Abstract The NBR 7190-3 (ABNT, 2022) presents various methods to determine the wood's modulus of elasticity, allowing for the adoption of equivalence between the modulus of elasticity in compression (Ec0) and tension (Et0). However, it does not provide a way to estimate the modulus of elasticity in bending (EM0), and such estimates do not consider the variation in anatomical structures among species. Faced with this gap, it is necessary to evaluate whether these equations are valid for different species. This article evaluated the elastic properties of three species: Cumaru (Dipteryx odorata), Marupá (Simarouba amara Aubl., Simaroubaceae) and Roxinho (Peltogyne spp., Leguminosae). For this purpose, a non-destructive flexural test was initially conducted, followed by compression and tension tests. Microscopic images were compared to understand the influence of anatomical structures on stiffness properties. The results confirmed the equivalence between Ec0 and Et0. The higher concentration of parenchyma cells in Cumaru and Roxinho is responsible for statistically lower values of EM0 compared to Ec0 and Et0. 71903 7190 3 7190- ABNT, ABNT (ABNT 2022 woods wood s Ec (Ec0 Et0 Et . (Et0) However EM0, EM , (EM0) species gap Dipteryx odorata, odorata odorata) Simarouba Aubl Aubl. Simaroubaceae Peltogyne spp spp. Leguminosae. Leguminosae Leguminosae) purpose nondestructive non destructive conducted tests 719 202 (Ec (Et0 (EM0 71 20 (Et (EM 7 2

Resumo A NBR 7190-3 (ABNT, 2022) apresenta diferentes métodos para determinar o módulo de elasticidade da madeira, permitindo a adoção de equivalência entre o módulo de elasticidade na compressão (Ec0) e na tração (Et0). Por outro lado, não apresenta uma forma de estimar o módulo de elasticidade na flexão (EM0), e tais estimativas não consideram a variação das estruturas anatômicas das espécies. Diante dessa lacuna, é necessário avaliar se essas equações são válidas para diferentes espécies. O presente artigo avaliou as propriedades elásticas de três espécies: Cumaru (Dipteryxodorata), Marupá (Simarouba amara Aubl., Simaroubaceae) e Roxinho (Peltogyne spp., Leguminosa). Para isso, realizou-se o ensaio não destrutivo de flexão, seguido de ensaios à compressão e à tração. Imagens microscópicas foram comparadas, para compreender a influência das estruturas anatômicas nas propriedades de rigidez. Os resultados confirmaram a equivalência entre Ec0 e Et0. A maior concentração de parênquimas no Cumaru e no Roxinho é responsável pelos valores estatisticamente inferiores de EM0 em relação ao Ec0 e Et0. 71903 7190 3 7190- ABNT, ABNT (ABNT 2022 madeira Ec (Ec0 Et0 Et . (Et0) lado EM0, EM , (EM0) espécies lacuna Dipteryxodorata, Dipteryxodorata (Dipteryxodorata) Simarouba Aubl Aubl. Simaroubaceae Peltogyne spp spp. Leguminosa. Leguminosa Leguminosa) isso realizouse realizou comparadas rigidez 719 202 (Ec (Et0 (EM0 (Dipteryxodorata 71 20 (Et (EM 7 2

Objective: To investigate whether having a higher number of depressive symptoms is associated with negative self-rated health (SRH) even in the absence of illness. Methods: This is a secondary analysis of baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil), conducted in 2015-2016, using a national sample of 9,412 people aged 50 or over. SRH was dichotomized into poor or very poor and very good or excellent, good, or average. Depressive symptoms were assessed through the eight-item Center for Epidemiologic Studies Depression Scale (CES-D8). Sociodemographic variables, information about unhealthy behaviors, and the number of chronic conditions were also analyzed. Results: Having depressive symptoms was strongly associated with poor or very poor SRH both in the unadjusted and adjusted analyses. The magnitude of the association was reduced when the number of chronic illnesses was included in the multivariate analysis, along with the other sociodemographic variables and unhealthy behaviors (OR 1.35, 95%CI 1.31-1.39). Conclusion: Having depressive symptoms may contribute towards having a poorer perception of health, even in the absence of health conditions. SRH is a multidimensional construct that can accurately reflect a person’s state of general mental health. Objective selfrated self rated (SRH illness Methods ELSIBrazil, ELSIBrazil ELSI Brazil , (ELSI-Brazil) 20152016, 20152016 2015 2016, 2016 2015-2016 9412 9 412 9,41 5 over excellent average eightitem eight item CESD8. CESD8 CESD CES D8 . D (CES-D8) analyzed Results analyses OR 135 1 35 1.35 95CI CI 95 1.311.39. 131139 1.31 1.39 31 39 1.31-1.39) Conclusion persons person s (ELSI-Brazil 2015201 201 2015-201 941 41 9,4 (CES-D8 13 3 1.3 311 1.311.39 13113 131 139 1.31-1.39 201520 20 2015-20 94 4 9, (CES-D 1. 1.311.3 1311 1.31-1.3 20152 2 2015-2 1.311. 1.31-1. 2015- 1.311 1.31-1 1.31-

Abstract Composite steel decking concrete slabs are an important structural member in building construction. Research on its thermal behavior should be developed to understand its fire performance. In this paper, a comparison of the temperature distribution in the cross-section of steel decking concrete slabs subjected to fire is made through three different procedures: (a) standardized analytical, (b) experimental and (c) numerical. The analytical method was the one proposed in NBR 14323 standard. The experimental tests corresponding to eight real-scale fire tests on composite slabs carried out by the authors. The numerical tests were done for the same configurations of the experimental tests and used the FEA software Abaqus. Steel decking temperatures obtained with NBR 14323 methodologies showed good convergence with the experimental and numerical ones. The same was not observed for the concrete, positive and negative rebar. construction performance paper crosssection cross section procedures (a b (b c (c 1432 standard realscale real scale authors Abaqus ones rebar 143 14 1

Resumo As lajes mistas de aço e concreto (steel deck) trata-se de um importante elemento construtivo de edifícios estruturados. Pesquisas sobre o seu comportamento em altas temperaturas devem ser conduzidas para compreender o seu desempenho ao incêndio. Neste estudo, comparou-se a distribuição de temperatura na seção transversal (isotermas) destas lajes através de três procedimentos: (a) analítico, (b) experimental e (c) numérico. O procedimento analítico é o proposto pela norma NBR 14323. Os testes experimentais correspondem a oito protótipos de lajes ensaiados em escala real pelos autores. A parte numérica foi feita com a mesma configuração da experimental usando o método dos elementos finitos com o software Abaqus. No caso das temperaturas médias da chapa do deck metálico, notou-se convergência entre as obtidas pelo procedimento analítico da NBR 14323 e os resultados experimentais e numéricos. O mesmo não ocorreu para as isotermas do concreto, bem como armaduras positivas e negativas. steel tratase trata se estruturados incêndio estudo comparouse comparou (isotermas procedimentos (a b (b c (c numérico autores Abaqus metálico notouse notou 1432 numéricos negativas 143 14 1

Abstract The Neotropics are one of the most biodiverse regions of the world, where environmental dynamics, climate and geology resulted in a complex diversity of fauna and flora. In such complex and heterogeneous environments, widely distributed species require deep investigation about their biogeographic history. The gray-breasted sabrewing hummingbird Campylopterus largipennis is a species complex that occurs in forest and open ecosystems of South America, including also high-altitude grasslands. It has been recently split into four distinct species distributed in Amazonia (rainforest) and Cerrado (savanna) biomes with boundaries marked by ecological barriers. Here, we investigated the evolutionary dynamics of population lineages within this neotropical taxon to elucidate its biogeographical history and current lineage diversity. We used a reduced-representation sequencing approach to perform fine-scale population genomic analyses of samples distributed throughout Amazonia and Cerrado localities, representing all four recently recognized species. We found a deep genetic structure separating species from both biomes, and a more recent divergence between species within each biome and from distinct habitats. The population dynamics through time was shown to be concordant with known vicariant events, isolation by distance, and altitudinal breaks, where the Amazon River and the Espinhaço Mountain Range worked as important barriers associated to speciation. world flora environments graybreasted gray breasted America highaltitude high altitude grasslands rainforest (rainforest savanna (savanna Here reducedrepresentation reduced representation finescale fine scale localities habitats events distance breaks speciation

ABSTRACT Objective: To assess mothers’ knowledge on sun exposure related to serum vitamin D levels in the neonatal period. Methods: Observational, analytical and cross-sectional study, carried out from August 2020 to May 2021 through a questionnaire directed to mothers of newborns, in a maternity hospital in Southern Brazil. Results: From 141 interviewees, 132 (93.6%) believe it is important to expose the neonate to sun, 101 (71.6%) think this exposure can increase vitamin D levels, 86 (61%) received such information from a doctor, 108 (76.6%) believe there are no risks of sun exposure, 88 (62.4%) claim it isn´t necessary to use any kind of protection, 96 (68.1%) said that only exposure to the sun was necessary to maintain adequate levels of vitamin D during the neonatal period. Only two mothers (1.4%) claim that you should not exposure the neonate to the sun, and only one (0.7%) stated that sun expose can cause skin problems. Conclusions: Most mothers lack satisfactory knowledge about sun exposure related to serum vitamin D levels in the neonatal period. The need to inform and clarify the population about sun exposure during this period is remarkable, in addition to disseminating the proper way to maintain serum levels of vitamin D. Objective Methods Observational crosssectional cross sectional study 202 newborns Brazil Results 14 interviewees 13 93.6% 936 93 6 (93.6% 10 71.6% 716 71 (71.6% 8 61% 61 (61% doctor 76.6% 766 76 (76.6% 62.4% 624 62 4 (62.4% isnt isn t protection 9 68.1% 681 68 1 (68.1% 1.4% (1.4% 0.7% 07 0 7 (0.7% problems Conclusions remarkable 20 93.6 (93.6 71.6 (71.6 (61 76.6 (76.6 62.4 (62.4 68.1 (68.1 1.4 (1.4 0.7 (0.7 2 93. (93. 71. (71. (6 76. (76. 62. (62. 68. (68. 1. (1. 0. (0. (93 (71 ( (76 (62 (68 (1 (0 (9 (7

RESUMO Objetivo: Avaliar o conhecimento das mães acerca da exposição solar relacionada com níveis séricos de vitamina D no período neonatal. Métodos: Estudo observacional, analítico e transversal, realizado de agosto de 2020 a maio de 2021 por meio de questionário dirigido às mães de recém-nascidos, em uma maternidade no sul do Brasil. Resultados: De 141 entrevistadas, 132 (93,6%) acreditam ser importante expor o lactente ao sol no primeiro mês de vida, 101 (71,6%) acham que essa exposição aumenta os níveis de vitamina D, 86 (61,0%) receberam tal informação de um médico, 108 (76,6%) acreditam que expor o neonato ao sol não causa riscos para a saúde, 88 (62,4%) acham que não é necessário usar proteção contra radiação solar ao expor o neonato ao sol, e 96 (68,1%) afirmaram que apenas a exposição ao sol basta para manter os níveis adequados de vitamina D durante o período neonatal. Apenas duas mães (1,4%) afirmaram que não se deve expor o neonato ao sol e uma (0,7%) que a exposição solar pode causar problemas de pele. Conclusões: A maioria das mães não possui conhecimento satisfatório acerca da exposição solar relacionada aos níveis séricos de vitamina D no período neonatal. É notável a necessidade de informar e esclarecer a população sobre a exposição solar nesse período, além de disseminar a maneira adequada de manter os níveis séricos de vitamina D. Objetivo neonatal Métodos observacional transversal 202 recémnascidos, recémnascidos recém nascidos, nascidos recém-nascidos Brasil Resultados 14 entrevistadas 13 93,6% 936 93 6 (93,6% vida 10 71,6% 716 71 (71,6% 8 61,0% 610 61 0 (61,0% médico 76,6% 766 76 (76,6% saúde 62,4% 624 62 4 (62,4% 9 68,1% 681 68 1 (68,1% 1,4% (1,4% 0,7% 07 7 (0,7% pele Conclusões 20 93,6 (93,6 71,6 (71,6 61,0 (61,0 76,6 (76,6 62,4 (62,4 68,1 (68,1 1,4 (1,4 0,7 (0,7 2 93, (93, 71, (71, 61, (61, 76, (76, 62, (62, 68, (68, 1, (1, 0, (0, (93 (71 (61 (76 (62 (68 (1 (0 (9 (7 (6 (

Abstract The geographical mesoregion of the Triângulo Mineiro and Alto Paranaíba has an economy strongly focused on agribusiness, with grain and sugarcane production levels that put them at the forefront of the economic and political scenario of the state of Minas Gerais, Brazil. However, scientific production focused on soil diversity in this region has long been undervalued compared to other regions of the state and country where the soils exhibit more diverse and, therefore, more intriguing geological and geomorphological characteristics. This paper aims to evaluate the evolution and spatialization of bibliographic production with the central theme of soils in the Triângulo Mineiro and Alto Paranaíba mesoregion. As such, papers from the last three decades within the municipalities of the studied region were selected from five important journals. The papers from the initial screening were analyzed for the following: the profile of the authors (gender and institutional affiliation); number of authors per paper; methods used; and distribution of these papers across the selected region. The results indicate a concentration of papers in four municipalities and a total lack of publications from another 40. Males heavily dominated scientific production in the analyzed segments. Despite the mesoregion having 11 public higher education institutions, most municipalities' soil research was incipient. Regarding the methods used by researchers, in municipalities where more institutional partnerships were made possible, there was an increase in the number of techniques and methods explored in investigating problems. Although the study area presents relative geological and geomorphological homogeneity that gives a monotonous aspect to the landscape, knowledge of its pedodiversity, and its economic significance for agriculture, justifies the need to resume soil studies in the Triângulo Mineiro and Alto Paranaíba, particularly by exploring methods and municipalities that are still little known. agribusiness Gerais Brazil However therefore characteristics such journals following gender affiliation affiliation) 40 segments 1 institutions incipient researchers possible problems landscape pedodiversity agriculture known 4

Resumo A mesorregião geográfica do Triângulo Mineiro e Alto Paranaíba possui economia fortemente voltada ao agronegócio, com níveis de produção de grãos e cana-de-açúcar que a colocam em posição de destaque no cenário político e econômico de Minas Gerais. Todavia, a produção científica voltada à diversidade de solos desta região foi subvalorizada em detrimento de outras regiões do Estado e do País, onde os solos apresentam características geológicas e geomorfológicas mais diversas e então mais intrigantes. O objetivo deste trabalho é avaliar a evolução e espacialização da produção bibliográfica com a temática central de solos na mesorregião do Triângulo Mineiro e Alto Paranaíba. Para isso, foram selecionados artigos das três últimas décadas, de cinco importantes revistas, que tinham como tema central o solo dentro dos munícipios pertencentes a região estudada. A partir dessa primeira triagem estes artigos foram analisados levando em conta: perfil dos autores (gênero e instituição pertencente); quantidade de autores por artigo; métodos utilizados; e distribuição destes artigos pela região selecionada. Os resultados apontam que há uma concentração de artigos em quatro municípios e um vazio em outros 40. A produção científica nos recortes analisados se mostrou fortemente dominada pelo sexo masculino. Apesar da mesorregião possuir 11 instituições públicas de ensino superior, a pesquisa sobre solos se mostrou incipiente na maioria dos municípios. Em relação aos métodos utilizados pelos pesquisadores, municípios onde mais parcerias institucionais foram viabilizadas, houve simultaneamente um aumento no número de técnicas e métodos explorados nas investigações das problemáticas. Mesmo com a área de estudo apresentando uma relativa homogeneidade geológica e geomorfológica que confere aparente monotonia à paisagem, conhecer sua pedodiversidade, assim como a importância econômica para a agricultura, justificam a necessidade de uma retomada nos estudos de solos para o Triângulo Mineiro e Alto Paranaíba, principalmente explorando métodos e municípios ainda pouco conhecidos. agronegócio canadeaçúcar cana açúcar Gerais Todavia País intrigantes isso décadas revistas estudada conta gênero pertencente pertencente) artigo selecionada 40 masculino 1 superior pesquisadores viabilizadas problemáticas paisagem pedodiversidade agricultura conhecidos 4

Abstract Since the inception of COVID-19 pandemic, there has been a challenging race for the development of precise diagnostic tests. Specific SARS-CoV-2 serological assays are the main tools used to estimate the rate of past infections or herd immunity in epidemiological studies, in addition to being helpful in guiding public health management policies. In this study, an in-house ELISA based on the construct of SARS-CoV-2 nucleocapsid (N) proteins, named rCoV2, rCoV4, and rCoV7, showed diagnostic performance for the detection of IgG antibodies. Sensitivity was evaluated in serum samples from patients with mild to moderate or severe COVID-19 infections, which were collected at different time points, while specificity was evaluated using pre-pandemic sera. In samples from mild to moderate cases obtained ≥16 days after the onset of symptoms, the sensitivities for rCoV2, rCoV4, and rCoV7 were 66.7%, 75%, and 77.8%, respectively. For samples from severe cases, the sensitivity was above 80% for all constructs. All proteins showed high specificity (94-98%). Overall, rCoV7 (C-terminus N-protein portion) showed better diagnostic performance, with 62.3% sensitivity in moderate and severe cases and 96.6% specificity. The SARS-CoV-2 ELISA using N-protein-based constructs could be a promisor tool for investigate the epidemiology of COVID-19 and monitor population-level serosurveillance. COVID19 COVID 19 COVID-1 pandemic tests SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- studies policies study inhouse house N (N rCoV2 rCoV rCoV4 antibodies points prepandemic pre sera 16 ≥1 symptoms 667 66 7 66.7% 75 75% 778 77 8 77.8% respectively 80 9498%. 9498 94 98% . 98 (94-98%) Overall Cterminus C terminus Nprotein protein portion 623 62 3 62.3 966 96 6 96.6 Nproteinbased populationlevel population level serosurveillance COVID1 1 COVID- SARS-CoV ≥ 66.7 77.8 9498% 949 9 (94-98% 62. 96. 66. 77. (94-98 (94-9 (94- (94 (9 (

ABSTRACT Fresh corn is a highly appreciated vegetable in Brazil; this crop has high added value and profitability when compared to dry corn. Despite the consumer market demand for quality, cultivars are not launched every crop season and there is a small number of cultivars available to growers. This denotes a need for breeding programs focused on generating information and genotypes that can occupy this market niche. The objective of this work was to evaluate the progress of five cycles of intrapopulation recurrent selection in half-sib progenies of fresh corn, in the southwest region of Goiás. A randomized block experimental design was used, with evaluation of 64 progenies of corn half-sib progenies and selection intensity of 30% per cycle, with three replications, in the 2011-2012, 2013-2014, 2015-2016, 2017-2018, and 2020-2021 summer crop seasons. The half-sib progenies of fresh corn exhibited genetic variability through intrapopulation recurrent selection in the different selection cycles, which is still promising for further selections after five cycles, with evaluation of 64 progenies per cycle. The base population from crossings between hybrids for tropical and temperate climates showed to be promising for increasing the genetic base of fresh corn populations, with satisfactory gains over the five cycles, presenting mean heritability between the cycles of approximately 78.9% for relative chlorophyll index, 62.2% for plant height, 75.1% for ear insertion height, 70% for ear diameter, 56.6% for ear length, 71.4% for unhusked ear yield, and 71% for marketable ear yield. Brazil quality growers niche halfsib half sib Goiás used 6 30 cycle replications 20112012, 20112012 2011 2012, 2012 2011-2012 20132014, 20132014 2013 2014, 2014 2013-2014 20152016, 20152016 2015 2016, 2016 2015-2016 20172018, 20172018 2017 2018, 2018 2017-2018 20202021 2020 2021 2020-202 seasons populations 789 78 9 78.9 index 622 62 2 62.2 height 751 75 1 75.1 70 diameter 566 56 56.6 length 714 71 4 71.4 yield 3 2011201 201 2011-201 2013201 2013-201 2015201 2015-201 2017201 2017-201 2020202 202 2020-20 7 78. 62. 75. 5 56. 71. 201120 20 2011-20 201320 2013-20 201520 2015-20 201720 2017-20 202020 2020-2 20112 2011-2 20132 2013-2 20152 2015-2 20172 2017-2 20202 2020- 2011- 2013- 2015- 2017-

RESUMO O milho fresco é uma hortaliça muito apreciada pelos brasileiros e, além disso, possui alto valor agregado e maior lucratividade, quando comparado aos grãos secos. O mercado consumidor apesar de exigente na qualidade, não é abastecido com novas cultivares a cada safra e com um número ínfimo sendo disponível aos produtores. Assim, existe a necessidade da criação de programas de melhoramento, com o intuito de gerar informações e genótipos capazes de suprir esse nicho de mercado. O objetivo do estudo foi avaliar o progresso da seleção em progênies de meiosirmãos de milho fresco, em cinco ciclos de seleção recorrente intrapopulacional, na região sudoeste de Goiás. O delineamento experimental utilizado foi o de blocos casualizados, com a avaliação de 64 progênies de meios-irmãos e intensidade de seleção de 30% por ciclo, com três repetições, em diferentes safras de verão (2011-2012, 2013-2014, 2015-2016, 2017-2018 e 2020-2021). As progênies de famílias de meios-irmãos de milho fresco apresentaram variabilidade genética por meio de seleção recorrente intrapopulacional nos diferentes ciclos de seleção, com avaliação de 64 progênies por ciclo. A população base de cruzamentos entre híbridos para climas tropicais e temperados mostrou-se promissora para aumentar a base genética de populações de milho fresco, com ganhos satisfatórios ao longo dos cinco ciclos, com herdabilidade média de aproximadamente 78,9% para o índice relativo de clorofila, 62,2% para altura de planta, 75% para inserção da espiga, 70% para diâmetro da espiga, 56,6% para comprimento da espiga, 71,4% para espigas empalhadas e 71% para espigas comerciais entre os ciclos. disso lucratividade secos qualidade produtores Assim melhoramento Goiás casualizados 6 meios irmãos 30 ciclo repetições 20112012, 20112012 2011 2012, 2012 (2011-2012 20132014, 20132014 2013 2014, 2014 2013-2014 20152016, 20152016 2015 2016, 2016 2015-2016 20172018 2017 2018 2017-201 20202021. 20202021 2020 2021 . 2020-2021) mostrouse mostrou se 789 78 9 78,9 clorofila 622 62 2 62,2 planta 75 espiga 70 566 56 56,6 714 71 4 71,4 3 2011201 201 (2011-201 2013201 2013-201 2015201 2015-201 2017201 2017-20 2020202 202 2020-2021 7 78, 62, 5 56, 71, 201120 20 (2011-20 201320 2013-20 201520 2015-20 201720 2017-2 202020 2020-202 20112 (2011-2 20132 2013-2 20152 2015-2 20172 2017- 20202 2020-20 (2011- 2013- 2015- 2020-2 (2011 2020- (201 (20 (2 (

ABSTRACT High-intensity interval training (HIIT) can induce oxidative stress. The main aim of this study was to evaluate the effect of 15 sessions of a HIIT protocol in Wistar rats on oxidative damage markers in different tissues (blood, muscle, liver and heart). Thus, animals weighing 250-300 g were used and randomly divided into 2 groups (n= 10): Control (CG) and animals submitted to HIIT (TG) through a swimming protocol. The results showed that HIIT increased the production of malondialdehyde (MDA) in TG animals: serum (306.75%), gastrocnemius muscle (259.2%), liver (452.6%) and heart (215%), while the concentration of sulfhydryl groups decreased: serum (40%), gastrocnemius muscle (44.7%), liver (44.6%) and heart (47.2%). Thus, it could be concluded that 15 HIIT sessions altered the redox state of Wistar rats due to increased oxidative damage markers in the analysed tissues.

Abstract Objective Evaluate the effect of combined training on body image (BI), body composition and functional capacity in patients with breast cancer. As also the relationship of BI with body composition and functional capacity. Methods This was a Controlled Clinical Trial study, this study including 26 patients with breast cancer (30 to 59 years). The training group (n = 13) underwent 12 weeks of training, including three 60-min sessions of aerobic exercise and resistance training, and two sessions of flexibility training per week; each flexibility exercise lasted 20s. The Control Group (n = 13) received only the standard hospital treatment. Participants were evaluated at baseline and after 12 weeks. BI (primary outcomes) was assessed using the Body Image After Breast Cancer Questionnaire; Body composition was estimated with the indicators: Body mass index; Weight, Waist hip Ratio; Waist height ratio; Conicity index; Reciprocal ponderal index; Percentage of fat; Circumference of the abdomen and waist; Functional capacity by cardiorespiratory fitness (cycle ergometer) and strength (manual dynamometer). The statistic was performed in the Biostatistics and Stata 14.0 (α = 5%). Results The patients in the training group showed a reduction in the limitation dimension (p = 0.036) on BI, However, an increase in waist circumference was observed in both groups. In addition an increase in VO2max (p < 0.001) and strength in the right (p = 0.005) and left arms (p = 0.033). Conclusion Combined training demonstrates to be an effective and non-pharmacological strategy to patients with breast cancer, with improvement on BI and functional capacity, changing related variables negatively when there is no physical training. , (BI) 2 30 (3 5 years. years . years) n 13 1 60min min 60 week 20s s treatment primary outcomes Questionnaire indicators index Weight Ratio ratio fat cycle ergometer manual dynamometer. dynamometer dynamometer) 140 14 0 14. α 5%. 5% 5%) p 0.036 0036 036 However groups VOmax VO max 0.001 0001 001 0.005 0005 005 0.033. 0033 0.033 033 0.033) nonpharmacological non pharmacological (BI 3 ( 6 0.03 003 03 0.00 000 00 0.0 0.

Resumo Objetivo Avaliar o efeito do treinamento combinado na imagem corporal (IB), composição corporal e capacidade funcional em pacientes com câncer de mama. Assim como a relação do IB com a composição corporal e capacidade funcional. Métodos Este foi um estudo de Ensaio Clínico Controlado, este estudo incluiu 26 pacientes com câncer de mama (30 a 59 anos). O grupo de treinamento (n = 13) foi submetido a 12 semanas de treinamento, incluindo três sessões de 60 min de exercício aeróbio e treinamento de resistência, e duas sessões de treinamento de flexibilidade por semana; cada exercício de flexibilidade durou 20s. O Grupo Controle (n = 13) recebeu apenas o tratamento hospitalar padrão. Os participantes foram avaliados no início e após 12 semanas. O IB (desfechos primários) foi avaliado por meio do Body Image After Breast Cancer Questionnaire; A composição corporal foi estimada com os indicadores: índice de massa corporal; Peso, relação cintura-quadril; Relação da altura da cintura; Índice de conicidade; Índice ponderal recíproco; Porcentagem de gordura; Circunferência do abdômen e cintura; Capacidade funcional por aptidão cardiorrespiratória (cicloergômetro) e força (dinamômetro manual). A estatística foi realizada na Bioestatística e no Stata 14.0 (α = 5%). Resultados Os pacientes do grupo de treinamento apresentaram redução da dimensão da limitação (p = 0,036) no IB, porém, foi observado aumento da circunferência da cintura em ambos os grupos. Além disso, um aumento do VO2máx (p <0,001) e da força nos braços direito (p = 0,005) e esquerdo (p = 0,033). Conclusão O treinamento combinado demonstra ser uma estratégia eficaz e não farmacológica para pacientes com câncer de mama, com melhora do IB e da capacidade funcional, alterando variáveis relacionadas negativamente quando não há treinamento físico. , (IB) Controlado 2 30 (3 5 anos. anos . anos) n 13 1 6 resistência semana 20s s padrão desfechos primários Questionnaire indicadores Peso cinturaquadril quadril cintura-quadril conicidade recíproco gordura cicloergômetro (cicloergômetro dinamômetro manual. manual manual) 140 14 0 14. α 5%. 5% 5%) p 0,036 0036 036 porém grupos disso VOmáx VO máx <0,001 0001 001 0,005 0005 005 0,033. 0033 0,033 033 0,033) físico (IB 3 ( 0,03 003 03 <0,00 000 00 0,00 0,0 <0,0 0, <0, <0 <

ABSTRACT The cities of Petrópolis (RJ) and Poços de Caldas (MG) are located in the mountain range regions of their respective states in Brazil. They frequently suffer from damage caused by heavy rains. Therefore, analyzing and predicting the occurrence of maximum rainfall for these locations is fundamental for planning activities that are vulnerable to its occurrence. The modeling of this variable is done, generally, through the generalized distribution of extreme values (GEV), which the Bayesian methodology has shown good results in estimating its parameters. Therefore, the present study aimed to fit the GEV distribution to the historical series of maximum rainfall in Petrópolis and Poços de Caldas, and to evaluate different structures of prior distributions, informative and non-informative, in predicting the maximum rainfall expected for different return times. The number of successes and precision were analyzed in order to evaluate the predictions obtained with the information from the maximum rainfall of different locations to elicit the prior distribution. To obtain the posterior marginal distributions, the Monte Carlo method via Markov Chains was used. The use of informative prior distribution based on data from Poços de Caldas was more precise and accurate to predict the maximum rainfall for Petrópolis, while for Poços de Caldas, the informative prior based on information from São João da Boa Vista (SP) provided the best results. For both locations, it is expected that, in an average time of 5 years, there will be at least one day with maximum rainfall equal to or greater than 100 mm. RJ (RJ MG (MG Brazil rains Therefore done generally GEV, , (GEV) parameters distributions noninformative, noninformative non informative, non-informative times used SP (SP years 10 mm (GEV 1

Resumo As cidades de Petrópolis (RJ) e Poços de Caldas (MG) estão situadas em regiões serranas de seus respectivos estados e sofrem frequentemente com estragos provocados por fortes chuvas. Analisar e prever a ocorrência de precipitações máximas nessas localidades são fundamentais para o planejamento de atividades vulneráveis à sua ocorrência. A modelagem dessa variável é feita geralmente com distribuição generalizada de valores extremos (GEV), e a metodologia bayesiana tem apresentado bons resultados na estimação de seus parâmetros. Sendo assim, o presente estudo teve como objetivos ajustar a distribuição GEV às séries históricas de precipitação máxima de Petrópolis e Poços de Caldas e avaliar diferentes estruturas de distribuições a priori, informativas e não informativas, na predição da precipitação máxima esperada para diferentes tempos de retorno. Foram analisados o número de acertos e a precisão a fim de avaliar as previsões obtidas com as informações advindas das precipitações máximas de diferentes localidades para eliciação da distribuição a priori. A obtenção das distribuições marginais a posteriori foi realizada usando-se o método Monte Carlo via cadeias de Markov. A utilização da distribuição a priori informativa fundamentada nos dados de Poços de Caldas foi mais precisa e teve maior número de acertos para predizer as precipitações máximas para Petrópolis, enquanto para Poços de Caldas foi a priori informativa com base nas informações de São João da Boa Vista (SP). Para ambas as localidades, espera-se que, em um tempo médio de cinco anos, ocorra pelo menos um dia com precipitação máxima igual ou superior a 100 mm. RJ (RJ MG (MG chuvas GEV, , (GEV) parâmetros assim retorno usandose usando se Markov SP. SP . (SP) esperase espera que anos 10 mm (GEV (SP 1

ABSTRACT Objective To describe and compare the clinical characteristics and outcomes of patients admitted to intensive care units during the first and second waves of the COVID-19 pandemic. Methods In this retrospective single-center cohort study, data were retrieved from the Epimed Monitor System; all adult patients admitted to the intensive care unit between March 4, 2020, and October 1, 2021, were included in the study. We compared the clinical characteristics and outcomes of patients admitted to the intensive care unit of a quaternary private hospital in São Paulo, Brazil, during the first (May 1, 2020, to August 31, 2020) and second (March 1, 2021, to June 30, 2021) waves of the COVID-19 pandemic. Results In total, 1,427 patients with COVID-19 were admitted to the intensive care unit during the first (421 patients) and second (1,006 patients) waves. Compared with the first wave group [median (IQR)], the second wave group was younger [57 (46-70) versus 67 (52-80) years; p<0.001], had a lower SAPS 3 Score [45 (42-52) versus 49 (43-57); p<0.001], lower SOFA Score on intensive care unit admission [3 (1-6) versus 4 (2-6); p=0.018], lower Charlson Comorbidity Index [0 (0-1) versus 1 (0-2); p<0.001], and were less frequently frail (10.4% versus 18.1%; p<0.001). The second wave group used more noninvasive ventilation (81.3% versus 53.4%; p<0.001) and high-flow nasal cannula (63.2% versus 23.0%; p<0.001) during their intensive care unit stay. The intensive care unit (11.3% versus 10.5%; p=0.696) and in-hospital mortality (12.3% versus 12.1%; p=0.998) rates did not differ between both waves. Conclusion In the first and second waves, patients with severe COVID-19 exhibited similar mortality rates and need for invasive organ support, despite the second wave group being younger and less severely ill at the time of intensive care unit admission. COVID19 COVID 19 COVID-1 pandemic singlecenter single center study System 2020 2021 Paulo Brazil May 31 30 total 1427 427 1,42 421 (42 1,006 1006 006 (1,00 median IQR, IQR , (IQR)] 57 [5 4670 46 70 (46-70 6 5280 52 80 (52-80 years p<0.001, p0001 p p<0.001 0 001 p<0.001] 45 [4 4252 42 (42-52 4357 43 (43-57) [ 16 (1-6 26 2 (2-6) p=0.018, p0018 p=0.018 018 p=0.018] 01 (0-1 02 (0-2) 10.4% 104 10 (10.4 18.1% 181 18 p<0.001. . 81.3% 813 81 (81.3 53.4% 534 53 highflow high flow 63.2% 632 63 (63.2 23.0% 230 23 stay 11.3% 113 11 (11.3 10.5% 105 5 p=0.696 p0696 696 inhospital 12.3% 123 12 (12.3 12.1% 121 p=0.998 p0998 998 support COVID1 COVID- 202 142 1,4 (4 1,00 100 00 (1,0 (IQR) 467 7 (46-7 528 8 (52-8 p000 p<0.00 425 (42-5 435 (43-57 (1- (2-6 p001 p=0.01 (0- (0-2 10.4 (10. 18.1 81.3 (81. 53.4 63.2 (63. 23.0 11.3 (11. 10.5 p=0.69 p069 69 12.3 (12. 12.1 p=0.99 p099 99 20 14 ( 1,0 (1, (IQR (46- (52- p00 p<0.0 (42- (43-5 (1 (2- p=0.0 (0 10. (10 18. 81. (81 53. 63. (63 23. 11. (11 p=0.6 p06 12. (12 p=0.9 p09 9 (46 (52 p0 p<0. (43- (2 p=0. (8 (6 (5 p<0 (43 p=0 p< p=

ABSTRACT In family farming, mechanisation, when appropriate to the task and to the size of the property, can be one way of easing tiring and repetitive work, such as garlic harvesting. The present study is based on a model of harvester currently on the market, and proposes several improvements for mechanising the harvest on family farms, with an emphasis on sloping terrain, to reduce costs and increase productivity. Since the equipment currently on the market reduces the operational performance of these producers resulting in the high prices of commercial garlic, the aim of this study was to evaluate, using the Finite Element Method, the von Mises stresses and the displacement of a garlic harvester in different topographies. A structural analysis was carried out, and the vibration modules in the three main parts that make up the structure of the garlic harvester were checked: the structure supporting the scarifier point, the structure of the plant transport system, and the structure at the rear of the harvester. The structural modifications that were implemented corrected the initial high-stress conditions, showing improvements in stress concentration and areas of displacement. As such, the entire structure of the garlic harvester tends to withstand the proposed loads. From the results of the simulations, we conclude that the connecting support may undergo greater response from structural dynamics, and that frequencies greater than 45.7 Hz should be avoided since there are several natural frequencies above this range that might cause interference to the structure. farming mechanisation property work harvesting farms terrain productivity evaluate Method topographies out checked point system highstress conditions loads simulations dynamics 457 45 7 45. 4

Abstract Cupuassu (Theobroma grandiflorum)-based agroforestry system (AFS) can be used for restoration of vegetation around springs and riparian forests of water sources (rivers, streams, lakes etc.), subject to constant flooding. The objectives of this work were to study the relations between morphophysiological traits when flooding occurs, determining the most important to assess genotypes’ tolerance, and evaluate the ability of cupuassu genotypes to express alternative phenotypes and grow efficiently, in order to select materials capable of sustaining hypoxic conditions. The trial was carried out in a greenhouse, in a completely randomized design with a 16 x 2 (16 progenies and two water regimes) factorial scheme and four replications. Treatments started six months after the seedlings were transplanted. 15 traits related to vegetative development, biomass accumulation and physiology were measured for the experimental evaluation. Correlations and principal components were estimated to study the traits’ interrelationships and identify the most important to assist progeny selection. The results revealed that, among the evaluated traits, ten were sufficient to explain the variability within the population and four were elected as the most relevant to select the best progenies. 75% of the genotypes showed tolerance to partial flooding and based on performance and plasticity, we selected G174, G48 and G56 for a broader spectrum and G44, G47 and G51 for hypoxic conditions only. The promising evidence pointed out here will need to be corroborated with field tests, so that the cupuassu tree can be recommended in the recovery of environments subject to hypoxia. Theobroma grandiflorumbased grandiflorum AFS (AFS rivers, rivers (rivers streams etc., etc etc. , etc.) occurs efficiently greenhouse 1 (1 regimes replications transplanted development evaluation selection 75 plasticity G174 G G4 G5 G44 only tests hypoxia ( 7 G17 G1

Resumo O sistema agroflorestal (SAF) à base de cupuaçu (Theobroma grandiflorum) pode ser utilizado para a recomposição da vegetação no entorno de nascentes e de matas ciliares de mananciais (rios, córregos, lagos, etc.), sujeitos a inundações constantes. Os objetivos deste estudo foram estudar a relação entre caracteres inmorfofisiológicos sob regime de alagamento, determinando quais os mais importantes para estudar a tolerância dos genótipos e para avaliar a habilidade de genótipos decupuaçuzeiro em expressar fenótipos alternativos e crescer de forma eficiente, para seleçãode materiais capazes de suportar condições de hipóxia. O experimento foi conduzido em casa de vegetação,em delineamento inteiramente casualizado, em esquema fatorial 16 x 2 (16progênies e dois regimes hídricos) e quatro repetições. Os tratamentos iniciaram seismeses após o transplante das mudas. Para a avaliação experimental, foram medidos 15 caracteres relacionados ao desenvolvimento vegetativo, ao acúmulo de biomassa e às variáveisfisiológicas. Correlações entre características e componentes principais foram estimadas para estudar as inter-relações das características e identificar as mais responsivas paraauxiliar na seleção de genótipos. Os resultados revelaram que, dentre as característicasutilizadas, dez foram suficientes para explicar a variabilidade dentro da população e quatro foramescolhidas para selecionar as melhores progênies. 75% dos genótipos apresentaramtolerância ao alagamento parcial e, com base no desempenho e na plasticidade, foram selecionados G174, G48 e G56 para um espectro mais amplo, e G44, G47 e G51 apenas para condições de hipóxia.As evidências promissoras aqui levantadas precisarão ser corroboradas, com arealização de testes de campo, para que o cupuaçuzeiro possa ser recomendado narecuperaçãode ambientes sujeitos à hipóxia. SAF (SAF Theobroma grandiflorum rios, rios (rios córregos lagos etc., etc etc. , etc.) constantes eficiente hipóxia vegetaçãoem casualizado 1 16progênies progênies hídricos repetições mudas experimental vegetativo variáveisfisiológicas interrelações inter relações característicasutilizadas 75 plasticidade G174 G G4 G5 amplo G44 hipóxiaAs As corroboradas campo 7 G17 G1

Abstract Long-term-ecological-research (LTER) faces many challenges, including the difficulty of obtaining long-term funding, changes in research questions and sampling designs, keeping researchers collecting standardized data for many years, impediments to interactions with local people, and the difficulty of integrating the needs of local decision makers with “big science”. These issues result in a lack of universally accepted guidelines as to how research should be done and integrated among LTER sites. Here we discuss how the RAPELD (standardized field infrastructure system), can help deal with these issues as a complementary technique in LTER studies, allowing comparisons across landscapes and ecosystems and reducing sampling costs. RAPELD uses local surveys to understand broad spatial and temporal patterns while enhancing decision-making and training of researchers, local indigenous groups and traditional communities. Sampling of ecological data can be carried out by different researchers through standardized protocols, resulting in spatial data that can be used to answer temporal questions, and allow new questions to be investigated. Results can also be integrated into existing biodiversity networks. Integrated systems are the most efficient way to save resources, maximize results, and accumulate information that can be used in the face of the unknown unknowns upon which our future depends. Longtermecologicalresearch Long term (LTER challenges longterm long funding designs years people big science. science . science” sites system, system , system) studies costs decisionmaking making communities protocols investigated networks resources results depends