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Actualizaciones en el manejo general de pacientes postrasplante hepático y de sus complicaciones más frecuentes
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Díaz, Luis Antonio Villalón, Alejandro Ochoa, Gabriela García, Sergio Severino, Nicolás Ayares, Gustavo Idalsoaga, Francisco Dib, Martin Briceño, Eduardo Viñuela, Eduardo Martinez, Jorge Jarufe, Nicolás Rabagliati, Ricardo Meneses, Luis Muñoz-Schuffenegger, Pablo Vargas, José Ignacio Espino, Alberto Vera, María Magdalena Benítez, Carlos Wolff, Rodrigo Norero, Blanca Barrera, Francisco Soza, Alejandro Arrese, Marco Arab, Juan Pablo

Revista médica de Chile

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Jun 2024, Volume 152 Nº 6 Páginas 704 - 717

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Liver transplantation (LT) is a cost-effective therapy for advanced liver disease. Although LT significantly improves long-term survival, it requires strict control of immunosuppressants and their potential complications. Several available immunosuppressive drugs include glucocorticoids, calcineurin inhibitors, mycophenolate, mTOR inhibitors, and anti-CD25 antibodies. These drugs act particularly in T lymphocytes, depleting them, deviating their traffic, or blocking their response pathways. The main complications after LT include renal failure and infectious, immunological, biliary, vascular adverse events, metabolic, cardiovascular, and neoplastic diseases, especially during the first months. Bacteria, viruses, and fungi can cause infections in these patients. Prophylaxis against Herpes simplex virus, Varicella zoster virus, Cytomegalovirus, Pneumocystis jirovecii, Candida spp., and Aspergillus spp. should be considered according to the presence of risk factors. Among immunological complications, acute cellular rejection is common (30% of LT) but usually responds to immunosuppressive escalation. Also, chronic rejection appears in 3-17% of LT, but only half of the recipients respond to increased immunosuppressants. Appropriate treatment of the underlying etiology is essential, especially in autoimmune diseases, hepatitis B and C virus infection. Lifestyle changes must be encouraged in all patients, and alcohol consumption avoided (especially in alcohol use disorder). Due to the increased risk of cancer, neoplasms must be actively monitored, as well as osteoporosis and other metabolic disorders such as diabetes and cardiovascular disease.

RESUMEN El trasplante hepático (TH) es una terapia costo-efectiva para el tratamiento de las enfermedades hepáticas avanzadas. Aunque el TH mejora significativamente la supervivencia a largo plazo, requiere de un control estricto de la inmunosupresión y de las potenciales complicaciones. Entre los fármacos inmunosupresores destacan los corticoides, inhibidores de calcineurina, micofenolato, inhibidores de mTOR y los anticuerpos anti CD-25. Estos fármacos actúan especialmente sobre los linfocitos T, agotándolos, desviando su tráfico o bloqueando sus vías de respuesta. Las principales complicaciones post TH pueden ser renales, infecciosas, inmunológicas, biliares, vasculares, metabólicas, cardiovasculares y neoplásicas, especialmente los primeros meses post trasplante. Las infecciones son frecuentes y pueden ser causadas por bacterias, virus y hongos. Se debe considerar la profilaxis contra virus Herpes Simple, virus Varicela zoster, Citomegalovirus, Pneumocistys jirovecii, Candida spp. y Aspergillus spp. según la presencia de factores de riesgo. Entre las complicaciones inmunológicas, el rechazo celular agudo es frecuente (30% de los TH), pero habitualmente responde al tratamiento inmunosupresor. Asimismo, el rechazo crónico se presenta en el 3-17% de los TH y solo la mitad responde al incremento de inmunosupresión. El control de las etiologías de base es fundamental, especialmente en enfermedades autoinmunes e infecciones por virus hepatitis B y C. Se deben promover cambios de estilo de vida en todos los pacientes y evitar el consumo de alcohol (especialmente en trastorno por consumo de alcohol). Debido al mayor riesgo de cáncer, se debe vigilar activamente la aparición de neoplasias, así como de osteoporosis y otros trastornos metabólicos, en particular diabetes y enfermedad cardiovascular.

https://doi.org/10.4067/s0034-98872024000600704

What causes obesity in children and adolescents? adolescents
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Nogueira-de-Almeida, Carlos Alberto

; Weffort, Virginia Resende Silva

; Ued, Fábio da V.

; Ferraz, Ivan S.

; Contini, Andrea A.

; Martinez, Edson Zangiacomi

; Ciampo, Luiz A. Del

Jornal de Pediatria

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Abr 2024, Volume 100 Supl. 1 Páginas S48 - S56

Resumo: En | Texto: En | PDF: En

Abstract Objective To present the different aspects that may be involved in the genesis and maintenance of obesity in children and adolescents. Data source Narrative review of articles published in the PubMed, Scielo, Lilacs, Scopus and Google Scholar databases, using the search terms: overweight, obesity, pre-conception, prenatal, infants, schoolchildren, children, and adolescents. The search was conducted in studies written in Portuguese, English and Spanish, including narrative, integrative or systematic reviews, meta-analyses, cross-sectional, case-control and cohort studies, published between 2003 and 2023. Data synthesis A total of 598 studies were initially screened and 60 of them, which showed the main biopsychosocial aspects related to greater risks of excessive adiposity in the pediatric age, were included in the review. The data were presented taking into account the incidence of risk factors and their consequences in six periods: pre-conception, pre-natal, infant, preschool, school age, and adolescence. Conclusions The causal factors described in the scientific literature that have been shown to be related to obesity in childhood and adolescence are presented. adolescents PubMed Scielo Lilacs databases terms overweight preconception, preconception pre conception, conception pre-conception prenatal infants schoolchildren Portuguese Spanish narrative reviews metaanalyses, metaanalyses meta analyses, analyses meta-analyses crosssectional, crosssectional cross sectional, sectional cross-sectional casecontrol case control 200 2023 59 6 them age periods natal, natal pre-natal infant preschool 20 202 5 2

https://doi.org/10.1016/j.jped.2023.09.011

Reducción de la infección por Helicobacter pylori en pacientes derivados a endoscopia digestiva alta en Santiago de Chile entre 2010-2020
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Silva, Felipe

; Latorre, Gonzalo

; Medel, Patricio

; Bustamante, Miguel

; Montero, Isabella

; Robles, Camila

; Dukes, Eitan

; Martinez, Francisca

; Binder, María Victoria

; Uribe, Javier

; Reyes, Diego

; Bittner, Marcela

; Sirhan, Marisol

; Espinoza, Manuel

; Fuentes-López, Eduardo

; Candia, Roberto

; Agüero, Carlos

; Vargas, José Ignacio

; Espino, Alberto

; Riquelme, Arnoldo

Revista de Gastroenterología del Perú

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Jan 2024, Volume 44 Nº 1 Páginas 14 - 20

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN Latinoamérica presenta una alta prevalencia de infección por Helicobacter pylori (Hp). Entre 1996-2003 la prevalencia en Santiago de Chile fue del 70%; estudios recientes presentan una disminución en esta infección. Actualizar la frecuencia de Hp es fundamental debido a su impacto en la salud asociado. Objetivo: Nuestro objetivo fue describir la tendencia de la infección por Hp en pacientes que asisten a endoscopía digestiva alta (EDA) ambulatoria en una población chilena. Materiales y métodos: Se realizó un estudio observacional retrospectivo de pacientes mayores de 18 años que asistieron a una primera EDA con test rápido de ureasa entre 2010-2020. La tendencia en el tiempo fue descrita mediante análisis de series de tiempo. Se construyó un modelo Poisson para estimar el riesgo de infección, ajustado por edad y sexo. Resultados: Se incluyeron 11 355 pacientes [66,9% mujeres; edad media 52 años; Hp 41,6%]. El sexo masculino presentó una mayor frecuencia de infección por Hp [RR 1,13; (IC95%:1,08-1,18)]. La frecuencia de Hp disminuyó significativamente desde 45,1% en 2010 hasta 29% en 2020, con 36% menor probabilidad de presentar infección por Hp en 2020 con respecto al 2010 [RR 0,64; (IC95%:0,55-0,74)]. Se proyectó un descenso progresivo en la tendencia de infección por Hp hasta valores cercanos al 25% para el año 2025. Conclusión: Se observó una reducción significativa en la infección por Hp entre los años 2010-2020. Esta disminución pudiese ser explicada mediante la incorporación de políticas públicas de salud en la última década asociadas a cambios sociosanitarios.

ABSTRACT Latin America presents a high prevalence of Helicobacter pylori (Hp) infection. Between 1996-2003, the prevalence in Santiago, Chile, was 70%; recent studies indicate a decrease in this infection. Updating the frequency of Hp is crucial due to its associated health impact. Objective: Our objective was to describe the trend in Hp infection in patients undergoing ambulatory esophagogastroduodenoscopy (EGD) in a Chilean population. Materials and methods: A retrospective observational study was conducted on patients over 18 years old who attended a first EGD with a rapid urease test between 2010-2020. Time trends were described through time series analysis. A Poisson model was constructed to estimate the risk of infection, adjusted for age and gender. Results: 11,355 patients were included [66.9% females; mean age 52 years; Hp 41.6%]. Male gender presented a higher frequency of Hp infection [RR 1.13; (95% CI: 1.08-1.18)]. Hp frequency infection decreased significantly from 45.1% in 2010 to 29% in 2020, with a 36% lower probability of Hp infection in 2020 compared to 2010 [RR 0.64; (95% CI: 0.55-0.74)]. A progressive decline in Hp infection trend was projected, reaching values close to 25% by year 2025. Conclusion: A significant reduction in Hp infection was observed between 2010-2020. This decrease could be explained by the implementation of public health policies in the last decade associated with socio-sanitary changes.

https://doi.org/10.47892/rgp.2024.441.1624

Efecto cicatrizante en incisiones periodontales por extracto hidroalcohólico de Morinda citrifolia
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Meza, Carlos Samuel Ramos

; Palomo, Erika Eleana Corzo

; Trujillo, Luis Alberto Olivera

; Martinez, Juan Carlos Valencia

; Acuña, Yeni Gutierrez

Vive Revista de Salud

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Ago 2023, Volume 6 Nº 17 Páginas 464 - 481

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Periodontal treatments involve cuts and bleeding of the gingival mucosa; Morinda citrifolia, specifically on the fragments in charge of healing (platelets), has a more significant effect on the healing processes of the lesions. Objective. To identify the healing potential of hydroalcoholic extracts of Morinda citrifolia (Peruvian noni) in the regenerative processes of periodontal incisions at 70% at various concentrations (1%; 5; and 10%) and its accelerating coadjuvant effect in the oral route as tissue healing. Materials and Methods. An applied research was carried out under an experimental design. For this purpose, a previous study was carried out for pharmacognostic analysis, moisture percentage, solubility tests and qualitative phytochemical analysis to ensure that the pharmacological analysis and experimental test were properly completed. Doses were administered to five male Holtzman albino rats divided into four groups to which the concentrations were applied in 0.5 ml amounts twice daily to the incision, which was evaluated for seven days for specific parameters, such as infection, gingival skin tone, wound closure, incision size reduction and percentage healing. Results. They indicated that all groups that were given the 70% hydroalcoholic extract in various concentrations improved their healing activity by reducing the size of the gingival incision on the seventh day, where it turned out that the best concentration was 5% compared to the other concentrations (1% and 10%). Conclusion. Research indicating the efficacy of Peruvian Morinda citrifolia as an accelerator of the healing process in periodontal therapy.

RESUMEN Los tratamientos periodontales implican cortes y sangrado de la mucosa gingival; la Morinda citrifolia, específicamente sobre los fragmentos encargados de la cicatrización (plaquetas), tiene un efecto más significativo en los procesos curativos de las lesiones. Objetivo. Identificar el potencial cicatrizante de los extractos hidroalcohólicos de Morinda citrifolia (noni peruano) en los procesos regenerativos de las incisiones periodontales al 70% a diversas concentraciones (1%; 5; y 10%) y su efecto coadyuvante acelerador en la vía oral como curación de tejidos. Materiales y Métodos. Se realizó una investigación aplicada, bajo el diseño experimental. Para ello, se llevó a cabo un estudio previo para el análisis farmacognóstico, porcentaje de humedad, pruebas de solubilidad y el análisis fitoquímico cualitativo para garantizar que el análisis farmacológico y la prueba experimental se completaran adecuadamente. Se administraron dosis a cinco ratas albinas macho Holtzman divididas en cuatro grupos a los cuales se les aplicó las concentraciones en cantidades de 0,5 ml dos veces al día en la incisión, la cual se evaluó durante siete días para obtener parámetros específicos, como infección, tono de piel gingival, cierre de heridas, reducción del tamaño de la incisión y porcentaje de curación. Resultados. Indicaron que todos los grupos que se le suministró el extracto hidroalcohólico al 70% en varias concentraciones mejoró su actividad curativa al reducir el tamaño de la incisión en la encía al séptimo día, donde resultó que la mejor concentración fue del 5% en comparación con las otras concentraciones (1% y 10%). Investigación que indica la eficacia de la Morinda citrifolia peruana como acelerador del proceso de curación en la terapia periodontal.

RESUMO Os tratamentos periodontais envolvem corte e sangramento da mucosa gengival; a Morinda citrifolia, especificamente sobre os fragmentos responsáveis pela cicatrização (plaquetas), tem um efeito mais significativo nos processos de cicatrização das lesões. Objetivo. Identificar o potencial cicatrizante de extratos hidroalcoólicos de Morinda citrifolia (noni peruano) nos processos regenerativos de incisões periodontais a 70% em diversas concentrações (1%; 5; e 10%) e seu efeito coadjuvante acelerador na via oral como cicatrizante tecidual. Materiais e métodos. Foi realizada uma pesquisa aplicada sob um desenho experimental. Para esse fim, foi realizado um pré-estudo para análise farmacognóstica, porcentagem de umidade, testes de solubilidade e análise fitoquímica qualitativa para garantir que a análise farmacológica e o teste experimental fossem adequadamente concluídos. Cinco ratos albinos Holtzman machos divididos em quatro grupos foram dosados e as concentrações foram aplicadas em quantidades de 0,5 ml duas vezes ao dia na incisão, que foi avaliada por sete dias quanto a parâmetros específicos, como infecção, tônus gengivais da pele, fechamento da ferida, redução do tamanho da incisão e porcentagem de cicatrização. Resultados. Eles indicaram que todos os grupos que receberam extrato hidroalcoólico a 70% em várias concentrações melhoraram sua atividade de cicatrização ao reduzir o tamanho da incisão gengival no sétimo dia, sendo que a melhor concentração foi de 5% em comparação com as outras concentrações (1% e 10%). Conclusão. A pesquisa indica a eficácia da Morinda citrifolia peruana como um acelerador do processo de cicatrização na terapia periodontal.

https://doi.org/10.33996/revistavive.v6i17.238

Análisis de las cirugías cardíacas y mortalidad operatoria en el Instituto Nacional Cardiovascular durante el 2022
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Polo-Gutierrez, Gerber

; Silva-Tejada, Harod Anders

; Martinez-Ninanqui, Franklin Willy

; Robles-Velarde, Victor

; Ríos-Ortega, Josías

Archivos peruanos de cardiología y cirugía cardiovascular

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Abr 2023, Volume 4 Nº 2 Páginas 55 - 61

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN Objetivo . Describir las cirugías cardíacas, su abordaje y determinar la mortalidad operatoria según el tipo de cirugía y las principales complicaciones registradas hasta los 30 días del posoperatorio realizadas en el Instituto Nacional Cardiovascular de Perú. Materiales y métodos. Se llevó a cabo un estudio descriptivo en todos los pacientes mayores de 18 años que fueron sometidos a cirugía cardiovascular en el Instituto Nacional Cardiovascular «Carlos Alberto Peschiera Carrillo». Resultados . Durante el año 2022 se realizaron 503 cirugías cardíacas. De los pacientes intervenidos, el 63,6% (320) fueron varones. La cirugía valvular aislada, principalmente el reemplazo de la válvula aórtica o mitral, fue el procedimiento quirúrgico más frecuente, con 136 cirugías (27,0%). Le siguió la cirugía de revascularización de miocardio con 110 procedimientos (21,9%). A lo largo del año se registraron 23 fallecimientos, lo que resultó en una mortalidad general del 4,5%. La mortalidad en cirugías electivas fue del 2,8%, mientras que en cirugías de emergencia fue del 14,3%. La complicación más común fue la fibrilación auricular paroxística (14,0%), seguida de la infección del sitio quirúrgico con 52 casos (10,3%). Conclusiones . La cirugía valvular, ya sea aislada o en combinación con otros procedimientos, fue realizada con más frecuencia. La tasa de mortalidad obtenida se considera aceptable para un centro de referencia.

ABSTRACT Objective. To describe cardiac surgeries, their approaches, and determine operative mortality according to the type of surgery and the main complications recorded within 30 days postoperatively, performed at the National Cardiovascular Institute of Peru. Materials and methods. A descriptive study was conducted on all patients over 18 years of age who underwent cardiovascular surgery at the National Cardiovascular Institute “Carlos Alberto Peschiera Carrillo”. Results. During the year 2022, a total of 503 cardiac surgeries were performed. Of the patients undergoing surgery, 63.6% (320) were males. Isolated valvular surgery, primarily aortic or mitral valve replacement, was the most frequent surgical procedure, with 136 surgeries (27.0%). This was followed by myocardial revascularization surgery with 110 procedures (21.9%). Throughout the year, there were 23 deaths, resulting in an overall mortality rate of 4.5%. The mortality rate for elective surgeries was 2.8%, while for emergency surgeries, it was 14.3%. The most common complication was paroxysmal atrial fibrillation (14.0%), followed by surgical site infection with 52 cases (10.3%). Conclusions. Valvular surgery, whether isolated or combined with other procedures, was the most frequently performed. The obtained mortality rate is considered acceptable for a reference center.

https://doi.org/10.47487/apcyccv.v4i2.287

El avance de la línea de costa de las penínsulas de Bocagrande y Castillogrande y la construcción de la Escollera en 1758 en Cartagena de Indias
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Andrade-Amaya, Carlos Alberto

; Guzmán-Martinez, Richard

; Quintana-Saavedra, Diana María

Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales

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Set 2022, Volume 46 Nº 180 Páginas 758 - 768

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Se reconstruyeron los paisajes arqueológicos sumergidos frente a la costa de Cartagena de Indias con base en datos batimétricos multihaz de alta resolución provenientes del Servicio Hidrográfico de la Dirección General Marítima de Colombia y la comparación de mapas históricos de 1772, 1854, 1935, 1995 y 2021. Se demuestra que la construcción de la escollera de Bocagrande ha significado la acreción del terreno en este punto en cerca de 44,4 Ha, y que los espolones colocados en la playa en el siglo pasado lo han sostenido.

Abstract The submerged archaeological landscapes off the coast of Cartagena de Indias were reconstructed based on high-resolution multibeam bathymetric data from the Hydrographic Service of the General Maritime Directorate of Colombia and on the comparison of historical maps from 1772, 1854, 1935, 1995, and 2021. We show that the construction of the Bocagrande breakwater has meant the accretion of around 44,4 Ha of land in Bocagrande and the spurs placed on the beach in the last century have sustained it.

https://doi.org/10.18257/raccefyn.1722

Vitamin A deficiency and association between serum retinol and IGF-1 concentrations in Brazilian children with Down syndrome
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Ferraz, Ivan Savioli

; Vieira, Débora Mônica Costa

; Ciampo Jr., Luiz Antonio Del

; Ued, Fábio da Veiga

; Almeida, Ane Cristina Fayão

; Jordão Jr., Alceu Afonso

; Aragon, Davi Casale

; Martinez, Edson Zangiacomi

; Martinelli Jr., Carlos Eduardo

; Nogueira-de-Almeida, Carlos Alberto

Jornal de Pediatria

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Fev 2022, Volume 98 Nº 1 Páginas 76 - 83

Resumo: En | Texto: En | PDF: En

Abstract Objective: To determine the prevalence of vitamin A deficiency (VAD) and serum concentrations of retinol, correlating them with IGF-1 concentrations in preschoolers with DS. Methods: Cross-sectional study was conducted on 47 children with DS aged 24 to 72 months, in Ribeirão Preto, Brazil. VAD was determined by the relative dose-response (RDR) test. Retinol serum concentration ≤ 0.70 μmol/L and IGF-1 serum concentration below the 3rd percentile for sex and age were considered to represent deficiency. C-reactive protein (CRP) was determined at the beginning of the study. Weight, height, and information about fever and/or diarrhea were obtained at the beginning of the study. Results: VAD prevalence was 25.5% (12/47), and 74.5% (35/47) of the children had deficient retinol before the intervention. CRP was not associated with VAD. Mean IGF-1 were 103.5 ng/mL (SD = 913) for the group with VAD and 116.3 ng/mL (SD = 54.9) for the group with no VAD (p-value = 0.85); 8.5% (4/47) of the children showed deficient IGF-1, but without VAD. No association was observed between VAD and IGF-1 deficiency. A moderate positive correlation was observed between pre-intervention retinol and IGF-1 (ρ = 0.37; p-value = 0.01). Conclusion: a high prevalence of VAD and deficient retinol was observed and there was a positive correlation between serum retinol and IGF-1.

https://doi.org/10.1016/j.jped.2021.04.003

The effects of tether pretension within vertebral body tethering on the biomechanics of the spine: a Finite Element analysis
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Nicolini, Luis Fernando

; Greven, Johannes

; Kobbe, Philipp

; Hildebrand, Frank

; Stoffel, Marcus

; Markert, Bernd

; Yllera, Borja Martinez

; Simões, Marcelo Simoni

; Roesler, Carlos Rodrigo de Mello

; Fancello, Eduardo Alberto

Latin American Journal of Solids and Structures

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2022, Volume 19 Nº 3 elocation e442

Resumo: En | Texto: En | PDF: En

Abstract This study investigates the biomechanics of the spine after insertion of vertebral body tethering (VBT) with different cord pretensions. For that purpose, a Finite Element model of the average thoracolumbar spine was stepwise calibrated and validated. The VBT instrumentation was inserted in the left side of the L1-L2 segment with different cord pretensions. As a second test, the L1-L2 segment was submitted to an external pure moment of 6 Nm in left and right lateral bending. The range of motion (ROM) for the spine with VBT was determined with respect to its initial post VBT position. Pretension forces of 100 N and 300 N resulted in a change of scoliotic angle of 2.7° and 5.3° to the left side of the spine, respectively. The ROM of the native spine was 4.5° in right lateral bending and reduced to 1.8° and 1.4° for the cases of the spine with a cord pretension of 100 N and 300 N, respectively. In left lateral bending, the absolute ROM of the native spine was 4.6°. For the cases of a cord pretension of 100 N and 300 N, the spine bent 1.9° and 0.8° to the left side from its initial post VBT position, respectively.

https://doi.org/10.1590/1679-78256932

Volume Measurement System Based on Hall Effect Sensors Circularly Coupled and Arranged in a Quadrature Shape
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Martínez Espinosa, Juan Carlos Ortiz Alvarado, Juan de Dios Córdoba Valdes, Fidel Rodriguez Martinez, Marcos Alberto Fuentes Avila, Marcos Leonardo Guzmán Cabrera, Rafael

Computación y Sistemas

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Jun 2021, Volume 25 Nº 2 Páginas 417 - 422

Resumo: En | Texto: En | PDF: En

Abstract In this research work, a compact electronic system for measuring volumes in generic cylindrical containers was designed and developed. The system is based on a circular arrangement composed of four Hall effect sensors A1324 and arranged in the form of a quadrature. The theoretical volume calculations obtained based on the angle of inclination of the float for a cylindrical container were correlated with a polynomial function of order 3 with an R2 = 0.99. The analog voltage signal correlated with the theoretical volume was digitized through a microcontroller and a ZigBee transceiver was used as a data transmission channel and through a ZigBee Xbee ZB24 transceiver was used for information transfer. The experimental and theoretical results obtained corroborate a highly accurate and reliable measurement system, which can be applied to different containers and different types of fluids that are to be monitored remotely. Finally based on the theoretical model, this system could be scaled to cylindrical containers of greater capacity without modifying the conditions of the electronic system with the array of Hall effect sensors.

https://doi.org/10.13053/cys-25-2-3904

10.

[SciELO Preprints] - Morpho-physiological performance of Mikania glomerata Spreng. and Mikania laevigata Sch. Bip ex Baker plants under different light conditions
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Contin, Daniele Ribeiro Habermann, Eduardo Alves, Vani Maria Martinez, Carlos Alberto

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Data de publicação: 2021-04-12

Resumo: En Pt

In tropical and subtropical zones, lianas play important roles in the process of ecological succession. This study aims to evaluate the photosynthetic and morpho-physiological performance between two lianas species from Mikania genus in response to different levels of radiation: full sun (I0), 25% (I25), 50% (I50), and 75% (I75) retention of solar radiation flux. Plants grown under I75 showed a reduced net photosynthetic rate (A). We observed dynamic photoinhibition at I0 during hours of high irradiation and temperature. The highest and lowest leaf chlorophyll content occurred at I75 and I0, respectively, while carotenoids/total chlorophyll and leaf thickness increased under I0. Total dry mass was higher in plants grown at I0 and I25. However, A values and biomass production of Mikania laevigata were higher at I25, while for Mikania glomerata greater biomass accumulation was observed between I0-I50. Therefore, we concluded that M. laevigata and M. glomerata have different morpho-physiological performances under same the radiation conditions.

Em regiões tropical e subtropical, lianas desempenham um papel importante no processo de sucessão ecológica. O objetivo deste estudo foi avaliar as respostas fotossintéticas e morfo-fisiológicas entre duas espécies de Mikania em diferentes níveis de radiação: sol pleno (I0), 25% (I25), 50% (I50) e 75% (I75) de retenção do fluxo da radiação solar. Plantas crescidas sob I75 mostraram reduzida taxa fotossintética (A). Nós observamos fotoinibição dinâmica em plantas crescidas sob I0 durante as horas de alta irradiação e temperatura. O maior e menor conteúdo de clorofila ocorreu em plantas sob I75 e I0, respectivamente; enquanto carotenoides/clorofila total e espessuras da epiderme e mesofilo aumentaram sob I0. A massa seca total foi maior em plantas crescidas sob I0 e I25. No entanto, os valores de A e a produção de biomassa de M. laevigata foram maiores sob I25; enquanto para M. glomerata, maior acúmulo de biomassa foi observado entre I0-I50. Portanto, nós concluímos que M. laevigata e M. glomerata apresentaram diferentes respostas morfo-fisiológicas sob mesma condição de radiação.

https://doi.org/10.1590/2236-8906-74/2020

11.

Cannabinoids in Neurology - Position paper from Scientific Departments from Brazilian Academy of Neurology
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BRUCKI, Sonia Maria Dozzi

; ADONI, Tarso

; ALMEIDA, Carlos Mauricio Oliveira

; ANDRADE, Daniel Ciampi de

; ANGHINAH, Renato

; BARBOSA, Luciana Mendonça

; BAZAN, Rodrigo

; CARVALHO, Alzira Alves de Siqueira

; CARVALHO, William

; CHRISTO, Paulo Pereira

; COLETTA, Marcus Della

; CONFORTO, Adriana Bastos

; CORREA-NETO, Ylmar

; ENGELHARDT, Eliasz

; FRANÇA JUNIOR, Marcondes Cavalcante

; FRANCO, Clelia

; VON GLEHN, Felipe

; GOMES, Helio Rodrigues

; HOULY, Caroline Gomes de Barros

; KAUP, Alexandre Ottoni

; KOWACS, Fernando

; KANASHIRO, Aline

; LOPES, Victor Gonçalves

; MAIA, Débora

; MANREZA, Maria

; MARTINEZ, Alberto Rolim Muro

; MARTINEZ, Sandra Cristina Gonçalves

; NADER, Saulo Nardy

; NEVES, Luciana de Oliveira

; OKAMOTO, Ivan Hideyo

; OLIVEIRA, Rogério Adas Ayres de

; PEIXOTO, Fabiano de Melo

; PEREIRA, Cristiana Borges

; SABA, Roberta Arb

; SAMPAIO, Leticia Pereira de Brito

; SCHILLING, Lucas Porcello

; SILVA, Marcus Tulius Teixeira

; SILVA, Emanuelle Roberta

; SMID, Jerusa

; SOARES, Cristiane Nascimento

; SOBREIRA-NETO, Manoel

; SOUSA, Nise Alessandra de Carvalho

; SOUZA, Leonardo Cruz de

; TEIVE, Hélio Afonso Ghizoni

; TERRA, Vera Cristina

; VALE, Matheus

; VIEIRA, Vitor Mendes Grise

; ZANOTELI, Edmar

; PRADO, Gilmar

Arquivos de Neuro-Psiquiatria

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Abr 2021, Volume 79 Nº 4 Páginas 354 - 369

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Os canabinoides compreendem os endocanabinoides, fitocanabinoides e os canabinoides sintéticos e desempenham ações no sistema nervoso central e periférico. Uma quantidade enorme de publicações tem sido lançada nos últimos anos, embora a cannabis seja conhecida por milênios. Os Departamentos Científicos da Academia Brasileira de Neurologia descreveram as evidências do uso médico em suas áreas. A literatura está em constantes mudanças e possíveis novas evidências podem surgir nos próximos dias ou meses. A prescrição dessas substâncias deve ser discutida com os pacientes e suas famílias, com conhecimento sobre eventos adversos e sua eficácia.

ABSTRACT Cannabinoids comprehend endocannabinoids, phytocannabinoids, and synthetic cannabinoids, with actions both in the central and peripherical nervous systems. A considerable amount of publications have been made in recent years, although cannabis has been known for over a thousand years. Scientific Departments from the Brazilian Academy of Neurology described evidence for medical use in their areas. Literature is constantly changing, and possible new evidence can emerge in the next days or months. Prescription of these substances must be discussed with patients and their families, with knowledge about adverse events and their efficacy.

https://doi.org/10.1590/0004-282x-anp-2020-0432 1049 downloads

12.

TOXICIDAD DE TRES INSECTICIDAS ORGANOFOSFORADOS EN EMBRIONES DE ANUROS A DIFERENTES TEMPERATURAS
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HENAO MUÑOZ, Liliana Marcela

; TRIANA VELASQUEZ, Teófila María

; GALINDO MARTINEZ, Carlos Alberto

; BERNAL BAUTISTA, Manuel Hernando

Acta Biológica Colombiana

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Abr 2021, Volume 26 Nº 1 Páginas 5 - 11

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN Los efectos de diferentes agroquímicos y de la temperatura han sido temas recurrentes en la investigación en anuros; sin embargo, estas variables se han abordado de manera independiente sin considerar que pueden ejercer una presión simultánea sobre las especies. Por esta razón, este trabajo tiene como objetivo determinar la toxicidad (a través de la Concentración Letal Media -CL50) de los insecticidas organofosforados clorpirifos, diazinón y monocrotofos, bajo tres regímenes térmicos (23, 28 y 33 ± 1 °C) sobre embriones de tres especies de anuros. De acuerdo a los valores de CL50, el insecticida clorpirifos fue el más tóxico, seguido del diazinón y del monocrotofos. Por su parte, de manera general se encontró un incremento de la toxicidad de los insecticidas organofosforados a la temperatura más alta de experimentación (33 °C). Además, el efecto de la temperatura se hizo más notorio para los organismos expuestos al clorpirifos, el insecticida más letal. Estos resultados sugieren un efecto negativo para la fauna acuática de anuros debido al actual uso desmesurado de este tipo de agroquímicos y a su interacción con la temperatura ambiental.

ABSTRACT In anurans, the effects of different agrochemicals and temperature have been recurrent topics in research; however, these variables are addressed independently without considering that they can exert a simultaneous pressure on the species. For this reason, this work aims to determine the toxicity (through the Medium Lethal Concentration -LC50) of the organophosphate insecticides: chlorpyrifos, diazinon and monocrotophos, under three thermal regimes (23, 28 and 33 ± 1 °C) on embryos ofthree species of anurans. According to the LC50 values, the chlorpyrifos insecticide was the most toxic, followed by diazinon and monocrotophos. On the other hand, an increase in the toxicity of the organophosphate insecticides studied was generally found at the highest experimental temperature (33 °C). In addition, the effect of temperature became more noticeable for the organisms exposed to chlorpyrifos, the most lethal insecticide. These results suggest a negative effect for the aquatic fauna of anurans due to the current excessive use of this type of agrochemicals and their interaction with environmental temperature.

https://doi.org/10.15446/abc.v26n1.78618

13.

The Pterygospinous Foramen (Civinini) and the Pterygoalar (Crotaphitico-Buccinatorius). Laboratory Findings
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Oliveira, Kennedy Martinez de de-Almeida, Valério Landim López, Carlos Alberto Carranza Brandão, Guilherme Tatagiba Trancoso, Marcos Guilherme Bedim Oliveira, Maísa de Fátima Satiro Morais, Isabela Coimbra Ladeira Soares, Daniele Cristina Barbosa Costa, Luana Carolina Maletta

International Journal of Morphology

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Fev 2021, Volume 39 Nº 1 Páginas 198 - 204

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

SUMMARY: The Pterygospinous foramen and pterygoalar foramen (crotaphitico-buccinatorius) are variant and atavic formations of the skull base and arise respectively from complete or incomplete idiopathic ossifications of the pterygospinous and pterygoalar ligaments. By proximity with areas of relevance for diagnosis and surgery, such as access pathways to the parapharyngeal and retropharyngeal spaces, it is necessary to be aware of these conditions due to the difficulties generated in surgical maneuvers and the promotion of compressive syndromes of mandibular nerve branches. This study was conducted on 45 samples of dry skulls and disarticulated sphenoid bones belonging to the collection of the Federal University of Juiz de Fora, Governador Valadares campus, Minas Gerais, Brazil. Our results indicated a total incidence of complete and incomplete pterygospinous and pterygoalar foramen (crotaphitico- buccinatorius) in 15, 5 % (7 skulls), with a higher incidence for the incomplete form of pterygospinous foramen (Civinini foramen) in 4 skulls (8.8 %), with 3 presenting unilaterally and 3 presenting bilaterally. The pterygoalar foramen (crotaphitico-buccinatorius or Hyrtl) was noted bilaterally in 1 of the skulls (2.2 %). The pterygospinous foramen and pterygoalar foramen are important findings, sometimes incidental, of an area of great anatomical expressiveness and pathological occurrences, besides the indispensable and unclear studies of phylogenetic order.

RESUMEN: El foramen pterigoespinoso y el foramen pterigoalar (crotafítico-buccinatorius) son formaciones variantes y atávicas de la base del cráneo y surgen respectivamente de osificaciones idiopáticas completas o incompletas, de los ligamentos pterigoespinoso y pterigoalar. Debido a la proximidad con áreas de relevancia para el diagnóstico y la cirugía, como las vías de acceso a los espacios parafaríngeo y retrofaríngeo, es necesario conocer estas condiciones por las dificultades que se generan en las maniobras quirúrgicas. Este estudio se realizó en 45 muestras de cráneos secos y huesos esfenoides desarticulados pertenecientes a la colección de la Universidad Federal de Juiz de Fora, campus Governador Valadares, Minas Gerais, Brasil. Nuestros resultados indicaron una incidencia total de foramen pterigoespinoso y pterigoalar completo e incompleto (crotafítico-buccinatorius) en el 15,5 % (7 cráneos), con una mayor incidencia de la forma incompleta de foramen pterigoespinoso (agujero de Civinini) en 4 cráneos (8,8 %), con 3 de presentación unilateral y 3 de presentación bilateral. El foramen pterigoalar (crotaphitico-buccinatorius o Hyrtl) se observó bilateralmente en 1 de los cráneos (2,2 %). El foramen pterigoespinoso y pterigoalar son hallazgos importantes, a veces incidentales, de un área de gran expresividad anatómica y ocurrencias patológicas, además de los estudios indispensables y poco claros de orden filogenético.

14.

The Program for Biodiversity Research in Brazil: The role of regional networks for biodiversity knowledge, dissemination, and conservation
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ROSA, CLARISSA

; BACCARO, FABRICIO

; CRONEMBERGER, CECILIA

; HIPÓLITO, JULIANA

; BARROS, CLAUDIA FRANCA

; RODRIGUES, DOMINGOS DE JESUS

; NECKEL-OLIVEIRA, SELVINO

; OVERBECK, GERHARD E.

; DRECHSLER-SANTOS, ELISANDRO RICARDO

; ANJOS, MARCELO RODRIGUES DOS

; FERREGUETTI, ÁTILLA C.

; AKAMA, ALBERTO

; MARTINS, MARLÚCIA BONIFÁCIO

; TOMAS, WALFRIDO MORAES

; SANTOS, SANDRA APARECIDA

; FERREIRA, VANDA LÚCIA

; CUNHA, CATIA NUNES DA

; PENHA, JERRY

; PINHO, JOÃO BATISTA DE

; SALIS, SUZANA MARIA

; DORIA, CAROLINA RODRIGUES DA COSTA

; PILLAR, VALÉRIO D.

; PODGAISKI, LUCIANA R.

; MENIN, MARCELO

; BÍGIO, NARCÍSIO COSTA

; ARAGÓN, SUSAN

; MANZATTO, ANGELO GILBERTO

; VÉLEZ-MARTIN, EDUARDO

; SILVA, ANA CAROLINA BORGES LINS E

; IZZO, THIAGO JUNQUEIRA

; MORTATI, AMANDA FREDERICO

; GIACOMIN, LEANDRO LACERDA

; ALMEIDA, THAÍS ELIAS

; ANDRÉ, THIAGO

; SILVEIRA, MARIA AUREA PINHEIRO DE ALMEIDA

; SILVEIRA, ANTÔNIO LAFFAYETE PIRES DA

; MESSIAS, MARILUCE REZENDE

; MARQUES, MARCIA C.M.

; PADIAL, ANDRE ANDRIAN

; MARQUES, RENATO

; BITAR, YOUSZEF O.C.

; SILVEIRA, MARCOS

; MORATO, ELDER FERREIRA

; PAGOTTO, RUBIANI DE CÁSSIA

; STRUSSMANN, CHRISTINE

; MACHADO, RICARDO BOMFIM

; AGUIAR, LUDMILLA MOURA DE SOUZA

; FERNANDES, GERALDO WILSON

; OKI, YUMI

; NOVAIS, SAMUEL

; FERREIRA, GUILHERME BRAGA

; BARBOSA, FLÁVIA RODRIGUES

; OCHOA, ANA C.

; MANGIONE, ANTONIO M.

; GATICA, AILIN

; CARRIZO, MARÍA CELINA

; RETTA, LUCÍA MARTINEZ

; JOFRÉ, LAURA E.

; CASTILLO, LUCIANA L.

; NEME, ANDREA M.

; RUEDA, CARLA

; TOLEDO, JOSÉ JULIO DE

; GRELLE, CARLOS EDUARDO VIVEIROS

; VALE, MARIANA M.

; VIEIRA, MARCUS VINICIUS

; CERQUEIRA, RUI

; HIGASHIKAWA, EMÍLIO MANABU

; MENDONÇA, FERNANDO PEREIRA DE

; GUERREIRO, QUÊZIA LEANDRO DE MOURA

; BANHOS, AUREO

; HERO, JEAN-MARC

; KOBLITZ, RODRIGO

; COLLEVATTI, ROSANE GARCIA

; SILVEIRA, LUÍS FÁBIO

; VASCONCELOS, HERALDO L.

; VIEIRA, CECÍLIA RODRIGUES

; COLLI, GUARINO RINALDI

; CECHIN, SONIA ZANINI

; SANTOS, TIAGO GOMES DOS

; FONTANA, CARLA S.

; JARENKOW, JOÃO A.

; MALABARBA, LUIZ R.

; RUEDA, MARTA P.

; ARAUJO, PUBLIO A.

; PALOMO, LUCAS

; ITURRE, MARTA C.

; BERGALLO, HELENA GODOY

; MAGNUSSON, WILLIAM E.

Anais da Academia Brasileira de Ciências

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2021, Volume 93 Nº 2 elocation e20201604

Resumo: En | Texto: En | PDF: En

Abstract The Program for Biodiversity Research (PPBio) is an innovative program designed to integrate all biodiversity research stakeholders. Operating since 2004, it has installed long-term ecological research sites throughout Brazil and its logic has been applied in some other southern-hemisphere countries. The program supports all aspects of research necessary to understand biodiversity and the processes that affect it. There are presently 161 sampling sites (see some of them at Supplementary Appendix), most of which use a standardized methodology that allows comparisons across biomes and through time. To date, there are about 1200 publications associated with PPBio that cover topics ranging from natural history to genetics and species distributions. Most of the field data and metadata are available through PPBio web sites or DataONE. Metadata is available for researchers that intend to explore the different faces of Brazilian biodiversity spatio-temporal variation, as well as for managers intending to improve conservation strategies. The Program also fostered, directly and indirectly, local technical capacity building, and supported the training of hundreds of undergraduate and graduate students. The main challenge is maintaining the long-term funding necessary to understand biodiversity patterns and processes under pressure from global environmental changes.

https://doi.org/10.1590/0001-3765202120201604 1034 downloads

15.

BRAZILIAN GASTRIC CANCER ASSOCIATION GUIDELINES (PART 2): UPDATE ON TREATMENT
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BARCHI, Leandro Cardoso

; RAMOS, Marcus Fernando Kodama Pertille

; DIAS, André Roncon

; FORONES, Nora Manoukian

; CARVALHO, Marineide Prudêncio de

; CASTRO, Osvaldo Antonio Prado

; KASSAB, Paulo

; COSTA-JÚNIOR, Wilson Luiz da

; WESTON, Antônio Carlos

; ZILBERSTEIN, Bruno

; Ferraz, Álvaro Antônio Bandeira ZeideCharruf, Amir Brandalise, André Silva, André Maciel da Alves, Barlon Marins, Carlos Augusto Martinez Malheiros, Carlos Alberto Leite, Celso Vieira Bresciani, Claudio José Caldas Szor, Daniel Mucerino, Donato Roberto Wohnrath, Durval R. JirjossIlias, Elias Martins Filho, Euclides Dias PinatelLopasso, Fabio Coimbra, Felipe José Fernandez Felippe, Fernando E. Cruz Tomasisch, Flávio Daniel Saavedra Takeda, Flavio Roberto Ishak, Geraldo Laporte, Gustavo Andreazza Silva, Herbeth José Toledo Cecconello, Ivan Rodrigues, Joaquim José Gama Grande, José Carlos Del Lourenço, Laércio Gomes Motta, Leonardo Milhomem da Ferraz, Leonardo Rocha Moreira, Luis Fernando Lopes, Luis Roberto Toneto, Marcelo Garcia Mester, Marcelo Rodrigues, Marco Antônio Gonçalves Franciss, Maurice Youssef AdamiAndreollo, Nelson Corletta, Oly Campos Yagi, Osmar Kenji Malafaia, Osvaldo Assumpção, Paulo Pimentel Savassi-Rocha, Paulo Roberto Colleoni Neto, Ramiro Oliveira, Rodrigo Jose de AissarSallun, Rubens Antonio Weschenfelder, Rui Oliveira, Saint Clair Vieira de Abreu, Thiago Boechat de Castria, Tiago Biachi de Ribeiro Junior, Ulysses Barra, Williams Freitas Júnior, Wilson Rodrigues de

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

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2021, Volume 34 Nº 1 elocation e1563

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Racional: O II Consenso Brasileiro de Câncer Gástrico da Associação Brasileira de Câncer Gástrico ABCG (Parte 1) foi recentemente publicado. Nesta ocasião inúmeros especialistas que atuam no tratamento desta doença expressaram suas opiniões diante declarações apresentadas. Objetivo: Apresentar as Diretrizes da ABCG (Parte 2) quanto às indicações de tratamento cirúrgico, técnicas operatórias, extensão de ressecção e terapia combinada. Métodos: Para formulação destas diretrizes os autores realizaram extensa e atual revisão referente a cada declaração presente no II Consenso, utilizando as bases Medline/PubMed, Cochrane Library e SciELO, inicialmente com os seguintes descritores: câncer gástrico, gastrectomia, linfadenectomia, terapia combinada. Ainda, cada declaração foi classificada de acordo com o nível de evidência e grau de recomendação. Resultados: Das 43 declarações presentes neste estudo, 11 (25,6%) foram classificadas com nível de evidência A, 20 (46,5%) B e 12 (27,9%) C. Quanto ao grau de recomendação, 18 (41,9%) declarações obtiveram grau de recomendação 1, 14 (32,6%) 2a, 10 (23,3%) 2b e um (2,3%) 3. Conclusão: O complemento das diretrizes aqui presentes possibilita que cirurgiões e oncologistas que atuam no combate ao câncer gástrico possam oferecer o melhor tratamento possível, de acordo com as condições locais disponíveis.

ABSTRACT Background : The II Brazilian Consensus on Gastric Cancer of the Brazilian Gastric Cancer Association BGCA (Part 1) was recently published. On this occasion, countless specialists working in the treatment of this disease expressed their opinion in the face of the statements presented. Aim : To present the BGCA Guidelines (Part 2) regarding indications for surgical treatment, operative techniques, extension of resection and multimodal treatment. Methods: To formulate these guidelines, the authors carried out an extensive and current review regarding each declaration present in the II Consensus, using the Medline/PubMed, Cochrane Library and SciELO databases initially with the following descriptors: gastric cancer, gastrectomy, lymphadenectomy, multimodal treatment. In addition, each statement was classified according to the level of evidence and degree of recommendation. Results : Of the 43 statements present in this study, 11 (25,6%) were classified with level of evidence A, 20 (46,5%) B and 12 (27,9%) C. Regarding the degree of recommendation, 18 (41,9%) statements obtained grade of recommendation 1, 14 (32,6%) 2a, 10 (23,3%) 2b e one (2,3%) 3. Conclusion : The guidelines complement of the guidelines presented here allows surgeons and oncologists who work to combat gastric cancer to offer the best possible treatment, according to the local conditions available.

https://doi.org/10.1590/0102-672020210001e1563 768 downloads

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Você pode enriquecer sua busca de uma forma muito simples. Use os índices de pesquisa combinados com os conectores (AND ou OR) e especifique cada vez mais sua busca.

Por exemplo, se você deseja buscar artigos sobre
casos de dengue no Brasil em 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

Veja abaixo a lista completa de índices de pesquisa que podem ser usados:

Cód. do Índice	Elemento
ti	título do artigo
au	autor
kw	palavras-chave do artigo
subject	assunto (palavras do título, resumo e palavras-chave)
ab	resumo
ta	título abreviado da revista (ex. Cad. Saúde Pública)
journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

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Email: scielo@scielo.org

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