Pesquisa | SciELO

Abstract Over the last three decades, stroke care has undergone significant transformations mainly driven by the introduction of reperfusion therapy and the organization of systems of care. Patients receiving treatment through a well-structured stroke service have a much higher chance of favorable outcomes, thereby decreasing both disability and mortality. In this article, we reviewed the scientific evidence for stroke reperfusion therapy, including thrombolysis and thrombectomy, and its implementation in the public health system in Brazil.

Resumo Nas últimas três décadas, o tratamento do AVC sofreu transformações significativas, impulsionadas principalmente pela introdução das terapias de reperfusão e pela organização dos serviços de AVC. Os pacientes que recebem tratamento em um serviço de AVC bem estruturado têm uma probabilidade muito maior de resultados favoráveis, diminuindo assim a incapacidade funcional e a mortalidade. Neste artigo, revisamos as evidências científicas para as terapias de reperfusão do AVC, incluindo trombólise e trombectomia e sua implementação no sistema público de saúde no Brasil.

https://doi.org/10.1055/s-0043-1777721

Capillary Electromigration Techniques Applied to Clinical Chemistry Investigations and Alternative Diagnostic Assays: Possibilities and Perspectives Assays
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Moreira, Olívia B. O.

; Berlande, Bruna M.

; Souza, Jéssica C. Q. de

; Candido, João Marcos B.

; Jaeger, Lauren H.

; Adriano, Luiz Henrique C.

; Brito, Marco Antônio D. A. e

; Nascimento, Maria Patrícia do

; Geraldo, Patrícia A.

; Chellini, Paula R.

; Oliveira, Marcone Augusto L. de

Journal of the Brazilian Chemical Society

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Nov 2023, Volume 34 Nº 11 Páginas 1542 - 1564

Resumo: En | Texto: En | PDF: En

Capillary electromigration techniques can be understood as the ones used to separate neutral compounds, solvated ions and ionized species, considering the differentiated migration among them when an electrical field is applied within a capillary column filled with a background electrolyte. Several existing capillary electrophoresis setups provide the possibility of developing reliable quantitative assays of inorganic ions, organic acids, fatty acids, amino acids, carbohydrates, nucleic acids, proteins, hormones, vitamins, macromolecules, and more. Therefore, given the chemical complexity of bodily fluid matrices, capillary electrophoresis (CE) and its variations present themselves as an advantageous strategy for enhancing traditional clinical diagnostic methods and for the development of new ones. The recent advances in the study of the human metabolome associated with technological improvements towards medical applications make CE a very useful and versatile technique for clinical laboratory assays. Within this context, this review has the purpose of presenting some traditional methods used for exams of blood, urine, saliva, feces, and sweat, and how CE can be implemented as a real alternative to enable faster, automated, and cost-effective analysis with a comprehensive perspective that shall result in better diagnostic possibilities for patients, being a powerful tool for helping physicians on the precision medicine achievements. compounds species electrolyte acids carbohydrates proteins hormones vitamins macromolecules more Therefore matrices (CE context blood urine saliva feces sweat faster automated costeffective cost effective patients achievements

https://doi.org/10.21577/0103-5053.20230096

Seasonal and Circadian Evaluation of the Pectis brevipedunculata Essential Oil and Its Acaricidal Activity against Rhipicephalus microplus (Acari: Ixodidae)
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Camara, Marcos B. P.

; Lima, Aldilene S.

; Jumbo, Luis Oswaldo V.

; Tavares, Caio P.

; Mendonça, Cáritas de Jesus S.

; Monteiro, Odair S.

; Araújo, Sabrina Helena C.

; Oliveira, Eugênio Eduardo de

; Lima Neto, José S.

; Maia, José Guilherme S.

; Costa Junior, Livio M.

; Rocha, Cláudia Q. da

Journal of the Brazilian Chemical Society

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Jul 2023, Volume 34 Nº 7 Páginas 1020 - 1029

Resumo: En | Texto: En | PDF: En

Pectis brevipedunculata is native species and widely available in dry and semi-arid ecosystems showing high biotechnological potential. The objective of this study was to evaluate the circadian and seasonal chemical variation of the essential oil (EO) of P. brevipedunculata, as well as its acaricide effect on Rhipicephalus microplus larvae. Aerial parts were collected and submitted to the hydrodistillation process, and the chemical composition was determined by gas chromatography mass spectrometry (GC-MS). For the assays with R. microplus, the larval immersion test was performed. The main constituents were citral (75% of the EO), followed by α-pinene and limonene. In the seasonality analysis, the highest yields were in the months of April (2.08%) and August (2.05%), while in the study of circadian rhythm, the percentage was 2.0% at 6 p.m. in the rainy season, and 1.2%, dry season at 6 p.m. Concerning acaricidal activity (50% lethal concentration (LC50)), the April (1.17 mg mL-1), March (1.28 mg mL-1), June (1.37 mg mL-1), and October (1.27 mg mL-1) oils obtained were the most active and assays performed with circadian rhythm revealed in the rain season (April) at 6 p.m. and dry season (September) at 12 a.m. LC50 values of 1.75 and 1.75 mg mL-1, respectively. Additionally, this EO is selective to non-target organisms, i.e., ladybeetles and lacewing.

https://doi.org/10.21577/0103-5053.20230017

Fitting Structure-Data Files (.SDF) Libraries to Progenesis QI Identification Searches
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Sanches, Pedro H. G.

; Oliveira, Danilo C. de

; Reis, Ivan G. M. dos

; Fernandes, Anna M. A. P.

; Silva, Alex A. R.

; Eberlin, Marcos N.

; Carvalho, Patrícia O.

; Duarte, Gustavo H. B.

; Porcari, Andreia M.

Journal of the Brazilian Chemical Society

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Jul 2023, Volume 34 Nº 7 Páginas 1013 - 1019

Resumo: En | Texto: En | PDF: En

Progenesis QI (PQI) is a multiplatform bioinformatics tool that facilitates the identification workflow for metabolomics experiments. PQI uses fragmentation data provided by MassBank of North America (MoNA) libraries, among others, for metabolite annotation. However, PQI does not officially support MoNA libraries and other libraries based on structure-data files (.sdf). This paper describes the development and application of a software named MoNA to Progenesis QI Library Converter, allowing PQI and MoNA by correcting the fragmentation data of the library for Progenesis readability. We evaluated several public experimental datasets, including human plasma, plant extracts, cultured cells, bacteria, rat serum, and rat hippocampus. The results showed that it is mandatory to proceed with file conversion of each library to allow PQI to access fragmentation information from .msp (main spectra profile) files. This step is highly recommended to improve the identification level of the metabolites.

https://doi.org/10.21577/0103-5053.20230016

ESTUDO DE GASOLINAS PREMIUM E COMUM COMERCIALIZADAS NO BRASIL ATRAVÉS DO MÉTODO ERETIC-RMN E QUIMIOMETRIA ERETICRMN ERETIC RMN
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Pinto, Vinícius S.

; Oliveira, Gerlon de A. R.

; Gomides, Christian D.

; Monteiro, Marcos R.

; Lião, Luciano M.

Química Nova

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Fev 2023, Volume 46 Nº 2 Páginas 171 - 178

Resumo: Pt | Texto: Pt | PDF: Pt

Gasoline is a complex mixture of hydrocarbons whose detailed study of its chemical profiles is a challenging task. This type of product of great commercial importance has its quality measured in Brazil from classical physical-chemical tests. Although robust, physical-chemical analyses generally require large amounts of assays, solvents, and samples, in addition to not being indicated for the detection of small compositional changes. In this work, NMR and chemometrics were used in the quantitative study of different samples of gasoline with varying ratings of octane and ethanol contents. The results demonstrated the usefulness of NMR spectroscopy both to characterize as well as to distinguish the chemical profiles of regular and premium gasoline. With the application of the ERETIC, the chemical profiles mentioned were quantitatively differentiated and the proportions between hydrocarbons were determined for both types of gasoline. The application of the ERETIC was also successful in the quantitative determination of ethanol contents in regular and premium gasoline. The aforementioned method, which dispenses with the use of quantification standards inserted directly into the sample of interest, was unequivocal in accounting for the volume of ethanol, in addition to showing excellent agreement with the method currently adopted by the Brazilian government. task physicalchemical physical tests robust assays solvents changes work interest government

https://doi.org/10.21577/0100-4042.20230004

Perfil epidemiológico e distribuição espacial dos casos de hanseníase na Paraíba
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Véras, Gerlane Cristinne Bertino

; Soares, Maria Júlia Guimarães Oliveira

; Silva, Luiz Henrique da

; Moraes, Ronei Marcos de

Cadernos Saúde Coletiva

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2023, Volume 31 Nº 2 elocation e31020488

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background Leprosy presents itself heterogeneously, which requires the recognition of profile and spatial distribution for the effectuation of control actions. Objective To describe the epidemiological profile and the spatial distribution of leprosy cases in the Paraíba, Brazil. Method Ecological study on a secondary basis with a quantitative approach. The study site was the 223 municipalities in the state of Paraíba. The data were collected in the Notifiable Diseases Information System/Leprosy for the period from 2015 to 2019. Descriptive statistics and spatial analysis were used with the aid of the R software. Results 3,218 cases were analyzed for the epidemiological profile and 3,212 for the spatial analysis. There was a greater record in the year of 2019 (n = 778;24.2%); in males (n = 1,783; 55.5%); age group 40 to 59 years (n = 1,236; 38.4%); multibacillary classification (n = 2,095; 65.2%); dysmorphic form (n = 970; 30.2%); and degree of physical disability 0 (n = 1,611; 50.2%). 171 (76.7%) municipalities that reported cases were identified, and simple and compound conglomerates were detected involving 31 municipalities located further east and west of the state. Conclusion It should be noted that leprosy remains an active transmission chain in Paraíba and has a heterogeneous geographic distribution, reaffirming the importance of planning and executing more resolute control actions.

Resumo Introdução A hanseníase se apresenta de forma heterogênea, o que requer o reconhecimento do perfil e distribuição espacial para a efetivação de ações de controle. Objetivo Descrever o perfil epidemiológico e a distribuição espacial dos casos de hanseníase na Paraíba. Método Estudo ecológico, de base secundária e abordagem quantitativa. Os loci do estudo foram os 223 municípios do estado. Os dados foram coletados no Sistema de Informação de Agravos de Notificação/Hanseníase correspondentes ao período de 2015 a 2019. Utilizou-se de estatística descritiva e análise espacial com auxílio do software R. Resultados Foram analisados 3.218 casos para o perfil epidemiológico e 3.212 para a análise espacial. Verificou-se maior registro no ano de 2019 (n=778;24,2%); no sexo masculino (n=1.783; 55,5%); faixa etária 40 a 59 anos (n=1.236; 38,4%); classificação multibacilar (n=2.095; 65,2%); forma dimorfa (n= 970; 30,2%), e grau de incapacidade física 0 (n=1.611; 50,2%). Identificaram-se 171 (76,7%) municípios que notificaram casos, e houve detecção de conglomerados simples e compostos envolvendo 31 municípios, situados mais ao Leste e Oeste do estado. Conclusão Ressalta-se que a hanseníase permanece com cadeia de transmissão ativa na Paraíba e com distribuição geográfica heterogênea, reafirmando a importância de planejar e executar ações de controle mais resolutivas.

https://doi.org/10.1590/1414-462x202331020488

Long-term Ecological Research: Chasing fashions or being prepared for fashion changes?
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BERGALLO, HELENA G.

; ROSA, CLARISSA

; OCHOA, ANA C.

; MANZATTO, ANGELO GILBERTO

; GUIMARAES, ARETHA F.

; BANHOS, AUREO

; CASTILHO, CAROLINA V.

; BARROS, CLAUDIA F.

; NORRIS, DARREN

; DRUCKER, DEBORA P.

; RODRIGUES, DOMINGOS J.

; BACCARO, FABRICIO B.

; LOURENÇO, IGOR H.

; ZUANON, JANSEN

; STEGMANN, LIS F.

; ANJOS, MARCELO R.

; SILVEIRA, MARCOS

; ARAÚJO, PATRICIA S.G.

; BOBROWIEC, PAULO E.D.

; FADINI, RODRIGO

; NECKEL-OLIVEIRA, SELVINO

; EMILIO, THAISE

; SANTORELLI JUNIOR, SERGIO

; MAGNUSSON, WILLIAM E.

Anais da Academia Brasileira de Ciências

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2023, Volume 95 Nº 3 elocation e20230051

Resumo: En | Texto: En | PDF: En

Abstract Long-term-ecological-research (LTER) faces many challenges, including the difficulty of obtaining long-term funding, changes in research questions and sampling designs, keeping researchers collecting standardized data for many years, impediments to interactions with local people, and the difficulty of integrating the needs of local decision makers with “big science”. These issues result in a lack of universally accepted guidelines as to how research should be done and integrated among LTER sites. Here we discuss how the RAPELD (standardized field infrastructure system), can help deal with these issues as a complementary technique in LTER studies, allowing comparisons across landscapes and ecosystems and reducing sampling costs. RAPELD uses local surveys to understand broad spatial and temporal patterns while enhancing decision-making and training of researchers, local indigenous groups and traditional communities. Sampling of ecological data can be carried out by different researchers through standardized protocols, resulting in spatial data that can be used to answer temporal questions, and allow new questions to be investigated. Results can also be integrated into existing biodiversity networks. Integrated systems are the most efficient way to save resources, maximize results, and accumulate information that can be used in the face of the unknown unknowns upon which our future depends.

https://doi.org/10.1590/0001-3765202320230051

Diretriz da Sociedade Brasileira de Cardiologia sobre a Análise e Emissão de Laudos Eletrocardiográficos – 2022
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Samesima, Nelson

; God, Epotamenides Good

; Kruse, Jose Claudio Lupi

; Leal, Marcelo Garcia

; Pinho, Claudio

; França, Francisco Faustino de A. C.

; Pimenta, João

; Cardoso, Acácio Fernandes

; Paixão, Adail

; Fonseca, Alfredo

; Pérez-Riera, Andrés R.

; Ribeiro, Antonio Luiz Pinho

; Madaloso, Bruna Affonso

; Luna Filho, Bráulio

; Oliveira, Carlos Alberto Rodrigues de

; Grupi, César José

; Moreira, Dalmo Antonio Ribeiro

; Kaiser, Elisabeth

; Paixão, Gabriela Miana de Mattos

; Feitosa Filho, Gilson

; Pereira Filho, Horacio Gomes

; Grindler, José

; Aziz, José Luiz

; Molina, Marcos Sleiman

; Facin, Mirella

; Tobias, Nancy M. M. de Oliveira

; Oliveira, Patricia Alves de

; Sanches, Paulo César R.

; Teixeira, Ricardo Alkmin

; Atanes, Severiano Melo

; Pastore, Carlos Alberto

Arquivos Brasileiros de Cardiologia

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Out 2022, Volume 119 Nº 4 Páginas 638 - 680

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20220623

Biologically Active Volatile Organic Compounds (VOCs) Produced by Rhizospheric Actinobacteria Strains Inhibit the Growth of the Phytopathogen Colletotrichum musae
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Brito, Maria V. de

; Fonseca, Wéverson L.

; Mafezoli, Jair

; Barbosa, Francisco G.

; Nunes, Fátima M.

; Mattos, Marcos C. de

; Santos, João E. A. dos

; Araujo, Francisca S. A.

; Vieira, Regimara F. B. S.

; Magalhães, Hilton C. R.

; Muniz, Celli R.

; Garruti, Deborah S.

; Ootani, Marcio A.

; Souza Netto, José M.

; Pinto, Licarion

; Viana, Francisco M. P.

; Oliveira, Maria C. F.

Journal of the Brazilian Chemical Society

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Out 2022, Volume 33 Nº 10 Páginas 1172 - 1189

Resumo: En | Texto: En | PDF: En

The antifungal potential of volatile organic compounds (VOCs) produced by actinobacterial strains Streptomyces sp. (ACTB-77) and Amycolatopsis sp. (ACTB-290) from the rhizosphere of Caatinga plants against Colletotrichum musae was investigated. VOCs produced by these microorganisms (axenic and co-culture) were investigated using headspace-solid phase micro-extraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS). Although no exclusive VOC peaks were observed in the co-culture with ACTB-77, the same experiment involving ACTB-290 yielded five new peaks, including two identified alcohols, suggested as bioreductive products of the corresponding ketones by the fungus. Statistical analysis revealed that co-culture ACTB-77/C. musae has a closer similarity to the fungus than to the actinobacteria, while the co culture ACTB-290/C. musae showed closer similarity to the actinobacteria. These confirmed the more pronounced antifungal activity of the ACTB-290 strain, as observed in the fungus growth inhibition experiments. The antifungal activity of ACTB-290 was associated to its sulfur-containing metabolites, while linalool was suggested as responsible for the ACTB-77 activity.

https://doi.org/10.21577/0103-5053.20220037

10.

TESTES DIAGNÓSTICOS PARA O SARS-COV-2: UMA REFLEXÃO CRÍTICA
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Oliveira, Marcone A. L. de

; Watanabe, Aripuanã S. A.

; Cesar, Dionéia E.

; Candido, João Marcos B.

; Lima, Nerilson M.

; Moreira, Olívia B. O.

; Chellini, Paula R.

Química Nova

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Jun 2022, Volume 45 Nº 6 Páginas 760 - 766

Resumo: Pt | Texto: Pt | PDF: Pt

The new coronavirus, called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), was discovered in late December 2019 after cases were reported in the city of Wuhan, China. In January 2020, the World Health Organization (WHO) officially declared the Coronavirus Disease 2019 (COVID-19) as a pandemic, which has an official record of around 500 million cases and more than 6.0 million deaths in worldwide. An important factor in controlling the pandemic is the development of more effective and efficient diagnostic tests. In this context, this review has as its main proposal to discuss the effective differences between the possible diagnostic tests, the implications of molecular and serological methods available on the market and the analytical and clinical parameters involved in the development and application of these methods.

https://doi.org/10.21577/0100-4042.20170895

11.

Nutrients in ‘Gigante’ forage cactus pear under different saline water irrigation depths and planting densities
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Fonseca, Varley A.

; Donato, Sérgio L. R.

; Santos, Marcelo R. dos

; Oliveira, Carlos M.

; Kondo, Marcos K.

; Cotrim, Carlos E.

Revista Brasileira de Engenharia Agrícola e Ambiental

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Mai 2022, Volume 26 Nº 5 Páginas 381 - 389

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Variações climáticas tendem a aumentar a ocorrência de condições extremas de seca em ambientes semiáridos e isso pode comprometer o rendimento mesmo de culturas tolerantes como palma forrageira. A irrigação da palma com água salina têm possibilitado bons resultados, e sua combinação com modificações nas densidades de plantio pode refletir em mudanças na resposta produtiva da cultura. Um experimento de campo em dois ciclos de cultivo foi realizado para avaliar as concentrações de nutrientes em palma forrageira ‘Gigante’ (Opuntia ficus-indica Mill) irrigada sob diferentes laminas de água salina e densidades de plantio. O delineamento experimental foi em blocos casualizados em esquema de parcelas subsubdivididas, sendo alocados nas parcelas dois turnos de rega (7 e 14 dias), nas subparcelas quatro densidades de plantio (20.000; 40.000; 60.000 e 80.000 plantas ha-1) e nas subsubparcelas quatro lâminas de irrigação com água salina de condutividade elétrica de 2,91 dS m-1 (0, 11, 22 e 33% da evapotranspiração de referência - ETo). As lâminas de irrigação foram aplicadas somente no período do ano sem chuva. Densidades de plantio intermediárias (43.002 e 54.687 plantas ha-1) promovem menores concentrações de P, Ca e Fe nos tecidos dos cladódios de palma forrageira ‘Gigante’. Irrigação de palma forrageira ‘Gigante’ com água salina até a lâmina 33% da ETo, possibilita aumento das concentrações de N, P, Ca, Mg, B, Cu, Mn e Zn nos tecidos dos cladódios. Lâminas de irrigação entre 16 e 25% da ETo com água salina, promove máximas concentrações de K, S e Na.

ABSTRACT Climate variability tends to increase the occurrence of extreme drought conditions in semi-arid regions, thereby compromising crop yield, including that of drought-tolerant plants such as forage cactus pear. Irrigation of cactus with saline water has enabled good results, and its combination with changes in planting densities may promote changes in the production response of this crop. A field experiment spanning two crop cycles was carried out to evaluate nutrient concentrations in ‘Gigante’ forage cactus pear (Opuntia ficus-indica Mill) under different saline water irrigation depths and planting densities. A randomized block design was used with treatments arranged in split-split plots. Two irrigation intervals (7 and 14 days) were assigned to plots, four planting densities (20,000; 40,000; 60,000 and 80,000 plants ha-1) to subplots, and four irrigation depths of saline water of electrical conductivity 2.91 dS m-1 (0, 11, 22 and 33% of reference evapotranspiration) to sub-subplots. The irrigation depths were applied only in the period of the year without rain. Intermediate planting densities (43,002 and 54,687 plants ha-1) promote lower P, Ca and Fe concentrations in cladode tissues of forage cactus pear. Irrigating ‘Gigante’ cactus forage with saline water up to 33% ETo increases the concentrations of N, P, Ca, Mg, B, Cu, Mn and Zn in cladode tissues. Irrigation levels between 16 and 25% of ETo with saline water resulted in the highest concentrations of K, S and Na.

https://doi.org/10.1590/1807-1929/agriambi.v26n5p381-389

12.

Art and science: impact of semioccluded vocal tract exercises and choral singing on quality of life in subjects with congenital GH deficiency
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Andrade, Bruna M. R. de

; Valença, Eugenia H. O.

; Salvatori, Roberto

; Oliveira Neto, Luiz A.

; Souza, Anita H. O.

; Oliveira, Alaíde H. A.

; Oliveira, Mario C.P.

; Melo, Enaldo V.

; Carvalho, Susana de

; Sales, Neuza J

; Monteiro, Gisane C.

; Lima, José Marcel de

; Annunziato, Marcos Felipe Harder

; Mannis, Guilherme Daniel Breternitz

; Souza, Lucas E. de A.

; Goes, Yasmin D.

; Carvalho, Thayza S.

; Farias, Celiane de

; Santos, Michela P. dos

; Cardoso, Gabriela P. F.

; Sousa, Carla S. Pereira

; Santana, Julia Rodrigues

; Sales, Ester Almeida

; d’Avila, Jeferson Sampaio

; Aguiar-Oliveira, Manuel H.

Archives of Endocrinology and Metabolism

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Abr 2022, Volume 66 Nº 2 Páginas 198 - 205

Resumo: En | Texto: En | PDF: En

ABSTRACT Objectives: Currently, not much is known about the interactions between voice and growth hormone (GH). We have described large kindred with isolated GH deficiency (IGHD) due to a GHRH receptor mutation, resulting in severe short stature and high-pitched voice. These IGHD individuals have little interest in GH treatment, as they consider themselves “short long-lived people”, rather than patients. Interestingly, they report normal general quality of life, but they rate their Voice-Related Quality of Life (V-RQOL) as low. Here, we assessed the social and auditory-perceptual impacts of artistic-intervention voice therapy with semioccluded vocal tract exercises (SOVTE) and choral singing, on their voices. Material and methods: Seventeen GH-naïve adult IGHD individuals were enrolled in a single-arm interventional pre-post study with 13 weekly sessions of choir singing over 90 days. Outcome measures were V-RQOL scores, self-assessment of voice, and auditory-perceptual analysis (GRBAS scale, G: grade of the severity of dysphonia; R: roughness; B: breathiness; A: asthenia; and S: strain). Results: Marked improvements in total (p = 0.0001), physical (p = 0.0002), and socioemotional (p = 0.0001) V-RQOL scores and in self-assessment of voice (p = 0.004) were found. The general grades of vocal deviation (p = 0.0001), roughness (p = 0.0001), breathiness (p = 0.0001) and strain (p = 0.0001) exhibited accentuated reductions. Conclusions: Voice therapy with semioccluded vocal tract exercises and choral training improved social impact and perceptual voice assessments in IGHD subjects and markedly improved their voice-related quality of life. This is particularly important in a setting where GH replacement therapy is not widely accepted.

https://doi.org/10.20945/2359-3997000000449

13.

Semi-analytical Equations for Designing Terahertz Graphene Dipole Antennas on Glass Substrate
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Garcia, Marcos E. C.

; Oliveira, Rodrigo M. S. de

; Rodrigues, Nilton R. N. M.

Journal of Microwaves, Optoelectronics and Electromagnetic Applications

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Mar 2022, Volume 21 Nº 1 Páginas 11 - 34

Resumo: En | Texto: En | PDF: En

Abstract Semi-analytical equations are developed for aiding the process of designing terahertz graphene-based rectangular dipole antennas lying on glass substrates. It directly provides the dipole length required for obtaining resonance at a desired frequency since antenna width and graphene chemical potential are known. By using the finite-difference time-domain (FDTD) method, a large number of computational simulations were performed considering several combinations of antenna dimensions and chemical potential values. The simulation results were used along with graphene electrostatic scaling law combined with the least squares method to optimize the formulation coefficients. With the optimized coefficients, we obtain very satisfying accuracy levels. In the frequency range from 0.5 THz to 3.0 THz, the average relative absolute error is 1.50%, with maximum relative absolute error of 6.77%.

https://doi.org/10.1590/2179-10742022v21i11335

14.

Selection of F2RC1 saladette-type dwarf tomato plant populations for fruit quality and whitefly resistance
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Oliveira, Camila S. de

; Maciel, Gabriel M.

; Siquieroli, Ana C. S.

; Gomes, Danilo A.

; Martins, Marcos P. do C.

; Finzi, Rafael R.

Revista Brasileira de Engenharia Agrícola e Ambiental

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Jan 2022, Volume 26 Nº 1 Páginas 28 - 35

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo do estudo foi selecionar populações F2RC1 de tomateiro anão do tipo saladete promissoras para o desenvolvimento de linhagens baseado em características agronômicas, qualidade de fruto e resistência a mosca branca. O delineamento experimental foi em blocos casualizados contendo 13 tratamentos (10 populações F2RC1 de tomateiro anão, genitores e híbrido comercial) com quatro repetições. Foram avaliados: peso, comprimento, diâmetro, formato, espessura da polpa, número de lóculos, teores de sólidos solúveis, β-caroteno e licopeno do fruto; comprimento do entrenó da planta; teores de acilaçúcares, número de ovos, ninfas e adultos de mosca branca nos folíolos. Os dados foram analisados por ANOVA, índices de seleção e análise multivariada. O primeiro retrocruzamento aumentou as características agronômicas das populações em relação ao genitor doador, principalmente para peso de fruto (169.1%), comprimento do fruto (26.1%) e diâmetro do fruto (16.6%). As populações UFU SDi 7, UFU SDi 9 e UFU-SDi 17 foram selecionadas por dois índices de seleção e são consideradas promissoras.

ABSTRACT This study aimed to select promising F2RC1 populations of saladette-type dwarf tomato plants for the development of breeding lines based on agronomic characteristics, fruit quality, and whitefly resistance. The experimental design was randomized blocks containing 13 treatments (10 F2RC1 populations of dwarf tomato plants, both parents, and a commercial hybrid) with four replicates. The evaluations were performed included weight, length, diameter, shape, pulp thickness, number of locules, soluble solids, β-carotene, and lycopene concentration of the fruit; plant internode length; acylsugars concentration; and number of whitefly eggs, nymphs, and adults on the leaflets. The data were analyzed using ANOVA, selection indices, and multivariate analysis. The first backcross increased the agronomic characteristics of the populations in relation to the donor parent, especially for fruit weight (169.1%), fruit length (26.1%), and fruit diameter (16.6%). The UFU SDi 7, UFU SDi 9, and UFU-SDi 17 populations were selected using two selection indices and were therefore considered promising.

https://doi.org/10.1590/1807-1929/agriambi.v26n1p28-35 42 downloads

15.

Thyroid collision tumor containing oncocytic carcinoma, classical and hobnail variants of papillary carcinoma and areas of poorly differentiated carcinoma
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Toyoshima, Marcos Tadashi Kakitani

; Domingues, Regina Barros

; Soares, Ibere Cauduro

; Danilovic, Debora Lucia Seguro

; Amorim, Larissa Costa

; Cavalcante, Edla R. C.

; Antonacio, Fernanda F.

; Roitberg, Felipe Santa Rosa

; Hoff, Ana Oliveira

Archives of Endocrinology and Metabolism

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Ago 2021, Volume 65 Nº 4 Páginas 495 - 499

Resumo: En | Texto: En | PDF: En

SUMMARY Collision tumors are rare and may comprise components with different behavior, treatments, and prognosis. We report an unprecedented case of aggressive thyroid collision tumor containing widely invasive oncocytic carcinoma (OC), classical and hobnail (HPTC) variants of papillary carcinoma, and poorly differentiated carcinoma (PDTC). The patient underwent total thyroidectomy, radioactive iodine therapy, and within months progressed with local recurrence, and pulmonary metastases requiring neck dissection, external radiotherapy and systemic treatment with sorafenib. The rapid progression, dedifferentiated metastatic lesions, and failure to treatments resulted in the patient´s death. The great variety of histological types and the evolution of this case were a challenge for the management of metastatic disease. Widely invasive OC, HPTC and PDTC are considered to have a worse prognosis. HPTC has never been reported as a component of a collision tumor. HPTC and PDTC should call attention to a possible higher-grade transformation.

https://doi.org/10.20945/2359-3997000000389 234 downloads

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