Abstract Pyogenic granuloma is a benign lesion of the skin or mucosa that frequently occurs in the head and neck region. The description of this lesion in the auricle or other regions of the external ear is very rare, with 7 cases published in the literature in the last 20 years. Treatment consists of surgical excision of the lesion. We present the case of a 20-year-old woman who presented with a friable lesion of the auricle, in the region of the cymba concha. It was excised under local anesthesia. One week after excision of the lesion, she had a small scab at the excision site. Six months after excision of the lesion, it showed no signs of recurrence or visible aesthetic defects.

Resumo O granuloma piogénico é uma lesão benigna da pele ou da mucosa que ocorre frequentemente na região da cabeça e pescoço. A descrição desta lesão no pavilhão auricular ou noutras regiões do ouvido externo é muito rara, com 7 casos publicados na literatura nos últimos 20 anos. O tratamento consiste na excisão cirúrgica da lesão. Apresentamos o caso de uma jovem de 20 anos que se apresenta com uma lesão friável do pavilhão auricular, na região da cymba concha. Foi efetuada a excisão da mesma, sob anestesia local. Uma semana após a excisão da lesão, apresentava uma pequena crosta no local da excisão. Seis meses após a excisão da lesão, não apresentava sinais de recidiva ou defeitos estéticos visíveis.

Abstract Primary ciliary dyskinesia (PCD) is a rare genetic disease characterized by an abnormality in the function or structure of the cilia, coursing with pulmonary, otological and nasosinusal manifestations. Hypoacusis affects 60% of patients with PCD and results mainly from otitis media with effusion (OME) and otological complications such as simple or cholesteatomatous chronic otitis media (COM). Clinical case: Female patient, 52 years old, with PCD, followed in the Otorhinolaryngology department for bilateral COM and chronic rhinosinusitis. Her surgical history includes nasosinusal endoscopic surgery and repeated myringotomies with placement of transtympanic ventilation tubes (TVTT), bilaterally. Despite the placement of TVTT, the simple tone audiogram revealed bilateral severe chronic mixed deafness, with mean bone thresholds of 36.25 dB on the right and 30 dB on the left. Ear tomography excluded erosion or discontinuity of ossicular chains, presence of cholesteatoma and pathology of the inner ear. The patient underwent surgery to place a bone conduction implant in her right ear. After 4 weeks, the processor was activated. The free field audiogram revealed a mean threshold of 26.25dB. Conclusion: In PCD patients, insertion of TVTT is still a controversial treatment for OME. Persistent postoperative otorrhea is a frequent side effect and may complicate the use and tolerance of hearing aids. Bone conduction implants should be considered in auditory rehabilitation, with excellent results.

Resumo A discinésia ciliar primária (DCP) é uma doença genética rara caracterizada por uma anormalidade da função ou da estrutura dos cílios, cursando com manifestações pulmonares, otológicas e nasossinusais. A hipoacusia afeta 60% dos pacientes com DCP e resulta sobretudo de otite média com efusão (OME) e de complicações otológicas, como otite média crónica (OMC) simples ou colesteatomatosa. Caso clínico: Doente do sexo feminino, 52 anos, portadora de DCP, seguida na consulta de Otorrinolaringologia por OMC bilateral e rinossinusite crónica. Tem como antecedentes cirúrgicos, cirurgia endoscópica nasossinusal e repetidas miringotomias com colocação de tubos de ventilação transtimpânicos (TVTT), bilateralmente. Apesar da colocação de TVTT, o audiograma tonal simples revelava uma surdez mista severa crónica bilateralmente, com limiares ósseos médios de 36,25 dB à direita e de 30 dB à esquerda. A tomografia computorizada dos ouvidos excluiu erosão ou descontinuidade das cadeias ossiculares, presença de colesteatoma e patologia do ouvido interno. A doente foi submetida a cirurgia para colocação de implante de condução óssea no ouvido direito. Após 4 semanas da cirurgia, foi feita a ativação do processador. O audiograma tonal simples, em campo livre, revelou um limiar aéreo médio de 26,25dB. Conclusão: Nos doentes com DCP, a inserção de TVTT é ainda um tratamento controverso da OME. A otorreia pós-operatória persistente é um efeito colateral frequente, podendo complicar o uso e tolerância dos aparelhos auditivos. Por este motivo deverão ser considerados os implantes de condução óssea na reabilitação auditiva, apresentando excelentes resultados.

SUMMARY OBJECTIVE: The aim of this study was to compare the obstetric and perinatal complications in women who became pregnant with autologous oocytes and those who received donated oocytes (DO) in intracytoplasmic sperm injection cycles (ICSI). METHODS: A retrospective cohort study was carried out by collecting data from medical records between 2019 and 2022. Only patients who underwent ICSI in an induced cycle using their own or freshly DO, with male infertility factor and tubal factor, were included. RESULTS: A total of 120 patients were assessed, comprising 51 cases utilizing their own oocytes (control group) and 69 cases employing DO (study group). Patients receiving DO (n=69) exhibited a significantly higher mean age compared to those utilizing their own oocytes (n=51) (41.96±2.16 vs 38.54±1.42 years, p<0.001). There was no significant association between the source of oocytes and gestational age at delivery (p=0.296), birth weight (p=0.836), admission to neonatal intensive care unit (ICU) (p=0.120), or maternal admission to adult ICU (p=0.767). Additionally, the origin of oocytes did not demonstrate any significant association with the risk of pre-eclampsia (p=0.357), gestational diabetes mellitus (p=0.187), premature rupture of membranes (p=0.996), uterine atony (p=0.996), placenta previa (p=0.393), oligohydramnios (p=0.393), or gestational hypertension (p=0.393)." CONCLUSION: An increase in obstetric and perinatal complications was not observed in pregnancies with DO compared to pregnancies with autologous oocytes in women undergoing ICSI without prior comorbidities. Further studies with larger sample sizes are required to validate our findings. OBJECTIVE (DO ICSI. . (ICSI) METHODS 201 2022 included RESULTS 12 assessed 5 control group 6 group. n=69 n69 n (n=69 n=51 n51 (n=51 41.96±2.16 4196216 41 96 2 16 (41.96±2.1 3854142 38 54 1 42 38.54±1.4 years p<0.001. p0001 p p<0.001 0 001 p<0.001) p=0.296, p0296 p=0.296 , 296 (p=0.296) p=0.836, p0836 p=0.836 836 (p=0.836) (ICU p=0.120, p0120 p=0.120 (p=0.120) p=0.767. p0767 p=0.767 767 (p=0.767) Additionally preeclampsia pre eclampsia p=0.357, p0357 p=0.357 357 (p=0.357) p=0.187, p0187 p=0.187 187 (p=0.187) p=0.996, p0996 p=0.996 996 (p=0.996) p=0.393, p0393 p=0.393 393 (p=0.393) p=0.393. (p=0.393). CONCLUSION comorbidities findings (ICSI 20 202 n=6 n6 (n=6 n=5 n5 (n=5 41.96±2.1 419621 4 9 (41.96±2. 385414 3 38.54±1. p000 p<0.00 00 p029 p=0.29 29 (p=0.296 p083 p=0.83 83 (p=0.836 p012 p=0.12 (p=0.120 p076 p=0.76 76 (p=0.767 p035 p=0.35 35 (p=0.357 p018 p=0.18 18 (p=0.187 p099 p=0.99 99 (p=0.996 p039 p=0.39 39 (p=0.393 n= (n= 41.96±2. 41962 (41.96±2 38541 38.54±1 p00 p<0.0 p02 p=0.2 (p=0.29 p08 p=0.8 8 (p=0.83 p01 p=0.1 (p=0.12 p07 p=0.7 7 (p=0.76 p03 p=0.3 (p=0.35 (p=0.18 p09 p=0.9 (p=0.99 (p=0.39 (n 41.96±2 4196 (41.96± 3854 38.54± p0 p<0. p=0. (p=0.2 (p=0.8 (p=0.1 (p=0.7 (p=0.3 (p=0.9 41.96± 419 (41.96 385 38.54 p<0 p=0 (p=0. 41.96 (41.9 38.5 p< p= (p=0 41.9 (41. 38. (p= 41. (41 (p (4 (

Abstract Fulminant necrotizing eosinophilic myocarditis (FNEM) is a rare form of EM characterized by biventricular heart failure with hemodynamic deterioration, often requiring inotropes or mechanical circulatory support. Here, we report a case of a 43-year-old healthy woman with FNEM who was admitted with acute heart failure that rapidly progressed to cardiogenic shock and electrical storm, culminating in cardiac arrest. Early diagnosis and prompt administration of corticosteroids in combination with veno-arterial extracorporeal membrane oxygenation allowed complete recovery of biventricular systolic function. (FNEM deterioration support Here 43yearold yearold 43 year old storm arrest venoarterial veno arterial function 4

RESUMO Atualmente, muitos sistemas de abastecimento de água coletam e monitoram dados diariamente, com destaque para valores de níveis de reservatórios, pressões e demandas de consumo, além de dados elétricos. Os dados gerados são transformados em informações, proporcionando o conhecimento necessário para direcionar o gestor no planejamento de ações e tomadas de decisão em geral. R é uma linguagem de programação muito utilizada para análises estatísticas e recentemente alguns trabalhos apresentaram o uso do software R acoplado ao EPANET. Dessa forma, este trabalho objetivou avaliar a potencialidade do programa R interligado ao EPANET para banco de dados de sistemas de abastecimento de água. Nesse intuito, considerou-se a metodologia em propor uma simulação no R de uma rede de distribuição de água teórica criada no EPANET para avaliar os resultados da demanda de consumo diário. A rede proposta foi simulada variando-se demandas de consumo com os níveis do reservatório, sendo obtidos vários resultados no período de 24 horas. Consequentemente, foi possível automatizar o processo de análises estatísticas gerando tabelas, gráficos referentes à dispersão das demandas, pressões dos nós, vazões dos trechos oriundos de cada variação de consumo e níveis de reservatório. Os resultados obtidos comprovaram a compatibilidade e a praticidade do modelo matemático de distribuição de água projetada no programa EPANET simulada no R e armazenada no banco de dados SQL server. Atualmente diariamente reservatórios elétricos informações geral forma intuito considerouse considerou se diário variandose variando reservatório 2 horas Consequentemente tabelas nós server

ABSTRACT Currently, many water supply systems collect and monitor data daily, among which we can highlight values of reservoir levels, pressures, and consumption demands, in addition to electrical data. The data generated is transformed into information, providing the necessary knowledge to guide the manager in planning actions and making decisions in general. The R program is a programming language widely used for statistical analysis and, recently, in some R works coupled to EPANET. Thus, this work aimed to evaluate the potential of the R program interconnected to EPANET for the database of water supply systems. For this purpose, the methodology of proposing a simulation in R of a theoretical water distribution network created in EPANET was considered to evaluate the results of daily consumption demand. The proposed network was simulated by varying consumption demands with reservoir levels, obtaining several results in 24 hours. Consequently, it was possible to automate the process of statistical analysis, generating tables and graphs referring to the dispersion of demands, node pressures, and outflows of the stretches arising from each variation in consumption and reservoir levels. The results obtained proved the compatibility and practicality of the mathematical model of the water distribution project in the EPANET program, simulated in R and stored in the SQL SERVER database. Currently levels pressures information general recently Thus purpose demand 2 hours Consequently

RESUMO O objetivo deste trabalho foi avaliar a caracterização físico-química e adsortiva do rejeito de Fe coletado no distrito de Brumadinho; e verificar seu efeito na germinação de Raphanus sativus. O material foi coletado na camada superficial (0–20 cm) e desintegrado para determinação de pH, potencial redox (Eh), condutividade elétrica (EC), matéria orgânica (MO), capacidade de troca catiônica (CEC), área superficial específica (SSA) e de grupos funcionais. Estudos de adsorção foram conduzidos utilizando azul de metileno (MB). Os resultados dos estudos de adsorção foram analisados utilizando modelos cinéticos (Elovich, pseudoprimeira ordem – PFO e pseudossegunda ordem – PSO) e modelos isotérmicos (Freundlich, Langmuir e Sips). O rejeito apresenta pH ácido (5,60), ΔpH negativo (-0,30) e baixa CEC (1,85 cmolc g-1). Foi verificada alta eficiência de adsorção de MB (96%). O modelo de Elovich (0,9248 < R2 < 0,9858) representou melhor a cinética química e o modelo de Freundlich descreveu melhor o processo de adsorção de MB no rejeito (R2 = 0,9609). A capacidade máxima de adsorção (qm) foi igual a 15,08 mg g-1. A presença de rejeito de Fe influenciou positivamente a germinação de sementes de R. sativus (73,8%), mas o crescimento do caule e da raiz foi inferior quando comparado às mudas cultivadas em substrato composto. Conclui-se que o material tem capacidade de adsorção catiônica favorável, o que pode beneficiar a fertilização do solo. No entanto, o desenvolvimento de R. sativus foi menor no substrato de rejeito de Fe, provavelmente devido à baixa CTC, MO e disponibilidade de nutrientes. físicoquímica físico Brumadinho 0–20 020 0 20 (0–2 cm Eh, Eh , (Eh) EC, EC (EC) MO, (MO) CEC, (CEC) SSA (SSA funcionais MB. . (MB) Elovich, (Elovich PSO Freundlich, (Freundlich Sips. Sips Sips) 5,60, 560 5,60 5 60 (5,60) 0,30 030 30 (-0,30 1,85 185 1 85 (1,8 g1. g1 g g-1) 96%. 96 96% (96%) 0,9248 09248 9248 (0,924 R 0,9858 09858 9858 (R 0,9609. 09609 0,9609 9609 0,9609) qm (qm 1508 15 08 15,0 1. g-1 73,8%, 738 73,8% 73 8 (73,8%) composto Concluise Conclui se favorável solo entanto CTC nutrientes 0–2 02 2 (0– (Eh (EC (MO (CEC (MB 56 5,6 6 (5,60 0,3 03 3 (-0,3 1,8 18 (1, 9 (96% 0,924 0924 924 (0,92 0,985 0985 985 0960 0,960 960 150 15, g- 73,8 7 (73,8% 0– (0 5, (5,6 0, (-0, 1, (1 (96 0,92 092 92 (0,9 0,98 098 98 096 0,96 73, (73,8 ( (5, (-0 (9 0,9 09 (0, (73, (5 (- (73 (7

ABSTRACT The objective of this work was to evaluate the physicochemical and adsorptive characterization of Fe tailing collected in the district of Brumadinho; and verify its effect on Raphanus sativus germination. The material was collected on the surface layer (0-20 cm) and disintegrated for pH, redox potential – Eh, electrical conductivity – EC, OM, cation exchange capacity – CEC, specific surface area – SSA and functional groups characterization. Adsorption studies were conducted using methylene blue (MB). The results of the adsorption studies were analyzed using kinetic models (Elovich, pseudo-first order – PFO and pseudo-second order – PSO) and isotherm models (Freundlich, Langmuir and Sips). The tailing has an acidic pH (5.60), negative ΔpH (-0.30) and low CEC (1.85 cmolc g-1). A high MB adsorption efficiency (96%) was verified. The Elovich model (0.9248<R2<0.9858) best represented the chemical kinetics, and the Freundlich model best describes the MB adsorption process in the tailing (R2 = 0.9609). The maximum adsorption capacity (qm) was equal to 15.08 mg g-1. The presence of Fe tailing positively influenced the germination of R. sativus seeds (73.8%), but stem and root growth were inferior when compared to seedlings cultivated in compost substrate. It is concluded that the material has favorable cationic adsorption capacity, which can benefit soil fertilization. However, R. sativus development was minor in Fe tailing substrate, probably due to low CEC, OM and nutrient availability. Brumadinho 020 0 20 (0-2 cm Eh EC MB. . (MB) Elovich, (Elovich pseudofirst pseudo first pseudosecond second PSO Freundlich, (Freundlich Sips. Sips Sips) 5.60, 560 5.60 , 5 60 (5.60) 0.30 030 30 (-0.30 1.85 185 1 85 (1.8 g1. g1 g g-1) 96% 96 (96% verified 0.9248<R2<0.9858 09248R209858 R 9248 R2 9858 (0.9248<R2<0.9858 kinetics (R 0.9609. 09609 0.9609 9609 0.9609) qm (qm 1508 15 08 15.0 1. g-1 73.8%, 738 73.8% 73 8 (73.8%) substrate fertilization However availability 02 2 (0- (MB 56 5.6 6 (5.60 0.3 03 3 (-0.3 1.8 18 (1. 9 (96 0.9248<R2<0.985 09248R20985 924 985 (0.9248<R2<0.985 0960 0.960 960 150 15. g- 73.8 7 (73.8% (0 5. (5.6 0. (-0. (1 (9 0.9248<R2<0.98 09248R2098 92 98 (0.9248<R2<0.98 096 0.96 73. (73.8 ( (5. (-0 0.9248<R2<0.9 09248R209 (0.9248<R2<0.9 09 0.9 (73. (5 (- 0.9248<R2<0. 09248R20 (0.9248<R2<0. (73 0.9248<R2<0 09248R2 (0.9248<R2<0 (7 0.9248<R2< 09248R (0.9248<R2< 0.9248<R2 (0.9248<R2 0.9248<R (0.9248<R

Abstract Evaluate the shaping ability and preparation time using a pediatric motor-driven rotary instrumentation compared to other systems in resin prototypes of primary molars. Methods: Thirty specimens were scanned in micro-CT and divided into three groups according to the instrumentation type: pediatric motor-driven Sequence baby File (SBF); conventional motor-driven (Sequence Rotary File - SRF); manual K file. Instrumentation time was timed. After preparation, the specimens were scanned again. The pre- and post-instrumentation images were superimposed to measure the amount of root canal deviation and the resin remnant thickness. ANOVA followed by the Tukey test analyzed the comparisons between groups (p<0.05). Results: No statistically significant differences occurred in root canal deviation among groups (p>0.05). There were statistically significant differences in the comparison among root thirds (p<0.001) but without significant differences in the interaction group vs. root third (p>0.05). Both motor-driven instrumentations showed statistically greater weariness than manual instrumentation (p<0.001), without significant significant differences between SBF and SRF. Motor-driven instrumentation had a shorter working time than manual instrumentation (p<0.001). Conclusion: Pediatric motor-driven instrumentation demonstrated good outcomes in relation to root canal deviation and amount of remnant structure, with shorter instrumentation time. SBF can be a suitable alternative for endodontic instrumentation in primary molars. motordriven motor driven molars Methods microCT micro CT type (SBF) SRF SRF) file timed again pre postinstrumentation post thickness p<0.05. p005 p p<0.05 . 0 05 (p<0.05) Results p>0.05. p>0.05 (p>0.05) p<0.001 p0001 001 (p<0.001 vs p<0.001, , Motordriven Motor p<0.001. Conclusion structure (SBF p00 p<0.0 (p<0.05 p>0.0 (p>0.05 p<0.00 p000 00 (p<0.00 p0 p<0. (p<0.0 p>0. (p>0.0 p<0 (p<0. p>0 (p>0. p< (p<0 p> (p>0 (p< (p> (p

Resumo Objetivo: Avaliar os resultados da instrumentação endodôntica e o tempo de preparo de lima odontopediátrica ativada por motor (Sequence Baby File- SBF) em canais de molares decíduos prototipados. Métodos: Trinta espécimes foram escaneados em micro-CT e divididos em três grupos de acordo com o tipo de instrumentação: mecanizada odontopediátrica (SBF); mecanizada convencional; lima K manual. O tempo de instrumentação foi cronometrado. Após o preparo, os espécimes foram escaneados novamente. As imagens pré e pós-instrumentação foram sobrepostas e a quantidade de desvio do canal radicular e a espessura de resina remanescente foram mensurados. Para as análises de comparações entre os grupos foram realizados teste ANOVA seguido do teste de Tukey (p<0,05). Resultados: Não ocorreram diferenças estatisticamente significativas entre os grupos no desvio do canal radicular (p>0,05). Houve diferenças estatisticamente significativas na comparação entre terços radiculares (p<0,001), mas sem diferenças significativas na interação grupo vs. terço radicular (p>0,05). A instrumentação mecanizada apresentou desgaste estatisticamente maior do que a instrumentação manual (p<0,001), sem diferenças estatísticas entre a SBF e a lima mecanizada convencional. A instrumentação mecanizada teve menor tempo de trabalho quando comparado a instrumentação manual (p<0,001). Conclusão: A instrumentação mecanizada odontopediátrica demonstrou bons resultados em relação ao desvio do canal radicular e quantidade de estrutura remanescente, com menor tempo de instrumentação. A SBF pode ser uma alternativa adequada para a instrumentação endodôntica em molares decíduos. Objetivo Sequence File prototipados Métodos microCT micro CT (SBF) convencional cronometrado novamente pósinstrumentação pós mensurados p<0,05. p005 p p<0,05 . 0 05 (p<0,05) Resultados p>0,05. p>0,05 (p>0,05) p<0,001, p0001 p<0,001 , 001 (p<0,001) vs p<0,001. Conclusão (SBF p00 p<0,0 (p<0,05 p>0,0 (p>0,05 p000 p<0,00 00 (p<0,001 p0 p<0, (p<0,0 p>0, (p>0,0 (p<0,00 p<0 (p<0, p>0 (p>0, p< (p<0 p> (p>0 (p< (p> (p

Abstract The aim of the present study was to estimate the population coverage of recording food intake markers in Brazil’s Food and Nutrition Surveillance System (Sisvan) and mean annual percent change (APC) in coverage according to the system used for data entry (e-SUS APS and Sisvan Web). We conducted an ecological time series study of the period 2015-2019. The data were stratified into region and age group. APC in coverage was calculated using Prais-Winsten regression and the correlation between APC and HDI, GDP per capita and primary healthcare coverage was assessed using Spearman’s correlation coefficient. Population coverage of recording food intake markers at national level was 0.92% in 2019. Mean APC in coverage throughout the period was 45.63%. The region and age group with the highest coverage rate were the Northeast (4.08%; APC=45.76%, p<0.01) and children aged 2-4 years (3.03%; APC=34.62%, p<0.01), respectively. There was an upward trend in data entry using e-SUS APS, to the detriment of Sisvan Web. There was a positive correlation between APC in coverage using e-SUS APS and HDI and GDP per capita in some age groups. Population coverage of recording Sisvan food intake markers remains low across the country. The e-SUS APS has the potential to be an important strategy for expanding food and nutrition surveillance. Brazils Brazil s (Sisvan (APC eSUS e SUS Web . Web) 20152019. 20152019 2015 2019 2015-2019 PraisWinsten Prais Winsten Spearmans Spearman coefficient 092 0 92 0.92 4563 45 63 45.63% 4.08% 408 4 08 (4.08% APC4576 76 APC=45.76% p<0.01 p001 p 01 24 2 2- 3.03% 303 3 03 (3.03% APC3462 34 62 APC=34.62% p<0.01, , respectively groups country surveillance 2015201 201 2015-201 09 9 0.9 456 6 45.63 4.08 40 (4.08 APC457 7 APC=45.76 p<0.0 p00 3.03 30 (3.03 APC346 APC=34.62 201520 20 2015-20 0. 45.6 4.0 (4.0 APC45 APC=45.7 p<0. p0 3.0 (3.0 APC34 APC=34.6 20152 2015-2 45. 4. (4. APC4 APC=45. p<0 3. (3. APC3 APC=34. 2015- (4 APC=45 p< (3 APC=34 ( APC=4 APC=3 APC=

Resumo O objetivo deste estudo foi estimar a cobertura populacional e a taxa de incremento anual (TIA) média, em âmbito nacional, do registro de marcadores do consumo alimentar do Sistema de Vigilância Alimentar e Nutricional (Sisvan), entre 2015 e 2019, considerando a entrada dos dados via Estratégia e-SUS APS e Sisvan Web. Trata-se de estudo ecológico de séries temporais, com estratificação por macrorregiões e faixas etárias. A TIA da cobertura foi calculada utilizando regressão de Prais-Winsten e a correlação com IDH, PIB per capita e cobertura da APS foi avaliada por teste de Spearman. A cobertura populacional do registro de marcadores de consumo alimentar no país foi de 0,92% em 2019, com TIA significante de 45,63% desde 2015. As maiores coberturas foram observadas na região Nordeste (4,08%; TIA=45,76%, p<0,01) e em crianças entre 2 e 4 anos (3,03%; TIA=34,62%, p<0,01). Houve tendência crescente para a entrada dos dados via e-SUS APS, em detrimento do Sisvan Web. A TIA da cobertura dos registros via e-SUS APS exibiu correlação positiva com IDH e PIB per capita em alguns recortes etários. A cobertura populacional do registro de marcadores de consumo alimentar do Sisvan ainda se mostra incipiente no país e o e-SUS APS parece ser uma estratégia relevante para sua expansão. (TIA média nacional Sisvan, , (Sisvan) 201 2019 eSUS SUS Web Tratase Trata temporais etárias PraisWinsten Prais Winsten Spearman 092 0 92 0,92 4563 45 63 45,63 4,08% 408 08 (4,08% TIA4576 76 TIA=45,76% p<0,01 p001 p 01 3,03% 303 3 03 (3,03% TIA3462 34 62 TIA=34,62% p<0,01. . etários expansão (Sisvan 20 09 9 0,9 456 6 45,6 4,08 40 (4,08 TIA457 7 TIA=45,76 p<0,0 p00 3,03 30 (3,03 TIA346 TIA=34,62 0, 45, 4,0 (4,0 TIA45 TIA=45,7 p<0, p0 3,0 (3,0 TIA34 TIA=34,6 4, (4, TIA4 TIA=45, p<0 3, (3, TIA3 TIA=34, (4 TIA=45 p< (3 TIA=34 ( TIA=4 TIA=3 TIA=

ABSTRACT Lettuce seeds usually show germination problems that can be related to dormancy and or thermoinhibition, as well as to the genotype constitution. The knowledge of the temperature at which the thermoinhibition process begins, as well as the influence of the age of the seed on its germination, is extremely important to establish more suitable parameters for the selection of higher genotypes in breeding programs. The objective of this work was to evaluate the seed germination of three lettuce cultivars according to the enviromental temperature and the age of the seeds. The cultivars Everglades (tolerant to thermoinhibition), Luisa (medium tolerant) and Verônica (sensitive) were used. Seeds of each cultivar were evaluated by the standard germination test, first count test, germination speed index and germination test of remaining seeds. The analyses were performed at four environmental temperatures and in seven storage periods after harvest. None of the cultivars showed primary dormancy. The tolerance to thermoinhibition showed by cultivars Everglades and Luisa and the sensitivity of cultivar Verônica were confirmed. The most suitable temperature for differentiating tolerant and sensitive thermoinhibition genotypes occurred from 30.5 ºC and 260 days after harvest. constitution begins programs , thermoinhibition) medium (sensitive used harvest confirmed 305 30 5 30. 26 3 2

Resumo O objetivo deste estudo foi estimar a cobertura populacional e a taxa de incremento anual (TIA) média, em âmbito nacional, do registro de marcadores do consumo alimentar do Sistema de Vigilância Alimentar e Nutricional (Sisvan), entre 2015 e 2019, considerando a entrada dos dados via Estratégia e-SUS APS e Sisvan Web. Trata-se de estudo ecológico de séries temporais, com estratificação por macrorregiões e faixas etárias. A TIA da cobertura foi calculada utilizando regressão de Prais-Winsten e a correlação com IDH, PIB per capita e cobertura da APS foi avaliada por teste de Spearman. A cobertura populacional do registro de marcadores de consumo alimentar no país foi de 0,92% em 2019, com TIA significante de 45,63% desde 2015. As maiores coberturas foram observadas na região Nordeste (4,08%; TIA=45,76%, p<0,01) e em crianças entre 2 e 4 anos (3,03%; TIA=34,62%, p<0,01). Houve tendência crescente para a entrada dos dados via e-SUS APS, em detrimento do Sisvan Web. A TIA da cobertura dos registros via e-SUS APS exibiu correlação positiva com IDH e PIB per capita em alguns recortes etários. A cobertura populacional do registro de marcadores de consumo alimentar do Sisvan ainda se mostra incipiente no país e o e-SUS APS parece ser uma estratégia relevante para sua expansão.

Abstract The aim of the present study was to estimate the population coverage of recording food intake markers in Brazil’s Food and Nutrition Surveillance System (Sisvan) and mean annual percent change (APC) in coverage according to the system used for data entry (e-SUS APS and Sisvan Web). We conducted an ecological time series study of the period 2015-2019. The data were stratified into region and age group. APC in coverage was calculated using Prais-Winsten regression and the correlation between APC and HDI, GDP per capita and primary healthcare coverage was assessed using Spearman’s correlation coefficient. Population coverage of recording food intake markers at national level was 0.92% in 2019. Mean APC in coverage throughout the period was 45.63%. The region and age group with the highest coverage rate were the Northeast (4.08%; APC=45.76%, p<0.01) and children aged 2-4 years (3.03%; APC=34.62%, p<0.01), respectively. There was an upward trend in data entry using e-SUS APS, to the detriment of Sisvan Web. There was a positive correlation between APC in coverage using e-SUS APS and HDI and GDP per capita in some age groups. Population coverage of recording Sisvan food intake markers remains low across the country. The e-SUS APS has the potential to be an important strategy for expanding food and nutrition surveillance.

Abstract Lagoa do São Bento is a coastal restinga wetland, remnant of a paleolake, located in Maricá, RJ. The study aimed to inventory native aquatic plants, make a floristic comparison with other coastal lagoons and analyze the regeneration of this community after anthropic impacts. In the floristic analysis of aquatic plants, 45 species were listed, 39 of which are Angiosperms and six are Ferns. Aeschynomene paniculata, Hymenachne amplexicaulis, Montrichardia linifera and Torenia thouarsii are new records for the municipality and Tabebuia cassinoides is threatened. Emerging plants (21 spp.) stand out, followed by amphibians (16 spp.), free floating (4 spp.), fixed floating (3 spp.) and tolerant (1 sp.). The comparison showed greater similarity with the Jacarepiá lagoon, in Saquarema, sharing 21 species. The phytosociological inventory listed 87 species, 83 of which were Angiosperms and four Ferns. The species with the highest IVI were: Fuirena umbellata, Pleroma gaudichaudianum, Xyris jupicai, Typha domingensis, Salvinia aff. auriculata, Eleocharis interstincta, Rhynchospora gigantea, Nymphoides humboldtiana, Nymphaea caerulea and Clitoria laurifolia. Shannon, Simpson and equity indexes were 3.83, 0.03 and 0.85, respectively. Native aquatic species represent the majority of the total inventoried (54%), with a considerable supply of exotic and ruderal, whose colonization reflects the anthropic interventions. wetland paleolake Maricá RJ impacts 4 3 Ferns paniculata amplexicaulis threatened (2 spp. spp out 16 spp., , ( 1 sp.. sp sp. . sp.) lagoon Saquarema 2 8 umbellata gaudichaudianum jupicai domingensis aff auriculata interstincta gigantea humboldtiana laurifolia Shannon 383 3.83 003 0 03 0.0 085 85 0.85 respectively 54%, 54 54% (54%) ruderal interventions 38 3.8 00 0. 08 0.8 5 (54% 3. (54 (5

Resumo A Lagoa do São Bento é uma área úmida costeira de restinga, resquício de uma paleolagoa, localizada em Maricá, RJ. O estudo objetivou inventariar as plantas aquáticas nativas, fazer a comparação florística com outras lagoas costeiras e analisar a regeneração dessa comunidade após impactos antrópicos. Na análise florística de plantas aquáticas foram listadas 45 espécies, das quais 39 são Angiospermas e seis são Samambaias. Aeschynomene paniculata, Hymenachne amplexicaulis, Montrichardia linifera e Torenia thouarsii são novos registros para o município e Tabebuia cassinoides é ameaçada de extinção. Sobressaem as plantas emergentes (21 spp.), seguida de anfíbias (16 spp.), flutuante livres (4 spp.), flutuante fixas (3 spp.) e tolerantes (1 sp.). A comparação mostrou maior similaridade com a lagoa de Jacarepiá, em Saquarema, compartilhando 21 espécies. O inventário fitossociológico listou 87 espécies, sendo 83 Angiospermas e quatro Samambaias. As espécies com maior IVI foram: Fuirena umbellata, Pleroma gaudichaudianum, Xyris jupicai, Typha domingensis, Salvinia aff. auriculata, Eleocharis interstincta, Rhynchospora gigantea, Nymphoides humboldtiana, Nymphaea caerulea e Clitoria laurifolia. Os índices de Shannon, Simpson e equabilidade foram 3,83, 0,03 e 0,85, respectivamente. As aquáticas nativas representam a maior parte do total inventariado (54%), havendo um aporte considerável de exóticas e ruderais, cuja colonização reflete as intervenções antrópicas. restinga paleolagoa Maricá RJ antrópicos 4 3 Samambaias paniculata amplexicaulis extinção (2 spp., spp spp. , 16 ( 1 sp.. sp sp. . sp.) Jacarepiá Saquarema 2 8 umbellata gaudichaudianum jupicai domingensis aff auriculata interstincta gigantea humboldtiana laurifolia Shannon 383 3,83 003 0 03 0,0 085 85 0,85 respectivamente 54%, 54 54% (54%) ruderais antrópicas 38 3,8 00 0, 08 0,8 5 (54% 3, (54 (5

ABSTRACT BACKGROUND: People living with life-limiting illnesses and their family caregivers consistently emphasize the importance of preparing for imminent death, with planned funerals being a common aspect of this preparation. Few studies have described the funeral rituals or post-mortem preferences of patients with cancer. OBJECTIVE: To evaluate the percentage of patients with cancer who wish to be cremated and to identify the factors associated with this preference. DESIGN AND SETTING: Cross-sectional study conducted at Barretos Cancer Hospital. METHODS: A total of 220 patients with cancer completed a Sociodemographic and Clinical Questionnaire, the Duke University Religiosity Index, and burial or cremation preferences. Binary Logistic Regression was performed to identify independent variables associated with cremation. RESULTS: Of the 220 patients, 25.0% preferred cremation and 71.4% preferred burial. Talks about death with family or close friends in their daily life (odds ratio, OR = 2.89; P = 0.021), patients that answered “other” (unsure, tends not be true and not true) for religious beliefs are what really lie behind my whole approach to life (OR = 20.34; P = 0.005), and education 9 to 11 years (OR = 3.15; P = 0.019) or ≥ 12 years (OR = 3.18; P = 0.024) were associated with cremation preference. CONCLUSION: Most patients with Cancer in Brazil prefer burial after death. Discussions about death, religious beliefs and involvement, and educational level seem to influence the preference for cremation. A deeper understanding of ritual funeral preferences and their associated factors may guide policies, services, and health teams in promoting the quality of dying and death. BACKGROUND lifelimiting limiting preparation postmortem post mortem OBJECTIVE SETTING Crosssectional Cross sectional Hospital METHODS 22 Questionnaire Index RESULTS 250 25 0 25.0 714 71 4 71.4 odds ratio 2.89 289 2 89 0.021, 0021 0.021 , 021 0.021) other “other unsure, unsure (unsure 20.34 2034 20 34 0.005, 0005 0.005 005 0.005) 1 3.15 315 3 15 0.019 0019 019 3.18 318 18 0.024 0024 024 CONCLUSION involvement policies services 25. 7 71. 2.8 28 8 002 0.02 02 20.3 203 000 0.00 00 3.1 31 0.01 001 01 2. 0.0 20. 3. 0.

ABSTRACT Background: SARS-CoV-2 virus originated in Wuhan (China) in December (2019) and quickly spread worldwide. Antigen tests are rapid diagnostic tests (RDT) that produce results in 15-30 min and are an important tool for the scale-up of COVID-19 testing. COVID-19 diagnostic tests are authorized for self-testing at home in some countries, including Brazil. Widespread COVID-19 diagnostic testing is required to guide public health policies and control the speed of transmission and economic recovery. Methods: Patients with suspected COVID-19 were recruited at the Hospital da Baleia (Belo Horizonte, Brazil). The SARS-CoV-2 antigen-detecting rapid diagnostic tests were evaluated from June 2020 to June 2021 using saliva, nasal, and nasopharyngeal swab samples from 609 patients. Patient samples were simultaneously tested using a molecular assay (RT-qPCR). Sensitivity, specificity, accuracy, and positive and negative predictive values were determined using the statistical program, MedCalc, and GraphPad Prism 8.0. Results: The antigen-detecting rapid diagnostic tests displayed 98% specificity, 60% sensitivity, 96% positive predictive value, and moderate concordance with RT-qPCR. Substantial agreement was found between the two methods for patients tested < 7 days of symptom onset. Conclusions: Our findings support the use of Ag-RDT as a valuable and safe diagnostic method. Ag-RDT was also demonstrated to be an important triage tool for suspected COVID-19 patients in emergencies. Overall, Ag-RDT is an effective strategy for reducing the spread of SARS-CoV-2 and contributing to COVID-19 control. Background SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- China (China 2019 (2019 worldwide RDT (RDT 1530 15 30 15-3 scaleup scale up COVID19 COVID 19 COVID-1 selftesting self countries Brazil recovery Methods Belo Horizonte . Brazil) antigendetecting antigen detecting 202 saliva nasal 60 RTqPCR. RTqPCR RT qPCR (RT-qPCR) Sensitivity specificity accuracy program MedCalc 80 8 0 8.0 Results 98 sensitivity 96 value qPCR. RT-qPCR onset Conclusions AgRDT Ag method emergencies Overall SARS-CoV 201 (201 153 1 3 15- COVID1 COVID- 20 6 (RT-qPCR 8. 9 (20 (2 (