Pesquisa | SciELO

RESUMEN En este trabajo analizamos la valoración que el alumnado universitario realiza de su trabajo de composición cooperativa durante un semestre académico. Se contemplan, entre otras, las variables de formación musical y de género. El alumnado compone una canción para un aula de Educación Primaria. Son 89 participantes, de los cuales solo 26 declaran haber estudiado música en centros especializados. Los resultados muestran que el alumnado participante se encuentra, en general, muy satisfecho con el trabajo realizado, en especial las mujeres y los estudiantes con conocimientos musicales. La implicación fue alta, y se percibe que la enculturación tonal en la población general repercute en que determinadas actividades de creatividad musical que podríamos considerar complejas pueden, mediante el trabajo colaborativo, ejercerse en contextos ajenos a los que derivan de una formación musical especializada.

ABSTRACT In this paper we analyse how university students evaluate their cooperative composition work during an academic semester. Variables such as musical training and gender, among others, are considered. The students compose a song for a primary school classroom. They were 89 participants, of whom only 26 reported having studied music at specialized schools. The results show that the participating students are, in general, very satisfied with the work carried out, especially the women and students with previous musical knowledge. The involvement was high and it is perceived that tonal enculturation in the general population has an impact on the fact that certain musical creativity activities, that we could consider complex, can be exercised through collaborative work, in contexts other than those derived from specialized musical training.

RESUMO Neste artigo analisamos a forma como os estudantes universitários avaliam o seu trabalho de composição cooperativa durante um semestre académico. São tidas em conta as variáveis de formação musical e género, entre outras. Os alunos compõem uma canção para uma sala de aula da educação básica. Participaram 89 estudantes, dos quais apenas 26 declararam ter estudado música em centros especializados. Os resultados mostram que os alunos participantes estão, em geral, muito satisfeitos com o trabalho realizado, especialmente as mulheres e os alunos com conhecimentos musicais. O envolvimento foi elevado, e percebe-se que a enculturação tonal na população em geral significa que certas atividades de criatividade musical que poderíamos considerar complexas podem, através do trabalho colaborativo, ser exercidas em contextos diferentes dos que derivam de uma formação musical especializada.

https://doi.org/10.25749/sis.30958

Ana Fidelia Quiros Moret, un ejemplo para la formación de valores desde su trayectoria deportiva
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Cañizares Hernández, Marta

; Dávila Lorenzo, Marianela

; Calero Morales, Santiago

Conrado

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Abr 2024, Volume 20 Nº 97 Páginas 189 - 195

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT The objective of this work is to analyze the manifestation of resilient behavior and relevant volitional qualities as an example in the formation of values from the sports career of the athlete Ana Fidelia Quiros Moret, a transcendental Cuban athlete, Olympic and world athletics medalist. A life history is carried out through qualitative (analytical) research to assess the manifestation of these relevant psychological aspects that characterized their results and triumphs in sport. Case study methods, interviews, documentary analysis, as well as triangulation of sources and methods are used. As results, the main periods of her sporting career are described and analyzed and the relevance of her resilient behavior and her volitional traits as a female athlete are determined: perseverance, persistence, self-control, self-control, courage, discipline, specifically manifested in the face of a traumatic life event that It affects a stage of your activity as an athlete and the body transformation suffered in addition to the influence of the high loads of high-performance sport. This research will allow Physical Culture students and athletes to learn about the exemplary characteristics and values of this outstanding woman that transcend the field of Cuban and world sports.

RESUMEN El presente trabajo tiene como objetivo analizar la manifestación de la conducta resiliente y cualidades volitivas relevantes como ejemplo en la formación de valores desde en la trayectoria deportiva de la atleta Ana Fidelia Quiros Moret, trascendental deportista cubana, medallista olímpica y mundial de atletismo. Se realiza una historia de vida mediante la investigación cualitativa (analítica) para valorar la manifestación de estos aspectos psicológicos relevantes que caracterizaron sus resultados y triunfos en el deporte. Se utilizan los métodos de estudio de caso, entrevistas, análisis documental, así como la triangulación de fuentes y métodos. Como resultados se describen y analizan los períodos principales de su trayectoria deportiva y se determina la relevancia de su conducta resiliente, sus rasgos volitivos como mujer deportista: perseverancia, persistencia, autocontrol, autodominio, valentía, disciplina, específicamente manifiesta ante un evento vital traumático que afecta una etapa de su actividad como atleta y la transformación corporal sufrida además de la influencia de las altas cargas del deporte de alto rendimiento. La presente investigación permitirá que los estudiantes de Cultura Física y los deportistas, conozcan las características de ejemplaridad y los valores de esta destacada mujer que trascienden en el ámbito del deporte cubano y mundial.

Nuevo ensayo del grupo de “Biología y Agroecología de las Malas hierbas (BAMh)”: modelos de emergencia para malas hierbas de verano
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Sousa-Ortega, Carlos

; Royo-Esnal, Aritz

; Escorial, María Concepción

; Loureiro, Iñigo

; Lezáun, Juan Antonio

; Figarola, Jordi Izquierdo

; López-Martínez, Nuria

; Osca, José María

; León, Ana Isabel Marí

; Calha, Isabel

; Chamorro-Lorenzo, Lourdes

; Arias-Martín, María

Revista de Ciências Agrárias

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Mar 2024, Volume 47 Nº 1 Páginas 681 - 690

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract The Weed Biology and Agroecology group (BAMh) of the Spanish Society of Weed Science (SEMh) is currently composed of 15 people working in 4 universities; Universitat de Lleida (UdL), Universitat Politècnica de València (UPV), Universidad de Sevilla (US) and Universitat Politècnica de Catalunya (UPC) and in 5 research centers in Spain and Portugal: Centro de Investigación y Tecnología Agraria de Aragón (CITA), CN Instituto Nacional de Investigaciones y Tecnología Agraria y Alimentaria (INIA-CSIC), Centro de Investigaciones Científicas y Tecnológicas de Extremadura (CICYTEX), Instituto Andaluz de Investigación y Formación Agraria, Pesquera, Alimentaria y de la Producción Ecológica (IFAPA), Instituto Navarro de Tecnologías e Infraestructuras Agroalimentaria (INTIA) and Instituto Nacional de Investigação Agrária e Veterinária (INIAV). This group has initiated a new trial (2023-2025) to validate for the Iberian Peninsula the emergence models developed in Italy for the weeds Chenopodium album L., Sorghum halepense L., Abutilon theophrasti Medik, Digitaria sanguinalis (L.) Scop. and Amaranthus retroflexus L. The seeds collected by the groups at their locations will be sown in mid-autumn in experimental plots in Aragón, Barcelona, Sevilla, Córdoba, Lleida, Madrid, Valencia, Navarra and Oeiras (Portugal). The emergence will be evaluated and the base, optimum and ceiling temperatures and the base water potential will be obtained under controlled conditions for the germination of those species that do not fit the model. The recalibration and optimization of these models for their application in the Iberian Peninsula will contribute to achieve an integrated management of weeds in summer crops.

Resumen El grupo de Biología y Agroecología de las Malas Hierbas (BAMh) de la Sociedad Española de Malherbología (SEMh) está actualmente integrado por 15 personas que trabajan en 4 universidades; Universitat de Lleida (UdL), Universitat Politècnica de València (UPV), Universidad de Sevilla (US) y Universitat Politècnica de Catalunya (UPC) y en 5 centros de investigación de España y Portugal: el Centro de Investigación y Tecnología Agraria de Aragón (CITA), el CN Instituto Nacional de Investigaciones y Técnología Agraria y Alimentaria (INIA-CSIC), el Centro de Investigaciones Científicas y Tecnológicas de Extremadura (CICYTEX), el Instituto Andaluz de Investigación y Formación Agraria, Pesquera, Alimentaria y de la Producción Ecológica (IFAPA), el Instituto Navarro de Tecnologías e Infraestructuras Agroalimentaria (INTIA) y el Instituto Nacional de Investigação Agrária e Veterinária (INIAV). Se ha planteado un nuevo ensayo (2023-2025) para validar en la Península Ibérica los modelos de emergencia desarrollados en Italia para las malas hierbas Chenopodium album L., Sorghum halepense L., Abutilon theophrasti Medik., Echinochloa crus-galli (L.) Beauv., Digitaria sanguinalis (L.) Scop. y Amaranthus retroflexus L. Las semillas recogidas en 2023 se sembraran a mediados de otoño en parcelas experimentales de Aragón, Barcelona, Sevilla, Córdoba, Lleida, Madrid, Valencia, Navarra y Oeiras (Portugal). Se evaluará la emergencia y se obtendrá en condiciones controladas, la temperatura base, óptima, techo y el potencial hídrico base de las especies cuya germinación no se ajuste al modelo. La recalibración de estos modelos para la Península Iberica contribuirá a conseguir un adecuado manejo integrado de las malas hierbas en cultivos de verano.

https://doi.org/10.19084/rca.35128

Germinación e inducción de callo para la producción de alcaloides de dos especies de Lupinus en condiciones in vitro
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Salcedo-Morales, Guadalupe

; Morales-Muñoz, Karina

; Paredes-Sastre, Guadalupe

; Valdovinos-Bazaldua, José Alfredo

; Castrejón-Lorenzo, Ana Belem

; Rosales-de la Vega, Franco

; León-Romero, Yatzil

; Montes-Hernández, Edith

; Mejía-Vigueras, Israel

; Bermúdez-Torres, Kalina

Polibotánica

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2024, Nº 57 Páginas 183 - 197

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

AbstractLupinus synthesizes quinolizidine alkaloids (AQ) as a defense strategy against herbivores. These compounds have a wide variety of applications; however, it is necessary to have a sufficient amount of raw material to satisfy market needs. The species rich in these compounds are wild species, which limits the obtaining of the raw material. One of the strategies for obtaining raw material and producing secondary metabolites is the use of biotechnological tools such as plant tissue culture. In this work we report the characterization of germination, callus induction of Lupinus bilineatus and L. montanus and the characterization of in vitro growth and AQ production. The culture medium and seed scarification protocol allowed the germination of seeds of both species with percentages at 12 days of 100% for L. bilineatus and 74% for L. montanus. With respect to callus induction, a sweep of indolbutyric acid (2,4-D) and cinetin (CIN) concentrations was employed using leaf, stem and root as explants. The best response for callus induction for both species was presented using root with a combination of 2 mg L-1 of 2,4-D and 1 mg L-1 of CIN for L. bilineatus and 1 mg L-1 of 2,4-D and 0.5 mg L-1 of CIN for L. montanus, in both cases friable callus was obtained with two colorations: green and beige. Growth and AQ production were characterized for green callus, since AQ are synthesized in photosynthetic tissues. The growth kinetics shows a characteristic three-phase curve, an adaptation phase extending to day seven, the fastest growth phase and finally a senescence phase starting on day 18. AQ production was observed on day 21. This work contributes to the knowledge of germination behavior, the induction of dedifferentiated tissue and the growth and production of alkaloids in a callus culture in two species of Lupinus, L. montanus and L. bilineatus, both with potential in the chemical and agrochemical industry.

Resumen Lupinus sintetiza alcaloides quinolizidínicos (AQ) como estrategia de defensa en contra de herbívoros. Estos compuestos tienen una amplia variedad de aplicaciones; sin embargo, es necesario contar con la suficiente cantidad de materia prima para satisfacer las necesidades del mercado. Las especies ricas en estos compuestos son especies silvestres, lo que limita la obtención de la materia prima. Una de las estrategias para la obtención de materia prima y la producción de metabolitos secundarios es el uso de herramientas biotecnológicas como el cultivo de tejidos vegetales. En este trabajo se reporta la caracterización de la germinación, la inducción de callo de Lupinus bilineatus y L. montanus y la caracterización del crecimiento in vitro y producción de AQ. El medio de cultivo y el protocolo de escarificación permitieron la germinación de las semillas de ambas especies a los 12 días con porcentajes de 100% para L. bilineatus y de 74% para L. montanus. Con respecto a la inducción de callo, se empleó un barrido de concentraciones de ácido 2,4-diclorofenoxiacético (2,4-D) y cinetina (CIN) utilizando como explante cotiledón, hipocótilo y raíz. La mejor respuesta para la inducción de callo para ambas especies se presentó usando raíz con una combinación de 2 mg L-1 de 2,4-D y 1 mg L-1 de CIN para L. bilineatus y 1 mg L-1 de 2,4-D y 0.5 mg L-1 de CIN para L. montanus, en ambos casos se obtuvo callo friable con dos coloraciones: verde y beige. El crecimiento y la producción de AQ se caracterizaron para el callo verde, pues los AQ se sintetizan en tejidos fotosintéticos. La cinética de crecimiento muestra una característica curva de tres fases, una fase de adaptación que se alarga hasta el día siete, la fase de crecimiento más rápido y finalmente una fase de senescencia que inicia el día 18. La producción de AQ se observó el día 21. Este trabajo contribuye al conocimiento del comportamiento de la germinación, la inducción de tejido desdiferenciado y el crecimiento y producción de alcaloides en un cultivo de callo de dos especies de Lupinus, L. montanus y L. bilineatus, ambas con potencial en la industria química y de agroquímicos.

https://doi.org/10.18387/polibotanica.57.11

Feline rabies caused by a viral variant of insectivorous bat
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Amado, Caio Maurício

; Alberti, Tainá dos Santos

; Marcolongo-Pereira, Clairton

; Sousa, Carolina Gonçalves de

; Lorenzo, Cíntia de

; Schild, Ana Lucia

; Raffi, Margarida Buss

; Sallis, Eliza Simone Viégas

Ciência Rural

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2024, Volume 54 Nº 10 elocation e20230353

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO: A raiva é uma enfermidade viral infectocontagiosa, invariavelmente fatal, causada por Lyssavirus, que afeta o sistema nervoso central de mamíferos domésticos e silvestres. O objetivo deste estudo foi alertar para a importância de morcegos insetívoros e dos felinos domésticos na epidemiologia da raiva. Para isso, foram analisados dois casos de raiva registrados em gatos domésticos na região sudeste do Rio Grande do Sul. Os diagnósticos basearam-se nas alterações histológicas e na marcação positiva para o vírus na imunofluorescência direta com confirmação por prova biológica, avaliação imuno-histoquímica e identificação da variante do vírus rábico por reação de polimerase em cadeia. No Brasil tem sido observado uma mudança no perfil epidemiológico da raiva, no qual os morcegos assumem papel principal na cadeia atual de transmissão da doença.Chama-se a atenção que a variante viral antigênica AgV-4, própria do morcego insetívoro Tadarida brasiliensis, foi identificada nos felinos domésticos afetados neste estudo. RESUMO infectocontagiosa fatal Lyssavirus silvestres isso Sul basearamse basearam se biológica imunohistoquímica imuno histoquímica doença.Chamase doençaChamase doença.Chama doença Chama AgV4, AgV4 AgV 4, 4 AgV-4 brasiliensis Chamase doençaChama AgV-

ABSTRACT: Rabies is an invariably fatal infectious-contagious viral disease caused by viruses in the genus Lyssavirus, which affects the central nervous system of domestic and wild mammals. This study draws attention to the importance of insectivorous bats and domestic cats in the epidemiology of rabies. For this, two cases of rabies registered in domestic cats in the southeast region of Rio Grande do Sul were analyzed. Diagnoses were based on histological alterations and positive staining for the virus in direct immunofluorescence with confirmation by biological test, immunohistochemical evaluation and identification of the rabies virus variant by polymerase chain reaction. In Brazil, a change in the epidemiological profile of rabies has been observed, in which bats play a major role in the current chain of transmission of the disease. It is noteworthy, that the antigenic viral variant AgV-4, typical of the insectivorous bat Tadarida brasiliensis, was identified in the domestic cats affected in this study. ABSTRACT infectiouscontagious infectious contagious Lyssavirus mammals analyzed test reaction Brazil observed noteworthy AgV4, AgV4 AgV 4, 4 AgV-4 brasiliensis AgV-

https://doi.org/10.1590/0103-8478cr20230353

Gestión de seguridad psicológica, su efectividad durante la emergencia sanitaria por COVID-19
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Gutiérrez Alvarez, Ana Karina

; Pupo Guisado, Beatriz

; Lorenzo Ruiz, Alexis

; Mayo Parra, Israel

; Cruz Almaguer, Aymara Yusimy

Anales de la Academia de Ciencias de Cuba

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Dez 2023, Volume 13 Nº 4 elocation e1471

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: The search for solutions to the mental fitness problem of health personnel reported during the COVID-19 pandemic points to the management of their psychological safety as a novel alternative. The objective of this work was to evaluate the effectiveness of psychological safety management carried out through a professional action protocol, during the COVID-19 pandemic. Methods: It was carried out a study with a pre-experimental design from March 2020 to August 2021, in four phases of the COVID-19 pandemic, defined for the purposes of the research as outbreak, new normality, resurgence and Delta wave. It was implemented the protocol for the management of psychological safety. 1416 subjects and 236 work teams from high-risk areas in a hospital institution participated. They were applied McNemar statistical tests and binary logistic regression. Results: It was obtained an incidence of mental health disorders of 14.2%. Statistical tests showed that the percentage differences in the variables dependent on management were due to the implemented protocol. They were identified the independent variables that best explained the state of reasonable psychological safety during work and the safe behavior of the work team. Conclusions: it was obtained evidence of the effectiveness of the protocol implemented in the hospital institution during the health emergency by COVID-19 that justifies its use in similar situations that arise in the future.

RESUMEN Introducción: La búsqueda de soluciones al problema de la salud mental del personal sanitario reportado durante la pandemia de COVID-19 señala la gestión de su seguridad psicológica como una alternativa novedosa. Este trabajo tiene por objetivo evaluar la efectividad de la gestión de la seguridad psicológica realizada a través de un protocolo de actuación profesional, durante la pandemia de COVID-19. Métodos: Se realizó un estudio con diseño preexperimental desde marzo de 2020 a agosto de 2021, en 4 fases de la pandemia de COVID-19, definidas a los efectos de la investigación en: brote, nueva normalidad, rebrote y oleada Delta. Se implementó el protocolo para la gestión de la seguridad psicológica. Participaron 1416 sujetos y 236 equipos de trabajo de las zonas de alto riesgo en una institución hospitalaria. Se aplicaron las pruebas estadísticas McNemar y regresión logística binaria. Resultados: Se obtuvo una incidencia de afectaciones de salud mental del 14,2 %. Las pruebas estadísticas mostraron que las diferencias porcentuales en las variables dependientes de la gestión se debieron al protocolo implementado. Se identificaron las variables independientes que mejor explicaron el estado de seguridad psicológica razonable durante el trabajo y el comportamiento seguro de equipo de trabajo. En conclusiones se obtuvieron evidencias de la efectividad del protocolo implementado en la institución hospitalaria durante la emergencia sanitaria por COVID-19 que justifican su empleo en situaciones similares que se presenten en el futuro

Un desafío terapéutico: la heterorresistencia en Mycobacterium tuberculosis
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Gamberale, Ana

; Bartoletti, Bruno

; Cruz, Víctor

; Matteo, Mario

; Latini, Cecilia

; Paul, Roxana

; Lorenzo, Federico

; Símboli, Norberto

; Palmero, Domingo

Medicina (Buenos Aires)

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Dez 2023, Volume 83 Nº 5 Páginas 799 - 803

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Mixed infection by Mycobacterium tuberculosis (Mtb) consists in the simultaneous coexistence in the same patient of two different strains of Mtb or 2 different variants of the same strain. When one of the variants selects for resistance mutations, it is called monoclonal heteroresistance (HTR); if there are 2 different strains, one sensitive and one resistant (or with different resis tance patterns), it is called polyclonal HTR. Three cases of HIV/AIDS patients are presented, all with repeated treatment adherence problems, in whom monoclonal HTR was diagnosed through Mtb complete genomic sequentiation with the coexistence of two variants of the same strain isolated from samples from lung and lymph nodes, with different resistance profiles in each case. It is important to consider the possibility of HTR, especially in patients with multiple previous therapeu tic attempts and high bacillary populations, such as in advanced AIDS, since this situation potentially com promises treatment results by coexisting sensitive and resistant variants of a strain (or strains).

Resumen Se considera infección mixta por Mycobacterium tuberculosis (Mtb) a la coexistencia en forma simul tánea y en un mismo paciente de 2 cepas diferentes de Mtb o 2 variantes distintas de la misma cepa. Cuando una de las variantes selecciona mutaciones de resistencia, se denomina heterorresistencia (HTR) monoclonal; en caso de que sean 2 cepas diferentes, una sensible y una resistente (o cepas con diferentes patrones de resistencia), se denomina HTR policlo nal. Se presentan 3 pacientes, HIV/sida, todos con reiterados problemas de adherencia al tratamiento, en los cuales a través de la secuenciación genómica completa de Mtb se diagnosticó HTR monoclonal con coexistencia de 2 variantes de la misma cepa aisladas de muestras de pulmón y ganglios linfáticos, con diferentes perfiles de resistencia en cada uno de los casos. Es importante pensar en la posibilidad de HTR, principalmente en pacientes con múltiples intentos terapéuticos previos y altas poblaciones bacilares, como en el sida avanzado, dado que esta situación compromete potencialmente los resultados del tratamiento al coexistir cepas o variantes de ce pas sensibles y resistentes.

Osteomielitis primaria de esternón
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Rodríguez Lorenzo, Patricia

; Martínez, Begoña Fernández

; Pérez Alba, Marta

; Ramírez Jaén, Clara

; Meana Morís, Ana R.

; Pérez Méndez, Carlos

Archivos argentinos de pediatría

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Nov 2023, Volume 121 Nº 5 Páginas 12 - 12

Resumo: Es | Texto: Es | PDF: Es

RESUMEN La osteomielitis primaria de esternón es muy infrecuente en niños, con menos de 100 casos publicados hasta la actualidad. Su presentación clínica es a menudo inespecífica, lo que causa un retraso en el diagnóstico. Se presentan dos nuevos casos de osteomielitis primaria de esternón. Ambos referían un cuadro de fiebre, malestar general, dolor torácico y rechazo del decúbito, con eritema preesternal en uno de los casos. La velocidad de sedimentación globular y la proteína C-reactiva estaban elevadas en ambos casos. El diagnóstico se confirmó mediante estudios de imagen y en un caso se aisló Staphylococcus aureus sensible a meticilina en el hemocultivo. Ambos se recuperaron sin complicaciones con tratamiento antibiótico. Debe tenerse en cuenta la osteomielitis primaria de esternón en el diagnóstico diferencial del dolor torácico, especialmente si se acompaña de fiebre, signos inflamatorios locales, intolerancia al decúbito o elevación de reactantes de fase aguda.

https://doi.org/10.5546/aap.2022-01449

Estudo do nível de atividade física, grau de resiliência e risco coronariano de acadêmicos do curso de Educação Física da Universidade do Estado do Pará
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Souza, Divaldo Martins de

; Saraiva, Arianne Camile Silva

; Dias, Letícia Alves

; Rocha, Ana Vitória Travassos

; Luz, Lorenzo Marcley Ramos

; Silva, Jennifer Fabiana Santos da

Motricidade

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Set 2023, Volume 19 Nº 3 Páginas 351 - 357

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Atividade Física (AF) é fator preventivo de doenças e de promoção de saúde. Resiliência (R) é reação positiva diante de uma catástrofe, ameaça ou situação estressante e risco coronariano (RC) é importante no estudo da saúde. O objetivo do estudo foi analisar e correlacionar os níveis de AF, R e RC nos acadêmicos do Curso de Educação Física da UEPA. Estudo de campo, analítico, comparativo e correlacional, realizado de março a maio de 2022 com 60 acadêmicos. Os dados foram coletados através do Questionário de Nível de AF de Baecke, Burema e Frijters (1982), do questionário da Escala de R adaptado por Pesce et al. (2005) e do questionário de avaliação do RC da Universidade Federal de Santa Maria (2000), tratados através dos valores absolutos e relativos, média e desvio padrão, teste χ2, t de Student, ANOVA one way e correlação de Pearson. Os resultados indicam maior prevalência de grau Bom de R, nível de AF Regular e nível de RC Remoto, índice de AF maior nas mulheres e RC nos homens, correlação entre a idade e R e negativa entre a AF e o RC, o que sugere R e RC adequados, porém AF inferior; os homens precisam melhorar sua AF e diminuir o RC.

ABSTRACT Physical Activity (PA) is a predictive factor of diseases and health promotion. Resilience (R) is a positive reaction in the face of a catastrophe, threat or stressful situation, and coronary risk (CR) is important in the study of health. This study aimed to analyse and correlate the levels of PA, R and CR in the students of the Physical Education Course of the UEPA. In addition to the field, analytic, comparative and correlational, conducted from March to May 2022 with 60 students, the data were collected through the Baecke PA Level Questionnaire, the R Scale questionnaire and the UFSM RC assessment questionnaire, treated using absolute and relative values, mean and standard deviation, χ2 test, Student t, ANOVA one way and Pearson correlation. The results indicate a higher prevalence of Good Grade of R, Level of Regular PA and Level of Remote CR, higher PA index in women and CR in men, correlation between age and R and negative between PA and CR, which suggests adequate R and CR, but lower PA; men need to improve their PA and decrease CR.

https://doi.org/10.6063/motricidade.31564

10.

Reposicionamiento del anticuerpo monoclonal humanizado cubano nimotuzumab en el tratamiento de pacientes con COVID-19
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Díaz Londres, Henrry

; Jiménez Armada, Jorge

; Hernández Martínez, Aray

; Abdo Cuza, Anselmo A.

; Hernández Sánchez, Yamilka

; Granado Rodríguez, Aylin

; Sepúlveda Figueroa, Sarahy

; Llanez Gregorich, Egda M.

; Torres Lahera, Mery L.

; Gómez Peire, Francisco

; Montero González, Teresita

; Zamora González, Yaneth

; Añé Kouri, Ana L.

; González Palomo, Addys

; Troche Concepción, Mayelin

; Medel Pérez, Loipa

; Luaces Alvarez, Patricia Lorenzo

; Estévez Iglesias, Daymys

; Saavedra Hernández, Danay

; Ramos Suzarte, Mayra

; Crombet Ramos, Tania

Anales de la Academia de Ciencias de Cuba

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Ago 2023, Volume 13 Nº 2 elocation e1263

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: Lung injury and STAT1 deficit can induce EGFR overexpression in SARS-CoV2 infected cells. Methods: Considering the role of EGFR in inflammation and fibrosis, a Phase I/II trial was done to evaluate the safety and preliminary effect of nimotuzumab, a humanized anti-EGFR antibody, in severe and high-risk moderate patients with COVID-19. Patients were able to receive other drugs included in the national protocol. Treatment consisted on nimotuzumab intravenous infusions, administered every 72 hours. Before launching the study, EGFR expression was confirmed by immunohistochemistry in 20 lung samples from COVID-19 deceased subjects. Results: They were included forty-one patients (31 severe/10 moderate) in the trial. The median age was 62 years and the main comorbidities were hypertension, diabetes, cardiovascular disease and obesity. Seven patients received one dose of nimotuzumab, 29 received 2 infusions while 5 subjects required 3 doses. The antibody was very safe. There were only 4 related adverse events in 2 subjects. Eight patients required invasive mechanical ventilation. The 14 day recovery rate was 82,9%. 90% in moderate patients and 80,64 % in severe patients. Inflammatory markers decreased overtime and interleukin-6 concentration diminished from 46,5 pg/ml to 14,51 pg/ml at day 7. None of the evaluated patients showed signs of fibrosis in the follow-up evaluation. After the use of nimotuzumab in 1,536 patients in the real-world scenario, a high recovery rate was achieved in severe and moderate patients (89,4% and 79.4%, respectively), which compares very favorably with the phase I/II trial data. Conclusions: our results suggest that nimotuzumab is a safe antibody that can reduce inflammation and avoid fibrosis in severe and moderate COVID-19 patients at high risk of aggravation.

RESUMEN Introducción: La lesión pulmonar y el déficit del transductor de señal y el activador de la transcripción 1 (STAT1) inducen la sobreexpresión de receptor del factor de crecimiento epidérmico (EGFR) en células infectadas con SARS-CoV-2. Métodos: Teniendo en cuenta el papel del EGFR en la inflamación y la fibrosis, se realizó un ensayo de fase I/II para evaluar la seguridad y el efecto del nimotuzumab, un anticuerpo anti-EGFR humanizado, en pacientes con COVID-19 graves y moderados. Los pacientes recibieron otros medicamentos incluidos en el protocolo nacional. El tratamiento consistió en infusiones intravenosas de nimotuzumab, administradas cada 72 h. Antes de iniciar el estudio, la expresión de EGFR se confirmó mediante inmunohistoquímica en 20 muestras de pulmón de sujetos fallecidos por COVID-19. Resultados: En el ensayo se incluyeron 41 pacientes (31 graves/10 moderados). La media de edad fue de 62 años y las principales comorbilidades fueron hipertensión, diabetes, enfermedad cardiovascular y obesidad. Recibieron una dosis de nimotuzumab 7 pacientes, 29 recibieron 2 infusiones mientras que 5 sujetos requirieron 3 dosis. El anticuerpo fue seguro. Solo se detectaron 4 eventos adversos en 2 sujetos. Requirieron ventilación mecánica invasiva 8 pacientes. La tasa de recuperación a los 14 días fue del 82,9 %: pacientes moderados 90 % y 80,64 % en pacientes graves. Los marcadores inflamatorios disminuyeron en el tiempo y la concentración de interleucina-6 disminuyó de 46,5 pg/ml a 14,51 pg/ml el día 7. Ninguno de los pacientes evaluados mostró signos de fibrosis en el seguimiento. Tras el uso del nimotuzumab en 1536 pacientes en las condiciones del mundo real, se logró una alta tasa de recuperación en los pacientes graves y moderados (89,4 y 79,4 %, respectivamente), lo cual se compara muy favorablemente con los datos del ensayo fase I/II. Conclusiones: estos resultados sugieren que el nimotuzumab es un anticuerpo seguro que puede reducir la inflamación y evitar la fibrosis en pacientes con COVID-19 graves y moderados.

11.

The landscape of hematology research in Brazil: an analysis of data from citation databases Brazil
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Paula, Erich Vinicius De

; Martins, Marcio Souza

; Lorenzo, Ana Luisa Bortoluzo De

; Duarte, Bruno Kosa Lino

; Rezende, Suely Meireles

; Costa, Fernando Ferreira

Hematology, Transfusion and Cell Therapy

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Jul 2023, Volume 45 Supl. 2 Páginas S57 - S67

Resumo: En | Texto: En | PDF: En

ABSTRACT Introduction: Scientometrics is the field concerned with measuring and analyzing academic literature, using specific metrics and data from bibliometric databases. Hematology is a broad area of science and medicine, from which several landmark scientific discoveries have emerged. Objective: The aim of this report is to provide a snapshot of the landscape of hematology research in Brazil, based on a comprehensive analysis of published studies in hematology whose authors were affiliated to Brazilian institutions from 1980 to 2020. Method: Articles, reviews and letters to the editor with at least one author affiliated to a Brazilian institution were retrieved from Incytes/Web of Science or Scopus databases. Importantly, only papers classified in the subject area “Hematology” by the embedded algorithms of each database were included. Results: Considering all published papers, Brazil is in the 22nd position, contributing with around 1.1% of papers in this period. A clear and sustained increase in publication output can be observed from the early 1990’s to the present moment. Publicly-funded higher education institutions were the main contributors to the development and consolidation of the hematology scientific community, which has grown in diversity, with an increasing number of contributions from private institutions. In regard to funding, public agencies have been and remain by large as the most important funder of research in hematology in Brazil. Conclusion: We suggest that continuous monitoring of the temporal trends of some of the data compiled in our report could potentially contribute to a clearer picture of the development of hematology research in Brazil. Introduction literature databases medicine emerged Objective 198 2020 Method Articles IncytesWeb Incytes Web Importantly “Hematology included Results nd position 11 1 1.1 period 1990s s 1990 moment Publiclyfunded Publicly funded community diversity funding Conclusion 19 202 1. 199 20 2

https://doi.org/10.1016/j.htct.2022.02.001

12.

Cross-cultural invariance of the Spanish version of the COVID-19 Assessment Scorecard to measure the perception of government actions against COVID-19 in Latin America Crosscultural Cross cultural COVID19 COVID 19 COVID-1 COVID1 1 COVID-
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Caycho-Rodríguez, Tomás

; Valencia, Pablo D.

; Ventura-León, José

; Carbajal-León, Carlos

; Vilca, Lindsey W.

; Reyes-Bossio, Mario

; Delgado-Campusano, Mariel

; Yupanqui-Lorenzo, Daniel E.

; Paredes-Angeles, Rubí

; Rojas-Jara, Claudio

; Gallegos, Miguel

; Cervigni, Mauricio

; Martino, Pablo

; Polanco-Carrasco, Roberto

; Palacios, Diego Alejandro

; Moreta-Herrera, Rodrigo

; Samaniego-Pinho, Antonio

; Rivera, Marlon Elías Lobos

; Figares, Andrés Buschiazzo

; Puerta-Cortés, Diana Ximena

; Corrales-Reyes, Ibraín Enrique

; Calderón, Raymundo

; Gallegos, Walter L. Arias

; Petzold, Olimpia

; Camargo, Andrés

; Torales, Julio

; Blanco, J. Arkangel Monge

; González, Pedronel

; Smith-Castro, Vanessa

; Rivera, Wendy Yamilet Matute

; Ferrufino-Borja, Daniela

; Ceballos-Vásquez, Paula

; Muñoz-del-Carpio-Toia, Agueda

; Palacios, Jorge

; Burgos-Videla, Carmen

; León, Ana María Eduviges Florez

; Vergara, Ibeth

; Vega, Diego

; Barria-Asenjo, Nicol A.

; Schulmeyer, Marion K.

; Rios, Hassell Tatiana Urrutia

; Lira, Arelly Esther Lira

Psicologia: Reflexão e Crítica

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2023, Volume 36 elocation 34

Resumo: En | Texto: En | PDF: En

Abstract Objectives The present study aimed to evaluate the measurement invariance of a general measure of the perception of governmental responses to COVID-|19 (COVID-SCORE-10) in the general population of 13 Latin American countries. Methods A total of 5780 individuals from 13 Latin American and Caribbean countries selected by non-probabilistic snowball sampling participated. A confirmatory factor analysis was performed and the alignment method was used to evaluate invariance. Additionally, a graded response model was used for the assessment of item characteristics. Results The results indicate that there is approximate measurement invariance of the COVID-SCORE-10 among the participating countries. Furthermore, IRT results suggest that the COVID-SCORE-10 measures with good psychometric ability a broad spectrum of the construct assessed, especially around average levels. Comparison of COVID-SCORE-10 scores indicated that participants from Cuba, Uruguay and El Salvador had the most positive perceptions of government actions to address the pandemic. Thus, the underlying construct of perception of government actions was equivalent in all countries. Conclusion The results show the importance of initially establishing the fundamental measurement properties and MI before inferring the cross-cultural universality of the construct to be measured. COVID|19 COVID19 COVID |19 19 COVID-|1 COVIDSCORE10 COVIDSCORE SCORE 10 (COVID-SCORE-10 1 578 nonprobabilistic non probabilistic participated Additionally characteristics COVID-SCORE-1 Furthermore assessed levels Cuba pandemic Thus crosscultural cross cultural measured COVID|1 COVID1 |1 COVID-| COVIDSCORE1 (COVID-SCORE-1 57 COVID-SCORE- COVID| | COVID- (COVID-SCORE- 5 COVID-SCORE (COVID-SCORE

https://doi.org/10.1186/s41155-023-00277-9

13.

Fatal sclerosing mesenteritis: a 7-year-old male autopsy case report mesenteritis 7yearold yearold 7 year old
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Celis Pinto, Juan Carlos

; Hernández Peláez, Lucía

; Mendoza Pacas, Guillermo

; Mayordomo Colunga, Juan

; Balbín, Milagros

; Pitiot, Ana

; Torres-Rivas, Héctor-Enrique

; Blanco Lorenzo, Verónica

Autopsy and Case Reports

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2023, Volume 13 elocation e2023434

Resumo: En | Texto: En | PDF: En

ABSTRACT Sclerosing Mesenteritis (SM) is a rare diagnosis, particularly in pediatric patients, and is typically non-fatal when appropriately treated. Although molecular and immunohistochemical alterations have been described, no pathognomonic signature has been identified for this entity. This report presents a case of a seven-year-old boy who suffered sudden cardiorespiratory arrest. Upon autopsy, he was found to have multicentric SM on the upper mesentery, which led to bowel wall thinning and abdominal bleeding with bacterial translocation. We performed comprehensive morphological, immunohistochemical, and molecular analyses. SM is an atypical disorder with diverse clinical manifestations, including a rare but potentially fatal course. Early diagnosis is critical, given its potential severity. To our knowledge, this is the first case report of pediatric mortality linked to SM. Our findings emphasize the importance of increased awareness and early detection of SM in pediatric patients. (SM patients nonfatal non treated described entity sevenyearold seven year old arrest autopsy mesentery translocation morphological analyses manifestations course critical severity knowledge

https://doi.org/10.4322/acr.2023.434

14.

Evaluation of the properties of WHODAS-12 measurements in individuals with Chagas disease in Brazil WHODAS12 WHODAS 12 WHODAS-1 WHODAS1 1 WHODAS-
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Tavares, Patrícia Aparecida

; Oliveira, Cláudia Di Lorenzo

; Ferreira, Ariela Mota

; Baldoni, Nayara Ragi

; Quintino, Nayara Dornela

; Haikal, Desiree Sant’Ana

; Bierrenbach, Ana Luiza

; Ribeiro, Antonio Luiz Pinho

; Sabino, Ester Cerdeira

; Cardoso, Clareci Silva

Revista do Instituto de Medicina Tropical de São Paulo

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2023, Volume 65 elocation e30

Resumo: En | Texto: En | PDF: En

ABSTRACT Numerous tests employed to predict cardiac and functional status are expensive and not widely accessible for a considerable number of patients, particularly those diagnosed with Chagas disease (CD) residing in remote and endemic regions. To date, there is no knowledge of studies that have validated instruments that address functionality in an expanded way, including the biopsychosocial factors in patients with CD. This study aims to evaluate the psychometric properties of the World Health Organization Disability Assessment Schedule (WHODAS 2.0), in its 12-item shortened version (WHODAS-12) when applied to patients with CD. This is a cross-sectional study of a prospective cohort that follows individuals with CD (SaMi-Trop). Data collection took place between October 2019 and March 2020. In the interviews, sociodemographic information, life habits, clinical information, and indicators of disability measured by WHODAS-12 were collected. Descriptive analysis, internal consistency and construct validity of the instrument were performed. A total of 628 patients with CD were interviewed, most were women (69.5%), their mean age was of 57 years, and most declared an average self-perception of health (43.4%). The 12 items of WHODAS-12 were distributed into three factors, which together account for 61% of the variance. The Kaiser–Meyer–Olkin (KMO) index was 0.90, indicating adequacy of the sample for factor analysis. The internal consistency of the global scale showed alpha = 0.87. The percentage of incapacity was 16.05%, indicating mild incapacity for the evaluated patients. WHODAS-12 is a valid and reliable measure to assess the disability of the Brazilian population with CD. (CD regions date way WHODAS 2.0, 20 2.0 , 2 0 2.0) 12item item WHODAS12 (WHODAS-12 crosssectional cross sectional SaMiTrop. SaMiTrop SaMi Trop . (SaMi-Trop) 201 2020 interviews information habits WHODAS-1 collected analysis performed 62 interviewed 69.5%, 695 69.5% 69 5 (69.5%) years selfperception self perception 43.4%. 434 43.4% 43 4 (43.4%) 1 61 variance KaiserMeyerOlkin Kaiser Meyer Olkin KMO (KMO 090 90 0.90 087 87 0.87 1605 16 05 16.05% 2. WHODAS1 (WHODAS-1 (SaMi-Trop 202 WHODAS- 6 69.5 (69.5% 43.4 (43.4% 09 9 0.9 08 8 0.8 160 16.05 (WHODAS- 69. (69.5 43. (43.4 0. 16.0 (69. (43. 16. (69 (43 (6 (4 (

https://doi.org/10.1590/s1678-9946202365030

15.

Enfermedad de Alzheimer. Evidencia actual sobre el papel preventivo de la nutrición
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Lorenzo-Mora, Ana María

; Lozano-Estevan, María del Carmen

; Ghazi, Yalda

; González-Rodríguez, Liliana G

Nutrición Hospitalaria

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2023, Volume 40 Nº spe2 Páginas 41 - 45

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Introducción: en las últimas décadas, se ha observado un incremento significativo en la incidencia de la enfermedad de Alzheimer (EA). En la actualidad, no se dispone de tratamientos farmacológicos efectivos, lo que hace que las medidas preventivas sean particularmente importantes. Objetivo: analizar la evidencia científica disponible sobre factores nutricionales y dietéticos y su asociación con la prevención de la EA. Métodos: se llevó a cabo una revisión de la literatura científica sobre factores nutricionales y dietéticos relacionados con la prevención de la EA. Resultados: diversos componentes de la dieta se han asociado positivamente con la prevención de la EA. Estos incluyen hidratos de carbono complejos, fibra, omega-3, proteínas de origen vegetal, vitaminas (folatos, colina, vitamina D, C, B6 y B9), zinc y algunos compuestos bioactivos como los flavonoles, y los probióticos. El seguimiento de las dietas mediterránea, Dietary Approaches to Stop Hypertension (DASH) y Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) se ha asociado con un menor de riesgo de desarrollar la enfermedad. Conclusión: la nutrición podría tener un papel protector frente a la EA, aunque se requieren más estudios al respecto.

Abstract Introduction: in the last decades, a significant increase in the incidence of Alzheimer's disease (AD) has been observed. Currently, there are no effective pharmacological treatments available, which makes preventive measures particularly important. Objective: to analyze the available scientific evidence on nutritional and dietary factors and their association with AD prevention. Methods: a review of nutritional and dietary factors related to the prevention of AD was conducted. Results: several dietary components have been positively associated with AD prevention, including intake of complex carbohydrates, fiber, omega-3, plant-based proteins, vitamins (folates, choline, vitamin D, C, B6 and B9), zinc, some bioactive compounds such as flavonols and probiotics. Following the Mediterranean, Dietary Approaches to Stop Hypertension (DASH) y Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diets has been associated with a lower risk of developing the disease. Conclusion: nutrition may have a protective role against AD, although further studies are needed in this regard.

https://doi.org/10.20960/nh.04954

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