Resumo Fundamento A fibrilação atrial (FA) é uma complicação prevalente associada à levosimendana; no entanto, permanece incerto se existem disparidades nos efeitos da levosimendana na FA não pós-operatória e pós-operatória. Objetivos Este estudo teve como objetivo avaliar o efeito da levosimendana na FA não pós-operatória e pós-operatória conduzindo uma metanálise de ensaios clínicos randomizados (ECR). Métodos PubMed, Embase, Biblioteca Cochrane e outras bases de dados foram pesquisadas. Pares de revisores identificaram ECRs que compararam levosimendana e placebo ou outras terapias, e os resultados relataram dados de eventos de FA. Foram utilizados modelos de efeitos aleatórios (com nível de significância de 5%). Resultados Foram incluídos 29 ensaios elegíveis compreendendo 6.550 participantes, onze dos quais avaliaram a incidência de FA não pós-operatória e 18 incluíram FA pós-operatória. A análise revelou que a levosimendana elevou significativamente o risco de FA no grupo não pós-operatório (OR, 1,62; IC 95%: 1,19-2,20; p=0,002) e reduziu a incidência de FA no grupo pós-operatório (OR, 0,65; IC 95%: 0,44-0,96; p=0,03). A ocorrência de FA diminuiu mais significativamente em pacientes que usaram levosimendana após cirurgia cardíaca (OR, 0,53; IC 95%: 0,32-0,88; p=0,02) do que em pacientes que usaram levosimendana antes da cirurgia cardíaca (OR, 0,67; IC 95%: 0,42-1,06; p=0,09). O risco de FA foi significativamente elevado pela grande dose em bolus de levosimendana (dose em bolus ≥12 μg/kg) (OR, 1,44; IC 95%: 1,10-1,88; p=0,004) e diminuído pela pequena dose em bolus de levosimendana (dose em bolus <12 μg/kg) (OR, 0,64; IC 95%: 0,34-1,20; p=0,16). Conclusão A levosimendana foi associada a um aumento da incidência de FA não pós-operatória. O emprego da levosimendana foi eficaz na prevenção da FA pós-operatória. (FA entanto pósoperatória pós operatória pósoperatória. operatória. ECR. ECR . (ECR) PubMed Embase pesquisadas terapias com 5%. 5 5% 5%) 2 6550 6 550 6.55 participantes 1 pósoperatório operatório OR, OR (OR 1,62 162 62 95% 95 1,192,20 119220 1,19 2,20 19 20 1,19-2,20 p=0,002 p0002 p 0 002 0,65 065 65 0,440,96 044096 0,44 0,96 44 96 0,44-0,96 p=0,03. p003 p=0,03 03 p=0,03) 0,53 053 53 0,320,88 032088 0,32 0,88 32 88 0,32-0,88 p=0,02 p002 02 0,67 067 67 0,421,06 042106 0,42 1,06 42 06 0,42-1,06 p=0,09. p009 p=0,09 09 p=0,09) 12 ≥1 μg/kg μgkg μg kg 1,44 144 1,101,88 110188 1,10 1,88 10 1,10-1,88 p=0,004 p0004 004 <1 0,64 064 64 0,341,20 034120 0,34 1,20 34 0,34-1,20 p=0,16. p016 p=0,16 16 p=0,16) (ECR 655 55 6.5 1,6 9 192 1,192,2 11922 119 1,1 220 2,2 1,19-2,2 p=0,00 p000 00 0,6 440 0,440,9 04409 044 0,4 096 0,9 4 0,44-0,9 p00 p=0,0 0,5 05 320 0,320,8 03208 032 0,3 088 0,8 3 8 0,32-0,8 421 0,421,0 04210 042 106 1,0 0,42-1,0 ≥ 1,4 14 101 1,101,8 11018 110 188 1,8 1,10-1,8 < 341 0,341,2 03412 034 120 1,2 0,34-1,2 p01 p=0,1 6. 1, 1,192, 1192 11 22 2, 1,19-2, 0, 0,440, 0440 04 0,44-0, p0 p=0, 0,320, 0320 08 0,32-0, 0,421, 0421 0,42-1, 1,101, 1101 1,10-1, 0,341, 0341 0,34-1, 1,192 1,19-2 0,440 0,44-0 p=0 0,320 0,32-0 0,421 0,42-1 1,101 1,10-1 0,341 0,34-1 1,19- 0,44- p= 0,32- 0,42- 1,10- 0,34-

Abstract Background Atrial fibrillation (AF) is a prevalent complication associated with levosimendan; however, it remains uncertain whether there are any disparities in the effects of levosimendan on non-postoperative and postoperative AF. Objectives This study aimed to evaluate the levosimendan effect on non-postoperative and postoperative AF by conducting a meta-analysis of randomized control trials (RCTs). Methods PubMed, Embase, Cochrane Library, and other databases were searched. Pairs of reviewers identified RCTs that compared levosimendan and placebo or other therapies, and the results reported AF events data. Random effects models were used (at a significance level of 5%). Results Twenty-nine eligible trials comprising 6550 participants were included, eleven of which evaluated the non-postoperative AF incidence, and 18 included postoperative AF. The analysis revealed that levosimendan elevated the AF risk significantly in the non-postoperative group (OR, 1.62; 95% CI: 1.19-2.20; p=0.002) and reduced the AF incidence in the postoperative group (OR, 0.65; 95% CI: 0.44-0.96; p=0.03). AF occurrence decreased more significantly in patients who used levosimendan after cardiac surgery (OR, 0.53; 95% CI: 0.32-0.88; p=0.02) than in patients who used levosimendan before cardiac surgery (OR, 0.67; 95% CI: 0.42-1.06; p=0.09). Moreover, The AF risk was significantly elevated by levosimendan large bolus dose (bolus dose≥12 μg/kg) (OR, 1.44; 95% CI: 1.10-1.88; p=0.004) and decreased by small bolus dose of levosimendan (bolus dose<12 μg/kg) (OR, 0.64; 95% CI: 0.34-1.20; p=0.16). Conclusion Levosimendan was linked to an increased non-postoperative AF incidence. The employment of levosimendan was effective in preventing postoperative AF. (AF however nonpostoperative non metaanalysis meta RCTs. . (RCTs) PubMed Embase Library searched therapies data at 5%. 5 5% 5%) Twentynine Twenty nine 655 1 OR, OR (OR 1.62 162 62 95 CI 1.192.20 119220 1.19 2.20 19 2 20 1.19-2.20 p=0.002 p0002 p 0 002 0.65 065 65 0.440.96 044096 0.44 0.96 44 96 0.44-0.96 p=0.03. p003 p=0.03 03 p=0.03) 0.53 053 53 0.320.88 032088 0.32 0.88 32 88 0.32-0.88 p=0.02 p002 02 0.67 067 67 0.421.06 042106 0.42 1.06 42 06 0.42-1.06 p=0.09. p009 p=0.09 09 p=0.09) Moreover dose12 12 dose≥1 μg/kg μgkg μg kg 1.44 144 1.101.88 110188 1.10 1.88 10 1.10-1.88 p=0.004 p0004 004 dose<1 0.64 064 64 0.341.20 034120 0.34 1.20 34 0.34-1.20 p=0.16. p016 p=0.16 16 p=0.16) (RCTs 1.6 6 9 192 1.192.2 11922 119 1.1 220 2.2 1.19-2.2 p=0.00 p000 00 0.6 440 0.440.9 04409 044 0.4 096 0.9 4 0.44-0.9 p00 p=0.0 0.5 05 320 0.320.8 03208 032 0.3 088 0.8 3 8 0.32-0.8 421 0.421.0 04210 042 106 1.0 0.42-1.0 dose1 dose≥ 1.4 14 101 1.101.8 11018 110 188 1.8 1.10-1.8 dose< 341 0.341.2 03412 034 120 1.2 0.34-1.2 p01 p=0.1 1. 1.192. 1192 11 22 2. 1.19-2. 0. 0.440. 0440 04 0.44-0. p0 p=0. 0.320. 0320 08 0.32-0. 0.421. 0421 0.42-1. 1.101. 1101 1.10-1. 0.341. 0341 0.34-1. 1.192 1.19-2 0.440 0.44-0 p=0 0.320 0.32-0 0.421 0.42-1 1.101 1.10-1 0.341 0.34-1 1.19- 0.44- p= 0.32- 0.42- 1.10- 0.34-

Abstract The woody oil industry generates a large amount of seed shell waste during its production. Therefore, this paper employs a central composite design (CCD) methodology to optimize the ultrasonic-assisted extraction process, thus utilizing the byproduct. The infrared spectrum and thermogravimetric analysis is adopted to explore the chemical structure and thermal stability of tannin. Besides, the tannin resin (TF) is prepared to elaborate its adsorbing performance for dyes in water. The results verify the role of ultrasonic-assisted extraction method in increasing yield rate. The optimal conditions are as follows: 60% ethanol as extraction solvent, the solid-liquid ratio of 1:25 (g/mL), ultrasonic power of 160 W, and extracted at 80oC for 60min. The yield rate of tannin under such conditions stands at 32.04% (w/w). Temperature is vital for the extraction rate. Acer truncatum tannin as a condensed tannin, performs favorable thermal stability, and TF effectively absorbs cationic dye in water. The maximum adsorption capacity of methylene blue peaks at 176.13 mg/g. Acer truncatum shell serves as a resource of condensed tannin, and Acer truncatum tannin resin can be potentially developed into a new biomass adsorbent. production Therefore CCD (CCD ultrasonicassisted assisted process byproduct Besides (TF water follows 60 solvent solidliquid solid liquid 125 1 25 1:2 g/mL, gmL g/mL , g mL (g/mL) 16 W oC 60min min 3204 32 04 32.04 w/w. ww w/w . w (w/w) 17613 176 13 176.1 mgg mg mg/g adsorbent 6 12 2 1: (g/mL 320 3 0 32.0 (w/w 1761 17 176. 32.

Abstract The fruit softening seriously affected the quality of Annona squamosa, and the edible coating combined with exogenous calcium had a positive effect on inhibiting the softening of A. squamosa. In this paper, the rheological properties of C-AeP-P solution and the effect of Ca2+ on the rheological properties of the solution were studied. Based on this, the indicators of fruit hardness, freshness and plumpness were used to monitor the softening effect of A. squamosa. The results show that: C-AeP-P solution showed non-Newtonian shear-thinning behavior over the range of 0.2-1.0%. With the increase of C-AeP-P concentration, the apparent viscosity and solids like properties increased. After the addition of Ca2+, C-AeP-P had apparent differences on apparent viscosity. The G′ and G″ of C-AeP-P were increased with increasing oscillation frequency. C-AeP-P and C-AeP-P+Ca2+ treatment can slow down rapidly decline of fruit hardness, increase of soluble solid content, loss of water, change peel color and regulate the expression of key enzyme genes AI and Ni. It was concluded that the coating treatment of C-AeP-P alleviates the adverse effects of quality changes during storage, so as to improve the quality and prolong the shelf life of A. squamosa. squamosa A paper CAePP C AeP P Ca2 Ca studied hardness nonNewtonian non Newtonian shearthinning shear thinning 0.21.0%. 0210 0.2 1.0%. 0 2 1 0.2-1.0% concentration G frequency CAePP+Ca2+ CAePPCa2 CAePPCa P+Ca2+ C-AeP-P+Ca2 content water Ni storage 21 0.21.0% 021 02 0. 10 1.0% 0.2-1.0 CAePP+Ca2 PCa2 PCa P+Ca2 C-AeP-P+Ca 0.21.0 1.0 0.2-1. CAePP+Ca P+Ca 0.21. 1. 0.2-1 0.21 0.2-

ABSTRACT The selection of key additive materials for a new type of oil-based drilling fluid was studied in this paper. The oil-based drilling fluid can strengthen well walls and ensure safety. It is suitable for high-temperature and high-pressure wells, deep wells and ultra-deep wells. A new type of high-temperature white oil-based drilling fluid was prepared by using 5# white oil as continuous phase, HIS as thickening agent, SDBS as emulsifier, and asphalt powder oxidized at 180°C as filtration agent. The results showed that the saturation concentration of sodium dodecyl benzene sulfonate (SDBS) was 4%, the saturation concentration of asphalt powder oxidized at 180°C was 4%, the saturation concentration of Tween-80 was 10%. The final resistance of high temperature and high pressure oil based drilling fluid formulation material is: No. 5 white oil + 4% SDBS + 5% modified bentonite + 4% asphalt powder oxidized at 180°C + 10% Tween-80 + 1.5% Barite + CaO. The performance evaluation of the new oil-based drilling fluid shows that shale expansion is 0.21mm, anti-temperature up to 220°C, and anti-pollution ability is good. The rheological properties, resistance of high-temperature high- pressure have been greatly improved. Therefore, the new white oil-based drilling fluid can resistance of high- temperature and also has low toxicity, which can meet the exploration and development of more complex wells. oilbased paper safety hightemperature highpressure ultradeep ultra phase agent emulsifier 180C C 180 (SDBS 4 Tween80 Tween 80 Tween-8 10 No 15 1 1.5 CaO 021mm mm 0 21mm 0.21mm antitemperature anti 220C 220 220°C antipollution pollution good properties improved Therefore toxicity 18 Tween8 8 Tween- 1. 22 2

Abstract Aiming to provide a new way that preserves more active components in Eucommia ulmoides (EU) leaves, this paper utilizes 4 methods, i.e., microwave, steam, air heating, and frying, to process EU leaves before drying, and their respective effects on the leaves were evaluated. The antioxidant activity of EU leaves in vitro was measured by the DPPH free radical method; the contents of total flavonoids (TFC) and total phenols (TPC) were analyzed by spectrophotometry; and the contents of main active components were determined by high-performance liquid chromatography (HPLC). The results showed the pre-process improved the quality of the EU leaves. As a simple and fast process, the microwave process is the most effective technique in the retention of flavonoids and four active ingredients except aucubin. High power (800 W) and short time (2.5 min) are more conducive to the retention of active ingredients, with high antioxidant activity. Appropriate steam and frying processes also exhibited benefits for the active components. In particular, the samples treated with steam for 10 minutes showed great potential for industrial application with the highest antioxidant activity and polyphenol content. Therefore, proper pre-processing before drying should be conducted to effectively protect the active components of EU leaves.

Abstract Introduction: Drug-eluting stents (DES) coated with rapamycin or paclitaxel as antiproliferative substances significantly reduced the incidence of clinical restenosis and had fewer side effects after percutaneous coronary intervention. However, DES coated with rapamycin or paclitaxel still cause restenosis due to abnormal tissue growth which remained a therapeutic problem, particularly in certain subgroups, possibly due to drug concentrations. This study examined the impact of different concentrations of rapamycin and paclitaxel on cytokine, cell viability and proliferation in human aortic smooth muscle cells (HASMC)-derived foam cells. Methods: The foam cell model was established in vitro by incubating HASMC with 20 µg/mL oxidized low-density lipoprotein (ox-LDL) for 48 hours. Subsequently, foam cells were treated with different concentrations (0.01 µg/mL, 0.1 µg/mL, 0.5 µg/mL, 1 µg/mL, 5 µg/mL and 10 µg/mL) of rapamycin or paclitaxel for 48 hours, to measure cytokine, cell viability and proliferation by ELISA and MTT, respectively. Finally, viability and proliferation were measured by MTT after the foam cells were treated with 1 µg/mL rapamycin or paclitaxel combined with cytokine antibody for 48 hours. Results: After incubation of HASMC with ox-LDL, the ratios of cholesterol ester and total cholesterol increased significantly (55.29%) (P<0.01). Lipid staining with Oil Red O showed many lipid vacuoles and red dye particles in the cells. Meanwhile, cell viability and proliferation significantly increased compared with the control. This indicated that HASMC had been transformed into foam cells (P<0.01) while rapamycin or paclitaxel concentrations ≥0.1 µg/mL can significantly decrease the foam cell proliferation (P<0.05 or P<0.01), and 1 µg/mL of rapamycin or paclitaxel appeared the most effective concentration. As for cytokines, rapamycin or paclitaxel concentrations ≥1 ug/mL could significantly increase the level of inflammatory cytokines IL-6 (P<0.05 or P<0.01), which was enhanced with the increase of drug concentration. However, rapamycin or paclitaxel concentrations ≥1 µg/mL could significantly reduce the levels of anti-inflammatory cytokines IL-35 and transforming growth factor beta (TGF-β) (P<0.05 or P<0.01), which decreased with the increase of drug concentration. In addition, rapamycin or paclitaxel combined with anti-IL-1β, anti-IL-6, anti- TNF-α or anti-IL-35 had no significant effect on foam cell proliferation compared to the drug alone. However, rapamycin or paclitaxel combined with anti-IL-10 or anti-TGF-β can significantly enhance foam cell proliferation (P<0.01). In addition, there was no difference in the effects of the same concentrations of rapamycin and paclitaxel on foam cells. Conclusion: Although rapamycin or paclitaxel can reduce foam cell proliferation, too high or too low concentrations could decrease effectiveness. In particular, a high dose can induce foam cells to increase inflammatory cytokines secretion, reduce anti-inflammatory cytokines secretion, and thus affect the inhibiting proliferation. For rapamycin- and paclitaxel-eluting stents, this conclusion may explain the clinical observation of in-stent restenosis after percutaneous coronary intervention. DES coated with an appropriate concentration of rapamycin or paclitaxel may, at least to some extent, contribute significantly to reducing incidence of late in-stent restenosis.

Abstract To conduct centralized management combined with Information system application management in radiology instruments and reusable medical devices, and explore the promotion value of cleaning quality and work efficiency. The recycling time, cleaning quality, packaging quality and distribution errors of the devices with which centralized management combined with Information system application management (June 2019) was implemented half a year before and after in the radiology department of our hospital were collected and compared. With implementation of centralized management combined with Information system application management, the average recycling time (25.33 ± 5.64) of devices was remarkably shorter than that before implementation (42.37 ± 6.77) (P < 0.05). The yield of cleaning (94.57%) and packaging (98.91%) in the observation group were significantly higher than those in the control group (86.05%) and (87.21%) (P < 0.05). The probability of distribution error (8.70%) and recycling error (5.43%) of devices in the observation group were significantly lower than those in the control group (19.77% and 18.60%) (P < 0.05). Centralized management combined with Information system application management effectively improves the cleaning quality and work efficiency of radiology instruments and reusable instruments, indicating long-term application value.

ABSTRACT Calligonum is the only C4 genus within Polygonaceae. We applied DNA sequences from the nuclear ribosomal internal transcribed spacer (nrITS) and five plastid genome regions (psbA-trnH, ycf6-psbM, trnL-F, rpl32-trnL and rbcL) to reconstruct the phylogeny of Calligonum. The nrITS and the combined plastid DNA regions were analysed separately. The phylogeny of the five plastid genome regions supports the treatment of the Calligonum mongolicum complex as a single species with intra-specific geographic structure, and suggests independent hybrid origins for the polyploid species C. caput-medusae and C. arborescens through comparisons with the nrITS tree. We detected phylogenetic incongruence between the nrITS and plastid DNA trees and hypothesized reticulate evolution or hybrid speciation in the genus. Divergence time dating based on nrITS determined that the most recent common ancestor of Calligonum species began diversification 3.46 million years ago [mya; 95 % high probability density (HPD): 1.87-5.71 mya], and diversification began in the Central Asia and China clade ca. 2.68 mya (95 % HPD: 1.28-4.59 mya). We expect that future studies employing next generation sequencing methods, such as RAD-seq, coupled with denser inter- and intra- specific taxonomic sampling, may prove to be cost-effective methods for further investigation of the evolutionary history of this genus.

The present study aimed to investigate the protective effects of salidroside on chronic heart failure (CHF) in rats and to explore the underlying mechanisms. One hundred SD rats were randomly divided into sham-operated, model, and low-, medium- and high-dose salidroside groups. The CHF model was established in later 4 groups. The later 3 groups were intragastrically administrated with 6, 12 and 24 mg/kg salidroside, respectively, once a day, for continuous 4 weeks. Finally, the serum levels of brain natriuretic peptide (BNP) and interleukin 6 (IL-6), cardiac function indexes, and expression levels of myocardial cysteinyl aspartate-specific proteinase (Caspase)-3, Caspase-9, matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) protein were determined. Results showed that, after treatment, compared with model group, in high-dose salidroside group the heart function indexes were significantly improved (P < 0.05), the serum levels of BNP and IL-6 were significantly decreased (P < 0.05), the expression levels of myocardial Caspase-3, Caspase-9 and MMP-1 protein were significantly decreased (P < 0.05), and the expression level of TIMP-1 protein was significantly increased (P < 0.05). In conclusion, salidroside has obvious protective effects on CHF in rats. The mechanisms may be related to its regulation of cardiomyocyte apoptosis and ventricular remodelingregulation related protein expressions.

The influence of homogenization treatment on microstructure evolution of Mg-5.8Zn-0.5Zr-1.0Yb (mass fraction, %) alloy was investigated under different annealing temperatures and holding times. Results indicated a severe dendritic segregation in the as-cast ingot. Zn and Yb segregate remarkably at the grain boundary and Zr appears in the form of precipitates. The Mg-Zn binary eutectic phases and a new ternary phase Mg-Zn-Yb are mainly distributed at dendrite boundaries. After homogenization, most of the eutectic phases dissolve into the matrix, except for a small amount of Mg-Zn-Yb phase. The area fractions of residual secondary phase decrease from 5.54% in the as-cast alloy to 0.59% in the well-homogenized sample. Microhardness test indicates that with the increasing temperature and holding time, microhardness value decreased sharply within the first stage of homogenization and then increased steadily to the local maximum value at 380 ºC and 12 h, followed by a slight reduction. Basing on the comprehensive analysis on microstructure and mechanical properties, the homogenization treatment at 380 ºC for 12 h is preferable.

Abstract The aim of this paper is to identify and investigate an endophytic fungus (strain 28) that was isolated from Houttuynia cordata Thunb, a famous and widely-used Traditional Chinese Medicine. Based on morphological methods and a phylogenetic analysis of ITS sequences, this strain was identified as Chaetomium globosum. An antifungal activity bioassay demonstrated that the crude ethyl acetate (EtOAc) extracts of strain 28 had a wide antifungal spectrum and strong antimicrobial activity, particularly against Exserohilum turcicum (Pass.) Leonard et Suggs, Botrytis cinerea persoon and Botrytis cinerea Pers. ex Fr. Furthermore, the fermentation conditions, extraction method and the heat stability of antifungal substances from strain 28 were also studied. The results showed that optimal antifungal activity can be obtained with the following parameters: using potato dextrose broth (PDB) as the base culture medium, fermentation for 4–8 d (initial pH: 7.5), followed by extraction with EtOAc. The extract was stable at temperatures up to 80 °C. This is the first report on the isolation of endophytic C. globosum from H. cordata to identify potential alternative biocontrol agents that could provide new opportunities for practical applications involving H. cordata.

Rapid solidification of the super high-temperature Al2O3/ZrO2 melt was studied by a novel method. The melt was prepared by explosion reaction using Al and Zr(NO3)4 as raw materials and then sprayed to Cu-plate. The heat transfer during the solidification process was analyzed by one-dimensional Finite Element Analysis. The cooling rate of the melt decreased with the increasing distance from the Cu-plate. According to the microstructure evolution, the coating can be divided into four areas: amorphous, nano-crystalline, cellular and dendrite crystal layer. The amorphous and nano-crystalline (50~100 nm) layers can be obtained at the cooling rate of about 1.68~7.76 × 105K/s and 0.48~1.68 × 105K/s, respectively, while the cooling rate of the cellular and dendrite crystal layers were about 0.26~0.48 × 105K/s and 0.14~0.26 × 105K/s, respectively. The microstructure of the hypoeutectic ceramics shows that the nano-crystalline, cellular and dendritic crystals of the Al2O3 phases were embedded in the Al2O3/ZrO2 eutectic matrix.

Background: Overweight and obesity are epidemic worldwide. The purpose of this research is to estimate whether the prevalence of obesity among primary school children is high, and to identify its potential determinants to optimize the methods of prevention to combat further increases in childhood overweight. Methods: A cross-sectional study was designed to collect the routine health screening data for primary school children in Wannan area, China. Overweight and obesity status were determined using the International Obesity Task Force standard (IOTF) BMI cut-off points. Results: A total of 67956 subjects (36664 male and 31292 female) aged 5-14 years were recruited in this study. Depending on the references used (IOTF), the overall prevalence of overweight, including obesity of the subjects was 17.85% , the prevalence of overweight, including obesity was 22.9% in male subjects and 11.9% in female subjects, respectively. The overall prevalence of obesity was3.7%, the prevalence of obesity was 5.2 % in male subjects and 1.8% in female subjects, respectively. An interesting observation made was that the prevalence of overweight was high in male subjects. Conclusions: Overweight is prevalence among primary school children, especially in male children. The relate department of school and government should take some measure to reduce the prevalence of overweight and obesity.

Antecedentes: El sobrepeso y la obesidad son epidemia en todo el mundo. El propósito de esta investigacion es estimar si la prevalencia de la obesidad entre los niños de la escuela primaria es alto, y a identificar sus posibles factores determinantes para optimizar los métodos de prevención para combatir nuevas subidas en sobrepeso infantil. Métodos: Un estudio transversal fue diseñado para recoger los exámenes de salud de rutina datos para la escuela primaria los niños de 5 a 14 años en Wannan Area, China, el sobrepeso y la obesidad se determinaron utilizando la International Obesity Task Force Standard (IOTF) IMC puntos de corte. Resultados: Un total de 67956 sujetos (36664 macho y 31239 hembra) de 5 a 14 años fueron reclutados en este estudio. Dependiendo de las referencias utilizadas (IOTF), la prevalencia de sobrepeso, incluyendo la obesidad de los sujetos fue 17,85%, la prevalencia de sobrepeso, incluyendo la obesidad fue del 22,9% en sujetos masculinos y el 11,9% en mujeres, respectivamente. La prevalencia global de la obesidad was 3,7%, la prevalencia de obesidad fue de 5,2% en sujetos masculinos y 1,8% de mujeres, respectivamente. Una observación interesante es que la prevalencia de sobrepeso fue alta en sujetos masculinos. Conclusiones: El sobrepeso es la prevalencia entre los niños de la escuela primaria, especialmente en los niños varones. escuela y Departamento de Gobierno debería tomar algo de placer para reducir la prevalencia del sobrepeso y la obesidad.