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Resumo O diagnóstico do ceratoacantoma é desafiador e, portanto, esta publicação contribui para a literatura atual apresentando dados epidemiológicos e descrevendo características clínicas e histopatológicas e a decisão de tratamento. Homem caucasiano de 69 anos apresentava nódulo de crescimento exofítico em lábio inferior, de 10 mm, bem delimitado, de forma circular, consistência firme, cor rósea e superfície rugosa. A suspeita clínica foi de carcinoma de células escamosas. Foi realizada biópsia incisional e análise histopatológica, a qual revelou fragmentos de mucosa oral revestidos por epitélio pavimentoso estratificado hiperparaceratinizado com centro preenchido por ceratina, pérolas córneas, hiperplasia pseudoepiteliomatosa e áreas de displasia epitelial, concluindo o diagnóstico de ceratoacantoma. Foi feita a ressecção cirúrgica, removendo totalmente a lesão. A análise histopatológica confirmou o diagnóstico de ceratoacantoma. Indivíduos do sexo masculino, caucasianos, acima de 45 anos de idade são os mais acometidos pelo ceratoacantoma. A histopatologia do caso corrobora a caracterização clássica, principalmente a depressão central preenchida por ceratina. O tratamento escolhido foi a ressecção cirúrgica com pequena margem de segurança, de acordo com a literatura atual. Os ceratoacantomas são mais comuns em indivíduos do sexo masculino com idade acima de 45 anos. O principal fator etiológico é a exposição solar sem medidas de proteção. Esta lesão apresenta-se como nódulo exofítico, de consistência firme, superfície rugosa e centro preenchido por ceratina. A histopatologia caracteriza-se por estrutura crateriforme, disceratose e presença de pérolas córneas. O tratamento mais indicado é a ressecção cirúrgica.

Abstract Keratoacanthoma diagnosis is challenging, and therefore, this publication contributes to the current literature by presenting epidemiological data and describing clinical and histopathological characteristics and the treatment decision. A 69-year-old Caucasian male patient presented with a well-delimited exophytic growth nodule in the lower lip measuring 10 millimeters with circular shape, firm consistency, pink color, and rough surface. The clinical suspicion was squamous cell carcinoma. An incisional biopsy and histopathological analysis were performed, which revealed fragments of oral mucosa lined by hyperparakeratinized stratified squamous epithelium with a center filled with keratin, corneal pearls, pseudoepitheliomatous hyperplasia, and areas of epithelial dysplasia. The diagnosis of keratoacanthoma was determined. Surgical resection was performed, completely removing the lesion, and histopathological analysis confirmed the diagnosis of keratoacanthoma. The fact that the patient was male, over 45 years old, and Caucasian agrees with the epidemiology of the population most affected by keratoacanthoma. The histopathology of the case corroborates the classic characterization, mainly the central depression filled with keratin. The treatment chosen was surgical resection with a small margin of safety, according to the current literature. Keratoacanthomas are more common in males aged over 45 years and in Caucasian individuals. The main etiology is sun exposure without protective measures. It presents as an exophytic nodule with a firm consistency, rough surface, and center filled with keratin. Histopathology is characterized by a crateriform structure, dyskeratosis, and the presence of corneal pearls. The most indicated treatment is surgical resection.

https://doi.org/10.24873/j.rpemd.2024.10.1225

Soil organic phosphorus in Eucalyptus plantations, Brazil: extraction methods
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Alvarenga, Laís Chierici Bernardes Rinaldi

; Costa, Marlon Gomes da

; Gama-Rodrigues, Antonio Carlos

; Aleixo, Seldon

; Gama-Rodrigues, Emanuela Forestieri

; Gonçalves, José Leonardo de Moraes

Scientia Agricola

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2024, Volume 81 elocation e20220131

Resumo: En | Texto: En | PDF: En

ABSTRACT In-depth knowledge of total soil organic phosphorus (TPO) as a potential P source for plants allows for a comprehensive understanding of the adoption of an efficient management system of phosphorus fertilization in forest plantations. Thus, we aimed to compare three TPO extraction methods (Hedley; Bowman; Bowman and Moir) in different Eucalyptus plantations on strongly weathered soils. The TPO concentrations obtained by the “Hedley” (mean of 130 mg kg–1), and “Bowman and Moir” methods (mean of 131 mg kg–1) were similar. The “Bowman” method extracted less than 50 % of the TPO content extracted by the other methods. Both “Hedley” and “Bowman and Moir” methods showed similar TPO extraction efficiency compared to TP determined by acid digestion. However, the “Hedley” method is the most expensive and time-consuming analytical technique. In view of this, the NaOH+Na2EDTA extractor (Bowman and Moir) would be the most suitable since, in addition to showing high extraction efficiency, it offers fast analysis execution, low analytical error, and lower cost.

https://doi.org/10.1590/1678-992x-2022-0131

Geography and public health: analysis of the epidemiological dynamics of meningitis in Brazil, between 2010 and 2019
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Silva, Luis Roberto da

; Arruda, Laís Eduarda Silva de

; Barreto, Isabel de Jesus Brandão

; Aragão, João Victor Rodrigues de

; Silva, Maria Luiza Ferreira Imburana da

; Lira, Guilherme

; Teixeira, Camila Maria Barros

; Oliveira, Emília Carolle Azevedo de

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240031

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1980-549720240031

Geography and public health: analysis of the epidemiological dynamics of meningitis in Brazil, between 2010 and 2019 health Brazil 201 20 2
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Silva, Luis Roberto da

; Arruda, Laís Eduarda Silva de

; Barreto, Isabel de Jesus Brandão

; Aragão, João Victor Rodrigues de

; Silva, Maria Luiza Ferreira Imburana da

; Lira, Guilherme

; Teixeira, Camila Maria Barros

; Oliveira, Emília Carolle Azevedo de

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240031

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To analyze the spatiotemporal epidemiological dynamics of meningitis in Brazil, between 2010 and 2019. Methods: Descriptive ecological study with cases and deaths due to meningitis in Brazil (2010-2019) in the National Notifiable Diseases Information System (Sistema de Informações de Agravos de Notificação – SINAN). The following analyses were performed: (I) frequency analyses of cases and deaths, prevalence rates, mortality, lethality, Fisher's exact test, and chi-square test; (II) Prais-Winstein regression; and (III) Global, Local Moran's index, and Kernel density. Results: 182,126 cases of meningitis were reported in Brazil, of which 16,866 (9.26%) resulted in death, with prevalence rates of 9.03/100,000 inhabitants, mortality of 0.84/100,000 inhabitants, and lethality of 9.26%. There was a noted trend of decreasing prevalence rates (−9.5%, 95% confidence interval — 95%CI −13.92; −4.96, p<0.01) and mortality (−11.74%, 95%CI −13.92; −9.48, p<0.01), while lethality remained stable (−2.08%, 95%CI −4.9; 0.8; p<0.1941). The majority of cases were viral meningitis (45.7%), among 1-9 years old (32.2%), while the highest proportion of deaths was due to bacterial meningitis (68%), among 40-59 years old (26.3%). In the Moran and Kernel maps of prevalence and mortality rates, municipalities in the South, Southeast, and the capital of Pernambuco in the Northeast stood out with high rates; as for lethality, the North, Northeast, and Southeast coastal areas were highlighted. Conclusion: A decrease in meningitis cases and deaths was found in this study; however, the lethality rate was higher in areas with lower prevalence, emphasizing the need to enhance actions for identifying, monitoring, and providing health care for cases, as well as expanding vaccination coverage. Objective 201 2019 Methods 20102019 (2010-2019 Sistema SINAN. SINAN . SINAN) performed I (I Fishers Fisher s test chisquare chi square II (II PraisWinstein Prais Winstein regression III (III Global Morans index density Results 182126 182 126 182,12 16866 16 866 16,86 9.26% 926 9 26 (9.26% death 903100000 03 100 000 9.03/100,00 inhabitants 084100000 0 84 0.84/100,00 −9.5%, 95 5 (−9.5% 95CI CI −13.92 1392 13 92 496 4 96 −4.96 p<0.01 p001 p 01 −11.74%, 1174 11 74 (−11.74% 948 48 −9.48 p<0.01, , −2.08%, 208 2 08 (−2.08% −4.9 49 0.8 8 p<0.1941. p01941 p<0.1941 1941 p<0.1941) 45.7%, 457 45.7% 45 7 (45.7%) 19 1 1- 32.2%, 322 32.2% 32 (32.2%) 68%, 68 68% (68%) 4059 40 59 40-5 26.3%. 263 26.3% 3 (26.3%) South North highlighted Conclusion however identifying monitoring coverage 20 2010201 (2010-201 18212 18 12 182,1 1686 86 16,8 9.26 (9.26 90310000 10 00 9.03/100,0 08410000 0.84/100,0 −9.5% (−9.5 −13.9 139 p<0.0 p00 −11.74% 117 (−11.74 94 −9.4 −2.08% (−2.08 −4. 0. p0194 p<0.194 194 45.7 (45.7% 32.2 (32.2% 6 (68% 405 40- 26.3 (26.3% 201020 (2010-20 1821 182, 168 16, 9.2 (9.2 9031000 9.03/100, 0841000 0.84/100, −9.5 (−9. −13. p<0. p0 −11.74 (−11.7 −9. −2.08 (−2.0 −4 p019 p<0.19 45. (45.7 32. (32.2 (68 26. (26.3 20102 (2010-2 9. (9. 903100 9.03/100 084100 0.84/100 (−9 −13 p<0 −11.7 (−11. −9 −2.0 (−2. − p01 p<0.1 (45. (32. (6 (26. (2010- (9 90310 9.03/10 08410 0.84/10 (− −1 p< −11. (−11 −2. (−2 (45 (32 ( (26 (2010 9031 9.03/1 0841 0.84/1 −11 (−1 −2 (4 (3 (2 (201 903 9.03/ 084 0.84/ (20 90 9.03 0.84 9.0

RESUMO Objetivo: Analisar a dinâmica epidemiológica espaçotemporal das meningites no Brasil, entre os anos de 2010 e 2019. Métodos: Estudo ecológico descritivo com os casos e óbitos por meningites no Brasil (2010–2019) no Sistema de Informações de Agravos de Notificação. Realizaram-se (I) análises de frequências dos casos e óbitos, taxas de prevalência, mortalidade, letalidade, testes de exato de Fisher e qui-quadrado; (II) regressão de Prais-Winsten; e (III) índice de Moran global, local e densidade de Kernel. Resultados: Notificaram-se 182.126 casos de meningites no Brasil, dos quais 16.866 (9,26%) evoluíram para óbito, com taxas de prevalência de 9,03/100.000/habitantes, mortalidade de 0,84/100.000/habitantes e letalidade de 9,26%. Destaca-se a tendência de decrescimento das taxas de prevalência (−9,5%, intervalo de confiança de 95% — IC95% −13,92; −4,96, p<0,01) e mortalidade (−11,74%, IC95% −13,92; −9,48, p<01,01), enquanto a letalidade se manteve estacionária (−2,08%, IC95% −4,9; 0,8; p<0,1941). A maioria dos casos foi de meningites virais (45,7%), entre 1 e 9 anos (32,2%), enquanto a maior parcela dos óbitos foi por meningites bacterianas (68%), entre 40 e 59 anos (26,3%). Nos mapas de Moran e Kernel das taxas de prevalência e mortalidade, destacaram-se com altas taxas os municípios do sul, sudeste e a capital de Pernambuco, no nordeste; já na letalidade, evidenciaram-se o norte, o nordeste e o litoral do sudeste. Conclusão: Encontrou-se decréscimo dos casos e óbitos por meningites neste estudo, entretanto a taxa de letalidade foi maior em áreas com menor prevalência, reforçando a necessidade do aprimoramento das ações de identificação, vigilância e assistência em saúde dos casos, bem como da ampliação da cobertura vacinal. Objetivo 201 2019 Métodos 2010–2019 20102019 (2010–2019 Notificação Realizaramse Realizaram I (I quiquadrado qui quadrado qui-quadrado II (II PraisWinsten Prais Winsten Prais-Winsten III (III global Resultados Notificaramse Notificaram 182126 182 126 182.12 16866 16 866 16.86 9,26% 926 26 (9,26% óbito 903100000habitantes habitantes 03 100 000 9,03/100.000/habitantes 084100000habitantes 0 84 Destacase Destaca −9,5%, 95 5 (−9,5% IC95 IC −13,92 1392 13 92 496 4 96 −4,96 p<0,01 p001 p 01 −11,74%, 1174 11 74 (−11,74% 948 48 −9,48 p<01,01, p0101 p<01,01 , p<01,01) −2,08%, 208 2 08 (−2,08% −4,9 49 0,8 8 p<0,1941. p01941 p<0,1941 . 1941 p<0,1941) 45,7%, 457 45,7% 45 7 (45,7%) 32,2%, 322 32,2% 32 (32,2%) 68%, 68 68% (68%) 26,3%. 263 26,3% 3 (26,3%) destacaramse destacaram sul Pernambuco evidenciaramse evidenciaram norte Conclusão Encontrouse Encontrou estudo identificação vacinal 20 2010–201 2010201 (2010–201 18212 18 12 182.1 1686 86 16.8 9,26 (9,26 10 00 −9,5% (−9,5 IC9 −13,9 139 p<0,0 p00 −11,74% 117 (−11,74 94 −9,4 p010 p<01,0 −2,08% (−2,08 −4, 0, p0194 p<0,194 194 45,7 (45,7% 32,2 (32,2% 6 (68% 26,3 (26,3% 2010–20 201020 (2010–20 1821 182. 168 16. 9,2 (9,2 −9,5 (−9, −13, p<0, p0 −11,74 (−11,7 −9, p01 p<01, −2,08 (−2,0 −4 p019 p<0,19 19 45, (45,7 32, (32,2 (68 26, (26,3 2010–2 20102 (2010–2 9, (9, (−9 −13 p<0 −11,7 (−11, −9 p<01 −2,0 (−2, − p<0,1 (45, (32, (6 (26, 2010– (2010– (9 (− −1 p< −11, (−11 −2, (−2 (45 (32 ( (26 (2010 −11 (−1 −2 (4 (3 (2 (201 (20

https://doi.org/10.1590/1980-549720240031

Polysaccharide from Cumaru (Amburana cearensis) exudate and its potential for biotechnological applications Amburana cearensis
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Silva, José Regilmar Teixeira da

; Araújo, Iranildo Costa

; Silva, Eziel Cardoso da

; Santana, Moisés das Virgens

; Almeida, Geanderson Emilio de

; Farias, Emanuel Airton de Oliveira

; Lima, Laís Ramos Monteiro de

; Paula, Regina Célia Monteiro de

; Silva, Durcilene Alves da

; Araújo, Alyne Rodrigues

; Eiras, Carla

Polímeros

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2024, Volume 34 Nº 1 elocation e20240008

Resumo: En | Texto: En | PDF: En

Abstract Amburana cearensis tree is used in various applications, from artisanal to pharmaceutical use. However, the gum extracted from its exudate has not yet been investigated. This study aimed to the physicochemical and structural characterization of Amburana cearensis Gum (AcG) by elemental, rheological, and thermal analyses, X-ray diffraction (XRD), high-Performance Liquid Chromatography (HPLC), Gel Permeation Chromatography (GPC), Infrared Spectroscopy (FTIR), UV-Vis spectroscopy and nuclear magnetic resonance (NMR). Additionally, a hemolytic assay was performed to evaluate the biocompatibility of AcG using human erythrocytes. The results showed that AcG consists of β-D-Galactopyranose monomers linked by glycosidic bonds (1→3). At the same time, the side chains exhibit β-Galactopyranose (1→6) and α-L-Arabinofuranoside (1→3,6) monomers as non-reducing terminals, whose biocompatibility was excellent in the model used. AcG was described for the first time as a biopolymer that could have broad applications in the pharmaceutical and cosmetic industries, justifying the interest in further studies about AcG applications. use However investigated (AcG elemental rheological analyses Xray X ray XRD, XRD , (XRD) highPerformance high Performance HPLC, HPLC (HPLC) GPC, GPC (GPC) FTIR, FTIR (FTIR) UVVis UV Vis NMR. NMR . (NMR) Additionally erythrocytes βDGalactopyranose β D Galactopyranose 1→3. 13 1→3 1 3 (1→3) βGalactopyranose 1→6 16 6 (1→6 αLArabinofuranoside α L Arabinofuranoside 1→3,6 136 (1→3,6 nonreducing non reducing terminals industries (XRD (HPLC (GPC (FTIR (NMR 1→ (1→3 (1→ 1→3, (1→3, (1 (

https://doi.org/10.1590/0104-1428.20230025

Biological method of single-node cuttings for budburst in five fig cultivars subjected to artificial chilling singlenode single node
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Monteiro, Laís Naiara Honorato

; Leonel, Sarita Souza, Jackson Mirellys Azevedo Ribeiro, Luiza Rocha Martins, Rafaelly Calsavara Ferreira, Antonio Flavio Arruda Rodrigues, Maria Gabriela Fontanetti

Acta Scientiarum. Agronomy

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2024, Volume 46 elocation e62544

Resumo: En | Texto: En | PDF: En

ABSTRACT. Fig orchard expansion requires knowledge of the thermal requirements of genotypes available in different climatic regions. The budburst of fig cultivars was assessed by biological single-node cutting and exposure to artificial chilling. Cuttings from five cultivars were collected during two crop seasons, subsequently packaged in a horizontal position in a cold chamber (8 ± 0.5ºC), and artificially chilled for 0, 40, 80, 120, and 160h. Cuttings were preserved under controlled conditions (23 ± 1°C, RH 85%, and 16h photoperiod). The variables evaluated were the budding velocity, average time and final rate of sprouting, vigorous shoot rate, and average time to leaf opening. The single-node cutting test allowed the assessment of dormancy, which is influenced by the accumulation of chilling in each crop season. The average time and final budding rate varied depending on the temperature requirements for budding. The cultivars were classified on an increasing scale according to their chilling requirements as follows: Pingo de Mel < Roxo de Valinhos < Brown Turkey < White Genova < Troyano. The traditional cultivar in Brazil is Roxo de Valinhos, but all of the cultivars studied had the potential to diversify the fig orchards in this region. ABSTRACT regions singlenode single node seasons 8 ( 0.5ºC, 05ºC ºC 0.5ºC , 0 5ºC 0.5ºC) 40 80 120 160h h 23 (2 1C C 1 1°C 85 85% photoperiod. photoperiod . photoperiod) velocity sprouting opening dormancy season follows Troyano region 4 12 2

https://doi.org/10.4025/actasciagron.v46i1.62544

Novelties to the vascular Flora of the Ibitipoca Mountains, Minas Gerais, Brazil Mountains Gerais
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Toledo, Cássio A. P.

; Souza, Lukas R.

; Diniz, Adriana P.

; Santos, Adrielle J. M.

; Araujo, Carina de Graciano, Diego S. Arantes, Fabíula M. Sabino, Gabriel P. Guimarães, Gabriel S. Onorato, Geovana de C. Andrella, Giovani C. Waga, Isabela M. Castilho, Jade Silva, João P. S. Manoel, Laís B. Lima, Mariana C. A. Araújo, Michelly D. F. Feliz, Pablo Gaem, Paulo H. Luiz, Pedro L. Völtz, Rafael R. Gerace, Samuele Sawakuchi, Sonia Ivanauskas, Natália M. Koch, Ingrid Forzza, Rafaela C. Souza, Vinicius C. Rodrigues, Ricardo R.

Biota Neotropica

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2024, Volume 24 Nº 2 elocation e20231560

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract The Ibitipoca Mountains occur in southeastern Minas Gerais state, Southeast Brazil, and includes a mosaic of different vegetation types, as part of the Atlantic Forest domain. Such heterogeneity results in the occurrence of several ecotones in the region, considered essential buffer zones for maintaining biodiversity and structure among adjacent ecosystems. Given the importance of these environments for biodiversity conservation, floristic surveys are important to catalogue plant richness in natural areas, where species and landscapes have been destroyed, especially over the last decades. To contribute to increase the knowledge on the vascular Flora in the Ibitipoca Mountains, a floristic inventory was undertaken in private properties located in the boundaries of “Parque Estadual do Ibitipoca” (Ibitipoca State Park). Relevant findings of the present study include: characterization of the different vegetation types, 17 new records for the Flora of Minas Gerais, collection of 288 species never recorded in the state park (80% dissimilarity – especially due to the occurrence and size of different phytophysiognomies between these areas) and presence of 31 threatened species. In addition, discussions about conservation efforts and public policies are presented. Brazil types domain region ecosystems areas destroyed decades Parque Park. Park . Park) include 1 28 80% 80 (80 3 addition presented 2 8 (8 (

Resumo A Serra do Ibitipoca ocorre no sudeste do estado de Minas Gerais, sudeste do Brasil, e inclui um mosaico de diferentes tipos de vegetação, como parte do domínio da Mata Atlântica. Tal heterogeneidade é resultado da ocorrência de diversos ecótonos na região, considerados áreas de amortecimento essenciais para manutenção da biodiversidade e estrutura de ecossistemas adjacentes. Dada a importância destes ambientes para conservação da biodiversidade, inventários florísticos são importantes para catalogar a riqueza de plantas em áreas naturais, onde espécies e paisagens têm sido destruídas, especialmente nas últimas décadas. Para contribuir com o aumento do conhecimento sobre a Flora vascular na Serra do Ibitipoca, um inventário florístico foi conduzido em áreas privadas adjacentes ao Parque Estadual do Ibitipoca. As descobertas mais relevantes do presente estudo incluem: caracterização dos diferentes tipos de vegetação, 17 novos registros para a Flora de Minas Gerais, coleta de 288 espécies nunca registradas para o parque (80% de dissimilaridade – especialmente devido à ocorrência e tamanho de diferentes fitofisionomias entre as áreas) e presença de 31 espécies ameaçadas. Além disso, discussões sobre esforços para conservação e políticas públicas são apresentadas. Gerais Brasil vegetação Atlântica região naturais destruídas décadas incluem 1 28 80% 80 (80 3 ameaçadas disso apresentadas 2 8 (8 (

https://doi.org/10.1590/1676-0611-bn-2023-1560

The Effects of Single, Janus, and Triple Functionalization of Gold Nanoparticles on Physicochemical Properties and Cellular Uptake Single Janus
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Costa, Lais Helena M. da

; Fornasier, Franccesca

; Barros, Débora A. M. de

; Silva, Nilton P. da

; Costa, José M. J. da

; Verçoza, Brunno Renato F.

; Rodrigues, Juliany C F.

; Percebom, Ana Maria

Journal of the Brazilian Chemical Society

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2024, Volume 35 Nº 3 elocation e-20230137

Resumo: En | Texto: En | PDF: En

Combining direct targeting, enhanced cellular uptake, photothermal transduction capacity, and biocompatibility in the same system is a challenge to make the application of nanoparticles in biomedicine real. This study involves the functionalization of gold nanoparticles (AuNPs) in a few steps with strategic macromolecules to provide characteristics that are key to theragnostic agents. Polyethylene glycol (PEG) is hydrophilic and can improve nanoparticle stability and circulation lifetime. Polylactic acid (PLA) is a biodegradable hydrophobic polymer important to guarantee the interaction and uptake through the cellular membranes. Folate provides specific targeting because tumors usually overexpress folate receptor proteins. Single, double, and triple functionalization of spherical and rodlike AuNPs with these ligands provided different aggregation, stability, and plasmonic properties. Triple functionalization ensured simultaneous nanoparticle stability in an aqueous medium and enhanced cellular uptake. Infrared irradiation increased the temperature of gold nanorods more than of gold nanospheres due to the longitudinal surface plasmon resonance band. The results suggest that this functionalization strategy can be used to tune the desired properties for applications of gold nanoparticles, such as imaging and photothermal therapy in biomedicine research. capacity real (AuNPs agents PEG (PEG lifetime PLA (PLA membranes proteins Single double aggregation band research

https://doi.org/10.21577/0103-5053.20230137

Is the use of manual therapy in the craniomandibular and cervical regions beneficial for reducing orofacial pain and increasing mandibular mobility? Systematic review mobility
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Martins, Rita de Cassia das Neves

; Ferreira, Lais Silva

; Rosa, Nathalia Rodrigues de Mello

; Silva, Juliana Leite da

; Politti, Fabiano

; Biasotto-Gonzalez, Daniela Aparecida

BrJP

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2024, Volume 7 elocation e20240062

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT BACKGROUND AND OBJECTIVES: The use of manual therapy in the craniomandibular and cervical regions in the treatment of patients with temporomandibular disorders (TMD) has become common practice, and the literature supports the use of these techniques to relieve pain and improve the range of mandibular movement. Therefore, the organization of scientific findings can help clinicians make informed decisions. Thus, the objective of this systematic review was to evaluate the effectiveness of manual therapy in the craniomandibular region in patients with TMD and to compare it with manual therapy in the cervical region in terms of pain intensity and range of mandibular movement. CONTENTS: Following PRISMA guidelines, Randomized Clinical Trials were included with a population of adults of both genders with signs and symptoms of TMD. Case reports, pilot studies, case series, editorials, opinion letters, letters to the editor, literature reviews, cohort studies, and case-control studies were excluded. The search strategy was created using MESH and synonyms for TMD, cervical treatment, manual therapy, physiotherapy, exercise, pain, and mandibular range of motion. The databases Medline, Embase, Pubmed, Cochrane Library, Virtual Health Library, PEDro, Scielo, LILACS and Central were used. The Cochrane ROB2 risk of bias and the PEDro scale were used to assess the methodological quality of the included studies. Eight studies were eligible, published between 2013 and 2022, totaling 339 individuals with TMD aged between 18 and 65 years. The results of the present review showed that patients undergoing manual therapy in the craniomandibular and cervical regions, with or without the addition of exercises and/or patient education, present a progressive reduction in the intensity of orofacial pain and gains in mandibular range of motion. CONCLUSION: The results expand the data reported by other systematic reviews that investigated different aspects of the application of manual therapy in individuals with TMD. Manual therapy in the craniomandibular and cervical regions, whether associated with exercises and/or patient education, presents a clinically relevant improvement in the intensity of orofacial pain and mandibular range of motion. OBJECTIVES (TMD practice movement Therefore decisions Thus CONTENTS guidelines reports series editorials editor casecontrol control excluded physiotherapy exercise motion Medline Embase Pubmed Library Scielo ROB eligible 201 2022 33 1 6 years andor education CONCLUSION 20 202 3 2

RESUMO JUSTIFICATIVA E OBJETIVOS: O uso de terapia manual nas regiões craniomandibular e cervical no tratamento de pacientes com disfunção temporomandibular (DTM) tornou-se uma prática comum, sendo que a literatura apoia o uso dessas técnicas para alívio de dor e melhora da amplitude de movimento mandibular. Portanto, a organização dos achados científicos pode auxiliar o clínico na tomada de decisão. Assim sendo, o objetivo deste estudo foi avaliar a eficácia da terapia manual na região craniomandibular em pacientes com DTM e compará-la com a terapia manual na região cervical em desfechos de intensidade de dor e amplitude de movimento mandibular. CONTEÚDO: Seguindo as diretrizes do PRISMA, foram incluídos Ensaios Clínicos Randomizados com uma população de adultos, de ambos os sexos, com sinais e sintomas de DTM. Foram excluídos relatos de casos, estudos-piloto, séries de casos, editoriais, cartas de opinião, cartas ao editor, revisões de literatura, estudos de coorte e estudos de caso-controle. A estratégia de busca foi criada utilizando MESH e sinônimos para DTM, tratamento cervical, terapia manual, fisioterapia, exercício, dor e amplitude de movimento mandibular. Foram utilizadas as bases Medline, Embase, Pubmed, Cochrane Library, Biblioteca Virtual da Saúde, PEDro, Scielo, LILACS e Central. Foi utilizado o risco de viés da Cochrane ROB2 e a escala PEDro para avaliar a qualidade metodológica dos estudos incluídos. Oito estudos publicados entre 2013 e 2022 foram elegíveis, totalizando 339 indivíduos com DTM, com idade entre 18 e 65 anos. Os resultados da presente revisão mostraram que pacientes submetidos à terapia manual na região craniomandibular e região cervical, com ou sem adição de exercícios e/ou educação ao paciente, apresentaram redução progressiva na intensidade da dor orofacial e ganho na amplitude de movimento mandibular. CONCLUSÃO: Os resultados ampliam os dados reportados por outras revisões sistemáticas que investigaram diferentes aspectos da aplicação da terapia manual em indivíduos com DTM. A terapia manual na região craniomandibular e a terapia manual na região cervical, associada ou não a exercícios e/ou educação do paciente, contribui para uma melhora clínica em relação à intensidade da dor orofacial e amplitude de movimento mandibular. OBJETIVOS (DTM tornouse tornou se comum mandibular Portanto decisão comparála compará la CONTEÚDO PRISMA adultos sexos casos estudospiloto, estudospiloto piloto, piloto estudos-piloto editoriais opinião editor casocontrole. casocontrole caso controle. controle caso-controle fisioterapia exercício Medline Embase Pubmed Library Saúde Scielo Central ROB 201 202 elegíveis 33 1 6 anos eou paciente CONCLUSÃO 20 3 2

https://doi.org/10.5935/2595-0118.20240062-en

10.

Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer ChAdOx SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- arthritis SARS-CoV
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Cruz, Vitor Alves

; Guimarães, Camila Rêgo, Jozelia Machado, Ketty Lysie Libardi Lira Miyamoto, Samira Tatiyama Burian, Ana Paula Neves Dias, Laiza Hombre Pretti, Flavia Zon Batista, Danielle Cristina Filgueira Alves Mill, José Geraldo Oliveira, Yasmin Gurtler Pinheiro de Gadelha, Carolina Strauss Estevez Gouveia, Maria da Penha Gomes Moulin, Anna Carolina Simões Souza, Bárbara Oliveira Aguiar, Laura Gonçalves Rodrigues Vieira, Gabriel Smith Sobral Grillo, Luiza Lorenzoni Lima, Marina Deorce de Pasti, Laís Pizzol Surlo, Heitor Filipe Faé, Filipe Moulaz, Isac Ribeiro Macabú, Mariana de Oliveira Ribeiro, Priscila Dias Cardoso Magalhães, Vanessa de Oliveira Aguiar, Mariana Freitas de Biegelmeyer, Erika Peixoto;, Flávia Maria Matos Melo Campos Kayser, Cristiane Souza, Alexandre Wagner Silva de Castro, Charlles Heldan de Moura Ribeiro, Sandra Lúcia Euzébio Telles, Camila Maria Paiva França Bühring, Juliana Lima, Raquel Lima de Santos, Sérgio Henrique Oliveira Dos Dias, Samuel Elias Basualto Melo, Natália Seixas de Sanches, Rosely Holanda da Silva Boechat, Antonio Luiz Sartori, Natália Sarzi Hax, Vanessa Dória, Lucas Denardi Rezende, Rodrigo Poubel Vieira de Baptista, Katia Lino Fortes, Natália Rodrigues Querido Melo, Ana Karla Guedes de Melo, Tâmara Santos Vieira, Rejane Maria Rodrigues de Abreu Vieira, Adah Sophia Rodrigues Kakehasi, Adriana Maria Tavares, Anna Carolina Faria Moreira Gomes Landa, Aline Teixeira de Costa, Pollyana Vitoria Thomaz da Azevedo, Valderilio Feijó Martins-Filho, Olindo Assis Peruhype-Magalhães, Vanessa Pinheiro, Marcelo de Medeiros Monticielo, Odirlei André Reis-neto, Edgard Torres Dos Ferreira, Gilda Aparecida Souza, Viviane Angelina de Teixeira-Carvalho, Andréa Xavier, Ricardo Machado Sato, Emilia Inoue Valim, Valeria Pileggi, Gecilmara Salviato Silva, Nilzio Antonio da

Advances in Rheumatology

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2024, Volume 64 elocation 58

Resumo: En | Texto: En | PDF: En

Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26

https://doi.org/10.1186/s42358-024-00397-5

11.

Saving enamel: safe removal of residual residues after detaching orthodontic brackets enamel
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Almeida, Laís da Mata

; Jing, Jieni Zhang

; Rodrigues, Marcelo Souza

; Hilgert, Leandro Augusto

; Zanatta, Rayssa Ferreira

RGO - Revista Gaúcha de Odontologia

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2024, Volume 72 elocation e20240020

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT In conventional orthodontics, the adhesive fixation of brackets plays an essential role in the success of the treatment. However, the removal of these devices at the end of the treatment can pose risks of excessive wear to the external surface of the enamel, especially when rotary instruments are indiscriminately used to remove the resin composite employed in cementation. Given that enamel is an inorganic tissue with no regenerative capacity, it becomes imperative to adopt conservative techniques to minimize unnecessary wear. This text aimed to discuss more conservative approaches, exploring the use of multilayered burs instead of diamond tips, and associating them with polishing rubbers, magnification, and consideration of the fluorescence characteristics of adhesive materials. These practices are intended to minimize impact and preserve the integrity of the enamel. Reflecting on the indiscriminate use of diamond tips for enamel polishing emerges as essential in modern dental practice. orthodontics However cementation capacity approaches rubbers magnification materials practice

RESUMO Na ortodontia convencional, a fixação adesiva de braquetes desempenha um papel essencial no sucesso do tratamento. Entretanto, a remoção desses dispositivos ao final do tratamento pode acarretar riscos de desgaste excessivo da superficie externa do esmalte, especialmente quando instrumentos rotatórios são usados indiscriminadamente para remover o compósito resinoso empregado na cimentação. Dado que o esmalte um tecido inorgânico e sem capacidade de regeneração, torna-se imperativo adotar técnicas conservadoras para minimizar desgaste desnecessário. Este texto teve como propósito discutir abordagens mais conservadoras, explorando o uso de brocas multilaminadas em detrimento das pontas diamantadas, e associando-as a borrachas de polimento, magnificação, e consideração das características de fluorescência dos materiais adesivos. Essas práticas têm o intuito de minimizar o impacto e preservar a integridade do esmalte. A reflexão sobre a utilização indiscriminada de pontas diamantadas para polimento do esmalte emerge como essencial na prática odontológica moderna. convencional Entretanto cimentação regeneração tornase torna se desnecessário associandoas associando as magnificação adesivos moderna

https://doi.org/10.1590/1981-86372024002020240006

12.

Patient Blood Management Program Implementation: Comprehensive Recommendations and Practical Strategies Implementation
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Céspedes, Isabel Cristina

; Figueiredo, Maria Stella Hossne Junior, Nelson Americo Suriano, Ítalo Capraro Rodrigues, Rita de Cássia Barros, Melca Maria Oliveira Paiva Neto, Manoel Antonio de Atallah, Fernanda Chohfi Benini, Bárbara Burza Gonzalez, Adriano Miziara Sparapani, Fábio Veiga de Castro Barros Júnior, Newton de Carneiro, Ieda Aparecida Sarto, Celina Mayumi Morita Motoyama, Caio Sussumu de Macedo Sacchi, Leonardo Piovezan, Victor Almeida, Simone Luna de Pereira-Rufino, Laís da Silva Guizilini, Solange Rocco, Isadora Salvador Mansur, Nacime Salomão Arakaki, Jaquelina Sonoe Ota Santos, Antonio Alceu dos Panfilio, Carlos Eduardo

Brazilian Journal of Cardiovascular Surgery

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2024, Volume 39 Nº 5 elocation e20240205

Resumo: En | Texto: En | PDF: En

ABSTRACT Introduction: Blood transfusion is one of the most common medical practices worldwide. However, current scientific literature has shown that the immunomodulatory effects of blood transfusion are associated with an increased likelihood of infection, prolonged hospitalization, and morbimortality. Also, it means high costs for healthcare systems. Methods: In this context, acknowledging that blood transfusions are essentially heterologous cell transplantations, the use of therapeutic options has gained strength and is collectively known as the patient blood management (PBM) program. PBM is an approach based on three main pillars: (1) treating anemias and coagulopathies in an optimized manner, especially in the preoperative period; (2) optimizing perioperative hemostasis and the use of blood recovery systems to avoid the loss of the patient's blood; (3) anemia tolerance, with improved oxygen delivery and reduced oxygen demand, particularly in the postoperative period. Results: Current scientific evidence supports the effectiveness of PBM by reducing the need for blood transfusions, decreasing associated complications, and promoting more efficient and safer blood management. Thus, PBM not only improves clinical outcomes for patients but also contributes to the economic sustainability of healthcare systems. Conclusion: The aim of this review was to summarize PBM strategies in a comprehensive, evidence-based approach through a systematic and structured model for PBM implementation in tertiary hospitals. The recommendations proposed herein are from researchers and experts of a high-complexity university hospital in the network of the Sistema Único de Saúde, presenting itself as a strategy that can be followed as a guideline for PBM implementation in other settings. Introduction worldwide However infection hospitalization morbimortality Also Methods context transplantations (PBM program pillars 1 (1 manner period 2 (2 s 3 (3 tolerance demand Results complications Thus Conclusion comprehensive evidencebased hospitals highcomplexity complexity Saúde settings (

https://doi.org/10.21470/1678-9741-2024-0205

13.

Condição de saúde infanto-juvenil em comunidades ribeirinhas na Amazônia brasileira: estudo transversal infantojuvenil infanto juvenil brasileira
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Mendes, Vanessa Alves

; Araújo, Laís Xavier

; Pereira, Priscilla Perez da Silva

; Freitas, Jeanne Lúcia Gadelha de

; Carvalho, Dario Pires de

; Bastos, Wanderley Rodrigues

Cadernos Saúde Coletiva

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2024, Volume 32 Nº 1 elocation e32010234

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background: Social determinants interfere in the health-disease process of the riverside population, associated with territorial isolation and restricted access to health goods and services. Objective: The objective of this study was to identify factors associated with the health conditions of children and adolescents and their mothers, from two riverside communities on the Madeira River, Amazonas, Brazil. Method: A cross-sectional study was carried out in April and August 2017 in two riverside communities in the Amazon, with mothers, children, and adolescents up to 19 years old. Sociodemographic conditions and maternal and health characteristics of children and adolescents were evaluated. Poisson regression analysis was performed using Stata 13. Results: Of the 94 participating mothers, 56.4% declared their children’s health conditions as fair to bad. The regular and poor health condition of children and adolescents was associated with the place of residence, number of appliances, daily consumption of snacks, sweets, and artificial juice, having a chronic disease, and having a history of hospitalization once in a lifetime (p<0.05). In the adjusted model, only hospitalization had a statistically significant association (PR=1.60; 1.13–2.26) with regular and poor health. Conclusion: Children and adolescents in the evaluated communities are vulnerable to illness due to precarious socioeconomic factors, sanitary conditions, and low access to health services. Background healthdisease disease population services Objective mothers River Amazonas Brazil Method crosssectional cross sectional 201 Amazon 1 old 13 Results 9 564 56 4 56.4 childrens s bad residence appliances snacks sweets juice p<0.05. p005 p p<0.05 . 0 05 (p<0.05) model PR=1.60 PR160 PR 60 (PR=1.60 1.13–2.26 113226 2 26 Conclusion 20 5 56. p00 p<0.0 (p<0.05 PR=1.6 PR16 6 (PR=1.6 1.13–2.2 11322 p0 p<0. (p<0.0 PR=1. PR1 (PR=1. 1.13–2. 1132 p<0 (p<0. PR=1 (PR=1 1.13–2 113 p< (p<0 PR= (PR= 1.13– 11 (p< (PR 1.13 (p 1.1 1.

Resumo Introdução: Os determinantes sociais interferem no processo saúde-doença de população ribeirinha, associados ao isolamento territorial, acesso restrito de bens e serviços de saúde. Objetivo: Identificar fatores associados às condições de saúde de crianças e adolescentes e suas mães, de duas comunidades ribeirinhas no rio Madeira, Amazonas, Brasil. Método: Estudo transversal, realizado em abril e agosto de 2017 em duas comunidades ribeirinhas amazônica, com mães, crianças e adolescentes até 19 anos. Foi avaliada as condições sociodemográficas, características maternas, de saúde, das crianças e adolescentes. Foi realizada análise de regressão de Poisson por meio do Stata 13. Resultados: Das 94 mães participantes, 56,4% declararam condições de saúde de seus filhos como regulares a ruins. A condição regular e ruim de saúde de crianças e adolescentes foi associada ao local de moradia, número de eletrodomésticos, consumo diário de salgadinhos, doces e suco artificial, ter doença crônica e ter histórico de internação hospitalar uma vez na vida (p<0,05). No modelo ajustado, apenas a internação hospitalar teve associação estatisticamente significativa (PR=1.60; 1,13–2,26) com a condição regular e ruim em saúde. Conclusão: As crianças e adolescentes das comunidades avaliadas são vulneráveis ao adoecimento pelas precárias condições socioeconômicas, sanitárias e baixo acesso aos serviços de saúde. Introdução saúdedoença ribeirinha territorial Objetivo Madeira Amazonas Brasil Método transversal 201 amazônica 1 anos sociodemográficas maternas 13 Resultados 9 participantes 564 56 4 56,4 ruins moradia eletrodomésticos salgadinhos artificial p<0,05. p005 p p<0,05 . 0 05 (p<0,05) ajustado PR=1.60 PR160 PR 60 (PR=1.60 1,13–2,26 113226 2 26 Conclusão socioeconômicas 20 5 56, p00 p<0,0 (p<0,05 PR=1.6 PR16 6 (PR=1.6 1,13–2,2 11322 p0 p<0, (p<0,0 PR=1. PR1 (PR=1. 1,13–2, 1132 p<0 (p<0, PR=1 (PR=1 1,13–2 113 p< (p<0 PR= (PR= 1,13– 11 (p< (PR 1,13 (p 1,1 1,

https://doi.org/10.1590/1414-462x202432010234

14.

Future-ready crops, genetic variability in lima bean seeds Futureready Future ready crops
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Souza, Jardel da Silva

; Rodrigues, Lais Nóbrega Ferreira, Lais Thomaz Unêda-Trevisoli, Sandra Helena Nascimento, Naysa Flávia Ferreira do

Acta Scientiarum. Agronomy

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2024, Volume 46 elocation e66767

Resumo: En | Texto: En | PDF: En

ABSTRACT. Lima bean cultivation has not received proper national and regional attention by research agencies, impairing the knowledge of the agronomic characteristics and its potential, information that is essential for the selection and launching of superior genotypes. The objective of this work was to characterize the seeds of 17 lima bean genotypes produced by family farmers in Paraíba State. The characterization was based on the descriptors for Phaseolus lunatus. A completely randomized design was used with 15 replicates. Data were submitted to analysis of variance with a subsequent grouping of means by the Scott-Knott test at 1% of probability. For analysis of the genetic diversity, the Tocher method was used based on the generalized Mahalanobis distance. There is variability among the genotypes. According to the means test, genotype 10 has a higher seed length, width, and weight. Considering the diversity among the groups and aiming to select light-colored and higher means of the evaluated traits, the selection of genotypes 8, 13, 4, and 10 is recommended to establish a breeding program that satisfies both the consumer and the producer. ABSTRACT agencies potential 1 State lunatus replicates ScottKnott Scott Knott probability distance length width weight lightcolored light colored traits 8 13 4 producer

https://doi.org/10.4025/actasciagron.v46i1.66767

15.

VIDEOFLUOROSCOPIC EVALUATION OF THE IMPACT OF CAPSULE SIZE AND SUBJECT’S AGE AND GENDER ON CAPSULE SWALLOWING SUBJECTS SUBJECT S
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GUTIERRES, Laís Flavia de Souza

; MONTALDI, Marina Rodrigues

; NASCIMENTO, Weslania Viviane

; DANTAS, Roberto Oliveira

Arquivos de Gastroenterologia

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2024, Volume 61 elocation e23092

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Background: People recurrently have difficulties swallowing solid medications, which can be associated with the size of the medication and the age and gender of individuals. Objective: To evaluate the impact of capsule size and adults’ age and gender on oral and pharyngeal capsule transit during capsule swallows. Methods: Videofluoroscopy was used to measure capsule oral and pharyngeal transit during swallows in 49 healthy individuals (17 men and 32 women), with a mean age of 46 years (ranging from 23 to 88 years). Smaller capsules were filled with 0.50 mL of barium sulfate, and larger capsules were filled with 0.95 mL of barium sulfate; the volume of liquid ingested with the capsules was also quantified in each ingestion. The measurements included the oral preparation time, oral transit time, swallowing reaction time, time to laryngeal vestibule closure, laryngeal vestibule closure duration, pharyngeal transit time, and upper esophageal sphincter opening duration. Results: The capsule size did not influence either the oral or pharyngeal transit time. Increased liquid volume was ingested with larger capsules and by people older than 40 years. The oral transit time was shorter in older adults (60-88 years), and the time to laryngeal vestibule closure was longer in women. Conclusion: The size of large capsules did not make a difference in oral or pharyngeal transit when compared with smaller capsules. The capsule size and the participant’s age influenced the volume of liquid ingested - larger capsules and older individuals required a larger volume. The capsule oral transit was faster in individuals older than 60 years. Background medications Objective Methods 4 17 (1 3 women, women , women) ranging 2 8 . years) 050 0 50 0.5 sulfate 095 95 0.9 ingestion duration Results 6088 (60-8 years, Conclusion participants participant s 6 1 ( 05 5 0. 09 9 608 (60- (60 (6

RESUMO Contexto: Algumas pessoas apresentam recorrentemente dificuldades para engolir medicamentos sólidos, o que pode estar associado ao tamanho do medicamento, à idade e ao gênero dos indivíduos. Objetivo: Avaliar, em adultos, o impacto do tamanho da cápsula, da idade e do gênero no trânsito oral e faríngeo de cápsulas. Métodos: Videofluoroscopia foi utilizada para medir o trânsito oral e faríngeo de cápsulas em 49 indivíduos saudáveis (17 homens e 32 mulheres), com idade média de 46 anos (limites de 23 e 88 anos). Cápsulas menores foram preenchidas com 0,50 mL e cápsulas maiores foram preenchidas com 0,95 mL de sulfato de bário; o volume de líquido ingerido com as cápsulas foi quantificado em cada ingestão. Foram medidos o tempo de preparo oral, tempo de trânsito oral, tempo de reação da deglutição, tempo para fechamento do vestíbulo laríngeo, tempo de fechamento do vestíbulo laríngeo, tempo de trânsito faríngeo e tempo de abertura do esfíncter superior do esôfago. Resultados: O tamanho da cápsula não influenciou o tempo de trânsito oral ou faríngeo. Mais líquido foi ingerido com cápsulas maiores e por pessoas com mais de 40 anos. O tempo de trânsito oral foi menor em idosos (60-88 anos) e o tempo de fechamento do vestíbulo laríngeo foi maior em mulheres. Conclusão: O tamanho da cápsula não influenciou o trânsito oral e faríngeo, porém houve maior volume de líquido ingerido com a cápsula maior e nos mais idosos. O trânsito oral da cápsula foi mais rápido em indivíduos com mais de 60 anos. Contexto sólidos medicamento Objetivo Avaliar adultos Métodos 4 17 (1 3 mulheres, mulheres , mulheres) limites 2 8 . 050 0 50 0,5 095 95 0,9 bário ingestão deglutição esôfago Resultados 6088 (60-8 Conclusão 6 1 ( 05 5 0, 09 9 608 (60- (60 (6

https://doi.org/10.1590/s0004-2803.246102023-92

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Glossário e ajuda para busca

Você pode enriquecer sua busca de uma forma muito simples. Use os índices de pesquisa combinados com os conectores (AND ou OR) e especifique cada vez mais sua busca.

Por exemplo, se você deseja buscar artigos sobre
casos de dengue no Brasil em 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

Veja abaixo a lista completa de índices de pesquisa que podem ser usados:

Cód. do Índice	Elemento
ti	título do artigo
au	autor
kw	palavras-chave do artigo
subject	assunto (palavras do título, resumo e palavras-chave)
ab	resumo
ta	título abreviado da revista (ex. Cad. Saúde Pública)
journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

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Email: scielo@scielo.org

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