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Disparidades sociodemográficas no câncer colorretal no Brasil, 1990-2019
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Schaedler, Anelise Camila
; Veloso, Guilherme Augusto
; Iser, Betine Pinto Moehlecke
; Malta, Deborah Carvalho
; Curado, Maria Paula
; Oliveira, Max Moura de
.
ABSTRACT In the world, colorectal cancer presents high rates of incidence and mortality, with differences according to the level of sociodemographic development. The objective of this study was to analyze the sociodemographic disparities of colorectal cancer in the Brazilian population aged 30 and older. This is a time series study of incidence, mortality, disability-adjusted life years (DALY), and prevalence, by sex, in Brazil and its Federal Units (FU) states from 1990 to 2019. The trend was estimated using Joinpoint regression analysis, and the Socio-Demographic Index (SDI) was used in the correlation analysis. The data analyzed were estimated by the Global Burden of Diseases Study 19. In Brazil and its states, the highest rates of these indicators were observed in males, with an increasing trend in both sexes. There was a positive association between SDI and all the analyzed indicators except for DALY in men. The differences in rates and trends between the states reflect the country’s development processes, such as urbanization and industrialization. More developed states have high rates with stable trends, while less developed states exhibit the opposite behavior, suggesting improved access to healthcare services and diagnosis.
RESUMO No mundo, o câncer colorretal apresenta altas taxas de incidência e mortalidade, com diferenças segundo nível de desenvolvimento sociodemográfico. O objetivo foi analisar as disparidades sociodemográficas do câncer colorretal na população brasileira com 30 anos ou mais. Trata-se de estudo de série temporal da incidência, mortalidade, Anos de Vida Ajustados por Incapacidade (Disability Adjusted Life Years – DALY) e prevalência, segundo sexo, no Brasil e nas Unidades da Federação (UF) de 1990 a 2019. A tendência foi estimada pela regressão de Joinpoint, e o índice sociodemográfico (SDI – Socio-Demographic Index) foi utilizado na análise de correlação. Os dados analisados foram estimados pelo Global Burden of Diseases Study 19. No Brasil e nas UF, as maiores taxas dos indicadores foram observadas no sexo masculino, com tendência de aumento em ambos os sexos. Houve associação positiva entre o SDI e todos os indicadores analisados, exceto para DALY em homens. As diferenças nas taxas e tendências entre as UF parecem refletir os processos de desenvolvimento do País, tais como urbanização e industrialização, em que as UF mais desenvolvidas possuem taxas elevadas com tendências de estabilidade, e as UF em desenvolvimento, com comportamento inverso, sugerindo melhorias de acesso aos serviços de saúde e diagnósticos.
2.
Disparidades sociodemográficas no câncer colorretal no Brasil, 1990-2019 Brasil 19902019 1990 2019 1990-201 1990201 199 201 1990-20 199020 19 20 1990-2 19902 1 2 1990-
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Schaedler, Anelise Camila
; Veloso, Guilherme Augusto
; Iser, Betine Pinto Moehlecke
; Malta, Deborah Carvalho
; Curado, Maria Paula
; Oliveira, Max Moura de
.
RESUMO No mundo, o câncer colorretal apresenta altas taxas de incidência e mortalidade, com diferenças segundo nível de desenvolvimento sociodemográfico. O objetivo foi analisar as disparidades sociodemográficas do câncer colorretal na população brasileira com 30 anos ou mais. Trata-se de estudo de série temporal da incidência, mortalidade, Anos de Vida Ajustados por Incapacidade (Disability Adjusted Life Years – DALY) e prevalência, segundo sexo, no Brasil e nas Unidades da Federação (UF) de 1990 a 2019. A tendência foi estimada pela regressão de Joinpoint, e o índice sociodemográfico (SDI – Socio-Demographic Index) foi utilizado na análise de correlação. Os dados analisados foram estimados pelo Global Burden of Diseases Study 19. No Brasil e nas UF, as maiores taxas dos indicadores foram observadas no sexo masculino, com tendência de aumento em ambos os sexos. Houve associação positiva entre o SDI e todos os indicadores analisados, exceto para DALY em homens. As diferenças nas taxas e tendências entre as UF parecem refletir os processos de desenvolvimento do País, tais como urbanização e industrialização, em que as UF mais desenvolvidas possuem taxas elevadas com tendências de estabilidade, e as UF em desenvolvimento, com comportamento inverso, sugerindo melhorias de acesso aos serviços de saúde e diagnósticos. mundo mortalidade 3 Tratase Trata se Disability prevalência (UF 199 2019 Joinpoint SocioDemographic Socio Demographic Index correlação 19 masculino sexos homens País industrialização estabilidade inverso diagnósticos 201 1 20 2
ABSTRACT In the world, colorectal cancer presents high rates of incidence and mortality, with differences according to the level of sociodemographic development. The objective of this study was to analyze the sociodemographic disparities of colorectal cancer in the Brazilian population aged 30 and older. This is a time series study of incidence, mortality, disability-adjusted life years (DALY), and prevalence, by sex, in Brazil and its Federal Units (FU) states from 1990 to 2019. The trend was estimated using Joinpoint regression analysis, and the Socio-Demographic Index (SDI) was used in the correlation analysis. The data analyzed were estimated by the Global Burden of Diseases Study 19. In Brazil and its states, the highest rates of these indicators were observed in males, with an increasing trend in both sexes. There was a positive association between SDI and all the analyzed indicators except for DALY in men. The differences in rates and trends between the states reflect the country’s development processes, such as urbanization and industrialization. More developed states have high rates with stable trends, while less developed states exhibit the opposite behavior, suggesting improved access to healthcare services and diagnosis. world mortality 3 older disabilityadjusted disability adjusted DALY, , (DALY) prevalence sex FU (FU 199 2019 analysis SocioDemographic Socio Demographic (SDI 19 males sexes men countrys country s processes industrialization behavior diagnosis (DALY 201 1 20 2
3.
The high biodiversity of benthic organisms in a coastal ecosystem revealed by an integrative approach
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Amaral, A. Cecília Z.
; Cunha, Beatriz P.
; Checon, Helio H.
; Godoy, Angélica S. de
; Silva, Camila F. da
; Corte, Guilherme N.
; Nogueira, João M. de M.
; Fukuda, Marcelo V.
; Steiner, Tatiana M.
; Kawauchi, Gisele Y.
; Turra, Alexander
; Denadai, Márcia R.
; Ferreira, Luciane
; Mendonça, Joel B. de
; Tavares, Marcos
; Leite, Fosca P. P.
; Costa, Mariana F. B.
; Siqueira, Silvana G. L.
; Vieira, Leandro M.
; Dias, Gustavo M.
; Teixeira, Joyce A.
; Rocha, Rosana M.
; Gusmão, Luciana C.
; Borges, Michela
; Alitto, Renata
; Machado, Fabrizio M.
; Passos, Flávio D.
; Cunha, Carlo M.
; Simone, Luiz R.L.
; Araujo, Ana Paula G.
; Carbayo, Fernando
; Bahia, Juliana
; Bulnes, Verónica N.
; Castello-Branco, Cristiana
; Hajdu, Eduardo
; Vilas-Boas, Ana Carolina
; Garraffoni, André R. S.
; Schockaert, Ernest
; Fonseca, Gustavo
; Domenico, Maikon Di
; Curini-Galletti, Marco
; Sørensen, Martin V.
; Hochberg, Rick
; Oliveira, Ana Julia F. C. de
; Zampieri, Bruna Del B.
; Chinelatto, Roberta M.
; Migotto, Alvaro E.
.
Resumo O aumento da modificação dos habitats e da perda de espécies demanda esforços consistentes para descrever e compreender os padrões de biodiversidade. O programa BIOTA/FAPESP foi criado nesse contexto e é uma iniciativa de sucesso para promover estudos em biodiversidade e conservação no Brasil. O BIOTA/Araçá é um projeto interdisciplinar que promoveu uma avaliação detalhada da biodiversidade da Baía do Araçá, um ecossistema costeiro localizado ao Norte do estado de São Paulo, Sudeste do Brasil. A baía engloba múltiplos habitats, tais como praias, manguezais, costões rochosos, e uma planície de maré, e também fornece importantes serviços ecossistêmicos. Infelizmente, a baía está sujeita à conflitos sócio-ambientais complexos que contrastam demandas econômicas, sociais e ambientais (i.e. a expansão das atividades do porto vizinho vs. a pesca artesanal de pequena escala e a proteção da biodiversidade). O presente estudo apresenta um levantamento das espécies bentônicas que ocorrem nos diferentes habitats da Baía do Araçá, incluindo dados obtidos durante o projeto BIOTA/Araçá e de investigações realizadas anteriormente na área. As espécies bentônicas desempenham um papel importante no ambiente marinho, e estudar a diversidade desses organismos que vivem associados ao fundo é indispensável para compreender o funcionamento do meio ambiente. A macrofauna, meiofauna, e microorganismos associados aos fundos consolidado e inconsolidado foram listados, e informações adicionais foram fornecidas para cada espécie, tais como a distribuição geográfica e nos habitats. O checklist inclui 826 espécies, quase 70% registradas durante o projeto BIOTA/Araçá. Os taxa mais especiosos foram os anelídeos (225 spp.), moluscos (194 spp.), e crustáceos (177 spp.). Entre as espécies bentônicas listadas, sete são endêmicas da Baía do Araçá, 14 são consideradas ameaçadas de extinção, e sete são exploradas economicamente. A baía é a localidade tipo de vários taxa, e 11 novas espécies bentônicas foram descritas com base em espécimes amostrados durante o projeto. Este projeto mostra a importância da Baía do Araçá como um ambiente de riqueza biológica única e demonstra a necessidade de esforços para a sua conservação considerando as atuais ameaças. BIOTAFAPESP BIOTA FAPESP Brasil BIOTAAraçá Paulo praias manguezais rochosos maré ecossistêmicos Infelizmente sócioambientais sócio econômicas i.e. ie i (i.e vs . biodiversidade) área marinho macrofauna meiofauna listados espécie 82 70 225 (22 spp., spp spp. , spp.) 194 (19 177 (17 spp.. listadas 1 extinção economicamente ameaças i.e 8 7 22 (2 19 (1 17 2 (
Abstract Increasing habitat modification and species loss demand consistent efforts to describe and understand biodiversity patterns. The BIOTA/FAPESP Program was created in this context and it has been a successful initiative to promote studies on biodiversity and conservation in Brazil. The BIOTA/Araçá is an interdisciplinary project that provided a detailed evaluation of the biodiversity of Araçá Bay, a coastal seascape located on the North coast of the state of São Paulo, Southeast Brazil. The bay encompasses multiple habitats, such as beaches, mangroves, rocky shores, and a tidal flat, and provides important ecosystem services. Unfortunately, the bay is the subject of complex social-environmental conflicts that oppose economic, social, and environmental demands (i.e., the expansion of neighboring harbor activities vs. small-scale artisanal fisheries and protection of biodiversity). The present study presents a survey of the benthic species occurring in the different habitats of Araçá Bay, including data obtained during the BIOTA/Araçá project and previous assessments of the area. The benthic species play an important role in marine environments and studying the diversity of these organisms that live associated with the bottom is indispensable for comprehending the environment’s functioning. The macrofauna, meiofauna, and microorganisms associated with soft and hard bottom were listed, and additional information, such as the habitat and geographical distribution, were provided for each species. The checklist includes 826 species, almost 70% recorded during the BIOTA/Araçá project. The most speciose taxa were the annelids (225 spp.), mollusks (194 spp.), and crustaceans (177 spp.). Seven benthic species are endemic to Araçá Bay, 14 are considered threatened, and seven are economically exploited. Furthermore, the bay is the type locality of many taxa, and 11 new benthic species were described based on specimens sampled during the project. This project shows the importance of Araçá Bay as a unique biologically rich environment and highlights the need for conservation efforts in light of the current threats. patterns BIOTAFAPESP BIOTA FAPESP Brazil BIOTAAraçá Paulo beaches mangroves shores flat services Unfortunately socialenvironmental social economic i.e., ie i e (i.e. vs smallscale small scale biodiversity. . biodiversity) area s functioning macrofauna meiofauna listed information distribution 82 70 225 (22 spp., spp spp. , spp.) 194 (19 177 (17 spp.. 1 threatened exploited Furthermore threats i.e. (i.e 8 7 22 (2 19 (1 17 i.e 2 (
4.
Executive functions assessment in post-traumatic brain injury adults posttraumatic post traumatic
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Borges-Paraná, Camila Maia de Oliveira
; Zimmermann, Nicolle
; Cardoso, Caroline
; Fonseca, Rochele Paz
; Pereira, Ana Paula Almeida de
.
Resumo Objetivo A disfunção executiva após traumatismo cranioencefálico pode levar à diminuição da funcionalidade devido ao dano direto ao lobo frontal ou ao rompimento de suas conexões com outras partes do cérebro. Este estudo objetivou comparar o desempenho de adultos com e sem traumatismo cranioencefálico em tarefas de função executiva. Método O estudo apresenta delineamento transversal descritivo de análise quantitativa. Participaram 43 sujeitos divididos em grupo clínico (N =23, idade M = 34.3 [10.86]) e controle (N = 20, idade M = 38.3 [10.7]). A bateria foi composta por tarefas tradicionais de função executiva e a Tarefa Ecológica do Hotel. Resultados Encontrou-se diferença significativa na performance dos grupos nas medidas de planejamento (número de tarefas [t = -3.06; p < 0.01] e escore de planejamento [t = -3.06; p < 0.01]), reforçando a vantagem do uso de instrumentos tradicionais e ecológicos na avaliação neuropsicológica de funções executivas. Conclusão Os resultados sugerem que a tarefa ecológica pode discriminar melhor a disfunção executiva, reforçando a importância da utilização de atividades que simulem situações da vida real dos participantes. cérebro quantitativa 4 N 23 =23 343 34 3 34. 10.86 1086 10 86 [10.86] 20 383 38 38. 10.7. 107 10.7 . 7 [10.7]) Hotel Encontrouse Encontrou se número t 3.06 306 06 -3.06 0.01 001 0 01 0.01, , 0.01]) executivas participantes 2 =2 10.8 108 1 8 [10.86 10. [10.7] 3.0 30 -3.0 0.0 00 [10.8 [10.7 3. -3. 0. [10. -3 [10 - [1 [
Abstract Objective Executive dysfunction after traumatic brain injury may lead to reduced daily functionality due to direct damage to the frontal lobe or to disruption of its connections to other brain regions. This study aimed to compare the performance of adults with and without traumatic brain injury on executive functions tasks. Method The present study had a descriptive transversal design and included 43 participants divided into a clinical group (N = 23, age M = 34.3 [10.86]) and a control group (N = 20, age M = 38.3 [10.7]). The battery consisted of traditional instruments and the Ecological Hotel Task. Results A significant difference was found in the performance of the groups in the planning measures (number of tasks [t = -3.06; p < 0.01] and planning score [t = -3.06; p < 0.01]), highlighting the advantages of using both the traditional performance paradigms and the ecological tasks in neuropsychological assessment of executive functions. Conclusion Results suggested that the ecological task might discriminate better executive dysfunction, emphasizing the importance of using activities that simulate real-life situations of the participants. regions 4 N 23 343 34 3 34. 10.86 1086 10 86 [10.86] 20 383 38 38. 10.7. 107 10.7 . 7 [10.7]) Task number t 3.06 306 06 -3.06 0.01 001 0 01 0.01, , 0.01]) reallife real life 2 10.8 108 1 8 [10.86 10. [10.7] 3.0 30 -3.0 0.0 00 [10.8 [10.7 3. -3. 0. [10. -3 [10 - [1 [
5.
Impact of a forage legume or nitrogen fertilizer application on ammonia volatilization and nitrous oxide emissions in Brachiaria pastures
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Monteiro, Rafael Cassador
; Santos, Camila Almeida dos
; Rezende, Claudia de Paula
; Pereira, José Marques
; Macedo, Robert de Oliveira
; Alves, Bruno José Rodrigues
; Homem, Bruno Grossi C.
; Urquiaga, Segundo
; Zaman, Mohammad
; Boddey, Robert Michael
.
ABSTRACT The largest proportion of greenhouse gas (GHG) emissions in the Agriculture sector of the Brazilian national GHG inventory is derived from the large (>200 million head) herd of cattle. The greatest contribution to these emissions comes from the enteric methane from cattle, but the direct and indirect emissions of nitrous oxide (N2O) from cattle excreta and N fertilizer are responsible for approximately 9 % of all national anthropogenic GHG emissions. Ammonia (NH3) can be volatilized from N fertilizer and cattle excreta and deposited in sites remote from the source, constituting an indirect source of N2O. This study aimed to determine whether direct N2O emissions and NH3 volatilization from N-fertilized pastures were greater than those derived from a mixed grass-legume pasture without N fertilizer addition. Emissions of N2O and NH3 from excreta and N fertilizer from a Palisade grass (Urochloa brizantha cv. Marandu) monoculture fertilized with 2 × 60 kg N ha-1 yr-1 urea were compared to those from a mixed Palisade grass-forage peanut (Arachis pintoi) pasture. Dung and urine were collected from these cattle, and NH3 losses and N2O emissions from the excreta and from N fertilizer were monitored using static chamber techniques. Volatilization of NH3 and N2O emissions were found to be greater from urine than from dung. Ammonia losses from excreta and urea fertilizer were low, not exceeding 6.8, 1.1, and 4.7 % of the N applied as urine, dung, and fertilizer, respectively. The N2O emissions showed a tendency to be greater for the urine from the N-fertilized compared to the mixed grass-legume pasture, and the N2O emissions from the urine of the N-fertilized pasture ranged from 0.08 to 0.94 % of applied urine N. The N2O emission from the N fertilizer was at maximum 0.46 % of the applied N. The direct N2O emissions and the loss of NH3 by volatilization (indirect N2O emission) from the excreta of cattle grazing the mixed grass-legume pasture were similar to, or lower than, the grazed grass monoculture fertilized with 120 kg N ha-1 yr-1. As the mixed pasture received no N fertilizer and hence no GHG emission from its manufacture or application, introducing forage peanut to the Urochloa brizantha pastures shows potential to be responsible for lower GHG emissions than the N fertilized grass pasture. (GHG >200 200 (>20 head NO O (N2O NH (NH3 Nfertilized grasslegume legume addition cv Marandu 6 ha1 ha 1 ha- yr1 yr yr- grassforage Arachis pintoi techniques dung low 68 8 6.8 11 1.1 47 4 7 4. respectively 008 0 08 0.0 094 94 0.9 046 46 0.4 12 yr1. 1. application >20 20 (>2 (NH 6. 00 0. 09 04 >2 (> > (
6.
COVID-19 IN INFLAMMATORY BOWEL DISEASE: SHOULD WE BE MORE CAREFUL WITH THE USE OF SALICYLATES? COVID19 COVID 19 COVID-1 DISEASE SALICYLATES COVID1 1 COVID-
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MACEDO, Mariana Rolim Fernandes
; SOBREIRA, Carlos Arthur Fernandes
; LAVOR, Carola Braz de
; RÔLA, Camila Ribeiro
; ROLIM, Ticiana Maria de Lavor
; PESSOA, Francisco Sérgio Rangel de Paula
; GIRÃO, Milena Santana
; FREIRE, Caio César Furtado
; SIEBRA, Ranna Caroline Bezerra
; MELO, Isabele de Sá Silveira
; SOUZA, Marcellus Henrique Loiola Ponte de
; BRAGA, Lucia Libanez Bessa Campelo
; MELLO, Liana Perdigão
; SILVA, Débora Bezerra
; FARIAS, Luís Arthur Brasil Gadelha
; OLIVEIRA, Maura Salaroli de
; PERDIGÃO NETO, Lauro Vieira
; LEVIN, Anna Sara
.
RESUMO Contexto: Felizmente, muito se tem estudado sobre a COVID-19 em pacientes com doenças inflamatórias intestinais (DII). As evidências sugerem que esses pacientes não parecem ter risco aumentado de COVID-19 grave. Mas ainda se tem algumas incertezas com relação às manifestações clínicas da COVID-19 em portadores de doenças imunomediadas. Objetivo: Este estudo teve como objetivo descrever os principais sintomas da COVID-19 e sua frequência em pacientes com DII e avaliar o impacto dos medicamentos utilizados no tratamento das DII na apresentação clínica da COVID-19. Métodos: Pacientes adultos com DII de três hospitais públicos terciários de ensino do Ceará, Nordeste do Brasil, foram avaliados em consulta ambulatorial no período de março a dezembro de 2020. Pacientes com COVID-19 possível ou confirmada foram comparados com pacientes sem COVID-19. Além disso, as incidências de cada sintoma foram avaliadas com base no uso de medicamentos utilizados para tratamento da DII. Resultados: Foram incluídos no estudo 515 pacientes com DII: 234 com DC e 281 com RCU. Destes, 174 pacientes (34%) tinham COVID-19 possível/confirmado, dos quais 156 (90%) eram sintomáticos. Os principais sintomas foram febre (65%) e dor de cabeça (65%); sintomas gastrointestinais ocorreram em um terço dos pacientes, sendo mais frequentes do que na população geral com COVID-19. Os fatores associados a ter COVID-19 foram sexo feminino (OR 1,71, IC95%: 1,17-2,50); ter contato com caso de COVID-19, tanto intradomiciliar (OR 5,07; IC95%: 3,31-7,78) como fora do domicílio (OR 3,14; IC95%: 2,10-4,71); trabalhar fora de casa (OR 1,87; IC95%: 1,26-2,78); história familiar de COVID-19 (OR 2,29, IC95% 1,58-3,33), uso de salicilato (OR 1,71, IC95%: 1,17-4,28) e asma (OR 7,10; IC95%: 1,46-34,57). Conclusão: Pacientes com DII com alto risco de infecção por COVID-19 podem precisar evitar a terapia com salicilatos, mas mais estudos são necessários para confirmar esta associação. Contexto Felizmente COVID19 COVID 19 COVID-1 . (DII) grave imunomediadas Objetivo COVID19. 19. Métodos Ceará Brasil 2020 disso Resultados 51 23 28 RCU Destes 17 34% 34 (34% possívelconfirmado confirmado possível/confirmado 15 90% 90 (90% sintomáticos 65% 65 (65% OR 171 1 71 1,71 IC95 IC 1,172,50 117250 1,17 2,50 2 50 1,17-2,50) COVID19, 19, 5,07 507 5 07 3,317,78 331778 3,31 7,78 3 31 7 78 3,31-7,78 3,14 314 14 2,104,71 210471 2,10 4,71 10 4 2,10-4,71) 1,87 187 87 1,262,78 126278 1,26 2,78 26 1,26-2,78) 229 29 2,29 1,583,33, 158333 1,58 3,33 , 58 33 1,58-3,33) 1,174,28 117428 4,28 1,17-4,28 7,10 710 1,4634,57. 1463457 1,46 34,57 46 57 1,46-34,57) Conclusão salicilatos associação COVID1 COVID- (DII 202 (34 9 (90 6 (65 1,7 IC9 172 1,172,5 11725 117 1,1 250 2,5 1,17-2,50 5,0 0 317 3,317,7 33177 331 3,3 778 7,7 3,31-7,7 3,1 104 2,104,7 21047 210 2,1 471 4,7 2,10-4,71 1,8 18 8 262 1,262,7 12627 126 1,2 278 2,7 1,26-2,78 22 2,2 583 1,583,33 15833 158 1,5 333 1,58-3,33 1,174,2 11742 428 4,2 1,17-4,2 7,1 4634 1,4634,57 146345 146 1,4 3457 34,5 1,46-34,57 20 (3 (9 (6 1, 1,172, 1172 11 25 2, 1,17-2,5 5, 3,317, 3317 3, 77 7, 3,31-7, 2,104, 2104 21 47 4, 2,10-4,7 1,262, 1262 12 27 1,26-2,7 1,583,3 1583 1,58-3,3 1,174, 1174 42 1,17-4, 463 1,4634,5 14634 345 34, 1,46-34,5 ( 1,172 1,17-2, 3,317 3,31-7 2,104 2,10-4, 1,262 1,26-2, 1,583, 1,58-3, 1,174 1,17-4 1,4634, 1463 1,46-34, 1,17-2 3,31- 2,10-4 1,26-2 1,583 1,58-3 1,17- 1,4634 1,46-34 2,10- 1,26- 1,58- 1,463 1,46-3 1,46-
ABSTRACT Backgrounds: Fortunately, much has been studied about COVID-19 in patients with inflammatory bowel diseases (IBD). Evidence suggests that these patients do not appear to be at increased risk of severe COVID-19. However, there are still some uncertainties regarding the clinical manifestations of COVID-19 in patients with immune-mediated diseases. Objective: This study aimed to describe the main symptoms of COVID-19 and their frequency in IBD patients and evaluate the impact of the IBD therapeutic drugs on clinical presentation of COVID-19 and to determine factors associated with COVID-19 in this population. Methods: Adult patients with IBD from three tertiary-care public, teaching hospitals in Ceará, Northeastern Brazil, were evaluated during one scheduled appointment from March to December 2020. Patients with possible or confirmed COVID-19 were compared with patients without COVID-19. Furthermore, incidences of each symptom were evaluated based on the use of IBD therapeutic drugs. Results: A total of 515 patients with IBD were included in the study: 234 with CD, and 281 with UC. Of these, 174 patients (34%) had possible/confirmed COVID-19 of whom 156 (90%) were symptomatic. Main symptoms were fever (65%) and headache (65%); gastrointestinal symptoms occurred in one third of patients and were higher than COVID-19 in general population. The factors associated with having COVID-19 were female gender (OR 1.71, 95%CI: 1.17-2.50); contact at home (OR 5.07, 95%CI: 3.31-7.78) and outside the home (OR 3.14, 95%CI: 2.10-4.71) with a case of COVID-19; work outside of the home (OR 1.87, 95%CI: 1.26-2.78); family history of COVID-19 (OR 2.29, 95%CI 1.58-3.33) use of salicylate (OR 1.71, 95%CI: 1.17-4.28); and asthma (OR 7.10, 95%CI: 1.46-34.57). Conclusion: IBD patients at high risk of COVID-19 infection may need to avoid salicylate therapy but further studies are necessary to confirm this association. Backgrounds Fortunately COVID19 COVID 19 COVID-1 IBD. . (IBD) COVID19. 19. However immunemediated immune mediated Objective population Methods tertiarycare tertiary care public Ceará Brazil 2020 Furthermore Results 51 23 CD 28 UC 17 34% 34 (34% possibleconfirmed 15 90% 90 (90% symptomatic 65% 65 (65% OR 171 1 71 1.71 95CI CI 95 1.172.50 117250 1.17 2.50 2 50 1.17-2.50) 507 5 07 5.07 3.317.78 331778 3.31 7.78 3 31 7 78 3.31-7.78 314 14 3.14 2.104.71 210471 2.10 4.71 10 4 2.10-4.71 187 87 1.87 1.262.78 126278 1.26 2.78 26 1.26-2.78) 229 29 2.29 1.583.33 158333 1.58 3.33 58 33 1.58-3.33 1.174.28 117428 4.28 1.17-4.28) 710 7.10 1.4634.57. 1463457 1.46 34.57 46 57 1.46-34.57) Conclusion association COVID1 COVID- (IBD 202 (34 9 (90 6 (65 1.7 172 1.172.5 11725 117 1.1 250 2.5 1.17-2.50 0 5.0 317 3.317.7 33177 331 3.3 778 7.7 3.31-7.7 3.1 104 2.104.7 21047 210 2.1 471 4.7 2.10-4.7 18 8 1.8 262 1.262.7 12627 126 1.2 278 2.7 1.26-2.78 22 2.2 583 1.583.3 15833 158 1.5 333 1.58-3.3 1.174.2 11742 428 4.2 1.17-4.28 7.1 4634 1.4634.57 146345 146 1.4 3457 34.5 1.46-34.57 20 (3 (9 (6 1. 1.172. 1172 11 25 2. 1.17-2.5 5. 3.317. 3317 3. 77 7. 3.31-7. 2.104. 2104 21 47 4. 2.10-4. 1.262. 1262 12 27 1.26-2.7 1.583. 1583 1.58-3. 1.174. 1174 42 1.17-4.2 463 1.4634.5 14634 345 34. 1.46-34.5 ( 1.172 1.17-2. 3.317 3.31-7 2.104 2.10-4 1.262 1.26-2. 1.583 1.58-3 1.174 1.17-4. 1.4634. 1463 1.46-34. 1.17-2 3.31- 2.10- 1.26-2 1.58- 1.17-4 1.4634 1.46-34 1.17- 1.26- 1.463 1.46-3 1.46-
7.
Inhaled nitric oxide in moderate-to-severe COVID-19 acute respiratory distress syndrome: a retrospective cohort study moderatetosevere moderate to severe COVID19 COVID 19 COVID-1 syndrome COVID1 1 COVID-
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Santos, Lucas Eduardo Benthien
; Padovese, Camila Campos Grisa
; Castro, Isabela Belarmino Oliveira de
; Franco, Rodrigo Carneiro
; Okuda, Ana Paula Pires Bolsoni
; Bustamante, Mariana Resende
; Gioli-Pereira, Luciana
.
ABSTRACT Objective To evaluate the responsiveness of COVID-19 acute respiratory distress syndrome patients to inhaled nitric oxide as part of their standard therapy. Methods This retrospective cohort study included critically ill adult patients with confirmed COVID-19 treated between March 2020 and May 2021. Eligible patients with moderate-to-severe acute respiratory distress syndrome due to COVID-19 were subsequently categorized into two groups based on inhaled nitric oxide use throughout their stay in the intensive care unit. The primary endpoints were overall mortality and improvement in oxygenation parameters 6 hours after inhaled nitric oxide use. Results A total of 481 patients admitted to the intensive care unit due to COVID-19 acute respiratory distress syndrome were screened, 105 of which were included. Among the 105 patients, inhaled nitric oxide therapy was used in 33 patients, will 72 did not undergo inhaled nitric oxide therapy. No significant difference in mortality was observed between the groups (67% for the treatment and 82% for the no-treatment groups respectively, p=0.173). Among the patients who used inhaled nitric oxide, 17 (51%) were considered responsive to therapy. There was no significant difference in the length of stay in the intensive care unit (p=0.324) or total hospitalization time (p=0.344). Conclusion Inhaled nitric oxide rescue therapy improved oxygenation in patients with COVID-19 with moderate-to-severe acute respiratory distress syndrome but did not affect mortality. COVID19 COVID 19 COVID-1 202 2021 moderatetosevere moderate severe 48 screened 10 3 7 67% 67 (67 82 notreatment respectively p=0.173. p0173 p p=0.173 . 0 173 p=0.173) 1 51% 51 (51% p=0.324 p0324 324 (p=0.324 p=0.344. p0344 p=0.344 344 (p=0.344) COVID1 COVID- 20 4 (6 8 p017 p=0.17 5 (51 p=0.32 p032 32 (p=0.32 p034 p=0.34 34 (p=0.344 2 ( p01 p=0.1 (5 p=0.3 p03 (p=0.3 (p=0.34 p0 p=0. (p=0. p=0 (p=0 p= (p= (p
8.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
9.
Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer ChAdOx SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- arthritis SARS-CoV
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Cruz, Vitor Alves
; Guimarães, Camila
; Rêgo, Jozelia
; Machado, Ketty Lysie Libardi Lira
; Miyamoto, Samira Tatiyama
; Burian, Ana Paula Neves
; Dias, Laiza Hombre
; Pretti, Flavia Zon
; Batista, Danielle Cristina Filgueira Alves
; Mill, José Geraldo
; Oliveira, Yasmin Gurtler Pinheiro de
; Gadelha, Carolina Strauss Estevez
; Gouveia, Maria da Penha Gomes
; Moulin, Anna Carolina Simões
; Souza, Bárbara Oliveira
; Aguiar, Laura Gonçalves Rodrigues
; Vieira, Gabriel Smith Sobral
; Grillo, Luiza Lorenzoni
; Lima, Marina Deorce de
; Pasti, Laís Pizzol
; Surlo, Heitor Filipe
; Faé, Filipe
; Moulaz, Isac Ribeiro
; Macabú, Mariana de Oliveira
; Ribeiro, Priscila Dias Cardoso
; Magalhães, Vanessa de Oliveira
; Aguiar, Mariana Freitas de
; Biegelmeyer, Erika
; Peixoto;, Flávia Maria Matos Melo Campos
; Kayser, Cristiane
; Souza, Alexandre Wagner Silva de
; Castro, Charlles Heldan de Moura
; Ribeiro, Sandra Lúcia Euzébio
; Telles, Camila Maria Paiva França
; Bühring, Juliana
; Lima, Raquel Lima de
; Santos, Sérgio Henrique Oliveira Dos
; Dias, Samuel Elias Basualto
; Melo, Natália Seixas de
; Sanches, Rosely Holanda da Silva
; Boechat, Antonio Luiz
; Sartori, Natália Sarzi
; Hax, Vanessa
; Dória, Lucas Denardi
; Rezende, Rodrigo Poubel Vieira de
; Baptista, Katia Lino
; Fortes, Natália Rodrigues Querido
; Melo, Ana Karla Guedes de
; Melo, Tâmara Santos
; Vieira, Rejane Maria Rodrigues de Abreu
; Vieira, Adah Sophia Rodrigues
; Kakehasi, Adriana Maria
; Tavares, Anna Carolina Faria Moreira Gomes
; Landa, Aline Teixeira de
; Costa, Pollyana Vitoria Thomaz da
; Azevedo, Valderilio Feijó
; Martins-Filho, Olindo Assis
; Peruhype-Magalhães, Vanessa
; Pinheiro, Marcelo de Medeiros
; Monticielo, Odirlei André
; Reis-neto, Edgard Torres Dos
; Ferreira, Gilda Aparecida
; Souza, Viviane Angelina de
; Teixeira-Carvalho, Andréa
; Xavier, Ricardo Machado
; Sato, Emilia Inoue
; Valim, Valeria
; Pileggi, Gecilmara Salviato
; Silva, Nilzio Antonio da
.
Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26
10.
Delineamento e Racional do Estudo Rosa dos Ventos: Estudo Multicêntrico do Tipo Coorte de Pacientes com Insuficiência Cardíaca com Fração de Ejeção Reduzida ou Moderadamente Reduzida no Brasil Ventos
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Freitas, Dhayn Cassi de Almeida
; da Costa, Larissa Maria de Paula Rebouças
; Nadruz Jr., Wilson
; Marcondes-Braga, Fabiana G.
; Vieira, Jefferson Luis
; Bernardez-Pereira, Sabrina
; Barbosa Neto, Wilson Rodrigues
; Alves, Silvia Marinho Martins
; Wanderley, Gabriela Arcoverde
; Lira, Camila Nogueira Leandro
; Terui, Lucas Yugi de Souza
; Silva, Ana Luísa Guedes de França e
; Castro, Alana de Oliveira
; Freitas Jr., Aguinaldo F.
; de Figueiredo Neto, José Albuquerque
; Lopes, Renato D.
; Fernandes-Silva, Miguel Morita
; Silvestre, Odilson Marcos
.
Arquivos Brasileiros de Cardiologia
- Métricas do periódico
Resumo Fundamento: O Brasil é um país com diferentes biomas e desigualdades sociais. Existem poucos dados disponíveis sobre as diferenças regionais e o prognóstico da insuficiência cardíaca (IC) no país. Objetivo: O estudo Rosa dos Ventos tem como objetivo investigar as diferenças regionais e o prognóstico atual de pacientes com IC com fração de ejeção reduzida ou moderadamente reduzida no Brasil. Métodos: Este é um estudo prospectivo, multicêntrico, observacional, do tipo coorte que incluirá pacientes ambulatoriais com idade superior a 18 anos com IC e fração de ejeção < 50% em 30 centros privados distribuídos nas regiões brasileiras. Um total de 2500 pacientes serão incluídos entre junho de 2021 e outubro de 2023, com um período de 12 meses de seguimento. Coletaremos dados sobre status clínico e socioeconômico, prescrição médica e resultados de exames cardiológicos. Serão realizados telefonemas para o seguimento dos pacientes seis e 12 meses após a inclusão para coleta de informações sobre visitas ao departamento de emergência, internações e mortalidade. Conclusão: O estudo Rosa dos Ventos permitirá uma caracterização mais precisa da IC crônica no Brasil. Essa iniciativa proverá informações relevantes para o desenvolvimento de estratégias de manejo efetivas para mitigar o impacto dessa condição sobre os pacientes e o sistema de saúde. Fundamento sociais (IC Objetivo Métodos prospectivo multicêntrico observacional 1 50 3 brasileiras 250 202 2023 socioeconômico cardiológicos emergência mortalidade Conclusão saúde 5 25 20 2
Abstract Background: Brazil is a country with different biomes and social disparities. There are limited data available on regional differences and prognosis of heart failure (HF) in the country. Objective: The Rosa dos Ventos study aims to investigate regional differences and the current prognosis of HF outpatients with reduced or mildly reduced ejection fraction in Brazil. Methods: This is a prospective, multicenter, observational cohort study that will include outpatients older than 18 years with HF and an ejection fraction < 50% in 30 public and private centers distributed in all Brazilian regions. A total of 2,500 patients will be enrolled from June 2021 and October 2023, with a 12-month follow-up period. We will collect data on socioeconomic and clinical status, medical prescription and results of cardiology tests. Follow-up phone calls will be made at 6 and 12 months after inclusion to collect information regarding emergency room visits, hospitalization and mortality. Conclusion: The Rosa dos Ventos study will allow a more accurate characterization of chronic HF in Brazil. This initiative will provide relevant information for the development of effective management strategies to mitigate the impact of this condition on patients and the healthcare system. Background disparities (HF Objective Methods prospective multicenter 1 50 3 regions 2500 2 500 2,50 202 2023 12month month followup follow up period status tests Followup Follow visits mortality Conclusion system 5 250 2,5 20 25 2,
11.
Brazilian consensus for diagnosis, management and treatment of hereditary transthyretin amyloidosis with peripheral neuropathy: second edition diagnosis neuropathy
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Pinto, Marcus Vinicius
; França Jr, Marcondes Cavalcante
; Gonçalves, Marcus Vinicius Magno
; Machado-Costa, Marcela Câmara
; Freitas, Marcos Raimundo Gomes de
; Gondim, Francisco de Assis Aquino
; Marrone, Carlo Domenico
; Martinez, Alberto Rolim Muro
; Moreira, Carolina Lavigne
; Nascimento, Osvaldo J. M.
; Covaleski, Anna Paula Paranhos
; Oliveira, Acary Souza Bulle de
; Pupe, Camila Castelo Branco
; Rodrigues, Marcia Maria Jardim
; Rotta, Francisco Tellechea
; Scola, Rosana Herminia
; Marques Jr, Wilson
; Waddington-Cruz, Márcia
.
Resumo Polineuropatia amiloidótica familiar associada a transtirretina (ATTRv-PN) é uma polineuropatia sensitivo-motora e autonômica hereditária autossômica dominante com mais de 130 variantes patogênicas já identificadas no gene TTR. A ATTRv-PN é uma condição genética debilitante, progressiva e que ameaça a vida, levando à morte em ~ 10 anos se não for tratada. Nas últimas décadas, a ATTRv-PN se tornou uma neuropatia tratável. Além do transplante de fígado, iniciado em 1990, temos agora 3 medicamentos modificadores de doença aprovados em muitos países, incluindo o Brasil, e muitas outras medicações estão em desenvolvimento. O primeiro consenso brasileiro em ATTRv-PN foi realizado em Fortaleza em junho de 2017. Devido aos novos avanços nesta área nos últimos 5 anos, o Departamento Científico de Neuropatias Periféricas da Academia Brasileira de Neurologia organizou uma segunda edição do consenso. Cada panelista ficou responsável por rever a literatura e atualizar uma parte do manuscrito. Finalmente, os 18 panelistas se reuniram virtualmente após revisão da primeira versão, discutiram cada parte do artigo e chegaram a um consenso sobre a versão final do manuscrito. ATTRvPN ATTRv PN (ATTRv-PN sensitivomotora sensitivo motora 13 TTR debilitante vida 1 tratada décadas tratável fígado 1990 países Brasil desenvolvimento 2017 manuscrito Finalmente 199 201 19 20 2
Abstract Hereditary transthyretin amyloidosis with peripheral neuropathy (ATTRv-PN) is an autosomal dominant inherited sensorimotor and autonomic polyneuropathy with over 130 pathogenic variants identified in the TTR gene. Hereditary transthyretin amyloidosis with peripheral neuropathy is a disabling, progressive and life-threatening genetic condition that leads to death in ~ 10 years if untreated. The prospects for ATTRv-PN have changed in the last decades, as it has become a treatable neuropathy. In addition to liver transplantation, initiated in 1990, there are now at least 3 drugs approved in many countries, including Brazil, and many more are being developed. The first Brazilian consensus on ATTRv-PN was held in the city of Fortaleza, Brazil, in June 2017. Given the new advances in the area over the last 5 years, the Peripheral Neuropathy Scientific Department of the Brazilian Academy of Neurology organized a second edition of the consensus. Each panelist was responsible for reviewing the literature and updating a section of the previous paper. Thereafter, the 18 panelists got together virtually after careful review of the draft, discussed each section of the text, and reached a consensus for the final version of the manuscript. ATTRvPN ATTRv PN (ATTRv-PN 13 gene disabling lifethreatening life threatening 1 untreated decades transplantation 1990 countries Brazil developed Fortaleza 2017 paper Thereafter draft text manuscript 199 201 19 20 2
12.
Working conditions in nursing in the face of Covid-19 from the perspective of precariousness Covid19 Covid 19 Covid-1 Covid1 1 Covid-
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Magalhães, Ana Paula Nogueira de
; Souza, Diego de Oliveira
; Macêdo, Fernanda Pereira de
; Silva Cruz, Sabrina Ângela França da
; Pereira-Abagaro, Camila
; Rosales-Flores, Roselia Arminda
.
RESUMEN Objetivo: Investigar las condiciones de trabajo de la enfermería para el afrontamiento del Covid-19, según la visión de la precarización del trabajo. Métodos: Es un estudio transversal realizado entre 131 trabajadoras(es) de enfermería que actuaron contra el Covid-19 en hospitales de Alagoas, Brasil. Los datos se recogieron online mediante un cuestionario de la salud de los trabajadores, con la Prueba X2 o Exacto de Fisher y regresión logística. Resultados: El 71% tenía contratos precarios, 33,6% declaró jornadas laborales prolongadas y 23,7% estaba sindicado. En el análisis multivariado, tener poca experiencia hospitalaria fue un factor predictivo del empleo precario (OR= 2,408; IC95%= 1,051-5,518). Las variables predictoras de jornadas laborales extendidas fueron: ser enfermera(o) (OR= 3,824; IC95%=1,274-11,483); horas extraordinarias (OR= 3,668; IC95%= 1,009-13,333) y número inadecuado de trabajadores (OR= 10,872; IC95% =3,409-34,675). Ser técnica(o) de enfermería fue un factor predictivo de estar sindicado (OR= 8,967; IC 95%= 2,560-31,410). Conclusiones: La pandemia acentuó la precarización de las condiciones de trabajo en la enfermería, principalmente entre las(os) enfermeras(os). Objetivo Covid19, Covid19 Covid 19, 19 Métodos 13 trabajadorases trabajadoras es trabajadoras(es Covid-1 Alagoas Brasil X logística Resultados 71 precarios 336 33 6 33,6 237 23 7 23,7 multivariado OR= OR (OR 2,408 2408 2 408 IC95 1,0515,518. 10515518 1,051 5,518 . 1 051 5 518 1,051-5,518) fueron enfermerao enfermera enfermera(o 3,824 3824 3 824 IC95%=1,27411,483 IC95127411483 IC95%=1,274 11,483 274 11 483 IC95%=1,274-11,483) 3,668 3668 668 1,00913,333 100913333 1,009 13,333 009 333 1,009-13,333 10,872 10872 10 872 =3,40934,675. 340934675 =3,409 34,675 409 34 675 =3,409-34,675) técnicao técnica técnica(o 8,967 8967 8 967 95 95% 2,56031,410. 256031410 2,560 31,410 560 31 410 2,560-31,410) Conclusiones lasos os las(os enfermerasos. enfermerasos enfermeras enfermeras(os) Covid1 Covid- 33, 23, 2,40 240 40 IC9 0515 1,0515,518 1051551 1051 1,05 5518 5,51 05 51 1,051-5,518 3,82 382 82 27411 IC95%=1,27411,48 IC9512741148 IC951274 IC95%=1,27 11483 11,48 27 48 IC95%=1,274-11,483 3,66 366 66 00913 1,00913,33 10091333 1009 1,00 13333 13,33 00 1,009-13,33 10,87 1087 87 40934 =3,40934,675 34093467 3409 =3,40 34675 34,67 67 =3,409-34,675 8,96 896 96 9 56031 2,56031,410 25603141 2560 2,56 31410 31,41 56 41 2,560-31,410 enfermeras(os 2,4 24 4 1,0515,51 105155 105 1,0 551 5,5 0 1,051-5,51 3,8 38 2741 IC95%=1,27411,4 IC951274114 IC95127 IC95%=1,2 1148 11,4 IC95%=1,274-11,48 3,6 36 0091 1,00913,3 1009133 100 1333 13,3 1,009-13,3 10,8 108 4093 =3,40934,67 3409346 340 =3,4 3467 34,6 =3,409-34,67 8,9 89 5603 2,56031,41 2560314 256 2,5 3141 31,4 2,560-31,41 2, 1,0515,5 10515 1, 55 5, 1,051-5,5 3, IC95%=1,27411, IC95127411 IC9512 IC95%=1, 114 11, IC95%=1,274-11,4 1,00913, 100913 133 13, 1,009-13, 10, =3,40934,6 340934 =3, 346 34, =3,409-34,6 8, 2,56031,4 256031 25 314 31, 2,560-31,4 1,0515, 1,051-5, IC95%=1,27411 IC9512741 IC951 IC95%=1 IC95%=1,274-11, 1,00913 10091 1,009-13 =3,40934, 34093 =3 =3,409-34, 2,56031, 25603 2,560-31, 1,0515 1,051-5 IC95%=1,2741 IC95%=1,274-11 1,0091 1,009-1 =3,40934 = =3,409-34 2,56031 2,560-31 1,051- IC95%=1,274-1 1,009- =3,4093 =3,409-3 2,5603 2,560-3 IC95%=1,274- =3,409- 2,560-
ABSTRACT Objective: To investigate working conditions in nursing when facing the Covid-19 pandemic, in light of aspects of precarious work. Methods: Cross-sectional study, with 131 nursing workers who worked against Covid-19 in hospitals in Alagoas State, Northeast Brazil. Data were collected online, using a workers’ health assessment questionnaire. The Chi -Square or Fisher’s Exact test and logistic regression were used. Results: among nursing workers, 71% had precarious contracts, 33.6% reported extended working hours and 23.7% were union members. In the multivariable analysis, having little hospital experience was a predictor for poor employment (OR= 2.408; 95%CI= 1.051-5.518). The predictor variables for lengthening the working day were being a nurse (OR= 3.824; 95%CI= 1.274-11.483); overtime (OR= 3.668; 95%CI= 1.009-13.333) and inadequate number of workers (OR= 10.872; 95%CI= 3.409-34.675). Being a nursing technician was a predictor of being a union member (OR= 8.967; 95%CI=2.560-31.410). Conclusions: The pandemic has accentuated the precariousness of working conditions in nursing professionals, especially among nurses. Objective Covid19 Covid 19 Covid-1 work Methods Crosssectional Cross sectional study 13 State Brazil online questionnaire Square Fishers Fisher s used Results 71 contracts 336 33 6 33.6 237 23 7 23.7 members analysis OR= OR (OR 2.408 2408 2 408 95CI CI 95 95%CI 1.0515.518. 10515518 1.051 5.518 . 1 051 5 518 1.051-5.518) 3.824 3824 3 824 1.27411.483 127411483 1.274 11.483 274 11 483 1.274-11.483) 3.668 3668 668 1.00913.333 100913333 1.009 13.333 009 333 1.009-13.333 10.872 10872 10 872 3.40934.675. 340934675 3.409 34.675 409 34 675 3.409-34.675) 8.967 8967 8 967 95%CI=2.56031.410. 95CI256031410 95%CI=2.560 31.410 560 31 410 95%CI=2.560-31.410) Conclusions professionals nurses Covid1 Covid- 33. 23. 2.40 240 40 9 0515 1.0515.518 1051551 1051 1.05 5518 5.51 05 51 1.051-5.518 3.82 382 82 27411 1.27411.48 12741148 1274 1.27 11483 11.48 27 48 1.274-11.483 3.66 366 66 00913 1.00913.33 10091333 1009 1.00 13333 13.33 00 1.009-13.33 10.87 1087 87 40934 3.40934.675 34093467 3409 3.40 34675 34.67 67 3.409-34.675 8.96 896 96 56031 95%CI=2.56031.410 95CI25603141 95CI2560 95%CI=2.56 31410 31.41 56 41 95%CI=2.560-31.410 2.4 24 4 1.0515.51 105155 105 1.0 551 5.5 0 1.051-5.51 3.8 38 2741 1.27411.4 1274114 127 1.2 1148 11.4 1.274-11.48 3.6 36 0091 1.00913.3 1009133 100 1333 13.3 1.009-13.3 10.8 108 4093 3.40934.67 3409346 340 3.4 3467 34.6 3.409-34.67 8.9 89 5603 95%CI=2.56031.41 95CI2560314 95CI256 95%CI=2.5 3141 31.4 95%CI=2.560-31.41 2. 1.0515.5 10515 1. 55 5. 1.051-5.5 3. 1.27411. 127411 12 114 11. 1.274-11.4 1.00913. 100913 133 13. 1.009-13. 10. 3.40934.6 340934 346 34. 3.409-34.6 8. 95%CI=2.56031.4 95CI256031 95CI25 95%CI=2. 314 31. 95%CI=2.560-31.4 1.0515. 1.051-5. 1.27411 12741 1.274-11. 1.00913 10091 1.009-13 3.40934. 34093 3.409-34. 95%CI=2.56031. 95CI25603 95CI2 95%CI=2 95%CI=2.560-31. 1.0515 1.051-5 1.2741 1.274-11 1.0091 1.009-1 3.40934 3.409-34 95%CI=2.56031 95%CI=2.560-31 1.051- 1.274-1 1.009- 3.4093 3.409-3 95%CI=2.5603 95%CI=2.560-3 1.274- 3.409- 95%CI=2.560-
RESUMO Objetivo: Investigar as condições de trabalho em enfermagem no enfrentamento da pandemia de Covid-19, à luz de aspectos da precarização do trabalho. Métodos: Estudo transversal, com 131 trabalhadoras(es) da enfermagem que atuaram contra a Covid-19 em hospitais alagoanos, no Nordeste brasileiro. Os dados foram coletados online, por questionário de avaliação da saúde dos trabalhadores. Utilizaram-se o teste do Qui-Quadrado ou Exato de Fisher e a regressão logística. Resultados: Entre as(os) trabalhadoras(es), 71% tiveram contratos precários, 33,6% referiram ao prolongamento da jornada e 23,7% eram sindicalizadas(os). Na análise multivariável, ter pouca experiência hospitalar foi preditor para o vínculo precário (OR= 2,408; IC95%= 1,051-5,518). As variáveis preditoras para o prolongamento da jornada foram: ser enfermeira(o) (OR= 3,824; IC95%= 1,274-11,483), horas extras (OR= 3,668; IC95%=1,009-13,333) e número inadequado de trabalhadoras(es) (OR= 10,872; IC95%= 3,409-34,675). Ser técnica(o) de enfermagem foi preditor para ser sindicalizada(o) (OR= 8,967; IC95%=2,560-31,410). Conclusões: A pandemia acentuou a precarização das condições de trabalho em enfermagem, principalmente entre as(os) enfermeiras(os). Objetivo Covid19, Covid19 Covid 19, 19 Métodos transversal 13 trabalhadorases trabalhadoras es trabalhadoras(es Covid-1 alagoanos brasileiro online trabalhadores Utilizaramse Utilizaram se QuiQuadrado Qui Quadrado logística Resultados asos os as(os trabalhadorases, , 71 precários 336 33 6 33,6 237 23 7 23,7 sindicalizadasos. sindicalizadasos sindicalizadas . sindicalizadas(os) multivariável OR= OR (OR 2,408 2408 2 408 IC95 IC IC95% 1,0515,518. 10515518 1,051 5,518 1 051 5 518 1,051-5,518) enfermeirao enfermeira enfermeira(o 3,824 3824 3 824 1,27411,483, 127411483 1,274 11,483 274 11 483 1,274-11,483) 3,668 3668 668 IC95%=1,00913,333 IC95100913333 IC95%=1,009 13,333 009 333 IC95%=1,009-13,333 10,872 10872 10 872 3,40934,675. 340934675 3,409 34,675 409 34 675 3,409-34,675) técnicao técnica técnica(o sindicalizadao sindicalizada sindicalizada(o 8,967 8967 8 967 IC95%=2,56031,410. IC95256031410 IC95%=2,560 31,410 560 31 410 IC95%=2,560-31,410) Conclusões enfermeirasos. enfermeirasos enfermeiras enfermeiras(os) Covid1 Covid- 33, 23, sindicalizadas(os 2,40 240 40 IC9 0515 1,0515,518 1051551 1051 1,05 5518 5,51 05 51 1,051-5,518 3,82 382 82 27411 1,27411,483 12741148 1274 1,27 11483 11,48 27 48 1,274-11,483 3,66 366 66 00913 IC95%=1,00913,33 IC9510091333 IC951009 IC95%=1,00 13333 13,33 00 IC95%=1,009-13,33 10,87 1087 87 40934 3,40934,675 34093467 3409 3,40 34675 34,67 67 3,409-34,675 8,96 896 96 56031 IC95%=2,56031,410 IC9525603141 IC952560 IC95%=2,56 31410 31,41 56 41 IC95%=2,560-31,410 enfermeiras(os 2,4 24 4 1,0515,51 105155 105 1,0 551 5,5 0 1,051-5,51 3,8 38 2741 1,27411,48 1274114 127 1,2 1148 11,4 1,274-11,48 3,6 36 0091 IC95%=1,00913,3 IC951009133 IC95100 IC95%=1,0 1333 13,3 IC95%=1,009-13,3 10,8 108 4093 3,40934,67 3409346 340 3,4 3467 34,6 3,409-34,67 8,9 89 9 5603 IC95%=2,56031,41 IC952560314 IC95256 IC95%=2,5 3141 31,4 IC95%=2,560-31,41 2, 1,0515,5 10515 1, 55 5, 1,051-5,5 3, 1,27411,4 127411 12 114 11, 1,274-11,4 IC95%=1,00913, IC95100913 IC9510 IC95%=1, 133 13, IC95%=1,009-13, 10, 3,40934,6 340934 346 34, 3,409-34,6 8, IC95%=2,56031,4 IC95256031 IC9525 IC95%=2, 314 31, IC95%=2,560-31,4 1,0515, 1,051-5, 1,27411, 12741 1,274-11, IC95%=1,00913 IC9510091 IC951 IC95%=1 IC95%=1,009-13 3,40934, 34093 3,409-34, IC95%=2,56031, IC9525603 IC952 IC95%=2 IC95%=2,560-31, 1,0515 1,051-5 1,27411 1,274-11 IC95%=1,0091 IC95%=1,009-1 3,40934 3,409-34 IC95%=2,56031 IC95%=2,560-31 1,051- 1,2741 1,274-1 IC95%=1,009- 3,4093 3,409-3 IC95%=2,5603 IC95%=2,560-3 1,274- 3,409- IC95%=2,560-
13.
Relationship of residual feed intake with semen parameters and testicular ultrasound of Nellore bulls
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Borges, Marcelo Sant’Ana
; Silva, Marina de Oliveira
; Fernandes, Luana Gomes
; Rodrigues, Naiara Nantes
; Rossi, Guilherme Fazan
; Freitas-Dell’Aqua, Camila de Paula
; Bonilha, Sarah Figueiredo Martins
; Mercadante, Maria Eugênia Zerlotti
; Monteiro, Fabio Morato
.
ABSTRACT The objective of this study was to evaluate characteristics of the testicular parenchyma and vascular parameters of the pampiniform plexus obtained by ultrasound, semen quality parameters, and sperm freezability in Nellore bulls classified based on residual feed intake (RFI). Twenty-seven bulls (21.82±0.88 months of age) evaluated for feed efficiency were sampled for the study, including 15 with low RFI (−0.592±0.09 kg dry matter/day) and 12 with high RFI (0.792±0.10 kg dry matter/day). In ultrasound and Doppler assessment, the most efficient animals (low RFI) showed higher pulsatility and resistive indexes, as well as a tendency towards greater heterogeneity of the testicular parenchyma (0.625±0.032 vs. 0.508±0.032, 1.012±0.072 vs. 0.802±0.072, and 12.9±0.96 vs. 10.2±0.96, respectively, for low vs. high RFI). However, these animals tended to have lower peak diastolic velocity (5.19±0.50 for low RFI vs. 6.54±0.50 for high RFI). Analysis of fresh semen showed a lower percentage of minor defects in low RFI animals (2.67±1.19%) compared with high RFI animals (8.10±1.19%), without differences in the other parameters in fresh or thawed semen and after thermoresistance testing. Evaluation of flow cytometry parameters showed a higher quality of mitochondrial respiration in semen samples of low RFI animals (22.04±2.50%) compared with high RFI animals (12.29±2.71%). Therefore, although RFI exerts an effect on the Doppler parameters of the pampiniform plexus, it is not sufficient to affect the quality of fresh or thawed semen. RFI. . (RFI) Twentyseven Twenty seven 21.82±0.88 2182088 21 82 0 88 (21.82±0.8 age 1 −0.592±0.09 0592009 592 09 (−0.592±0.0 matter/day matterday matter day 0.792±0.10 0792010 792 10 (0.792±0.1 matter/day. assessment indexes 0.625±0.032 06250032 625 032 (0.625±0.03 vs 05080032 508 0.508±0.032 10120072 012 072 1.012±0.07 08020072 802 0.802±0.072 129096 9 96 12.9±0.9 102096 2 10.2±0.96 respectively However 5.19±0.50 519050 5 19 50 (5.19±0.5 654050 6 54 6.54±0.5 2.67±1.19% 267119 67 (2.67±1.19% 8.10±1.19%, 810119 8.10±1.19% , 8 (8.10±1.19%) testing 22.04±2.50% 2204250 22 04 (22.04±2.50% 12.29±2.71%. 1229271 12.29±2.71% 29 71 (12.29±2.71%) Therefore (RFI 21.82±0.8 218208 (21.82±0. −0.592±0.0 059200 59 (−0.592±0. 0.792±0.1 079201 79 (0.792±0. 0.625±0.03 0625003 62 03 (0.625±0.0 0508003 0.508±0.03 1012007 01 07 1.012±0.0 0802007 80 0.802±0.07 12909 12.9±0. 10209 10.2±0.9 5.19±0.5 51905 (5.19±0. 65405 6.54±0. 2.67±1.19 26711 (2.67±1.19 81011 8.10±1.19 (8.10±1.19% 22.04±2.50 220425 (22.04±2.50 122927 12.29±2.71 7 (12.29±2.71% 21.82±0. 21820 (21.82±0 −0.592±0. 05920 (−0.592±0 0.792±0. 07920 (0.792±0 0.625±0.0 062500 (0.625±0. 050800 0.508±0.0 101200 1.012±0. 080200 0.802±0.0 1290 12.9±0 1020 10.2±0. 5.19±0. 5190 (5.19±0 6540 6.54±0 2.67±1.1 2671 (2.67±1.1 8101 8.10±1.1 (8.10±1.19 22.04±2.5 22042 (22.04±2.5 12292 12.29±2.7 (12.29±2.71 21.82±0 2182 (21.82± −0.592±0 0592 (−0.592± 0.792±0 0792 (0.792± 0.625±0. 06250 (0.625±0 05080 0.508±0. 10120 1.012±0 08020 0.802±0. 129 12.9± 102 10.2±0 5.19±0 519 (5.19± 654 6.54± 2.67±1. 267 (2.67±1. 810 8.10±1. (8.10±1.1 22.04±2. 2204 (22.04±2. 1229 12.29±2. (12.29±2.7 21.82± 218 (21.82 −0.592± 059 (−0.592 0.792± 079 (0.792 0.625±0 0625 (0.625± 0508 0.508±0 1012 1.012± 0802 0.802±0 12.9 10.2± 5.19± 51 (5.19 65 6.54 2.67±1 26 (2.67±1 81 8.10±1 (8.10±1. 22.04±2 220 (22.04±2 122 12.29±2 (12.29±2. 21.82 (21.8 −0.592 05 (−0.59 0.792 (0.79 0.625± 062 (0.625 050 0.508± 101 1.012 080 0.802± 12. 10.2 5.19 (5.1 6.5 2.67± (2.67± 8.10± (8.10±1 22.04± (22.04± 12.29± (12.29±2 21.8 (21. −0.59 (−0.5 0.79 (0.7 0.625 06 (0.62 0.508 1.01 08 0.802 10. 5.1 (5. 6. 2.67 (2.67 8.10 (8.10± 22.04 (22.04 12.29 (12.29± 21. (21 −0.5 (−0. 0.7 (0. 0.62 (0.6 0.50 1.0 0.80 5. (5 2.6 (2.6 8.1 (8.10 22.0 (22.0 12.2 (12.29 (2 −0. (−0 0. (0 0.6 0.5 1. 0.8 ( 2. (2. 8. (8.1 22. (22. (12.2 −0 (− (8. (22 (12. − (8 (12 (1
14.
Structure and mechanical behavior of lignosulfonate-treated piassava (Attalea funifera) fibers lignosulfonatetreated lignosulfonate treated Attalea funifera
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Agrize, Paula Lage
; da Silva, Beatriz Dantas Lourenço
; Carvalho Veiga, Betina
; Rocha, Camila Aparecida Abelha
; Garcia Filho, Fabio da Costa
; Braga, Fábio de Oliveira
.
ABSTRACT The use of natural lignocellulosic fiber (NLF) biocomposites for the construction industry has been growing over the years, due to technical and environmental advantages. However, fiber-matrix incompatibility remains a major challenge. Various surface treatments have been investigated to improve fiber-matrix bonding, including sodium lignosulfonate (SLS), a potentially effective and environmentally friendly chemical. In this study, SLS treatment protocols were applied to piassava fibers to evaluate their influence on the fibers. Thermogravimetric Analysis (TG/DTG), X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM/EDS), Fourier-transform Infrared Spectroscopy (FTIR), moisture absorption measurements and tensile tests were performed to characterize the modifications. Results demonstrated, for the first time, the efficiency of SLS to remove extractives from the piassava surface. In general, partial degradation of the cellulosic structure was observed, noticeable by the slight drop in crystallinity index (from 42.80 to 39.82%), and an increase in the TG residual mass (from 21.35 to 31.90%), along with changes in DTG curves. However, a particular SLS treatment using ultrasonic bath was able to fully clean the surface preserving the cellulosic structure, and increasing the strength of fibers (from 386 ± 140 MPa to 524 ± 126 MPa). NLF (NLF years advantages However fibermatrix matrix challenge bonding SLS, , (SLS) chemical study TG/DTG, TGDTG TG/DTG (TG/DTG) Xray X ray XRD, XRD (XRD) SEM/EDS, SEMEDS SEM/EDS SEM EDS (SEM/EDS) Fouriertransform Fourier transform FTIR, FTIR (FTIR) modifications demonstrated time general observed 4280 42 80 42.8 39.82%, 3982 39.82% 39 82 39.82%) 2135 21 35 21.3 31.90%, 3190 31.90% 31 90 31.90%) curves 38 14 52 12 MPa. . MPa) (SLS (TG/DTG (XRD (SEM/EDS (FTIR 428 4 8 42. 398 39.82 3 213 2 21. 319 31.90 9 1 5 39.8 31.9 39. 31.
15.
Effects of specific hypnotic suggestions on mechanical and thermal sensitivity of healthy volunteers: randomized and double-blind study volunteers doubleblind double blind
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Oliveira, Victória Regina da Silva
; Oliveira, Inaeh de Paula
; Eng, Beatriz Magalhães
; Teixeira, Manoel Jacobsen
; Puentes, Fabio
; Dale, Camila Squarzoni
.
RESUMO JUSTIFICATIVA E OBJETIVOS: Sugestões hipnóticas de hipoalgesia ou analgesia são eficientes para aliviar diferentes quadros álgicos, apresentando poucos ou nenhum efeito colateral. No entanto, pouco se sabe sobre seu efeito direto na modulação da nocicepção periférica. O objetivo deste estudo foi avaliar a resposta mecânica e térmica após sugestões hipnóticas específicas em voluntários saudáveis. MÉTODOS: Este é um estudo randomizado e duplo-cego que visou avaliar a nocicepção mecânica e térmica após sugestões hipnóticas específicas em voluntários saudáveis. Para isso, vinte e sete participantes foram selecionados, de acordo com os seguintes critérios de elegibilidade: idade entre 18 e 65 anos e ausência de distúrbios psicológicos e de queixas de dor. Após a assinatura do Termo de Consentimento Livre e Esclarecido (TCLE), os participantes foram divididos por randomização gerada por computador em três grupos: grupo sham (sem indução de hipnose), grupo dor induzida por hipnose e grupo analgesia induzida por hipnose. A suscetibilidade à hipnose foi avaliada através da escala Waterloo-Stanford Group C (WSGC) de suscetibilidade hipnótica e os resultados incluíram a avaliação de questionários (Escala Hospitalar de Ansiedade e Depressão e Inventário Breve de Dor), bem como o exame de nocicepção mecânica e térmica através do Teste Sensorial Quantitativo (QST), uma ferramenta amplamente utilizada para investigar a sensibilidade somatossensorial por meio da avaliação das funções das fibras sensoriais finas dos nervos A-δ e C, antes e após sugestão hipnótica específica para dor e analgesia aplicada por um hipnoterapeuta qualificado. RESULTADOS: Os dados mostraram que as sugestões hipnóticas específicas induziram mudanças significativas na sensibilidade mecânica e térmica dos indivíduos. O grupo dor revelou aumento da hiperalgesia mecânica e da alodinia, enquanto o grupo analgesia aumentou os limiares de dor por estímulos térmicos, sendo condicionado a suportar mudanças de temperatura após a hipnose, demonstrando efeito modulador tanto para as sensações de dor quanto de analgesia em voluntários saudáveis. CONCLUSÃO: As evidências apresentadas neste estudo sustentam o uso da técnica de hipnose como ferramenta auxiliar na prática clínica. DESTAQUES Sugestões hipnóticas específicas podem modular a nocicepção periférica em sujeitos saudáveis. Os dados mostram um efeito modulador tanto para as sensações de dor quanto de analgesia. A hipnose pode ser considerada uma técnica viável para o manejo clínico da dor. OBJETIVOS álgicos colateral entanto saudáveis MÉTODOS duplocego duplo cego isso selecionados elegibilidade 1 6 TCLE, TCLE , (TCLE) grupos sem hipnose) WaterlooStanford Waterloo Stanford WSGC (WSGC Escala Dor, Dor Dor) QST, QST (QST) Aδ δ qualificado RESULTADOS indivíduos alodinia térmicos CONCLUSÃO clínica (TCLE (QST
ABSTRACT BACKGROUND AND OBJECTIVES: Hypnotic suggestions for hypoalgesia or analgesia are efficient for relieving different pain conditions, presenting few or no side effects. However, little is known about its direct effect on the modulation of peripheral nociception. The goal of this study was to evaluate the mechanical and thermal response after specific hypnotic suggestions in healthy volunteers. METHODS: This is a randomized double-blinded controlled trial that aimed to evaluate both mechanical and thermal nociception after specific hypnotic suggestions in healthy volunteers. For this, twenty-seven participants were enrolled, according to the following eligibility criteria: age between 18-65 years and absence of pain complaints or psychological disorders. After signed Free Informed Consent Term (FICT) the participants were divided by a computer-generated randomization in three groups: sham group (no induction of hypnosis), hypnosis-induced pain group and hypnosis-induced analgesia group. Susceptibility to hypnosis was assessed through the Waterloo-Stanford Group C (WSGC) scale of hypnotic susceptibility and outcomes included evaluation of questionnaires (Hospital Anxiety and Depression Scale and Short Form Brief Pain Inventory) as well as the examination of mechanical and thermal nociception through the Quantitative Sensory Testing (QST), a tool widely used to investigate somatosensory sensitivity by assessing functions of small A-δ and C nerve sensory fibers, before and after specific hypnotic suggestion for pain and analgesia made by a qualified hypnotherapist. RESULTS: Data demonstrated that specific hypnotic suggestions induced significant changes in mechanical and thermal sensitivity. The pain group revealed an increase in mechanical hyperalgesia and allodynia, while the analgesia group increased pain thresholds to thermal stimulations, being conditioned to withstand temperature changes after hypnosis, demonstrating a modulatory effect for both pain and analgesia sensations in healthy volunteers. CONCLUSION: The evidence presented in this study supports the use of the hypnosis technique as an auxiliary tool in clinical practice. HIGHLIGHTS Specific hypnotic suggestions can modulate peripheral nociception in healthy subjects. Data show a modulatory effect for both pain and analgesia sensations. Hypnosis can be considered a feasible technique for the clinical pain management. OBJECTIVES conditions effects However volunteers METHODS doubleblinded double blinded twentyseven twenty seven enrolled criteria 1865 18 65 18-6 disorders FICT (FICT computergenerated computer generated groups , hypnosis) hypnosisinduced WaterlooStanford Waterloo Stanford WSGC (WSGC Hospital Inventory QST, QST (QST) Aδ A δ fibers hypnotherapist RESULTS allodynia stimulations CONCLUSION practice subjects management 186 1 6 18- (QST
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