Pesquisa | SciELO

Este estudio examinó la producción del cuidado en los servicios de salud, adoptando la metodología participativa “río de la vida”. Realizado en una comunidad que vive a la orilla de un río en el interior de estado de Amazonas, la investigación utilizó ese abordaje reflexivo, envolviendo la creación de un río con materiales artísticos, tales como lápices de colores, cartulina y otros. La técnica promovió la proximidad con las historias, trayectorias y el empoderamiento de agentes comunitarios, usuarios y cuidadores. Esa experiencia profunda proporcionó insights sobre los desafíos territoriales en el acceso a la salud en situaciones urgentes. La grabación de las narrativas durante trabajos colectivos sirvió como método de colecta de datos, facilitando el diálogo entre el equipo de salud y cuidadores, enriqueciendo la comprensión de las dinámicas regionales envueltas en el cuidado de emergencia. vida. vida . vida” Amazonas reflexivo artísticos colores otros historias comunitarios cuidadores urgentes datos emergencia

This study examined the production of care in healthcare services, adopting the participatory methodology “river of life”. Conducted in a riverside community in the interior of the Amazonas region, the research employed this reflective approach, involving the creation of a river using artistic materials such as colored pencils and cardboard. The technique fostered closeness with the stories, trajectories, and empowerment of community agents, users, and caregivers. This profound experience provided insights into the territorial challenges in accessing healthcare during urgent situations. Recording narratives during collective work sessions served as a data collection method, facilitating dialogue between the healthcare team and caregivers, enriching the understanding of regional dynamics involved in emergency care. services life. life . life” region approach cardboard stories trajectories agents users caregivers situations method

Este estudo examinou a produção do cuidado nos serviços de saúde, adotando a metodologia participativa “rio da vida”. Realizado em uma comunidade ribeirinha no interior do Amazonas, a pesquisa utilizou essa abordagem reflexiva, envolvendo a criação de um rio com materiais artísticos, como lápis coloridos e cartolina. A técnica promoveu a proximidade com as histórias, trajetórias e empoderamento de agentes comunitários, usuários e cuidadores. Essa experiência profunda proporcionou insights sobre os desafios territoriais no acesso à saúde em situações urgentes. A gravação das narrativas durante os trabalhos coletivos serviu como método de coleta de dados, facilitando o diálogo entre a equipe de saúde e cuidadores; e enriquecendo a compreensão das dinâmicas regionais envolvidas no cuidado emergencial. vida. vida . vida” Amazonas reflexiva artísticos cartolina histórias comunitários cuidadores urgentes dados emergencial

https://doi.org/10.1590/interface.230649

Navegando pelo “rio da vida”: a produção do cuidado em situações de urgência e emergência em um território da Amazônia
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Reis, Ana Elizabeth Sousa

; Schweickardt, Julio Cesar

; Guedes, Thalita Renata Oliveira das Neves

; Santos, Izi Caterini Paiva Alves Martinelli dos

; Murta, Sheila Giardini

Interface - Comunicação, Saúde, Educação

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2024, Volume 28 elocation e230649

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

https://doi.org/10.1590/interface.230649

Assessment of sexual and body esteem in postpartum women with or without perineal laceration: a cross-sectional study with cultural translation and validation of the Vaginal Changes Sexual and Body Esteem Scale laceration crosssectional cross sectional
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de Souza, Renata Stefânia Olah

; Luz, Adriana Gomes

; Zielinski, Ruth

; Sarian, Luis Otavio Zanatta

; Juliato, Cassia Raquel Teatin

; Lara, Lucia Alves da Silva

; Brito, Luiz Gustavo Oliveira

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo35

Resumo: En | Texto: En | PDF: En

Objective: We aimed to translate and determine cultural validity of the Vaginal Changes Sexual and Body Esteem Scale (VSBE) for Brazilian Portuguese language in postpartum women who underwent vaginal delivery with or without perineal laceration and cesarean section. Methods: A cross-sectional study conducted virtually, with online data collection through a survey with 234 postpartum women of 975 that were invited. Clinical, sociodemographic, and psychometric variables from the VSBE questionnaire were analyzed (content validity index, internal consistency, test-retest reliability, construct/structural and discriminant validity). Multivariate analysis was performed to explore associated factors with the presence of perineal laceration. Results: One-hundred fifty-eight women experienced vaginal delivery, of which 24.79% had an intact perineum, 33.33% had perineal laceration, and 9.4% underwent episiotomy; and 76 participants had cesarean sections. Women with perineal laceration were older, presented dyspareunia and previous surgeries than women without perineal laceration (p<0.05). For VSBE, a high internal consistency (Cronbach's α > 0.7) was observed, but it did not correlate with Body Attractiveness Questionnaire and Female Sexual Function Index; however, it correlated with the presence of women sutured for perineal laceration. Moreover, VSBE presented good structural validity with two loading factors after exploratory factor analysis. VSBE also demonstrated discriminant validity between the presence or absence of perineal laceration. The presence of urinary incontinence (UI) (OR=2.716[1.015-4.667];p=0.046) and a higher VSBE total score (OR=1.056[1.037-1.075];p<0.001) were the only factors associated with perineal laceration. Conclusion: Vaginal Changes Sexual and Body Esteem Scale demonstrated appropriate translation and good internal consistency, discriminant/construct validity and reliability. Vaginal Changes Sexual and Body Esteem Scale total score and presence of UI were associated with women that underwent perineal laceration. Objective (VSBE section Methods crosssectional cross sectional virtually 23 97 invited Clinical sociodemographic content index testretest test retest reliability constructstructural construct validity. . validity) Results Onehundred One hundred fiftyeight fifty eight 2479 24 79 24.79 perineum 3333 33 33.33 94 9 4 9.4 episiotomy 7 sections older p<0.05. p005 p p<0.05 0 05 (p<0.05) Cronbachs Cronbach s 0.7 07 observed Index however Moreover (UI OR=2.7161.0154.667p=0.046 OR271610154667p0046 ORp OR=2.716 1.015 4.667 p=0.046 OR 2 716 1 015 667 046 (OR=2.716[1.015-4.667];p=0.046 OR=1.0561.0371.075p<0.001 OR105610371075p0001 OR=1.056 1.037 1.075 p<0.001 056 037 075 001 (OR=1.056[1.037-1.075];p<0.001 Conclusion discriminantconstruct 247 24.7 333 3 33.3 9. p00 p<0.0 (p<0.05 0. 7161 0154 667p OR=2.7161.0154.667p=0.04 OR271610154667p004 OR2716 OR=2.71 1015 1.01 4667 4.66 p0046 p=0.04 71 01 66 04 (OR=2.716[1.015-4.667];p=0.04 0561 0371 075p OR=1.0561.0371.075p<0.00 OR105610371075p000 OR1056 OR=1.05 1037 1.03 1075 1.07 p0001 p<0.00 03 00 (OR=1.056[1.037-1.075];p<0.00 24. 33. p0 p<0. (p<0.0 OR=2.7161.0154.667p=0.0 OR271610154667p00 OR271 OR=2.7 101 1.0 466 4.6 p004 p=0.0 6 (OR=2.716[1.015-4.667];p=0.0 OR=1.0561.0371.075p<0.0 OR105610371075p00 OR105 OR=1.0 103 107 p000 (OR=1.056[1.037-1.075];p<0.0 p<0 (p<0. OR=2.7161.0154.667p=0. OR271610154667p0 OR27 OR=2. 10 1. 46 4. p=0. (OR=2.716[1.015-4.667];p=0. OR=1.0561.0371.075p<0. OR105610371075p0 OR10 OR=1. (OR=1.056[1.037-1.075];p<0. p< (p<0 OR=2.7161.0154.667p=0 OR271610154667p OR2 OR=2 p=0 (OR=2.716[1.015-4.667];p=0 OR=1.0561.0371.075p<0 OR105610371075p OR1 OR=1 (OR=1.056[1.037-1.075];p<0 (p< OR=2.7161.0154.667p= OR= p= (OR=2.716[1.015-4.667];p= OR=1.0561.0371.075p< (OR=1.056[1.037-1.075];p< (p OR=2.7161.0154.667p (OR=2.716[1.015-4.667];p OR=1.0561.0371.075p (OR=1.056[1.037-1.075];p

https://doi.org/10.61622/rbgo/2024rbgo35

Mitochondrion genomes of seven species of the endangered genus Sporophila (Passeriformes: Thraupidae) Passeriformes (Passeriformes Thraupidae
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Melo-Ximenes, Amanda Alves de

; Corvalán, Leonardo Carlos Jeronimo

; Carvalho, Larissa Resende

; Mangini, Thalita Alves

; Sobreiro, Mariane Brom

; Vieira, Lucas Donizetti

; Dias, Renata de Oliveira

; Silva Neto, Carlos de Melo e

; Telles, Mariana Pires de Campos

; Nunes, Rhewter

Genetics and Molecular Biology

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2024, Volume 47 Nº 1 elocation e20230172

Resumo: En | Texto: En | PDF: En

Abstract We announce the mitochondrial genomes of seven species of the genus Sporophila (S. bouvreuil, S. iberaensis, S. melanogaster, S. minuta, S. nigrorufa, S. pileata, and S. ruficollis) which were validated by comparative genomic and phylogenetic analysis with related species. The mitochondrial genomes of seven passerines of the genus Sporophila were assembled (three complete and four nearly complete genomes) and were validated by reconstructing phylogenetic relations within Thraupidae. The complete mitogenomes ranged from 16,781 bp in S. ruficollis to 16,791 bp in S. minuta. We identified a conserved genome composition within all mitogenomes with 13 protein-coding genes, 22 tRNAs and two rRNAs. We observed a bias in the nucleotide composition and six mutational hotspots in Sporophila mitogenomes. Our mitogenome-based phylogenetic tree has S. minuta, S. maximiliani and S. nigricollis as sister species of the remaining species in the genus. We present new mitogenome sequences for seven Sporophila species, providing new genomic resources that may be useful for research on the evolution, comparative genetics, and conservation of this threatened group. S (S bouvreuil iberaensis melanogaster minuta nigrorufa pileata three Thraupidae 16781 16 781 16,78 16791 791 16,79 1 proteincoding protein coding genes 2 rRNAs mitogenomebased based evolution genetics group 1678 78 16,7 1679 79 167 7 16,

https://doi.org/10.1590/1678-4685-gmb-2023-0172

Effect of curcumin and three analogues on pre-osteoblast cells’ viability, differentiation, and gene expression preosteoblast pre osteoblast cells viability differentiation
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Sá, Ana Flor

; Diniz, Ivana Márcia Alves

; Oliveira, Renata Barbosa de

; Diniz, Marina Gonçalves

; Cortés, Maria Esperanza

; Souza, Letícia Lopes de

; Olórtegui, Carlos Delfin Chávez

; Lages, Frederico Santos

Brazilian Oral Research

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2024, Volume 38 elocation e123

Resumo: En | Texto: En | PDF: En

Abstract Curcumin, found in turmeric rhizomes (Curcuma longa L.), has been widely studied for its potential health benefits, including anti-inflammatory, antioxidant, and wound-healing properties. However, due to its low bioavailability and unfavorable pharmacokinetics, analogous compounds have been developed to obtain better biopharmaceutical characteristics and enhanced biological effects. In this study, we evaluated the activity of curcumin and three of its synthetic analogues (DMAD, DMAM, and RI75) on the viability and differentiation of a pre-osteoblastic cell line (MC3T3-E1). We also assessed the expression of key genes involved in tissue regeneration: vascular endothelial growth factor (vegf), stromal-derived growth factor 1 (SDF-1/CXCL12), and runt-related transcription factor 2 (runx2). The cells were treated with curcumin and the three analogues at concentrations of 10, 30, or 50 μM. All tested analogues and curcumin exhibited moderate to no cell toxicity compared to the cells treated under standard conditions across all concentrations after 24, 48, and 72 hours. Only the RI75 analogue showed upregulation of SDF-1, a crucial factor in tissue regeneration. Compared to curcumin, the DMAM and RI75 analogues also upregulated runx2 and vegf, both associated with osteodifferentiation. The RI75 analogue demonstrated greater mineralization than curcumin, and both promoted more nodule formation than the untreated control. Our data suggest that the curcumin analogue RI75 at 50 μM presents similar toxicity but enhanced biological activity compared to natural curcumin, making it a promising substance for material biomodifications. Curcumin Curcuma L., L L. , L.) benefits antiinflammatory, antiinflammatory anti inflammatory, inflammatory anti-inflammatory antioxidant woundhealing wound healing properties However pharmacokinetics effects study DMAD, DMAD (DMAD RI preosteoblastic pre osteoblastic MC3T3E1. MC3T3E1 MCTE MC3T3 E1 . MC T E (MC3T3-E1) regeneration vegf (vegf) stromalderived stromal derived SDF1/CXCL12, SDF1CXCL12 SDFCXCL SDF 1/CXCL12 CXCL12 CXCL (SDF-1/CXCL12) runtrelated runt related runx2. runx (runx2) 10 30 5 24 48 7 hours RI7 SDF1, SDF1 1, SDF-1 osteodifferentiation control biomodifications MC3T3E MCT MC3T (MC3T3-E1 (vegf SDF1/CXCL12 SDF1CXCL1 1CXCL12 1/CXCL1 CXCL1 (SDF-1/CXCL12 (runx2 3 4 SDF- (MC3T3-E SDF1/CXCL1 SDF1CXCL 1CXCL1 1/CXCL (SDF-1/CXCL1 (runx SDF1/CXCL 1CXCL (SDF-1/CXCL

https://doi.org/10.1590/1807-3107bor-2024.vol38.0123

A newly bat-borne hantavirus detected in Seba’s short-tailed bats (Carollia perspicillata) in the Brazilian Atlantic Rainforest batborne bat borne Sebas Seba s shorttailed short tailed Carollia perspicillata
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Souza, Patrick Jesus de

; Fernandes, Jorlan

; Coelho, Thayssa Alves

; Cosentino, Matheus

; D’arc, Mirela

; Alves, Patrícia Dias Galvão

; Guterres, Alexandro

; Vilar, Emmanuel Messias

; Lemos, Elba Regina Sampaio de

; Cordeiro-Estrela, Pedro

; Santos, André Felipe Andrade

; Oliveira, Renata Carvalho de

Memórias do Instituto Oswaldo Cruz

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2024, Volume 119 elocation e240132

Resumo: En | Texto: En | PDF: En

BACKGROUND Bat-borne hantaviruses have been identified worldwide but little is known about neotropical bats in the megadiverse biomes of the American continent. Although serological evidence has hinted at hantavirus circulation in Brazil, the scarce number of genomic detection represents a gap to understand viral diversity, prevalence, and ecology of bat-borne hantaviruses. OBJECTIVE We aim to investigate and evaluate the presence and prevalence of bat-borne hantavirus in the Brazilian Atlantic Forest. METHODS Here in, 97 lung and kidney tissue samples from bats captured in the Brazilian Atlantic Rainforest were submitted to hantavirus-specific nested reverse transcription-polymerase chain reaction (RT-PCR) targeted the hantaviral L segment and metagenomic analysis. FINDINGS Hantavirus RNA was detected in five tissue fragments of 20 Seba’s short-tailed bats (Carollia perspicillata). Phylogenetic analysis, based on partial L-segment sequence using maximum likelihood method, demonstrated that the identified virus formed a monophyletic clade and a highly divergent bat-borne lineage comprising other recent strains found in the genus Carollia from South America. MAIN CONCLUSIONS Our findings suggest the presence of a novel bat-borne hantavirus in Brazil, tentatively named Mamanguape virus (MGPV). Additional genomic data will help to extend our knowledge about the classification of MGPV within the Hantaviridae family and the evolution origins of new world bat-borne hantaviruses. Batborne Bat borne continent Brazil diversity batborne bat Forest 9 hantavirusspecific specific transcriptionpolymerase transcription polymerase RTPCR RT PCR (RT-PCR analysis 2 Sebas Seba s shorttailed short tailed perspicillata. perspicillata . perspicillata) Lsegment method America MGPV. (MGPV) (MGPV

https://doi.org/10.1590/0074-02760240132

Clinical and epidemiological profiles from a case series of 26 Brazilian CADASIL patients 2
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Nogueira, Renata

; Couto, Christian Marques

; Oliveira, Pérola de

; Martins, Bernardo José Alves Ferreira

; Montanaro, Vinícius Viana Abreu

Arquivos de Neuro-Psiquiatria

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Mai 2023, Volume 81 Nº 5 Páginas 417 - 425

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Antecedentes Arteriopatia cerebral autossômica dominante com enfartes subcorticais e leucoencefalopatia (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy, CADASIL, em inglês) é uma causa genética de acidente vascular cerebral (AVC) isquêmico e a forma mais comum de acidente vascular cerebral não aterosclerótico. Apesar de ser a doença vascular hereditária mais prevalente que há, os dados clínicos para a população brasileira são escassos. Considerando que o Brasil tem uma das constituições genéticas mais heterogêneas do mundo, o conhecimento sobre perfis genéticos e epidemiológicos é obrigatório. Este estudo teve como objetivo elucidar as características clínicas e epidemiológicas de pacientes com CADASIL no Brasil. Métodos Apresentamos uma série de casos envolvendo 6 hospitais de reabilitação no Brasil, e relatamos dados clínicos e epidemiológicos de prontuários de pacientes admitidos entre 2002 e 2019 com confirmação genética. Resultados incluímos 26 pacientes (16 mulheres) em que as mutações nos éxons 4 e 19 eram as mais comuns. A idade média de início da doença foi de 45 anos. O AVC isquêmico foi o primeiro sintoma cardinal em 19 pacientes. Comprometimento cognitivo, demência e manifestações psiquiátricas foram detectados em 17, seis e 16 pacientes, respectivamente. Ao todo, 8 pacientes apresentavam enxaqueca, sendo com aura em 6 (75%) pacientes. Hiperintensidades de substância branca no polo temporal e na cápsula externa foram encontradas em 20 (91%) e 15 pacientes (68%), respectivamente. A pontuação mediana na escala de Fazekas foi de 2. Infartos lacunares, microssangramentos e macro-hemorragias foram observadas em 18 (82%), 9 (41%) e 2 (9%) pacientes, respectivamente. Conclusão O presente estudo representa a mais extensa série de pacientes brasileiros com CADASIL publicada até o momento, e relatamos o primeiro caso de micro-hemorragia na medula espinhal de um paciente com CADASIL. A maior parte dos nossos dados clínicos e epidemiológicos está de acordo com as coortes europeias, exceto para micro-hemorragias e macro-hemorragias, para as quais as taxas se enquadram entre as das coortes europeias e asiáticas. Cerebral Leukoencephalopathy inglês (AVC aterosclerótico há escassos mundo obrigatório 200 201 (1 mulheres 1 comuns anos cognitivo 17 respectivamente todo enxaqueca 75% 75 (75% 91% 91 (91% 68%, 68 68% , (68%) lacunares macrohemorragias macro hemorragias 82%, 82 82% (82%) 41% 41 (41% 9% (9% momento microhemorragia micro hemorragia microhemorragias macrohemorragias, hemorragias, asiáticas ( 7 (75 (91 (68% (82% (41 (9 (7 (68 (82 (4 (6 (8

Abstract Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a genetic cause of ischemic stroke and the most common form of non-atherosclerotic stroke. Despite being the most prevalent vascular hereditary disease, clinical data regarding the Brazilian population are scarce. Considering that the Brazilian population has one of the most heterogeneous genetic constitutions in the world, knowledge about genetic and epidemiological profiles is mandatory. The present study aimed to elucidate the epidemiological and clinical features of CADASIL in Brazil. Methods We performed a case series study comprising 6 rehabilitation hospitals in Brazil and reported the clinical and epidemiological data from the medical records of patients admitted from 2002 to 2019 with genetic confirmation. Results We enrolled 26 (16 female) patients in whom mutations in exons 4 and 19 were the most common. The mean age at the onset of the disease was of 45 years. Ischemic stroke was the first cardinal symptom in 19 patients. Cognitive impairment, dementia, and psychiatric manifestations were detected in 17, 6, and 16 patients respectively. In total, 8 patients had recurrent migraines, with aura in 6 (75%) of them. White matter hyperintensities in the temporal lobe and the external capsule were found in 20 (91%) and 15 patients (68%) respectively. The median Fazekas score was of 2. Lacunar infarcts, microbleeds, and larger hemorrhages were observed in 18 (82%), 9, and 2 patients respectively. Conclusion The present is the most extensive series of Brazilian CADASIL patients published to date, and we have reported the first case of microbleeds in the spinal cord of a CADASIL patient. Most of our clinical and epidemiological data are in accordance with European cohorts, except for microbleeds and hemorrhagic strokes, for which rates fall in between those of European and Asian cohorts. (CADASIL nonatherosclerotic non atherosclerotic scarce world mandatory 200 201 confirmation (1 female 1 years impairment dementia 17 respectively total migraines 75% 75 (75% them 91% 91 (91% 68% 68 (68% 82%, 82 82% , (82%) 9 date patient cohorts strokes ( 7 (75 (91 (68 (82% (7 (9 (6 (82 (8

https://doi.org/10.1055/s-0042-1758756

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

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2023, Volume 37 elocation e126

Resumo: En | Texto: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System. (OMPLs SCC. . (SCC) crosssectional cross sectional North, North (North Northeast CentralWest, CentralWest Central West, West Central-West South. South South) 201 120010 120 010 120,01 20102019, 20102019 , (2010-2019) 69 6 9 6.9 8,321 8321 8 321 (8,32 0.8%, 08 0 (0.8% 95 cases, 4.9%, 49 4 (4.9% 5971 5 971 5,97 1.2%, 12 1 2 (1.2% 1399 399 1,39 Brazils s 64.5%, 645 64.5% 64 (64.5%) located men years level consumption group nonCaucasian non formercurrent former users Institute 99 9.9 Therefore System (SCC 20 12001 01 120,0 2010201 (2010-2019 6. 8,32 832 32 (8,3 0.8% (0.8 4.9% (4.9 597 97 5,9 1.2% (1.2 139 39 1,3 64.5 (64.5% 9. 1200 120, 201020 (2010-201 8,3 83 3 (8, 0.8 (0. 4.9 (4. 59 5, 1.2 (1. 13 1, 64. (64.5 20102 (2010-20 8, (8 0. (0 4. (4 1. (1 (64. (2010-2 ( (64 (2010- (6 (2010 (201 (20 (2

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

Physiological and morphological responses of Arabica coffee cultivars to soil compaction
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Ramos, Elísia Gomes

; Barros, Vanessa Maria de Souza

; Miranda, José Danizete Brás

; Silva, Laís Maria Rodrigues

; Neves, Júlio Cesar Lima

; Meira, Renata Maria Strozi Alves

; Oliveira, Teogenes Senna de

Revista Brasileira de Ciência do Solo

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2023, Volume 47 elocation e0230046

Resumo: En | Texto: En | PDF: En

ABSTRACT Compaction caused by mechanization affects soil quality and, consequently, the development of crops. This study aimed to evaluate the effect of different degrees of soil compaction on the physiology, morphology, and anatomy of different coffee cultivars in a controlled environment. The experiment was carried out in a greenhouse, with randomized block design in a 5 × 5 factorial arrangement, with five coffee cultivars (Arara, Catuaí Amarelo IAC 62, Catuaí Vermelho 144, MGS Paraíso 2 and Mundo Novo IAC 379-19) and five degrees of compaction (68, 74, 80, 86 and 92 %), with four repetitions, totaling 100 experimental units. The following variables were evaluated in the aboveground biomass: plant height, number of leaves, diameter of the orthotropic branch, fresh mass of leaves and stem, leaf area, gas exchange, and chlorophyll a and b index; in the roots: length, surface area, volume, diameter of fine and coarse roots, fresh and dry mass of roots, as well as anatomical characteristics. Results showed that soil with degrees of compaction above 80 % negatively affected the variables evaluated. Catuaí Vermelho 144 presented the worst performance regardless of the degree of compaction, while Arara and MGS Paraíso 2 showed the best performance under the evaluated compaction degrees. Anatomical structure of the roots was modified with soil compaction, and no differences were observed among cultivars. consequently crops physiology morphology environment greenhouse arrangement Arara, (Arara 62 37919 379 19 379-19 68, 68 (68 74 8 9 %, , %) repetitions 10 units biomass height branch stem area exchange index length volume characteristics 14 6 3791 37 1 379-1 (6 7 3 379- (

https://doi.org/10.36783/18069657rbcs20230046

10.

Citopatológico do colo uterino e adequabilidade da amostra: ensaio clínico randomizado controlado amostra
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Freitas, Vívien Cunha Alves de

; Soares, Paula Renata Amorim Lessa

; Nicolau, Ana Izabel Oliveira

; Lima, Thaís Marques

; Pinheiro, Ana Karina Bezerra

Acta Paulista de Enfermagem

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2023, Volume 36 elocation eAPE00972

Resumo: Es Pt En | Texto: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen Objetivo Evaluar dos técnicas de toma de muestra cervicovaginal con la adecuación de la muestra y con los demás resultados del informe colpocitológico. Métodos El estudio fue realizado durante el período de septiembre de 2018 a julio de 2019, en un centro de salud-escuela, ubicado en el municipio de Fortaleza, estado de Ceará. La muestra estaba compuesta por 365 mujeres divididas aleatoriamente, de las cuales 184 participantes estaban en el Grupo Control (técnica por la que el frotis del ectocérvix fue colocado en la lámina antes de la toma del material del endocérvix) y 181 en el Grupo Comparación (en el que el frotis del ectocérvix vaginal fue colocado sobre la lámina únicamente después de la toma del material del endocérvix). Se utilizó un instrumento con variables sociodemográficas, clínicas, sexuales, reproductivas y relativas a los resultados del informe citológico. Fueron incluidas mujeres del grupo de edad de 18 a 64 años, que ya habían empezado su vida sexual y que realizaron la prueba de prevención de cáncer de cuello uterino durante el período de la recopilación de datos. Se utilizaron las pruebas χ2 de Pearson, Fisher y Kruskal-Wallis. Resultados No hubo asociación estadística entre la adecuación de la muestra citológica con las dos técnicas de toma cervicovaginal utilizadas y con las demás variables clínicas, sexuales, reproductivas y referentes a los demás resultados del informe citológico, y se obtuvo un valor de p>5 % en todas las asociaciones realizadas. Conclusión Las dos técnicas de toma de células cervicales que se describen en manuales oficiales no difirieron en la obtención de una muestra celular adecuada y son igualmente eficaces y favorecen la garantía de un informe colpocitológico preciso y oportuno. 201 2019 saludescuela, saludescuela salud escuela, escuela salud-escuela Fortaleza Ceará 36 aleatoriamente técnica endocérvix endocérvix. . sociodemográficas clínicas sexuales citológico 1 6 años datos χ Pearson KruskalWallis. KruskalWallis Kruskal Wallis. Wallis Kruskal-Wallis p5 p 5 p> realizadas oportuno 20 3 2

Resumo Objetivo Avaliar duas técnicas de coleta cervicovaginal à adequabilidade da amostra e aos demais achados do laudo colpocitopatológico. Métodos O estudo foi realizado no período de setembro de 2018 a julho de 2019, em um centro de saúde-escola, localizado no município de Fortaleza - Ceará. A amostra foi composta por 365 mulheres divididas aleatoriamente, sendo 184 participantes no Grupo Controle (técnica na qual o esfregaço da ectocérvice foi disposto na lâmina antes da coleta do material da endocérvice) e 181 no Grupo Comparação (no qual o esfregaço da ectocérvice vaginal foi disposto na lâmina apenas após a coleta do material da endocérvice). Utilizou-se um instrumento contendo variáveis sociodemográficas, clínicas, sexuais, reprodutivas e referentes aos achados no laudo citopatológico. Incluíram-se mulheres na faixa etária de 18 a 64 anos, que já tinham iniciado vida sexual e que realizaram o exame de prevenção do câncer de colo uterino no período da coleta de dados. Os testes do qui-quadrado, Fisher e Kruskal-Wallis foram utilizados. Resultados Não houve associação estatística entre a adequabilidade da amostra citopatológica às duas técnicas de coleta cervicovaginal empregadas e às demais variáveis clínicas, sexuais, reprodutivas e referentes aos demais achados no laudo citopatológico, obtendo-se valor de p>5% em todas as associações realizadas. Conclusão As duas técnicas de coleta de células cervicais descritas em manuais oficiais não diferiram para a obtenção de uma amostra celular adequada, sendo igualmente eficazes e propiciando a garantia de um laudo colpocitopatológico preciso e oportuno. Registro Brasileiro de Ensaios Clínicos (ReBEC): RBR-2H4MPN. 201 2019 saúdeescola, saúdeescola saúde escola, escola saúde-escola Ceará 36 aleatoriamente técnica endocérvice endocérvice. . Utilizouse Utilizou se sociodemográficas clínicas sexuais citopatológico Incluíramse Incluíram 1 6 anos dados quiquadrado, quiquadrado qui quadrado, quadrado qui-quadrado KruskalWallis Kruskal Wallis utilizados obtendose obtendo p5 p 5 p>5 realizadas adequada oportuno ReBEC (ReBEC) RBR2H4MPN. RBR2H4MPN RBRHMPN RBR 2H4MPN. 2H4MPN H MPN RBR-2H4MPN 20 3 p> (ReBEC HMPN 2

Abstract Objective To assess two cervicovaginal collection techniques to sample suitability and the other findings of Pap smear. Methods The study was conducted from September 2018 to July 2019, in a school health center located in the city of Fortaleza - Ceará. The sample consisted of 365 women randomly divided, with 184 participants in the Control Group (technique in which the ectocervix smear was placed on the slide before endocervical material was collected) and 181 in the Comparison Group (in which the vaginal ectocervix smear was placed on the slide only after collecting the material from the endocervix). An instrument containing sociodemographic, clinical, sexual, reproductive and findings in cytopathological report was used. Women aged between 18 and 64 years, who had already started their sexual life and who underwent the cervical cancer prevention test during the data collection period, were included. Chi-square, Fisher and Kruskal-Wallis tests were used. Results There was no statistical association between cytopathological sample suitability for the two cervicovaginal collection techniques used and for the other clinical, sexual, reproductive and other variables related to the other findings in cytopathological report, obtaining a value of p>5% in all associations performed. Conclusion The two techniques for collecting cervical cells described in official manuals did not differ for obtaining an adequate cell sample, being equally effective and providing the guarantee of an accurate and timely Pap smear. Brazilian Clinical Trial Registry (ReBEC): RBR-2H4MPN. 201 2019 Ceará 36 divided technique collected endocervix. endocervix . endocervix) sociodemographic clinical 1 6 years period included Chisquare, Chisquare Chi square, square Chi-square KruskalWallis Kruskal Wallis p5 p 5 p>5 performed ReBEC (ReBEC) RBR2H4MPN. RBR2H4MPN RBRHMPN RBR 2H4MPN. 2H4MPN H MPN RBR-2H4MPN 20 3 p> (ReBEC HMPN 2

https://doi.org/10.37689/acta-ape/2023ao00972

11.

Smart Cabin Design Concept for Regional Aircraft: Challenges, Future Aspects & Requirements Aircraft Challenges
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Silva, Eduardo Leite Simões e

; Moraes, Alison de Oliveira

; Ciaccia, Flávia Renata Dantas Alves Silva

Journal of Aerospace Technology and Management

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2023, Volume 15 elocation e1923

Resumo: En | Texto: En | PDF: En

ABSTRACT New technologies are increasingly being implemented in people’s daily lives and with the growth of smart devices around the globe, the users’ needs and demands have changed in favor of more technological cities, cars, houses, and airplanes. Therefore, it is important to define the stakeholder’s needs and requirements to understand which technologies, smart or not, can be implemented on the cabin to support or even fulfill stakeholder needs. Consequently, those technologies enhance airplane operation and increase product competitiveness for airlines. This paper is the first of a two-part series where design thinking tools are applied to establish high-level requirements based on the concept of a “Smart Cabin” for regional airplanes from 60 to 120 seats. To achieve this goal, a series of methods such as stakeholders’ studies, personas creation and user journey methods are used. The Smart Cabin concept aims to enhance the passenger experience by granting a new level of cabin comfort, customization and connectivity that allows the reduction of airplane time on ground because of the real-time monitoring of airplane cabin components that enables the prediction of maintenance procedures, creates new profits and revenues opportunities for services, provides a more sustainable airplane operation and derived services, and creates new business opportunities for all companies that integrate regional aviation ecosystem. peoples people s globe users cities cars houses Therefore stakeholders not Consequently airlines twopart two part highlevel high 6 12 seats goal studies used comfort realtime real procedures services ecosystem 1

https://doi.org/10.1590/jatm.v15.1309

12.

Smart Cabin Design Concept for Regional Aircraft: Technologies, Applications & Architecture Aircraft Technologies
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Silva, Eduardo Leite Simões e

; Moraes, Alison de Oliveira

; Ciaccia, Flávia Renata Dantas Alves Silva

Journal of Aerospace Technology and Management

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2023, Volume 15 elocation e2023

Resumo: En | Texto: En | PDF: En

ABSTRACT The use of smart devices is driving the growth of modern systems markets, resulting in more technological cities, cars, houses, and airplanes. Therefore, it is important to understand which smart technologies can support or even fulfill stakeholder needs and consequently enhance airplane operation and increase product competitiveness for airlines. This paper is the second of two-part series and has as its main objective the study of smart technologies that can be implemented on cabins of regional airplanes, from 60 to 120 seats, to comply with the needs and requirements pre-established on the first part of this series of articles. The integration of those technologies results in a “Smart Cabin” architecture which its purpose is to enhances the passenger experience by granting a new level of cabin comfort, customization, and connectivity that allows the reduction of airplane time on ground because of the real-time monitoring of airplane cabin components that enables the prediction of maintenance procedures; creates new profits and revenues opportunities for services, provides a more sustainable airplane operation and derived services, and creates new business opportunities for all companies that integrate regional aviation ecosystem. markets cities cars houses airplanes Therefore airlines twopart two 6 12 seats preestablished pre established articles Smart Cabin comfort customization realtime real procedures services ecosystem 1

https://doi.org/10.1590/jatm.v15.1310

13.

Content validity evidence of the Brazilian version of the Cognitive Symptom Checklist-Work-21 ChecklistWork21 ChecklistWork Checklist Work 21 Checklist-Work-2 ChecklistWork2 2 Checklist-Work- Checklist-Work
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Rocha, Elaine Cristina Lopes da

; Sousa, Kayo Henrique Jardel Feitosa

; Lucchesi, Paola Alves de Oliveira

; Faria, Magda Guimarães de Araujo

; Balbinotti, Marcos Alencar Abaide

; Rebustini, Flavio

; Ferretti-Rebustini, Renata Eloah de Lucena

; Gallasch, Cristiane Helena

Revista Brasileira de Enfermagem

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2023, Volume 76 Nº 4 elocation e20220453

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN Objetivo: realizar la adaptación transcultural y evaluar las evidencias de validez de contenido del Cognitive Symptom Checklist-Work-21 para el contexto brasileño. Método: estudio psicométrico de adaptación transcultural, abarcando las etapas de traducción, reconciliación, retrotraducción, evaluación de equivalencia intercultural y análisis de evidencias de validez de contenido, considerando parámetros de Content Validity Ratio en sobrevivientes de cáncer de mama. Resultados: las traducciones fueron equivalentes a la versión original. Se modificaron las expresiones coloquiales, se tensaron, se ajustaron las verbales y se separaron dos ítems que contenían múltiples comandos. La versión final ahora contiene 22 ítems, presentando equivalencia semántica, conceptual, idiomática y experimental. El pre-test indicó buena comprensión y facilidad en el proceso de respuesta. Conclusión: la versión final fue definida como “Lista de verificação de sintomas cognitivos relacionados ao trabalho - 22 itens”, mostrando buena equivalencia lingüística y fuerte evidencia de validez de contenido en el contexto brasileño. Objetivo ChecklistWork21 ChecklistWork Checklist Work 21 Checklist-Work-2 brasileño Método traducción reconciliación retrotraducción mama Resultados original coloquiales tensaron comandos 2 semántica conceptual experimental pretest pre test respuesta Conclusión Lista itens, itens , itens” ChecklistWork2 Checklist-Work- Checklist-Work

ABSTRACT Objective: to cross-culturally adapt and assess the content validity evidence of the Cognitive Symptom Checklist-Work-21 for the Brazilian context. Method: a psychometric study of cross-cultural adaptation, covering the stages of translation, reconciliation, back-translation, intercultural equivalence assessment and content validity evidence analysis, considering Content Validity Ratio parameters in breast cancer survivors. Results: the translations were equivalent to the original version. Colloquial expressions were modified, tense, verbal adjusted, and two items containing multiple commands were separated. The final version now contains 22 items, presenting semantic, conceptual, idiomatic and experimental equivalences. The pre-test indicated good understanding and ease in the response process. Conclusion: the final version was defined as “Lista de verificação de sintomas cognitivos relacionados ao trabalho - 22 itens”, showing good linguistic equivalence and strong evidence of content validity in the Brazilian context. Objective crossculturally cross culturally ChecklistWork21 ChecklistWork Checklist Work 21 Checklist-Work-2 context Method crosscultural cultural adaptation translation reconciliation backtranslation, backtranslation back back-translation analysis survivors Results modified tense adjusted separated 2 semantic conceptual equivalences pretest pre test process Conclusion Lista itens, itens , itens” ChecklistWork2 Checklist-Work- Checklist-Work

RESUMO Objetivo: realizar a adaptação transcultural e avaliar as evidências de validade de conteúdo do Cognitive Symptom Checklist-Work-21 para o contexto brasileiro. Método: estudo psicométrico de adaptação transcultural, abrangendo as etapas de tradução, reconciliação, retrotradução, avaliação de equivalência intercultural e análise das evidências de validade de conteúdo, considerando parâmetros de Content Validy Ratio em sobreviventes de câncer de mama. Resultados: as traduções demonstraram equivalência à versão original. Expressões coloquiais foram modificadas, o tempo verbal ajustado, e dois itens contendo múltiplos comandos foram separados. A versão final passou a conter 22 itens, apresentando equivalências semântica, conceitual, idiomática e experimental. Os valores de CVR mantiveram-se acima de 0,87. O pré-teste indicou boa compreensão e facilidade no processo de resposta. Conclusão: a versão final foi definida como “Lista de verificação de sintomas cognitivos relacionados ao trabalho - 22 itens”, apresentando boa equivalência linguística e fortes evidências de validade de conteúdo no contexto brasileiro. Objetivo ChecklistWork21 ChecklistWork Checklist Work 21 Checklist-Work-2 brasileiro Método tradução reconciliação retrotradução mama Resultados original modificadas ajustado separados 2 semântica conceitual experimental mantiveramse mantiveram se 087 0 87 0,87 préteste pré teste resposta Conclusão Lista , itens” ChecklistWork2 Checklist-Work- 08 8 0,8 Checklist-Work 0,

https://doi.org/10.1590/0034-7167-2022-0453

14.

Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: A multicenter study pointofcare point care Brazil
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Pieri, Otavio Sarmento

; Bezerra, Fernando Schemelzer Moraes

; Coelho, Paulo Marcos Zech

; Enk, Martin Johannes

; Favre, Tereza Cristina

; Graeff-Teixeira, Carlos

; Oliveira, Ricardo Riccio

; Reis, Mitermayer Galvão dos

; Andrade, Lee Senhorinha de Almeida

; Beck, Lilian Christina Nóbrega Holsbach

; Favero, Vivian

; Fialho, Thainá Rodrigues de Souza

; Guimarães, Ricardo José de Paula Souza e

; Oliveira, Bruna Souza Santos

; Pascoal, Vanessa Fey

; Pinheiro, Marta Cristhiany Cunha

; Santos, Ronald Alves dos

; Silva, Luciano Kalabric

; Siqueira, Isadora Cristina de

; Souza, Renata Perotto de

; Katz, Naftale

Revista da Sociedade Brasileira de Medicina Tropical

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2023, Volume 56 elocation e0238-2022

Resumo: En | Texto: En | PDF: En

ABSTRACT Background: The World Health Organization recommends a market-ready, urine-based point-of-care diagnostic test for circulating cathodic antigens (CCA) to determine the prevalence of S. mansoni. This study evaluated the performance of the URINE CCA (SCHISTO) ECO TESTE® (POC-ECO), which is currently available in Brazil. Methods: Residents from eight sites with different prevalence estimates provided one urine sample for POC-ECO and one stool sample for Kato-Katz (KK) and Helmintex® (HTX) testing as an egg-detecting reference for infection status. Results: None of the study sites had significantly higher POC-ECO accuracy than KK. Conclusions: POC-ECO is not currently recommended in Brazilian schistosomiasis elimination programs. Background marketready, marketready market ready, ready market-ready urinebased based pointofcare point care (CCA S mansoni SCHISTO (SCHISTO TESTE POCECO, POCECO POC , (POC-ECO) Brazil Methods KatoKatz Kato Katz KK (KK Helmintex HTX (HTX eggdetecting egg detecting status Results Conclusions programs (POC-ECO

https://doi.org/10.1590/0037-8682-0238-2022

15.

Implementation of a digital tool for population management in Primary Health Care
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Almeida, Debora Paulino da Silva

; Oliveira Junior, Paulo Leandro de

; Prazeres, Glauber Alves dos

; Belotti, Lorrayne

; Domingues, Jessica

; Bonassi, Natalia Martins

; Eshriqui, Ilana

; Martins, Renata Soares

; Almeida, Leticia Yamawaka de

; Bonfim, Daiana

Revista de Saúde Pública

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2023, Volume 57 Supl. 3 elocation 6s

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Descrever a implementação de uma ferramenta digital de diagnóstico e monitoramento territorial na atenção primária à saúde. MÉTODOS Estudo quanti-qualitativo, desenvolvido em 14 Unidades Básicas de Saúde do município de São Paulo, com agentes comunitários de saúde, coordenadores, enfermeiros e médicos. A coleta de dados ocorreu em quatro fases: análise dos instrumentos utilizados pela equipe para gestão do território; desenvolvimento da ferramenta digital; treinamento e implantação; avaliação após 90 dias por meio de grupos focais. Foram realizadas análises descritivas por meio do cálculo de frequências absolutas e relativas para tratamento dos dados quantitativos. Os dados qualitativos foram tratados pela análise de conteúdo. RESULTADOS 334 profissionais participaram do estudo. Na primeira etapa foram identificados como principais desafios para gestão do território o preenchimento de diversos instrumentos, falhas no sistema, inconsistência dos dados, infraestrutura/rede de internet e falta de tempo. Assim, foi desenvolvida uma ferramenta digital composta por: i) planilha com registro do número de membros familiares e marcadores de condições de saúde, data da visita e quantidade de revisitas; ii) planilha com resumo de famílias visitadas, não visitadas e recusas; e iii) um painel com resumo dos dados gerados instantaneamente. Na avaliação, após uso inicial da ferramenta, as temáticas que emergiram foram: integração da ferramenta no cotidiano de trabalho; avaliação do processo de implementação da ferramenta digital; aperfeiçoamento e oportunidades de melhoria. CONCLUSÃO Frente aos desafios encontrados por parte das equipes de saúde da família para preenchimento dos sistemas e gestão do território, a ferramenta desenvolvida proporcionou maior fidedignidade e agilidade na visualização dos dados, redução no volume de instrumentos e otimização do processo de trabalho.

ABSTRACT OBJECTIVE Describe the implementation of a digital diagnostic and territorial monitoring tool in primary healthcare. METHODS Quantitative and qualitative study, developed in 14 basic healthcare units in São Paulo, with community health workers, coordinators, nurses, and physicians. Data collection occurred in four phases: analysis of the instruments used by the team for territory management; development of the digital tool; training and implementation; and evaluation after 90 days using focus groups. Descriptive analyses were conducted by calculating absolute and relative frequencies to treat quantitative data. Qualitative data were subjected to content analysis. RESULTS Three hundred thirty-four professionals participated in the study. In the first step, territory management’s main challenges were filling out various instruments, system failures, data inconsistency, internet infrastructure/network, and lack of time. Therefore, a digital tool was developed consisting of 1) a spreadsheet recording the number of family members and markers of health conditions, date of visit, and number of return visits; 2) a spreadsheet with a summary of families visited, not visited, and refusals; and 3) a panel with a summary of the data generated instantly. In the evaluation, after the initial use of the tool, the themes that emerged were integration of the tool into daily work, evaluation of the digital tool implementation process, and improvement and opportunities for improvement. CONCLUSIONS Faced with the challenges faced by family healthcare teams when filling out systems and managing the territory, the tool developed provided greater reliability and agility in data visualization, reduced the volume of instruments, and optimized the work process.

https://doi.org/10.11606/s1518-8787.2023057005321

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