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ABSTRACT Background: To analyze the temporal evolution of research on Neglected Tropical Diseases (NTDs) published by the Journal of the Brazilian Society of Tropical Medicine (JBSTM). Methods: We performed an analysis of the scientific production in JBSTM on NTDs using an advanced search, which included authors’ descriptors, title, and abstract, and by combining specific terms for each NTDs from 1991 to 2021. Data related to authors, countries of origin, institutions, and descriptors, were evaluated and analyzed over time. Bibliographic networks were constructed using VOSviewer 1.6.16. Results: The JBSTM published 4,268 scientific papers during this period. Of these 1,849 (43.3%) were related to NTDs. The number of publications on NTDs increased by approximately 2.4-fold, from 352 (total 724) during 1991-2000 to 841 (total 2,128) during 2011-2021, despite the proportional reduction (48.6% versus 39.5%). The most common singular NTDs subject of publications included Chagas disease (31.4%; 581/1,849), leishmaniasis (25.5%, 411/1,849), dengue (9.4%, 174/1,849), schistosomiasis (9.0%; 166/1,849), and leprosy (6.5%, 120/1,849), with authorship mostly from Brazil’s South and Southeast regions. Conclusions: Despite the proportional reduction in publications, JBSTM remains an important vehicle for disseminating research on NTDs during this period. There is a need to strengthen the research and subsequent publications on specific NTDs. Institutions working and publishing on NTDs in the country were concentrated in the South and Southeast regions, requiring additional investments in institutions in other regions of the country. Background (NTDs JBSTM. . (JBSTM) Methods search authors descriptors title abstract 199 2021 origin time 1616 1 6 16 1.6.16 Results 4268 4 268 4,26 period 1849 849 1,84 43.3% 433 43 3 (43.3% 2.4fold, 24fold fold 2.4 fold, 2 2.4-fold 35 total 724 19912000 2000 1991-200 84 2,128 2128 128 20112021, 20112021 2011 2021, 2011-2021 48.6% 486 48 (48.6 39.5%. 395 39.5% 39 5 39.5%) 31.4% 314 31 (31.4% 581/1,849, 5811849 581/1,849 , 581 581/1,849) 25.5%, 255 25 (25.5% 411/1,849, 4111849 411/1,849 411 411/1,849) 9.4%, 94 9 (9.4% 174/1,849, 1741849 174/1,849 174 174/1,849) 9.0% 90 0 (9.0% 166/1,849, 1661849 166/1,849 166 166/1,849) 6.5%, 65 (6.5% 120/1,849, 1201849 120/1,849 120 120/1,849) Brazils Brazil s Conclusions (JBSTM 19 202 161 1.6.1 426 26 4,2 184 1,8 43.3 (43.3 4fold 2.4fold 24 2. 72 1991200 200 1991-20 8 2,12 212 12 2011202 201 2011-202 48.6 (48. 39.5 31.4 (31.4 581184 581/1,84 58 25.5% (25.5 411184 411/1,84 41 9.4% (9.4 174184 174/1,84 17 9.0 (9.0 166184 166/1,84 6.5% (6.5 120184 120/1,84 20 1.6. 42 4, 18 1, 43. (43. 7 199120 1991-2 2,1 21 201120 2011-20 48. (48 39. 31. (31. 58118 581/1,8 25.5 (25. 41118 411/1,8 9.4 (9. 17418 174/1,8 9. 16618 166/1,8 6.5 (6. 12018 120/1,8 1.6 (43 19912 1991- 2, 20112 2011-2 (4 (31 5811 581/1, 25. (25 4111 411/1, (9 1741 174/1, 1661 166/1, 6. (6 1201 120/1, 1. 2011- ( (3 581/1 (2 411/1 174/1 166/1 120/1 581/ 411/ 174/ 166/ 120/