Resumen: Diferentes factores pueden influir en la calidad de vida de personas con discapacidad intelectual. Este estudio investigó los factores asociados con la calidad de vida relacionada con la salud oral en niños con discapacidades intelectuales desde la perspectiva de sus cuidadores. Se realizó un estudio transversal con niños brasileños institucionalizados, que fueron evaluados clínicamente y sus respectivos tutores, quienes respondieron cuestionarios. Los datos fueron recolectados a través de registros médicos, aplicación de instrumentos de evaluación y examen clínico oral (n=92). La mayoría de los niños presentaban una higiene oral deficiente (64,10%) y una experiencia de caries alta (59,8%). Si bien la percepción específicamente de las madres respecto del impacto de las condiciones de la salud oral en la calidad de vida fue baja, mostró una tendencia a aumentar en cuanto disminuía el nivel educacional, la frecuencia de cepillado y la historia de lactancia materna (p≤0.05). El hecho de que la percepción del impacto en la calidad de vida por parte de los tutores no se condiga con las precarias condiciones de salud oral exhibida por los niños con discapacidad intelectual, no sólo demuestra el desconocimiento respecto de la importancia de la salud oral en un contexto general, sino que también evidencia la necesidad de promover acciones que incentiven el cuidado y educación en relación con este aspecto, tanto en los tutores como en los niños afectados.

Abstract: Different factors can influence the perception of quality of life in individuals with intellectual disabilities. This study investigated the factors associated with quality of life related to oral health in children with intellectual disabilities from the perspective of their parents. A cross-sectional study was carried out with Brazilian children from specialized institutions and their respective guardians. Data were collected through medical records, application of instruments and oral clinical examination (n=92). Most children had poor oral hygiene (64.10%) and a high caries experience (59.8%). The mothers' perception of quality of life related to oral health was low, however there was an association of greater perception when they had low education, female child, less brushing frequency and history of breastfeeding (p≤0.05). Although the perception of quality of life was low, the oral condition found evidences the need to promote oral health education actions with children with intellectual disabilities and their respective guardians.

ABSTRACT The excess of nitrogen (N) causes the overgrowth of sweet potato foliage, increasing the self-shading and reducing the root yield. Therefore, a combined N and paclobutrazol (PBZ) application can reduce the vegetative overgrowth and benefit the sweet potato yield. The purpose of this study was to evaluate the plant growth, yield, uptake and removal of N by sweet potato plants fertilized with N and treated with PBZ during two planting seasons. The treatments consisted of four N rates (0, 50, 100 and 200 kg·ha–1), three forms of PBZ application (PBZ-10: PBZ applied at 10 days after side-dressing N fertilization [DASNF]; PBZ-25: PBZ applied at 25 DASNF, and PBZ-10 + 25: PBZ applied at 10 plus 25 DASNF), and a control (without PBZ application). Paclobutrazol application temporarily reduced the length of the main branches of sweet potato planted in the rainy season, but it did not reduce the shoot biomass of plants in both planting seasons. A single application of PBZ at 10 DASNF increased the yield of fresh storage roots in the two planting seasons, but, during the rainy season, the increases were greater when two applications were carried out. The application of 50 kg·ha–1 N in the rainy season was sufficient to reach the maximum yield of fresh storage roots, but, in the dry season, the N fertilization increased the N uptake without benefiting the root yield.

RESUMO Objetivo: elaborar e validar o conteúdo e a aparência de um guia educativo sobre a promoção da saúde vocal para a pessoa idosa. Métodos: estudo do tipo metodológico, desenvolvido em duas etapas: 1- elaboração da tecnologia educativa, com a construção do guia; 2- qualificação do material educativo com a validação do conteúdo, aparência e adequabilidade do guia por meio de 13 juízes (fonoaudiólogos) e legitimação do material educativo pelo público-alvo, 9 idosos. A validação do guia por parte dos juízes e dos idosos deu-se pelo índice de validade de conteúdo. Resultados: os aspectos da objetividade, estrutura, apresentação e relevância do conteúdo foram considerados pertinentes pelos juízes com média aproximada de 0,92. Contudo, houveram substituições e retiradas de palavras, com o intuito de trazer mais clareza ao leitor, sem prejudicar a mensagem final, além das sugestões que foram acatadas para versão final. As pessoas idosas consideraram a avaliação positiva. Conclusão: o guia educativo foi validado quanto aos aspectos de conteúdo, aparência e adequabilidade para a promoção de saúde vocal do idoso. Espera-se que o conhecimento sobre a saúde da voz promova qualidade de vida e beneficie o envelhecimento ativo e saudável.

ABSTRACT Purpose: to develop and validate the content and layout of an educational guide on promoting vocal health of older adults. Methods: a methodological study, conducted in two stages: 1 - Development of the guide as an educative technology; 2 - Qualification of the educative material with validation of the guide’s content, layout and suitability by 13 judges (speech-language-hearing pathologists) and legitimization of the educative material by the target population, 9 older adults. The validation of the guide by the judges and older adults was based on the content validity index. Results: the aspects of objectivity, structure, presentation and relevance of the content were considered pertinent by the judges with an approximate score average of 0.92. However, some words were substituted or removed to bring more clarity to the reader, without loss to the overall message, in addition to the suggestions that were accepted for the final version. The older adults returned a positive assessment. Conclusion: the educative guide was validated regarding the aspects of content, layout and suitability for the vocal health promotion of older adults. Their knowledge of voice health is expected to promote the quality of life and benefit active and healthy aging.

ABSTRACT Sweet potato crops take up large amounts of nutrients, especially nitrogen. In low-fertility soils, the addition of nitrogen (N) increases the sweet potato yield. Green manure may be an alternative method for improving soil quality and supplying nutrients to this crop. This study aimed to evaluate the plant’s nutritional status and the amount of nutrients taken up and removed by sweet potato plants subjected to green manure and mineral N fertilization. The experiment was carried out in the field for two growing seasons using a randomized block design in a split-plot scheme with four replications. The plots consisted of a control treatment (spontaneous weeds) and the previous cultivation of Crotalaria spectabilis and Mucuna aterrima. The subplots consisted of four N rates (0, 50, 100, and 200 kg ha-1) that were applied to the sweet potato. The species M. aterrima is more suitable for use as green manure in the sweet potato than C. spectabilis. Nitrogen application rates promoted a greater increase in the biomass of the storage root, nutrient uptake, and removal in the sweet potatoes unfertilized with green manure. In the sweet potato fertilized with M. aterrima, mineral N supply in excess (above 50 kg ha-1) increases the nutrient uptake and removal without a significant increase in the biomass of the storage root. In the sweet potatoes unfertilized with green manure, high rates of N (greater than 120 kg ha-1) must be applied to obtain the utmost biomass of the storage root, nutrient uptake and removal.

Resumo Aprendizagem socioemocional nem sempre é contemplada, com devido planejamento e embasamento científico, na educação infantil. Avaliou-se impacto de intervenção de Regulação Emocional (RE) no desempenho escolar e Habilidades Sociais (HS) de 55 crianças de escolas públicas, utilizando-se Matrizes Progressivas Coloridas de Raven (CPM), Teste de Desempenho Escolar e Sistema de Avaliação de Habilidades Sociais (SSRS-BR).Após nove encontros de 50 minutos abordando estratégias de RE, avaliação de HS pelo professor indicou melhora em todos os aspectos de HS noGrupo Intervenção (GI) e piora no autocontrole no GrupoComparação (GC). Autoavaliação de HS mostrou que GI superou diferença inicial na assertividadee evitação de problemas. Os resultados sugerem que programas de RE podem trazer benefícios para o desenvolvimento das HS.

Abstract In early childhood education, socio-emotional learning is not always considered with appropriate planning nor based on scientific evidence. Aiming to analyze impact of an Emotional Regulation (ER) Intervention in school achievement and social skills (SS), fifty-five children from public schools were evaluated by Raven's Coloured Progressive Matrices (CPM), School Achievement Test (TDE) and Social Skills Rating System (SSRS-BR). After nine 50-minute meetings addressing ER strategies, evaluation of SS by the teacher indicated improvement in all aspects of SS in Intervention Group (IG) and worsening of the self-control in Comparison Group (CG). Self-evaluation of SS showed that IG overcame the initial difference in assertiveness and problem avoidance. Results suggest that ER programs can bring benefits to the development of SS.

BACKGROUND In Brazil, the Yellow Fever virus (YFV) is endemic in the Amazon, from where it eventually expands into epidemic waves. Coastal south-eastern (SE) Brazil, which has been a YFV-free region for eight decades, has reported a severe sylvatic outbreak since 2016. The virus spread from the north toward the south of the Rio de Janeiro (RJ) state, causing 307 human cases with 105 deaths during the 2016-2017 and 2017-2018 transmission seasons. It is unclear, however, whether the YFV would persist in the coastal Atlantic Forest of RJ during subsequent transmission seasons. OBJECTIVES To conduct a real-time surveillance and assess the potential persistence of YFV in the coastal Atlantic Forest of RJ during the 2018-2019 transmission season. METHODS We combined epizootic surveillance with fast diagnostic and molecular, phylogenetic, and evolutionary analyses. FINDINGS Using this integrative strategy, we detected the first evidence of YFV re-emergence in the third transmission season (2018-2019) in a dying howler monkey from the central region of the RJ state. The YFV detected in 2019 has the molecular signature associated with the current SE YFV outbreak and exhibited a close phylogenetic relationship with the YFV lineage that circulated in the same Atlantic Forest fragment during the past seasons. This lineage circulated along the coastal side of the Serra do Mar mountain chain, and its evolution seems to be mainly driven by genetic drift. The potential bridge vector Aedes albopictus was found probing on the recently dead howler monkey in the forest edge, very close to urban areas. MAIN CONCLUSIONS Collectively, our data revealed that YFV transmission persisted at the same Atlantic Forest area for at least three consecutive transmission seasons without the need of new introductions. Our real-time surveillance strategy permitted health authorities to take preventive actions within 48 h after the detection of the sick non-human primate. The local virus persistence and the proximity of the epizootic forest to urban areas reinforces the concern with regards to the risk of re-urbanisation and seasonal re-emergence of YFV, stressing the need for continuous effective surveillance and high vaccination coverage in the SE region, particularly in RJ, an important tourist location.

Resumo Introdução: As doenças infecciosas, bacterianas ou virais, são uma das principais causas de morte dos pacientes com doença renal crônica (DRC), que apresentam um decréscimo na duração da imunidade em comparação às pessoas saudáveis. Entre as doenças infecciosas que acometem os portadores de DRC, destaca-se a hepatite B (HB). A imunização e o controle dos níveis de anticorpos contra o antígeno da superfície da hepatite B (anti-HBs) são formas de evitar a contaminação da HB nessa população. Pacientes com o nível de anti-HBs ≥ 10 UI/ml são considerados adequados respondedores, enquanto aqueles com níveis de anti-HBs ≥ 100 UI/ml são considerados excelentes respondedores. Objetivo: Analisar a variação dos níveis de anti-HBs adquiridos após a vacinação contra a HB em crianças e adolescentes na fase pré-dialítica da DRC. Métodos: Estudo de coorte retrospectivo dos níveis de anti-HBs de crianças e adolescentes na fase pré-dialítica da DRC. Resultados: Dos 116 pacientes do estudo, a maior parte foi considerada respondedores excelentes, obtendo nas três titulagens percentuais de 70,7%, 62,1% e 54,9%, respectivamente. Os níveis de anti-HBs apresentaram uma correlação negativa com o tempo de vacinação (Kendall Tau-b = - 0,16; p = 0,02). Conclusão: Conclui-se que a maior parte da população do estudo apresenta níveis de anti-HBs excelentes, ocorrendo uma queda progressiva da titulagem ao longo do tempo.

Abstract Introduction: Bacterial or viral diseases are one of the major causes of death in patients with chronic kidney disease (CKD). These patients show a quantitative reduction of levels of antibodies over time. Among the infectious diseases that affect CKD patients, stands out hepatitis B (HB). Immunization and control of antibodies levels against the hepatitis B surface antigen (anti-HBs) are ways to prevent the HB infection in this population. Patients with anti-HBs levels ≥10 IU/ml are considered adequate responders, whereas those with anti-HBs levels ≥ 100 IU/ml are considered excellent responders. Objective: To analyze the variation of the anti-HBs levels obtained after vaccination against HB in children and adolescents in the pre-dialysis stage of CKD. Methods: A retrospective cohort study on anti-HBs levels of children and adolescents in the pre-dialysis stage of CKD. Correlation between levels of anti-HBs titers and time since the vaccination were estimated. Results: From the total of 116 studied patients most of the studied patients were considered excellent responders, obtaining in the three anti-HBs titers percentages of 70.7%, 62.1% and 54.9% respectively. The anti-HBs titer levels showed a negative correlation with the time since vaccination (Kendall Tau-b = -0.16; p = 0.02). Conclusion: The majority of the studied population was vaccinated by PNI and showed excellent anti-HBs titer levels, even experiencing a progressive reduced response over the time.

A indústria de alimentos, buscando atender à crescente demanda dos consumidores, vem desenvolvendo embalagens ativas para proporcionar qualidade e segurança aos produtos acondicionados. Este trabalho objetivou desenvolver e avaliar a aplicação de filmes ativos aromatizados em contato com a massa de pastel. Os filmes foram preparados pelo método casting, adicionados de ácido sórbico e aroma de pizza e avaliados in vitro frente ao microrganismo Penicillium sp. Também foram estudadas suas propriedades mecânicas, migração de ácido sórbico, avaliação sensorial do produto e análise microbiológica in vivo. Os filmes ativos apresentaram atividade antimicrobiana tanto in vitro como no alimento. A caracterização mecânica mostrou que os filmes ativos aromatizados apresentaram valores de carga máxima na ruptura, inferiores ao filme controle e, durante a migração, a adição de aroma contribuiu para uma maior liberação do ácido sórbico. Além disso, as massas de pastel em contato com os filmes ativos aromatizados apresentaram melhores resultados sensoriais.

The food industry, trying to meet growing consumer demand, is developing active packaging to provide quality and safety for packed food. This research aimed to develop and evaluate the implementation of active flavored films in contact with pastry dough. The active films were evaluated for in vitro antimicrobial activity against Penicillium sp. The mechanical properties of the films, the sorbic acid migration, sensory and in vivo microbiological analyses were also tested. The active films showed better results for in vitro and in vivo microbiological analyses when compared with the film with the sorbic acid incorporated directly on the pastry dough. The incorporation of sorbic acid and flavor affected the mechanical properties of the active films compared to the control film. The flavor addition provided a larger migration of sorbic acid from the film to the pastry dough. Besides the pastry dough packed in the active films showed better sensory results.