Abstract The university is acknowledged as an institution of great complexity, one that constantly navigates challenges in its interactions with the external community while adhering to an ethical code that defines its institutional identity and guides its research efforts. Moreover, it undertakes digital transformation processes to effectively meet its objectives. With this recognition, this article reports on the experience of designing and developing a Platform for the management of ethical and safety evaluations in scientific research, aimed at facilitating the work of ethical-scientific committees in the university environment. The methodological approach was carried out using tools typical of case study designs, working with documents and defining the following as dimensions of analysis: the development conditions of the platform, its characteristics, its future and challenges. The results indicate that in organizations that prioritize digital transformation as a process that adds value to strategy, a positive impact on knowledge management is observed, as is the case with this Platform. The significance of working with key actors, system users who execute interactions on the platform, appreciating their role in feedback processes and the improvement of the computer resource, is highlighted. Furthermore, it is noted that when there is a strategic vision of digital transformation as a process, favoring progressive development, identifying gaps and improvements in systems, enriching synergies are generated with other sectors of the institution, resulting in a profound and widespread impact throughout the university.

Resumen La universidad como institución es reconocida como una organización de gran complejidad, que constantemente navega desafíos en su interacción con la comunidad externa, al mismo tiempo que se adhiere a un código ético que define su identidad institucional y guía su labor investigativa, y que emprende procesos de transformación digital para cumplir efectivamente con sus objetivos. Con ese reconocimiento, este artículo da cuenta de la experiencia de diseño y desarrollo de una Plataforma para la gestión de la evaluación ética y de seguridad en investigación científica, destinada a facilitar el trabajo de los Comités ético-científicos en el ámbito universitario. El abordaje metodológico se realizó desde herramientas propias de los diseños de estudios de caso, trabajando con material documental y definiendo las siguientes como dimensiones de análisis: las condiciones de desarrollo de la plataforma, las características de ella, sus proyecciones y desafíos. Los resultados indican que en las organizaciones que priorizan la transformación digital como un proceso que aporta valor a la estrategia, se observa un impacto positivo en la gestión del conocimiento, tal como ocurre con esta Plataforma. Destaca la relevancia del trabajo con los actores claves, usuarios del sistema, quienes ejecutan las interacciones en la plataforma, valorando su rol en los procesos de retroalimentación y mejora del recurso informático. Además, se destaca que cuando hay una mirada estratégica de la transformación digital como proceso, favoreciendo un desarrollo progresivo, identificando brechas y mejoras en los sistemas, se generan sinergias enriquecedoras con otros sectores de la institución, generando un impacto profundo y amplio en toda la universidad.

Abstract This article analyzes the operational variables of a catalytic cracking plant that affect the catalytic circulation and conversion results. It is considered that the analysis of the impact of these variables on the catalytic circulation is essential for the refiner to determine the best operational strategies, without loss of profitability and to minimize friction mechanisms, which reduce particulate emissions. The Analysis of Variance revealed how, statistically, the parameters are related, presenting equal, opposite directions and with different magnitudes. The results of R2, F significances and analysis of residuals showed an excellent fit of the model, therefore, validating the design of the experiments carried out. The application model demonstrated a reduction capacity of 25% in the circulation of the catalyst, with no impact on the conversion of the unit. This result demonstrates the refiner's ability to act, improving its unit optimization techniques from an environmental and economic bias. strategies mechanisms emissions how statistically related equal magnitudes R2 R therefore out 25 catalyst refiners s act bias 2

Abstract Effector proteins in Phakopsora pachyrhizi (Pp), the causative agent of Asian Soybean rust, are involved in the infection process. A previous study identified a rust effector Egh16-like family based expression profile during the interaction with soybean. Herein, we scrutinized available the Pp genomes to validate the predicted Egh16-like family of Pp and identify new family members. We described 22 members of the Egh16-like gene family in the Pp MT2006 genome and 18 in the UFV02 and K8108 genomes, highlighting a family expansion. Family members have a small signal peptide, conserved cysteine-rich R/Y/FxC motifs in the C-terminal region, and a virulence-related Egh16-like domain and were able to suppress PTI related responses in Benthamiana. Phylogenetic analysis placed the family members into eight clusters, with members induced during the early stages of rust infection. Members of clusters VI and VII are present in different copy numbers in Pp genomes and suppressed PAMP-related responses. Pp, , (Pp) process Egh16like Eghlike Egh16 like Egh soybean Herein 2 MT MT200 1 UFV UFV0 K K810 expansion peptide cysteinerich cysteine rich RYFxC R Y FxC Cterminal C terminal region virulencerelated virulence Benthamiana PAMPrelated PAMP (Pp Egh1 MT20 K81 MT2 K8

ABSTRACT BACKGROUND AND OBJECTIVES: Individuals with osteoarthritis (OA) often have joint pain and are overweight or obese. Thus, the objective of this study was to observe whether there is correlation between body mass index and joint pain intensity with gait performance in individuals with OA. METHODS: Cross-sectional study, which evaluated 60 volunteers, being 30 with clinical diagnosis of knee osteoarthritis and 30 without the disease, of both sexes and aged between 50-82 years. Joint pain intensity was assessed using the Visual Analog Scale, gait-related functional tasks using the Dynamic Gait Index, and the functional mobility using the Timed Up and Go test. RESULTS: There was a correlation between overweight/obesity and high levels of joint pain intensity (p=0.018), with worse performance in gait-related functional tasks (p=0.000) and with worse functional mobility (p=0.034) only for the individuals with OA. High levels of joint pain intensity also correlated with worse performance in the gait-related functional tasks (p=0.000) in the OA group, and also with worse functional mobility in the OA group (p=0.001) and also in the group of individuals without the disease (p=0.032). CONCLUSION: This study identified a correlation between overweight/obesity and high levels of joint pain intensity and worse gait performance in individuals with osteoarthritis. High levels of pain intensity also correlated with worse gait performance in individuals with OA. OBJECTIVES (OA obese Thus METHODS Crosssectional Cross sectional 6 volunteers 3 5082 50 82 50-8 years Scale gaitrelated related Index test RESULTS overweightobesity obesity p=0.018, p0018 p p=0.018 , 0 018 (p=0.018) p=0.000 p0000 000 (p=0.000 p=0.034 p0034 034 (p=0.034 p=0.001 p0001 001 (p=0.001 p=0.032. p0032 p=0.032 . 032 (p=0.032) CONCLUSION 508 5 8 50- p001 p=0.01 01 (p=0.018 p=0.00 p000 00 (p=0.00 p=0.03 p003 03 (p=0.03 (p=0.032 p00 p=0.0 (p=0.01 (p=0.0 p0 p=0. (p=0. p=0 (p=0 p= (p= (p

resumo JUSTIFICATIVA E OBJETIVOS: Indivíduos com osteoartrite (OA) frequentemente apresentam dor articular e sobrepeso ou obesidade. Assim, o objetivo deste estudo foi observar se existe correlação entre o índice de massa corporal e a intensidade da dor articular com o desempenho da marcha em indivíduos com OA. MÉTODOS: Estudo de corte transversal, que avaliou 60 indivíduos, sendo 30 com diagnóstico clínico de osteoartrite de joelho e 30 sem a doença, de ambos os sexos e com faixa etária entre 50 e 82 anos. A intensidade da dor articular foi avaliada pela Escala Analógica Visual, as tarefas funcionais relacionadas à marcha pelo Dynamic Gait Index e a mobilidade funcional pelo teste Timed Up and Go. RESULTADOS: Houve correlação entre o sobrepeso/obesidade e níveis elevados de intensidade da dor articular (p=0,018), com um pior desempenho nas tarefas funcionais relacionadas à marcha (p=0,000) e com menor mobilidade funcional (p=0,034) apenas para os indivíduos com OA. Os níveis elevados de intensidade de dor articular também mostraram correlação com um pior desempenho nas tarefas funcionais relacionadas à marcha (p=0,000) no grupo com OA, e ainda, com uma menor mobilidade funcional no grupo com OA (p=0,001) e também no grupo de indivíduos sem a doença (p=0,032). CONCLUSÃO: Este estudo identificou correlação entre o sobrepeso/obesidade com níveis elevados de intensidade da dor articular e com um pior desempenho na marcha nos indivíduos com OA. Os elevados níveis de intensidade da dor também mostraram correlação com pior desempenho na marcha nos indivíduos com OA. OBJETIVOS (OA obesidade Assim MÉTODOS transversal 6 3 5 8 anos Visual Go RESULTADOS sobrepesoobesidade p=0,018, p0018 p p=0,018 , 0 018 (p=0,018) p=0,000 p0000 000 (p=0,000 p=0,034 p0034 034 (p=0,034 ainda p=0,001 p0001 001 (p=0,001 p=0,032. p0032 p=0,032 . 032 (p=0,032) CONCLUSÃO p001 p=0,01 01 (p=0,018 p=0,00 p000 00 (p=0,00 p=0,03 p003 03 (p=0,03 (p=0,032 p00 p=0,0 (p=0,01 (p=0,0 p0 p=0, (p=0, p=0 (p=0 p= (p= (p

RESUMO O objetivo da pesquisa foi promover uma dinâmica de construção e recuperação da memória histórica que identifique e documente as vozes das vítimas do conflito armado no distrito de Riachuelo, Santander; por meio da metodologia qualitativa de pesquisa-ação participativa e utilizando a observação, entrevistas semiestruturadas e oficinas coletivas como instrumentos de coleta de informações. Como resultado, apresenta-se a caracterização das narrativas dos moradores do Riachuelo sobre três lugares representativos do território e nos quais, durante o conflito, os paramilitares exerceram o controle. Atualmente, os habitantes do corregimiento estão relutantes em falar sobre o passado violento, dadas as diferentes interpretações e afetações que deixou para trás; no entanto, eles compartilham narrativas sobre El Salto, o Colegio e a iglesia como imaginários culturais, evitando significados mais profundos por meio de narrativas mitico-religiosas.

ABSTRACT The aim of the research was to promote a dynamic of construction and recovery of historical memory that identifies and documents the voices of the victims of the armed conflict in the district of Riachuelo, Santander. The methodology was the qualitative participatory action research in whose frame were used three instruments for collecting information: observation, semi-structured interviews and collective workshops. As a result, is presented the characterization of the narrations that Riachuelo's inhabitants make about three representative places of the territory and in which, during the conflict, the paramilitaries exercised control. Currently, the inhabitants of this jurisdiction are reluctant to talk about the violent past, given the different interpretations and affectations that it left behind; however, they share narratives about El Salto, the school and the church as cultural imaginaries, avoiding deeper meanings through mythical-religious narratives.

RESUMEN La investigación tuvo como objetivo propiciar una dinámica de construcción y recuperación de la memoria histórica que identifique y documente las voces de las víctimas del conflicto armado del corregimiento de Riachuelo, Santander. La metodologia que guio el proceso fue la investigación acción participativa, de corte cualitativo; además, se usaron tres instrumentos de recolección de información: observación, entrevista semiestructurada y talleres colectivos. Como resultado se presenta la caracterización de las narraciones que los habitantes del corregimiento hacen sobre tres lugares representativos del territorio y en los cuales, durante el conflicto, ejercieron control los grupos paramilitares. En la actualidad, los habitantes del corregimiento se tornan renuentes a conversar sobre el pasado violento, dadas las diferentes interpretaciones y afectaciones que este dejó; no obstante, comparten narraciones sobre El Salto, el colegio y la iglesia como imaginarios culturales, soslayando significados más profundos a través de narraciones mitico-religiosas.

RESUMEN Objetivo: Analizar espiritualidad en el proceso de la incertidumbre de la enfermedad en el paciente oncológico. Métodos: Investigación cualitativa, en la cual fue utilizada como referencial teórico la Teoría de la Incertidumbre Frente a la Enfermedad, de Merle Mishel; y como referencial metodológico, las etapas del Análisis de Contenido de Bardin. Como técnica de obtención de las informaciones, fue usada la entrevista semiestructurada. Resultados: La espiritualidad en la incertidumbre de la enfermedad varia de paciente para paciente y actúa de manera singular. Ellos presentaron actitudes de readaptación en sus relatos. La presencia de la espiritualidad en sus vidas actuó como el principal mecanismo de fuerza para lidiar con la incertidumbre de la enfermedad, siendo, eso momento, llamado por Mishel de “pensamiento probabilístico”. Conclusión: Los pacientes demostraron actitudes de readaptación en sus relatos, y la espiritualidad actuó como el principal mecanismo de fuerza para lidiar con la incertidumbre en la enfermedad. Objetivo oncológico Métodos cualitativa Enfermedad metodológico Bardin informaciones semiestructurada Resultados singular relatos siendo momento pensamiento probabilístico. probabilístico . probabilístico” Conclusión

ABSTRACT Objective: To analyze spirituality in the process of illness uncertainty in cancer patients. Methods: This is a qualitative study, in which Merle Mishel’s Theory of Uncertainty of Disease was used as a theoretical framework; and as a methodological reference, the stages of Bardin’s Content Analysis. As a technique for obtaining information, a semi-structured interview was used. Results: Spirituality in the uncertainty of the disease varies from patient to patient and acts in a unique way. They presented readaptation attitudes in their reports. The presence of spirituality in their lives acted as the main force mechanism to deal with the uncertainty of the disease, and this moment was called by Mishel “probabilistic thinking”. Conclusion: Patients demonstrated readaptation attitudes in their reports, and spirituality acted as the main mechanism of strength to deal with uncertainty in the disease Objective patients Methods study Mishels s framework reference Bardins Bardin Analysis information semistructured semi structured Results way reports probabilistic thinking. thinking . thinking” Conclusion

RESUMO Objetivo: Analisar a espiritualidade no processo da incerteza da doença no paciente oncológico. Métodos: Trata-se de uma pesquisa qualitativa, na qual foi utilizada como referencial teórico a Teoria da Incerteza da Doença, de Merle Mishel; e como referencial metodológico, as etapas da Análise de Conteúdo de Bardin. Como técnica de obtenção das informações, foi usada a entrevista semiestruturada. Resultados: A espiritualidade na incerteza da doença varia de paciente para paciente e atua de forma singular. Eles apresentaram atitudes de readaptação nos seus relatos. A presença da espiritualidade em suas vidas agiu como o principal mecanismo de força para lidar com a incerteza da doença, sendo, esse momento, chamado por Mishel de “pensamento probabilístico”. Conclusão: Os pacientes demonstraram atitudes de readaptação nos seus relatos, e a espiritualidade atuou como o principal mecanismo de força para lidar com a incerteza na doença. Objetivo oncológico Métodos Tratase Trata se qualitativa Doença metodológico Bardin informações semiestruturada Resultados singular relatos sendo momento pensamento probabilístico. probabilístico . probabilístico” Conclusão

Resumo Quando uma criança nasce intersexo, demanda análise diferenciada do padrão identitário classificatório sexo masculino-feminino. O presente artigo visa discutir a garantia ao registro civil da criança intersexo na perspectiva do direito à identidade. Metodologia de natureza qualitativa: revisão de literatura, revisão legislativa e entrevista semiestruturada. A tendência da produção científica não privilegia o direito à identidade da criança intersexo. Ainda não é possível identificar um caminho legislativo específico e mais eficaz.

Abstract When a child is born intersex, it demands a different analysis of the male-female classificatory identity pattern. This article aims to discuss the guarantee to the civil registry of the intersex child from the perspective of the right to identity. Qualitative methodology: literature review, legislative review and semi-structured interview. The trend of scientific production does not favor the right to the identity of the intersex child. It is not yet possible to identify a specific and more effective legislative path.

Abstract Objective: Implement a Project to reform the health system of the Democratic Republic of Timor Leste in the period 2013-2016. Materials and methods: A research / action type study was carried out from a managerial perspective. A non-probabilistic sample was included for the convenience of users, suppliers and officials, qualitative techniques such as focus groups and open interviews were used, as well as the use of management tools. Results: In a first phase, the situational analysis was carried out at the country level. With these elements, the strategic priorities, objectives, indicators and goals were successively defined for each perspective. Finally, the change program was organized, the transformation process was carried out and the results were determined. The National Cancer Program and the National Primary Care Program were designed and kept functioning; Missing medical specialties and care services were introduced; New approaches to human resource management were created and the level of scientific work was raised, among other benefits. Conclusions: There were substantial improvements in the health system and in addition, a potential capacity was created so that these effects continue to grow in quantity and quality.

Resumen Objetivo: Implementar un proyecto de reformas al sistema de salud de la República Democrática de Timor Leste, en el periodo 2013-2016. Materiales y métodos: Se realizó un estudio de tipo investigación/acción desde una perspectiva gerencial. Se incluyó muestra no probabilística por conveniencia de usuarios, proveedores y funcionarios, se emplearon técnicas cualitativas como grupos focales y entrevistas abiertas, así como el uso de herramientas gerenciales. Resultados: En una primera fase se realizó el análisis situacional a escala de país. Con estos elementos se definieron sucesivamente las prioridades estratégicas, los objetivos, indicadores y metas por cada perspectiva. Finalmente, el programa de cambios se organizó, se ejecutó el proceso de transformaciones y se fueron determinando los resultados. Se diseñaron y quedaron funcionando el Programa Nacional de Cáncer y el Programa Nacional de Atención Primaria; se introdujeron especialidades médicas y servicios asistenciales con los que no se contaba; se crearon nuevos enfoques para la gestión de los recursos humanos y, se elevó el nivel del trabajo científico, entre otros beneficios. Conclusiones: Se produjeron mejoras sustanciales en el Sistema de Salud y además se dejó creada una capacidad potencial para que dichos efectos sigan creciendo en cantidad y calidad.

Abstract The study of the diagonal entries of the combined matrix of a nonsingular matrix A has been considered by different authors for the classes of M-matrices, positive definite matrices and totally positive (negative) matrices. This problem appears to be difficult as the results have been done only for matrices of order three. In this work, we continue to give the characterization of the diagonal entries of the combined matrix of the remainder sign regular matrices. Thus, the problem is closed for all possible sign regular matrices of order three.

Resumo Descreve-se uma atividade pedagógica com estudantes do Mestrado e Pós-Licenciatura em Enfermagem de Saúde Materna e Obstetrícia, aplicando princípios da prática simulada na realização da sutura perineal após o parto. Este procedimento causa muita insegurança e gera grande ansiedade nos estudantes, quando iniciam estágio em bloco de partos. Os objetivos deste artigo são desenvolver competências psicomotoras nos estudantes para a reconstituição cirúrgica perineal; aumentar a autoconfiança dos estudantes para o procedimento. Metodologia qualitativa, com 2 momentos de recolha de dados aplicados a dois cursos. Questionário com perguntas abertas, sessão de “focus group” e filmagem. Análise de conteúdo das respostas às perguntas abertas e verbatim do “focus group”. Como Resultados destaca-se uma estreita relação entre a simulação e o desenvolvimento de competências. Os estudantes salientaram a importância da atividade pedagógica na aquisição de competências de sutura, reforço da autoconfiança e na diminuição da ansiedade inicial. O uso da investigação qualitativa permitiu identificar o impacto da prática simulada no desenvolvimento de competências dos estudantes, identificar aspetos a aperfeiçoar na metodologia, contribuindo para a melhoria das práticas pedagógicas.

Abstract A pedagogical activity with Master’s Degree and Postgraduate students in Maternal Health and Obstetrics Nursing is described, applying principles of simulated practice in perineal suturing after delivery. This procedure causes a lot of insecurity and generates great anxiety in the students, when they start the internship in a delivery room. Objectives: to develop the psychomotor skills in students for perineal surgical reconstruction; increase students’ self-confidence to perform the procedure. Methodology: qualitative, with 2 moments of data collection applied to two courses. Questionnaire with open questions, focus group session and filming. Content analysis of the answers to the questions and verbatim of the focus group. Results: a close relationship was observed between simulation and skills development. Conclusion: the students emphasized the importance of the pedagogical activity in the acquisition of suturing skills, improving their self-confidence and reducing the initial anxiety. The use of the qualitative research allowed identifying the impact of the simulated practice on the development of the students’ skills and to identify aspects to be improved, contributing to the progress of pedagogical practices.

Resumo Descreve-se uma atividade pedagógica com estudantes do Mestrado e Pós-Licenciatura em Enfermagem de Saúde Materna e Obstetrícia, aplicando princípios da prática simulada na realização da sutura perineal após o parto. Este procedimento causa muita insegurança e gera grande ansiedade nos estudantes, quando iniciam estágio em bloco de partos. Os objetivos deste artigo são desenvolver competências psicomotoras nos estudantes para a reconstituição cirúrgica perineal; aumentar a autoconfiança dos estudantes para o procedimento. Metodologia qualitativa, com 2 momentos de recolha de dados aplicados a dois cursos. Questionário com perguntas abertas, sessão de “focus group” e filmagem. Análise de conteúdo das respostas às perguntas abertas e verbatim do “focus group”. Como Resultados destaca-se uma estreita relação entre a simulação e o desenvolvimento de competências. Os estudantes salientaram a importância da atividade pedagógica na aquisição de competências de sutura, reforço da autoconfiança e na diminuição da ansiedade inicial. O uso da investigação qualitativa permitiu identificar o impacto da prática simulada no desenvolvimento de competências dos estudantes, identificar aspetos a aperfeiçoar na metodologia, contribuindo para a melhoria das práticas pedagógicas.

Abstract A pedagogical activity with Master’s Degree and Postgraduate students in Maternal Health and Obstetrics Nursing is described, applying principles of simulated practice in perineal suturing after delivery. This procedure causes a lot of insecurity and generates great anxiety in the students, when they start the internship in a delivery room. Objectives: to develop the psychomotor skills in students for perineal surgical reconstruction; increase students’ self-confidence to perform the procedure. Methodology: qualitative, with 2 moments of data collection applied to two courses. Questionnaire with open questions, focus group session and filming. Content analysis of the answers to the questions and verbatim of the focus group. Results: a close relationship was observed between simulation and skills development. Conclusion: the students emphasized the importance of the pedagogical activity in the acquisition of suturing skills, improving their self-confidence and reducing the initial anxiety. The use of the qualitative research allowed identifying the impact of the simulated practice on the development of the students’ skills and to identify aspects to be improved, contributing to the progress of pedagogical practices.

Abstract INTRODUCTION: Parasitic infections are considered a major public health problem due to their associated morbimortality and negative impact on physical and intellectual development, especially in the at-risk pediatric group. Periodic prophylactic administration of antiparasitic agents against soil-transmitted helminths is recommended by the World Health Organization (WHO) to control parasitic infections and disease burden. We aimed to evaluate the prevalence of intestinal parasitic infections in Brazil. METHODS: We performed a systematic review by searching the literature found in the PubMed, LILACS, and SciELO databases, followed by a meta-analysis of the proportions from studies published in English, Portuguese, and/or Spanish from January 2000 to May 2018. This systematic review was registered in the PROSPERO database (CRD42018096214). RESULTS: The prevalence of intestinal parasitic infections (protozoa and/or helminths) in Brazil was 46% (confidence interval: 39-54%), with 99% heterogeneity. Prevalence varied by region: 37%, 51%, 50%, 58%, and 41% in the Southeast, South, Northeast, North, and Central-West regions, respectively. Most studies (32/40) evaluated children (<18 years) and found an average prevalence of 51%. Children also had the highest prevalence in all four regions: Central-West (65%), South (65%), North (58%), Northeast (53%), and Southeast (37%). However, most studies evaluated specific populations, which may have created selection bias. Presumably, this review of intestinal parasitic diseases in Brazil includes the most studies and the largest population ever considered. CONCLUSIONS The prevalence of intestinal parasitic infections is high in Brazil, and anthelmintic drugs should be administered periodically as a prophylactic measure, as recommended by the WHO.

ABSTRACT Introduction: Leptospirosis is an infectious disease caused by pathogenic Leptospira sp. bacteria. It affects a large number of mammals, including humans, and is considered to be one of the most widely distributed zoonotic diseases worldwide. Objective: Determine the seroprevalence of antibodies against Leptospira spp. and the risk factors associated to leptospirosis in some pig populations from Portoviejo. Methods: A descriptive study was conducted from October 2018 to March 2019 of pigs raised in parishes from Portoviejo Canton in Manabí, Ecuador. A total 280 blood samples were collected (115 from pigs raised technically and 165 from pigs raised in backyards), 140 in the rainy season (January-March) and 140 in the dry season (October-December), so that the samples were representative of the two seasons. Serological diagnosis was performed with the microscopic agglutination test. Results: In technical breeding, seroprevalence was 16.52% (19/115), whereas in backyard breeding it was 20.61% (34/165). It was most common in serovars Australis and Icterohaemorrhagiae, with 14.28% (40/280), respectively, and Bataviae with 13.21% (37/280). Risk associated to Leptospira infection was greater in sows, in pig populations which drank river water, and in areas where wild rodent control was not present. Conclusions: Seroprevalence of antibodies against Leptospira spp. was moderate in technical and backyard pig raising populations, but it is a potential hazard for the human population exposed. In both breeding systems, the most common serovars were Australis, Icterohaemorrhagiae and Bataviae.

RESUMEN Introducción: La leptospirosis es una enfermedad infecciosa bacteriana causada por leptospiras patógenas, que afectan a una amplia variedad de mamíferos incluido el hombre. Es considerada como una de las enfermedades zoonóticas de mayor distribución a nivel mundial. Objetivo: Determinar la seroprevalencia de anticuerpos contra Leptospira spp. y factores de riesgo asociados a la leptospirosis en algunas poblaciones de cerdos de Portoviejo. Métodos: Estudio descriptivo, realizado entre octubre de 2018 a marzo de 2019. Se estudiaron cerdos criados en parroquias del cantón Portoviejo, Manabí, Ecuador. Se colectaron un total de 280 muestras de sangre (115 de cerdos en crianza tecnificada y 165 en crianza de traspatio), 140 en el periodo lluvioso (enero-marzo) y 140 en el periodo seco (octubre-diciembre), de forma tal que fueran representativos los animales para ambas épocas. El diagnóstico serológico se realizó mediante la prueba de aglutinación microscópica. Resultados: En la crianza tecnificada, la seroprevalencia fue de 16,52 % (19/115) y en la crianza de traspatio, 20,61 % (34/165). Se presentó con mayor frecuencia en serovares Australis e Icterohaemorrhagiae en 14,28 % (40/280), respectivamente, y Bataviae en 13,21 % (37/280). El riesgo asociado a la infección por leptospiras fue mayor en los cerdos del sexo femenino, en las poblaciones de cerdos que consumieron agua de ríos y en los predios donde no se realizó un control de roedores silvestres. Conclusiones: La seroprevalencia a anticuerpos contra Leptospira spp. en la población de cerdos en crianza tecnificada y traspatio fue moderada, pero constituye un peligro potencial para la población humana expuesta. En ambos sistemas de crianza, los serovares más frecuentes fueron Australis, Icterohaemorrhagiae y Bataviae.

ABSTRACT Introduction: Infections in the skin and soft tissues are common health concerns in children, with a wide range of severity from patient to patient. Objective: To describe the clinical-epidemiological characteristics of the patients with soft tissue infections hospitalized in the Pediatric Teaching Hospital “Hermanos Cordové”. Method: An observational, descriptive, cross-sectional study was carried out in the services of pediatric clinic in the Pediatric Teaching Hospital “Hermanos Cordové”, in Manzanillo, Cuba, during the year 2018. All discharged patients who had a confirmed diagnosis of this type of infection were studied (n=298). The following variables were taken into account: anatomical location, classifications of the different types of skin and soft tissue infections, treatment used and hospitalization. Results: Male gender prevailed in the patients (57.7 %), and also the ages ranging between 10 to 14 years old (34.9 %). Infections located on the limbs were described in 113 patients (37.9 %). Impetigo was the most common diagnosis (42.3 %), and the most frequently used antibiotic was cefazolin (77.2 %). Most of the patients were hospitalized up to 7 days (293), with a satisfactory evolution of the disease. Conclusions: Patients with soft tissue infections in the services of pediatric clinic in the Pediatric Teaching Hospital “Hermanos Cordové” are mainly characterized for being male, especially from ages raging between 10 to 14 years old, with impetigo being the most common infection, mostly located on the limbs. Cefalozin resulted very effective for the treatment of these infections, making possible the hospitalization time to be lesser than a week.

RESUMEN Introducción: Las infecciones de la piel y partes blandas son frecuentes en los niños, con un amplio espectro de gravedad. Objetivo: Describir las características clínico-epidemiológicas de los pacientes con infecciones de partes blandas superficiales hospitalizados en el servicio de clínicas pediátricas del Hospital Pediátrico Docente “Hermanos Cordové”. Método: Se realizó un estudio observacional, descriptivo y transversal en el servicio de clínicas pediátricas del Hospital Pediátrico Docente “Hermanos Cordové”, de Manzanillo durante el 2018.Se estudiaron todos los pacientes egresados (n=298) con el diagnóstico confirmado de este tipo de infecciones. Se tomaron en cuenta las siguientes variables: localización anatómica, clasificación del tipo deinfección de piel y tejidos blandos, terapéutica utilizada y estadía hospitalaria. Resultados: Predominó el sexo masculino (57,7 %) y el grupo de edad de 10-14 años (34,9 %). Las infecciones en las extremidades estuvieron presentes en 113 pacientes (37,9 %). El impétigo fue la entidad clínica más frecuente (42,3 %), la cefazolina fue el antibiótico más utilizado (77,2 %). Se observó que la mayoría de los pacientes (293) solo permaneció hasta 7 días ingresados, con una evolución satisfactoria. Conclusiones: En el servicio de clínicas pediátricas del Hospital Pediátrico Docente “Hermanos Cordové”, los pacientes con IPTB se caracterizan por ser sobre todo varones, más comúnmente con edad entre 10 y 14 años, las lesiones predominaron en las extremidades y la más común fue el impétigo. La cefazolina resultó eficaz para el tratamiento estas infecciones, lo que hizo posible que la estadía hospitalaria generalmente no excediera de siete días.

Resumo: Esta comunicação é centrada na nossa pesquisa e intervenção em promoção da saúde com pacientes e comunidades afetadas por diversas doenças infecciosas, no projeto Plataforma de Saberes. Esse projeto é desenvolvido no Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, no Rio de Janeiro, Brasil, e promove o envolvimento continuado de pesquisadores e profissionais de saúde na produção colaborativa de conhecimento sobre saúde com pacientes e grupos comunitários, e na sua capacitação como promotores de saúde comunitária. Face ao novo cenário epidêmico, surgiu a demanda de um espaço de diálogo e partilha de conhecimento sobre prevenção da transmissão da COVID-19. Devido à interrupção das atividades regulares do Plataforma de Saberes, foi promovida uma estratégia que servisse de elo integrador entre ciência e sociedade e ajudasse a superar o isolamento social imposto pela pandemia da COVID-19. O grupo de WhatsApp possibilitou aos integrantes do projeto participarem por meio de formulação de perguntas (áudio) sobre a COVID-19, por intermédio da mediação dos líderes de grupos comunitários. Os principais questionamentos dos participantes estão relacionados com fatores de risco; formas de transmissão; imunidade ao novo vírus; cuidados relacionados à prevenção, sintomas e tratamento; COVID-19 e vacina da influenza. O material educativo Cuidar em tempos da COVID-19 foi produzido e compartilhado com os líderes comunitários e disponibilizado aos respectivos grupos, e veio a ser disseminado nas suas comunidades como resposta a uma demanda de conhecimento que responde às preocupações vividas pelos que já se encontram em situação de vulnerabilidade estrutural.

Abstract: This paper focuses on our research and intervention in health promotion with patients and communities affected by various infectious diseases, in the project Knowledge-Sharing Platform. This project is developed at the National Institute of Infectious Diseases Evandro Chagas in the Oswaldo Cruz Foundation, Rio de Janeiro, Brazil, and promotes the continuing involvement of health researchers and professionals in the collaborative production of knowledge on health with patients and community groups and in their training as community health promoters. The new epidemic scenario created the demand for a space of dialogue and knowledge-sharing on the prevention of COVID-19 transmission. Due to the interruption of regular activities in the Knowledge-Sharing Platform, a strategy was launched to serve as a link between science and society and help overcome the social isolation imposed by the COVID-19 pandemic. The WhatsApp group allowed project members to participate by addressing questions (audio) on COVID-19 through mediation by community group leaders. The main questions by participants related to risk factors, transmission, immunity to the novel coronavirus, care related to prevention, symptoms, and treatment; and COVID-19 and influenza vaccine. The educational material Caring in the Age of COVID-19 was produced and shared with community leaders and distributed to the respective groups and was eventually shared in their communities as a response to a demand for knowledge that responds to the concerns of people already exposed to structural vulnerability.

Resumen: Esta comunicación se centra en nuestra investigación e intervención en la promoción de la salud con pacientes y comunidades afectadas por diversas enfermedades infecciosas, en el proyecto Plataforma de Saberes. Este proyecto está desarrollado en el Instituto Nacional de Infectología Evandro Chagas/Fundación Oswaldo Cruz, en Río de Janeiro, Brasil, y promueve la implicación continuada de investigadores y profesionales de salud en la producción colaborativa de conocimiento sobre salud con pacientes y grupos comunitarios, y en su capacitación como promotores de salud comunitaria. Frente al nuevo escenario epidémico, surgió la demanda de un espacio de diálogo e intercambio de conocimiento sobre la prevención de la transmisión de la COVID-19. Debido a la interrupción de las actividades regulares de la Plataforma de Saberes, se promovió una estrategia que sirviese de vínculo integrador entre ciencia y sociedad y ayudase a superar el aislamiento social impuesto por la pandemia de la COVID-19. El grupo de WhatsApp posibilitó a los integrantes del proyecto, que participaran mediante la formulación de preguntas (audio) sobre la COVID-19, a través de la mediación de los líderes de grupos comunitarios. Los principales cuestionamientos de los participantes se relacionaron con factores de riesgo; formas de transmisión; inmunidad ante el nuevo virus; cuidados relacionados con la prevención, síntomas y tratamiento; COVID-19 y vacuna de la gripe. El material educativo Cuidar em tempos da COVID-19 se produjo y se compartió con los líderes comunitarios y fue puesto a disposición de los respectivos grupos, así como difundido en sus comunidades, en respuesta a una demanda de conocimiento que responde a las preocupaciones vividas por los que ya se encuentran en situación de vulnerabilidad estructural.