ABSTRACT Purpose: Although Brazil has a high prevalence of retinoblastoma, there is a lack of epidemiological data on the disease. Thus, in this study, we aimed to evaluate the epidemiological profile of patients diagnosed with retinoblastoma in the ophthalmology department of a pediatric tertiary referral hospital in Ceara, Brazil. Methods: A descriptive and cross-sectional study was conducted by retrospectively analyzing the clinical and socioeconomic data from the medical records of pediatric patients followed-up at the hospital between 2007 and 2021. Retinoblastoma was diagnosed on the basis of a fundoscopic or histopathologic examination. Results: The data of 105 patients were included in the study, and the mean patient age at the time of diagnosis was 1.7 years. Most of the patients were women (50.5%) and hailed from rural areas (57.4%), which was associated with a higher tumor stage. Of the 150 patients, 57.1% initially presented with leukocoria. Ocular hyperemia was associated with more advanced stages of retinoblastoma (p=0.004). Bilateral involvement was observed in 25.7% of the patients and at a significantly younger age (p=0.009). The presence of retinal detachment, vascularized lesions, and vitreous seeds significantly increased the likelihood of requiring enucleation. Discussion: This study presents an epidemiological description of retinoblastoma in Brazil, which highlights the significance of early detection. Delayed diagnosis is associated with a poorer visual prognosis and higher mortality rate, particularly in patients with unilateral disease. Risk factors for a more severe disease were retinal detachment, vascularized lesions, and vitreous seeds. The correlation between histopathological features and clinical outcomes was limited. Conclusion: Further studies are required to assess the influence of ocular hyperemia, fundoscopic assessment, and histopathologic findings on the prognosis of retinoblastoma. Moreover, it is critical to devise interventions to reduce the time-to-diagnosis in rural areas. Purpose Thus Ceara Methods crosssectional cross sectional followedup followed up 200 2021 examination Results 10 17 1 7 1. years 50.5% 505 50 5 (50.5% 57.4%, 574 57.4% , 57 4 (57.4%) stage 15 571 57.1 leukocoria p=0.004. p0004 p p=0.004 . 0 004 (p=0.004) 257 25 25.7 p=0.009. p0009 p=0.009 009 (p=0.009) detachment lesions enucleation Discussion detection rate limited Conclusion assessment Moreover timetodiagnosis 20 202 50.5 (50.5 57.4 (57.4% 57. p000 p=0.00 00 (p=0.004 2 25. (p=0.009 50. (50. (57.4 p00 p=0.0 (p=0.00 (50 (57. p0 p=0. (p=0.0 (5 (57 p=0 (p=0. ( p= (p=0 (p= (p

ABSTRACT: The selection of wheat genotypes according to their drought tolerance is essential to off-season cultivation. The objective of this work was to characterize wheat genotypes through yield and components, morphological characteristics under water stress, and irrigated water use efficiency in the Cerrado region in Brazil. Genotypes were planted during the winters of 2016 and 2017 since there is no precipitation during this season and water levels can be measured. They were then submitted to four water regimes: WR1, WR2, WR3, and WR4, representing 100 %, 83 %, 50 %, and 30 % of evapotranspiration replacement. The following variables were evaluated: peduncle length (PL), number of ears m−2 (NE m−2), hectoliter weight (HW), thousand grain weight (TGW), drought resistance index (DRI), irrigated water use efficiency (IWUE) and yield. Most variables showed correlation with yield and can be a useful tool for breeding programs. PL and HW were best correlated with yield. BRS 264 (irrigated biotype) was productive in treatments receiving the greatest number of irrigation treatments. Given that WR1 registered the highest water level, it was not expected that the rainfed biotype (BR18) would show a higher yield than an irrigated biotype (BRS254). BRS404 (rainfed biotype) was the most productive under moderate stress treatment (WR3). Aliança (rainfed biotype) showed a higher yield under severe stress. Rainfed biotypes presented a higher DRI than the irrigated ones. These genotypes can be used as a reference in breeding programs under each water regime in which their performance was outstanding. None of the variables studied contributed to the selection of the most efficient wheat genotypes in the IWUE.

RESUMO A avaliação da implantação de políticas e programas para melhorias na saúde infantil é essencial. Este estudo pretende avaliar a eficácia do Programa Rede Mãe Paranaense, criando um índice avaliativo para os objetivos do programa referentes ao seguimento da criança, a fim de estipular o grau em que foram concretizados. Foram entrevistadas 139 mulheres usuárias do programa. A pesquisa utilizou dados do instrumento elaborado e analisou a Caderneta de Saúde da Criança. A análise de dados foi realizada a partir da comparação entre frequências relativas obtidas no estudo e as propostas do programa, calculando-se a razão entre essas frequências para se obter o índice avaliativo, ou seja, para descobrir quanto foi alcançado da meta estipulada. As variáveis foram categorizadas em domínios definidos no programa, gerando um índice avaliativo para cada um deles. No domínio ‘Satisfação Materna’, a meta foi 68% atingida; no ‘Acompanhamento na Puericultura’, foram atingidos 67%; na ‘Qualidade e Resolubilidade na Assistência’, 55%; e na ‘Estratificação de Risco’, somente 6% da meta foram alcançados. Conclui-se que os índices avaliativos retratam baixa eficácia no seguimento da criança. O estudo evidenciou a necessidade de revisão das estratégias utilizadas no seguimento da saúde da criança para melhorar os índices assistenciais na Atenção Primária à Saúde.

ABSTRACT Assessing the implementation of policies and programs for improving child health is essential. This study aimed at assessing the effectiveness of the Rede Mãe Paranaense Program, creating an evaluative index for the objectives of the program regarding child follow-up, in order to stipulate the degree to which they were implemented. 139 women who used the program were interviewed. The research used data from the elaborated instrument and analyzed the Child Health Handbook. Data analysis was performed by comparing the relative frequencies obtained in the study and those proposed by the program, calculating the ratio between these frequencies to obtain the evaluative index, i.e., to find out how much was achieved from the stipulated goal. The variables were categorized into domains defined in the program, generating an evaluative index for each of these. In the ‘Maternal Satisfaction’ domain, the goal was 68% achieved; in ‘Follow-up in childcare’, 67% was achieved; in ‘Quality and Resolvability in Care’ 55%; and ‘Risk Stratification’, only 6% of the goal was achieved. It is concluded that the evaluative indexes portray low efficacy in following the child. The study evidenced the need to review the strategies used in the follow-up of child health to improve care indices in Primary Health Care.

RESUMO A avaliação da implantação de políticas e programas para melhorias na saúde infantil é essencial. Este estudo pretende avaliar a eficácia do Programa Rede Mãe Paranaense, criando um índice avaliativo para os objetivos do programa referentes ao seguimento da criança, a fim de estipular o grau em que foram concretizados. Foram entrevistadas 139 mulheres usuárias do programa. A pesquisa utilizou dados do instrumento elaborado e analisou a Caderneta de Saúde da Criança. A análise de dados foi realizada a partir da comparação entre frequências relativas obtidas no estudo e as propostas do programa, calculando-se a razão entre essas frequências para se obter o índice avaliativo, ou seja, para descobrir quanto foi alcançado da meta estipulada. As variáveis foram categorizadas em domínios definidos no programa, gerando um índice avaliativo para cada um deles. No domínio ‘Satisfação Materna’, a meta foi 68% atingida; no ‘Acompanhamento na Puericultura’, foram atingidos 67%; na ‘Qualidade e Resolubilidade na Assistência’, 55%; e na ‘Estratificação de Risco’, somente 6% da meta foram alcançados. Conclui-se que os índices avaliativos retratam baixa eficácia no seguimento da criança. O estudo evidenciou a necessidade de revisão das estratégias utilizadas no seguimento da saúde da criança para melhorar os índices assistenciais na Atenção Primária à Saúde.

ABSTRACT Assessing the implementation of policies and programs for improving child health is essential. This study aimed at assessing the effectiveness of the Rede Mãe Paranaense Program, creating an evaluative index for the objectives of the program regarding child follow-up, in order to stipulate the degree to which they were implemented. 139 women who used the program were interviewed. The research used data from the elaborated instrument and analyzed the Child Health Handbook. Data analysis was performed by comparing the relative frequencies obtained in the study and those proposed by the program, calculating the ratio between these frequencies to obtain the evaluative index, i.e., to find out how much was achieved from the stipulated goal. The variables were categorized into domains defined in the program, generating an evaluative index for each of these. In the ‘Maternal Satisfaction’ domain, the goal was 68% achieved; in ‘Follow-up in childcare’, 67% was achieved; in ‘Quality and Resolvability in Care’ 55%; and ‘Risk Stratification’, only 6% of the goal was achieved. It is concluded that the evaluative indexes portray low efficacy in following the child. The study evidenced the need to review the strategies used in the follow-up of child health to improve care indices in Primary Health Care.

Recent studies have shown that pollen analyses of natural substrates can produce data valuable for understanding the local pollen productivity and dispersal, deposition, and preservation potential of pollen grains. In this study, we aimed to acquire novel information about the dynamics and preservation of pollen in Caatinga environment through the palynological study of moss polsters. Samples of moss polsters in soil (MPS) and on rock (MPR) were collected from the Canudos Biological Station in the Bahia State (Brazil) and subjected to standard chemical treatments for the extraction of pollen residues. In total, 372 pollen types were recorded from the samples of which the taxonomical affinity of 140 was determined. The most represented families were Fabaceae (23 pollen types/16.42%) and Asteraceae (12 pollen types/8.57%). The MPS samples had a higher pollen concentration (21,042.04 pollen grains/cm²) than the MPR samples (7,829.35 pollen grains/cm²). On the other hand, the MPR samples had a greater diversity (68.26% of the identified pollen types). Qualitative analysis showed that the plants of shrub and subshrub habits had the greatest representation among the pollen types (35.0%). Overall, moss polsters proved to be excellent natural air pollen collectors in Caatinga environment, provided they had moist microhabitats for their development.

Objetivou-se avaliar os efeitos da inclusão de ureia de liberação lenta em substituição à ureia convencional na dieta sobre as características de carcaça de ovinos confinados. Foram utilizados 20 ovinos Santa Inês x SRD, machos não castrados, com peso corporal inicial de 21,1±1,2 kg e idade média de 120 dias, distribuídos nos tratamentos na forma de delineamento inteiramente casualizado. Os níveis de substituição utilizados como tratamentos foram 0; 20; 40; 60 e 80%, compondo dietas de aproximadamente 12% de proteína bruta, com 50% de feno de capim tifton-85 e 50% de concentrado. Não houve influência da ureia de liberação lenta sobre o peso corporal ao abate (35,17 kg) e os pesos de carcaça quente (16,75 kg) e fria (16,24 kg), entretanto, os rendimentos dessas carcaças apresentaram comportamento quadrático, revelando menores percentuais aos níveis de substituição de 48,5 e 47,63%, respectivamente. Os pesos e rendimentos dos cortes não variaram, exceto para o braço posterior, cujos valores apresentaram comportamento cúbico. As medidas objetivas da carcaça, área de olho de lombo, e as avaliações subjetivas de conformação, acabamento e marmoreio das carcaças não foram influenciadas. A espessura de gordura subcutânea decresceu de forma linear (4,25 a 2,48 mm). A inclusão de ureia de liberação lenta na dieta altera os rendimentos e reduz a gordura subcutânea, contudo, não influencia nas demais características da carcaça.

This study aimed to evaluate the effects of adding slow-release urea to replace conventional urea in the diet on carcass characteristics of feedlot sheep. We used 20 Santa Ines x SRD rams, with average body weight of 21.1±1.2 kg and average age of 120 days, distributed in a completely randomized design with 5 treatments. The replacement levels used as treatments were 0, 20, 40, 60, and 80%, composing diets of about 12% crude protein, with 50 % Tifton-85 hay and 50% concentrate. There was no influence of slow release urea on weight at slaughter (35.17 kg), and on hot (16.75 kg) and cold (16.24 kg) carcass weight, but the yield of these carcasses showed quadratic trend, revealing lower percentages at 48.5 and 47.63% replacement levels, respectively. The weights and yields of cuts did not change, except for the posterior arm, whose values showed a cubic trend. Objective measures of carcass, loin eye area, and subjective evaluations of conformation, finishing and marbling of carcasses were not affected. The subcutaneous fat thickness decreased linearly (4.25 to 2.48 mm). The inclusion of slow release urea in the diet changes the yield and reduces subcutaneous fat, however, it does not influence other carcass characteristics.

Objetivou-se neste trabalho avaliar os efeitos da inclusão de ureia em dietas contendo farelo da vagem de algaroba sobre o balanço de nitrogênio, N-ureico no plasma e parâmetros ruminais em ovinos. Foram utilizados oito animais, machos castrados, com peso médio de 33,5 kg, distribuídos em dois quadrados latinos 4 x 4. Os tratamentos constituíram da inclusão de níveis de ureia na dieta, sendo: 0; 0,5; 1,0 e 1,5% da MS total. A dieta foi fornecida como dieta total na relação volumoso:concentrado de 40:60 com base na MS total da dieta. Foi realizada a coleta total de urina e fezes e determinada a excreção de nitrogênio. Foi coletado sangue, seguido com a extração do plasma e determinação do N-ureico. Para avaliação do pH e N-amoniacal no líquido ruminal foram utilizados quatro animais fistulados no rúmen. A ingestão de N (31,68 g dia-1) e perdas vias fecal (7,94 g dia-1) e urinária (9,95 g dia-1) não sofreram alterações. As concentrações de N-amoniacal e N-ureico no plasma aumentaram de forma linear. O pH ruminal foi semelhante entre os tratamentos. A inclusão de ureia não influencia o balanço de nitrogênio, porém eleva as concentrações de N-amoniacal no rúmen e N-ureico no plasma podendo influenciar o gasto de energia no organismo.

The goal of this study was to evaluate the effects of including urea in diets containing mesquite pod meal on nitrogen balance, plasma urea-N and ruminal parameters. Eight gelded males, with mean weight of 33.5 kg, were divided into two 4 x 4 Latin squares. Treatments consisted of following urea levels in diet: 0, 0.5, 1.0 and 1.5% of total dry matter. The diet was provided as total diet a 40:60 forage: concentrate ratio based on total diet DM. Total urine and feces were collected and nitrogen excretion was determined. Blood was collected, followed by plasma extraction and quantification of urea nitrogen. To evaluate pH and ammonia-N in rumen fluid, four rumen fistulated animals were used . Intake of N (31.68 g day-1) and losses through feces (7.94 g day-1) and urine (9.95 g day-1) did not change. The concentrations of ammonia-N and plasma urea-N increased linearly. Rumen pH was similar among treatments. The inclusion of urea does not influence the nitrogen balance, but increases the concentrations of rumen ammonia-N and urea nitrogen in plasma, which may influence energy expenditure in the body.

This paper presents a study on the compressive behavior of steel fiber-reinforced concrete. In this study, an analytical model for stress-strain curve for steel fiber-reinforced concrete is derived for concretes with strengths of 40 MPa and 60 MPa at the age of 28 days. Those concretes were reinforced with steel fibers with hooked ends 35 mm long and with aspect ratio of 65. The analytical model was compared with some experimental stress-strain curves and with some models reported in technical literature. Also, the accuracy of the proposed stress-strain curve was evaluated by comparison of the area under stress-strain curve. The results showed good agreement between analytical and experimental data and the benefits of the using of fibers in the compressive behavior of concrete.

The aim of this research is to understand the nurses toward teenage pregnancy. It was carried out, in a first moment, a conceptual approach about the theme and, the phenomenology universe in Maurice Merleau-Ponty for theoretical methodological referential. Five nurses who work in Basic Health Units in Cascavel - Paraná, were the study subjects. The data collection instrument was prepared with a research question. The interviews were carried out from October to December of 2006. The amount of people interviewed was according to the convergences that were showed. The descriptions were recorded and transcribed. Four theme Units were identified: for the nurses, the teenage body is seen as object of desire and sexual use; the job of the multi-professional team is about the care as corporeity; the responsible paternity can be possible in a context of information through the language among the team, relatives or responsible and the teenagers; the teenager, as a living body, also suffers the effects of the environment. The care among the pregnant teenagers is understood as an action that goes beyond the technical procedures, it includes involvement and commitment with the other

Este estudio tuvo como objetivo comprender los enfermeros frente al embarazo en la adolescencia, en un primer momento fue realizado un abordaje conceptual sobre la temática y, como referencial teórico metodológico, el universo de la fenomenología en Maurice Merleau-Ponty. Los sujetos del estudio fueron cinco enfermeros que actúan en Unidades Básicas de Salud en Cascavel/PR. El instrumento de recolección de datos fue elaborado con una cuestión ordenadora. Las entrevistas fueron realizadas de octubre a diciembre de 2006. La cantidad de sujetos entrevistados se dio de acuerdo con las convergencias que se presentaron. Las descripciones fueron grabadas y transcritas. Cuatro unidades temáticas fueron identificadas: 1) para los enfermeros el cuerpo de la adolescente es comprendido como objeto de deseo y de uso sexual; 2) el trabajo del equipo multiprofesional ocurre en un sentido de cuidado en cuanto corporeidad; 3) la paternidad responsable puede ser posible en el contexto de la información por medio de lenguaje entre el equipo, familiares o responsables y las adolescentes; 4) la adolescente, en cuanto cuerpo viviente, también sufre las influencias del medio. El cuidado con la adolescente embarazada es comprendido como acción que va más allá de los procedimientos técnicos, engloba envolvimiento y 3 compromiso con el otro.

Este estudo teve como objetivo identificar a percepção dos enfermeiros diante da gravidez na adolescência. No primeiro momento foi realizada uma abordagem conceitual sobre a temática e, como referencial teórico-metodológico, o universo da fenomenologia em Maurice Merleau-Ponty. Os sujeitos do estudo foram cinco enfermeiros que atuam em unidades básicas de saúde no município de Cascavel - PR. O instrumento de coleta de dados foi elaborado com uma questão norteadora. As entrevistas foram realizadas de outubro a dezembro de 2006. A definição do número de sujeitos entrevistados se deu de acordo com as convergências que se apresentaram. As descrições foram gravadas e transcritas. Quatro unidades temáticas foram identificadas: 1) para os enfermeiros, o corpo da adolescente é compreendido como objeto de desejo e de uso sexual; 2) o trabalho da equipe multiprofissional acontece num sentido de cuidado enquanto corporeidade;3) a paternidade responsável pode ser possível no contexto da informação por meio da linguagem entre a equipe multiprofissional, familiares ou responsáveis, e as adolescentes; 4) a adolescente, enquanto corpo vivente, também sofre as influências do meio. O cuidado da adolescente gestante é entendido como ação que vai além de procedimentos técnicos, englobando envolvimento e compromisso com o outro.