Resumo Do percurso de vida de Nuno Álvares Pereira foram sempre destacadas as ações guerreiras e as virtudes religiosas, permanecendo ainda nebuloso o seu desempenho como detentor de poderes jurisdicionais sobre vastos domínios. Quando as negociações de paz com Castela ficaram definitivamente encarreiradas e os seus serviços militares deixaram de ser indispensáveis à afirmação política de D. João I e à defesa do reino, Nuno Álvares Pereira, que, segundo é sabido, nunca se enraizou em nenhum lugar, parece centrar a sua atenção em Almada. Promoveu um paço no recinto do castelo, onde terá residido efetivamente, ainda que por um curto período, procedeu a investimentos, que motivaram o desacordo de D. João I, e interferiu na vida concelhia em diversas vertentes, ao abrigo dos seus poderes senhoriais. Foi ainda em Almada que tratou de assegurar a viabilização do empreendimento do convento do Carmo, para onde se retiraria em 1423, no ano seguinte à doação da vila e termo à neta Isabel.

Abstract From Nuno Álvares Pereira's life path, were always highlighted his warlike actions and his religious virtues, although his performance as holder of jurisdictional powers over vast domains still remains unclear. When peace negotiations with Castile were definitively in line and his military services were no longer indispensable to the political declaration of D. João I and the defense of the kingdom, Nuno Álvares Pereira, who, as is known, never took root in any place, seems to focus its attention on Almada. He promoted a palace in the castle grounds, where he effectively resided, albeit for a short period, and made investments, which led to the disagreement of D. João I, and interfered in the council's life in various aspects, under the protection of his manorial powers. It was also in Almada that he tried to ensure the viability of the Carmo convent, where he would retire in 1423, the year following the donation of the town and term to his granddaughter Isabel.

Abstract Susac’s Syndrome (SS) is an occlusive immune-mediated microangiopathy that preferentially affects cerebral, retinal and cochlear arterioles. Classically, it is associated with the triad of visual defects, encephalopathy and sensorineural hearing loss (SNH). Diagnosis is based on clinical features and findings from fluorescein angiography (FA), brain magnetic resonance imaging (CE-MRI) and audiometry. Treatment is based on high-dose corticosteroid therapy and must be started as soon as possible to prevent permanent sequelae. The clinical case presented is about a 34-year-old woman with multiple visits to the Emergency Department due to persistent headaches, psychomotor slowing and focal neurological deficits lasting 2 months. From the study carried out, multiple hyperintense lesions were found on T2 CE-MRI involving the corpus callosum, areas of retinal ischemia and hyperfluorescence on FA and bilateral moderate SNH at high frequencies on the audiogram. The diagnosis of SS was assumed and immunosuppressive therapy was started, maintaining clinical and audiometric surveillance.

Resumo A Síndrome de Susac (SS) é uma microangiopatia imunomediada oclusiva que atinge preferencialmente as arteríolas cerebrais, retinianas e cocleares. Classicamente, associa-se à tríade de defeitos visuais, encefalopatia e hipoacusia neurossensorial (HNS). O diagnóstico baseia-se na clínica e achados da angiografia fluoresceínica (AF), ressonância magnética cerebral (RMN-CE) e audiometria. O tratamento assenta na utilização de corticoterapia em altas doses e deve ser iniciado o mais precocemente possível para prevenir sequelas permanentes. O caso clínico apresentado é de uma mulher de 34 anos com múltiplas idas ao Serviço de Urgência por cefaleias persistentes, lentificação psicomotora e défices neurológicos focais com dois meses de evolução. Do estudo efetuado, foram constatadas múltiplas lesões hiperintensas na RMN-CE em T2 a envolver o corpo caloso, áreas de isquemia retiniana e hiperfluorescência na AF e HNS moderada bilateral nas frequências elevadas no audiograma. Assumiu-se o diagnóstico de SS e iniciou-se terapêutica imunossupressora, mantendo-se vigilância clínica e audiométrica.

ABSTRACT This study aimed to provide further insight into the evolutionary dynamics of SARS-CoV-2 by analyzing the case of a 40-year-old man who had previously undergone autologous hematopoietic stem cell transplantation due to a diffuse large B-cell lymphoma. He developed a persistent SARS-CoV-2 infection lasting at least 218 days and did not manifest a humoral immune response to the virus during this follow-up period. Whole-genome sequencing and viral cultures confirmed a persistent infection with a replication-positive virus that had undergone genetic variation for at least 196 days after symptom onset. SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- 40yearold yearold 40 year old Bcell B lymphoma 21 followup follow up period Wholegenome Whole genome replicationpositive replication positive 19 onset SARS-CoV 4 1

Resumo Neste ensaio examino as diferenças existentes entre o multiculturalismo e o interculturalismo assumindo que não somente representam modelos diferentes, como a sua institucionalização se situa a escalas distintas. Primeiro, ofereço um sistema de premissas para identificar o âmbito de uma prática ou política multicultural. Segundo, coloco em relevo os autores que entendem o interculturalismo como uma mera variação retórica do anterior multiculturalismo. Terceiro, procuro mostrar como podemos diferenciar os dois modelos partindo das suas lógicas institucionais. Finalmente, e com a brevidade de um ensaio, aponto algumas fragilidades ao multiculturalismo que tornam mais pertinente a crítica ensaiada pelos defensores do interculturalismo, bem assim como as suas principais propostas. Concluo salientando algumas premissas do interculturalismo onde se sustentam diferenças substantivas com o multiculturalismo.

Abstract In this essay, I examine the differences between multiculturalism and interculturalism assuming that not only they represent different models, but also their institutionalization occurs at different scales. First, I offer a system of premises to identify the scope of a multicultural practice or policy. Second, I highlight those authors who understand interculturalism as a mere rhetorical variation of earlier multiculturalism. Third, I try to show how we can differentiate the two models starting from their institutional logics. Finally, and with the brevity of an essay, I point out some weaknesses of multiculturalism that make the critique rehearsed by the defenders of interculturalism more pertinent, as well as their main proposals. I conclude by emphasizing some premises of interculturalism where substantive differences with multiculturalism are supported.

ABSTRACT Introduction: Optimal fluid balance in peritoneal dialysis requires adequate urinary and peritoneal water and sodium removal and restriction of dietary sodium intake (<2 g/day). We aim to study the relationship between sodium intake, blood pressure control and medication burden in peritoneal dialysis patients. Methods: Observational, cross-sectional study of chronic peritoneal dialysis patients followed in our hospital in March 2022. We estimated patient’s sodium intake according to the equations proposed by Kim et al. Mean ambulatory blood pressure was categorized in controlled, stage one, stage two and stage three hypertension. A qualitative evaluation of sodium intake was done by asking patients about their compliance with a low-salt diet. Results: Eighty-two patients: mostly men, with a mean age of 54.1±14.7 years and dialysis vintage of 26.2±18.7 months. Most patients were on continuous ambulatory peritoneal dialysis (63.4%) and the mean weekly Kt/V was 2.2±0.4. A percentage of 85.4% of our patients had residual diuresis, averaged at 1257±867 mL/day. Mean dietary sodium intake was 3.5±1.1 g; it was higher in men and patients with uncontrolled hypertension, regardless of age, dialysis vintage and other comorbidities. We found a strong correlation between dietary sodium intake and residual diuresis, systolic blood pressure, diastolic blood pressure and the number of anti-hypertensive drugs. Patients with a sodium intake ≥ 3.3 g had higher risk of uncontrolled BP and higher medication burden. Qualitative evaluation of this sub-population revealed that only 2.3% (n=1) admitted non-compliance with a low-sodium diet. Conclusion: We found a strong correlation between estimated dietary sodium consumption, blood pressure control and medication burden. Most importantly, there was a striking difference between patient’s perception of sodium consumption and the actual results. Our results highlight the importance of dietary salt restriction in blood pressure control and reinforce the need for a dietary consultation in peritoneal dialysis patients.

Abstract Introduction and objectives: Myofascial Pain Syndrome (MPS) of the Quadratus Lumborum muscle (QL) is a frequent cause of chronic low back pain. With this study, we aimed to assess the efficacy of ultrasound-guided infiltration with 0.25% levobupivacaine and 40 mg triamcinolone for MPS of the QL. Methods: Observational and retrospective study of participants submitted to ultrasound-guided infiltration of the QL muscle from January 1, 2015 to June 31, 2019. Pain intensity was assessed using the five-point pain Numeric Rating Scale (NRS): pre-intervention, at 72 hours, 1 month, 3 months and 6 months post-intervention. Additional data collected were demographic characteristics, opioid consumption, and adverse effects. Results: We assessed 90 participants with mean age of 55.2 years. Sixty-eight percent of participants were female. Compared to the pre-intervention assessment, there was an improvement in pain at 72 hours (Mean Difference [MD = 3.085]; 95% CI: 2.200-3.970, p < 0.05), at the 1st month (MD = 2.644; 95% CI: 1.667-3.621, p < 0.05), at the 3rdmonth (MD = 2.017; 95% CI: 0.202-2.729, p < 0.05) and at the 6th month (MD = 1.339; 95% CI 0.378-2.300, p < 0.05), post-intervention. No statistically significant differences in opioid consumption were observed. No adverse effects associated with the technique were reported. Conclusions: Ultrasound-guided infiltration of the QL muscle is a safe and effective procedure for the treatment of pain in the QL MPS within 6 months post-intervention. objectives (MPS (QL ultrasoundguided ultrasound guided 025 0 25 0.25 4 Methods 201 31 2019 fivepoint five point NRS (NRS) preintervention, preintervention pre intervention, intervention 7 postintervention. postintervention post intervention. post-intervention characteristics Results 9 552 55 2 55. years Sixtyeight Sixty eight female assessment Mean MD 3.085 3085 085 3.085] 95 2.2003.970, 22003970 2.200 3.970, 200 970 2.200-3.970 0.05, 005 0.05 , 05 st 2.644 2644 644 1.6673.621, 16673621 1.667 3.621, 667 621 1.667-3.621 rdmonth 2.017 2017 017 0.2022.729, 02022729 0.202 2.729, 202 729 0.202-2.729 th 1.339 1339 339 0.3782.300, 03782300 0.378 2.300, 378 300 0.378-2.300 observed reported Conclusions Ultrasoundguided Ultrasound 02 0.2 20 (NRS 5 3.08 308 08 2003 2.2003.970 2200397 2200 2.20 3970 3.970 97 2.200-3.97 00 0.0 2.64 264 64 6673 1.6673.621 1667362 1667 1.66 3621 3.621 66 62 1.667-3.62 2.01 01 2022 0.2022.729 0202272 0202 0.20 2729 2.729 0.202-2.72 1.33 133 33 3782 0.3782.300 0378230 0378 0.37 2300 2.300 37 30 0.378-2.30 0. 3.0 2.2003.97 220039 220 2.2 397 3.97 2.200-3.9 2.6 26 1.6673.62 166736 166 1.6 362 3.62 1.667-3.6 2.0 0.2022.72 020227 020 272 2.72 0.202-2.7 1.3 13 0.3782.30 037823 037 0.3 230 2.30 0.378-2.3 3. 2.2003.9 22003 22 2. 39 3.9 2.200-3. 1.6673.6 16673 16 1. 36 3.6 1.667-3. 0.2022.7 02022 27 2.7 0.202-2. 0.3782.3 03782 03 23 2.3 0.378-2. 2.2003. 2.200-3 1.6673. 1.667-3 0.2022. 0.202-2 0.3782. 0.378-2 2.2003 2.200- 1.6673 1.667- 0.2022 0.202- 0.3782 0.378-

Abstract Facial nerve schwannoma is a benign neoplasm originating from the Schwann cells of the facial nerve. It represents approximately 5% of facial paralysis cases and should be included in the differential diagnosis of peripheral facial paralysis. This neoplasm most frequently affects the tympanic and mastoid segments of the facial nerve. Therapeutic options include surgery, stereotactic radiosurgery or ’wait and scan’. We describe the case of a patient with an acute peripheral facial palsy, otalgia and left conduction hearing loss, that was interpreted as an acute otitis media complicated with facial paralysis based on the history, physical examination and imaging findings. Due to persistence the patient was submitted to an exploratory tympanomastoidectomy which confirmed the diagnosis of facial nerve schwannoma. During the procedure, a subtotal resection of the lesion was performed, which resulted in postoperative clinical and audiological improvement. After subtotal resection, we opted for regular observation and imaging evaluation of the tumor residue.

Resumo O schwannoma do nervo facial é uma neoplasia benigna com origem nas células de Schwann do nervo facial. Corresponde a cerca de 5% das paralisias faciais e deve ser incluído no diagnóstico diferencial de uma paralisia facial periférica. Esta neoplasia atinge mais frequentemente os segmentos timpânico e mastoideu do nervo facial. As opções terapêuticas incluem cirurgia, radiocirurgia estereotáxica ou vigilância clínico-imagiológica. Descrevemos o caso de um doente com um quadro agudo de paralisia facial periférica, otalgia e hipoacusia de condução esquerdas. O quadro clínico foi interpretado como uma otite média aguda complicada com paralisia facial com base na história, exame objetivo e achados imagiológicos de urgência. Por persistência das queixas, após uma semana, foi submetido a uma timpanomastoidectomia exploradora que confirmou o diagnóstico de schwannoma do nervo facial. Durante o procedimento foi efetuada uma ressecção subtotal da lesão, que se traduziu numa melhoria clínica e audiológica pós-operatória. Após resseção subtotal, optou-se por vigilância clínica e avaliação imagiológica regulares do resíduo tumoral.

Abstract Background: Since the beginning of the 21st century, fertility rates have decreased and life expectancy has increased, with more people with disabilities and dependent on others requiring more specialized nursing care. Objective: To describe the evolution of education/training in rehabilitation nursing. Methodology: Documental search conducted in the Portuguese official journal (Diário da República), with hermeneutic analysis and interpretation of the sources on the specialty of rehabilitation nursing since 2006. Results: Several curricula of postgraduate specialization and master’s degrees in rehabilitation nursing have been approved since 2006. Several course units were gradually integrated into the curricula, such as Statistical Epidemiology and Demography, Psychosocial Aspects of Disability, Health Care Policies and Models, and Internships in Rehabilitation Nursing Care for People with Cancer and at the End of Life. Conclusion: Education/training in rehabilitation nursing evolved under the influence of political and socio-demographic changes. With the technological and scientific advances and the evolution of health systems, rehabilitation nursing care has evolved in terms of innovation and education/training within a legal framework and based on specific competencies.

Resumen Marco contextual: Desde principios de siglo se ha producido un descenso de la natalidad y un mayor envejecimiento de la población, con más personas con discapacidad y dependencia, que requieren más cuidados especializados de enfermería. Objetivo: Describir la evolución en la formación de la especialidad en enfermería de rehabilitación. Metodología: Recopilación documental en el Diario de la República, con análisis e interpretación hermenéutica de las fuentes con referencia a la especialidad de enfermería de rehabilitación, publicadas desde 2006. Resultados: Se aprobaron varios planes de estudio de posgrado de especialización y máster en enfermería de rehabilitación. Progresivamente, se incluyeron unidades curriculares, como Epidemiología Estadística y Demografía, Aspectos Psicosociales de la Discapacidad, Políticas y Modelos de Atención Sanitaria y Prácticas de Atención de Enfermería de Rehabilitación a la Persona con Problemas Oncológicos y al Final de la Vida. Conclusión: La formación en enfermería de rehabilitación ha evolucionado con la influencia de los cambios políticos y sociodemográficos. Con los avances tecnológicos y científicos, así como con la evolución de los sistemas sanitarios, los cuidados de enfermería de rehabilitación han evolucionado en innovación y formación, con marcos legales y competencias específicas.

Resumo Enquadramento: Desde o início do século que se verifica uma diminuição da natalidade e maior envelhecimento populacional, existindo mais pessoas com incapacidade e dependência, exigindo cuidados de enfermagem mais especializados. Objetivo: Descrever a evolução na formação da especialidade em enfermagem de reabilitação. Metodologia: Recolha documental no Diário da República, com análise e interpretação hermenêutica das fontes com referência à especialidade de enfermagem de reabilitação, publicadas desde 2006. Resultados: Foram aprovados vários planos de estudo de pós-licenciatura de especialização e mestrado em enfermagem de reabilitação. Progressivamente, houve inclusão de unidades curriculares como Epidemiologia Estatística e Demografia, Aspetos Psicossociais da Incapacidade, Políticas e Modelos de Cuidados de Saúde e Estágios de Cuidados de Enfermagem de Reabilitação à Pessoa com Problemas Oncológicos e em Fim de Vida. Conclusão: A formação em enfermagem de reabilitação desenvolveu-se com influência das alterações políticas e sociodemográficas. Com os avanços tecnológicos, científicos e a evolução dos sistemas de saúde, os cuidados de enfermagem de reabilitação têm evoluído na inovação e formação, com enquadramento legal e nas competências específicas.

Resumo Introdução: Um teste rápido de diagnóstico de pneumonia tem o potencial de orientar decisões clínicas, como o início de antibioterapia, permitindo a redução do uso de antibióticos de amplo espectro. Contudo, a aceitação desses testes de diagnóstico está dependente da sua precisão. De forma a avaliar a assertividade diagnóstica e a precisão do painel de pneumonia BioFire® FilmArray® (BFFA) na identificação de microorganismos em secreções brônquicas, realizamos este estudo retrospetivo, que decorreu no Serviço de Medicina Intensiva (SMI) do CMHT. Métodos: Neste estudo foram incluídos todos os doentes (n = 104) internados no nosso SMI com pneumonia e que realizaram o teste BFFA, entre dezembro de 2019 e março de 2021. As amostras do trato respiratório inferior foram colhidas e analisadas simultaneamente pelo BFFA e pela cultura microbiológica. O painel BFFA incluiu 18 bac-térias e 8 vírus, que comumente causam pneumonia, bem como 7 genes de resistência a antibióticos, identificados a partir de amostras quer de aspirado traqueal, quer de lavado broncoalveolar (LBA). Resultados: Este estudo incluiu 104 pacientes, com idade média de 62 anos. O BFFA foi positivo em 111/125 (88%) das amostras colhidas. As bactérias mais comummente detetadas foram Staphylococcus aureus (19%), Klebsiella pneumonia (14%) e Haemophilus influenza (10%). Discussão: Foi possível inferir a forte concordância entre os resultados do BFFA e do exame cultural na deteção de bactérias. De facto, a maioria das bactérias (76/106 [72%]) detetadas pelo BFFA também foram identificadas na cultura. Por outro lado, é de realçar que de todos os BFFA negativos, apenas um teve isolamento de agente no exame cultural. Conclusão: A análise de amostras de secreções respiratórias em tempo real com o BFFA tem o potencial de identificar microorganismos, assim como marcadores de resistência, mais rapidamente do que os métodos tradicionais baseados no exame cultural. De facto, o BFFA é um método rápido e preciso para deteção de microorganismos causadores de infeções do trato respiratório inferior com proporção de concordância positiva de 72% e proporção de concordância negativa próxima de 100%, na população estudada.

Abstract Introduction: Rapid diagnostic testing for pneumonia has the presume potential to guide clinical decisions in reducing the use of broad-spectrum antibiotics. These benefits should be dependent upon the accuracy of these test. In order to evaluate the diagnostic yield and accuracy of the BioFire® FilmArray® pneumonia panel (BFFA) for pathogens identification in lower respiratory tract specimens, we conduct this retrospective study in a intensive care unit (ICU). Methods: In this study were included all patients (n = 104) admitted in our ICU with pneumonia who underwent BFFA test, between December 2019 and March 2021. Lower respiratory tract samples were collected and analysed simultaneously with BFPP and microbiological culture, as part of standard-of-care testing. The BFFA panel includes for 18 bacteria and 8 virus, that commonly cause pneumonia as well 7 antibiotic resistance genes, identified from tracheal aspirate or bronchial alveolar lavage (BAL) specimens. Results: This study included 104 patients, with an average age of 62 years. The BFFA was positive in 111/125 (88%) samples. The most common bacteria detected were Staphylococcus aureus (19%), Klebsiella pneumonia (14%) and Haemophilus influenza (10%). Discussion: There was strong concordance between BFFA and culture for detection of bacteria. In fact, most bacteria (76/106 [72%]) detected by BFFA were also identified in culture. In other hand, it is relevant that only one negative BFPP had an isolated agent in the cultural exam. Conclusion: Real-time specimen analysis with BFFA has the potential to identify bacterial and viral pathogens and theirs resistance markers, faster than traditional culture-based methods. In fact, the BFFA is a rapid and accurate method for detection of pathogens from lower respiratory tract infections with a 72% sensitivity and 100% specificity, in our studied population.

Abstract The intrauterine device is the most used long-acting reversible contraceptive method, presenting a low incidence of complications. The authors present a case of an intrauterine device migration, with an uterine perforation by its lower extremity.

Resumo O dispositivo intrauterino é o método contracetivo reversível de longa duração mais utilizado, apresentando uma baixa incidência de complicações. Os autores apresentam um caso de migração de um dispositivo intrauterino, em que se verificou perfuração uterina a partir da sua extremidade inferior.

ABSTRACT This study aims to analyse which are better step duration related to the maximum lactate steady-state test (MLSS) intensity and the intensity equivalent to the accumulation of 4mmol/L lactate (AnT4) determined through an incremental protocol using a rowing ergometer, using different steps durations (step3min, step5min, step7min). Ten elite Portuguese rowers (25.1± 4.82 years; 177.5± 5.50 cm; 69.8± 2.74 kg) performed rowing ergometer protocols to determine the maximum lactate steady state (MLSS). Subsequently, incremental tests were realised to determine AnT4, using different step durations (step3min, step5min, step7min). The results showed a strong correlation between MLSS and AnT4 (r> 0.90; p< 0.001) obtained AnT different steps (step3min, step5min, step7min). However, the determined intensity equivalent to 4 mmol/L obtained with different step durations that showed the highest correlation with MLSS (246.5± 35.20W) was verified in the protocol of 7minute steps (251.5± 35,72W). The present study indicates that the use of 7 minutes steps is the most appropriate for determining the AnT4 intensity related to the aerobic component of a high-performance rowing athlete.

Resumen Las plantas alimentícias no convencionales (PANC) son plantas espontáneas o cultivadas, capaces de ampliar las fuentes de nutrientes disponibles para la población y promover la soberania y seguridad alimentaria. A pesar del potencial que representan los PANC, la mayoría de las especies nativas de Brasil no forman parte del grupo de alimentos más consumidos en el país. El objetivo de este trabajo fue analizar el estado del arte de la investigación académica relacionada con PANC, utilizando un análisis bibliométrico de la investigación y producción científica mundial sobre el tema. Se identificaron un total de 2.056 artículos a partir de la investigación, con 50 términos de búsqueda, de los cuales 26 arrojaron resultados. Se observó un aumento de publicaciones sobre el tema, especialmente a partir de 1996. La fuente más relevante sobre el tema es el Journal of Ethnobiology and Ethnomedicine. Estados Unidos ocupan el primer lugar en cuanto al número de citas sobre el tema, y Brasil ocupa el puesto 28. Palabras como wild, edible, plant, flowers, food, traditional, indigenous e plants fueron las más citadas en los títulos de los artículos. A pesar del aumento de las investigaciones sobre el tema, el escenario aún es incipiente, considerando la gran cantidad de plantas entendidas como “no convencionales” existentes. PANC (PANC cultivadas alimentaria país 2056 2 056 2.05 5 búsqueda resultados 1996 Ethnomedicine 28 wild edible plant flowers food traditional incipiente existentes 205 05 2.0 199 20 0 2. 19 1

Abstract Unconventional food plants (PANC) are spontaneous or cultivated plants capable of expanding the sources of nutrients available to the population and promoting food sovereignty and security. Despite the potential that PANC represent, most native species in Brazil are not part of the most consumed food group in the country. The objective of this work was to analyze the state of the art of academic research related to PANC, using a bibliometric analysis of research and world scientific production on the subject. A total of 2.056 articles were identified from research with 50 search terms, of which 26 returned results. An increase in publications on the topic was observed, especially since 1996. The most relevant source on the topic is the Journal of Ethnobiology and Ethnomedicine. The United States ranks first in terms of the number of citations on the subject and Brazil ranks 28th. Words such as wild, edible, plant, flowers, food, traditional, indigenous, and plants were the most cited in article titles. Despite the increase in research on the subject, the scenario is still incipient considering the large number of plants understood as “unconventional” existing. (PANC security represent country 2056 2 056 2.05 5 results observed 1996 Ethnomedicine 28th th wild edible plant flowers traditional indigenous titles unconventional “unconventional existing 205 05 2.0 199 20 0 2. 19 1

Resumo As plantas alimentícias não convencionais (PANC) são plantas espontâneas ou cultivadas, capazes de ampliar as fontes de nutrientes disponíveis à população e promover a soberania e segurança alimentar. Apesar do potencial que as PANC representam, as espécies nativas do Brasil, em sua maioria, não fazem parte do grupo de alimentos mais consumidos no país. O objetivo do trabalho foi analisar o estado da arte das pesquisas acadêmicas relacionadas às PANC, utilizando uma análise bibliométrica de pesquisa e produção científica mundial a respeito do tema. Foram identificados 2.056 artigos provenientes de pesquisa, com 50 termos de busca, sendo que, desses, 26 retornaram resultados. Foi observado um aumento em publicações sobre o tema, em especial a partir de 1996. A fonte mais relevante sobre o tema é o Journal of Ethnobiology and Ethnomedicine. Os Estados Unidos ocupam o primeiro lugar em relação ao número de citações sobre a temática, e o Brasil ocupa a 28ª colocação. Palavras como wild, edible, plant, flowers, food, traditional, indigenous e plants foram as mais citadas em títulos dos artigos. Apesar do aumento das pesquisas acerca do tema, o cenário ainda é incipiente, considerando a grande quantidade de plantas compreendidas como “não convencionais” existentes. (PANC cultivadas alimentar representam maioria país 2056 2 056 2.05 5 busca desses resultados 1996 Ethnomedicine temática ª colocação wild edible plant flowers food traditional incipiente existentes 205 05 2.0 199 20 0 2. 19 1

ABSTRACT Introduction: Sleep disorders affect up to 70% of peritoneal dialysis (PD) patients and appear to have significant negative effects on their quality of life (QoL). We compared life and sleep quality between patients on automated PD (APD) and continuous ambulatory PD (CAPD). Material and Methods: Cross-sectional study in chronic PD patients followed in our Dialysis Unit in February 2022. We evaluated sleep quality with the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS) and QoL with EUROHIS-QOL-8. Results: Fifty-two patients, mostly men (65.4%, n=32), with a mean age of 52.7±14.2 years and PD vintage of 24.3±17.1 months. Our sample had similar distribution between APD and CAPD; we found no difference between groups regarding demographic data, PD-related quality parameters or prevalence of previous sleep disturbances. Mean QoL index was 69.9%±9.3% and similar between APD and CAPD patients; EUROHIS-QOL-8 negatively correlated with the scores on ESS (p=0.004) and PSQI (p=0.011). Regarding sleep quality, the mean ESS was 8.8±4.2 and PSQI was 7.6±3.6. APD patients had similar scores on ESS, but higher prevalence of severe daytime sleepiness (ESS≥18) (p=0.04) and higher scores on PSQI (p=0.002). Within the PSQI, sleep’ latency (p=0.003), duration (p=0.002) and efficiency (p=0.013) were the most affected parameters. Higher PSQI scores also correlated with worse blood pressure control; a cut-off value for PSQI of 6 was found to increase the risk of uncontrolled hypertension. Conclusion: In our series, APD patients had worse global sleep quality (PSQI) when compared to ACPD patients. This difference was mainly due to worse sleep latency, duration and efficiency. The assessment of the quality of life showed no difference between groups, however there was a clear link between quality of life and sleep quality.

ABSTRACT A 43-year-old male patient followed for 27 years in a Nephrology consultation with negative autoimmune diagnostic workup and a histologically proven membranous nephropathy (MN), interpreted as a primary MN. During the follow-up he had multiple relapses, requiring continuous immunosuppression. Eventually, end-stage renal disease developed and the patient started hemodialysis (HD) in January 2018. Soon after initiating HD, he was admitted to the ward due to persistent fever of unknown origin, refractory to antipyretic and antibiotic therapy, but responsive to prednisolone (40 mg/day). Again, the diagnostic workup was negative and the patient was discharged with a corticosteroid taper over 16 weeks. In a posterior admission, after prednisolone suspension, the patient presented to the emergency room with persistente fever, involuntary weight loss, pruriginous macular rash and inflammatory joint pain. As the anti-nuclear antibody and anti-dsDNA came up positive and there was complement consumption, a diagnosis of a systemic lupus flare was established. His stay was complicated by sudden respiratory distress associated with hemoptysis and hemoglobin drop, with a confirmed diffuse alveolar hemorrhage. Daily plasma Exchange and intensive immunosuppression was necessary and the patient evolved into complete clinical remission with partial serological response. Usually, patients with systemic lupus erythematosus (SLE) develop clinical and serological remission upon initiating HD, reducing the number of flares and need for medication. This case depicts a lupus flare after starting HD, on a previously serologically negative patient, complicated with a rare type of lung parenchyma involvement, which is associated with a high mortality and required intensive immunosuppression for disease control. One can speculate whether or not the initial glomerulopathy was the first manifestation of SLE, previously controlled due to the continuous use of immunosuppression.

ABSTRACT. To overcome the challenges encountered in banana cultivation, such as the high cost of production due to high water consumption by the banana plant, efficient management practices are being adopted. The use of agricultural forecasting techniques is an alternative that has been gaining attention in rural areas. One way to manage and improve agricultural productivity is the use of technologies that allow the monitoring of production. The implementation of computational tools as software to aid processes, such as irrigation management, is gradually taking up space in the agricultural sector. In this light, herein, the present study aimed to develop a model using STELLA 8.0 software to estimate the growth and productivity of irrigated banana (Musa sp.). For this, the physiological processes and water demand were calculated using reference evapotranspiration (ET0) and culture evapotranspiration (ETc) in the first banana cycle for the climatic conditions of the Jaíba Project (Jaíba, Minas Gerais State, Brazil). The data of the climatic conditions were obtained from the National Institute of Meteorology. It was verified that the average monthly ET0 was 5.78 mm day-1. In addition, the water requirement of the plant corresponded to a blade equivalent to 65% of ET0. The verified productivity was 8.93 t ha-1, which is considered adequate for the simulated conditions. The model responded efficiently to the proposed application and was characterized as a prognostic tool of reality through simplified representation. ABSTRACT cultivation adopted areas sector light herein 80 8 0 8. Musa sp.. sp sp. . sp.) ET (ET0 ETc (ETc Jaíba, (Jaíba State Brazil. Brazil Brazil) Meteorology 578 5 78 5.7 day1. day1 day 1. 1 day-1 addition 65 893 93 8.9 ha1, ha1 ha 1, ha-1 representation (ET 57 7 5. day- 6 89 9 ha-