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[SciELO Preprints] - Guidelines on the Diagnosis and Treatment of Hypertrophic Cardiomyopathy – 2024
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Fernandes, Fabio Simões, Marcus V. Correia, Edileide de Barros Marcondes-Braga, Fabiana G. Coelho-Filho, Otavio Rizzi Mesquita, Cláudio Tinoco Mathias-Junior, Wilson Rochitte, Carlos Eduardo Ramires, Felix José Alvarez Alves, Silvia Marinho Martins Montera, Marcelo Westerlund Lopes, Renato Delascio Oliveira-Junior, Mucio Tavares Scolari, Fernando L. Avila, Walkiria Samuel Canesin, Manoel Fernandes Bacal, Fernando Bocchi, Edimar Alcides Moura, Lídia Ana Zytynski Saad, Eduardo Benchimol Scanavacca, Mauricio I. Valdigem, Bruno Pereira Cano , Manuel Nicolas Abizaid , Alexandre Ribeiro, Henrique Barbosa Lemos-Neto, Pedro Alves Ribeiro, Gustavo Calado de Aguiar Jatene, Fabio Biscegli Dias, Ricardo Ribeiro Beck-da-Silva, Luis Rohde, Luis Eduardo P. Bittencourt, Marcelo Imbroinise Pereira, Alexandre Krieger, José Eduardo Villacorta, Humberto Martins, Wolney de Andrade Figueiredo-Neto, José Albuquerque de Cardoso , Juliano Novaes Pastore, Carlos Alberto Jatene, Ieda Biscegli Tanaka, Ana Cristina Sayuri Hotta, Viviane Tiemi Romano, Minna Moreira Dias Albuquerque, Denilson Campos de Mourilhe-Rocha, Ricardo Hajjar, Ludhmila Abrahão Brito, Fabio Sandoli de Caramelli , Bruno Calderaro, Daniela Farsky, Pedro Silvio Colafranceschi , Alexandre Siciliano Pinto, Ibraim Masciarelli Vieira , Marcelo Luiz Campos Danzmann, Luiz Claudio Barberato , Silvio Henrique Mady, Charles Martinelli-Filho, Martino Torbey , Ana Flavia Malheiros Schwartzmann, Pedro Vellosa Macedo, Ariane Vieira Scarlatelli Ferreira , Silvia Moreira Ayub Schmidt, Andre Melo , Marcelo Dantas Tavares de Lima-Filho, Moysés Oliveira Sposito, Andrei C. Brito, Flavio de Souza Biolo, Andreia Madrini-Junior, Vagner Rizk, Stéphanie Itala Mesquita, Evandro Tinoco

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Data de publicação: 2024-04-08

Resumo: Pt Es En

A cardiomiopatia hipertrófica (CMH) é uma forma de doença do músculo cardíaco de causa genética, caracterizada pela hipertrofia das paredes ventriculares. O diagnóstico requer detecção por métodos de imagem (Ecocardiograma ou Ressonância Magnética Cardíaca) de qualquer segmento da parede do ventrículo esquerdo com espessura > 15 mm, sem outra causa provável. A análise genética permite identificar mutações de genes codificantes de diferentes estruturas do sarcômero responsáveis pelo desenvolvimento da CMH em cerca de 60% dos casos, permitindo o rastreio de familiares e aconselhamento genético, como parte importante do manejo dos pacientes e familiares. Vários conceitos sobre a CMH foram recentemente revistos, incluindo sua prevalência de 1 em 250 indivíduos, não sendo, portanto, uma doença rara, mas subdiagnosticada. A vasta maioria dos pacientes é assintomática. Naqueles sintomáticos, a obstrução do trato de saída do ventrículo esquerdo (OTSVE) é o principal distúrbio responsável pelos sintomas, devendo-se investigar a sua presença em todos os casos. Naqueles em que o ecocardiograma em repouso ou com Manobra de Valsalva não detecta gradiente intraventricular significativo (> 30 mmHg), devem ser submetidos à ecocardiografia com esforço físico para detecção da OTSVE.   Pacientes com sintomas limitantes e grave OTSVE, refratários ao uso de betabloqueadores e verapamil, devem receber terapias de redução septal ou uso de novas drogas inibidoras da miosina cardíaca. Por fim, os pacientes adequadamente identificados com risco aumentado de morta súbita podem receber medida profilática com implante de cardiodesfibrilador implantável (CDI).

La miocardiopatía hipertrófica (MCH) es una forma de enfermedad cardíaca de origen genético, caracterizada por el engrosamiento de las paredes ventriculares. El diagnóstico requiere la detección mediante métodos de imagen (Ecocardiograma o Resonancia Magnética Cardíaca) que muestren algún segmento de la pared ventricular izquierda con un grosor > 15 mm, sin otra causa probable. El análisis genético permite identificar mutaciones en genes que codifican diferentes estructuras del sarcómero responsables del desarrollo de la MCH en aproximadamente el 60% de los casos, lo que permite el tamizaje de familiares y el asesoramiento genético, como parte importante del manejo de pacientes y familiares. Varios conceptos sobre la MCH han sido revisados recientemente, incluida su prevalencia de 1 entre 250 individuos, por lo tanto, no es una enfermedad rara, sino subdiagnosticada. La gran mayoría de los pacientes son asintomáticos. En los casos sintomáticos, la obstrucción del tracto de salida ventricular izquierdo (TSVI) es el trastorno principal responsable de los síntomas, y su presencia debe investigarse en todos los casos. En aquellos en los que el ecocardiograma en reposo o la maniobra de Valsalva no detecta un gradiente intraventricular significativo (> 30 mmHg), deben someterse a ecocardiografía de esfuerzo para detectar la obstrucción del TSVI. Los pacientes con síntomas limitantes y obstrucción grave del TSVI, refractarios al uso de betabloqueantes y verapamilo, deben recibir terapias de reducción septal o usar nuevos medicamentos inhibidores de la miosina cardíaca. Finalmente, los pacientes adecuadamente identificados con un riesgo aumentado de muerte súbita pueden recibir medidas profilácticas con el implante de un cardioversor-desfibrilador implantable (CDI).

Hypertrophic cardiomyopathy (HCM) is a form of genetically caused heart muscle disease, characterized by the thickening of the ventricular walls. Diagnosis requires detection through imaging methods (Echocardiogram or Cardiac Magnetic Resonance) showing any segment of the left ventricular wall with a thickness > 15 mm, without any other probable cause. Genetic analysis allows the identification of mutations in genes encoding different structures of the sarcomere responsible for the development of HCM in about 60% of cases, enabling screening of family members and genetic counseling, as an important part of patient and family management. Several concepts about HCM have recently been reviewed, including its prevalence of 1 in 250 individuals, hence not a rare but rather underdiagnosed disease. The vast majority of patients are asymptomatic. In symptomatic cases, obstruction of the left ventricular outflow tract (LVOT) is the primary disorder responsible for symptoms, and its presence should be investigated in all cases. In those where resting echocardiogram or Valsalva maneuver does not detect significant intraventricular gradient (> 30 mmHg), they should undergo stress echocardiography to detect LVOT obstruction. Patients with limiting symptoms and severe LVOT obstruction, refractory to beta-blockers and verapamil, should receive septal reduction therapies or use new drugs inhibiting cardiac myosin. Finally, appropriately identified patients at increased risk of sudden death may receive prophylactic measure with implantable cardioverter-defibrillator (ICD) implantation.

https://doi.org/10.1590/SciELOPreprints.8394

Therapeutic Adherence According to the Morisky Scale in Patients with Hypertension
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Lanza, Vinícius Encenha

; Silva, Gabriel Oliveira

; Quiroga, Celi Cristina Calamita

; Cavalcante, Margaret Assad

; Barroso, Weimar Kunz Sebba

; Brandão, Andréa Araujo

; Barbosa, Eduardo Costa Duarte

; Malachias, Marcus Vinicius Bolivar

; Gomes, Marco Mota

; Amodeo, Celso

; Povoa, Rui Manoel dos Santos

; Précoma, Dalton Bertolim

; Sousa, Antônio Carlos Sobral

; Dantas, João Miguel Malta

; Cesarino, Evandro José

; Barros e Silva, Pedro G. M. de

; Veiga Jardim, Paulo Cesar B.

; Lopes, Renato D.

International Journal of Cardiovascular Sciences

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2024, Volume 37 elocation e20220138

Resumo: En | Texto: En | PDF: En

Abstract Background In view of the high prevalence of hypertension and the importance of adequate drug therapy in the prevention of complications, it is necessary to know the adherence to drug treatment in this population. Objective To verify adherence to antihypertensive drug treatment in Brazilian patients with hypertension using the Morisky-Green Test (MGT), relating it with demographic data. Methods Prospective, observational, multicenter, national registry study, with 2,578 hypertensive patients participating in study I, the Brazilian Cardiovascular Registry of Arterial Hypertension (I-RBH), recruited in the five regions of Brazil. The analyses carried out on the data were descriptive statistics, qui-square tests, ANOVA, and logistic regression, adopting 5% as the significance level for the tests. Results The research shows that 56.13% of patients in the sample were female; 56.71% were elderly (≥ 65 years); 55.86% were White; 52.37% were from the Southeast Region; and 59.74% were non-adherent. Logistic regression showed an independent relationship between patients’ age, ethnicity, and region with medication adherence. Conclusion Adherence to treatment is the key to reducing high rates of cardiovascular complications. The study brings a successful outcome in the relationship between the factors ethnicity, age, and region of patients with hypertension and medication adherence. To this end, it is necessary to understand these factors, considering systematic evaluation in the care of patients with hypertension and other chronic non-communicable diseases. This study is a significant contribution to multidisciplinary teams, as it highlights which risk factors interfere with medication adherence, incorporating better strategies in health education. complications population MoriskyGreen Morisky Green MGT, MGT , (MGT) Prospective observational multicenter 2578 2 578 2,57 I IRBH, IRBH RBH (I-RBH) Brazil statistics quisquare qui square tests ANOVA 5 5613 56 13 56.13 female 5671 71 56.71 ≥ ( 6 years years) 5586 55 86 55.86 White 5237 52 37 52.37 Region 5974 59 74 59.74 nonadherent. nonadherent non adherent. adherent non-adherent age ethnicity end noncommunicable communicable diseases teams education (MGT 257 57 2,5 (I-RBH 561 1 56.1 567 7 56.7 558 8 55.8 523 3 52.3 597 59.7 25 2, 56. 55. 52. 59.

https://doi.org/10.36660/ijcs.20220138

Comentário a “Sobre el lugar que corresponde a Herbart en el psychologismusstreit” Sobre psychologismusstreit
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Brito, Evandro Oliveira de

Trans/Form/Ação

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2024, Volume 47 Nº 3 elocation e0240041

Resumo: Pt | Texto: Pt | PDF: Pt

https://doi.org/10.1590/0101-3173.2024.v47.n3.e0240041

Effectiveness of experimental dentifrices based on essential oils on biofilm on complete dentures: an in vitro study dentures
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dos Santos, Andrezza Cristina Moura

; Mendes, Filipe Santos Ferreira

; Pompeo, Fernanda Thaís

; Watanabe, Evandro

; Macedo, Ana Paula

; de Souza, Valéria Oliveira Pagnano

; Paranhos, Helena de Freitas Oliveira

; Silva-Lovato, Cláudia Helena

Journal of Applied Oral Science

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2024, Volume 32 elocation e20230397

Resumo: En | Texto: En | PDF: En

Abstract Specific products containing natural resources can contribute to the innovation of complete denture hygiene. Objective: To conduct an in vitro evaluation of experimental dentifrices containing essential oils of Bowdichia virgilioides Kunth (BvK), Copaifera officinalis (Co), Eucalyptus citriodora (Ec), Melaleuca alternifolia (Ma) and Pinus strobus (Ps) at 1%. Methodology: The variables evaluated were organoleptic and physicochemical characteristics, abrasiveness (mechanical brushing machine) simulating 2.5 years, and microbial load (Colony Forming Units - CFU/mL), metabolic activity (XTT assay) and cell viability (Live/Dead® BacLight™ kit) of the multispecies biofilm (Streptococcus mutans: Sm, Staphylococcus aureus: Sa, Candida albicans: Ca and Candida glabrata: Cg). Specimens of heat-polymerized acrylic resins (n=256) (n=96 specimens for abrasiveness, n=72 for microbial load count, n=72 for biofilm metabolic activity, n=16 for cell viability and total biofilm quantification) with formed biofilm were divided into eight groups for manual brushing (20 seconds) with a dental brush and distilled water (NC: negative control), Trihydral (PC: positive control), placebo (Pl), BvK, Co, Ec, Ma or Ps. After brushing, the specimens were washed with PBS and immersed in Letheen Broth medium, and the suspension was sown in solid specific medium. The organoleptic characteristics were presented by descriptive analysis. The values of density, pH, consistency and viscosity were presented in a table. The data were analyzed with the Wald test in a generalized linear model, followed by the Kruskal-Wallis test, Dunn's test (mass change) and the Bonferroni test (UFC and XTT). The Wald test in Generalized Estimating Equations and the Bonferroni test were used to analyze cell viability. Results: All dentifrices showed stable organoleptic characteristics and adequate physicochemical properties. CN, Ec, Ps, Pl and PC showed low abrasiveness. There was a significant difference between the groups (p<0.001) for microbial load, metabolic activity and biofilm viability. Conclusions: It was concluded that the BvK, Ec and Ps dentifrices are useful for cleaning complete dentures, as they have antimicrobial activity against biofilm. The dentifrices containing Bowdichia virgilioides Kunth showed medium abrasiveness and should be used with caution. hygiene Objective BvK , (BvK) Co (Co) (Ec) (Ma (Ps 1 1% Methodology mechanical machine 25 2 5 2. years Colony CFU/mL, CFUmL CFU/mL CFU mL CFU/mL) XTT assay Live/Dead® LiveDead Live Dead (Live/Dead BacLight kit Streptococcus mutans Sm aureus Sa albicans glabrata Cg. Cg . Cg) heatpolymerized heat polymerized n=256 n256 n 256 (n=256 n=96 n96 96 (n=9 n72 72 n=7 count n16 16 n=1 quantification 20 (2 seconds NC (NC control, control control) (PC Pl, (Pl) analysis density pH table model KruskalWallis Kruskal Wallis Dunns Dunn s mass change UFC XTT. XTT) Results properties CN p<0.001 p0001 p 0 001 (p<0.001 Conclusions dentures caution (BvK (Co (Ec Live/Dead n=25 n25 (n=25 n=9 n9 9 (n= n7 7 n= n1 ( (Pl p<0.00 p000 00 (p<0.00 n=2 n2 (n=2 (n p<0.0 p00 (p<0.0 p<0. p0 (p<0. p<0 (p<0 p< (p< (p

https://doi.org/10.1590/1678-7757-2023-0397

EFFECT OF DORMANCY ON THE EMERGENCE OF Tabernaemontana heterophylla SEEDLINGS IN DIFFERENT SUBSTRATES
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Pinheiro, Romário de Mesquita

; Carvalho, Henrique Pereira de

; Marques, Ricardo de Araújo

; Ferreira, Evandro José Linhares

; Gadotti, Gizele Ingrid

; Barros, Quétila Souza

; Rocha, Andrea Alechandre da

; Oliveira, Erica Karolina Barros de

Revista Árvore

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2024, Volume 48 elocation e4807

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT The composition and dynamics of plant communities are determined by the survival, dispersal and persistence of seeds in the soil, some of the fundamental aspects for understanding plant biology, among which seed dormancy is of particular importance. The aim of this work was to find out whether seed dormancy is affected by certain substrates in order to improve the production of Tabernaemontana heterophylla seedlings. Treatments were carried out with different substrates (T1. Sand, T2. Vegetable clay, T3. Vegetable clay + sand (1:1 ratio), T4. Vermiculite, T5. Cattle manure, T6. Sawdust and T7. Organic compost) in 7 x 4 factorial schemes, the results of which were subjected to an analysis of variance and a comparison of means with the Tukey test at a probability of 5%. The seeds with visible germination structure (hypocotyl) showed an apical meristem in a dormant stage. The number of normal seedlings did not exceed 25% of the germinated seeds in all treatments, with a high proportion of nonviable seeds observed. In the absence of technical information on overcome dormancy, it is important to use strategies that stimulate germination and subsequent seedling growth. The slow germination combined with the presence of dormancy in the hypocotyledon were factors that negatively affected the propagation of the species studied. survival soil biology importance T1. T1 T (T1 Sand T2 T3 11 1 (1: ratio, ratio , ratio) T4 Vermiculite T5 manure T6 T7 compost schemes 5 5% hypocotyl (hypocotyl stage 25 treatments observed growth studied (T (1 2 (

RESUMO A composição e a dinâmica das comunidades vegetais são determinadas pela sobrevivência, dispersão e persistência das sementes no solo, alguns dos aspectos fundamentais para a compreensão da biologia vegetal, entre os quais se destaca a dormência das sementes. O objetivo deste trabalho foi verificar se a dormência das sementes é afetada por determinados substratos, a fim de melhorar a produção de mudas de Tabernaemontana heterophylla. Os tratamentos foram realizados com diferentes substratos (T1. Areia, T2. Argila vegetal, T3. Argila vegetal + areia (proporção 1:1), T4. Vermiculita, T5. Estrume de gado, T6. Serragem e T7. Composto orgânico) em esquemas fatoriais 7 x 4, cujos resultados foram submetidos a uma análise de variância e a uma comparação de médias com o teste de Tukey a uma probabilidade de 5%. As sementes com estrutura germinativa visível (hipocótilo) apresentaram meristema apical em estado de dormência. O número de plântulas normais não ultrapassou 25% das sementes germinadas em todos os tratamentos, tendo sido observada uma elevada proporção de sementes inviáveis. Na ausência de informações técnicas sobre a superação da dormência, é importante utilizar estratégias que estimulem a germinação e o posterior crescimento das plântulas. A lenta germinação aliada à presença de dormência no hipocótilo foram fatores que afetaram negativamente a propagação da espécie estudada. sobrevivência solo heterophylla T1. T1 T (T1 Areia T2 T3 11, 11 1 , 1:1) T4 Vermiculita T5 gado T6 T7 orgânico 4 5 5% (hipocótilo 25 inviáveis estudada (T 1:1 2 1:

https://doi.org/10.53661/1806-9088202448263743

Diretriz sobre Diagnóstico e Tratamento da Cardiomiopatia Hipertrófica – 2024 202 20 2
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Fernandes, Fabio

; Simões, Marcus V.

; Correia, Edileide de Barros

; Marcondes-Braga, Fabiana Goulart

; Coelho-Filho, Otavio Rizzi

; Mesquita, Cláudio Tinoco

; Mathias Junior, Wilson

; Antunes, Murillo de Oliveira

; Arteaga-Fernández, Edmundo

; Rochitte, Carlos Eduardo

; Ramires, Felix José Alvarez

; Alves, Silvia Marinho Martins

; Montera, Marcelo Westerlund

; Lopes, Renato Delascio

; Oliveira Junior, Mucio Tavares de

; Scolari, Fernando Luis

; Avila, Walkiria Samuel

; Canesin, Manoel Fernandes

; Bocchi, Edimar Alcides

; Bacal, Fernando

; Moura, Lidia Zytynski

; Saad, Eduardo Benchimol

; Scanavacca, Mauricio Ibrahim

; Valdigem, Bruno Pereira

; Cano, Manuel Nicolas

; Abizaid, Alexandre Antonio Cunha

; Ribeiro, Henrique Barbosa

; Lemos Neto, Pedro Alves

; Ribeiro, Gustavo Calado de Aguiar

; Jatene, Fabio Biscegli

; Dias, Ricardo Ribeiro

; Beck-da-Silva, Luis

; Rohde, Luis Eduardo Paim

; Bittencourt, Marcelo Imbroinise

; Pereira, Alexandre da Costa

; Krieger, José Eduardo

; Villacorta Junior, Humberto

; Martins, Wolney de Andrade

; Figueiredo Neto, José Albuquerque de

; Cardoso, Juliano Novaes

; Pastore, Carlos Alberto

; Jatene, Ieda Biscegli

; Tanaka, Ana Cristina Sayuri

; Hotta, Viviane Tiemi

; Romano, Minna Moreira Dias

; Albuquerque, Denilson Campos de

; Mourilhe-Rocha, Ricardo

; Hajjar, Ludhmila Abrahão

; Brito Junior, Fabio Sandoli de

; Caramelli, Bruno

; Calderaro, Daniela

; Farsky, Pedro Silvio

; Colafranceschi, Alexandre Siciliano

; Pinto, Ibraim Masciarelli Francisco

; Vieira, Marcelo Luiz Campos

; Danzmann, Luiz Claudio

; Barberato, Silvio Henrique

; Mady, Charles

; Martinelli Filho, Martino

; Torbey, Ana Flavia Malheiros

; Schwartzmann, Pedro Vellosa

; Macedo, Ariane Vieira Scarlatelli

; Ferreira, Silvia Moreira Ayub

; Schmidt, Andre

; Melo, Marcelo Dantas Tavares de

; Lima Filho, Moysés Oliveira

; Sposito, Andrei C.

; Brito, Flávio de Souza

; Biolo, Andreia

; Madrini Junior, Vagner

; Rizk, Stephanie Itala

; Mesquita, Evandro Tinoco

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 Nº 7 elocation e202400415

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20240415

The impact of passion for exercising on the perception of well-being during periods of social isolation wellbeing well being
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Peixoto, Evandro Morais

; Campos, Carolina Rosa

; Oliveira, Karina da Silva

; Palma, Bartira Pereira

; Bonfá-Araujo, Bruno

; Anacleto, Geovana Mellisa Castrezana

Estudos de Psicologia (Campinas)

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2024, Volume 41 elocation e210022

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Verificar as associações entre as variáveis paixão, afetos, satisfação com a vida e distresse, o poder preditivo dos diferentes tipos de paixão sobre a percepção de afetos positivos e negativos, e o efeito desta relação frente a avaliação de bem-estar psicológico e distresse, partindo de um modelo teórico. Método Participaram 359 sujeitos, com idades entre 18 e 70 anos (M = 36,60; DP = 11,90) que responderam ao questionário sociodemográfico, Escalas de Paixão, Afetos Positivos e Negativos, Satisfação com a Vida e Distresse Psicológico de Kessler. Os dados foram analisados por meio de coeficientes de correlação e modelagem de equações estruturais. Resultados A adequação do modelo proposto foi verificada com índices ajustes satisfatórios e relações positivas entre Paixão Harmoniosa, Afetos Positivos e Satisfação com a Vida. Conclusão Os resultados sugerem que a Paixão Harmoniosa contribui para o enfrentamento do sofrimento e de experiências negativas, como os experimentados no momento pandêmico. distresse negativos bemestar bem estar teórico 35 sujeitos 1 7 M 36,60 3660 36 60 11,90 1190 11 90 sociodemográfico Negativos Kessler estruturais negativas pandêmico 3 36,6 366 6 11,9 119 9 36, 11,

Abstract Objective of this study was to, based on a theoretical model, verify the associations between the variables passion, affect, satisfaction with life, and distress, the predictive power of the different types of passion on the perception of positive and negative affect, and the effect of this relation against the evaluation of psychological well-being and distress. Method Three hundred and fifty-nine participants aged between 18 and 70 years (M = 36.60; SD = 11.90) answered a sociodemographic questionnaire, and the Passion, Positive and Negative Affect Schedule, Satisfaction with Life, and the Kessler Psychological Distress Scales. Data were analyzed using correlation coefficients and structural equation modeling. Results The adequacy of the proposed model was estimated with satisfactory fit indices and positive relations between Harmonious Passion, Positive Affect, and Satisfaction with Life. Conclusion The results suggest that Harmonious Passion contributes to coping with suffering and negative experiences, such as those experienced in the pandemic moment. affect life distress wellbeing well being fiftynine fifty nine 1 7 M 36.60 3660 36 60 11.90 1190 11 90 questionnaire Schedule Life Scales modeling experiences moment 36.6 366 3 6 11.9 119 9 36. 11.

https://doi.org/10.1590/1982-0275202441e210022

Quality of life associated with nursing professionals’ individual resources and work professionals
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Mallagoli, Isabela Saura Sartoreto

; Silva, Evandro Piccinelli da

; Oliveira, Maria Aline do Nascimento

; Barbosa, Italo Everton Bezerra

; Sampaio, Aristeia Nunes

; Matias, Aline Bicalho

; Barbosa, Dulce Aparecida

; Belasco, Angélica Gonçalves Silva

Revista Brasileira de Enfermagem

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2024, Volume 77 Nº 3 elocation e20230476

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN Objetivos: evaluar los componentes físicos y mentales de la calidad de vida de los profesionales de enfermería y asociarlos con características individuales, de salud y laborales. Métodos: investigación transversal, con profesionales de enfermería de un hospital universitario de São Paulo. Se aplicó cuestionario propio e instrumentos validados. Resultados: la calidad de vida general se vio comprometida. El componente físico fue menor en relación con bajos ingresos familiares y entre quienes percibieron mayor control/presión en el trabajo, y mejor para quienes practicaban actividad física y contaban con apoyo de la dirección y organización. El componente mental fue menor en los profesionales que refirieron insatisfacción con el trabajo, peor salud física autovalorada y mayor edad. Las puntuaciones de ambos componentes se redujeron debido a enfermedades relacionadas con el trabajo, peor capacidad laboral y aumento de la somnolencia diurna. Conclusiones: la calidad de vida se asoció estadísticamente con factores institucionales controlables y recursos individuales que, excepto la edad, pueden ser promovidos. Objetivos laborales Métodos transversal Paulo validados Resultados comprometida controlpresión control presión trabajo organización edad diurna Conclusiones promovidos

ABSTRACT Objectives: to assess the physical and mental components of nursing professionals’ quality of life and associate them with individual, health and work characteristics. Methods: cross-sectional research, with nursing professionals from a university hospital in São Paulo. Own questionnaire and validated instruments were applied. Results: the overall quality of life was compromised. The physical component was lower in relation to low family income and among those who perceived greater control/pressure at work, and better for those who practiced physical activity and had support of leader and organization. The mental component was lower in professionals who reported dissatisfaction with work, worse self-rated physical health and were older. Scores for both components reduced due to work-related illnesses, worse work ability and increased daytime sleepiness. Conclusions: quality of life was statistically associated with controllable institutional factors and individual resources that, except age, can be promoted. Objectives characteristics Methods crosssectional cross sectional research Paulo applied Results compromised controlpressure control pressure organization selfrated self rated older workrelated related illnesses sleepiness Conclusions that age promoted

RESUMO Objetivos: avaliar os componentes físico e mental da qualidade de vida de profissionais de enfermagem e associá-los às características individuais, de saúde e do trabalho. Métodos: pesquisa transversal, com profissionais de enfermagem de um hospital universitário de São Paulo. Aplicados questionário próprio e instrumentos validados. Resultados: a qualidade de vida geral mostrou-se comprometida. O componente físico foi menor em relação à baixa renda familiar e entre os que percebiam maior controle/pressão no trabalho, e melhor para quem praticava atividade física e tinha apoio da chefia e organização. O componente mental foi menor nos profissionais que referiram insatisfação com o trabalho, pior autoavaliação de saúde física e com idade elevada. Escores de ambos componentes reduziram mediante doenças relacionadas ao trabalho, pior capacidade para o trabalho e aumento da sonolência diurna. Conclusões: a qualidade de vida foi estatisticamente associada a fatores institucionais controláveis e recursos individuais que, exceto idade, podem ser promovidos. Objetivos associálos associá los Métodos transversal Paulo validados Resultados mostrouse mostrou se comprometida controlepressão controle pressão organização elevada diurna Conclusões promovidos

https://doi.org/10.1590/0034-7167-2023-0476

Physical characteristics of the hair coat of sows raised in free-range systems in a tropical environment freerange free range
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Nascimento, Sheila Tavares

; Mós, João Victor do Nascimento

; Murata, Luci Sayori

; Santos, Vinicius Machado dos

; Steidle Neto, Antonio José

; Oliveira, Evandro Menezes de

; Maia, Alex Sandro Campos

; Teixeira, Bruno Emanoel

; Parizotto, Raquel

; Silva, Luana Freitas

Acta Scientiarum. Animal Sciences

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2024, Volume 46 elocation e63533

Resumo: En | Texto: En | PDF: En

ABSTRACT. The aim of this study was to investigate the hair coat characteristics of sows raised in a free-range system in a tropical climate and assess associations with effective radiative properties and thermal conductivity. Bristles were collected from December 2017 to April 2018 and evaluated for diameter (mm), length (mm), and density (bristles per cm2). From these data, the effective thermal conductivity, absorptivity, transmissivity, and reflectivity of the hair coat were determined. Sows were separated into four groups according to skin pigmentation and color parameters. The environment was characterized with regard to average air temperature (°C), relative humidity (%), and shortwave radiation (W m-2). The data were analyzed by repeated measures analysis. Bristle length (33 mm) and density (10 bristles cm-2) were lower in summer than in colder months (48 mm and 20 bristles cm-2, respectively). Effective absorptivity was higher and transmittance was lower in more pigmented sows, demonstrating a connection with protection against solar radiation. Therefore, the combination of a pigmented and dense coat seems to be ideal for pigs reared in free-range systems. ABSTRACT freerange free range conductivity 201 mm, , (mm) cm2. cm2 cm . cm2) transmissivity determined parameters °C, C °C (°C) %, % (%) W m2. m2 m 2 m-2) analysis 33 (3 10 (1 cm-2 48 (4 cm2, 2, respectively. respectively respectively) Therefore systems (mm (°C (% m-2 3 ( 1 cm- 4 m-

https://doi.org/10.4025/actascianimsci.v46i1.63533

10.

II Brazilian Society of Rheumatology consensus for lupus nephritis diagnosis and treatment
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Reis-Neto, Edgard Torres dos

; Seguro, Luciana Parente Costa

; Sato, Emília Inoue

; Borba, Eduardo Ferreira

; Klumb, Evandro Mendes

; Costallat, Lilian Tereza Lavras

; Medeiros, Marta Maria das Chagas

; Bonfá, Eloisa

; Araújo, Nafice Costa

; Appenzeller, Simone

; Montandon, Ana Carolina de Oliveira e Silva

; Yuki, Emily Figueiredo Neves

; Teixeira, Roberto Cordeiro de Andrade

; Telles, Rosa Weiss

; Egypto, Danielle Christinne Soares do

; Ribeiro, Francinne Machado

; Gasparin, Andrese Aline

; Araujo Junior, Antonio Silaide de

; Neiva, Cláudia Lopes Santoro

; Calderaro, Debora Cerqueira

; Monticielo, Odirlei Andre

Advances in Rheumatology

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2024, Volume 64 elocation 48

Resumo: En | Texto: En | PDF: En

Abstract Objective To develop the second evidence-based Brazilian Society of Rheumatology consensus for diagnosis and treatment of lupus nephritis (LN). Methods Two methodologists and 20 rheumatologists from Lupus Comittee of Brazilian Society of Rheumatology participate in the development of this guideline. Fourteen PICO questions were defined and a systematic review was performed. Eligible randomized controlled trials were analyzed regarding complete renal remission, partial renal remission, serum creatinine, proteinuria, serum creatinine doubling, progression to end-stage renal disease, renal relapse, and severe adverse events (infections and mortality). The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to develop these recommendations. Recommendations required ≥82% of agreement among the voting members and were classified as strongly in favor, weakly in favor, conditional, weakly against or strongly against a particular intervention. Other aspects of LN management (diagnosis, general principles of treatment, treatment of comorbidities and refractory cases) were evaluated through literature review and expert opinion. Results All SLE patients should undergo creatinine and urinalysis tests to assess renal involvement. Kidney biopsy is considered the gold standard for diagnosing LN but, if it is not available or there is a contraindication to the procedure, therapeutic decisions should be based on clinical and laboratory parameters. Fourteen recommendations were developed. Target Renal response (TRR) was defined as improvement or maintenance of renal function (±10% at baseline of treatment) combined with a decrease in 24-h proteinuria or 24-h UPCR of 25% at 3 months, a decrease of 50% at 6 months, and proteinuria < 0.8 g/24 h at 12 months. Hydroxychloroquine should be prescribed to all SLE patients, except in cases of contraindication. Glucocorticoids should be used at the lowest dose and for the minimal necessary period. In class III or IV (±V), mycophenolate (MMF), cyclophosphamide, MMF plus tacrolimus (TAC), MMF plus belimumab or TAC can be used as induction therapy. For maintenance therapy, MMF or azathioprine (AZA) are the first choice and TAC or cyclosporin or leflunomide can be used in patients who cannot use MMF or AZA. Rituximab can be prescribed in cases of refractory disease. In cases of failure in achieving TRR, it is important to assess adherence, immunosuppressant dosage, adjuvant therapy, comorbidities, and consider biopsy/rebiopsy. Conclusion This consensus provides evidence-based data to guide LN diagnosis and treatment, supporting the development of public and supplementary health policies in Brazil. evidencebased evidence LN. . (LN) 2 guideline performed remission doubling endstage end stage disease relapse infections mortality. mortality mortality) Assessment GRADE (GRADE 82 ≥82 favor conditional intervention diagnosis, (diagnosis opinion involvement but procedure parameters developed TRR (TRR ±10% 10 (±10 24h 24 25 months 50 08 0 8 0. g24 g g/2 1 period ±V, V ±V , (±V) MMF, (MMF) cyclophosphamide TAC, (TAC) therapy AZA (AZA adherence dosage biopsyrebiopsy rebiopsy biopsy/rebiopsy Brazil (LN ≥8 ±10 (±1 5 g2 g/ (±V (MMF (TAC ≥ ±1 (± ± (

https://doi.org/10.1186/s42358-024-00386-8

11.

Influence of killer immunoglobulin-like receptors genes on the recurrence rate of ocular toxoplasmosis in Brazil immunoglobulinlike immunoglobulin like
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Perce-da-Silva, Daiana de Souza

; Joaquim, Thays Euzebio

; Aleixo, Ana Luisa Quintella do Couto

; Motta, Juliana Pessanha Rodrigues

; Lima-Junior, Josué da Costa

; Ribeiro-Alves, Marcelo

; de Oliveira-Ferreira, Joseli

; Porto, Luís Cristóvão de Moraes Sobrino

; Banic, Dalma Maria

; Amendoeira, Maria Regina Reis

Memórias do Instituto Oswaldo Cruz

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2023, Volume 118 elocation e220203

Resumo: En | Texto: En | PDF: En

BACKGROUND Recurrence is a hallmark of ocular toxoplasmosis (OT), and conditions that influence its occurrence remain a challenge. Natural killer cells (NK) are effectors cells whose primary is cytotoxic function against many parasites, including Toxoplasma gondii. Among the NK cell receptors, immunoglobulin-like receptors (KIR) deserve attention due to their high polymorphism. OBJECTIVES This study aimed to analyse the influence of KIR gene polymorphism in the course of OT infection and its association with recurrences after an active episode. METHODS Ninety-six patients from the Ophthalmologic Clinic of the National Institute of Infectology Evandro Chagas were followed for up to five years. After DNA extraction, genotyping of the patients was performed by polymerase chain reaction sequence-specific oligonucleotide (PCR-SSO) utilising Luminex equipment for reading. During follow-up, 60.4% had a recurrence. FINDINGS We identified 25 KIR genotypes and found a higher frequency of genotype 1 (31.7%) with worldwide distribution. We note that the KIR2DL2 inhibitor gene and the gene activator KIR2DS2 were more frequent in patients without recurrence. Additionally, we observed that individuals who carry these genes progressed recurrence episodes slowly compared to individuals who do not carry these genes. MAIN CONCLUSIONS The KIR2DL2 and KIR2DS2 are associated as possible protection markers against ocular toxoplasmosis recurrence (OTR). OT, , (OT) challenge (NK parasites gondii immunoglobulinlike immunoglobulin like (KIR episode Ninetysix Ninety six years extraction sequencespecific sequence specific PCRSSO PCR SSO (PCR-SSO reading followup, followup follow up, follow-up 604 60 4 60.4 2 31.7% 317 31 7 (31.7% distribution KIRDL DL KIR2DL KIRDS DS KIR2DS Additionally OTR. OTR . (OTR) (OT 6 60. 31.7 3 (31.7 (OTR 31. (31. (31 (3 (

https://doi.org/10.1590/0074-02760220203

12.

Ammonia volatilization and nitrogen status in second-season corn after lime and gypsum application in no-till secondseason second season notill no till
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Minato, Evandro Antonio

; Besen, Marcos Renan

; Esper Neto, Michel

; Cassim, Bruno Maia Abdo Rahmen

; Zampar, Éder Júnior de Oliveira

; Inoue, Tadeu Takeyoshi

; Batista, Marcelo Augusto

Acta Scientiarum. Agronomy

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2023, Volume 45 elocation e58774

Resumo: En | Texto: En | PDF: En

ABSTRACT. In no-till (NT), liming and urea fertilization are performed on the soil surface, which can increase nitrogen (N) losses via ammonia volatilization. On the basis of N fertilization management, gypsum application provides a promising alternative for improving N uptake by plants. Therefore, the objective of this study was to evaluate the N behavior loss by NH3-N volatilization, the soil pH at a depth of 0 - 0.05 m, leaf N content, and N uptake by second-season corn after lime and gypsum application in a Rhodic Ferralsol under NT. Overall, the treatments consisted of a 4 × 4 factorial arrangement with four lime rates (0, 2.6, 5.4, and 8.1 Mg ha-1) and four gypsum rates (0, 4, 8, and 12 Mg ha-1). During the study period, second-season corn was cultivated for two years and fertilized with urea, for which the N losses through ammonia volatilization, soil pH, leaf N content, and N uptake values were quantified. The losses through ammonia volatilization were subjected to nonlinear regression using a logistic model, and the other variables were subjected to linear regressions. The lime applied by broadcasting on the soil surface in the NT increased the pH of the topsoil and increased N losses via NH3-N volatilization in the second-season corn. Further, the N losses in the NT treated with lime accounted for 58% of the applied N, which increased by 2.3 to 2.5% for each Mg ha-1 of lime applied. Therefore, lime or gypsum application did not improve the status of N in second-season corn in soils with low acidity and no S deficiency. ABSTRACT notill till NT, , (NT) (N management plants Therefore NH3N NHN NH3 NH 005 05 0.0 m content secondseason second season Overall 0, (0 26 2 6 2.6 54 5 5.4 81 8 1 8. ha1 ha ha1. . period quantified model regressions Further 58 23 3 2. 25 2.5 ha- deficiency (NT 00 0. ( 5.

https://doi.org/10.4025/actasciagron.v45i1.58774

13.

Spontaneous intracranial hypotension: from cerebral venous thrombosis to neurosurgical treatment: a case series experience from a Brazilian tertiary health care center hypotension treatment
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Moreira, Daniel Gabay

; Félix, Evandro Penteado Villar

; Onishi, Franz Jooji

; Ferraz, Henrique Ballalai

; Coradine, Tácio Luis Cavalcante

; Braga, Vinícius Lopes

; Oliveira, Enedina Maria Lobato de

Arquivos de Neuro-Psiquiatria

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2023, Volume 81 Nº 2 Páginas 128 - 133

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background Spontaneous intracranial hypotension (SIH) is a secondary cause of headache and an underdiagnosed disease. The clinical presentation can be highly variable. It typically presents with isolated classic orthostatic headache complaints, but patients can develop significant complications such as cerebral venous thrombosis (CVT). Objective To report 3 cases of SIH diagnosis admitted and treated in a tertiary-level neurology ward. Methods Review of the medical files of three patients and description of clinical and surgical outcomes. Results Three female patients with SIH with a mean age of 25.6 ± 10.0 years old. The patients had orthostatic headache, and one of them presented with somnolence and diplopia because of a CVT. Brain magnetic resonance imaging (MRI) ranges from normal findings to classic findings of SIH as pachymeningeal enhancement and downward displacement of the cerebellar tonsils. Spine MRI showed abnormal epidural fluid collections in all cases, and computed tomography (CT) myelography could determine an identifiable cerebrospinal fluid (CSF) leak in only one patient. One patient received a conservative approach, and the other two were submitted to open surgery with lamino-plasty. Both of them had uneventful recovery and remission in surgery follow-up. Conclusion The diagnosis and management of SIH are still a challenge in neurology practice. We highlight in the present study severe cases of incapacitating SIH, complication with CVT, and good outcomes with neurosurgical treatment. (SIH disease variable complaints CVT . (CVT) tertiarylevel tertiary level ward 256 25 6 25. 100 10 0 10. old (MRI tonsils CT (CT CSF (CSF approach laminoplasty. laminoplasty lamino plasty. plasty lamino-plasty followup. followup follow up. up follow-up practice treatment (CVT 2 1

Resumo Antecedentes Hipotensão intracraniana espontânea (HIE) é uma causa secundária de cefaleia e uma doença subdiagnosticada. A apresentação clínica pode ser muito variável. Tipicamente, se apresenta com queixas isoladas de cefaleia ortostática clássica, porém pode evoluir com complicações significativas como trombose venosa cerebral (TVC). Objetivo Relatar 3 casos de diagnóstico de hipotensão intracraniana espontânea manejados em uma enfermaria de neurologia de nível terciário. Métodos Revisão dos prontuários de três pacientes e descrição dos resultados clínicos e cirúrgicos. Resultados Três pacientes do sexo feminino com média de idade de 25.6 ± 10.0 anos. As pacientes apresentavam cefaleia ortostática e uma delas apresentou sonolência e diplopia devido a TVC. A ressonância magnética (RM) do encéfalo varia de achados normais até achados clássicos de HIE como realce paquimeníngeo e deslocamento inferior das tonsilas cerebelares. A RM da coluna mostrou coleções anormais de líquido epidural em todos os casos e a mielografia por tomografia computadorizada (TC) foi capaz de determinar fístula liquórica identificável em apenas uma paciente. Uma paciente recebeu abordagem conservadora e as outras duas foram submetidas a cirurgia aberta com laminoplastia. Ambas tiveram recuperação e remissão sem intercorrências no seguimento cirúrgico. Conclusão O diagnóstico e manejo da hipotensão intracraniana ainda são desafios na prática neurológica. Destacamos no presente estudo casos graves, complicação com TVC e bons resultados com tratamento neurocirúrgico. (HIE subdiagnosticada variável Tipicamente clássica . (TVC) terciário cirúrgicos 256 25 6 25. 100 10 0 10. anos (RM cerebelares TC (TC laminoplastia cirúrgico neurológica graves neurocirúrgico (TVC 2 1

https://doi.org/10.1055/s-0042-1758752

14.

Panorama das Intervenções Coronárias Percutâneas em Oclusões Totais Crônicas em Centros Participantes do LATAM CTO Registry no Brasil
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Silva, Antonio Carlos Botelho da

; Paula, João Eduardo Tinoco de

; Campos, Carlos M.

; Ribeiro, Marcelo Harada

; Martins Filho, Evandro

; Oliveira, Marcos Danillo Peixoto

; Côrtes, Leandro Assumpção

; Abelin, Aníbal Pereira

; Zukowski, Cleverson Neves

; Martinelli, Gustavo Cervino

; Brito, Fábio Sândoli de

; Muniz, Antônio José

; Cantarelli, Marcelo José de Carvalho

; Andrade, Pedro Beraldo de

; Medeiros, César Rocha

; Falcão, Breno de Alencar Araripe

; Fuchs, Felipe Costa

; Silva, Leonardo Sinnott

; Fattah, Tammuz

; Degrazia, Ramiro Caldas

; Mangione, José Armando

; Bezerra, Cristiano Guedes

; Baradel, Sandra

; Silveira, João Brum

; Ybarra, Luiz Fernando

; Weillenmann, Daniel

; Gottschall, Carlos

; Lemke, Viviana

; Silva, Franciele Rosa da

; Schmidt, Marcia Moura

; Belli, Karlyse Claudino

; Oliveira, Pedro Piccaro de

; Quadros, Alexandre Schaan de

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 Nº 4 elocation e20210462

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background Major advances have been seen in techniques and devices for performing percutaneous coronary interventions (PCIs) for chronic total occlusions (CTOs), but there are limited real-world practice data from developing countries. Objectives To report clinical and angiographic characteristics, procedural aspects, and clinical outcomes of CTO PCI performed at dedicated centers in Brazil. Methods Included patients underwent CTO PCI at centers participating in the LATAM CTO Registry, a Latin American multicenter registry dedicated to prospective collection of these data. Inclusion criteria were procedures performed in Brazil, age 18 years or over, and presence of CTO with PCI attempt. CTO was defined as a 100% lesion in an epicardial coronary artery, known or estimated to have lasted at least 3 months. Results Data on 1196 CTO PCIs were included. Procedures were performed primarily for angina control (85%) and/or treatment of moderate/severe ischemia (24%). Technical success rate was 84%, being achieved with antegrade wire approaches in 81% of procedures, antegrade dissection and re-entry in 9%, and retrograde approaches in 10%. In-hospital adverse cardiovascular events occurred in 2.3% of cases, with a mortality rate of 0.75%. Conclusions CTOs can be treated effectively in Brazil by using PCI, with low complication rates. The scientific and technological development observed in this area in the past decade is reflected in the clinical practice of dedicated Brazilian centers. (PCIs CTOs, , (CTOs) realworld real world countries characteristics aspects Registry 1 over attempt 100 artery months 119 included 85% 85 (85% andor moderatesevere moderate severe 24%. 24 24% . (24%) 84 84% 81 reentry re entry 9 9% 10 10% Inhospital In hospital 23 2 2.3 cases 075 0 75 0.75% rates (CTOs 11 8 (85 (24% 2. 07 7 0.75 (8 (24 0.7 ( (2 0.

Resumo Fundamento Tem sido observado um grande avanço nas técnicas e nos dispositivos para a realização de intervenções coronárias percutâneas (ICP) em oclusões totais coronarianas crônicas (OTC), mas existem poucos dados da prática do mundo real em países em desenvolvimento. Objetivos Relatar as características clínicas e angiográficas, os aspectos dos procedimentos e os resultados clínicos da ICP de OTC em centros dedicados a esse procedimento no Brasil. Métodos Os pacientes incluídos foram submetidos à ICP de OTC em centros participantes do LATAM CTO Registry, um registro multicêntrico latino-americano dedicado à coleta prospectiva desses dados. Os critérios de inclusão foram procedimentos realizados no Brasil, idade acima de 18 anos e presença de OTC com tentativa de ICP. A definição de OTC foi lesão de 100% em uma artéria coronária epicárdica, conhecida ou estimada como tendo pelo menos 3 meses de evolução. Resultados Foram incluídos dados de 1.196 ICPs de OTC. Os procedimentos foram realizados principalmente para controle da angina (85%) e/ou tratamento de uma grande área isquêmica (24%). A taxa de sucesso técnico foi de 84% e foi alcançada com técnicas de fios anterógrados em 81%, dissecção/reentrada anterógrada em 9% e retrógrada em 10% dos procedimentos. Os eventos cardiovasculares adversos intra-hospitalares ocorreram em 2,3% dos casos, sendo a mortalidade de 0,75%. Conclusões As OTC podem ser tratadas no Brasil por intervenção coronária percutânea de forma efetiva e com baixas taxas de complicações. O desenvolvimento científico e tecnológico observado nessa área na última década reflete-se na prática clínica de centros brasileiros dedicados a essa técnica. (ICP OTC, , (OTC) angiográficas Registry latinoamericano latino americano 1 100 epicárdica evolução 1196 196 1.19 85% 85 (85% eou 24%. 24 24% . (24%) 84 81 81% dissecçãoreentrada dissecção reentrada 9 10 intrahospitalares intra hospitalares 23 2 2,3 casos 075 0 75 0,75% complicações refletese reflete se técnica (OTC 119 19 1.1 8 (85 (24% 2, 07 7 0,75 11 1. (8 (24 0,7 ( (2 0,

https://doi.org/10.36660/abc.20210462

15.

Effect of solar radiation on Holstein heifers’ physiological variables and grazing behavior heifers
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Pereira, Ana Flávia Brunheira

; Silva, Mariana Letícia Gil

; Oliveira, Evandro Menezes de

; Nascimento, Sheila Tavares

; Toledo, Juliana Beatriz

Acta Scientiarum. Animal Sciences

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2023, Volume 45 elocation e59307

Resumo: En | Texto: En | PDF: En

ABSTRACT. The objective was to assess the physiological and behavioral variables of pasture-raised Holstein heifers on the basis of their coat color. Eight heifers were used, four with black coat, and four with white coat. In the morning and afternoon periods, their physiological variables were measured, namely respiratory rate (RR, mov min. -1), rectal temperature (TR, ºC), and coat surface temperature (TS, ºC). The behavior analysis considered the site (sun or shade), position (standing or lying down), and activities (idleness, rumination, grazing, and others). The data of the physiological variables were assessed through analysis of variance, and significance, through Tukey’s test at 5%, while behavioral data were assessed using the Chi-squared test (SAS Software). There was a difference for all of the heifers’ physiological variables as a function of coat color (p < 0.0001) and period (p < 0.0001), with black ones showing greater results than white ones as to all physiological variables in the afternoon period (p < 0.0001). Grazing behavior is reduced during the hottest hours of the day. We conclude that solar radiation changes the physiological variables and grazing behavior of pasture-raised Holstein heifers. ABSTRACT pastureraised pasture raised used periods measured RR, RR (RR min 1, 1 , -1) TR, TR (TR ºC, ºC ºC) TS, TS (TS ºC. . sun shade, shade shade) standing down, down down) idleness, idleness (idleness rumination others. others others) variance significance Tukeys Tukey s 5 5% Chisquared Chi squared SAS Software. Software Software) p 0.0001 00001 0 0001 0.0001, 0.0001. day -1 0.000 0000 000 - 0.00 00 0.0 0.

https://doi.org/10.4025/actascianimsci.v45i1.59307

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