ABSTRACT Objective To evaluate the prevalence of actinic cheilitis in rural workers and factors associated with the development of this condition. Methods A cross-sectional study was conducted in a city in Northeastern Brazil. Data were collected by clinical examination and use of a questionnaire validated with 300 rural workers. The χ2 test was employed to identify possible associations between the presence of actinic cheilitis and clinical and demographic variables. Multiple logistic regression analysis was performed using forward stepwise selection. A p value of 0.05 was considered significant. Results The prevalence of actinic cheilitis was 12.0% in the sample. The highest prevalence of actinic cheilitis was observed in white males, with low educational level, and an approximately 40-year history of sun exposure. Chronic lesions were commonly found in the lower lip and were characterized by scaling, dryness, and mild edema. Skin color, sex, educational level of patients, and cumulative sun exposure (in years), were identified as predictors of development of actinic cheilitis. Conclusion Our results suggest the need to implement educational health strategies aimed to orient the population about risk factors and preventive measures of the disease. Appropriate clinical management of patients with actinic cheilitis is important for prevention of lip cancer.

Abstract The aim of this study was to identify tumor parenchyma cells exhibiting immunohistochemical profile of stem cells by evaluating the immunoreactivity of OCT4 and CD44 in a number of cases of salivary gland neoplasms. The sample consisted of 20 pleomorphic adenomas, 20 mucoepidermoid carcinomas, and 20 adenoid cystic carcinomas located in major and minor salivary glands. The expression of OCT4 and CD44 was evaluated by the percentage of positive cells and the intensity of expression. All studied cases showed positive expression of OCT4 and CD44 and higher values than the control groups. For OCT4, luminal and non-luminal cells were immunostained in the case of pleomorphic adenomas and adenoid cystic carcinomas. Moreover, the immunoreactivity of CD44 was particularly evident in the non-luminal cells of these lesions. In mucoepidermoid carcinomas, there was immunoreactivity for both markers in squamous and intermediate cells and absence of staining in mucous cells. For both markers, a significantly higher immunostaining was verified in neoplasms located in the major salivary glands compared with lesions in minor salivary glands (p<0.001). In the total sample and in minor salivary glands, malignant neoplasms exhibited higher immunoreactivity for OCT4 than pleomorphic adenoma. A significant moderate positive correlation (r = 0.444 and p ≤ 0.001) was found between OCT4 and CD44 immunoexpression in the total sample. The high expression of OCT4 and CD44 may indicate that these proteins play an important role in identifying tumor stem cells.

RESUMO Objetivo: identificar a prevalência de acidentes motociclísticos envolvendo mototaxistas e fatores associados. Método: estudo transversal e exploratório, com aplicação de questionários aos mototaxistas das 32 praças de Caicó, Rio Grande do Norte, Brasil (N=420). Resultados: os mototaxistas têm alta carga horária de trabalho diária (12 horas em média) e foi verificado que 63,6% já se envolveram em pelo menos um acidente motociclístico. A ocorrência de acidentes motociclísticos foi associada significativamente apenas com escolaridade (p<0,001), não havendo associação significativa com as demais variáveis, tais como idade (p=0,132), tempo de serviço (p=0,744) e carga horária de trabalho (p=0,830). Conclusão: é necessário implementar ações preventivas e educativas com os mototaxistas e usuários do serviço acerca dos acidentes e condutas emergenciais, devido à constante exposição a acidentes durante sua rotina de trabalho.

ABSTRACT Objective: to determine the prevalence of motorcycle accidents involving motorcycle taxi drivers and associated factors. Method: this is a cross-sectional and exploratory study, with application of questionnaires to motorcycle taxi drivers of 32 regions of Caicó, Rio Grande do Norte, Brazil (N=420). Results: motorcycle taxi drivers have a high level of daily working hours (12 hours on average), and it was found that 63.6% were involved in at least one motorcycling accident. The occurence of motorcycling accidents was significantly associated only to level of education (p<0.001), with no significant association with the other variables, such as age (p=0.132), time of service (p=0.744) and working hours (p=0.830). Conclusion: it is necessary to implement preventive and educational actions with motorcycle taxi drivers and users of this service concerning accidents and emergency measures, due to constant exposure to accidents during work routine.

RESUMEN Objetivo: identificar la prevalencia de accidentes motociclísticos involucrando mototaxistas y factores asociados. Método: estudio trasversal y exploratorio, con aplicación de cuestionarios a los mototaxistas de las 32 plazas de Caicó, Rio Grande do Norte, Brasil (N=420). Resultados: los mototaxistas tienen alta carga horaria de trabajo diario (12 horas en media), y se verificó que 63,6% ya se involucraron en por lo menos un accidente motociclístico. La ocurrencia de accidentes motociclísticos se asoció significativamente apenas con escolaridad (p<0,001), no habiendo asociación significativa con las demás variables, tales como edad (p=0,123), tiempo de servicio (p=0,744) y carga horaria de trabajo (p=0,830). Conclusión: es necesario implementar acciones preventivas y educativas con los mototaxistas y usuarios del servicio acerca de los accidentes y conductas emergenciales, debido a la constante exposición a accidentes durante su rutina de trabajo.

ABSTRACT Objective: to determine the prevalence of motorcycle accidents involving motorcycle taxi drivers and associated factors. Method: this is a cross-sectional and exploratory study, with application of questionnaires to motorcycle taxi drivers of 32 regions of Caicó, Rio Grande do Norte, Brazil (N=420). Results: motorcycle taxi drivers have a high level of daily working hours (12 hours on average), and it was found that 63.6% were involved in at least one motorcycling accident. The occurence of motorcycling accidents was significantly associated only to level of education (p<0.001), with no significant association with the other variables, such as age (p=0.132), time of service (p=0.744) and working hours (p=0.830). Conclusion: it is necessary to implement preventive and educational actions with motorcycle taxi drivers and users of this service concerning accidents and emergency measures, due to constant exposure to accidents during work routine.

RESUMEN Objetivo: identificar la prevalencia de accidentes motociclísticos involucrando mototaxistas y factores asociados. Método: estudio trasversal y exploratorio, con aplicación de cuestionarios a los mototaxistas de las 32 plazas de Caicó, Rio Grande do Norte, Brasil (N=420). Resultados: los mototaxistas tienen alta carga horaria de trabajo diario (12 horas en media), y se verificó que 63,6% ya se involucraron en por lo menos un accidente motociclístico. La ocurrencia de accidentes motociclísticos se asoció significativamente apenas con escolaridad (p<0,001), no habiendo asociación significativa con las demás variables, tales como edad (p=0,123), tiempo de servicio (p=0,744) y carga horaria de trabajo (p=0,830). Conclusión: es necesario implementar acciones preventivas y educativas con los mototaxistas y usuarios del servicio acerca de los accidentes y conductas emergenciales, debido a la constante exposición a accidentes durante su rutina de trabajo.

RESUMO Objetivo: identificar a prevalência de acidentes motociclísticos envolvendo mototaxistas e fatores associados. Método: estudo transversal e exploratório, com aplicação de questionários aos mototaxistas das 32 praças de Caicó, Rio Grande do Norte, Brasil (N=420). Resultados: os mototaxistas têm alta carga horária de trabalho diária (12 horas em média) e foi verificado que 63,6% já se envolveram em pelo menos um acidente motociclístico. A ocorrência de acidentes motociclísticos foi associada significativamente apenas com escolaridade (p<0,001), não havendo associação significativa com as demais variáveis, tais como idade (p=0,132), tempo de serviço (p=0,744) e carga horária de trabalho (p=0,830). Conclusão: é necessário implementar ações preventivas e educativas com os mototaxistas e usuários do serviço acerca dos acidentes e condutas emergenciais, devido à constante exposição a acidentes durante sua rotina de trabalho.