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1.
Primary Thrombophilia in Mexico XVIII: Increased Rate of Thrombosis in Persons with the Sticky Platelet Syndrome in the COVID-19 Era
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Melgar-de-la-Paz, Miranda
; Gallardo-Pérez, Moises M.
; Olivares-Gazca, Juan C.
; Ruiz-Argüelles, Guillermo J.
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2.
Programa de telerrehabilitación en pacientes con fractura de radio distal: ensayo clínico controlado
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Pech-Argüelles, Roberto C.
; Miranda-Ortiz, Yetlanezi J.
; Velázquez-Hernández, Hector E.
; Domínguez-Cordero, Rafael
; Ruiz-Pacheco, Cecilia
; Figueroa-García, Juan
; Rojano-Mejía, David
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Abstract Objective: To determine the effectiveness of tele rehabilitation versus supervised treatment in the functional recovery of patients with distal radius fracture. Method: A randomized clinical trial was conducted that included 91 patients with distal radius fractures grades AO23 A and AO23B, which were randomly assigned to a treatment group, the supervised rehabilitation group received for two weeks a program of 10 treatment sessions and the tele rehabilitation group received through the Moodle platform instructions to carry out the rehabilitation program. Outcome measures (functionality, active range of motion, hand grip strength, quality of life and pain) were measured at the time of admission to rehabilitation and at 1, 3 and 6 months. Results: In both treatment groups at 6 months, statistically significant intragroup differences in functionality were demonstrated, with no intergroup differences. Conclusions: At 6 months, both rehabilitation programs increase functionality, range of motion, quality of life and decrease pain, without statistically significant differences intergroup.
Resumen Objetivo: Determinar la efectividad de la telerrehabilitación en comparación con el tratamiento supervisado en la recuperación funcional de los pacientes con fractura de radio distal. Método: Se realizó un ensayo clínico aleatorizado que incluyó 91 pacientes con fracturas de radio distal de grados AO23A y AO23B, los cuales se asignaron aleatoriamente a un grupo de rehabilitación supervisado que recibió durante 2 semanas un programa de 10 sesiones de tratamiento o un grupo de telerrehabilitación que mediante la plataforma de Moodle recibió instrucciones para realizar el programa de rehabilitación. Las medidas de resultado (funcionalidad, rango de movimiento activo, fuerza de prensión de la mano, calidad de vida y dolor) se midieron en el momento del ingreso a rehabilitación y a los 1, 3 y 6 meses. Resultados: A los 6 meses, ambos grupos de tratamiento demostraron diferencias estadísticamente significativas intragrupo en la funcionalidad, sin diferencias intergrupo. Conclusiones: A los 6 meses, ambos programas de rehabilitación aumentan la funcionalidad, el rango de movimiento y la calidad de vida, y disminuyen el dolor, sin diferencias estadísticamente significativas intergrupo.
3.
Diretrizes Brasileiras de Medidas da Pressão Arterial Dentro e Fora do Consultório – 2023 202 20 2
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Feitosa, Audes Diogenes de Magalhães
; Barroso, Weimar Kunz Sebba
; Mion Junior, Decio
; Nobre, Fernando
; Mota-Gomes, Marco Antonio
; Jardim, Paulo Cesar Brandão Veiga
; Amodeo, Celso
; Oliveira, Adriana Camargo
; Alessi, Alexandre
; Sousa, Ana Luiza Lima
; Brandão, Andréa Araujo
; Pio-Abreu, Andrea
; Sposito, Andrei C.
; Pierin, Angela Maria Geraldo
; Paiva, Annelise Machado Gomes de
; Spinelli, Antonio Carlos de Souza
; Machado, Carlos Alberto
; Poli-de-Figueiredo, Carlos Eduardo
; Rodrigues, Cibele Isaac Saad
; Forjaz, Claudia Lucia de Moraes
; Sampaio, Diogo Pereira Santos
; Barbosa, Eduardo Costa Duarte
; Freitas, Elizabete Viana de
; Cestario, Elizabeth do Espirito Santo
; Muxfeldt, Elizabeth Silaid
; Lima Júnior, Emilton
; Campana, Erika Maria Gonçalves
; Feitosa, Fabiana Gomes Aragão Magalhães
; Consolim-Colombo, Fernanda Marciano
; Almeida, Fernando Antônio de
; Silva, Giovanio Vieira da
; Moreno Júnior, Heitor
; Finimundi, Helius Carlos
; Guimarães, Isabel Cristina Britto
; Gemelli, João Roberto
; Barreto-Filho, José Augusto Soares
; Vilela-Martin, José Fernando
; Ribeiro, José Marcio
; Yugar-Toledo, Juan Carlos
; Magalhães, Lucélia Batista Neves Cunha
; Drager, Luciano F.
; Bortolotto, Luiz Aparecido
; Alves, Marco Antonio de Melo
; Malachias, Marcus Vinícius Bolívar
; Neves, Mario Fritsch Toros
; Santos, Mayara Cedrim
; Dinamarco, Nelson
; Moreira Filho, Osni
; Passarelli Júnior, Oswaldo
; Vitorino, Priscila Valverde de Oliveira
; Miranda, Roberto Dischinger
; Bezerra, Rodrigo
; Pedrosa, Rodrigo Pinto
; Paula, Rogerio Baumgratz de
; Okawa, Rogério Toshiro Passos
; Póvoa, Rui Manuel dos Santos
; Fuchs, Sandra C.
; Lima, Sandro Gonçalves de
; Inuzuka, Sayuri
; Ferreira-Filho, Sebastião Rodrigues
; Fillho, Silvio Hock de Paffer
; Jardim, Thiago de Souza Veiga
; Guimarães Neto, Vanildo da Silva
; Koch, Vera Hermina Kalika
; Gusmão, Waléria Dantas Pereira
; Oigman, Wille
; Nadruz Junior, Wilson
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4.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
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; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
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; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
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; Felix, Márcio
; Oliveira, Marcio L. de
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; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
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; Cohn-Haft, Mario
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; Martins, Marlúcia B.
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ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
5.
[SciELO Preprints] - Brazilian Guidelines for In-office and Out-of-office Blood Pressure Measurement – 2023
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Feitosa, Audes Diógenes de Magalhães
Barroso, Weimar Kunz Sebba
Mion Júnior, Décio
Nobre, Fernando
Mota-Gomes, Marco Antonio
Jardim, Paulo Cesar Brandão Veiga
Amodeo, Celso
Camargo, Adriana
Alessi, Alexandre
Sousa, Ana Luiza Lima
Brandão, Andréa Araujo
Pio-Abreu, Andrea
Sposito, Andrei Carvalho
Pierin, Angela Maria Geraldo
Paiva, Annelise Machado Gomes de
Spinelli, Antonio Carlos de Souza
Machado, Carlos Alberto
Poli-de-Figueiredo, Carlos Eduardo
Rodrigues, Cibele Isaac Saad
Forjaz, Cláudia Lúcia de Moraes
Sampaio, Diogo Pereira Santos
Barbosa, Eduardo Costa Duarte
Freitas, Elizabete Viana de
Cestário , Elizabeth do Espírito Santo
Muxfeldt, Elizabeth Silaid
Lima Júnior, Emilton
Campana, Erika Maria Gonçalves
Feitosa, Fabiana Gomes Aragão Magalhães
Consolim-Colombo, Fernanda Marciano
Almeida, Fernando Antônio de
Silva, Giovanio Vieira da
Moreno Júnior, Heitor
Finimundi, Helius Carlos
Guimarães, Isabel Cristina Britto
Gemelli, João Roberto
Barreto Filho, José Augusto Soares
Vilela-Martin, José Fernando
Ribeiro, José Marcio
Yugar-Toledo, Juan Carlos
Magalhães, Lucélia Batista Neves Cunha
Drager, Luciano Ferreira
Bortolotto, Luiz Aparecido
Alves, Marco Antonio de Melo
Malachias, Marcus Vinícius Bolívar
Neves, Mario Fritsch Toros
Santos, Mayara Cedrim
Dinamarco, Nelson
Moreira Filho, Osni
Passarelli Júnior, Oswaldo
Valverde de Oliveira Vitorino, Priscila Valverde de Oliveira
Miranda, Roberto Dischinger
Bezerra, Rodrigo
Pedrosa, Rodrigo Pinto
Paula, Rogério Baumgratz de
Okawa, Rogério Toshiro Passos
Póvoa, Rui Manuel dos Santos
Fuchs, Sandra C.
Inuzuka, Sayuri
Ferreira-Filho, Sebastião R.
Paffer Fillho, Silvio Hock de
Jardim, Thiago de Souza Veiga
Guimarães Neto, Vanildo da Silva
Koch, Vera Hermina
Gusmão, Waléria Dantas Pereira
Oigman, Wille
Nadruz, Wilson
Hypertension is one of the primary modifiable risk factors for morbidity and mortality worldwide, being a major risk factor for coronary artery disease, stroke, and kidney failure. Furthermore, it is highly prevalent, affecting more than one-third of the global population.
Blood pressure measurement is a MANDATORY procedure in any medical care setting and is carried out by various healthcare professionals. However, it is still commonly performed without the necessary technical care. Since the diagnosis relies on blood pressure measurement, it is clear how important it is to handle the techniques, methods, and equipment used in its execution with care.
It should be emphasized that once the diagnosis is made, all short-term, medium-term, and long-term investigations and treatments are based on the results of blood pressure measurement. Therefore, improper techniques and/or equipment can lead to incorrect diagnoses, either underestimating or overestimating values, resulting in inappropriate actions and significant health and economic losses for individuals and nations.
Once the correct diagnosis is made, as knowledge of the importance of proper treatment advances, with the adoption of more detailed normal values and careful treatment objectives towards achieving stricter blood pressure goals, the importance of precision in blood pressure measurement is also reinforced.
Blood pressure measurement (described below) is usually performed using the traditional method, the so-called casual or office measurement. Over time, alternatives have been added to it, through the use of semi-automatic or automatic devices by the patients themselves, in waiting rooms or outside the office, in their own homes, or in public spaces. A step further was taken with the use of semi-automatic devices equipped with memory that allow sequential measurements outside the office (ABPM; or HBPM) and other automatic devices that allow programmed measurements over longer periods (HBPM).
Some aspects of blood pressure measurement can interfere with obtaining reliable results and, consequently, cause harm in decision-making. These include the importance of using average values, the variation in blood pressure during the day, and short-term variability. These aspects have encouraged the performance of a greater number of measurements in various situations, and different guidelines have advocated the use of equipment that promotes these actions. Devices that perform HBPM or ABPM, which, in addition to allowing greater precision, when used together, detect white coat hypertension (WCH), masked hypertension (MH), sleep blood pressure alterations, and resistant hypertension (RHT) (defined in Chapter 2 of this guideline), are gaining more and more importance.
Taking these details into account, we must emphasize that information related to diagnosis, classification, and goal setting is still based on office blood pressure measurement, and for this reason, all attention must be given to the proper execution of this procedure.
La hipertensión arterial (HTA) es uno de los principales factores de riesgo modificables para la morbilidad y mortalidad en todo el mundo, siendo uno de los mayores factores de riesgo para la enfermedad de las arterias coronarias, el accidente cerebrovascular (ACV) y la insuficiencia renal. Además, es altamente prevalente y afecta a más de un tercio de la población mundial.
La medición de la presión arterial (PA) es un procedimiento OBLIGATORIO en cualquier atención médica o realizado por diferentes profesionales de la salud. Sin embargo, todavía se realiza comúnmente sin los cuidados técnicos necesarios. Dado que el diagnóstico se basa en la medición de la PA, es claro el cuidado que debe haber con las técnicas, los métodos y los equipos utilizados en su realización.
Debemos enfatizar que una vez realizado el diagnóstico, todas las investigaciones y tratamientos a corto, mediano y largo plazo se basan en los resultados de la medición de la PA. Por lo tanto, las técnicas y/o equipos inadecuados pueden llevar a diagnósticos incorrectos, subestimando o sobreestimando valores y resultando en conductas inadecuadas y pérdidas significativas para la salud y la economía de las personas y las naciones.
Una vez realizado el diagnóstico correcto, a medida que avanza el conocimiento sobre la importancia del tratamiento adecuado, con la adopción de valores de normalidad más detallados y objetivos de tratamiento más cuidadosos hacia metas de PA más estrictas, también se refuerza la importancia de la precisión en la medición de la PA.
La medición de la PA (descrita a continuación) generalmente se realiza mediante el método tradicional, la llamada medición casual o de consultorio. Con el tiempo, se han agregado alternativas a través del uso de dispositivos semiautomáticos o automáticos por parte del propio paciente, en salas de espera o fuera del consultorio, en su propia residencia o en espacios públicos. Se dio un paso más con el uso de dispositivos semiautomáticos equipados con memoria que permiten mediciones secuenciales fuera del consultorio (AMPA; o MRPA) y otros automáticos que permiten mediciones programadas durante períodos más largos (MAPA).
Algunos aspectos en la medición de la PA pueden interferir en la obtención de resultados confiables y, en consecuencia, causar daños en las decisiones a tomar. Estos incluyen la importancia de usar valores promedio, la variación de la PA durante el día y la variabilidad a corto plazo. Estos aspectos han alentado la realización de un mayor número de mediciones en diversas situaciones, y diferentes pautas han abogado por el uso de equipos que promuevan estas acciones. Los dispositivos que realizan MRPA o MAPA, que además de permitir una mayor precisión, cuando se usan juntos, detectan la hipertensión de bata blanca (HBB), la hipertensión enmascarada (HM), las alteraciones de la PA durante el sueño y la hipertensión resistente (HR) (definida en el Capítulo 2 de esta guía), están ganando cada vez más importancia.
Teniendo en cuenta estos detalles, debemos enfatizar que la información relacionada con el diagnóstico, la clasificación y el establecimiento de objetivos todavía se basa en la medición de la presión arterial en el consultorio, y por esta razón, se debe prestar toda la atención a la ejecución adecuada de este procedimiento.
A hipertensão arterial (HA) é um dos principais fatores de risco modificáveis para morbidade e mortalidade em todo o mundo, sendo um dos maiores fatores de risco para doença arterial coronária, acidente vascular cerebral (AVC) e insuficiência renal. Além disso, é altamente prevalente e atinge mais de um terço da população mundial.
A medida da PA é procedimento OBRIGATÓRIO em qualquer atendimento médico ou realizado por diferentes profissionais de saúde. Contudo, ainda é comumente realizada sem os cuidados técnicos necessários. Como o diagnóstico se baseia na medida da PA, fica claro o cuidado que deve haver com as técnicas, os métodos e os equipamentos utilizados na sua realização.
Deve-se reforçar que, feito o diagnóstico, toda a investigação e os tratamentos de curto, médio e longo prazos são feitos com base nos resultados da medida da PA. Assim, técnicas e/ou equipamentos inadequados podem levar a diagnósticos incorretos, tanto subestimando quanto superestimando valores e levando a condutas inadequadas e grandes prejuízos à saúde e à economia das pessoas e das nações.
Uma vez feito o diagnóstico correto, na medida em que avança o conhecimento da importância do tratamento adequado, com a adoção de valores de normalidade mais detalhados e com objetivos de tratamento mais cuidadosos no sentido do alcance de metas de PA mais rigorosas, fica também reforçada a importância da precisão na medida da PA.
A medida da PA (descrita a seguir) é habitualmente feita pelo método tradicional, a assim chamada medida casual ou de consultório. Ao longo do tempo, foram agregadas alternativas a ela, mediante o uso de equipamentos semiautomáticos ou automáticos pelo próprio paciente, nas salas de espera ou fora do consultório, em sua própria residência ou em espaços públicos. Um passo adiante foi dado com o uso de equipamentos semiautomáticos providos de memória que permitem medidas sequenciais fora do consultório (AMPA; ou MRPA) e outros automáticos que permitem medidas programadas por períodos mais prolongados (MAPA).
Alguns aspectos na medida da PA podem interferir na obtenção de resultados fidedignos e, consequentemente, causar prejuízo nas condutas a serem tomadas. Entre eles, estão: a importância de serem utilizados valores médios, a variação da PA durante o dia e a variabilidade a curto prazo. Esses aspectos têm estimulado a realização de maior número de medidas em diversas situações, e as diferentes diretrizes têm preconizado o uso de equipamentos que favoreçam essas ações. Ganham cada vez mais espaço os equipamentos que realizam MRPA ou MAPA, que, além de permitirem maior precisão, se empregados em conjunto, detectam a HA do avental branco (HAB), HA mascarada (HM), alterações da PA no sono e HA resistente (HAR) (definidos no Capítulo 2 desta diretriz).
Resguardados esses detalhes, devemos ressaltar que as informações relacionadas a diagnóstico, classificação e estabelecimento de metas ainda são baseadas na medida da PA de consultório e, por esse motivo, toda a atenção deve ser dada à realização desse procedimento.
6.
Demografía y COVID-19: Diferenciales sociales y epidemiológicos
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Aja Díaz, Antonio
; Molina Cintra, Matilde de la Caridad
; Trinquete Díaz, Dixie Edith
; Barros Díaz, Otilia Zenaida
; Rodríguez García, Arianna
; Orbea López, Marbelis
; Mora Pérez, Arelis Rosalen
; Araujo González, Rafael
; Farnós Morejón, Alfonso
; Martin Fernández, Consuelo M.
; Dujarric Bermúdez, Gabriela
; Rodríguez Javiqué, Daylin Cecilia
; Terrero Trinquete, Amanda
; Díaz Fernández, Marta
; Benítez Jiménez, Iliana
; Bourzac Macia, Lisset
; Oliveros Domínguez, Eloy Rafael
; Alfonso de Armas, Marisol
; Quintana Llanio, Livia
; Rodríguez Gómez, Grisell
; Castellanos Cabrera, Roxanne
; Bárcenas Alfonso, Jany
; López Bauta, Adis Aymee
; Oroza Fraíz, Teresa
; Cancio-Bello Ayes, Claudia
; Pérez León, Marta Valeria
; Vera Vergara, Vivian
; Llantá Abreu, María del C.
; Lozano Pérez, Teresa Isabel
; Zas Ros, Bárbara
; Gener Serralta, Sandra
; Rivera Fernández, Rosa M.
; Martínez Debs, Leyti
; Quintosa Puebla, Yissel
; Pérez Rodríguez, Nancy
; Oviedo Álvarez, Vivian
; Fernández Lorenzo, Juan Manuel
; Remond Noa, Ricardo
; Torres Reyes, Antonio
; Veranes Miranda, Alejandro
; de la Garma García, Lic. Diana
.
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Anales de la Academia de Ciencias de Cuba
- Métricas do periódico
ABSTRACT Introduction. The behavior of COVID-19 is influenced by diverse social differentials that transcend demographic variables and include morbidity, the conditions of their homes, family dynamics, job performance, gender roles and stereotypes, care tasks, habits, and behaviors of life and consumption, among others. Methods. Statistical and demographic analysis and tools of metric studies of the information were used. Results and Discussion. The research showed the importance of incorporating into the analysis of the behavior of COVID-19 in Cuba the influence of social and epidemiological differentials determined by skin color, marital status, employment status, income levels, types of families, mobility, hygienic environmental conditions, access to health services, among others, which can place populations in greater or lesser conditions of vulnerability. Conclusions: The composition and dynamics of the population together with other social differentials are determinants of the behavior and expression of the pandemic. The crossing of epidemiological factors with the analysis of containment measures and the composition and structure of the affected population allows for the design of health policies that are more adjusted to the needs of the pandemic. Distance psychological counseling makes it possible to identify and deal with situations related to confinement and changes in life routines that affect the mental health of different groups of people.
RESUMEN Introducción. El comportamiento de la COVID-19 está influenciado por diferenciales sociales que trascienden las variables demográficas e incluyen la morbilidad, las condiciones de sus viviendas, las dinámicas familiares, el desempeño laboral, los roles y estereotipos de género, las tareas de cuidado, los hábitos y comportamientos de vida y consumo, entre otros. Métodos. Se empleó el análisis estadístico y demográfico y herramientas de los estudios métricos. Resultados y Discusión. La investigación mostró la importancia de incorporar a los análisis del comportamiento de la COVID-19 en Cuba la influencia de diferenciales sociales y epidemiológicos determinados por el color de la piel, el estado conyugal, la situación laboral, los niveles de ingreso, los tipos de familias, la movilidad, las condiciones higiénico ambientales, el acceso a los servicios de salud, entre otros, que pueden ubicar a las poblaciones en mayores o menores condiciones de vulnerabilidad. Conclusiones, la composición y la dinámica de la población junto a otros diferenciales sociales son determinantes del comportamiento de la pandemia. El cruzamiento de los factores epidemiológicos con el análisis de las medidas de contención y la composición y estructura de población afectada permite diseñar políticas sanitarias más ajustadas a las necesidades de la pandemia. La orientación psicológica a distancia permite identificar y atender situaciones vinculadas al confinamiento y los cambios en las rutinas de vida que afectan la salud mental de diferentes grupos de personas.
7.
Schwannoma of the dorsal nerve of the penis: case report and differential diagnoses
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Reyes-Esparza, Arturo
; Macias-Flores, Juan C.
; Amaya-Téllez, Mariana
; Miranda-Castañon, Francisco
; Gonzalez-Garcia, Edgardo
.
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Revista médica del Hospital General de México
- Métricas do periódico
Abstract Schwannomas are tumors that appear in the sheath that surrounds the nerves; they are formed of Schwann cells which form the myelin sheath in peripheral nerves. In this document, we report a case of Schwannoma of the dorsal nerve of the penis in a man 40-year-old male with no history of neurofibromatosis. Despite the abundant innervation of the penis, it is rare to find them in this location with < 50 cases reported in the literature. Its diagnosis is integrated based on physical examination and supported by imaging. The definitive diagnosis is obtained with histopathology with immunohistochemistry.
8.
Cistoadenoma ovárico bilateral neonatal, ¿tratamiento conservador o quirúrgico?
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Zenteno Salazar, Emilio
; Escalante Lucero, Edgar
; Valenzuela Dionicio, Carlos
; Miranda Gutiérrez, Orlando
; Hernández Flota, Arsenio
; Méndez Domínguez, Nina
; Núñez Enríquez, Juan C.
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Abstract: Bilateral complex ovarian cysts in newborns are rare and their reporting becomes imperative to in crease knowledge about the best therapeutic management. Objective: To describe the clinical case of a newborn with a diagnosis of bilateral complex ovarian cysts and to discuss the conditions for conservative or surgical management according to the ultrasound characteristics of the cyst. Clinical Case: At 35 weeks of gestational age, prenatal ultrasound identified the presence of cystic masses in both adnexa, so it was decided to interrupt the pregnancy by cesarean section at 37 weeks. After birth, bilateral ovarian cysts of 3.5 x 4.4 x 2.7 and 3.4 x 2.4 x 3.3 cm, right and left, respectively, were corro borated. The right cyst had a septum of 1.4 mm thick and thickened wall of 3 mm which was com patible with complex cysts. On the 4th day of extrauterine life, laparoscopic vacuum aspiration and deroofing with electrocautery of the upper wall of both cysts was performed, without complications. The diagnosis of ovarian serous cystadenoma was made by pathological anatomy. Conclusions: We describe a case with adequate prenatal diagnosis and laparoscopic surgical intervention of a bilateral ovarian cyst > 4 cm. Prenatal diagnosis is essential for choosing the best therapy management (con servative or surgical) depending on the echography characteristics of the cyst. Neonatal surgery is recommended for simple ovarian cysts > 4 cm, complex cysts regardless of their size, and those that become complex cysts during conservative management.
Resumen: Introducción: Los quistes ováricos complejos bilaterales en los recién nacidos son poco frecuentes y su reporte resulta de gran importancia para el conocimiento sobre el mejor manejo terapéutico. Objetivo: Des cribir el caso clínico de una recién nacida con diagnóstico de quistes ováricos complejos bilaterales y discutir las condiciones para el manejo conservador o quirúrgico según las características ecográficas del quiste. Caso Clínico: A las 35 semanas de edad gestacional se identificó mediante ultrasonido pre natal la presencia de masas quísticas en ambos anexos por lo que se decidió interrupción del embara zo por cesárea en la semana 37. Posterior al nacimiento, se corroboró la presencia de quistes ováricos bilaterales de 3,5 x 4,4 x 2,7 y 3,4 x 2,4 x 3,3 cm, derecho e izquierdo, respectivamente. El derecho con tabique de 1,4 mm y pared engrosada de 3 mm, hallazgos compatibles con quistes complejos. Al cuarto día de vida extrauterina se realizó aspiración evacuadora y destechamiento de la pared su perior de ambos quistes con electrocauterio por vía laparoscópica, sin complicaciones. Se realizó el diagnóstico por anatomía patológica de cistoadenoma seroso de ovario. Conclusiones: Describimos un caso con adecuado diagnóstico prenatal e intervención quirúrgica laparoscópica exitosa de quiste ovárico bilateral > 4 cm. El diagnóstico prenatal es fundamental para un abordaje oportuno, según las características ecográficas del quiste: conservador o quirúrgico. Se recomienda la intervención quirúrgica neonatal en quistes de ovario simples > 4 cm, quistes complejos independientemente de su tamaño y aquellos que durante el manejo conservador evolucionen a quistes complejos.
https://doi.org/10.32641/andespediatr.v93i2.3743
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9.
Experiencia en angioplastia percutánea de recoartación de aorta en un solo centro. Resultados a corto, medio y largo plazo
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Fernández-González, Luis
; Alcibar-Villa, Juan
; Blanco-Mata, Roberto
; Arriola-Meabe, Josune
; Román, Koldobika García-San
; Astorga-Burgo, Juan C.
; Acín-Labarta, Aida
; Orive-Melero, Larraitz
; Luis-García, Maite
; Galdeano-Miranda, José M.
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Resumen Introducción: La angioplastia con balón es una técnica que ofrece buenos resultados, especialmente en los casos de recoartación tras cirugía correctora. Objetivo: Analizar los resultados de un centro hospitalario a partir de la introducción de la técnica. Método: Se analizaron 73 pacientes con una edad media de 3.3 años; el 74% eran menores de 1 año y el 72.6% estaban por debajo de 10 kg de peso. Todos los pacientes incluidos fueron casos de recoartación tras cirugía correctora. Resultados: Se observó un resultado efectivo en el 93.1% de los casos, con gradiente residual < 20 mmHg. Durante el seguimiento, el 20.5% precisaron reintervención, la cual fue más frecuente en caso de angioplastia sobre el arco, lesiones asociadas y menores de 1 año. Solo se objetivó una complicación grave relacionada con el procedimiento, que correspondió a una rotura aórtica que no pudo ser solventada con implante de stent cubierto. Conclusiones: La angioplastia percutánea de recoartación de aorta es una técnica segura y efectiva, en especial en los casos de recoartación tras cirugía correctora de lesiones circunscritas al istmo.
Abstract Introduction: Balloon angioplasty is a technique with good outcomes, specially in cases aortic recoartation after correcting surgery. Objective: To analyze our centre results since the introduction of the technique. Method: We analyzed 73 patients with medium age of 3,3 years; 74% were under 1 years old and 72,6% under 10 kg weight. All patients included were cases of recoartation after surgery. Results: Effective results was achieved in 93,1%, obtaining residual gradient less than 20 mmHg. During the following up 20,5% of patients required reintervention, being more frequent in case of aortic arch hypoplasia, associated lesions or patients under 1 year. Only a severe complication was referred, a case of aortic rupture that couldn’t be solved with a covered stent. Conclusions: Percutaneous angioplasty of aortic recoartation is a safe and effective technique, specially in discrete istmic lesions after correcting surgery.
https://doi.org/10.24875/rccar.m22000140
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10.
Aptitud climática para Coffea arabica L. ante eventos climáticos extremos: Importancia de la cobertura arbórea
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Parada-Molina, Paulo César
; Barradas-Miranda, Víctor Luis
; Ortiz Ceballos, Gustavo
; Cervantes-Pérez, Juan
; Cerdán Cabrera, Carlos Roberto
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Abstract Negative impacts of climate change are expected in the production of Coffea arabica L. one of the most commercialized tropical agroproducts in the world. However, most studies work with global circulation models, being of little use in making decisions on the scale of farm management. Given this, the objective of this study was to identify the suitability for the cultivation of C. arabica in the face of climate change and how tree cover mitigates the impacts of climate change in an agroforestry plot. The indices of climatic extremes were calculated (1961 to 2016 for Coatepec; 1985 to 2016 for Briones) and a trend analysis was carried out (Mann-Kendall). The temperature inside a plot, and on an open site, was monitored for two years (2017-2019). This was related to the climatic requirements of C. Arabica. Trends of increase (p < 0.05) of the minimum and minimum extreme annual temperatures were identified in the two stations near the plot (0.24 and 0.69 °C·decade-1 in Coatepec and 0.46 and 0.79 °C·decade-1 in Briones). The maximum temperature did not present significant increases, reducing the thermal amplitude. Both annual and seasonal precipitation shows trends of increase in intensity. All these conditions are still suitable for the cultivation of C. arabica. At the plot scale, the importance of tree cover is demonstrated, which in this agroforestry system allows to reduce the maximum temperature by 1.9 °C compared to an open site. Tree cover has also made it possible to mitigate extreme events.
Resumen Se prevén impactos negativos del cambio climático en la producción de Coffea arabica L. uno de los agroproductos tropicales más comercializados en el mundo. Sin embargo, la mayoría de los estudios trabajan con modelos de circulación global, siendo poco útiles en la toma de decisiones a escala de manejo de una finca. Ante ello, el objetivo de este estudio fue identificar la aptitud para el cultivo de C. arabica ante el cambio climático y cómo la cobertura arbórea mitiga los impactos del cambio climático en una parcela agroforestal. Se calcularon los índices de extremos climáticos (1961 a 2016 para Coatepec; 1985 a 2016 para Briones) y se realizó un análisis de tendencias (Mann-Kendall). Se monitoreó la temperatura en el interior de una parcela, y en un sitio abierto, durante dos años (2017-2019). Esto se relacionó con los requerimientos climáticos de C. arabica. Se identificaron tendencias de incremento (p<0,05) de las temperaturas mínima y mínima extrema anual en las dos estaciones cercanas a la parcela (0,24 y 0,69 °C·década-1 en Coatepec y 0,46 y 0,79 °C·década-1 en Briones). La temperatura máxima no presentó incrementos significativos, reduciendo la amplitud térmica. Tanto la precipitación anual y estacional muestran tendencias de incremento en intensidad. Todas estas condiciones siguen siendo aptas para el cultivo de C. arabica. A escala de parcela, se demuestra la importancia de la cobertura arbórea, que en este sistema agroforestal permite reducir la temperatura máxima 1,9 °C en comparación con un sitio abierto. Asimismo, la cobertura arbórea ha permitido mitigar eventos extremos.
11.
Consenso de leucemia mieloide aguda en México
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Arana-Luna, Luara L.
; Alvarado-Ibarra, Martha
; Silva-Michel, Luis G.
; Morales-Maravilla, Adrián
; González-Rubio, María del C.
; Chávez-Aguilar, Lénica A.
; Tena-Iturralde, María Fernanda
; Mojica-Balceras, Liliana
; Zapata-Canto, Nidia
; Galindo-Delgado, Patricia
; Miranda-Madrazo, María Raquel
; Morales-Hernández, Alba E.
; Silva-Vera, Karina
; Grimaldo-Gómez, Flavio A.
; Hernández-Caballero, Álvaro
; Bates-Martin, Ramón A.
; Álvarez-Vera, José L.
; Tepepa-Flores, Fredy
; Teomitzi-Sánchez, Óscar
; Fermín-Caminero, Denisse J.
; Peña-Celaya, José A. de la
; Salazar-Ramírez, Óscar
; Flores-Villegas, Luz V.
; Guerra-Alarcón, Lidia V.
; Leyto-Cruz, Faustino
; Inclán-Alarcón, Sergio I.
; Milán-Salvatierra, Andrea I.
; Ventura-Enríquez, Yanet
; Pérez-Lozano, Uendy
; Báez-Islas, Pamela E.
; Tapia-Enríquez, Ana L.
; Palma-Moreno, Orlando G.
; Aguilar-Luévano, Jocelyn
; Espinosa-Partida, Arturo
; Pérez-Jacobo, Luis F.
; Rojas-Castillejos, Flavio
; Ruiz-Contreras, Josué I.
; Loera-Fragoso, Sergio J.
; Medina-Coral, Jesús E.
; Acosta-Maldonado, Brenda L.
; Soriano-Mercedes, Emely J.
; Saucedo-Montes, Erick E.
; Valero-Saldana, Luis M.
; González-Prieto, Susana G.
; Nava-Villegas, Lorena
; Hernández-Colin, Ana K.
; Hernández-Alcántara, Areli E.
; Zárate-Rodríguez, Pedro A.
; Ignacio-Ibarra, Gregorio
; Meillón-García, Luis A.
; Espinosa-Bautista, Karla A.
; Ledesma de la Cruz, Cindy
; Barbosa-Loría, Diego M.
; García-Castillo, Carolina
; Balderas-Delgado, Carolina
; Cabrera-García, Álvaro
; Pérez-Zúñiga, Juan M.
; Hernández-Ruiz, Eleazar
; Villela-Peña, Atenas
; Gómez Cortés, Sue Cynthia
; Romero-Rodelo, Hilda
; Garzón-Velásquez, Katheryn B.
; Serrano-Hernández, Cristina
; Martínez-Ríos, Annel
; Pedraza-Solís, María Luisa
; Martínez-Coronel, Jorge A.
; Narváez-Davalos, Iris M.
; García-Camacho, Alinka S.
; Merino-Pasaye, Laura E.
; Aguilar-Andrade, Carolina
; Aguirre-Domínguez, Juan A.
; Guzmán-Mera, Pedro G.
; Delgado-de la Rosa, Elizabeth
; Flores López, Perla E.
; González-Aguirre, Lilia L.
; Ramírez-Alfaro, Edgar M.
; Vera-Calderón, Heidi
; Meza-Dávalos, María Lizeth
; Murillo-Cruz, Juan
; Pichardo-Cepín, Yayra M.
; Ramírez-Romero, Eva F.
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Abstract Acute myeloid leukemia (AML) comprises a heterogeneous group of hematopoietic cell neoplasms of myeloid lineage that arise from the clonal expansion of their precursors in the bone marrow, interfering with cell differentiation, leading to a syndrome of bone marrow failure. AML is a consequence of genetic and epigenetic changes (point mutations, gene rearrangements, deletions, amplifications, and arrangements in epigenetic changes that influence gene expression) in hematopoietic precursor cells, which create a clone of abnormal cells that are capable of proliferating but cannot differentiate into mature hematopoietic cells or undergo programmed cell death. The diagnosis requires more than 20% myeloid blasts in the bone marrow and certain cytogenic abnormalities. Treatment will depend on age, comorbidities, and cytogenetic risk among the most frequent.
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https://doi.org/10.24875/gmm.m21000597
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12.
Growth of provenances of Cryptocarya alba during water stress and after re–watering in the nursery
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Meza, Sergio Enrique Espinoza
; Arce, Marco Aliro Yáñez
; Díaz, Carlos Renato Magni
; Herrera, Eduardo Enrique Martínez
; Ortega, Juan Francisco Ovalle
; Miranda, Suraj Antonio Vaswani
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ABSTRACT: Intensification of drought in Mediterranean–type climates has limited seedling establishment. The knowledge of the ecology of selected species and its intraspecific variation to water stress at the seedling stage should be considered in order to overcome limitations. We investigated variations in growth, survival, and leaf–level physiology in four provenances of the endemic Cryptocarya alba (Mol.) during water stress and after re–watering. Seedlings were cultured in the nursery during 23 months and then subjected to two watering treatments based on soil water content (well–watered and water restriction, 0.38 and 0.17 cm3 cm−3, respectively) for 45 days. At the end of the watering treatments, seedling growth, above– and belowground biomass, survival, and leaf gas exchange were measured. Right after the watering treatments, the surviving seedlings were submitted to a recovery period of 21 days, in which all seedlings were re–watered at 0.38 cm3 cm−3 of soil water content and measured for leaf gas exchange. Provenances differed in growth and biomass allocation. Unlike growth and biomass, interaction between provenance and watering treatments was found for photosynthesis, stomatal conductance, transpiration, and water use efficiency of northern provenances, exhibiting the highest performance under water restriction. However, most variations observed occurred before the re–watering period and only a few occurred after this period. The four provenances under study exhibited similar photosynthesis and stomatal conductance after re–watering. Our study demonstrated phenotypic variation of C. alba and the capability of the species to withstand and recover from water stress.
https://doi.org/10.1590/1678-992x-2020-0292
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13.
La Administración del Agonista mGluR2/3 APDC Disminuye la Señal Discriminativa de la Anfetamina en Ratas
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Cedillo Zavaleta, Laura N.
; Jiménez Mejía, Juan C.
; Ruiz-García, Rosa Isela
; Miranda, Florencio
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Abstract Rewarding, motor and discriminative effects of amphetamine (AMPH) are mediated in large part by increased dopamine (DA) neurotransmission in the nucleus accumbens. However, there is evidence that the glutamate system may regulate forebrain DA function. Here, we examined the role of mGluR2/3 receptors on the discriminative stimulus properties of AMPH using conditioned taste aversion (CTA) as the drug discrimination procedure. Male Wistar rats were deprived of water and trained in the CTA procedure. They received the administration of AMPH (1.0 mg/kg) before a 10 min period of access to saccharin solution and followed by an injection of LiCl; on alternate days, rats received saline (1 ml/kg ip) before and after the access to saccharin solution. In generalization and combination tests, the AMPH was substituted by different doses of the mGluR2/3 receptor agonist (2R,4R)-APDC (0.1, 0.3 and 1.0 mg/kg ip), different doses of the mRGlu2/3 receptor antagonist LY341495 (1.0, 3.0 and 5.6 mg/kg ip), different doses of the mGluR2/3 receptor agonist APDC (0.1, 0.3 y 1.0 mg/kg ip) + AMPH (1.0 mg/kg ip) or different doses of the mGluR2/3 receptor antagonist LY341495 (1.0, 3.0 and 5.6 mg/kg ip) + APDC (1.0 mg/kg ip) + AMPH (1.0 mg/kg ip). The results showed that the agonist APDC significantly decreases the discriminative cue of the AMPH and this effect was reversed by the antagonist LY341495. These data suggest that mGluR2/3 receptors could play an important modulatory role in the discriminative cue of AMPH.
Resumen Los efectos reforzantes, motores y discriminativos de la anfetamina (ANF) están mediados por el incremento en la neurotransmisión de dopamina (DA) en el núcleo accumbens. Existe evidencia de que el sistema Gluérgico podría regular la función DAérgica. Aquí, se examina el papel de los receptores mGluR2/3 en las propiedades discriminativas de la ANF usando el condicionamiento de aversión a los sabores (CAS). Ratas macho de la cepa Wistar fueron privadas de agua y entrenadas con el CAS. Se les administró ANF (1.0 mg/kg ip) antes de un periodo de acceso de 10 min a una solución de sacarina y posteriormente se les administró una inyección de LiCl; en días alternos, se les aplicó una inyección de salina (1 ml/kg ip) antes y después del acceso a la solución de sacarina. En las pruebas de generalización y combinación, la ANF fue substituida por diferentes dosis del agonista mGluR2/3 (2R,4R)-APDC (0.1, 0.3 y 1.0 mg/kg ip), diferentes dosis del antagonista mGluR2/3 LY341495 (1.0, 3.0 y 5.6 mg/kg ip), diferentes dosis de APDC (0.1, 0.3 y 1.0 mg/kg ip) + ANF (1 ml/kg ip) o diferentes dosis de LY341495 (1.0, 3.0 y 5.6 mg/kg ip) + APDC (1.0 mg/kg ip) + ANF (1.0 mg/kg ip). Los resultados mostraron que el agonista APDC disminuyó la señal discriminativa de la ANF y este efecto fue prevenido por el antagonista LY341495. Se sugiere que los receptores mGluR2/3 podrían jugar un papel modulatorio en la señal discriminativa de la ANF.
https://doi.org/10.22201/fpsi.20074719e.2021.1.370
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14.
Recomendaciones para la atención de pacientes con diabetes mellitus con factores de riesgo o enfermedad cardiovascular establecida y SARS-CoV-2
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Alcocer-Gamba, Marco A.
; Gutiérrez-Fajardo, Pedro
; Sosa-Caballero, Alejandro
; Cabrera-Rayo, Alfredo
; Faradji-Hazan, Raquel N.
; Padilla-Padilla, Francisco G.
; Garnica-Cuellar, Juan C.
; Hernández-Arispe, Leticia M.
; Reyes-Cianeros, Fernando A.
; León-Suárez, Andrés
; Rivera, José de-Jesús
; Mancillas-Adame, Leonardo
; Gaxiola-Macias, Manuel
; Márquez-Rodríguez, Eduardo
; Miranda-Malpica, Emma
; Sanchez-Pedraza, Valentín
; Lara-Martínez, Daniel S.
; Segovia-Palomo, Antonio
; Nava-Hernández, Angeles
; Rivera-Reyes, Romina
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Abstract A review is carried out to examine the risk of patients suffering from diabetes mellitus in the context of general morbidity and mortality and related to infection by SARS-CoV-2. Likewise, the general recommendations for food and the prevention of comorbidities that most these patients suffer most frequently are also studied. Finally, a review of the pharmacological recommendations on both oral and parenteral treatment in the outpatient, in hospitalization and in critical states infected with SARS-CoV-2 is made.
Resumen Se realiza una revisión sobre el riesgo de los pacientes que padecen diabetes mellitus en el contexto de morbimortalidad general y relacionada a infección por el coronavirus 2 del síndrome respiratorio agudo grave (SARS-CoV-2). Así mismo se repasan las recomendaciones generales, de alimentación y de la prevención de las comorbilidades que más frecuentemente padecen dichos enfermos. Finalmente se hace una revisión de las recomendaciones farmacológicas sobre el tratamiento tanto oral como parenteral en el paciente ambulatorio, en la hospitalización y en estados críticos infectados por el SARS-CoV-2.
https://doi.org/10.24875/acm.m20000074
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15.
National survey of blindness and visual impairment in Guatemala, 2015
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Chávez, Gloria Marina Serrano
; Barrios, Ana Rafaela Salazar de
; Pojoy, Oscar Leonel Figueroa
; Reyes, Aida del Rosario Monzón Herrera de
; Melgar, Mariano Yee
; Melgar, Juan Francisco Yee
; Régil, Mario de León
; Hernandez, Carlos Alberto Mendoza
; Chanquin, Victor Alfonso Miranda
; Diaz, Evelyn
; Lansingh, Van C.
; Limburg, Hans
; Silva, Juan Carlos
; Furtado, João M.
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RESUMO | Objetivo: Estimar a prevalência de cegueira e deficiência visual em idosos que vivem na Guatemala. Métodos: Indivíduos com idade ³50 anos foram selecionados por amostragem aleatória por conglomerados, e os participantes do estudo foram avaliados pelo método de Avaliação Rápida da Cegueira Evitável. A acuidade visual foi medida e o cristalino foi examinado. Se a acuidade visual apresentada fosse <20/60, então também foi testada com um buraco estenopeico e a fundoscopia realizada. A cegueira e a deficiência visual foram classificadas como deficiência visual moderada com acuidade visual <20/60-20/200; deficiência visual grave com acuidade visual <20/200-20/400; ou cegueira com acuidade visual <20/400. A principal causa de cegueira ou deficiência visual em cada olho foi determinada, e naqueles com catarata, as barreiras ao tratamento foram avaliadas. Resultados: O estudo incluiu 3.850 pessoas com ³50 anos de idade; 3.760 (97,7%) foram examinadas. A prevalência de cegueira ajustada à idade e ao sexo foi de 2,9% (intervalo de confiança de 95%, 2,0-3,8%), 5,2% (4,0-6,4%) deficiência visual grave e 27,6% (23,3-32,0%) deficiência visual moderada. A catarata foi a principal de cegueira (77,6%), seguida de outras doenças do segmento posterior (6,0%). Catarata causada por 79,4% de deficiência visual grave, enquanto erros refrativos não corrigidos causaram 67,9% de deficiência visual moderada. Após a cirurgia de catarata, 75% dos participantes tiveram uma acuidade de 20/200, ou melhor, e 19,0% a deficiência visual não foi melhor do que 20/200 com a correção. O custo foi a principal barreira à cirurgia de catarata (56.7%). Conclusões: A prevalência de cegueira em idosos é maior na Guatemala do que na maioria dos outros países da América Central. A maioria dos casos de cegueira e deficiência visual era evitável ou tratável. O aumento da disponibilidade de tratamento de catarata a preços acessíveis e de alta qualidade teria um impacto substancial na prevenção da cegueira.
ABSTRACT | Purpose: To estimate the prevalence of blindness and visual impairment in older adults living in Guatemala. Methods: Participants ³50 years of age were selected using random cluster sampling and evaluated using the Rapid Assessment of Avoidable Blindness method. Visual acuity was measured, and the lens was examined. If presenting visual acuity was <20/60, it was also tested with a pinhole and fundoscopy was performed. Blindness and visual impairment were classified as moderate visual impairment (presenting visual acuity <20/60 to 20/200), severe visual impairment (presenting visual acuity <20/200 to 20/400), or blindness (presenting visual acuity <20/400). The primary cause of blindness or visual impairment in each eye was determined, and if the cause was cataracts, the barriers to treatment were assessed. Results: The study included 3,850 people ³50 years of age, of whom 3,760 (97.7%) were examined. The age- and sex-adjusted prevalence of blindness was 2.9% (95% confidence interval, 2.0%-3.8%), while 5.2% (4.0%-6.4%) presented with severe visual impairment, and 27.6% (23.3%-32.0%) presented with moderate visual impairment. Cataracts were the leading cause of blindness (77.6%), followed by other posterior segment diseases (6.0%). Cataracts caused 79.4% of cases of severe visual impairment, while uncorrected refractive errors caused 67.9% of cases of moderate visual impairment. Following cataract surgery, 75% of participants had a presenting visual acuity of 20/200 or better, and in 19.0% of participants, visual acuity was not better than 20/200 with correction. Cost was the main barrier to cataract surgery (56.7%). Conclusions: The prevalence of blindness in older adults is higher in Guatemala than in most Central American countries. Most cases of blindness and visual impairment were either preventable or treatable. Increased availability of affordable, high-quality cataract treatment would have a substantial impact on blindness prevention.
https://doi.org/10.5935/0004-2749.20190029
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