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Sleep quality and falls in middle-aged and older adults: ELSI-Brazil study
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Santos, André Pereira dos

; Cordeiro, Jéssica Fernanda Correa

; Abdalla, Pedro Pugliesi

; Bohn, Lucimere

; Sebastião, Emerson

; Silva, Leonardo Santos Lopes da

; Tasinafo Júnior, Márcio Fernando

; Venturini, Ana Cláudia Rossini

; Andaki, Alynne Christian Ribeiro

; Mendes, Edmar Lacerda

; Marcos-Pardo, Pablo Jorge

; Mota, Jorge

; Machado, Dalmo Roberto Lopes

Revista da Escola de Enfermagem da USP

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2024, Volume 58 elocation e20240027

Resumo: Es Pt En | Texto: Es Pt En | PDF: Es | PDF: Pt | PDF: En

RESUMEN Objetivo: Verificar la asociación entre la baja calidad del sueño autorreportada (BCS) y las caídas en adultos de mediana edad y mayores cada media década de vida. Método: Se realizó un estudio transversal utilizando datos de la primera oleada (2015–2016) del Estudio Longitudinal Brasileño sobre el Envejecimiento (ELSI-Brasil), que es representativo a nivel nacional. La muestra consistió en 8,950 participantes que fueron asignados a ocho grupos de edad: 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, 80–84 y ≥ 85 años. Los cuestionarios utilizados incluyeron calidad del sueño autorreportada y el Cuestionario Internacional de Actividad Física versión corta. Se realizó una prueba exacta de Fisher seguida por un análisis de regresión logística binaria para identificar la razón de probabilidades de la calidad del sueño para la ocurrencia de caídas, controlando las variables de confusión. Resultados: Participaron en este estudio individuos con edades entre 50 y 105 años (63,6 ± 10,2 años), siendo el 57,0% mujeres y el 43,0% hombres. En general, el 21,5% de los participantes experimentaron al menos una caída. La frecuencia relativa de participantes clasificados como con alta calidad de sueño o baja calidad de sueño (BCS) se mantuvo constante a lo largo de cada media década de vida. La BCS mostró un OR (p < 0,05) notable para las caídas en grupos de edad hasta los 84 años, incluso después de ajustar por variables de confusión. Conclusión: La BCS está significativamente asociada con una mayor ocurrencia de caídas en adultos mayores de 50 años, pero no para ≥ 85 años, independientemente del sexo y del nivel de actividad física.

RESUMO Objetivo: Verificar a associação entre baixa qualidade do sono autorrelatada (BQS) e quedas em adultos de meia-idade e idosos a cada meia década de vida. Método: Um estudo transversal foi conduzido utilizando dados da primeira onda (2015–2016) do Estudo Longitudinal Brasileiro do Envelhecimento (ELSI-Brasil), que é nacionalmente representativo. A população consistiu em 8.950 participantes que foram alocados em oito grupos etários: 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, 80–84 e ≥ 85 anos. Os questionários utilizados incluíram qualidade do sono autorrelatada e o Questionário Internacional de Atividade Física versão curta. O teste exato de Fisher seguido pela análise de regressão logística binária foi conduzida para identificar a razão de chances da BQS para ocorrência de queda, controlando por variáveis de confusão. Resultados: Pessoas com idades entre 50 e 105 anos (63,6 ± 10,2 anos), sendo 57,0% do sexo feminino e 43,0% do sexo masculino, participaram deste estudo. No geral, 21,5% dos participantes experimentaram pelo menos uma queda. A frequência relativa de participantes classificados como tendo BQS ou alta permaneceu constante em cada meia década de vida. A BQS exibiu uma OR (p < 0,05) notável para quedas em grupos etários até 84 anos, mesmo após o ajuste para variáveis de confusão. Conclusão: A BQS está significativamente associada a uma maior ocorrência de queda em adultos com mais de 50 anos, mas não para ≥ 85 anos, independentemente do sexo e do nível de atividade física.

ABSTRACT Objective: To verify the association between low self-reported sleep quality (LSQ) and fall in middle-aged and older adults every half-decade of life. Method: A cross-sectional study was conducted using data from the first wave (2015–2016) of the Brazilian Longitudinal Study of Aging (ELSI-Brazil), which is nationally representative. The sample consisted of 8,950 participants who were allocated into eight age groups: 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, 80–84, and ≥ 85 years. The questionnaires used included self-reported sleep quality and the International Physical Activity Questionnaire short version. Fisher’s exact test followed by binary logistic regression analysis was performed to identify the odds ratio of sleep quality for fall occurrence, controlled for confounding variables. Results: Individuals aged 50–105 years (63.6 ± 10.2 years), 57.0% females and 43.0% males, participated in this study. Overall, 21.5% of participants experienced at least one fall. The relative frequency of participants classified as having high or LSQ remained constant across each half-decade of life. The LSQ exhibited a statistically significant OR (p < 0.05) for falls across age groups up to 84, even after accounting for confounding variables. Conclusion: LSQ is significantly associated with an increased occurrence of fall in adults aged >50 years, but not for ≥ 85 years regardless of sex and physical activity level.

https://doi.org/10.1590/1980-220x-reeusp-2024-0027en

Sleep quality and falls in middle-aged and older adults: ELSI-Brazil study
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Santos, André Pereira dos

; Cordeiro, Jéssica Fernanda Correa

; Abdalla, Pedro Pugliesi

; Bohn, Lucimere

; Sebastião, Emerson

; Silva, Leonardo Santos Lopes da

; Tasinafo Júnior, Márcio Fernando

; Venturini, Ana Cláudia Rossini

; Andaki, Alynne Christian Ribeiro

; Mendes, Edmar Lacerda

; Marcos-Pardo, Pablo Jorge

; Mota, Jorge

; Machado, Dalmo Roberto Lopes

Revista da Escola de Enfermagem da USP

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2024, Volume 58 elocation e20240027

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

https://doi.org/10.1590/1980-220x-reeusp-2024-0027en

Histological evaluation of the liver of mice with sarcoma-180 treated with salazinic acid sarcoma180 sarcoma 180 sarcoma-18 sarcoma18 18 sarcoma-1 sarcoma1 1 sarcoma-
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LIRA, MARIA APARECIDA DA C. DE

; SILVA, MARLLYN M. DA

; SILVA, WANESSA K.M.

; FALCÃO, EMERSON P.S.

; AGUIAR JÚNIOR, FRANCISCO C.A. DE

; MELO, SEBASTIÃO J. DE

Anais da Academia Brasileira de Ciências

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2023, Volume 95 Nº 2 elocation e20200455

Resumo: En | Texto: En | PDF: En

Abstract Many of the drugs used to fight cancer cells induce various damage causing hepatotoxic effects which are characterized by tissue changes. The aim of the study is to know the possible effects of salazinic acid on livers of mice exposed to Sacoma-180. The tumor was grown in the animals in ascitic form and inoculated subcutaneously in the axillary region of the mouse developing the solid tumor. Treatment with salazinic acid (25 and 50 mg/kg) and 5-Fluorouracil (20 mg/kg) started 24-hours after inoculation and was performed for 7 days. To verify these effects, the qualitative method of histological criteria investigated in liver tissue was used. It was observed that all treated groups showed an increase of pyknotic nuclei in relation to the negative control. There was an increase in steatosis in all groups compared to the negative control but there was a decrease in the groups treated with salazinic acid in the 5-Fluorouracil. There was no necrosis in the salazinic acid treated groups. However, this effect was seen in 20% of the positive control group. Therefore, it can be concluded that salazinic acid did not show hepatoprotective action on mice but demonstrated a decrease in steatosis and absence of tissue necrosis. changes Sacoma180. Sacoma180 Sacoma 180. 180 Sacoma-180 25 (2 5 mg/kg mgkg mg kg 5Fluorouracil Fluorouracil 20 24hours hours 24 days 5Fluorouracil. Fluorouracil. However group Therefore Sacoma18 18 Sacoma-18 2 ( Sacoma1 1 Sacoma-1 Sacoma-

https://doi.org/10.1590/0001-3765202320200455

4-amino-2-phenyl-6-(p-fluorophenyl)-5-carbonitrile-pyrimidine-bis-substituted-loaded liposomes as promising system for cancer treatment
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OLIVEIRA, JANICE V.

; ALMEIDA, GLEYBSON C.

; NOGUEIRA, MARIANE C.B.L.

; AGUIAR JÚNIOR, FRANCISCO C.A.

; MELO, AUDENES O.

; SILVA, THIAGO D.S.

; SANTOS, NOEMIA P.S.

; MAGALHÃES, NEREIDE S.S.

; MELO, SEBASTIÃO J.

; FALCÃO, EMERSON P.S.

Anais da Academia Brasileira de Ciências

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2023, Volume 95 Supl. 1 elocation e20211078

Resumo: En | Texto: En | PDF: En

Abstract The aim of the present study was to perform in vitro and in vivo assessments of the antineoplastic action of 4-amino-pyrimidine encapsulated in liposomes. Liposomes were prepared and characterized for particle size and drug encapsulation and submitted to long-term stability tests. Cytotoxicity assays were performed in HeLa cells. Antineoplastic activity was investigated using the experimental sarcoma 180 tumor in Swiss albino mice. Encapsulation efficiency was 82.93 ± 0.04% and no significant changes were found with respect to particle size or pH after centrifugation and mechanical agitation tests. The in vitro results at concentration of 20 μg/mL indicated a considerable reduction in cell viability after treatment with encapsulated pyrimidine (75.91%). The in vivo assays using the compounds in encapsulated and free forms and 5-fluorouracil achieved tumor inhibition rates of 66.47 ± 26.8%, 50.46 ± 16.24% and 14.47 ± 9.22%, respectively. Mitotic counts demonstrated a greater reduction in the number of mitoses in animals treated with liposomal pyrimidine (32.15%) compared to those treated with the pyrimidine free (87.69%) and 5-fluorouracil (71.39%). This study demonstrated that the development of liposome formulations containing 4-amino-pyrimidine is a promising alternative for overcoming limitations related to the toxicity of current cancer treatment, ensuring greater therapeutic efficacy.

https://doi.org/10.1590/0001-3765202320211078

VALORAÇÃO DA ATIVIDADE FÍSICA: DISCUSSÃO SOBRE UMA IDEIA IDENTIFICADA MAS NÃO CONTEXTUALIZADA NA LITERATURA
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Silva, Ana Flávia Andalécio Couto da

; Papini, Camila Bosquiero

; Sebastião, Emerson

; Brunheroti, Karina

; Andaki, Alynne Christian Ribeiro

; Kokubun, Eduardo

Movimento

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2023, Volume 29 elocation e29057

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract The valuation of physical activity has not yet been established as a concept or definition in the literature. Thus, the objective of the present study was to understand the concept and foster a preliminary discussion about the valuation of physical activity, through a systematic literature review followed by an integrative review with different search strategies. Considering the systematic review inclusion criteria, studies addressing the concept or definition of physical activity valuation were not identified. However, from the selection and reading of the articles in the integrative review, we sought to understand in which contexts the studies about physical activity valuation methods were developed. It is suggested that the valuation of physical activity is associated with the importance given by the individuals to physical activity, i.e. a broad concept related to value judgment regarding physical activity; the valuation of physical activity can be related to the hedonic pricing, the contingent valuation, and the avoided costs.

Resumen La valoración de la actividad física es un enfoque no evidenciado como concepto o definición. Así, el objetivo del presente estudio fue comprender la conceptualización y promover una discusión preliminar sobre la valoración de la actividad física, a través de una revisión sistemática de la literatura seguida de una revisión integradora, utilizando diferentes estrategias de búsqueda. Con base en los criterios de inclusión de la revisión sistemática, no se identificaron estudios que buscaran definir y/o conceptualizar la valoración de la actividad física. Sin embargo, a partir de la selección y lectura de artículos en la revisión integradora, buscamos comprender en qué contextos se desarrollaron los estudios y qué métodos de valoración se referían a la actividad física. Se sugiere que la valoración de la actividad atañe a la importancia que el individuo le da a la actividad física, o sea, un juicio de valor determinado a la actividad física que puede relacionarse con el costo hedónico, la valoración contingente y el costo evitado.

Resumo A valoração da atividade física é uma abordagem não evidenciada como conceito ou definição. Assim, o objetivo do presente estudo foi compreender a conceituação e fomentar uma discussão preliminar acerca da valoração da atividade física, por meio de uma revisão sistemática de literatura seguida de uma revisão integrativa utilizando diferentes estratégias de busca. A partir dos critérios de inclusão da revisão sistemática não foram identificados estudos que procuraram definir e/ou conceituar a valoração da atividade física. Porém, a partir da seleção e leitura dos artigos na revisão integrativa, buscou-se compreender em quais contextos os estudos foram desenvolvidos e quais os métodos de valoração se referiam à atividade física. Sugere-se que a valoração da atividade diz respeito à importância que o indivíduo direciona a atividade física, ou seja, um juízo de valor determinado à atividade física que pode se relacionar ao custo hedônico, valoração contingente e ao custo evitado.

https://doi.org/10.22456/1982-8918.127334

The importance of promoting physical activity and exercise training as adjuvant therapy for people with multiple sclerosis
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Sebastião, Emerson

; Wood, Tyler

; Motl, Robert Wayne

; Santinelli, Felipe Balistieri

; Barbieri, Fabio Augusto

Motriz: Revista de Educação Física

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2022, Volume 28 elocation e10220016021

Resumo: En | Texto: En | PDF: En

Abstract Aim: This review aimed to provide evidence and highlight the importance of including physical activity (PA) and/or exercise training (ET) as part of the comprehensive multiple sclerosis (MS) care. Methods: Using the current literature on the subject, we provide a brief overview of MS incorporating its definition, common symptoms, prevalence, and potential disease consequences. We further succinctly describe MS as the first line of treatment, as well as the role of PA and ET in the disease. We end the commentary highlighting important recommendations from an international initiative to improve MS-related physical activity research that we believe will help not only improve the area of study but also best practices within this population. Results: There is compelling evidence for the beneficial effects of PA and/or ET on MS-related symptoms and consequently health and quality of life. There is preliminary evidence suggesting the potential for a disease-modifying effect. Conclusion: Fomenting this discussion is timely due to the increased prevalence of MS in different regions of the globe, and people with MS report low levels of PA participation and high amounts of sedentary time. The consequences of inactivity in this population can be drastic. The current body of evidence supports the notion that PA and ET are safe health behaviors that should be adopted as an adjuvant treatment option within the comprehensive and complex MS care due to its benefits on a variety of disease-related symptoms and its potential for improving health and quality of life in this population.

https://doi.org/10.1590/s1980-657420220016021

Barriers to physical activity among cancer pediatric cancer patients and survivors: a scoping review
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Guimarães, Jean Augusto Coelho

; Guerra, Paulo Henrique

; Ueno, Deisy Terumi

; Spósito, Letícia Aparecida Calderão

; Sebastião, Emerson

; Nakamura, Priscila Missaki

Motriz: Revista de Educação Física

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2022, Volume 28 elocation e10220005621

Resumo: En | Texto: En | PDF: En

Abstract Aim: The present scoping review aims to provide an overview of barriers to PA reported by pediatric cancer patients undergoing treatment as well as after treatment. This study further aims to describe and discuss the instruments used for assessing barriers in this population. Methods: Article search was performed in common medical databases and yielded five original research articles. Results: The included articles reported barriers to PA that can be grouped into the following categories: individuals, physical, environmental, and treatment. Among the instruments used to assess barriers to PA, it was observed that questionnaires and interviews are commonly adopted. This review underscores a paucity of studies in this area. Conclusion: A comprehensive understanding of barriers to PA in the pediatric cancer population is paramount for the development of tailored strategies and interventions aiming to promote PA in this under-researched group. In addition, future studies must adopt a mixed-methods approach, longitudinal design with specific instruments in the pediatric cancer population.

https://doi.org/10.1590/s1980-657420220005621

Treatment of knee osteoarthritis with a new formulation of a fixed-dose combination of glucosamine sulfate and bovine chondroitin: a multicenter, randomized, single-blind, non-inferiority clinical trial
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Lomonte, Andrea Barranjard Vannucci

; Gimenez, Emerson Silva, Antônio Carlos da Radominski, Sebastião Cezar Scheinberg, Morton Aaron Ximenes, Antônio Carlos Zerbini, Cristiano Augusto de Freitas

Advances in Rheumatology

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2021, Volume 61 elocation 7

Resumo: En | Texto: En | PDF: En

Abstract Objectives: To compare the efficacy and safety of a new formulation of a fixed dose combination of glucosamine sulfate (GS; 1500 mg) and bovine chondroitin sulfate (CS; 1200 mg) versus the reference product (RP) in patients with knee osteoarthritis (OA). Methods: In this multicenter, randomized, single-blind trial, 627 patients with knee osteoarthritis (OA)—Kellgren-Lawrence grades 2 or 3 and mean score ≥ 40 mm in the WOMAC pain subscale—were randomized to receive GS/ CS or the RP for 24 weeks. The primary efficacy endpoint was the absolute change in WOMAC pain subscale score. The secondary endpoints included the following: WOMAC total and subscale scores, overall assessment of the disease by the patient and the investigator, SF-12 score, OMERACT-OARSI response rate to the treatment, and rescue medication use. Results: Mean reductions of WOMAC pain score were – 35.1 (sd = 23.2) mm in the GS/CS group and – 36.5 (sd = 24.9) mm in the RP group. The difference between the adjusted means of both treatments confirmed the noninferiority of GS/CS versus the RP. Improvement was observed in pain, stiffness, physical function and total WOMAC score, as well as in overall OA assessment by the patient and the investigator for both groups. No improvement was observed in SF-12. The rate of OMERACT-OARSI responders was 89.4% in GS/CS group and 87.9% in the RP group. Headache and changes in glucose tolerance were the most frequent treatment-related adverse events. Conclusions: The new formulation of a fixed-dose combination of glucosamine sulfate and bovine chondroitin sulfate was non-inferior to the RP in symptomatic treatment of knee OA, with a high responder rate and good tolerability profile. Trial registration: ClinicalTrials.gov; Registration number NCT02830919; Date of registration: July 13, 2016; First randomization date: December 05, 2016).

https://doi.org/10.1186/s42358-021-00165-9 590 downloads

Outdoor Fitness Zone: utilization pattern, and environmental and individual characteristics associated with the volume of utilization
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Silva, Debora Bernardo da

; Sebastião, Emerson

; Sousa, Thiago Ferreira de

; Tribess, Sheilla

; Papini, Camila Bosquiero

Motriz: Revista de Educação Física

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2021, Volume 27 elocation e10210022920

Resumo: En | Texto: En | PDF: En

Abstract Aim: To examine the association between environmental and individual characteristics and utilization pattern of Outdoor Fitness Zones (OFZ) with the volume of utilization of these public spaces in Uberaba, Brazil. Methods: Cross-sectional descriptive study. Data collection was conducted using “in loco” interviews (three different days and times) and direct observation of nine OFZ. Poisson regression analysis was used to estimate prevalence ratios using the volume of utilization higher than 90 min per week as the dependent variable and a collection of socio-demographic, environmental, utilization pattern, and OFZ characteristics as independent variables. Results: Adjusted analysis revealed that volume of utilization higher than 90 min per week of OFZ was associated with a higher prevalence ratio among users utilizing such spaces to meet friends sometimes (PR = 2.43; 1.21-4.90) and always (PR = 3.43; 1.61-7.34) compared to not meeting friends. A lower prevalence ratio was found in users who attend the OFZ only during the week or only weekend days (PR = 0.52; 0.37-0.73) compared to a user who attends both (week and weekends days). OFZ not providing a space for walking or jogging (PR = 0.48; 0.23-0.99) were also associated with a lower prevalence ratio of utilization higher than 90 min per week. Conclusions: The findings demonstrated that most individual and environmental characteristics and utilization patterns of the OFZ in the city of Uberaba, MG, Brazil, were not associated with the volume of utilization. Users who meet friends and attend both week and weekend days OFZ that features walking or running trails were associated with a higher volume of utilization.

https://doi.org/10.1590/s1980-657420210022920 43 downloads

10.

Pyrimidine Derivatives: QSAR Studies of Larvicidal Activity against Aedes aegypti
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Monte, Zenaide S.

; Navarro, Daniela M. A. F.

; Aguiar, Júlio C. R. O. F.

; Nascimento, Jessica S. Scotti, Marcus T. Scotti, Luciana Barros, Renata P. C. Santos, Aline C. S. Pereira, Valéria R. A. Falcão, Emerson P. S. Melo, Sebastião J.

Journal of the Brazilian Chemical Society

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Jul 2020, Volume 31 Nº 7 Páginas 1531 - 1540

Resumo: En | Texto: En | PDF: En

The present study investigated the activity of pyrimidine derivatives against Aedes aegypti. Two compounds, 3c and 3d showed excellent larvicide activity. Additionally, quantitative structure-activity relationship (QSAR) models were built using multiple-linear regression and partial least squares with descriptors generated from Dragon and VolSurf+ software, respectively. The best model is obtained with multiple linear regression (MLR), leading to a robust model. Moreover, the QSAR model is validated by means of some internal validation techniques in order to check its reliability, quality and robustness for predicting the larvicidal activity against A. aegypti. The models confirmed that the three-dimensional structure of molecules, steric properties, hydrophobic polar surface area, log partition (logP) and a simple pattern of substituent groups as methyl, methoxy, and succinimide in the pyrimidine derivatives are responsible for the larvicidal activity of the pyrimidine derivatives. Even more, the activity decreases by an electron-withdrawing group in R1 and increases when it is replaced by an aromatic ring activator group. These findings will aid in further studies of new pyrimidine derivatives active against Aedes aegypti.

https://doi.org/10.21577/0103-5053.20200039 283 downloads

11.

PREVALENCE AND SOCIODEMOGRAPHIC FACTORS ASSOCIATED WITH SEDENTARY BEHAVIOR IN ADOLESCENTS FROM RIO CLARO-SP, BRAZIL
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Christofoletti, Ana Elisa Messetti

; Benites, Larissa Cerignoni

; Sebastião, Emerson

; Ueno, Deisy Terumi

; Nakamura, Priscila Missaki

Journal of Physical Education

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2020, Volume 31 elocation e3159

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo do estudo foi analisar a prevalência, os fatores sociodemográficos e o comportamento sedentário (CS) associados as situações do CS (1) obrigações; 2) computador/tablet e videogame; 3) smartphone; 4) televisão; 5) CS total) de adolescentes de Rio Claro-SP. Participaram do estudo 482 adolescentes (14,4±2,1 anos) de 3 escolas públicas e 2 particulares, avaliados por um questionário de identificação, anamnese clínica e nível socioeconômico; Questionário de Comportamento Sedentário, com questões adicionais relacionadas ao CS e o uso de smartphones e videogames; Questionário de Atividade Física Habitual para Adolescentes; e mensuração do peso e estatura para o cálculo de Índice de Massa Corporal (IMC) (kg/m²). Realizou-se análise descritiva, teste t de Student para comparar as situações de CS e nível de atividade física entre meninos e meninas e regressão logística para verificar a associação das situações com o CS total (p<0,05). Identificou-se que 47,5% dos adolescentes permanecem mais de 14 horas/dia em CS (média de 13,7±3,4 horas/dia). As situações associados ao CS total foram: smartphone (RO=6,23; p<0,001); computador/tablet e videogame (RO=2,5; p=0,012); obrigações (RO=2,43; p=0,009) e televisão (RO=2,35; p=0,009). Relatou-se alta prevalência de CS, porém não houve nenhum fator sociodemográfico associado com esse comportamento. Adicionalmente, o uso do smartphone apresentou maior associação com o alto tempo de CS total.

ABSTRACT The objective of this study was to analyze the prevalence of and sociodemographic factors associated with sedentary behavior (SB) situations among adolescents from Rio Claro, São Paulo, Brazil, namely: (1) obligations; 2) computer/tablet and video game; 3) smartphone; 4) television; 5) total SB. It included 482 teenagers (14.4 ± 2.1 years old) from 3 public and 2 private schools. They were assessed through an identification, clinical history and socioeconomic level questionnaire; Sedentary Behavior Questionnaire, with additional questions related to SB and use of smartphones and video games; Habitual Physical Activity Questionnaire for Adolescents; and weight and height measurement for Body Mass Index (BMI) calculation (kg/m²). Descriptive analysis was performed, Student’s t test was run to compare SB situations and level of physical activity between boys and girls, and logistic regression was carried out to verify the association of the situations with total SB (p <0.05). Results revealed that 47.5% of the adolescents spend more than 14 hours/day on SB (mean of 13.7 ± 3.4 hours/day). The situations associated with total SB were: smartphone (OR=6.23; p<0.001); computer/tablet and video game (OR=2.5; p=0.012); obligations (OR=2.43; p=0.009) and TV (OR=2.35; p=0.009). High SB prevalence was found, but there was no sociodemographic factor associated with this behavior. Additionally, smartphone use presented a greater association with high amount of time for total SB.

https://doi.org/10.4025/jphyseduc.v31i1.3159 268 downloads

12.

Effectiveness of exercise and health education interventions in Brazilian primary health care
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Polo, Maria Clara Elias

; Tavares, Giselle Helena

; Kanitz, Ana Carolina

; Sebastião, Emerson

; Papini, Camila Bosquiero

; Silva, Danilo Rodrigues Pereira da

Motriz: Revista de Educação Física

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2020, Volume 26 Nº 3 elocation e10200004

Resumo: En | Texto: En | PDF: En

Abstract AIM This study examined the effectiveness of two different behavioral change interventions to improve Physical Activity (PA) and to reduce Sedentary Behavior (SB) in a primary health care setting. METHODS This quasi-experimental study recruited and enrolled 31 users of a primary health care unit of the Brazilian Unified Health System aged 18 or more. Participants were allocated into two groups: Physical Exercise Group combined with Health Education (EHE) and Health Education Group (HE). The EHE group participated in 60 minutes of exercise, twice a week, and 20 minutes of counseling. The HE group participated in 40 minutes of counseling, once a week. Both programs were conducted for over 18 weeks. PA levels were self-reported (IPAQ) and PA and SB were objectively (accelerometer) assessed before and after the intervention period. Data were analyzed using intention-to-treat analysis with generalized estimating equations adopting p<0.05 for significance. Also, the individual PA and SB deltas were computed. Improvements in PA and SB were observed for both interventions (p<0.05). RESULTS Both groups increased the minutes of weekly leisure PA (p=0.006), time spent in light (p=0.003), and moderated-to-vigorous (p=0.042) PA and decreased the amount of SB, with a significant decrease in the HE group (p=0.010). Delta analyses further demonstrated the effectiveness of the interventions to increase PA in other domains (i.e., transportation, household) and maintenance of occupational PA. CONCLUSION Behavioral change interventions in the primary health care context involving exercise and counseling seem to be effective in improving PA and SB in adults.

https://doi.org/10.1590/s1980-6574202000030004 654 downloads

13.

Effects of Acute Physical Exercise and Television Viewing on Mood in Older Active Women
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Christofoletti, Ana Elisa Messetti

; Sebastião, Emerson

; Ueno, Deisy Terumi

; Bonolo, Angélica

; Deutsch, Silvia

; Nakamura, Priscila Missaki

Motriz: Revista de Educação Física

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2019, Volume 25 Nº 1 elocation e101973

Resumo: En | Texto: En | PDF: En

Abstract Aim: Due to the increased prevalence of mood disorders and the detrimental effects of sedentary behavior on health, a better understanding of the association between physical exercise (PE), TV viewing and mood in older adults is paramount. This is based on the fact that mood has been recognized as an important predictor of longevity, well-being, and quality of life. This study examined the effects of an acute bout of physical exercise (PE) and television viewing (TV) on positive and negative mood states of older active women. Methods: Fifty-four women aged 60 years and older were asked to complete the Abbreviated and Illustrated Mood States Inventory (LEA-RI) before and immediatly after two distinct activities: 1) single bout of PE; and 2) a single bout of TV. Participants further completed questionnaires to provide information on demographics, physical activity and sedentary behavior for sample characterization. Differences between conditions (PE and TV) on positive and negative mood state were analyzed using repeated measures ANOVA followed by paired sample t-test adopting a significance level of P<.05. Results: Positive mood states significantly increased for the PE (P=0.001) but not for the TV condition (P=0.388). Negative mood states significantly increased for the PE condition (P=0.003) but significantly reduced for the TV condition (P=0.011). Conclusions: The findings suggest that a single bout of PE may be more beneficial to improve positive mood compared to a single bout of TV. However, the TV may be able to reduce negative mood in older active women.

https://doi.org/10.1590/s1980-6574201900010016 834 downloads

14.

Sobre a melhoria da produção e da avaliação de periódicos científicos no Brasil
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Ponce, Branca Jurema Almeida, Maria Elizabeth Biaconcini de Freitas, Silvana Alves Silva, Cícero Barbosa da Anjos, Daniela Pietri, Emerson de Prieto, Rosângela Gavioli Dias, Érika S. de Almeida C. Camargo, Evani Branco, Jordanna Castelo Souza, José dos Santos Bizelli, José Luís Siman, Lana Mara de Castro Muzzeti, Luci Regina Reis, Magali dos Martins, Edna Rosito, Margaréte May Benkenbrock Bissoto, Maria Luisa Castro, Monica Rabelo de Gimenes, Nelson Gualtieri, Regina Silva, Regis Ribeiro, Ricardo Lemes, Sebastião de Souza

Ensaio: Avaliação e Políticas Públicas em Educação

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Dez 2017, Volume 25 Nº 97 Páginas 1032 - 1044

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo O documento que apresentamos é fruto da reflexão de Editores de Periódico Científicos ligados ao FEPAE Sudeste – Fórum de Editores de Periódicos da Área de Educação Sudeste – e expressa preocupações concretas sobre as condições materiais para a realização de seu trabalho, assim como, sobre os critérios de avaliação que vêm sendo utilizados para qualificar suas revistas. Orçamentos mais enxutos, o desmonte de estruturas universitárias que sustentavam muitas revistas acadêmicas e indexadores que cada vez mais complicam os procedimentos operacionais envolvidos na produção editorial, fragilizam as revistas nacionais. Falta de visibilidade sobre os processos de avaliação, ausência de diálogo sobre resultados e questões ligadas à periodicidade do QUALIS trazem uma insegurança para os autores que têm nos periódicos o veículo de divulgação de suas práticas e teorias. Queremos, assim, adensar a discussão com a comunidade científica e a Agência Reguladora Governamental, sobre os destinos que estarão reservados aos Periódicos Científicos brasileiros.

Abstract The document we presented is the result of the reflection of Editors of Scientific Journals connected to FEPAE Southeast and expresses concrete concerns about the material conditions for the realization of its work and about the evaluation criteria that have been used to qualify its journals. Cheaper budgets, dismantling of university structures that supported many academic journals and indicators which everytime complicate even more the operational procedures involved in editorial production, undermine the national journals. Lack of visibility about the evaluation procedures, absence of dialogue about results and questions connected to the Qualis frequency bring uncertainty for the authors who have in the journals a vehicle for sharing its practices and theories. This way we want to deepen the discussion with the scientific community and the Regulatory Governmental Agency - CAPES - about the destinations reserved to Brazilian Scientific Journals.

Resumen El documento que presentamos es fruto de la reflexión de Editores de Revistas Científicas ligadas al FEPAE Sudoeste – Foro de Editores de Revistas del Área de Educación Sudoeste – y expresa preocupaciones concretas sobre las condiciones materiales para la realización de su trabajo, así como sobre los criterios de evaluación que vienen siendo utilizados para calificar sus revistas. Presupuestos más restrictos, el desmonte de estructuras universitarias que sustentaban muchas revistas académicas e indexadores que cada vez complican más los procedimientos operacionales involucrados en la producción editorial, fragilizan a las revistas nacionales. Falta de visibilidad sobre los procesos de evaluación, ausencia de diálogo sobre resultados y cuestiones ligadas a la periodicidad del QUALIS representan incertidumbre para los autores que ven a las revistas como un vehículo de divulgación de sus prácticas y teorías. Queremos, así, enriquecer la discusión con la comunidad científica y la Agencia Reguladora Gubernamental, sobre los destinos que estarán reservados a las Revistas Científicas brasileras.

https://doi.org/10.1590/s0104-40362017002501032 1749 downloads

15.

Synthesis and evaluation of arylamidine derivatives for new antimicrobial and cytotoxic activities
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MONTE, ZENAIDE S. SILVA, AMANDA M. LIMA, GLÁUCIA M.S. SILVA, TERESINHA G. DA MARQUES, KARLA M.R. RODRIGUES, MARIA D. FALCÃO, EMERSON P.S. MELO, SEBASTIÃO J.

Anais da Academia Brasileira de Ciências

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Jun 2017, Volume 89 Nº 2 Páginas 1051 - 1059

Resumo: En | Texto: En | PDF: En

ABSTRACT A series of arylamidines 3a-j was designed, synthesized and investigated for antimicrobial activity. Structures of the compounds were confirmed by IR, 1H-NMR and 13C-NMR and a 2D spectroscopic study was performed. A preliminary screening of the antimicrobial tests clearly showed that three out of ten arylamidines, viz, 3f, 3g and 3i, were effective against all the gram-negative bacteria: Klebsiella pneumoniae, Pseudomonas aeruginosa and Salmonella enteric; and against the yeast, candida albicans. Further, the Minimum Inhibitory Concentrations (MIC) against the bacteria and yeast were determined. All compounds 3a-d, 3f, 3g, 3i and 3j were also investigated for their low cytotoxic effects on tested cell lines. Compounds 3d and 3f were the most effective derivatives against HL-60 and HEp-2 cells, respectively, with IC50 value (2µg/mL), and low normal cells toxicity.

https://doi.org/10.1590/0001-3765201720160801 1472 downloads

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