Pesquisa | SciELO

ABSTRACT BACKGROUND: Specific types of violence such as intimate partner sexual violence and intimate partner homicide occur more frequently in rural areas. OBJECTIVE: This study aimed to systematically review the literature on the knowledge and attitudes of rural healthcare providers regarding cases of domestic violence against women. DESIGN AND SETTING: Systematic review developed at Universidade Federal de Uberlândia. METHODS: We conducted an electronic search of six databases, which only included observational studies, regardless of the year, language, or country of publication, except for studies that used secondary data and were exclusively qualitative. Two reviewers performed the selection, data extraction, and risk of bias assessment using a specific Joanna Briggs Institute tool. RESULTS: Six studies met the inclusion criteria. All the studies had a low risk of bias. Approximately 38% of these professionals identified injuries caused by violence in patients. When asked about knowing the correct attitude to take in cases of confirmed violence, between 12% and 64% of rural healthcare providers answered positively; most of them would refer to specialized institutions and promote victim empowerment and counseling. The number of professionals with an educational background in the field ranged from 16% to 98%. CONCLUSIONS: The evident disparity across studies shows that some professionals have suboptimal knowledge and require training to adopt the correct attitude when identifying female victims of domestic violence in clinical practice. SYSTEMATIC REVIEW REGISTRATION: This systematic review was registered in the Open Science Framework Database under the registration http://doi.org/10.17605/OSF.IO/B7Q6S. BACKGROUND areas OBJECTIVE women SETTING Uberlândia METHODS databases year language publication qualitative selection extraction tool RESULTS criteria 38 patients 12 64 positively counseling 16 98 98% CONCLUSIONS practice REGISTRATION http//doi.org/10.17605/OSF.IO/B7Q6S. httpdoiorg1017605OSFIOB7Q6S httpdoiorgOSFIOBQS http //doi.org/10.17605/OSF.IO/B7Q6S. doi org 10 17605 OSF IO B7Q6S B Q S http://doi.org/10.17605/OSF.IO/B7Q6S 3 1 6 9 http//doi.org/10.17605/OSF.IO/B7Q6S httpdoiorg OSFIOB doiorg1017605OSFIOB7Q6S doiorgOSFIOBQS //doi.org/10.17605/OSF.IO/B7Q6S 1760 BQS doiorg 176 17

https://doi.org/10.1590/1516-3180.2022.0682.r1.180723

Analysis of the access of pregnant women to the first programmatic dental appointment: an ecological study appointment
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MARIOTTI, Camila

; SOUZA, Leiriane Alves de

; PARANHOS, Luiz Renato

; BULGARELI, Jaqueline Vilela

; HERVAL, Álex Moreira

Brazilian Oral Research

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2024, Volume 38 elocation e012

Resumo: En | Texto: En | PDF: En

Abstract To plan and evaluate public health policies, it is important to understand the influence of social factors on the quality and access to dental care. This study aimed to verify the potential association between the indicators of pregnant women receiving dental care and the social and health care indicators of cities in the Brazilian state of Minas Gerais. A cross-sectional ecological study was performed with secondary data from the Brazilian Institute of Geography and Statistics and the Health Care Department of the Ministry of Health regarding the cities of Minas Gerais. The study analyzed three health care indicators (such as more than six prenatal, the proportion of syphilis and human immunodeficiency virus tests, and oral health coverage) and four social indicators (average monthly wage, illiteracy rate, proportion of employed population, and rate of adequate sanitary sewerage). Bivariate analysis (Mann-Whitney test) and logistic regression were performed using Jamovi software. All of the indicators analyzed were associated with the access of pregnant women to dental care. However, in the regression models, only health care indicators remained statistically significant. Thus, although social indicators are associated with the access of pregnant women to dental appointments, access to primary health care and the teamwork of primary health care teams may overcome social inequality in the access of pregnant women to dental care. policies Gerais crosssectional cross sectional such prenatal tests coverage average wage population sewerage. sewerage . sewerage) MannWhitney Mann Whitney test software However models significant Thus appointments

https://doi.org/10.1590/1807-3107bor-2024.vol38.0012

Suicide ideation and psychotropic recreational drug use by adolescents: a systematic review and meta-analysis adolescents metaanalysis meta analysis
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Oliveira Gracini, Cássia Lima de

; Nascimento, Gustavo Giacomelli

; Vidigal, Maria Tereza Campos

; Oliveira, Murilo Navarro de

; Herval, Álex Moreira

; Blumenberg, Cauane

; Vieira, Walbert A.

; Lima, Rafael Rodrigues

; Paranhos, Luiz Renato

Sao Paulo Medical Journal

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2024, Volume 142 Nº 4 elocation e2022641

Resumo: En | Texto: En | PDF: En

ABSTRACT BACKGROUND: Adolescence is characterized by complex and dynamic changes, often involving experimentation, including the use of psychotropic substances. Although it is well-established that recreational psychotropic drugs are associated with suicide ideation in adults, evidence of this association in adolescents remains limited. OBJECTIVE: To investigate the relationship between suicide ideation and psychotropic recreational drug use among adolescents. DESIGN AND SETTING: Systematic review with meta-analysis developed at Universidade Federal de Uberlândia (UFU) and Universidade Estadual de Campinas (UNICAMP), Brazil. METHODS: A search across eight electronic databases for observational studies, without language or publication year restrictions, was conducted. The Joanna Briggs Institute tool was used to assess the risk of bias. Random-effects meta-analyses and odds ratios were used to measure the effects. RESULTS: The search yielded 19,732 studies, of which 78 were included in the qualitative synthesis and 32 in the meta-analysis. The findings indicated that suicidal ideation was 1.96 times more likely (95% confidence interval, CI = 1.47; 2.61) for adolescents who used some drug recurrently and 3.32 times more likely (95%CI = 1.86; 5.93) among those who abused drugs. Additionally, adolescents who used cannabis were 1.57 times more likely (95%CI = 1.34; 1.84) to experience suicide ideation compared with non-users, while cocaine users had 2.57 times higher odds (95%CI = 1.47; 4.50). CONCLUSIONS: Psychotropic recreational drug use is associated with suicidal ideation among adolescents regardless of current or previous use, abuse, or type of substance used. SYSTEMATIC REVIEW REGISTRATION: Registered in the PROSPERO database under the identification number CRD42021232360. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021232360. BACKGROUND changes experimentation substances wellestablished well established adults limited OBJECTIVE SETTING metaanalysis meta analysis UFU (UFU UNICAMP, UNICAMP , (UNICAMP) Brazil METHODS studies restrictions conducted bias Randomeffects Random effects metaanalyses analyses RESULTS 19732 19 732 19,73 7 3 metaanalysis. analysis. 196 1 96 1.9 95% 95 (95 interval 1.47 147 47 2.61 261 2 61 332 3.3 95%CI 95CI 1.86 186 86 5.93 593 5 93 Additionally 157 57 1.5 1.34 134 34 1.84 184 84 nonusers, nonusers non users, non-users 257 2.5 4.50. 450 4.50 . 4 50 4.50) CONCLUSIONS abuse REGISTRATION CRD42021232360 CRD https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD42021232360. httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD42021232360 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD https //www.crd.york.ac.uk/prospero/display_record.php ID=CRD42021232360. www crd york ac uk prospero display record php ID https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021232360 (UNICAMP 1973 73 19,7 9 1. (9 1.4 14 2.6 26 6 33 3. 1.8 18 8 5.9 59 15 1.3 13 25 2. 45 4.5 CRD4202123236 phpID https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD42021232360 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD4202123236 wwwcrdyorkacukprosperodisplayrecordphp IDCRD42021232360 IDCRD ID=CRD42021232360 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD4202123236 197 19, ( 5. 4. CRD420212323 https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD4202123236 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD420212323 IDCRD4202123236 ID=CRD4202123236 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD420212323 CRD42021232 https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD420212323 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD42021232 IDCRD420212323 ID=CRD420212323 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021232 CRD4202123 https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD42021232 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD4202123 IDCRD42021232 ID=CRD42021232 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD4202123 CRD420212 https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD4202123 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD420212 IDCRD4202123 ID=CRD4202123 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD420212 CRD42021 https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD420212 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD42021 IDCRD420212 ID=CRD420212 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021 CRD4202 https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD42021 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD4202 IDCRD42021 ID=CRD42021 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD4202 CRD420 https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD4202 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD420 IDCRD4202 ID=CRD4202 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD420 CRD42 https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD420 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD42 IDCRD420 ID=CRD420 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42 CRD4 https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD42 httpswwwcrdyorkacukprosperodisplayrecordphpIDCRD4 IDCRD42 ID=CRD42 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD4 https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD4 IDCRD4 ID=CRD4 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD https//www.crd.york.ac.uk/prospero/display_record.phpID=CRD ID=CRD

https://doi.org/10.1590/1516-3180.2022.0641.r2.23012024

Atenção odontológica durante a gestação e a saúde do recém-nascido: um estudo transversal recémnascido recém nascido recém-nascido
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MARIOTTI, Camila

; SANTOS, Camila Maura Morais Lima dos

; BULGARELI, Jaqueline Vilela

; PARANHOS, Luiz Renato

; HERVAL, Álex Moreira

Revista de Odontologia da UNESP

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2024, Volume 53 elocation e20240006

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Verificar a existência de relação entre a atenção odontológica à gestante e as condições bucais maternas e de saúde do recém-nascido. Material e método Realizou-se um estudo transversal com puérperas identificadas em uma maternidade no estado de Minas Gerais, em que foram coletados dados de atenção odontológica durante a gestação, condições de saúde bucal materna, Índice de Apgar do recém-nascido e variáveis de confundimento. Os dados foram analisados inicialmente de forma descritiva e a correlação entre a atenção odontológica e o Índice de Apgar foi testada por meio do teste de Pearson. Resultado Foram analisados os dados coletados das 144 puérperas e seus bebês, mas não foram encontradas correlações entre o Índice de Apgar e nenhuma das variáveis de cuidado odontológico, variáveis maternas e do recém-nascido coletadas no estudo. Conclusão Não foram observadas correlações do Índice de Apgar com nenhuma variável de cuidado odontológico, variáveis maternas e do recém-nascido. recémnascido. recémnascido recém nascido. nascido Realizouse Realizou se Gerais gestação materna confundimento Pearson 14 bebês odontológico 1

Abstract Aim To verify the existence of a relationship between dental care for pregnant women and maternal oral conditions and the health of the newborn. Material and method A cross-sectional study was carried out with mothers identified in a maternity hospital in the state of Minas Gerais, in which data on dental care during pregnancy, maternal oral health conditions, Apgar score of the newborn and confounding variables were collected. The data were initially analyzed descriptively and the adaptation between dental care and the Apgar score was tested using the Pearson test. Result Data collected from 144 postpartum women and their babies were analyzed, but no correlations were found between the Apgar score and any of the dental care, maternal and newborn variables collected in the study. Conclusion No correlations of the Apgar Score with any dental care variables, maternal and newborn variables were observed. crosssectional cross sectional Gerais pregnancy test 14 observed 1

https://doi.org/10.1590/1807-2577.00624

Effect of photobiomodulation therapy on pain perception during anesthetic puncture of dental local anesthesia: A systematic review anesthesia
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Mesquita, Caio Melo

; Oliveira, Millena Barroso

; Costa, Marcelo Dias Moreira de Assis

; Vieira, Walbert Andrade

; Lima, Rafael Rodrigues

; Rode, Sigmar de Mello

; Paranhos, Luiz Renato

Clinics

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2024, Volume 79 elocation 100322

Resumo: En | Texto: En | PDF: En

Abstract Background Local anesthetic puncture is often related to the experience of pain. This study aimed to systematically analyze the literature on changes in pain perception during the anesthetic puncture of dental local anesthesia after Photobiomodulation Therapy (PBMT). Material and methods An electronic search was performed in eight primary databases (Embase, LILACS, BBO, LIVIVO, MedLine via PubMed, SciELO, Scopus, and Web of Science) and three additional ones (EASY, Google Scholar, and OATD) to partially capture the “gray literature”. The PICO strategy was used to identify randomized clinical trials evaluating the analgesic effect of PBMT in the anesthetic puncture site of dental local anesthesia compared to placebo or control groups, without restrictions on publication language and year. Two reviewers extracted the data and assessed the individual risk of bias of the eligible studies using the Cochrane Collaboration Risk of Bias Tool version 2.0. Results The electronic search found 3,485 records, of which eight met the eligibility criteria and were included in the qualitative synthesis. The studies were published from 2011 to 2022. None of the included studies had a low risk of bias. PBMT groups showed no significant difference in pain scores compared to placebo and control groups of most studies. Conclusion Based on a low to very low certainty of evidence, PBMT seems to have no effect on pain perception during anesthetic puncture in patients undergoing dental local anesthesia. PBMT. . (PBMT) Embase, Embase (Embase LILACS BBO LIVIVO PubMed SciELO Scopus Science EASY, EASY (EASY Scholar OATD gray literature. literature” year 20 2 0 2.0 3485 3 485 3,48 records synthesis 201 2022 evidence (PBMT 2. 348 48 3,4 202 34 4 3,

https://doi.org/10.1016/j.clinsp.2023.100322

Nicodemo's method on dental development: a cross-sectional study with 3,271 children and adolescents Nicodemos Nicodemo s development crosssectional cross sectional 3271 3 271 3,27 327 27 3,2 32 2 3,
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Valente, Raquel Porto Alegre

; Lima, Lorenna Keren Gomes

; Bueno, Juliano Martins

; Oliveira, Millena Barroso

; Franco, Ademir

; Paranhos, Luiz Renato

Brazilian Oral Research

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2024, Volume 38 elocation e109

Resumo: En | Texto: En | PDF: En

Abstract Civil and criminal forensics utilize dental development to estimate age. The method of Nicodemo, Moraes, and Médici Filho (NMM) is a popular dental age estimation tool in South America; however, it lacks a scientific basis for applications in contemporary forensic practice. This research included the largest sample ever collected in Brazil for a similar purpose. The sample consisted of 3,271 panoramic radiographs of female (n = 1,634) and male (n = 1,637) individuals between six and 22.9 years old (mean 14.6 ± 4.9 years). The applied NMM method considered all maxillary and mandibular left permanent teeth (n = 16). The fit between the chronological age and estimated age intervals was assessed, and a correlation test with Lin's correlation coefficient was performed. The overall percentage of fit was 22.5%, without statistically significant differences based on sex (p > 0.05). The percentage of fit was greater in younger individuals, such as those aged 6–6.99 years (90%), and progressively decreased in older individuals, such as those aged 11–11.9 years (18.2%). After 12 years of age, the method could not provide correct classifications up to 25 years of age. Lin's correlation coefficient was predominantly low (ρ = 0.175; 0.367). NMM is considerably limited, and current forensic practice should not apply it to estimate dental age. Nicodemo Moraes (NMM America however purpose 3271 3 271 3,27 n 1,634 1634 1 634 1,637 1637 637 229 22 9 22. mean 146 14 6 14. 49 4 4. years. . years) 16. 16 16) assessed Lins Lin s performed 225 5 22.5% p 0.05. 005 0.05 0 05 0.05) 6699 99 6–6.9 90%, 90 90% , (90%) 11119 11 11–11. 18.2%. 182 18.2% 18 2 (18.2%) ρ 0.175 0175 175 0.367. 0367 0.367 367 0.367) limited 327 27 3,2 1,63 163 63 22.5 00 0.0 669 6–6. (90% 1111 11–11 18.2 (18.2% 0.17 017 17 036 0.36 36 32 3, 1,6 0. 66 6–6 (90 111 11–1 18. (18.2 0.1 01 03 0.3 1, 6– (9 11– (18. ( (18 (1

https://doi.org/10.1590/1807-3107bor-2024.vol38.0109

Antimicrobial efficacy of natural-based endodontic solutions: a systematic review with a network meta-analysis naturalbased natural based solutions metaanalysis meta analysis
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FERRAZ, Danilo Cassiano

; MELO, Anahi de Paula

; MATOS, Felipe de Souza

; PARANHOS, Luiz Renato

; MOURA, Camilla Christian Gomes

; BLUMENBERG, Cauane

; GUERREIRO-TANOMARU, Juliane Maria

; TANOMARU-FILHO, Mário

Brazilian Oral Research

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2024, Volume 38 elocation e093

Resumo: En | Texto: En | PDF: En

Abstract This systematic review aims to provide preclinical evidence of the antimicrobial efficacy of natural endodontic solutions (NES) compared to sodium hypochlorite (NaOCl) and chlorhexidine (CHX) against Enterococcus faecalis. The study followed the PRISMA guidelines and had a registered protocol (PROSPERO – CRD42021224022). The inclusion criteria comprised ex vivo studies simulating root canal irrigation to assess the standardized mean difference of colony-forming units (CFUs). Records were systematically identified in PubMed, Scopus, EMBASE, SciELO, Web of Science, LILACS, DANS Easy, and BDTD databases in January 2024. The RoBDEMAT tool helped determine the risk of bias. As for the network meta-analysis, CFU data were collected pre- and post-irrigation protocols as an effect measure. Thirty-five studies met the eligibility criteria and were included in the qualitative analysis, and seven studies were eligible for the network meta-analysis. The total sample consisted of 1,504 root canals. Among the tested solutions, apple cider vinegar combined with 2.5% NaOCl showed the highest probability of reducing CFUs after root canal irrigation (95%CI: -0.76–0.20), followed by 2% CHX and NaOCl (considering the different concentrations [95%CI: -0.32–0.17]). The bias assessment revealed significant omissions in reporting, particularly regarding sample size calculation, sample randomization, and operator blinding. The obtained evidence demonstrated that, even though NES did not overcome NaOCl, they have antimicrobial potential against Enterococcus faecalis. (NES (NaOCl (CHX faecalis PROSPERO CRD42021224022. CRD42021224022 CRD . CRD42021224022) colonyforming colony forming CFUs. (CFUs) PubMed Scopus EMBASE SciELO Science LILACS Easy 2024 metaanalysis, metaanalysis meta analysis meta-analysis pre postirrigation post measure Thirtyfive Thirty five metaanalysis. analysis. 1504 1 504 1,50 canals 25 2 5 2.5 95%CI 95CI CI 95 (95%CI 0.76–0.20, 076020 0.76–0.20 , 0 76 20 -0.76–0.20) considering [95%CI 0.32–0.17. 032017 0.32–0.17 32 17 -0.32–0.17]) reporting calculation randomization blinding that CRD4202122402 (CFUs 202 150 50 1,5 2. 9 07602 0.76–0.2 7 -0.76–0.20 03201 0.32–0.1 3 -0.32–0.17] CRD420212240 15 1, 0760 0.76–0. -0.76–0.2 0320 0.32–0. -0.32–0.17 CRD42021224 076 0.76–0 -0.76–0. 032 0.32–0 -0.32–0.1 CRD4202122 07 0.76– -0.76–0 03 0.32– -0.32–0. CRD420212 0.76 -0.76– 0.32 -0.32–0 CRD42021 0.7 -0.76 0.3 -0.32– CRD4202 0. -0.7 -0.32 CRD420 -0. -0.3 CRD42 -0 CRD4 -

https://doi.org/10.1590/1807-3107bor-2024.vol38.0093

Changes in salivary biomarkers of pain, anxiety, stress, and inflammation related to tooth movement during orthodontic treatment: a systematic review pain anxiety stress treatment
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RODRIGUES, Rodrigo

; MESQUITA, Caio Melo

; ALVES, Helena Benatt do Nascimento

; SILVA, Filipe Gontijo

; VIEIRA, Walbert de Andrade

; AGUIAR, Paula Cristiana Santos de

; FLORES-MIR, Carlos

; PARANHOS, Luiz Renato

; BRITO-JÚNIOR, Rui Barbosa de

Dental Press Journal of Orthodontics

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2024, Volume 29 Nº 6 elocation e242436

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Esta revisão sistemática teve como objetivo analisar a literatura sobre alterações em biomarcadores salivares endógenos de dor, ansiedade, estresse e inflamação relacionados à movimentação dentária durante tratamento ortodôntico de crianças e adolescentes. Material e Métodos: Foram realizadas buscas eletrônicas em nove bases de dados para identificar estudos quase-experimentais sobre o tema, sem restrições de idioma e ano de publicação. Dois revisores extraíram os dados e avaliaram o risco individual de viés usando as ferramentas JBI, e a certeza da evidência usando a ferramenta GRADE. Resultados: A busca eletrônica encontrou 7.038 registros, dos quais 12 atenderam aos critérios de elegibilidade e foram incluídos na síntese qualitativa. A maioria dos estudos apresentou baixo risco de viés. Os biomarcadores foram agrupados em cinco categorias: eletrólitos, enzimas, hormônios, imunoglobulinas e mediadores. Os eletrólitos apresentaram diminuição dos níveis de Ca2+, Pi3+ e K+ e aumento dos níveis de Na+ e Cl-. Todas as enzimas (ALP, LDH, MMP8 e MMP9) aumentaram ao longo do tempo. Os hormônios apresentaram diminuição da leptina e algumas oscilações nos níveis diários de cortisol. As imunoglobulinas (IgA, IgG, IgM, IgD e IgE) não tiveram alterações significativas, e a IgA salivar apresentou resultados divergentes entre os estudos. Os mediadores (sRANKL, OPG, IL-1β e PGE2) apresentaram flutuações nas diferentes fases do tratamento, principalmente após a ativação ortodôntica. Conclusões: Com base em um nível de certeza muito baixo, a movimentação dentária ortodôntica teve pouco ou nenhum efeito sobre biomarcadores salivares endógenos. Objetivo dor ansiedade adolescentes Métodos quaseexperimentais quase experimentais tema publicação JBI GRADE Resultados 7038 7 038 7.03 registros 1 qualitativa categorias Ca2 Ca Ca2+ Pi3 Pi K Na Cl. Cl . Cl- ALP, ALP (ALP LDH MMP MMP9 tempo cortisol IgA, (IgA IgG IgM IgE significativas sRANKL, sRANKL (sRANKL OPG IL1β ILβ IL 1β β PGE2 PGE Conclusões 703 03 7.0 70 0 7.

ABSTRACT Objective: This systematic review aimed to analyze the literature on changes in endogenous salivary biomarkers of pain, anxiety, stress, and inflammation related to tooth movement during orthodontic treatment of children and adolescents. Material and Methods: An electronic search was performed in nine databases to identify quasi-experimental studies, without restricting publication language and year. Two reviewers extracted the data and assessed the individual risk of bias using the JBI tools, and the certainty of evidence using the GRADE tool. Results: The electronic search found 7,038 records, of which 12 met the eligibility criteria and were included in the qualitative synthesis. Most studies had a low risk of bias. Biomarkers were grouped into five categories: electrolytes, enzymes, hormones, immunoglobulins, and mediators. Electrolytes showed decreased Ca2+, Pi3+ and K+ levels, and increased Na+ and Cl- levels. All enzymes (ALP, LDH, MMP8, and MMP9) increased over time. Hormones presented a decrease in leptin and some fluctuations in daily cortisol levels. Immunoglobulins (IgA, IgG, IgM, IgD, and IgE) had no significant changes, and salivary IgA showed divergent results among studies. Mediators (sRANKL, OPG, IL‐1β, and PGE2) showed fluctuations at different treatment stages, mainly after orthodontic activation. Conclusions: Based on a very low certainty level, orthodontic tooth movement had little to no effect on endogenous salivary biomarkers. Objective pain anxiety stress adolescents Methods quasiexperimental quasi experimental year tools tool Results 7038 7 038 7,03 records 1 synthesis categories electrolytes hormones immunoglobulins mediators Ca2 Ca Ca2+ Pi3 Pi K levels Na Cl ALP, ALP (ALP LDH MMP8 MMP MMP9 time IgA, (IgA IgG IgM IgD IgE sRANKL, sRANKL (sRANKL OPG IL1β ILβ IL 1β β IL‐1β PGE2 PGE stages activation Conclusions level 703 03 7,0 70 0 7,

https://doi.org/10.1590/2177-6709.29.6.e242436.oar

Perception of malocclusion and school performance in adolescents: a systematic review adolescents
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COSTA, Ana Carla Souza

; PAULO, Djessyca Miranda e

; VIDIGAL, Maria Tereza Campos

; VIEIRA, Walbert de Andrade

; CARDENAS, Andres Felipe Millan

; PARANHOS, Luiz Renato

Brazilian Oral Research

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2023, Volume 37 elocation e033

Resumo: En | Texto: En | PDF: En

Abstract This study aimed to assess the potential association between perception malocclusion and school performance in children and adolescents. An electronic search was performed in ten databases. Based on the PECO acronym (Population, Exposition, Comparator, and Outcome), the eligibility criteria included observational studies that compared the school performance of children and adolescents with and without the perception of malocclusion. There were no restrictions on the language or year of publication. Two reviewers selected the studies, extracted the data, and assessed the risk of bias by using the Joanna Briggs Institute tool for cross-sectional studies. School performance was measured by analyzing student grades; levels of absenteeism; and child or adolescent self-perception and/or the perception of parents, guardians, close friends, and teachers regarding the impact of malocclusion on school performance. The data were described narratively/descriptively. The search resulted in 3,581 registers, of which eight were included in the qualitative synthesis. These studies were published between 2007 and 2021. Two studies concluded that there was no significant association between school performance and perception of malocclusion, five studies found that only some of the children with malocclusion had their school performance affected, and one study concluded that there was a significant association between perception of malocclusion and low school performance. Considering all variables and the very low certainty of evidence, the perception of malocclusion seems to negatively impact school performance when associated with external and subjective factors. Further studies using additional measurement standards are required. databases Population, Population (Population Exposition Comparator Outcome, Outcome , Outcome) publication crosssectional cross sectional grades absenteeism selfperception self andor parents guardians friends narrativelydescriptively narratively descriptively narratively/descriptively 3581 3 581 3,58 registers synthesis 200 2021 affected evidence factors required 358 58 3,5 20 202 35 5 3, 2

https://doi.org/10.1590/1807-3107bor-2023.vol37.0033

10.

Efficacy, safety, and potential industry bias in using deoxycholic acid for submental fat reduction - A systematic review and meta-analysis of randomized clinical trials Efficacy safety metaanalysis meta analysis
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Inocencio, Gabriel Santiago Giuglio

; Meneses-Santos, Daniela

; Costa, Marcelo Dias Moreira de Assis

; Vieira, Walbert A.

; Almeida, Vinicius Lima de

; Rodrigues, Renata Prata Cunha Bernardes

; Rode, Sigmar de Mello

; Paranhos, Luiz Renato

Clinics

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2023, Volume 78 elocation 100220

Resumo: En | Texto: En | PDF: En

Abstract Lipolytic substance injections to reduce localized fat have been extensively used because it is a low-invasive method. This review aimed to evaluate the efficacy and safety of deoxycholic acid in submental fat reduction compared to a placebo and investigate the potential industry sponsorship bias in the results of randomized clinical trials on this topic. Ten electronic databases were extensively searched for randomized clinical trials without restriction on language and year of publication. Two reviewers extracted the data and assessed the individual risk of bias in the studies with the RoB 2.0 tool. The industry sponsorship bias was evaluated according to citations in the articles regarding industry funding/sponsorship throughout the texts. Fixed and random effects meta-analyses were performed, and the results were reported in Risk Ratio (RR) at a 95% Confidence Interval (95% CI). The initial search provided 5756 results, of which only five were included. Only two studies had a low risk of bias. All studies showed a potential industry bias. The meta-analysis showed that patients treated with deoxycholic acid had significant positive results for all efficacy outcomes and a higher risk of fibrosis, pain, erythema, numbness, swelling, edema, pruritus, nodules, headache, and paresthesia. The low to moderate certainty of evidence found allows concluding that deoxycholic acid is effective in submental fat reduction, causing well-tolerated adverse effects. However, all eligible studies showed a potential industry bias. lowinvasive invasive method topic publication 20 2 0 2. tool fundingsponsorship funding texts metaanalyses meta analyses performed RR (RR 95 (95 CI. CI . CI) 575 included metaanalysis analysis fibrosis pain erythema numbness swelling edema pruritus nodules headache paresthesia welltolerated well tolerated However 9 (9 57 ( 5

https://doi.org/10.1016/j.clinsp.2023.100220

11.

Association of salivary alpha-2-macroglobulin with glycemia and glycated hemoglobin in type 2 diabetes mellitus: a systematic review and meta-analysis study
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Caixeta, Douglas Carvalho

; Pennisi, Pedro Rogério Camargos

; Moura, Douglas Vieira

; Nunes, Marjorie Adriane Costa

; Espindola, Foued Salmen

; Blumenberg, Cauane

; Paranhos, Luiz Renato

; Sabino-Silva, Robinson

Sao Paulo Medical Journal

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Dez 2022, Volume 140 Nº 6 Páginas 818 - 828

Resumo: En | Texto: En | PDF: En

Abstract BACKGROUND: Chronically elevated alpha-2-macroglobulin (A2MG) in the blood has been correlated with diabetes and the HbA1c profile; however, no systematic review has been conducted to evaluate the association of A2MG salivary levels and glycemia or HbA1c levels in diabetes mellitus type 2 (DM2) patients. OBJECTIVE: To evaluate whether A2MG salivary levels are related to the glycemia or HbA1c levels in DM2 patients. DESIGN AND SETTING: Systematic review developed at Universidade Federal de Uberlândia (UFU), Brazil. METHODS: Eight databases were used as research sources. The eligibility criteria included studies that reported data regarding mean salivary A2MG and the correlation between glycemia and/or HbA1c levels of DM2 subjects (uncontrolled and well-controlled) and non-diabetic subjects. The risk of bias of the studies selected was assessed using the Joanna Briggs Institute (JBI) critical appraisal tools for use in JBI systematic reviews. Pooled correlation coefficients were estimated using the Hunter-Schmidt method. Study estimates were weighted according to their sample size, and heterogeneity was calculated using the chi-square statistic. RESULTS: Four studies on DM2 patients were included in this systematic review after careful analysis of 1482 studies. Three studies compared A2MG with HbA1c and glycemia. Overall, the correlation between A2MG and HbA1c was strong (r = 0.838). In contrast, the correlation between A2MG and glycemia was low (r = 0.354). CONCLUSION: The strong association between HbA1C and salivary A2MG suggests that this salivary protein has the potential to be a surrogate for HbA1C, if corroboratory further evidence is obtained through large-scale studies.

https://doi.org/10.1590/1516-3180.2021.0816.r2.19052022

12.

IMPACTO-MR: um estudo brasileiro de plataforma nacional para avaliar infecções e multirresistência em unidades de terapia intensiva IMPACTOMR IMPACTO MR IMPACTO-MR
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Tomazini, Bruno M

; Nassar Jr, Antonio Paulo

; Lisboa, Thiago Costa

; Azevedo, Luciano César Pontes de

; Veiga, Viviane Cordeiro

; Catarino, Daniela Ghidetti Mangas

; Fogazzi, Debora Vacaro

; Arns, Beatriz

; Piastrelli, Filipe Teixeira

; Dietrich, Camila

; Negrelli, Karina Leal

; Jesuíno, Isabella de Andrade

; Reis, Luiz Fernando Lima

; Mattos, Renata Rodrigues de

; Pinheiro, Carla Cristina Gomes

; Luz, Mariane Nascimento

; Spadoni, Clayse Carla da Silva

; Moro, Elisângela Emilene

; Bueno, Flávia Regina

; Sampaio, Camila Santana Justo Cintra

; Silva, Débora Patrício

; Baldassare, Franca Pellison

; Silva, Ana Cecilia Alcantara

; Veiga, Thabata

; Barbante, Leticia

; Lambauer, Marianne

; Campos, Viviane Bezerra

; Santos, Elton

; Santos, Renato Hideo Nakawaga

; Laranjeiras, Ligia Nasi

; Valeis, Nanci

; Santucci, Eliana

; Miranda, Tamiris Abait

; Patrocínio, Ana Cristina Lagoeiro do

; Carvalho, Andréa de

; Sousa, Eduvirgens Maria Couto de

; Sousa, Ancelmo Honorato Ferraz de

; Malheiro, Daniel Tavares

; Bezerra, Isabella Lott

; Rodrigues, Mirian Batista

; Malicia, Julliana Chicuta

; Silva, Sabrina Souza da

; Gimenes, Bruna dos Passos

; Sesin, Guilhermo Prates

; Zavascki, Alexandre Prehn

; Sganzerla, Daniel

; Medeiros, Gregory Saraiva

; Santos, Rosa da Rosa Minho dos

; Silva, Fernanda Kelly Romeiro

; Cheno, Maysa Yukari

; Abrahão, Carolinne Ferreira

; Oliveira Junior, Haliton Alves de

; Rocha, Leonardo Lima

; Nunes Neto, Pedro Aniceto

; Pereira, Valéria Chagas

; Paciência, Luis Eduardo Miranda

; Bueno, Elaine Silva

; Caser, Eliana Bernadete

; Ribeiro, Larissa Zuqui

; Fernandes, Caio Cesar Ferreira

; Garcia, Juliana Mazzei

; Silva, Vanildes de Fátima Fernandes

; Santos, Alisson Junior dos

; Machado, Flávia Ribeiro

; Souza, Maria Aparecida de

; Ferronato, Bianca Ramos

; Urbano, Hugo Corrêa de Andrade

; Moreira, Danielle Conceição Aparecida

; Souza-Dantas, Vicente Cés de

; Duarte, Diego Meireles

; Coelho, Juliana

; Figueiredo, Rodrigo Cruvinel

; Foreque, Fernanda

; Romano, Thiago Gomes

; Cubos, Daniel

; Spirale, Vladimir Miguel

; Nogueira, Roberta Schiavon

; Maia, Israel Silva

; Zandonai, Cassio Luis

; Lovato, Wilson José

; Cerantola, Rodrigo Barbosa

; Toledo, Tatiana Gozzi Pancev

; Tomba, Pablo Oscar

; Almeida, Joyce Ramos de

; Sanches, Luciana Coelho

; Pierini, Leticia

; Cunha, Mariana

; Sousa, Michelle Tereza

; Azevedo, Bruna

; Dal-Pizzol, Felipe

; Damasio, Danusa de Castro

; Bainy, Marina Peres

; Beduhn, Dagoberta Alves Vieira

; Jatobá, Joana D’Arc Vila Nova

; Moura, Maria Tereza Farias de

; Rego, Leila Rezegue de Moraes

; Silva, Adria Vanessa da

; Oliveira, Luana Pontes

; Sodré Filho, Eliene Sá

; Santos, Silvana Soares dos

; Neves, Itallo de Lima

; Leão, Vanessa Cristina de Aquino

; Paes, João Lucidio Lobato

; Silva, Marielle Cristina Mendes

; Oliveira, Cláudio Dornas de

; Santiago, Raquel Caldeira Brant

; Paranhos, Jorge Luiz da Rocha

; Wiermann, Iany Grinezia da Silva

; Pedroso, Durval Ferreira Fonseca

; Sawada, Priscilla Yoshiko

; Prestes, Rejane Martins

; Nascimento, Glícia Cardoso

; Grion, Cintia Magalhães Carvalho

; Carrilho, Claudia Maria Dantas de Maio

; Dantas, Roberta Lacerda Almeida de Miranda

; Silva, Eliane Pereira

; Silva, Antônio Carlos da

; Oliveira, Sheila Mara Bezerra de

; Golin, Nicole Alberti

; Tregnago, Rogerio

; Lima, Valéria Paes

; Silva, Kamilla Grasielle Nunes da

; Boschi, Emerson

; Buffon, Viviane

; Machado, André Sant’Ana

; Capeletti, Leticia

; Foernges, Rafael Botelho

; Carvalho, Andréia Schubert de

; Oliveira Junior, Lúcio Couto de

; Oliveira, Daniela Cunha de

; Silva, Everton Macêdo

; Ribeiro, Julival

; Pereira, Francielle Constantino

; Salgado, Fernanda Borges

; Deutschendorf, Caroline

; Silva, Cristofer Farias da

; Gobatto, Andre Luiz Nunes

; Oliveira, Carolaine Bomfim de

; Dracoulakis, Marianna Deway Andrade

; Alvaia, Natália Oliveira Santos

; Souza, Roberta Machado de

; Araújo, Larissa Liz Cardoso de

; Melo, Rodrigo Morel Vieira de

; Passos, Luiz Carlos Santana

; Vidal, Claudia Fernanda de Lacerda

; Rodrigues, Fernanda Lopes de Albuquerque

; Kurtz, Pedro

; Shinotsuka, Cássia Righy

; Tavares, Maria Brandão

; Santana, Igor das Virgens

; Gavinho, Luciana Macedo da Silva

; Nascimento, Alaís Brito

; Pereira, Adriano J

; Cavalcanti, Alexandre Biasi

Revista Brasileira de Terapia Intensiva

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Dez 2022, Volume 34 Nº 4 Páginas 418 - 425

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Descrever o IMPACTO-MR, um estudo brasileiro de plataforma nacional em unidades de terapia intensiva focado no impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Métodos: Descrevemos a plataforma IMPACTO-MR, seu desenvolvimento, critérios para seleção das unidades de terapia intensiva, caracterização da coleta de dados, objetivos e projetos de pesquisa futuros a serem realizados na plataforma. Resultados: Os dados principais foram coletados por meio do Epimed Monitor System® e consistiram em dados demográficos, dados de comorbidades, estado funcional, escores clínicos, diagnóstico de internação e diagnósticos secundários, dados laboratoriais, clínicos e microbiológicos e suporte de órgãos durante a internação na unidade de terapia intensiva, entre outros. De outubro de 2019 a dezembro de 2020, 33.983 pacientes de 51 unidades de terapia intensiva foram incluídos no banco de dados principal. Conclusão: A plataforma IMPACTO-MR é um banco de dados clínico brasileiro de unidades de terapia intensiva focado na pesquisa do impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Essa plataforma fornece dados para o desenvolvimento e pesquisa de unidades de terapia intensiva individuais e ensaios clínicos observacionais e prospectivos multicêntricos. Objetivo IMPACTOMR, IMPACTOMR IMPACTO MR, MR saúde Métodos Resultados System demográficos comorbidades funcional secundários laboratoriais outros 201 2020 33983 33 983 33.98 5 principal Conclusão multicêntricos 20 202 3398 3 98 33.9 2 339 9 33.

ABSTRACT Objective: To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on the impact of health care-associated infections due to multidrug-resistant bacteria. Methods: We described the IMPACTO-MR platform, its development, criteria for intensive care unit selection, characterization of core data collection, objectives, and future research projects to be held within the platform. Results: The core data were collected using the Epimed Monitor System® and consisted of demographic data, comorbidity data, functional status, clinical scores, admission diagnosis and secondary diagnoses, laboratory, clinical, and microbiological data, and organ support during intensive care unit stay, among others. From October 2019 to December 2020, 33,983 patients from 51 intensive care units were included in the core database. Conclusion: The IMPACTO-MR platform is a nationwide Brazilian intensive care unit clinical database focused on researching the impact of health care-associated infections due to multidrug-resistant bacteria. This platform provides data for individual intensive care unit development and research and multicenter observational and prospective trials. Objective IMPACTOMR, IMPACTOMR IMPACTO MR, MR careassociated associated multidrugresistant multidrug resistant bacteria Methods selection collection objectives Results System status scores diagnoses laboratory stay others 201 2020 33983 33 983 33,98 5 Conclusion trials 20 202 3398 3 98 33,9 2 339 9 33,

https://doi.org/10.5935/0103-507x.20220209-pt

13.

Use of platelet-rich fibrin for bone repair: a systematic review and meta-analysis of preclinical studies
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REIS, Nayara Teixeira de Araújo

; João Lucas Carvalho, PAZ

; PARANHOS, Luiz Renato

; BERNARDINO, Ítalo de Macedo

; MOURA, Camilla Christian Gomes

; IRIE, Milena Suemi

; SOARES, Priscilla Barbosa Ferreira

Brazilian Oral Research

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2022, Volume 36 elocation e129

Resumo: En | Texto: En | PDF: En

Abstract This systematic review evaluated the potential utility of platelet-rich fibrin (PRF) in bone repair in animals. The question is: can the use of PRF in bone defects in healthy rats induce bone repair compared to clot? This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (Prisma). The protocol was registered with Prospero (CRD [42020162319]). The literature search involved nine databases, including grey literature. All studies evaluated the bone defects created in rats filled with PRF and clots (control). Biomaterial evaluation was also performed in this study. The risk of bias was assessed using the Systematic Review Center for Laboratory Animal Experimentation (Syrcle) tool for animal studies. A meta-analysis of quantitative data was performed to estimate the effect of PRF on bone repair in rats. Heterogeneity among the studies was assessed using the I2 statistic. The literature search retrieved 685 studies, 10 of which fulfilled the eligibility criteria, and 4 were included in the quantitative assessment. Analysis of the risk of bias revealed that most studies had a high risk of bias in performance and detection. Meta-analysis yielded divergent results and the absence of a statistically significant effect: PRF with control (standardized mean difference 2.54, 95% confidence interval -0.80–5.89; p = 0.14). In general, study heterogeneity was high (I2 ≥ 75.0%). The quality of the studies that influenced the conclusion of the review was based on the PICO, the sources and form of the search, the study selection criteria, the form of evaluation of publication bias, the evaluation of the quality of the studies, and data extraction by two researchers. PRF did not provide significant benefits for bone repair, resulting in unpredictable effects.

https://doi.org/10.1590/1807-3107bor-2022.vol36.0129

14.

Analysis of financial resources for public health in Brazilian capitals: a time trend ecological study
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Oliveira, Vinícius Henrique Ferreira Pereira de

; Oliveira, Millena Barroso

; Blumenberg, Cauane

; Herval, Álex Moreira

; Paranhos, Luiz Renato

Cadernos de Saúde Pública

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2022, Volume 38 Nº 1 elocation e00311620

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

O estudo teve como objetivo analisar parte dos recursos utilizados para financiar ações de saúde pública nas 26 capitais brasileiras entre 2008 e 2018. O estudo ecológico de tendências temporais envolveu indicadores de receitas e gastos fornecidos pelo Sistema de Informação sobre Orçamento Público em Saúde (SIOPS). Os valores foram deflacionados com base no Índice de Preços ao Consumidor Amplo de 2018 no Brasil para permitir a comparação ao longo dos anos. A variação anual média dos investimentos em saúde, em Reais (BRL), foi avaliada com o uso de regressões lineares. Os coeficientes de correlação de Pearson foram estimados entre as receitas e gastos federais com os recursos das capitais. Todas as capitais apresentaram correlações estatisticamente positivas com a origem do recurso orçamentário investido em saúde. O menor coeficiente foi encontrado na cidade de Macapá (Amapá) (r = 0,860), e o mais alto em Fortaleza (Ceará) (r = 0.997). Belo Horizonte (Minas Gerais) foi a capital com o maior aumento anual em transferências federais (cerca de BRL 67,91 por ano) e Teresina (Piauí) apresentou o maior aumento anual nos gastos em saúde (cerca de BRL 55,42 por ano). Houve um aumento real nas transferências no Sistema Único de Saúde (SUS) e nos recursos municipais em quase todas as capitais, mas ainda persistem desigualdades na distribuição dos recursos financeiros entre as capitais brasileiras das cinco regiões. O financiamento da saúde é afetado pela municipalização do SUS, e não é o único fator que afeta o acesso e a qualidade dos serviços de saúde.

This study aimed to analyze part of the financial resources used to fund public health actions in the 26-Brazilian capitals, from 2008 to 2018. This is a time-trend ecological study involving revenue and expenditure indicators provided by the Information System on Public Budget for Health (SIOPS). The values were deflated based on the Extended National Consumer Price Index of 2018 in Brazil to allow the comparison over the years. The mean annual variation of health investments, in Brazilian Reais (BRL) was assessed using linear regressions. Pearson’s correlation coefficients were estimated between federal revenues and expenditures with the capitals’ resources. All capitals presented statistically significant positive correlations for the origin of the budget resource invested in health. The lowest coefficient was found in the capital city of Macapá (Amapá State) (r = 0.860) and the highest, in Fortaleza (Ceará State) (r = 0.997). Belo Horizonte (Minas Gerais State) was the capital with the highest annual increase in federal transfers (about BRL 67.91 per year) and Teresina (Piauí State) presented the highest annual increase in health expenditures among the capitals (about BRL 55.42 per year). We found a increase in the transfers of the Brazilian Unified National Health System (SUS) and municipal resources in almost all capitals, but there are still inequalities in the distribution of financial resources among Brazilian capitals from different regions. Health funding is affected by the municipalization of SUS and it is not the single factor affecting the access and quality of health services.

El objetivo fue analizar la parte de recursos financieros utilizados para financiar acciones de salud públicas en 26 capitales brasileñas, entre 2008 y 2018. Se trata de un estudio ecológico de tendencia temporal, implicando indicadores de ingresos y gastos proporcionados por el Sistema de Información sobre el Presupuesto Público para Salud (SIOPS). Se deflactaron los valores basados en el Índice de Precios al Consumidor, ampliado de 2018 en Brasil, para permitir la comparación a lo largo de los años. La variación anual media de inversiones en salud, en Reales brasileños (BRL), fue evaluada usando regresiones lineales. Se estimaron los coeficientes de correlación de Pearson entre los ingresos y gastos federales, respecto a los recursos de las capitales. Todas las capitales presentaron estadísticamente correlaciones positivas significativas respecto a la fuente presupuestaria originaria invertida en salud. El coeficiente más bajo se encontró en la capital de Macapá (Amapá) (r = 0.860) y el más alto en Fortaleza (Ceará) (r = 0.997). Belo Horizonte (Minas Gerais) fue la capital con el incremento anual más alto en transferencias federales (cerca de BRL 67.91 por año) y Teresina (Piauí) presentó el incremento anual más alto en gastos de salud entre todas las capitales (sobre BRL 55.42 por año). Hubo un incremento real de transferencias en el Sistema Único de Salud brasileño (SUS), así como recursos municipales en casi todas las capitales, pero existen todavía inequidades en la distribución de recursos financieros entre las capitales brasileñas de diferentes regiones. La financiación de la salud está afectada por la municipalización del SUS, y no es el único factor que afecta al acceso y calidad de los servicios de salud.

https://doi.org/10.1590/0102-311x00311620

15.

Ozone disinfection for viruses with applications in healthcare environments: a scoping review
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IRIE, Milena Suemi

; DIETRICH, Lia

; SOUZA, Gabriela Leite de

; SOARES, Priscilla Barbosa Ferreira

; MOURA, Camilla Christian Gomes

; SILVA, Gisele Rodrigues da

; PARANHOS, Luiz Renato

Brazilian Oral Research

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2022, Volume 36 elocation e006

Resumo: En | Texto: En | PDF: En

Abstract The aim of this scoping review was to provide sufficient information about the effectiveness of ozone gas in virus inactivation of surfaces and objects under different environmental conditions. The review was performed according to the list of PRISMA SrC recommendations and the JBI Manual for Evidence Synthesis for Scoping Reviews. The review was registered in Open Science Framework (OSF). EMBASE (Ovid), Lilacs, LIVIVO, MEDLINE (PubMed), SciELO, Scopus and Web of Science were primary sources, and “gray literature” was searched in OpenGray and OpenThesis. A study was included if it reported primary data on the effect of ozone gas application for vehicle-borne and airborne virus inactivation. No language or publication date restriction was applied. The search was conduct on July 1, 2020. A total of 16,120 studies were screened, and after exclusion of noneligible studies, fifteen studies fulfilled all selection criteria. Application of ozone gas varied in terms of concentration, ozone exposure period and the devices used to generate ozone gas. Twelve studies showed positive results for inactivation of different virus types, including bacteriophages, SARS-CoV-2 surrogates and other vehicle-borne viruses. Most of the studies were classified as unclear regarding sponsorship status. Although most of the population has not yet been vaccinated against COVID-19, disinfection of environments, surfaces, and objects is an essential prevention strategy to control the spread of this disease. The results of this Scoping Review demonstrate that ozone gas is promising for viral disinfection of surfaces.

https://doi.org/10.1590/1807-3107bor-2022.vol36.0006

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ti	título do artigo
au	autor
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subject	assunto (palavras do título, resumo e palavras-chave)
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journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

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