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CLINICAL AND RADIOLOGICAL PARAMETERS IN MALIGNANT SPINAL TUMORS: A DESCRIPTIVE ANALYSIS
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Menezes, Marcelo Diniz de

; Pontes, Mariana Demétrio de Sousa

; Herrero, Carlos Fernando Pereira da Silva

Acta Ortopédica Brasileira

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2025, Volume 33 Nº 1 elocation e285913

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: Descrever os parâmetros clínicos, radiológicos dos tumores malignos da coluna vertebral. Métodos: Esse é um estudo terapêutico do tipo estudo retrospectivo descritivo. A avaliação clínica incluiu idade, sexo, lesões tumorais, tratamentos e procedimentos cirúrgicos, além das complicações. A avaliação radiológica analisou exames radiográficos, tomografias computadorizadas e ressonâncias; focando em características morfopatológicas e os tratamentos empregados. Resultados: Entre os 236 pacientes avaliados, a maioria era do sexo feminino, com idades entre 6 e 91 anos. A principal queixa reportada foi a lombalgia. A abordagem cirúrgica mais utilizada foi a via de acesso posterior, incluindo fixação pelicular e descompressão do canal vertebral. A complicação mais prevalente observada foi a infecção. A maioria dos pacientes apresentava tumores primários de mama. O segmento mais frequentemente acometido da coluna vertebral foi o torácico. Ao analisar as porções da coluna vertebral afetadas, observou-se que a porção do arco posterior foi a mais comumente comprometida. Conclusão: A apresentação clínica e radiológica dos pacientes com lesões metastáticas na coluna vertebral em nossa amostra foi semelhante aos relatos da literatura. Resultados cirúrgicos alinharam-se às expectativas prévias. Nota-se a presença de sintomas iniciais, com variação nos intervalos entre sintomas, diagnóstico e tratamento. Nível de Evidência III; Estudo Retrospectivo Comparativo.

Abstract Objective: To describe the clinical and radiological parameters of spine malignant tumors. Methods: This is a therapeutic study of the descriptive retrospective type. Clinical evaluation included age, sex, tumor lesions, treatments, surgical procedures, and complications. The radiological evaluation analyzed radiographic exams, computed tomographies, and MRIs, focusing on morpho-pathological characteristics and the treatments employed. Results: Among the 236 patients evaluated, the majority were female, aged 6 to 91 years. The main complaint reported was low back pain. The most commonly used surgical approach was the posterior access, including pedicle fixation and decompression of the spinal canal. The most prevalent complication observed was infection. The majority of patients had primary breast tumors. The predominantly affected segment of the spine was the thoracic. Upon analyzing the portions of the spine affected, it was observed that the posterior arch portion was the most commonly affected. Conclusion: The clinical and radiological presentation of patients with metastatic lesions in the spine in our sample was similar to reports in the literature. Surgical outcomes aligned with previous expectations. Initial symptoms were noted, varying intervals between symptoms, diagnosis, and treatment. Level of Evidence III; Comparative Retrospective Study.

https://doi.org/10.1590/1413-785220253301e285913

Joint statement on evidence-based practices in mechanical ventilation: suggestions from two Brazilian medical societies
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Ferreira, Juliana Carvalho

; Vianna, Arthur Oswaldo de Abreu

; Pinheiro, Bruno Valle

; Maia, Israel Silva

; Baldisserotto, Sérgio Vasconcellos

; Isola, Alexandre Marini

; Cavalcanti, Alexandre Biasi Gama, Ana Maria Casati Nogueira da Rocha, Angelo Roncalli Miranda Oliveira, Antonio Gonçalves de Serpa Neto, Ary Farias, Augusto Manoel de Carvalho Orlando, Bianca Rodrigues Esteves, Bruno da Costa Mazza, Bruno Franco Silveira, Camila de Freitas Martins Soares Carvalho, Carlos Roberto Ribeiro de Toufen Junior, Carlos Barbas, Carmen Silvia Valente Teixeira, Cassiano Silveira, Débora Dutra da Medeiros, Denise Machado Parolo, Edino Costa, Eduardo Leite Vieira Caser, Eliana Bernadete Oliveira, Ellen Pierre de Banholzer, Eric Grieger Carvalho, Erich Vidal Amorim, Fabio Ferreira Saddy, Felipe Gonçalves, Fernanda Alves Ferreira Galas, Filomena Regina Barbosa Gomes Zanatta, Giovanna Carolina Gardini Silva, Gisele Sampaio Westphal, Glauco Adrieno Matos, Gustavo Faissol Janot de Souza, João Claudio Emmerich de Silva Junior, João Manoel Valiatti, Jorge Luis dos Santos Nascimento Junior, José Ribamar do Rocco, Jose Rodolfo Hajjar, Ludhmila Abrahão Forgiarini Junior, Luiz Alberto Malbuisson, Luiz Marcelo Sá Holanda, Marcelo Alcantara Amato, Marcelo Britto Passos Park, Marcelo Oliveira, Marco Antonio da Rosa e Reis, Marco Antonio Soares Tavares, Marcos Soares Souza, Mario Henrique Dutra de Damasceno, Marta Cristina Pauleti Lira-Batista, Marta Maria da Silva Pattacini, Max Morais Assunção, Murillo Santucci Cesar de Oliveira, Neymar Elias de Franzosi, Oellen Stuani Rocco, Patricia Rieken Macedo Caruso, Pedro Silva, Pedro Leme Mendes, Pedro Vitale Duarte, Pericles Almeida Delfino Santa Neto, Renato Fabio Alberto Della Rodrigues, Ricardo Goulart Cordioli, Ricardo Luiz Palazzo, Roberta Fittipaldi Goldwasser, Rosane Pinheiro, Sabrina dos Santos Justino, Sandra Regina Nemer, Sergio Nogueira Oliveira, Vanessa Martins de Silva, Vinicius Zacarias Maldaner da Nedel, Wagner Luis Bellissimo-Rodrigues, Wanessa Teixeira Oliveira Filho, Wilson de

Critical Care Science

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2025, Volume 37 elocation e20250242en

Resumo: En | Texto: En | PDF: En

ABSTRACT Mechanical ventilation can be a life-saving intervention, but its implementation requires a multidisciplinary approach, with an understanding of its indications and contraindications due to the potential for complications. The management of mechanical ventilation should be part of the curricula during clinical training; however, trainees and practicing professionals frequently report low confidence in managing mechanical ventilation, often seeking additional sources of knowledge. Review articles, consensus statements and clinical practice guidelines have become important sources of guidance in mechanical ventilation, and although clinical practice guidelines offer rigorously developed recommendations, they take a long time to develop and can address only a limited number of clinical questions. The Associação de Medicina Intensiva Brasileira and the Sociedade Brasileira de Pneumologia e Tisiologia sponsored the development of a joint statement addressing all aspects of mechanical ventilation, which was divided into 38 topics. Seventy-five experts from all regions of Brazil worked in pairs to perform scoping reviews, searching for publications on their specific topic of mechanical ventilation in the last 20 years in the highest impact factor journals in the areas of intensive care, pulmonology, and anesthesiology. Each pair produced suggestions and considerations on their topics, which were presented to the entire group in a plenary session for modification when necessary and approval. The result was a comprehensive document encompassing all aspects of mechanical ventilation to provide guidance at the bedside. In this article, we report the methodology used to produce the document and highlight the most important suggestions and considerations of the document, which has been made available to the public in Portuguese.

https://doi.org/10.62675/2965-2774.20250242-en

DEVELOPMENT OF A GRAVITATIONAL AND PENDULUM SOLAR TRACKER FOR STANDALONE PHOTOVOLTAIC PANELS
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Wissmann, Jorge A.

; Nogueira, Carlos E. C. Zampiva, Marcelo M. M. Siqueira, Jair A. C. Bassegio, Doglas

Engenharia Agrícola

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2025, Volume 45 elocation e20230186

Resumo: En | Texto: En | PDF: En

ABSTRACT The contribution of photovoltaic energy has steadily increased within the energy matrix worldwide. Within this renewable energy system, optimization is there is continually pursued, which can be achieved through various approaches, including advancements in photovoltaic cell technology, impedance adjustments, inverter efficiency, collected energy storage (either on- or off-grid), cell cooling, module cleaning, and solar position tracking, which was the focus of this study. In remote areas without electrical grid access, motorized systems may not be feasible. A tracking prototype was developed whose structure is classified as chronological due to its fixed rotation, manual as it requires daily adjustment, single-axis azimuthal, and "analog" as it lacks motors, sensors, or algorithms. The results showed that the developed tracking prototype achieved a 9.69% energy production increase during the research period, with peaks of 35.51% on sunny days, and a significant efficiency improvement during the early morning and late afternoon. Statistical analysis results revealed a significant energy production difference between panels. In terms of economy, the prototype proved unviable when compared to the cost of grid electricity.

https://doi.org/10.1590/1809-4430-eng.agric.v45e20230186/2025

From hope to reality: How telehealth and strategic procurement are reshaping public health
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da Silva Jr., Jarbas Barbosa García Saisó, Sebastián Cornejo, Santiago Rodriguez, Daniel Fitzgerald, James Marti, Myrna Balleste, Jordi Itman, Isaac Otero, Carlos Báscolo, Ernesto D’Agostino, Marcelo

Revista Panamericana de Salud Pública

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2025, Volume 49 elocation e28

Resumo: En | Texto: En | PDF: En

https://doi.org/10.26633/rpsp.2025.28

Rápida propagación del genotipo emergente cosmopolita del virus dengue serotipo 2, y expansión del genotipo V de dengue serotipo 1 en el Perú
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Bailon, Henri

; Jimenez, Víctor

; Galarza, Marco

; Medrano, Princesa

; Mestanza, Orson

; Figueroa, Dana

; Lizarraga, Wendy

; Silva, Iris

; Sevilla, Luren

; Hurtado, Verónica

; Izarra, Vanessa

; Padilla, Carlos

; Barcena, Luis

; Caceres, Omar

; Merino, Susy

; Marcelo, Adolfo

; Ruiz, Nora

; Hapuarachchii, Hapuarachchige Chanditha

; Sánchez, César Cabezas

; García, María P.

Revista Peruana de Medicina Experimental y Salud Pública

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Dez 2024, Volume 41 Nº 4 Páginas 375 - 384

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN Objetivos . En el presente estudio se evaluó la prevalencia y distribución del genotipo V del virus del dengue serotipo 1 (DENV-1) y del genotipo cosmopolita serotipo 2 (DENV-2) en Perú entre los años 2019 y 2022. Materiales y métodos. La región del gen de la envoltura (E) se amplificó a partir de 79 muestras de suero mediante reacción en cadena de la polimerasa (PCR) y se secuenció mediante tecnología de secuenciación de nueva generación (NGS). Las secuencias obtenidas se analizaron posteriormente mediante herramientas bioinformáticas. Resultados. El estudio generó secuencias del gen de la envoltura de los serotipos DENV-1 y DENV-2. Nuestro estudio reveló una rápida dispersión y amplia distribución del genotipo cosmopolita DENV-2 en diversas regiones del Perú en 2022, así como la propagación del genotipo V DENV-1 a nuevas regiones peruanas, junto con el genotipo cosmopolita DENV-2. Conclusiones. Nuestros hallazgos sugieren la urgente necesidad de fortalecer los sistemas de vigilancia epidemiológica y genómica para conocer y controlar la expansión de los genotipos circulantes del DENV en Perú. Esto permitirá una respuesta más rápida, a la vez que el monitoreo de su potencial diseminación a otros países de las Américas.

ABSTRACT Objectives. This study aimed to evaluate the prevalence and distribution of dengue virus genotype V serotype 1 (DENV-1) and cosmopolitan genotype serotype 2 (DENV-2) in Peru between 2019 and 2022. Materials and methods. The envelope (E) gene region was amplified from 79 serum samples by polymerase chain reaction (PCR) and sequenced by next-generation sequencing (NGS) technology. The obtained sequences were subsequently analyzed with bioinformatics tools. Results. The study generated envelope gene sequences of DENV-1 and DENV-2 serotypes. Our study revealed a rapid dispersal and wide distribution of the cosmopolitan DENV-2 genotype in several regions of Peru in 2022, as well as the spread of DENV-1 genotype V to new Peruvian regions, along with the cosmopolitan DENV-2 genotype. Conclusions. Our findings suggest the urgent need to strengthen epidemiological and genomic surveillance systems to understand and control the spread of circulating DENV genotypes in Peru. This will allow a more rapid response, as well as the monitoring of its potential dissemination to other countries in the Americas.

https://doi.org/10.17843/rpmesp.2024.414.13898

ÁRBOLES Y SOCIEDAD: PERCEPCIONES SOBRE JUGLANS NEOTROPICA DIELS
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Sono Toledo, Daniel David

; Carvajal Benavides, José Gabriel

; Arcos Unigarro, Carlos Ramiro

; Albuja Illescas, Luis Marcelo

; Aroca Farez, Adriana Elizabeth

Perfiles

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Dez 2024, Volume 1 Nº 32 Páginas 55 - 62

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT The development of humanity maintains a close relationship with the surrounding biodiversity, from which it obtains goods and services. The study of social perceptions about the importance of a species is necessary to be able to know, disseminate and contribute to the conservation of species. Juglans neotropica Diels, native to the Andes, has traditionally been used in various ways; to document them, a survey based on the Likert scale was carried out in the parishes of San Antonio de Ibarra and San Francisco de Natabuela, province of Imbabura. For the analysis, frequency tables, descriptive statistics and correlation analysis were carried out between the numerical values of the survey. It was determined that the main uses of the species are timber, the most relevant being carving (72,72%), followed by cabinetmaking (53,59%) and furniture (52,49%). Of the thirteen proposed uses, an average relevance of 3,01 was obtained, equivalent to not very relevant; while for carving the average was 3,97 classified as relevant. In the correlation analysis, it was recorded that 32,05% of the relationships presented p-values <0,0001, that is, highly significant correlations. It was determined that Juglans neotropica has multiple uses and is considered of relevant importance in Imbabura.

RESUMEN El desarrollo de la humanidad mantiene una estrecha relación con la biodiversidad circundante, de donde obtiene bienes y servicios. El estudio de las percepciones sociales sobre la importancia de una especie es necesario para poder conocer, difundir y contribuir a la conservación de especies. Juglans neotropica Diels, nativa de los Andes, ha sido tradicionalmente empleada de diversas maneras, para documentarlas se realizó una encuesta basada en la escala Likert en las parroquias San Antonio de Ibarra y San Francisco de Natabuela, provincia de Imbabura. Para el análisis se realizaron tablas de frecuencias, estadística descriptiva y análisis de correlación entre los valores numéricos de la encuesta. Se determinó que los principales usos que tiene la especie son los maderables, siendo el más relevante el tallado (72,72%), seguido por ebanistería (53,59%) y muebles (52,49%). De los trece usos propuestos, se obtuvo una relevancia promedio de 3,01, equivalente a poco relevante; mientras que para el tallado la media fue de 3,97 clasificado como relevante. En el análisis de correlación se registraron que el 32,05% de las relaciones presentaron p-valores <0,0001, es decir correlaciones altamente significativas. Se determinó que Juglans neotropica presenta múltiples usos y es considerada de importancia relevante en Imbabura.

https://doi.org/10.47187/perf.v1i32.299

Translation into Portuguese (Brazil), cultural adaptation and validation of Parathyroid Assessment of Symptoms (PAS) in patients with chronic kidney disease and hyperparathyroidism
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Campos, Rafael Costa e

; Amaral, Rayssa Ruszkowski do

; Hentschke, Marta Ribeiro

; Toneto, Marcelo Garcia

; Poli-de-Figueiredo, Carlos Eduardo

Brazilian Journal of Nephrology

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Dez 2024, Volume 46 Nº 4 elocation e20220059

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Introduction: Chronic kidney disease (CKD) is related to high morbidity and mortality and loss of quality of life. Likewise, hyperparathyroidism is associated to progressive loss of renal function, with increased phosphate and decrease calcium levels, which induce the secretion of parathyroid hormone. Objectives: To translate into Portuguese (Brazil), culturally adapt and validate the questionnaire Parathyroid Symptoms Assessment (PAS), following reliability and validity criteria in patients with chronic kidney disease and hyperparathyroidism. Methods: Methodological and cross-sectional study, carried out at São Lucas Hospital/PUCRS, Porto Alegre, Brazil. The PAS questionnaire validation process followed protocols from previous studies. After translating into Portuguese, it was applied to 100 patients with secondary (SHPT) and tertiary or persistent (THPT) hyperparathyroidism. For PAS validation data, patients responded to the Short Form Health 36 (SF-36) questionnaire. Reliability criteria were evaluated using intraclass correlation coefficient (ICC) and Cronbach’s alpha (α-C). Validity was assessed by Spearman’s correlation coefficient between PAS and SF-36 values. Results: Participant’s mean age was 55.6 ± 15.6 years, 61% was male, and 68% was diagnosed with SHPT. Among 100 patients, 53% performed a PAS retest (ICC = 0.83). The internal reliability by α-C was 0.86. Negative correlations were observed between PAS questions and SF-36 physical and mental domains, which ranged from 0.3 to 0.7. Conclusion: The Brazilian version of the PAS questionnaire was found to be valid and reliable. The PAS questionnaire can be used to evaluate quality of life in Brazilian patients with hyperparathyroidism who speak Portuguese.

Resumo Introdução: A doença renal crônica (DRC) está relacionada à elevada morbimortalidade e perda de qualidade de vida. Igualmente, o hiperparatireoidismo está associado à perda progressiva da função renal, com níveis aumentados de fosfato e diminuição de cálcio, que induzem secreção do paratormônio. Objetivos: Traduzir para língua portuguesa (Brasil), adaptar culturalmente e validar o questionário Parathyroid Symptoms Assessment (PAS), seguindo critérios de confiabilidade e validade em pacientes com DRC e hiperparatireoidismo. Métodos: Estudo metodológico e transversal, realizado no Hospital São Lucas/PUCRS, Porto Alegre, Brasil. O processo de validação do questionário PAS seguiu protocolos de estudos anteriores. Após tradução para o português, aplicou-se a 100 pacientes com hiperparatireoidismo secundário (HPTS) e terciário ou persistente (HPTT). Para dados de validação do PAS, os pacientes responderam ao questionário Short Form Health 36 (SF-36). Critérios de confiabilidade foram avaliados usando coeficiente de correlação intraclasse (CCI) e alfa de Cronbach (α-C). A validade foi avaliada pelo coeficiente de correlação de Spearman entre valores de PAS e SF-36. Resultados: A idade média dos participantes foi 55,6 ± 15,6 anos, 61% eram homens e 68% foram diagnosticados com HPTS. Entre 100 pacientes, 53% realizaram reteste de PAS (CCI = 0,83). A confiabilidade interna por α-C foi 0,86. Observaram-se correlações negativas entre questões do PAS e os domínios físico e mental do SF-36, que variaram de 0,3 a 0,7. Conclusão A versão brasileira do questionário PAS mostrou-se válida e confiável. O questionário PAS pode ser usado para avaliar qualidade de vida em pacientes brasileiros com hiperparatireoidismo que falam português.

https://doi.org/10.1590/2175-8239-jbn-2022-0059en

Rápida propagación del genotipo emergente cosmopolita del virus dengue serotipo 2, y expansión del genotipo V de dengue serotipo 1 en el Perú
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Bailon, Henri

; Jimenez, Víctor

; Galarza, Marco

; Medrano, Princesa

; Mestanza, Orson

; Figueroa, Dana

; Lizarraga, Wendy

; Silva, Iris

; Sevilla, Luren

; Hurtado, Verónica

; Izarra, Vanessa

; Padilla, Carlos

; Barcena, Luis

; Caceres, Omar

; Merino, Susy

; Marcelo, Adolfo

; Ruiz, Nora

; Chanditha Hapuarachchii, Hapuarachchige

; Cabezas Sánchez, César

; García, María P.

Revista Peruana de Medicina Experimental y Salud Publica

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Out 2024, Volume 41 Nº 4 Páginas 375 - 384

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

https://doi.org/10.17843/rpmesp.2024.414.13898

Alkalized lidocaine in endotracheal tube cuff inflation in patients undergoing thyroidectomy surgery: a clinical trial
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Barbosa Junior, Gaudencio

; Granja Filho, Geraldo José Coelho

; Oliveira, Caio Marcio Barros de

; Leal, Plínio da Cunha

; Andrade, Marcelo Souza de

; Moura, Ed Carlos Rey

Revista da Associação Médica Brasileira

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Out 2024, Volume 70 Nº 10 elocation e20240740

Resumo: En | Texto: En | PDF: En

SUMMARY OBJECTIVE: The aim of the study was to compare the postoperative effects of endotracheal tube cuff inflation with alkalized lidocaine in patients undergoing thyroidectomy surgery. METHODS: This is a randomized, double-blind clinical trial between August 2020 and August 2022 at the Hospital São Domingos, São Luís, Maranhão, Brazil. Patients over 18 years who underwent thyroidectomy of both sexes, American Society of Anesthesiologists (ASA) I or ASA II, were included. Patients with difficult orotracheal intubation, smoking, cuff rupture during orotracheal intubation, heart, lung, or neuropathies, previous surgery of the larynx or trachea, with risk of aspiration of gastric contents, or with the need to use a nasogastric tube were excluded. Patients were randomly selected and divided into the control group, whose cuff was filled with 0.9% saline solution, and the alkalinized lidocaine group, where the cuff was filled with 2% lidocaine and 8.4% sodium bicarbonate. RESULTS: The control group had higher systolic blood pressure [137 (94–183) mmHg] medians after extubation than the alkalinized lidocaine group [127 (82–189) mmHg] (p=0.03). The same was observed in heart rate values [control group: 86 (62–120); alkalinized lidocaine group: 80 (53–120)] (p=0.034). The alkalinized lidocaine group showed a significant increase in the ability to sustain phonation in the 24 h postoperatively, from 82.0 to 98.0% (p=0.031). CONCLUSION: There was no protective effect of the use of alkalinized lidocaine on the sensation of swallowing and complaints after thyroidectomy surgery. There was a significant improvement in hemodynamic response in the intervention group after extubation.

https://doi.org/10.1590/1806-9282.20240740

10.

¿Cómo llega el paciente asmático al servicio de emergencias? Datos del estudio multicéntrico SABINA EMERGENCIAS
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Sivori, Martín Pascansky, Daniel Pascansky, Martín Saldarini, Fernando Brichetti, Valeria Csipka, Paula Franchi, Eugenia Videla, Alejandro Rodríguez, Marcelo Laborde, Luciana Orazi, María Laura Benito, Flemón Oliva, Carlos Blua, Ariel

Respirar

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Set 2024, Volume 16 Nº 3 Páginas 3 - 3

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Introducción: Los objetivos del control del asma son prevenir la aparición de síntomas y reducir el riesgo de exacerbaciones y mortalidad mediante educación médica, técnica inhalatoria, adherencia a medicación controladora e indicación de planes de acción (PA); pero los pacientes enfrentan exacerbaciones de diversa gravedad. Objetivos: El objetivo principal del estudio SABINA EMERGENCIAS fue describir la forma en que los pacientes concurren al servicio de emergencias (SE), considerando la frecuencia y uso de medicación de rescate. Objetivos secundarios: consultas al SE; uso de corticoides sistémicos (CS), agonistas beta-2 de acción corta (SABA) y tratamiento controlador; disponibilidad de PA. Material y Métodos: Estudio transversal, observacional, descriptivo, en cuatro hospitales del área metropolitana de Buenos Aires en adultos con asma. Resultados: n=323 (edad: 43,7±16,8 años; mujeres: 66,6%): 61,3% no eran seguidos por especialistas; 90,1% utilizaron SABA como rescate (mediana:10 inhalaciones; rango 0-100) la semana previa; 75,9% tuvieron >1 consulta al SE el año previo (mediana:2 [0-100]); 29,4% habían sido hospitalizados; 59,1% recibieron >1 ciclo de CS; mediana de consumo de SABA: 3 envases/año (0-23); 51,7% habían utilizado >3 envases; 30% no empleaban tratamiento de mantenimiento (23% usaba SABA); 75,9% no efectuaban terapia regular de mantenimiento; 77,1% no contaban con PA. Conclusión: Una reducida proporción de pacientes asmáticos que concurren al SE son seguidos por médicos especialistas, con alto consumo y elevada frecuencia de aplicación de SABA como rescate y baja adherencia al tratamiento de mantenimiento. Se remarca la necesidad de optimizar el manejo, con énfasis en la derivación al especialista, adherencia al tratamiento y prescripción de PA.

Abstract Introduction: The objectives of asthma control are to prevent the onset of symptoms and reduce the risk of exacerbations and mortality through medical education, inhaler technique, adherence to controller medication and indication of action plans (AP); but patients experience exacerbations of varying severity. Objective: The main objective of the SABINA EMERGENCIAS study was to describe how patients attend the emergency department (ED), considering the frequency and use of rescue medication. Secondary objectives: ED visits; use of systemic corticosteroids (SC), short-acting beta-2 agonists (SABA) and controller therapy; availability of AP. Methods: Cross-sectional, observational, descriptive study in 4 hospitals in the metro-politan area of Buenos Aires in adults with asthma. Results: n=323 (age:43.7±16.8 years; women:66.6%): 61.3% were not followed by spe-cialists; 90.1% used SABA as rescue medication (median:10 puffs; range 0-100) the previous week; 75.9% had >1 visit to the ES the previous year (median: 2 [0-100]); 29.4% had been hospitalized; 59.1% received >1 cycle of CS; median SABA consump-tion: 3 cannisters/year (0-23); 51.7% had used >3 cannisters; 30% did not use mainte-nance therapy (23% used SABA); 75.9% did not perform regular maintenance therapy; 77.1% did not have an AP. Conclusion: A small proportion of asthmatic patients attending the ES are followed by specialist physicians, with high consumption and high frequency of SABA application as rescue medication and low adherence to maintenance treatment. The need to opti-mize management is highlighted, with emphasis on referral to specialists, adherence to treatment and prescription of APs.

https://doi.org/10.55720/respirar.16.3.3

11.

Innovation, technologies and barriers in the tourism sector in the north of Caldas, Colombia
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Pantoja, Martín A.

; López, Marcelo

; Marulanda, Carlos E.

Ingeniería y competitividad

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Ago 2024, Volume 26 Nº 2 elocation e-21113695

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen El objetivo del artículo es presentar los resultados generales del sector turístico del norte del Departamento de Caldas y específicamente un análisis relacionado con la innovación, el uso de las tecnologías de información y las barreras que se viene presentando en dicho sector, partiendo de una investigación cualitativa, con un tipo de estudio descriptivo y correlacional, se utilizó un análisis multivariado y se logró consolidar una base de respuesta de 68 empresarios directos e indirectos del sector turístico de los municipios de Neira y Salamina del Departamento de Caldas. Los resultados presentan que, para las empresas encuestadas, la innovación en turismo es fundamental para el crecimiento de ellas y la creación de experiencias innovadoras, así como es de importante el uso de las redes sociales como las herramientas más efectivas de difusión de nuevos productos turísticos. Se concluye que la ausencia de respaldo gubernamental impacta negativamente en el crecimiento económico tanto de los operadores turísticos como de las empresas del sector.

Abstract The objective of this article is to present the general results of the tourism sector in the northern part of the Department of Caldas and specifically an analysis related to innovation, the use of information technologies and the barriers that are being presented in this sector. Based on a qualitative research, with a descriptive and correlational type of study a multivariate analysis was used and it was possible to consolidate a response base of 68 direct entrepreneurs direct and indirect businessmen of the tourism sector in the municipalities of Neira and Salamina in the Department of Caldas. The results show that, for the companies surveyed, innovation in tourism is fundamental for their growth. and the creation of innovative experiences, as well as the use of social networks as the most effective tools for disseminating new tourism products. It is concluded that the absence of governmental support has a negative impact on the economic growth of both tour operators and companies in the sector.

https://doi.org/10.25100/iyc.v26i2.13695

12.

Determinantes sociales, equidad y pertinencia territorial: reflexión sobre el enfoque en salud
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Herrera-Vásquez, Luis Carlos

; Núñez-Norambuena, Marcelo Eduardo

Revista Científica de la UCSA

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Ago 2024, Volume 11 Nº 2 Páginas 78 - 88

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Social determinants of health are non-medical factors that have a significant impact on the health of populations. These determinants, ranging from socioeconomic conditions to the physical and social environment, influence access to health care and health outcomes. In this academic text, the theory of social determinants of health, furthermore, the importance of the concept of health equity is highlighted, differentiating it from equality, and the reflection on the positive transition from a biomedical paradigm to one with a holistic approach. Finally, the need to carry out studies of territorial relevance to promote better health in local communities is argued.

RESUMEN Los determinantes sociales de la salud son factores no médicos que tiene un impacto significativo en la salud de las poblaciones. Estos determinantes, que abarcan desde condiciones socioeconómicas hasta el entorno físico y social, influyen en el acceso a la atención médica y en los resultados de salud. En este texto académico, se explora la teoría de los determinantes sociales de la salud, además, se subraya la importancia del concepto de equidad en salud, diferenciándolo de la igualdad, y la reflexión sobre el positivo tránsito de un paradigma biomédico a uno de enfoque holístico. Finalmente, se argumenta la necesidad de realizar estudios de pertinencia territorial para promover una mejor salud en las comunidades locales.

https://doi.org/10.18004/ucsa/2409-8752/2024.011.02.078

13.

Thyroid cancer in patients undergoing thyroidectomy total in the Otorhinolaryngology Department of the Hospital de Clínicas during the period 2018-2022
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Serrano, Ricardo

; Canata, Carlos Mena

; Maidana, Raúl Tornaco

; Villalba, Marcelo

Medicina clínica y social

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Ago 2024, Volume 8 Nº 2 Páginas 153 - 157

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: Thyroid cancer, considered one of the most frequent malignant tumors of the endocrine system, accounts for 80%-90% of cases. The most common histological type observed in most studies is papillary cancer. Objective: To determine the frequency of thyroid cancer in patients undergoing total thyroidectomy at the Otorhinolaryngology Department of the Hospital de Clínicas between the period 2018-2022. Methodology: This retrospective study included 260 patients treated during the study period. Data were obtained from the patients' medical records, and sociodemographic and clinical variables related to thyroid cancer were analyzed. Data were analyzed with the SPSS v25 program, using descriptive statistics. Results: The frequency of thyroid cancer was 48.1%. The mean age of the cancer patients was 42.10±13.10 years. A higher frequency was observed in females 34.2%, n=89) and among those aged 25-44 years 20.0%, n=52). The most frequent were papillary (36.9%), follicular (2.7%), medullary (1.5%), and anaplastic (1.2%) types. Discussion: The frequency of thyroid cancer is high; it is more common in women and as age increases.

RESUMEN Introducción: El cáncer de tiroides, considerado uno de los tumores malignos más frecuentes del sistema endocrino, representa entre el 80% y el 90% de los casos. El tipo histológico más común observado en la mayoría de los estudios es el cáncer papilar. Objetivo: Determinar la frecuencia de cáncer de tiroides en pacientes sometidos a tiroidectomía total en la Cátedra y Servicio de Otorrinolaringología del Hospital de Clínicas durante el período 2018-2022. Metodología: se realizó un estudio retrospectivo con un total de 260 pacientes atendidos en el período de estudio. Los datos fueron tomados de las historias clínicas de los pacientes, en el cual se analizan variables sociodemográficas y clínicas relacionadas con el cáncer de tiroides. Los datos se analizaron con el programa SPSS v25, mediante estadística descriptiva. Resultados: La frecuencia del cáncer de tiroides fue del 48.1%. El promedio de edad de los pacientes con cáncer fue de 42.10±13.10 años. se observó una mayor frecuencia en las personas del sexo femenino 34.2% (n=89) y entre quienes tuvieron de 25-44 años 20.0% (n=52). El más frecuente fue el tipo papilar 36.9%, el folicular 2.7%, el medular 1.5% y el anaplásico 1.2%. Discusión: la frecuencia de cáncer de tiroides es alta, es más frecuente en las mujeres y a medida que aumenta la edad.

https://doi.org/10.52379/mcs.v8i2.398

14.

Clinical outcomes prediction in kidney transplantation by use of biomarkers from hypothermic machine perfusion
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Leite, Ricardo Ribas de Almeida

; Leite Jr, Maurilo Einicker-Lamas, Marcelo Valverde, Rafael Hospodar Felippe Miranda, Luiz Carlos Duarte Schanaider, Alberto

International braz j urol

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Ago 2024, Volume 50 Nº 4 Páginas 470 - 479

Resumo: En | Texto: En | PDF: En

ABSTRACT Purpose The clinical outcomes of kidney transplantation from deceased donors have seen significant improvements with the use of machine perfusion (MP), now a standard practice in transplant centers. However, the use of perfusate biomarkers for assessing organ quality remains a subject of debate. Despite this, some centers incorporate them into their decision-making process for donor kidney acceptance. Recent studies have indicated that lactate dehydrogenase (LDH), glutathione S-transferase, interleukin-18, and neutrophil gelatinase-associated lipocalin (NGAL) could predict post-transplant outcomes. Materials and Methods Between August 2016 and June 2017, 31 deceased-donor after brain death were included and stroke was the main cause of death. Pediatric patients, hypersensitized recipients were excluded. 43 kidneys were subjected to machine perfusion. Perfusate samples were collected just before the transplantation and stored at -80ºC. Kidney transplant recipients have an average age of 52 years, 34,9% female, with a BMI 24,6±3,7. We employed receiver operating characteristic analysis to investigate associations between these perfusate biomarkers and two key clinical outcomes: delayed graft function and primary non-function. Results The incidence of delayed graft function was 23.3% and primary non-function was 14%. A strong association was found between NGAL concentration and DGF (AUC=0.766, 95% CI, P=0.012), and between LDH concentration and PNF (AUC=0.84, 95% CI, P=0.027). Other perfusate biomarkers did not show significant correlations with these clinical outcomes. Conclusion The concentrations of NGAL and LDH during machine perfusion could assist transplant physicians in improving the allocation of donated organs and making challenging decisions regarding organ discarding. Further, larger-scale studies are required.

https://doi.org/10.1590/s1677-5538.ibju.2024.0166

15.

Validación de la prueba estandarizada eureka: evaluación de aprendizaje y dificultades específicas de aprendizaje en lenguaje y matemática
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Miranda Carvajal, Carlos

; Cárdenas Sepúlveda, Marcelo

; Muñoz Zolotoochin, Mariana

; Vergara Rojas, Felipe

Revista enfoques educacionales

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Jun 2024, Volume 21 Nº 1 Páginas 165 - 183

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo: O objetivo da seguinte pesquisa é relatar os resultados da aplicação massiva do teste Eureka para alcançar sua padronização no Chile. Este teste permite-nos ter um instrumento psicopedagógico para o diagnóstico precoce de Dificuldades Específicas de Aprendizagem (DET) considerando, por um lado, o currículo nacional chileno e, por outro, as competências cognitivas necessárias para alcançar níveis de aprendizagem bem sucedidos. Neste contexto, foi realizada uma análise quantitativa da aplicação dos 2.138 desempenhos da prova de linguagem e dos 2.254 desempenhos da prova de matemática a alunos do primeiro ao oitavo ano. No cenário atual, detecta-se a falta de uma avaliação contextualizada para os estudantes chilenos e mesmo em nível latino-americano. Os resultados da pesquisa mostram que o teste Eureka é um instrumento que permite diagnosticar DEA em alunos do primeiro ao oitavo ano e ajuda a estabelecer estratégias de intervenção que melhorem a prática docente direcionada de forma personalizada de acordo com os resultados obtidos.

Abstract: The aim of the following research is to report the results of the widespread application of the Eureka test to achieve its standardization in Chile. This test offers a psychopedagogical tool for the early diagnosis of specific learning difficulties (SLD), considering, on one hand, the Chilean national curriculum, and on the other, the cognitive skills necessary to achieve successful learning outcomes. Within this framework, a quantitative analysis was conducted on 2138 language test renditions and 2254 math test renditions given to students from 1st to 8th grade. In the current scenario, there is a noticeable absence of a contextualized assessment for Chilean students, and even at the Latin American level. The research results show that the Eureka test is an instrument that can diagnose SLD in students from first to eighth grade and assists in establishing intervention strategies that enhance teaching practices, tailored according to the results obtained.

Resumen: El objetivo de la siguiente investigación es dar cuenta de los resultados de la aplicación masiva de la prueba Eureka para lograr su estandarización en Chile. Esta prueba permite contar con un instrumento psicopedagógico para el diagnóstico temprano de Dificultades Específicas del Aprendizaje (DEA) considerando, por un lado, el currículum nacional chileno y por otro, las habilidades cognitivas necesarias para alcanzar niveles de aprendizaje exitosos. En este marco, se realizó un análisis cuantitativo de la aplicación de las 2138 rendiciones de la prueba de lenguaje y a 2254 rendiciones de la prueba de matemáticas a estudiantes desde primero hasta octavo básico. En el escenario actual se detecta la carencia de una evaluación contextualizada para los estudiantes chilenos e incluso a nivel latinoamericano. Los resultados de la investigación arrojan que la prueba Eureka es un instrumento que permite diagnosticar DEA en estudiantes de primero a octavo básico y ayuda a establecer estrategias de intervención que mejoran la práctica docente dirigidas de manera personalizada de acuerdo con los resultados obtenidos.

https://doi.org/10.5354/2735-7279.2024.75121

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