In this study, the typical azo dye methyl orange (MO) was degraded by pyrite (FeS2) activated by hydrogen peroxide (H2O2). When [MO] = 0.1 mM, [FeSJ = 2.0 g/L and [H2O2] = 22 mM, 96.4% MO was removed in 120 min and the TOC removal rate was higher than 50%. HO* was the primary radical responsible for MO degradation, in addition, the acid condition promoted the degradation of MO in the FeS2/H2O2 system. MO in tap water and river water was not effectively degraded, whereas acidification could weaken the inhibitory effect on the FeS2/ H2O2 system to enable the degradation of MO in tap and river water. The OD600 indicated that the solution was environmentally friendly after the reaction, and three degradation pathways of MO were discussed. In summary, Fe(ll) could be dissolved from FeS2, which activated H2O2 to generate Fe(lll) and HO*. FeS2 could reduce Fe(lll) into Fe(ll), thus realizing the Fe(lll)/(ll) cycle and efficiently activating H2O2 to degrade MO.

Double-layer Ni-P coatings with low phosphorus content in the inner layer and high phosphorus content in the outer layer and Ni-Mo-P composite coatings are successfully prepared on the surface of AZ91D magnesium alloy by chemical plating process. The microstructures, friction and corrosion resistance of double-layer Ni-P and Ni-Mo-P coatings are studied in comparison. Meanwhile, the deposition and corrosion resistance mechanism for the coatings are investigated. Results convey that both Ni-P and Ni-Mo-P coatings showcase an amorphous structure. The coating possesses denser and more homogeneous structure with the co-doping of Mo. The micro-indentation hardness (859.7 HV) and friction coefficient (0.58) of Ni-Mo-P coatings show that the ternary alloy coating is firmly bonded to the magnesium alloy substrate. Besides, the Ni-Mo-P coatings demonstrate exceptional wear resistance attributed to Mo co-deposition, fostering grain refinement and facilitating the growth of passivation films. Doublelayer Double NiP Ni P NiMoP AZD AZ D process microstructures doublelayer double comparison Meanwhile investigated codoping co doping microindentation micro indentation 859.7 8597 859 7 (859. HV 0.58 058 0 58 (0.58 substrate Besides codeposition, codeposition deposition, co-deposition films 859. 85 (859 0.5 05 5 (0.5 8 (85 0. (0. (8 (0 (

Abstract Introduction: dysphagia is a common complication of stroke, and serum albumin is widely recognized as a strong prognostic marker of health and/or disease status. However, the correlation between dysphagia and serum albumin levels has not been established. Objectives: to observe the correlation between dysphagia and serum albumin levels and prognosis in patients with stroke. Methods: we performed a retrospective study of patients hospitalized between June 1, 2018, and June 1, 2022. A total of 1,370 patients were enrolled. The patients were divided into two groups: dysphagia and non-dysphagia. Binary logistic regression and multiple linear regression models were used to analyze the correlation between dysphagia, albumin, modified Rankin Scale (mRS), activities of daily living (ADL), and length of hospital stay (LOS). Results: after adjusting for confounding factors, the risk of pneumonia in the dysphagia group was 2.417 times higher than that in the non-dysphagia group (OR = 2.417, 95 % CI: 1.902-3.072, p = 0.000). The risk of mRS ≥ 3 and modified Barthel index (MBI) < 60 in patients with dysphagia was 3.272-fold (OR = 3.272, 95 % CI: 2.508-4.269, p < 0.001) and 1.670-fold (OR = 1.670, 95 % CI: 1.230-2.268, p < 0.001), respectively; and the risk of hypoproteinemia was 2.533 times higher (OR = 2.533, 95 % CI: 1.879-3.414, p = 0.000). Stepwise linear regression showed that dysphagia was significantly correlated with lower albumin levels and higher mRS, lower ADL, and longer LOS in patients with stroke (β = -0.220, β = 0.265, β = -0.210, and β = 0.147, respectively; p < 0.001). Conclusions: dysphagia in patients with stroke is associated with decreased albumin levels and has an impact on its prognosis.

Resumen Introducción: la disfagia es una complicación común del accidente cerebrovascular, y la albúmina sérica es ampliamente reconocida como un fuerte marcador pronóstico del estado de salud y/o enfermedad. Sin embargo, no se ha establecido la correlación entre la disfagia y los niveles de albúmina sérica. Objetivos: observar la correlación entre la disfagia y los niveles de albúmina sérica y el pronóstico en pacientes con accidente cerebrovascular. Métodos: realizamos un estudio retrospectivo de pacientes hospitalizados entre el 1 de junio de 2018 y el 1 de junio de 2022. Se inscribieron un total de 1.370 pacientes, los cuales fueron divididos en dos grupos: con disfagia y sin disfagia. Se utilizaron modelos de regresión logística binaria y de regresión lineal múltiple para analizar la correlación entre la disfagia, la albúmina, la escala de Rankin modificada (ERm), las actividades de la vida diaria (AVD) y el tiempo de estancia hospitalaria (TEH). Resultados: después de ajustar por factores de confusión, el riesgo de neumonía en el grupo de disfagia fue 2,417 veces mayor que en el grupo sin disfagia (OR = 2,417, IC 95 %: 1,902-3,072, p = 0,000). El riesgo de ERm ≥ 3 y el índice de Barthel modificado (MBI) < 60 en pacientes con disfagia se multiplicó por 3,272 veces (OR = 3,272, IC 95 %: 2,508-4,269, p < 0,001) y 1,670 veces (OR = 1,670, IC 95 %: 1,230-2,268, p < 0,001), respectivamente; el riesgo de hipoproteinemia fue 2,533 veces mayor (OR = 2,533, IC 95 %: 1,879-3,414, p = 0,000). La regresión lineal por pasos mostró que la disfagia se correlacionó significativamente con niveles más bajos de albúmina y ERm más altos, AVD más bajos y TEH más prolongados en pacientes con accidente cerebrovascular (β = -0,220, β = 0,265, β = -0,210 y β = 0,147, respectivamente; p < 0,001). Conclusiones: la disfagia en pacientes con accidente cerebrovascular se asocia a una disminución de los niveles de albúmina y repercute en su pronóstico.

Designing highly efficient dialkylphosphinic acid extractant for zirconium/hafnium separation relies on systematic structure-property studies. In this paper, dialkylphosphinic acids with different substituents at β-C, γ-C and δ-C for zirconium and hafnium extraction and separation from H2SO4 media were investigated. The results show that substituents at β-C, γ-C and δ-C reduce the extraction ability of dialkylphosphinic acids for both zirconium and hafnium. The substituent effect at β-C is greater than that at γ-C and δ-C. The larger steric hindrance of the substituents (ethyl > methyl > H), the weaker extraction ability of the dialkylphosphinic acids. The zirconium and hafnium separation behavior is related to the extraction ability of dialkylphosphinic acids. Dialkylphosphinic acids with stronger extraction ability show better zirconium/hafnium separation performance at higher acidity of 2.0 mol L-1 H2SO4, while those with weaker extraction ability show better zirconium and hafnium separation performance at lower acidity of 0.25 mol L-1 H2SO4. The highest hafnium/zirconium separation factor (βHf/Zr) in the current study occurs with (2-ethylhexyl)(2,4,4-trimethylpentyl)phosphinic acid (USTB-1), which reaches 19.2. zirconiumhafnium structureproperty structure property studies paper βC, βC β C, C γC γ δC δ HSO H SO H2SO investigated δC. C. ethyl H, , H) 20 2 0 2. L1 L 1 L- 025 25 0.2 hafniumzirconium βHf/Zr βHfZr βHf Zr (βHf/Zr 2ethylhexyl2,4,4trimethylpentylphosphinic 2ethylhexyl244trimethylpentylphosphinic ethylhexyltrimethylpentylphosphinic ethylhexyl 2,4,4 trimethylpentyl phosphinic 4 USTB1, USTB1 USTB (USTB-1) 192 19 19.2 02 0. 2ethylhexyl2 4trimethylpentylphosphinic trimethylpentylphosphinic 244 2,4, (USTB-1 19. 2ethylhexyl 24 2,4 (USTB- 2, (USTB

Resumen Objetivo: realizar una revisión sistemática de los estudios observacionales que analizan la asociación entre la ingesta de alimentos ultraprocesados (UPF) y el riesgo de depresión. Material y métodos: la búsqueda se adhirió a las directrices Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA); se realizó una búsqueda de estudios observacionales publicados hasta junio de 2020 en las bases de datos PubMed, Embase, Cochrane Library y Web of Science, seguida de búsquedas manuales adicionales. Ocho revisores, que trabajaron de forma independiente en equipos de dos, seleccionaron los estudios para su elegibilidad, extrajeron los datos y evaluaron el riesgo de sesgo. Los desacuerdos se resolvieron a través de la discusión o, si era necesario, a través de la adjudicación de un tercero. Se evaluaron los estudios transversales mediante la lista de comprobación metodológica de la Agency for Healthcare Research and Quality (AHRQ) y los estudios de cohortes y de casos y controles mediante la escala Newcastle-Ottawa (NOS) para la calidad. Se utilizó un formato tabular para resumir los artículos. Resultados: finalmente se seleccionaron 28 estudios que evaluaban la ingesta de UPF y el riesgo de depresión, 21 de los cuales tenían un diseño transversal, 6 un diseño de cohortes y 1 un diseño de casos y controles. De ellos, 4 estudios de cohortes y 17 estudios transversales encontraron que el consumo de UPF se asociaba positivamente con la depresión o los síntomas depresivos. Conclusiones: nuestra revisión demostró que la mayoría de los estudios incluidos en la revisión sistemática mostraron que el consumo de UPF está asociado con el riesgo de depresión. Los estudios futuros deberían considerar el uso de evaluaciones validadas del consumo de alimentos y métodos estandarizados de evaluación de la depresión para promover la comparabilidad entre los estudios.

Abstract Objective: to conduct a systematic review of the observational studies analyzing the association between ultra-processed food (UPF) intake and the risk of depression. Material and methods: the search adhered to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA); a search for observational studies published until June 2020 was performed in PubMed, Embase, Cochrane Library, and Web of Science databases, followed by additional manual searches. Eight reviewers, working independently in teams of two, screened studies for eligibility, extracted data, and assessed risk of bias. We resolved disagreements through discussion or, if necessary, through adjudication by a third (LH). And the study assessed cross-sectional studies using the Agency for Healthcare Research and Quality (AHRQ) methodological checklist and cohort and case-control studies using the Newcastle-Ottawa Scale (NOS) for quality. We used a tabular format to summarize the articles. Results: twenty-eight studies evaluating UPF intake and risk of depression were finally selected, 21 of which had a cross-sectional design, 6 studies had a cohort design, and 1 had a case-control design. Of these, 4 cohort studies and 17 cross-sectional studies found that consumption of UPF were positively associated with depression or depressive symptoms. Conclusions: our review demonstrated that most studies included in the systematic review showed that UPF consumption is associated with the risk of depression. Future studies should consider the use of validated food intake assessments and standardized depression assessment methods to promote comparability between studies.

ABSTRACT Introduction: Lower body perfusion (LBP) is a technique used to provide blood perfusion to distal organs and spinal cord during circulatory arrest. However, the effect of LBP on the prognosis of aortic arch surgery, especially on postoperative renal function, remains unclear. Methods: A total of 304 patients with acute type A aortic dissection who underwent total aortic arch replacement combined with frozen elephant trunk implantation between May 2016 and December 2021 were retrospectively analyzed. The patients were divided into LBP group (group L, n=85) and non-LBP group (group NL, n=219). Routine lower body circulatory arrest was applied during operation in group NL, and antegrade LBP combined was applied during operation in group L. Perioperative data were recorded. Propensity score matching was used for statistical analysis. Results: After propensity score matching, 85 pairs of patients were successfully matched. Two groups significantly differed in circulatory arrest time (six minutes vs. 30 minutes, P=0.000), cross-clamping time (101 minutes vs. 92 minutes, P=0.010), minimum nasopharyngeal temperature (29.4ºC vs. 27.2ºC, P=0.000), and highest lactate value during cardiopulmonary bypass (2.3 μmol/L vs. 4.1 μmol/L, P=0.000). Considering the postoperative indicators, the drainage volume (450 mL vs. 775 mL, P=0.000) and the incidence of level I acute kidney injury (23.5% vs. 32%, P=0.046) in group L was lower than those in group NL. Conclusion: LBP resulted as a safe and feasible approach in aortic arch surgery, as it could significantly shorten the circulatory arrest time, which might reduce the incidence of postoperative level I acute kidney injury. Introduction (LBP However surgery function unclear Methods 201 202 analyzed n=85 n85 n nonLBP non NL n=219. n219 n=219 . 219 n=219) recorded analysis Results 8 matched six vs 3 P=0.000, P0000 P P=0.000 , 0 000 crossclamping cross clamping 101 (10 9 P=0.010, P0010 P=0.010 010 P=0.010) 29.4ºC 294ºC ºC 29 4ºC 272ºC 27 2ºC 27.2ºC 2.3 23 2 (2. μmolL μmol 41 4 1 4. P=0.000. indicators 450 (45 77 23.5% 235 5 (23.5 32 32% P=0.046 P0046 046 Conclusion 20 n=8 n8 n21 n=21 21 P000 P=0.00 00 10 (1 P001 P=0.01 01 2. (2 45 (4 7 23.5 (23. P=0.04 P004 04 n= n2 n=2 P00 P=0.0 ( 23. (23 P0 P=0. P=0 P=

RESUMEN Introducción: Entre los beneficios conocidos de la gimnasia aeróbica están la flexibilidad, mejora de la coordinación motora, pérdida de peso, y el progreso en el equilibrio. La capacidad de equilibrio es muy importante para los alumnos de aeróbic y se cree que la introducción de un protocolo complementario puede aportar más beneficios en el rendimiento de sus practicantes. Objetivo: Explorar los efectos del entrenamiento del equilibrio en estudiantes universitarios que practican aeróbic. Métodos: Se realizó un experimento de 9 semanas en el que participaron 100 estudiantes universitarios de aeróbic, los voluntarios se dividieron en dos grupos sin diferencias estadísticas. Se añadió entrenamiento de equilibrio al grupo experimental, mientras que el grupo de control permaneció con la práctica docente diaria. Resultados: La puntuación de la flexión de brazos aumentó de 2,27±0,45 a 2,73±0,46, la puntuación de la rotación corporal fue de 1,87±0,35 a 2,40±0,51, y la puntuación de la sentadilla fue de 2,53±0,52 a 3,03±0,30. Mientras que la capacidad aeróbica de los estudiantes universitarios del grupo experimental mejoró eficazmente, no se observaron cambios significativos en los datos del grupo de control. Conclusión: El entrenamiento del equilibrio puede mejorar eficazmente la capacidad de los estudiantes universitarios, lo que conduce a la mejora del proceso de enseñanza del aeróbic para estudiantes universitarios. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento. Introducción flexibilidad motora peso practicantes Objetivo Métodos 10 estadísticas diaria Resultados 227045 2 27 0 45 2,27±0,4 273046 73 46 2,73±0,46 187035 1 87 35 1,87±0,3 240051 40 51 2,40±0,51 253052 53 52 2,53±0,5 303030 3 03 30 3,03±0,30 Conclusión II tratamiento 22704 4 2,27±0, 27304 7 2,73±0,4 18703 8 1,87±0, 24005 5 2,40±0,5 25305 2,53±0, 30303 3,03±0,3 2270 2,27±0 2730 2,73±0, 1870 1,87±0 2400 2,40±0, 2530 2,53±0 3030 3,03±0, 227 2,27± 273 2,73±0 187 1,87± 240 2,40±0 253 2,53± 303 3,03±0 22 2,27 2,73± 18 1,87 24 2,40± 25 2,53 3,03± 2,2 2,73 1,8 2,40 2,5 3,03 2, 2,7 1, 2,4 3,0 3,

ABSTRACT Introduction: Among the known benefits of aerobics gymnastics are flexibility, motor coordination improvement, weight loss, and balance improvement. The balance capacity is very important for aerobics students, and it is believed that introducing a complementary protocol can bring greater benefits to the performance of its practitioners. Objective: Explore the effects of balance training on university students practicing aerobics. Methods: A 9-week experiment was conducted employing 100 college aerobics students. The volunteers were divided into two groups without statistical differences. Balance training was added to the experimental group, while the control group remained with daily teaching practice. Results: The push-up score increased from 2.27±0.45 to 2.73±0.46, the body rotation score was from 1.87±0.35 to 2.40±0.51, and the squat score was from 2.53±0.52 to 3.03±0.30. While the aerobic ability of college students in the experimental group was effectively improved, no significant changes were observed in the control group data. Conclusion: Balance training can effectively improve college students’ ability, leading to improvement in teaching aerobics to college students. Level of evidence II; Therapeutic studies - investigation of treatment outcomes. Introduction flexibility loss practitioners Objective Methods 9week week 9 10 differences practice Results pushup push up 227045 2 27 0 45 2.27±0.4 273046 73 46 2.73±0.46 187035 1 87 35 1.87±0.3 240051 40 51 2.40±0.51 253052 53 52 2.53±0.5 303030 3 03 30 3.03±0.30 improved data Conclusion II outcomes 22704 4 2.27±0. 27304 7 2.73±0.4 18703 8 1.87±0. 24005 5 2.40±0.5 25305 2.53±0. 30303 3.03±0.3 2270 2.27±0 2730 2.73±0. 1870 1.87±0 2400 2.40±0. 2530 2.53±0 3030 3.03±0. 227 2.27± 273 2.73±0 187 1.87± 240 2.40±0 253 2.53± 303 3.03±0 22 2.27 2.73± 18 1.87 24 2.40± 25 2.53 3.03± 2.2 2.73 1.8 2.40 2.5 3.03 2. 2.7 1. 2.4 3.0 3.

RESUMO Introdução: Entre os benefícios da ginástica aeróbica conhecidos estão a flexibilidade, aprimoramento da coordenação motora, perda de peso, e a melhora no equilíbrio. A capacidade de equilíbrio é muito importante para os estudantes de aeróbica e acredita-se que a introdução de um protocolo complementar possa trazer maiores benefícios no desempenho de seus praticantes. Objetivo: Explorar os efeitos do treinamento de equilíbrio em estudantes universitários praticantes de aeróbica. Métodos: Uma experiência de 9 semanas foi realizada empregando 100 estudantes universitários de aeróbica, os voluntários foram divididos em dois grupos sem diferenças estatísticas. Ao grupo experimental foi adicionado um treino de equilíbrio, enquanto o grupo de controle permaneceu com a prática de ensino cotidiana. Resultados: A pontuação no push-up elevou-se de 2,27±0.45 para 2,73±0,46, a pontuação da rotação corporal foi de 1,87±0,35 para 2,40±0,51, e a pontuação em agachamento foi de 2,53±0,52 para 3,03±0,30. Enquanto a habilidade aeróbica dos estudantes universitários no grupo experimental foi efetivamente aperfeiçoada, não foram observadas alterações significativas nos dados do grupo de controle. Conclusão: O treinamento de equilíbrio pode efetivamente melhorar a habilidade dos estudantes universitários, conduzindo à melhoria do processo de ensino de aeróbica para universitários. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento. Introdução flexibilidade motora peso acreditase acredita se Objetivo Métodos 10 estatísticas cotidiana Resultados pushup push up elevouse elevou 227045 2 27 0 45 2,27±0.4 273046 73 46 2,73±0,46 187035 1 87 35 1,87±0,3 240051 40 51 2,40±0,51 253052 53 52 2,53±0,5 303030 3 03 30 3,03±0,30 aperfeiçoada Conclusão II tratamento 22704 4 2,27±0. 27304 7 2,73±0,4 18703 8 1,87±0, 24005 5 2,40±0,5 25305 2,53±0, 30303 3,03±0,3 2270 2,27±0 2730 2,73±0, 1870 1,87±0 2400 2,40±0, 2530 2,53±0 3030 3,03±0, 227 2,27± 273 2,73±0 187 1,87± 240 2,40±0 253 2,53± 303 3,03±0 22 2,27 2,73± 18 1,87 24 2,40± 25 2,53 3,03± 2,2 2,73 1,8 2,40 2,5 3,03 2, 2,7 1, 2,4 3,0 3,

Abstract Objectives The deposition of monosodium urate (MSU) crystals within synovial joints and tissues is the initiating factor for gout arthritis. Thus, MSU crystals are a vital tool for studying gout's molecular mechanism in animal and cellular models. This study mainly compared the excellence and worseness of MSU crystals prepared by different processes and the degree of inflammation induced by MSU crystals. Methods MSU crystals were prepared using neutralization, alkali titration, and acid titration methods. The crystals' shape, length, quality, and uniformity were observed by polarized light microscopy and calculated by the software Image J. The foot pad and air pouch models were used to assess the different degrees of inflammation induced by the MSU crystals prepared by the three different methods at different time points. Paw swelling was evaluated by caliper. In air pouch lavage fluid, inflammatory cell recruitment was measured by hemocytometer, and the level of IL-1β TNF- α, and IL-18 by ELISA. Inflammatory cell infiltration was assayed by immunohistochemistry of air pouch synovial slices. Results For the preparation of MSU crystals with the same uric acid, the quantity acquired by the alkalization method was highest, followed by neutralization, with the acid titration method being the lowest. The crystals prepared by neutralization were the longest. The swelling index of the foot pad induced by MSU crystals prepared by acid titration was significantly lower than that of the other methods at 24 h. The inflammatory cell recruitment and level of 1-1β, TNF-α, and IL-18 in air pouch lavage fluid were lowest in animals with crystals prepared by acid titration. IL-1β secretion induced by MSU crystals prepared by acid titration was significantly lower than that of the other two groups, but there was no significant difference in IL-18 secretion between the three groups in THP-1 macrophages and BMDMs. Conclusions All three methods can successfully prepare MSU crystals, but the levels of inflammation induced by the crystals prepared by the three methods were not identical. The degree of inflammation induced by MSU crystals prepared by neutralization and alkalization is greater than by acid titration, but the quantity of MSU crystals obtained by the alkalization method is higher and less time-consuming. Apparently, the window of inflammation triggered by acid titration preparation is shorter compared to other forms of crystal preparation. Overall, MSU crystals prepared by the alkaline method should be recommended for studying the molecular mechanisms of gout in animal and cellular models. (MSU arthritis Thus gouts s shape length quality J points caliper hemocytometer IL1β ILβ IL 1β β TNF α IL18 18 IL-1 ELISA slices highest longest 2 h 11β, 11β 1 1β, 1-1β TNFα, TNFα TNF-α THP1 THP THP- BMDMs identical timeconsuming. timeconsuming consuming. consuming time-consuming Apparently Overall IL1 IL-

Abstract Objectives Cardiac involvement is one of the most serious complications of idiopathic inflammatory myopathy (IIM) that indicates poor prognosis. However, there is a lack of effective biomarkers for the identification of cardiac involvement and the prediction of prognosis in IIM. Here, we aimed to explore the value of different cardiac biomarkers in IIM patients. Methods A total of 142 IIM patients in the Department of Rheumatology and Immunology, Ruijin Hospital from July 2019 to October 2022 were included in this study. The clinical characteristics, laboratory tests, treatments and prognosis were recorded. The disease activity was assessed according to the core set measures. The correlations of the serum cardiac biomarkers levels with disease activity were analyzed by the Spearman correlation test. Risk factors for cardiac involvement were evaluated by multivariate logistic regression analysis. Results Higher high-sensitivity cardiac troponin I (hs-cTnI) levels were associated with cardiac involvement (n = 41) in IIM patients [adjusted OR 7.810 (95% CI: 1.962–31.097); p = 0.004], independent of other serum cardiac biomarkers. The abnormal hs-cTnI had the highest AUC for distinguishing of cardiac involvement in IIM patients (AUC = 0.848, 95% CI: 0.772,0.924; p < 0.001). Besides, we found that high serum levels of hs-cTnI were significantly correlated with disease activity. Moreover, patients with higher serum levels of hs-cTnI tended to suffer from poor prognosis. Conclusions Serum hs-cTnI testing may play a role in screening for cardiac involvement in IIM patients. Abnormal levels of serum hs-cTnI were associated with increased disease activity and poor prognosis. Key Points Among all the cardiac biomarkers, the serum levels of hs-cTnI were independently associated with cardiac involvement in IIM patients. The serum levels of hs-cTnI were significantly correlated with disease activity in IIM patients. The abnormal hs-cTnI levels were correlated with poor prognosis in IIM patients. (IIM However Here 14 Immunology 201 202 study characteristics tests recorded measures test analysis highsensitivity sensitivity hscTnI hs cTnI (hs-cTnI n 41 adjusted 7810 7 810 7.81 95 (95 CI 1.962–31.097 196231097 1 962 31 097 1.962–31.097) 0.004, 0004 0.004 , 0 004 0.004] 0848 848 0.848 0.772,0.924 07720924 772 924 0.001. 0001 0.001 . 001 0.001) Besides Moreover 20 4 781 81 7.8 9 (9 1.962–31.09 19623109 96 3 09 000 0.00 00 084 84 0.84 0.772,0.92 0772092 77 92 2 78 8 7. ( 1.962–31.0 1962310 0.0 08 0.8 0.772,0.9 077209 1.962–31. 196231 0. 0.772,0. 07720 1.962–31 19623 0.772,0 0772 1.962–3 1962 0.772, 077 1.962– 196 0.772 07 1.962 19 0.77 1.96 0.7 1.9 1.

RESUMO Objetivo: Investigar a eficácia da medicina tradicional chinesa (MTC) no tratamento da incontinência urinária de esforço (IUE) feminina. Método: Foram realizadas pesquisas de artigos publicados até setembro de 2022 nas bases de dados PubMed, Cochrane, Web of Science, Embase, CNKI, Wanfang e VIP. As variáveis foram analisadas por meio da diferença de média ponderada (DMP), da diferença média padronizada (DMP), da razão de chances (RC) e do intervalo de confiança (IC) de 95%. Resultados: Esta pesquisa envolveu oito estudos, contando com a participação de 744 pacientes. Os resultados indicam que a terapia da medicina tradicional chinesa (MTC) apresentou melhorias significativas nos resultados clínicos de pacientes com incontinência urinária de esforço (IUE) (RM = 2.90, IC de 95%: 1.92–4.37, P = 0.000), ao reduzir a pontuação do Questionário Internacional sobre a Incontinência Urinária – Versão Breve (ICIQ-SF) (Diferença de Média Ponderada = –2.41, IC de 95%: –2.83– –1.98, P = 0.000), assim como na diminuição do volume de urina na 1 hora de vazamento do absorvente urinário (Diferença de Média Ponderada = –1.86, IC de 95%: –2.23– –1.49, P = 0.000) e no aumento da pressão máxima de encerramento uretral (PMCU) (Diferença Média Padronizada = 0.86, IC de 95%: 0.61–1.11, P = 0.000). Conclusão: A terapia da medicina tradicional chinesa (MTC) é eficaz na melhoria dos sintomas da incontinência urinária, na urodinâmica e na qualidade de vida em pacientes com incontinência urinária de esforço (IUE). Este artigo fornece uma referência para a aplicação da terapia da MTC em mulheres com incontinência urinária. Objetivo (MTC IUE (IUE feminina Método 202 PubMed Cochrane Science Embase CNKI VIP DMP, DMP , (DMP) RC (RC (IC 95 95% Resultados estudos 74 RM 290 2 90 2.90 192437 92 4 37 1.92–4.37 0.000, 0000 0.000 0 000 ICIQSF ICIQ SF (ICIQ-SF Diferença 241 41 –2.41 283 83 –2.83 198 98 –1.98 186 86 –1.86 223 23 –2.23 149 49 –1.49 PMCU (PMCU 086 0.86 061111 61 11 0.61–1.11 0.000. . Conclusão IUE. 20 (DMP 9 7 29 2.9 19243 3 1.92–4.3 0.00 00 24 –2.4 28 8 –2.8 19 –1.9 18 –1.8 22 –2.2 14 –1.4 08 0.8 06111 6 0.61–1.1 2. 1924 1.92–4. 0.0 –2. –1. 0. 0611 0.61–1. 192 1.92–4 –2 –1 061 0.61–1 1.92– 06 0.61– 1.92 0.61 1.9 0.6 1.

ABSTRACT Objectives: To investigate the efficacy of traditional Chinese medicine (TCM) in the treatment of female stress urinary incontinence (SUI). Method: PubMed, Cochrane, Web of Science, Embase, CNKI, Wanfang, and VIP databases were searched for articles published up to September 2022. Variables were analyzed using weighted mean difference (WMD), standardized mean difference (SMD), odds ratios (OR), and 95% confidence interval (CI). Results: Eight studies containing 744 patients were included in this study. The results demonstrate that TCM therapy had more advantages in improving the clinical outcome of SUI patients (OR = 2.90, 95%CI:1.92–4.37, P = 0.000), reducing the International Consultation on Incontinence Questionnaire Short-Form (ICIQ-SF) score (WMD = –2.41, 95%CI:–2.83– –1.98, P = 0.000), reducing 1-h urinary pad leakage urine volume (WMD = –1.86, 95%CI:–2.23– –1.49, P = 0.000) and increasing Maximum urethral closure pressure (MUCP) (SMD = 0.86, 95%CI: 0.61–1.11, P = 0.000). Conclusion: TCM therapy is effective in improving urinary incontinence symptoms, urodynamics, and quality of life in patients with SUI. This article provides a reference for the application of TCM therapy in women with urinary incontinence. Objectives (TCM . (SUI) Method PubMed Cochrane Science Embase CNKI Wanfang 2022 WMD, WMD , (WMD) SMD, SMD (SMD) OR, OR (OR) 95 CI. CI (CI) Results 74 study 290 2 90 2.90 95%CI1.92–4.37, 95CI192437 95%CI 1.92–4.37, 1 92 4 37 95%CI:1.92–4.37 0.000, 0000 0.000 0 000 ShortForm Short Form ICIQSF ICIQ SF (ICIQ-SF 241 41 –2.41 95%CI–2.83– 95CI283 –2.83– 83 95%CI:–2.83 198 98 –1.98 1h h 186 86 –1.86 95%CI–2.23– 95CI223 –2.23– 23 95%CI:–2.23 149 49 –1.49 MUCP (MUCP 086 0.86 95CI 061111 61 11 0.61–1.11 0.000. Conclusion symptoms urodynamics (SUI 202 9 (CI 7 29 2.9 CI1 95%CI1.92–4.37 95CI19243 192437 1.92–4.37 3 95%CI:1.92–4.3 0.00 00 24 –2.4 95%CI–2.83 95CI28 283 –2.83 8 95%CI:–2.8 19 –1.9 18 –1.8 95%CI–2.23 95CI22 223 –2.23 95%CI:–2.2 14 –1.4 08 0.8 06111 6 0.61–1.1 20 2. 95%CI1.92–4.3 95CI1924 19243 1.92–4.3 95%CI:1.92–4. 0.0 –2. 95%CI–2.8 95CI2 28 –2.8 95%CI:–2. –1. 95%CI–2.2 22 –2.2 0. 0611 0.61–1. 95%CI1.92–4. 95CI192 1924 1.92–4. 95%CI:1.92–4 –2 95%CI–2. 95%CI:–2 –1 061 0.61–1 95%CI1.92–4 95CI19 192 1.92–4 95%CI:1.92– – 95%CI–2 95%CI:– 06 0.61– 95%CI1.92– 95CI1 1.92– 95%CI:1.92 95%CI– 0.61 95%CI1.92 1.92 95%CI:1.9 0.6 95%CI1.9 1.9 95%CI:1. 95%CI1. 1. 95%CI:1 95%CI1

RESUMEN Objetivo: Investigar la eficacia de la medicina tradicional china (MTC) en el tratamiento de la incontinencia urinaria de esfuerzo (IUE) femenina. Método: Se llevaron a cabo búsquedas de artículos publicados hasta septiembre de 2022 en las bases de datos PubMed, Cochrane, Web of Science, Embase, CNKI, Wanfang y VIP. Las variables se analizaron mediante la diferencia de medias ponderada (DMP), la diferencia de medias estandarizada (DME), la razón de momios (RM) y el intervalo de confianza (IC) del 95%. Resultados: Este estudio incluyó ocho investigaciones con la participación de 744 pacientes. Los resultados indican que la terapia de medicina tradicional china (MTC) presentó mejoras significativas en los resultados clínicos de pacientes con incontinencia urinaria de esfuerzo (IUE) (RM = 2.90, IC del 95%: 1.92–4.37, P = 0.000), al reducir la puntuación del Cuestionario Internacional sobre la Incontinencia y su impacto en la calidad de vida (ICIQ-SF) (DMP = –2.41, IC del 95%: –2.83– –1.98, P = 0.000), así como la disminución del volumen de orina a la 1 hora de fuga de la almohadilla urinaria (DMP = –1.86, IC del 95%: –2.23– –1.49, P = 0.000) y el aumento de la presión de cierre uretral máxima (PCUM) (DME = 0.86, IC del 95%: 0.61–1.11, P = 0.000). Conclusión: La terapia de medicina tradicional china (MTC) resulta efectiva en la mejora de los síntomas de la incontinencia urinaria, la urodinámica y la calidad de vida en pacientes con incontinencia urinaria de esfuerzo (IUE). Este artículo ofrece una referencia para la aplicación de la terapia de MTC en mujeres con incontinencia urinaria. Objetivo (MTC IUE (IUE femenina Método 202 PubMed Cochrane Science Embase CNKI VIP DMP, DMP , (DMP) DME, DME (DME) RM (IC 95 95% Resultados 74 290 2 90 2.90 192437 92 4 37 1.92–4.37 0.000, 0000 0.000 0 000 ICIQSF ICIQ SF (ICIQ-SF 241 41 –2.41 283 83 –2.83 198 98 –1.98 186 86 –1.86 223 23 –2.23 149 49 –1.49 PCUM (PCUM 086 0.86 061111 61 11 0.61–1.11 0.000. . Conclusión IUE. 20 9 7 29 2.9 19243 3 1.92–4.3 0.00 00 24 –2.4 28 8 –2.8 19 –1.9 18 –1.8 22 –2.2 14 –1.4 08 0.8 06111 6 0.61–1.1 2. 1924 1.92–4. 0.0 –2. –1. 0. 0611 0.61–1. 192 1.92–4 –2 –1 061 0.61–1 1.92– – 06 0.61– 1.92 0.61 1.9 0.6 1.

RESUMEN Introducción: La enseñanza contemporánea en tenis de mesa carece de atención en habilidades globales, algunos estudios sugieren que el entrenamiento funcional puede suplir las demandas requeridas por el alto nivel de competición deportiva. Objetivo: Estudiar el efecto del entrenamiento funcional en la enseñanza del tenis de mesa en estudiantes universitarios. Métodos: Se realizó una selección aleatoria controlada (n=40), en la que el grupo experimental (n=20) eligió un programa de entrenamiento funcional, mientras que el grupo de control (n=20) participó en la enseñanza de las habilidades tradicionales del tenis de mesa. La frecuencia del entrenamiento fue de una hora diaria, tres veces por semana, con una duración de seis semanas. Se evaluó la forma física específica del tenis de mesa antes y después del experimento. Los datos se catalogaron y analizaron estadísticamente. Resultados: En el índice de habilidades manuales, la puntuación del grupo experimental aumentó de 63,194 a 79,683 puntos después del experimento, y la del grupo de control aumentó de 64,788 a 68,775 puntos después del experimento. En el índice de regresión, la puntuación del grupo experimental aumentó de 63,645 a 78,614, y la del grupo de control, de 64,152 a 70,574. Conclusión: El modo de entrenamiento funcional propuesto en este artículo puede mejorar rápidamente el nivel competitivo del tenis de mesa y mejorar el rendimiento competitivo de sus practicantes. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento. Introducción globales deportiva Objetivo universitarios Métodos n=40, n40 n n=40 , 40 (n=40) n=20 n20 20 (n=20 diaria semana semanas experimento estadísticamente Resultados manuales 63194 63 194 63,19 79683 79 683 79,68 64788 64 788 64,78 68775 68 775 68,77 regresión 63645 645 63,64 78614 78 614 78,614 64152 152 64,15 70574 70 574 70,574 Conclusión practicantes II tratamiento n4 n=4 4 (n=40 n=2 n2 2 (n=2 6319 6 19 63,1 7968 7 79,6 6478 64,7 6877 77 68,7 6364 63,6 7861 61 78,61 6415 15 64,1 7057 57 70,57 n= (n=4 (n= 631 1 63, 796 79, 647 64, 687 68, 636 786 78,6 641 705 5 70,5 (n 78, 70,

ABSTRACT Introduction: Contemporary table tennis teaching lacks attention to global abilities; some studies suggest that functional training can supply the demands of the high level of sport competition. Objective: Study the effect of functional training on teaching table tennis to college students. Methods: A controlled random selection was carried out (n=40), in which the experimental group (n=20) chose a functional training program. In contrast, the control group (n=20) participated in the teaching of traditional table tennis skills. The training frequency was one hour daily, three times a week, lasting six weeks. Table tennis-specific fitness was assessed before and after the experiment. Data were cataloged and statistically analyzed. Results: On the manual skills index, the experimental group's score increased from 63,194 to 79,683 points after the experiment, and the control group's score increased from 64,788 to 68,775 points after the experiment. In the regression index, the experimental group score increased from 63.645 to 78.614, and the control group score increased from 64.152 to 70.574. Conclusion: The functional training mode proposed in this paper can rapidly improve the competitive level of table tennis and improve the competitive performance of its practitioners. Level of evidence II; Therapeutic studies - investigation of treatment outcomes. Introduction abilities competition Objective students Methods n=40, n40 n n=40 , 40 (n=40) n=20 n20 20 (n=20 program contrast daily week weeks tennisspecific specific experiment analyzed Results index groups s 63194 63 194 63,19 79683 79 683 79,68 64788 64 788 64,78 68775 68 775 68,77 63645 645 63.64 78614 78 614 78.614 64152 152 64.15 70574 70 574 70.574 Conclusion practitioners II outcomes n4 n=4 4 (n=40 n=2 n2 2 (n=2 6319 6 19 63,1 7968 7 79,6 6478 64,7 6877 77 68,7 6364 63.6 7861 61 78.61 6415 15 64.1 7057 57 70.57 n= (n=4 (n= 631 1 63, 796 79, 647 64, 687 68, 636 63. 786 78.6 641 64. 705 5 70.5 (n 78. 70.

RESUMO Introdução: O ensino contemporâneo no tênis de mesa carece de atenção em habilidades globais, alguns estudos sugerem que o treinamento funcional possa suprir as demandas requisitadas pelo alto nível de competição esportiva. Objetivo: Estudar o efeito do treinamento funcional sobre o ensino do tênis de mesa nos estudantes universitários. Métodos: Foi realizada uma seleção randômica controlada (n=40), na qual o grupo experimental (n=20) escolheu um programa de treinamento funcional, enquanto o grupo de controle (n=20) participou do ensino das habilidades tradicionais do tênis de mesa. A frequência do treinamento foi de uma hora diária, três vezes por semana, com duração de seis semanas. A aptidão física específica do tênis de mesa foi avaliada antes e depois do experimento. Os dados foram catalogados e analisados estatisticamente. Resultados: No índice de habilidades manuais, a pontuação do grupo experimental aumentou de 63.194 para 79.683 pontos após o experimento, e a pontuação do grupo de controle aumentou de 64.788 para 68.775 pontos após o experimento. No índice de retrocesso, a pontuação do grupo experimental aumentou de 63.645 para 78.614, e a pontuação do grupo de controle aumentou de 64.152 para 70.574. Conclusão: O modo de treinamento funcional proposto neste artigo pode melhorar rapidamente o nível competitivo do tênis de mesa e melhorar o desempenho competitivo de seus praticantes. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento. Introdução globais esportiva Objetivo universitários Métodos n=40, n40 n n=40 , 40 (n=40) n=20 n20 20 (n=20 diária semana semanas experimento estatisticamente Resultados manuais 63194 63 194 63.19 79683 79 683 79.68 64788 64 788 64.78 68775 68 775 68.77 retrocesso 63645 645 63.64 78614 78 614 78.614 64152 152 64.15 70574 70 574 70.574 Conclusão praticantes II tratamento n4 n=4 4 (n=40 n=2 n2 2 (n=2 6319 6 19 63.1 7968 7 79.6 6478 64.7 6877 77 68.7 6364 63.6 7861 61 78.61 6415 15 64.1 7057 57 70.57 n= (n=4 (n= 631 1 63. 796 79. 647 64. 687 68. 636 786 78.6 641 705 5 70.5 (n 78. 70.

ABSTRACT Introduction: Lower body perfusion (LBP) is a technique used to provide blood perfusion to distal organs and spinal cord during circulatory arrest. However, the effect of LBP on the prognosis of aortic arch surgery, especially on postoperative renal function, remains unclear. Methods: A total of 304 patients with acute type A aortic dissection who underwent total aortic arch replacement combined with frozen elephant trunk implantation between May 2016 and December 2021 were retrospectively analyzed. The patients were divided into LBP group (group L, n=85) and non-LBP group (group NL, n=219). Routine lower body circulatory arrest was applied during operation in group NL, and antegrade LBP combined was applied during operation in group L. Perioperative data were recorded. Propensity score matching was used for statistical analysis. Results: After propensity score matching, 85 pairs of patients were successfully matched. Two groups significantly differed in circulatory arrest time (six minutes vs. 30 minutes, P=0.000), cross-clamping time (101 minutes vs. 92 minutes, P=0.010), minimum nasopharyngeal temperature (29.4ºC vs. 27.2ºC, P=0.000), and highest lactate value during cardiopulmonary bypass (2.3 μmol/L vs. 4.1 μmol/L, P=0.000). Considering the postoperative indicators, the drainage volume (450 mL vs. 775 mL, P=0.000) and the incidence of level I acute kidney injury (23.5% vs. 32%, P=0.046) in group L was lower than those in group NL. Conclusion: LBP resulted as a safe and feasible approach in aortic arch surgery, as it could significantly shorten the circulatory arrest time, which might reduce the incidence of postoperative level I acute kidney injury. Introduction (LBP However surgery function unclear Methods 201 202 analyzed n=85 n85 n nonLBP non NL n=219. n219 n=219 . 219 n=219) recorded analysis Results 8 matched six vs 3 P=0.000, P0000 P P=0.000 , 0 000 crossclamping cross clamping 101 (10 9 P=0.010, P0010 P=0.010 010 P=0.010) 29.4ºC 294ºC ºC 29 4ºC 272ºC 27 2ºC 27.2ºC 2.3 23 2 (2. μmolL μmol 41 4 1 4. P=0.000. indicators 450 (45 77 23.5% 235 5 (23.5 32 32% P=0.046 P0046 046 Conclusion 20 n=8 n8 n21 n=21 21 P000 P=0.00 00 10 (1 P001 P=0.01 01 2. (2 45 (4 7 23.5 (23. P=0.04 P004 04 n= n2 n=2 P00 P=0.0 ( 23. (23 P0 P=0. P=0 P=

RESUMEN Introducción: El extracto de cereza tiene una gran cantidad de antocianinas y flavonoides con efectos antioxidantes. Se ha demostrado que sus altas características antioxidantes reducen los marcadores de dolor muscular retardado (DOMS) y el daño muscular inducido por el ejercicio (EIMD) para mejorar la recuperación después del ejercicio. Objetivo: Verificar los efectos del extracto de cereza en el daño muscular posterior al ejercicio. Métodos: Se realizaron búsquedas sistemáticas en Google scholar, Medline y Scopus hasta febrero de 2022. Se aplicó la herramienta de colaboración Cochrane para determinar los riesgos de sesgo. Resultados: Los resultados mostraron que la administración de extracto de cereza no tuvo un impacto decreciente en los niveles de creatina quinasa en general: (WMD = 12,85 UI. L-1, IC del 95%: −35,94, 61,64; P = 0,606). Se observó una considerable heterogeneidad entre los artículos (prueba Q de Cochran = 990,80, P = 0,000, I2 = 96,7 %). Sin embargo, el consumo de extracto de cereza tiene un efecto significativo de reducción del dolor (WMD = −6,105 mm; IC del 95%: −11,193 −1,017; p = 0,019). Conclusión: El consumo de extracto de cereza fue eficaz para reducir el dolor muscular de aparición tardía entre los participantes en el análisis global y de subgrupos. Así, el extracto de cereza puede ser una alternativa complementaria en la recuperación después de los ejercicios. Nivel de evidencia II; Estudios terapéuticos - Revisión de manuscritos. Introducción DOMS (DOMS EIMD (EIMD Objetivo Métodos scholar 2022 sesgo Resultados general WMD 1285 12 85 12,8 UI L1, L1 L 1, 1 L-1 95% 95 3594 35 94 −35,94 61,64 6164 61 64 0,606. 0606 0,606 . 0 606 0,606) prueba 99080 990 80 990,80 0000 000 0,000 I 967 96 7 96, %. % %) embargo 6105 6 105 −6,10 mm 11193 11 193 −11,19 −1,017 1017 017 0,019. 0019 0,019 019 0,019) Conclusión subgrupos Así ejercicios II manuscritos 202 128 8 12, L- 9 359 3 −35,9 61,6 616 060 0,60 60 9908 99 990,8 00 0,00 610 10 −6,1 1119 19 −11,1 −1,01 101 01 001 0,01 20 −35, 61, 06 0,6 990, 0,0 −6, 111 −11, −1,0 2 −35 0, −6 −11 −1, −3 − −1

ABSTRACT Introduction: Cherry extract has a high amount of anthocyanins and flavonoids containing antioxidant effects. Its high antioxidant characteristics have been shown to reduce markers of delayed muscle soreness (DOMS) and exercise-induced muscle damage (EIMD) to improve recovery after exercise. Objective: Verify the effects of the cherry extract on post-exercise muscle damage. Methods: Google scholar, Medline, and Scopus were systematically searched until February 2022. The Cochrane Collaboration tool was applied to determine the risks of bias. Results: The results showed that cherry extract administration did not have a decreasing impact on creatine kinase levels overall: (WMD = 12.85 IU. L-1, 95% CI: −35.94, 61.64; P = 0.606). Considerable heterogeneity was observed among the articles (Cochran's Q-test = 990.80, P = 0.000, I2 = 96.7 %). However, there is a significant reducing effect on pain sensation by the consumption of cherry extract (WMD = −6.105 mm; 95% CI: −11.193 −1.017; p = 0.019). Conclusion: Cherry extract consumption effectively reduced late-onset muscle pain among participants in the overall and subgroup analysis. Thus, the cherry extract may be a complementary alternative in recovery after exercise. Level of evidence II; Therapeutic studies - Manuscript review. Introduction DOMS (DOMS exerciseinduced exercise induced EIMD (EIMD Objective postexercise post Methods scholar Medline 2022 bias Results WMD 1285 12 85 12.8 IU L1, L1 L 1, 1 L-1 95 CI 3594 35 94 −35.94 61.64 6164 61 64 0.606. 0606 0.606 . 0 606 0.606) Cochrans Cochran s Qtest Q test 99080 990 80 990.80 0000 000 0.000 I 967 96 7 96. %. % %) However 6105 6 105 −6.10 mm 11193 11 193 −11.19 −1.017 1017 017 0.019. 0019 0.019 019 0.019) Conclusion lateonset late onset analysis Thus II review 202 128 8 12. L- 9 359 3 −35.9 61.6 616 060 0.60 60 9908 99 990.8 00 0.00 610 10 −6.1 1119 19 −11.1 −1.01 101 01 001 0.01 20 −35. 61. 06 0.6 990. 0.0 −6. 111 −11. −1.0 2 −35 0. −6 −11 −1. −3 − −1

RESUMO Introdução: O extrato de cereja tem uma alta quantidade de antocianinas e flavonóides contendo efeitos antioxidantes. Suas altas características antioxidantes demonstraram reduzir os marcadores de dor muscular retardada (DOMS) e dano muscular induzido pelo exercício (EIMD) para melhorar a recuperação após o exercício. Objetivo: Verificar os efeitos do extrato de cereja nos danos musculares pós-exercício. Métodos: Google scholar, Medline e Scopus foram sistematicamente pesquisados até fevereiro de 2022. A ferramenta de colaboração da Cochrane foi aplicada para determinar os riscos de viés. Resultados: Os resultados mostraram que a administração do extrato de cereja não teve um impacto decrescente nos níveis de creatina quinase em geral: (WMD = 12,85 IU. L-1, 95% CI: −35,94, 61,64; P = 0,606). Uma heterogeneidade considerável foi observada entre os artigos (teste Q da Cochran = 990,80, P = 0,000, I2 = 96,7 %). Porém, há um efeito redutor significativo na sensação de dor pelo consumo de extrato de cereja (WMD = −6,105 mm; 95% CI: −11,193 −1,017; p = 0,019). Conclusão: O consumo de extrato de cereja foi efetivo na redução de dores musculares de início tardio entre os participantes, na análise geral e nos subgrupos. Assim, o extrato de cereja pode ser uma alternativa complementar na recuperação após os exercícios. Nível de evidência II; Estudos terapêuticos - Revisão de manuscritos. Introdução DOMS (DOMS EIMD (EIMD Objetivo pósexercício. pósexercício pós pós-exercício Métodos scholar 2022 viés Resultados WMD 1285 12 85 12,8 IU L1, L1 L 1, 1 L-1 95 CI 3594 35 94 −35,94 61,64 6164 61 64 0,606. 0606 0,606 . 0 606 0,606) teste 99080 990 80 990,80 0000 000 0,000 I 967 96 7 96, %. % %) Porém 6105 6 105 −6,10 mm 11193 11 193 −11,19 −1,017 1017 017 0,019. 0019 0,019 019 0,019) Conclusão participantes subgrupos Assim exercícios II manuscritos 202 128 8 12, L- 9 359 3 −35,9 61,6 616 060 0,60 60 9908 99 990,8 00 0,00 610 10 −6,1 1119 19 −11,1 −1,01 101 01 001 0,01 20 −35, 61, 06 0,6 990, 0,0 −6, 111 −11, −1,0 2 −35 0, −6 −11 −1, −3 − −1

Abstract Introduction: type 2 diabetes (T2DM) is a complex disease affected by lifestyle and genetic factors. Although the drugs currently used to treat T2DM have certain curative effects, they still have some adverse side effects. Therefore, it is urgent to find new effective drugs with few side effects to cure T2DM. Objective: to study the role of Inonotus obliquus (IO) in diabetic model mice. Methods: we used high-fat diet (HFD) combined with streptozocin (STZ) to establish a diabetic mouse model. Mice were divided into non-high-fat diet group (ND), diabetes model group (HFD + STZ) and IO-treated diabetes model group (IO). The mice in the IO group were orally treated with IO (150 mg/kg) at 10 ml/kg for five weeks. Body weight, glucose level, food intake and water consumption, glucose tolerance and insulin tolerance were evaluated in all mice. The pathological sections of liver, kidney and pancreas were observed by hematoxylin-eosin staining. Results: after IO administration, the blood glucose level, water consumption, low-density lipoprotein (LDL) and triacylglycerol (TG) levels of mice decreased. Compared with the HFD + STZ group, the number of normal islet iiiiiiii cells increased and focal necrosis of the liver was significantly reduced in the IO administration group. Conclusions: IO reduced the levels of blood glucose, restored body weight, and enhanced insulin sensitivity along with insulin tolerance and glucose tolerance in diabetic mice. Additionally, IO also reversed HFD and STZ-induced organ injury.

Resumen Introducción: la diabetes mellitus tipo 2 (T2DM) es una enfermedad compleja influenciada por el estilo de vida y los factores genéticos. En la actualidad, aunque los medicamentos para la diabetes tipo 2 tienen cierto efecto curativo, todavía tienen algunos efectos secundarios. Por lo tanto, es urgente encontrar nuevos medicamentos para la diabetes tipo 2 que tengan un buen efecto curativo y menos efectos secundarios. Objetivo: estudiar el papel del Inonotus obliquus (IO) en ratones diabéticos. Métodos: se estableció un modelo de ratón diabético con dieta de alto contenido en grasas (HFD) y estreptozocina (STZ). Los ratones se dividieron en el grupo de dieta no alta en grasas (ND), el grupo modelo de diabetes mellitus (HFD + STZ) y el grupo modelo de diabetes mellitus tratado con IO. Los ratones del grupo IO recibieron 10 ml/kg de IO (150 mg/kg) durante cinco semanas. Se observaron el peso corporal, el nivel de azúcar en sangre, la ingesta de alimentos, la ingesta de agua potable, la tolerancia a la glucosa y la tolerancia a la insulina de los ratones de cada grupo, y se estudiaron muestras de biopsias hepáticas, renales y pancreáticas mediante tinción de hematoxilina eosina. Resultados: los niveles de glucosa en sangre, el consumo de agua, la lipoproteína de baja densidad (LDL) y los triglicéridos (TG) disminuyeron después de la administración de IO. En comparación con el grupo HFD+STZ, el número de células β pancreáticas normales y la necrosis focal hepática disminuyeron significativamente en el grupo IO. Conclusiones: el IO redujo el nivel de glucosa en sangre, ayudó a recuperar el peso corporal y mejorar la sensibilidad a la insulina, la tolerancia a la insulina y la tolerancia a la glucosa en ratones diabéticos. Además, el IO revirtió el daño orgánico inducido por HFD y STZ.

RESUMO Objetivo: Explorar a influência do curso opcional de voleibol sobre a saúde física dos estudantes universitários. Método: Neste estudo, 160 estudantes universitários (n=89, feminino (n=71)) da série 2019 da Escola T foram selecionados como objetos de pesquisa, com idades entre 19-21 anos. Através de revisão de literatura, entrevista, medição e estatísticas matemáticas, este trabalho testa a qualidade da força dos estudantes, a qualidade da velocidade, a qualidade da resistência e a flexibilidade. Resultados: O índice médio de 1000 metros antes e depois do curso eletivo de voleibol para estudantes masculinos, índice médio de 800 metros antes e depois do curso eletivo de voleibol feminino, a comparação do salto em distância, o índice médio de 50 metros entre estudantes masculinos e femininos antes e depois da aula eletiva de voleibol apresentaram uma significante diferença estatística (P < 0,05). Entretanto, o índice médio comparativo dos dados antes e depois da aula eletiva de pull-up, sit-up e flexão sentada após o voleibol não apresenta diferença estatística. Conclusão: O estudo demonstra que o treinamento na aula de vôlei tem um impacto positivo sobre a saúde física dos estudantes universitários. Nível de evidência II; Estudos terapêuticos – investigação de resultados de tratamento.

ABSTRACT Objective: To explore the influence of volleyball elective course on college students’ physical health. Methods: In this study, 160 college students (n=89, female (n=71)) of the 2019 series of School T were selected as research subjects, aged 19-21 years. Through literature review, interview, measurement and mathematical statistics, this paper tests students’ strength quality, speed quality, endurance quality and flexibility. Results: the average index of 1000 meters before and after the elective volleyball course for male students; average index of 800 meters before and after the elective volleyball course for female students; The comparison of long jump and average index of 50 meters between male and female students before and after the elective volleyball class shows a significant statistical difference (P < 0.05). However, the comparative mean index of the data before and after the pull-up, sit-up and sit-up flexion elective class after volleyball shows no statistical difference. Conclusion: The study demonstrates that training in volleyball class has a positive impact on the physical health of college students. Level of evidence II; Therapeutic studies - investigation of treatment results.

RESUMEN Objetivo: Explorar la influencia del curso optativo de voleibol en la salud física de los estudiantes universitarios. Método: En este estudio, se seleccionaron como sujetos de investigación 160 estudiantes universitarios (n=89, mujeres (n=71)) de la serie 2019 de la Escuela T, de entre 19 y 21 años. A través de la revisión de la literatura, la entrevista, la medición y la estadística matemática, este trabajo pone a prueba la calidad de la fuerza, la calidad de la velocidad, la calidad de la resistencia y la flexibilidad de los estudiantes. Resultados: el índice medio de 1000 metros antes y después del curso de voleibol optativo para los alumnos varones; el índice medio de 800 metros antes y después del curso de voleibol optativo para las alumnas; la comparación del salto de longitud y el índice medio de 50 metros entre los alumnos varones y las alumnas antes y después de la clase de voleibol optativo muestra una diferencia estadística significativa (P < 0,05). Sin embargo, el índice medio comparativo de los datos antes y después de la clase electiva de pull-up, sit-up y flexión sentada después del voleibol no muestra ninguna diferencia estadística. Conclusión: El estudio demuestra que el entrenamiento en la clase de voleibol tiene un impacto positivo en la salud física de los estudiantes universitarios. Nivel de evidencia II; Estudios terapéuticos – investigación de resultados de tratamiento.