Antecedentes No Brasil, em 1839, a Escola de Farmácia foi pioneira no ensino das ciências farmacêuticas. No final do século XIX, a Escola de Farmácia possuía uma coleção de modelos anatômicos franceses, muitos fabricados em cera e papel machê. A coleção da Escola de Farmácia é muito importante pois faz parte de um período crítico do ensino de neuroanatomia, particularmente em um período de mudanças de paradigmas relacionados às funções do cérebro humano. Objetivo Os objetivos do presente estudo foram analisar anatomicamente os modelos de cérebro e identificar e descrever as estruturas anatômicas com base na descrição anatômica moderna. Métodos Foi feita uma análise comparativa dos modelos com a descrição anatômica moderna. Resultados Na análise individual dos modelos de cera, nós constatamos uma excelente fidelidade anatômica de regiões corticais e subcorticais. Nossos resultados identificaram estruturas internas, como núcleos cerebrais e substância branca. Comparado com livros e páginas da internet sobre anatomia, os modelos de cera apresentam alta qualidade científica. Conclusão Os modelos do presente estudo são importantes, pois ajudam a compreender o ensino de anatomia no século XIX. Atualmente, os modelos fazem parte da memória da Escola de Farmácia de Ouro Preto e do Museu da Pharmacia. A coleção de modelos de cera representa a valorização do ensino de neuroanatomia no final do século XIX em concordância com os avanços da neurologia e neuroanatomia ao redor do mundo. Brasil 1839 farmacêuticas franceses machê humano moderna subcorticais internas branca científica importantes Atualmente Pharmacia mundo 183 18 1

ABSTRACT The rice stem bug, Tibraca limbativentris Stal (Hem.: Pentatomidae), is one of the main insect pests in Brazilian rice crops. Knowledge of its spatiotemporal distribution can support the development of an effective sampling system and improve IPM strategies. This study aimed to map the spatiotemporal distribution of rice stem bug in flooded rice crop in Southern Brazil. Flooded rice crop was scouted for two seasons to estimate insect densities. Four occurrence categories were observed: no insect, only adults, only nymphs, and both phases. The relationship between phenological stages and insect categories was established. Interpolation (mapping) of occurrence categories of T. limbativentris was performed by multiquadric equations. In two seasons during the rice cycle, the results indicate that rice stem bug “adults" were the most abundant category until the mid-vegetative phase of the rice; “nymphs" were the most abundant from the end of vegetative phase; “adults + nymphs" occurred from the beginning of reproductive phase; there were no rice stem bugs in more than 66% of the area, as they were most concentrated near the edge of the crop. The information presented here provides further knowledge about T. limbativentris spatiotemporal dynamics that can be applied to improve IPM strategies, such as developing sampling plans and localized control measures at the edge of rice fields.