Resumo A reciclagem de resíduos de construção e demolição (RCD) pode contribuir como uma fonte de agregados, materiais cuja a produção é cada vez mais difícil. Contribuiu também para a redução do descarte inadequado desses resíduos. Diferentes autores mostram que é possível produzir agregados reciclados de alta qualidade, com baixo teor de pasta de cimento em sua superfície, utilizando operações de processamento mineral. Uma opção com bom potencial de aplicação é a cominuição seletiva, onde um moinho autógeno ou com baixa carga de bolas pode ser utilizado para remover a pasta de cimento aderida aos agregados sem muita cominuição dos próprios agregados, em um mecanismo de polimento de grãos. Apesar dos bons resultados obtidos para redução da absorção de água relatados na literatura, faltam pesquisas quantificando o consumo de energia. O presente trabalho investigou a influência da cominuição seletiva nas propriedades do agregado fino de concreto reciclado, na faixa de 4.8 mm a 0.15 mm. Os resultados indicaram que foi possível reduzir a absorção de água abaixo de 3% com um consumo de energia inferior a 5 kWh/t, confirmando assim que a cominuição seletiva de baixo consumo energético pode ser uma alternativa útil para obter um agregado reciclado de alta qualidade. RCD (RCD difícil qualidade superfície mineral grãos literatura 48 4 8 4. 015 0 15 0.1 3 kWht kWh t kWh/t 01 1 0.

Abstract The recycling of construction and demolition waste (CDW) can contribute as a source of aggregates, materials whose production is increasingly difficult. It will also contribute to a reduction of inappropriate disposal of these residues. Different authors show that it is possible to produce high quality recycled aggregates, with low cement paste on its surface, using mineral processing operations. One option that has a good potential application is selective comminution, where an autogenous or a low charge ball mill can be used to remove the cement past adhered to the aggregates without much comminution of the aggregates itself, i.e., in a grain polishing mechanism. Despite the good results obtained for water absorption reduction as reported in the literature, there is a lack of research focused on the selective comminution of CDW quantifying the energy usage. The present work investigated the influence of selective grinding on the properties of fine recycled concrete aggregate, between 4.8 mm and 0.15 mm. The results indicated that it was possible to reduce the water absorption below 3% with an energy consumption of less than 5 kWh/t, thus confirming that low-energy selective comminution can be a useful alternative to obtain a high-quality recycled aggregate. (CDW difficult residues surface operations itself ie i e i.e. mechanism literature usage aggregate 48 4 8 4. 015 0 15 0.1 3 kWht kWh t kWh/t lowenergy highquality i.e 01 1 0.

Resumo A trabalhabilidade das argamassas resulta de outras propriedades, como consistência, plasticidade, coesão, retenção de água, exsudação, adesão inicial e densidade. Uma argamassa trabalhável distribui-se durante a aplicação, não segrega durante o transporte e permanece plástica durante o tempo de aplicação. Esta propriedade depende de vários fatores de aplicação, juntamente com os materiais constituintes. Portanto, este estudo tem como objetivo avaliar a influência da formulação, do tipo de agregado e do teor de água no comportamento reológico de argamassas de reboco, aliado a estudos de empacotamento de partículas. Para tanto, foram escolhidas três formulações de argamassas usuais. O teor mínimo de água foi calculado através dos conceitos de empacotamento de partículas e teste de squeeze flow. Como resultado, foi determinada a influência de cada constituinte na trabalhabilidade da argamassa, juntamente com as formulações otimizadas pelo tipo de agregado. A análise do teor de água revelou a densidade de empacotamento úmido e o valor mínimo necessário para a formação do filme de água ao redor das partículas. propriedades consistência plasticidade coesão exsudação distribuise distribui se aplicação constituintes Portanto formulação reboco tanto usuais flow resultado

Abstract Mortars’ workability results from other properties, such as consistency, plasticity, cohesion, water retention, exudation, initial adhesion and density. A workable mortar distributes itself in application, doesn’t segregate during transport, and remains plastic during the application time. This property depends on several application factors, together with the constituent materials. Therefore, this study aims to assess the influence of the formulation, aggregate type and water content on rheological behavior of rendering mortars, combined with particle packing studies. For this purpose, three usual mortar formulations were chosen. The minimum water content was calculated through the concepts of particle packing and the squeeze flow test. As a result, the influence of each constituent on the workability of the mortar was determined, together with the formulations optimized by the aggregate type. The water content analysis revealed the wet packing density and minimum value required for the formation of the water film around the particles. Mortars properties consistency plasticity cohesion retention exudation doesnt doesn t transport time factors materials Therefore formulation mortars studies purpose chosen test result determined particles

Abstract This study aimed to do a short and single survey of the diversity of mosquitoes found in tree holes within a fragment of Atlantic Forest in Rio Grande do Norte, Brazil. Larvae were collected through active search, inspecting tree cavities and collecting water and larvae using a homemade siphon on a single day. Eight species of Culicidae were recorded from the surveyed tree holes. Haemagogus leucocelaenus (Dyar & Shannon, 1924) and Haemagogus janthinomys Dyar, 1921 were the most abundant species, accounting for 63.1% of the total specimens collected, followed by Culex (Microculex) sp. (12.20%), Aedes terrens (Walker, 1856) (5.26%) and Aedes fulvithorax (Lutz, 1904) (1.75 %). Although there are other breeding sites in nature (bromeliads and bamboos), tree holes in native trees play a fundamental role in maintaining and conserving the culicid fauna due to their water storage capacity, especially in wild species, such as species of the genus Haemagogus Williston, 1896.

Resumen Esta investigación tuvo como objetivo realizar un estudio breve y único sobre la diversidad de mosquitos encontrados en cavidades de árboles dentro de un fragmento de Bosque Atlántico en Rio Grande do Norte, Brasil. Las larvas fueron recolectadas mediante búsqueda activa, inspeccionando cavidades de árboles y recolectando agua con larvas utilizando un sifón casero en un solo día. Se registraron ocho especies de Culicidae en las cavidades de árboles muestreados. Haemagogus leucocelaenus (Dyar y Shannon, 1924) y Haemagogus janthinomys Dyar, 1921 fueron las especies más abundantes, representando el 63,1% del total de especímenes recolectados, seguidas por Culex (Microculex) sp. (12,20%), Aedes terrens (Walker, 1856) (5,26%) y Aedes fulvithorax (Lutz, 1904) (1,75%). Aunque existen otros sitios de cría en la naturaleza (bromelias y bambúes), las cavidades presentes en árboles nativos desempeñan un papel fundamental en el mantenimiento y conservación de la fauna de culícidos debido a su capacidad de almacenamiento de agua, especialmente en especies silvestres pertenecientes al género Haemagogus Williston, 1896.

ABSTRACT This study aimed to evaluate the use of microalgae meal (Aurantiochytrium sp. and Nannochloropsis spp.) as a substitute for fish oil in the diet of shrimp Penaeus vannamei reared in a clear water system. In the diet of these animals, the concentration of fish oil decreased as microalgae meal was inserted, and these were used in five different substitutions: 0, 25, 50, 75, and 100%. The treatments were carried out in triplicate, and after 49 days of cultivation, the zootechnical parameters and the composition of fatty acids in the animals’ muscles were analyzed. In zootechnical performance, the shrimp obtained an average final weight of 16.59 ± 0.3 g, and the growth was approximately 1.89 ± 0.30 g week−1. In addition, feed conversion was, on average, 1.47 ± 0.28, and survival was greater than 97%. However, no significant difference was observed in these parameters. Regardless of the levels of fish oil replacement by microalgae meal, the composition of fatty acids in the shrimp muscle was ensured, as well as their quantity within groups, such as n-3 and n-6 polyunsaturated fatty acids. Thus, with the results obtained in the present study, it is suggested that it is possible to formulate a high-performance diet without any ingredients of marine origin (fish oil or fish meal), contributing to aquaculture's sustainability.

ABSTRACT Studies on the adaptability of raspberry cultivars to subtropical regions are needed since growth, yield, and fruit quality may differ from levels observed in temperate climates. This study evaluated the phenology, yield, physical-chemical attributes, and bioactive compounds of raspberries produced in a subtropical region of Brazil under an organic cropping system. The experiment was carried out in three production cycles 2018/2019, 2019/2020, and 2020/2021 in Pinhais, Paraná State, Brazil. We evaluated ten raspberry cultivars, eight primocanes (Alemãzinha, Autumn Bliss, Bababerry, Fallgold, Golden Bliss, Heritage, Indian Summer and Polana), and two floricane cultivars (Schoenmann and Willamette). Phenological evaluations were carried out weekly at the beginning and end of flowering and harvesting. The soluble solids content, titratable acidity, the pH, and bioactive compounds were analyzed. Primocane cultivars showed two flowering and fruiting periods, the first in spring/summer and the other in summer/autumn, except for the Indian Summer cultivar, which showed a floricane-fruiting behavior, bearing fruit only on one-year-old canes, like Schoenmann and Willamette cultivars. ‘Alemãzinha’ shows better adaptation to the region under study with higher yield and concentration of total polyphenols, but its fruits are small and acidic. ‘Heritage’ is also an option for cultivation in this region, even though it is less productive, as the fruits are larger, less acidic, and have high levels of bioactive compounds. Yellow cultivars Fallgold and Golden Bliss are good options for diversifying the color offer, with yields similar to ‘Heritage’ and with a high total soluble solids/titratable acidity ratio. growth climates phenology physicalchemical physical chemical attributes system 20182019 2018 2019 2018/2019 20192020 2020 2019/2020 20202021 2021 2020/202 Pinhais State Alemãzinha, Alemãzinha (Alemãzinha Bababerry Heritage Polana, Polana , Polana) Willamette. . Willamette) harvesting content pH analyzed periods springsummer spring summer summerautumn autumn summer/autumn cultivar floricanefruiting behavior oneyearold one year old canes ‘Alemãzinha polyphenols acidic ‘Heritage productive larger offer solidstitratable ratio 2018201 201 2018/201 2019202 202 2019/202 2020202 2020/20 201820 20 2018/20 201920 2019/20 202020 2020/2 20182 2 2018/2 20192 2019/2 20202 2020/ 2018/ 2019/

It is particularly important to investigate the mechanical performance of carbon fiber (CF) reinforced polyamide 6 (PA6) composites used for automotive and aerospace applications, where diffused moisture of the environment may potentially weaken the material over time. In this work, CF/PA6 composites were subjected to two different types of conditioning: distilled water at a temperature of 80 ºC and saline solution for 12 weeks. The volumetric fraction of CF, PA6 matrix, and the voids of the CF/PA6 composites were determined by acid digestion analysis. At the end of the environmental conditionings, the moisture absorption content and the diffusion coefficient (D) were determined. The mechanical performance of CF/PA6 composites unconditioned and conditioned was evaluated through tensile and interlaminar shear strength (ILSS) tests, and morphological characteristics of the fracture surface after the mechanical tensile test. CF/PA6 composites conditioned in saline solution showed a decrease of 53% (tensile sample) and 72% (ILSS sample) in the diffusion coefficient (D) and insignificant losses of mechanical properties when compared to CF/PA6 composites conditioned in distilled water at 80 ºC. This behavior is attributed to the salt molecules blocking the pores and consequently reducing the migration of water into the samples, maintaining the internal integrity of the specimens. CF (CF PA (PA6 applications time work CFPA6 CFPA CF/PA conditioning 8 1 weeks matrix analysis conditionings D (D ILSS tests test 53 sample 72 samples specimens (PA 5 7

Resumo Objetivo Investigar a aceitação e adequação de um programa de exercícios multicomponentes por videoconferência para longevos em Porto Alegre (RS), Brasil. Método Estudo Quase experimental. Os participantes realizaram o protocolo de exercícios multicomponentes ViviFrail® durante 12 semanas, com a aceitação e adequação avaliadas semanalmente por videoconferência. O questionário de aceitação e adequação foi baseado em uma escala Likert (de 0 a 4) de seis barreiras que os participantes enfrentam ao fazer exercício físico, com pontuação máxima de 24 pontos (aceitação máxima). Resultados A aceitação foi de 70%, com 14 participantes concluindo o protocolo (89,07±6,30 anos). A consistência interna, (alfa de Cronbach) para o questionário, foi de 70%, considerada moderada. Os participantes mostraram um aumento geral na aceitação dos 17,8±3,51 pontos iniciais, para 22,0±2,94 pontos no final. Quatro (28.6%) necessitaram de adequação no protocolo de exercício. Conclusão O programa de exercícios multicomponente ViviFrail®, com acompanhamento através de videoconferência, foi bem aceito e adequado, podendo ser uma importante ferramenta para a promoção da qualidade de vida, principalmente em longevos com dificuldade de sair de casa, tanto por problemas de mobilidade, quanto por ambientes sociais desfavoráveis (violência urbana e situações sanitárias). O questionário de aceitação e adequação, que necessitou ser criado, foi capaz de detectar barreiras do RS, RS , (RS) Brasil experimental ViviFrail 1 semanas 4 físico 2 máxima. . máxima) 70 70% 89,07±6,30 8907630 89 07 6 30 (89,07±6,3 anos. anos anos) interna alfa Cronbach moderada 178351 17 8 3 51 17,8±3,5 iniciais 220294 22 94 22,0±2,9 final 28.6% 286 28 (28.6% adequado vida casa mobilidade violência sanitárias. sanitárias sanitárias) criado (RS 7 89,07±6,3 890763 (89,07±6, 17835 5 17,8±3, 22029 9 22,0±2, 28.6 (28.6 89,07±6, 89076 (89,07±6 1783 17,8±3 2202 22,0±2 28. (28. 89,07±6 8907 (89,07± 178 17,8± 220 22,0± (28 89,07± 890 (89,07 17,8 22,0 (2 89,07 (89,0 17, 22, ( 89,0 (89, 89, (89 (8

Abstract Objective To investigate the acceptability and adequacy of a multicomponent exercise program via videoconferencing for the oldest-old in Porto Alegre, a city in southern Brazil. Method This is a quasi-experimental study. Fourteen participants were enrolled in the multicomponent exercise program Vivifrail® for 12 weeks, 5 days a week, with weekly video calls for assessment of acceptability and adequacy. The acceptability and adequacy questionnaire was based on 6 barriers that older adults face when engaging in physical exercise. Responses were measured using a 5-point Likert scale ranging from 0 to 4 points, with a maximum score of 24 points (maximum acceptability). Results Fourteen participants (89.07±6.30 years) concluded the protocol, with an acceptability rate of 70%. Internal consistency was moderate, with a Cronbach’s coefficient alpha of 0.7. Participants showed an overall increase in acceptability and adequacy (from 17.8±3.51 points in the first week to 22.0±2.94 in the 12th week). Four participants (28.6%) required some modification to the exercise protocol. Conclusion The Vivifrail® protocol, together with weekly follow-up via videoconferencing, was well accepted and adequate. It could be an important tool for promoting quality of life, especially in the oldest-old with difficulty leaving home. The acceptability questionnaire was able to detect exercise barriers and suggest possible modifications to the training program and could be presented as a suggestion for the evaluation of intervention protocols in the oldest-old population. Therefore, the Vivifrail® protocol, with weekly follow-up via videoconferencing, could be a new field of intervention for health professionals. oldestold oldest old Alegre Brazil quasiexperimental quasi experimental study Vivifrail 1 weeks 5point point 2 acceptability. . acceptability) 89.07±6.30 8907630 89 07 30 (89.07±6.3 years protocol 70 70% moderate Cronbachs Cronbach s 7 0.7 178351 17 8 3 51 17.8±3.5 220294 22 94 22.0±2.9 th week. week) 28.6% 286 28 (28.6% followup follow up adequate life home population Therefore professionals 89.07±6.3 890763 (89.07±6. 0. 17835 17.8±3. 22029 9 22.0±2. 28.6 (28.6 89.07±6. 89076 (89.07±6 1783 17.8±3 2202 22.0±2 28. (28. 89.07±6 8907 (89.07± 178 17.8± 220 22.0± (28 89.07± 890 (89.07 17.8 22.0 (2 89.07 (89.0 17. 22. ( 89.0 (89. 89. (89 (8

Resumo A automedicação expõe os indivíduos a riscos como reações adversas, intoxicações, interações medicamentosas, falhas terapêuticas e erros de medicação. Na pandemia de Covid-19, houve aumento de compra e consumo de produtos farmacêuticos pelos brasileiros. O presente estudo teve como objetivo estimar a prevalência e os fatores associados à automedicação em estudantes de um centro universitário na região do Campo das Vertentes, Minas Gerais, bem como avaliar a incidência durante a pandemia de Covid-19. O estudo teve delineamento transversal e quantitativo, com 248 estudantes de um centro universitário em 2021. Os achados mostraram que 67,3% dos participantes relataram realizar a automedicação; 28,7% apontaram aumento da automedicação durante a pandemia; e 30,9% indicaram o início nesse período. Houve diferença significativa sobre: considerar-se capaz de se automedicar, ter costume de indicar medicamentos para outras pessoas e consumi-los por indicação de outros. Para aqueles que aumentaram a prática de automedicação na pandemia, houve associação com o hábito de indicar medicamentos para outras pessoas. Já para quem iniciou essa prática no período pandêmico, a capacidade de automedicação esteve associada. Os resultados abrem caminhos para medidas educativas sobre o uso irracional dos medicamentos pelos estudantes do ensino superior, independentemente da área de formação. adversas intoxicações medicamentosas medicação Covid19, Covid19 Covid 19, 19 Covid-19 brasileiros Vertentes Gerais Covid19. 19. quantitativo 24 2021 673 67 3 67,3 287 28 7 28,7 309 30 9 30,9 considerarse considerar automedicar consumilos consumi los outros pandêmico associada superior formação Covid1 1 Covid-1 2 202 6 67, 28, 30, Covid- 20

Abstract Self-medication exposes individuals to risks such as adverse reactions, intoxications, drug interactions, therapeutic failures and medication errors. In the COVID-19 pandemic, there was an increase in the purchase and consumption of pharmaceutical products by Brazilians. The present study aimed to estimate the prevalence and factors associated with self-medication in students of a university center in the region of Campo das Vertentes, Southeastern Brazil, as well as to evaluate the incidence during the COVID-19 pandemic. The study had a cross-sectional and quantitative design, with 248 students from a university, in 2021. The findings showed that 67.3% of the participants reported self-medication; 28.7% indicated an increase in self-medication during the pandemic; and 30.9% indicated the beginning in this period. There was a significant difference about: to consider oneself capable of self-medicating, to have the habit of referring drugs to other people and to consume them by indication of others. For those who increased the practice of self-medication in the pandemic, there was an association with the habit of indicating drugs to other people. For those who initiated this practice in the pandemic period, the capacity of self-medication was associated. The results open paths for educational measures on the irrational use of medicines by higher education students, regardless of the education area. Selfmedication Self reactions intoxications interactions errors COVID19 COVID 19 COVID-1 Brazilians selfmedication self Vertentes Brazil crosssectional cross sectional design 24 2021 673 67 3 67.3 287 28 7 28.7 309 30 9 30.9 period about selfmedicating, selfmedicating medicating, medicating self-medicating others area COVID1 1 COVID- 2 202 6 67. 28. 30. 20

Resumen La automedicación expone a los individuos a riesgos tales como reacciones adversas, intoxicaciones, interacciones medicamentosas, fracasos terapéuticos y errores medicamentosos. En la pandemia de Covid-19, hubo un aumento en la compra y consumo de productos farmacéuticos por parte de los brasileños. El presente estudio tuvo como objetivo estimar la prevalencia y los factores asociados a la automedicación en estudiantes de un centro universitario en la región de Campo das Vertentes, Sudeste de Brasil, así como evaluar la incidencia durante la pandemia de Covid-19. El estudio tuvo un diseño transversal y cuantitativo, con 248 estudiantes de un centro universitario en 2021. Los hallazgos mostraron que el 67,3% de los participantes reportaron automedicación; el 28,7% indicó un aumento en la automedicación durante la pandemia; y el 30,9% indicó el inicio en este período. Hubo una diferencia significativa en: Considerarse capaz de automedicarse, tener el hábito de referir drogas a otras personas y consumirlas por indicación de otros. Para aquellos que incrementaron la práctica de la automedicación en la pandemia, hubo una asociación con el hábito de indicar drogas a otras personas. Para aquellos que iniciaron esta práctica en el período pandémico, se asoció la capacidad de automedicación. Los resultados abren caminos para medidas educativas sobre el uso irracional de medicamentos por parte de los estudiantes de educación superior, independientemente del área de formación. adversas intoxicaciones medicamentosas medicamentosos Covid19, Covid19 Covid 19, 19 Covid-19 brasileños Vertentes Brasil Covid19. 19. cuantitativo 24 2021 673 67 3 67,3 287 28 7 28,7 309 30 9 30,9 automedicarse otros pandémico superior formación Covid1 1 Covid-1 2 202 6 67, 28, 30, Covid- 20

Resumo Para cumprir os requisitos de desempenho das pastas autonivelantes, a sua fluidez está ligada à ausência de segregação ou exsudação, o que torna obrigatória uma elevada coesão entre os componentes. Assim, a dosagem ideal destes materiais é um tópico essencial para proporcionar estas propriedades específicas. Para avaliar o efeito da composição no estado fresco, foi proposto um método para quantificar a uniformidade das pastas autonivelantes através da análise do diâmetro e das bordas das pastas espalhadas. Assim, foram testadas diferentes dosagens variando alguns teores de insumos. A uniformidade foi quantificada com o desenvolvimento de índices como a Razão de Perímetro (RP) e a Relação de Insumos (RI). Concluiu-se que menores diâmetros de espalhamento implicam em maior índice de uniformidade. Além disso, observou-se que, para se obter uma dosagem ideal para as pastas, há uma tendência de correlação direta entre o índice de uniformidade e a relação água/pó (a/p) e o teor de superplastificante (SP) e uma correlação inversa entre este e o aditivo modificador de viscosidade (VMA). exsudação componentes Assim específicas fresco espalhadas insumos RP (RP RI. RI . (RI) Concluiuse Concluiu disso observouse observou águapó água pó a/p ap p (a/p SP (SP VMA. VMA (VMA) (RI (VMA

Abstract To meet the self-leveling pastes’ performance requirements, its flowability is linked to the absence of segregation or exudation, which makes a high cohesion between the components mandatory. Therefore, the ideal dosage for these materials is an essential topic to provide such specific properties. To evaluate the composition effect on fresh state, a method was proposed to quantify self-leveling pastes’ uniformity through the analysis of the spread pastes’ diameter and borders. Thus, different dosages were tested varying some input contents. The uniformity was quantified with the development of indexes such as Perimeter Ratio (PR) and Input Relation (IR). It was concluded that lower spread diameters incurred in higher uniformity index. Furthermore, it was observed that to achieve an ideal dosage for pastes, there is a tendency of direct correlation between the uniformity index and the water/powder ratio (w/p) and superplasticizer (SP) content and an inverse one between it and viscosity modifying admixture (VMA). selfleveling self leveling pastes requirements exudation mandatory Therefore properties state borders Thus contents PR (PR IR. IR . (IR) Furthermore waterpowder water powder w/p wp w p (w/p SP (SP VMA. VMA (VMA) (IR (VMA

RESUMO Objetivo: Tumores cardíacos pediátricos são raros e, entre eles, 90% são benignos. O fibroma cardíaco é o segundo mais frequente, após o rabdomioma. O objetivo deste trabalho é relatar um caso de fibroma cardíaco, cujo diagnóstico foi incidental em um paciente internado por bronquiolite viral aguda. Descrição do caso: Lactente do sexo masculino com cinco meses foi atendido em um pronto atendimento pediátrico com quadro de bronquiolite viral aguda, necessitando de hospitalização. Em exames complementares, apresentou vírus sincicial respiratório detectável, hemograma com linfocitose, além de radiografia de tórax com cardiomegalia. Em investigação cardiológica, as enzimas cardíacas encontravam-se elevadas, o eletrocardiograma apresentava alteração de repolarização de parede lateral de ventrículo esquerdo e o ecocardiograma demonstrou massa heterogênea em ventrículo esquerdo, com áreas de calcificação. A angiotomografia de tórax sugeriu rabdomiossarcoma ou fibroma cardíaco e a ressonância magnética demonstrou massa cuja localização e características sugeriram fibroma. O diagnóstico foi conclusivo após dois cateterismos para biópsia da lesão, confirmando fibroma cardíaco pelo anatomopatológico. Em razão da disfunção sistólica moderada a grave, o paciente foi submetido a transplante cardíaco. Comentários: Um terço dos fibromas cardíacos é assintomático, geralmente diagnosticado tardiamente por meio de exames solicitados por outro motivo. O padrão-ouro para o diagnóstico definitivo é a biópsia. O fibroma cardíaco não costuma apresentar regressão espontânea, sendo submetido, na maioria dos casos, a ressecção cirúrgica parcial ou total. Nos tumores irressecáveis, o transplante cardíaco deve ser indicado. A caracterização detalhada da massa cardíaca é fundamental para traçar a conduta terapêutica mais adequada para cada paciente. Objetivo eles 90 benignos frequente rabdomioma aguda hospitalização complementares detectável linfocitose cardiomegalia cardiológica encontravamse encontravam se elevadas calcificação lesão anatomopatológico grave Comentários assintomático motivo padrãoouro padrão ouro espontânea casos total irressecáveis indicado 9

ABSTRACT Objective: Pediatric cardiac tumors are rare and, among them, 90% are benign. Cardiac fibroma is the second most frequent tumor, after rhabdomyoma. The objective of this study is to report a case of cardiac fibroma diagnosed incidentally in a patient admitted with acute viral bronchiolitis. Case description: A 5-month-old male infant was admitted to the pediatric emergency department with acute viral bronchiolitis requiring hospitalization. He presented a detectable respiratory syncytial virus in oropharyngeal swab, blood test with lymphocytosis and a chest radiography revealed cardiomegaly. Further cardiologic testing was performed detecting elevation of cardiac biomarkers, an electrocardiogram with alteration of left ventricular repolarization and echocardiogram with a heterogeneous mass in the left ventricular, with areas of calcification. A chest angiotomography suggested rhabdomyosarcoma or cardiac fibroma and a magnetic resonance showed a mass, with characteristics suggesting fibroma. The final diagnosis was made after two cardiac catheterizations for biopsy of the lesion, confirming cardiac fibroma by anatomopathological examination. Because the patient had moderate to severe systolic dysfunction, he was submitted to heart transplant. Comments: One third of cardiac fibromas are asymptomatic, generally diagnosed late through tests ordered for other reasons. The gold-standard test for definitive diagnosis is biopsy. Cardiac fibroma usually does not present spontaneous regression and, in most cases, partial or total surgical resection is necessary. When tumors are unresectable, heart transplantation should be indicated. It is essential to have detailed characterization of the cardiac mass to establish the most appropriate therapeutic approach for each patient. Objective them 90 benign tumor rhabdomyoma description 5monthold monthold 5 month old hospitalization swab cardiomegaly biomarkers calcification lesion examination dysfunction transplant Comments asymptomatic reasons goldstandard gold standard cases necessary unresectable indicated 9

Resumo Objetivo Discutir sobre a promoção da saúde da pessoa idosa por meio da intergeracionalidade, com ênfase na educação intergeracional nos Programas Intergeracionais, como uma proposta de educação para o protagonismo da pessoa idosa e o envelhecimento bem-sucedido. Método Ensaio teórico, de cunho reflexivo com abordagem qualitativa. Embasando-se na leitura de documentos que reforçam o aumento da longevidade e a preocupação com a promoção da saúde para a pessoa idosa no Brasil, a fim de refletir sobre a intergeracionalidade na promoção da saúde e a utilização da educação intergeracional para promover o envelhecimento bem-sucedido, por meio dos Programas Intergeracionais. Resultados Organizaram-se em três tópicos: Promoção da saúde da pessoa idosa: desafios para o seu protagonismo; Compreensão sobre envelhecimento para a aprendizagem intergeracional; Programa intergeracional: protagonismo para a promoção da saúde da pessoa idosa. Conclusão Experiências exitosas na saúde, especificamente nos espaços ocupados pela Atenção Primária à Saúde ainda se mostram restritas ou pouco visualizadas para a construção de uma educação transformadora para a promoção da saúde da pessoa idosa. O desafio é fomentar pesquisas científicas, para que os profissionais, a partir da educação permanente, possam potencializar os momentos de educação em saúde a partir da educação intergeracional, sendo assim, a construção e implementação de Programas Intergeracionais podem representar essa possibilidade. bemsucedido. bemsucedido bem sucedido. sucedido bem-sucedido teórico qualitativa Embasandose Embasando Brasil bemsucedido, sucedido, Organizaramse Organizaram tópicos científicas profissionais permanente assim possibilidade

Abstract Objective To discuss the promotion of health for older adults through intergenerationality, with an emphasis on intergenerational education within Intergenerational Programs, as a proposal for education fostering the protagonism of older adults and successful aging. Method Theoretical essay, reflective in nature with a qualitative approach. Grounded in the examination of documents emphasizing the increase in longevity and the concern for health promotion among older adults in Brazil, the aim is to contemplate intergenerationality in health promotion and the utilization of intergenerational education to foster successful aging through Intergenerational Programs. Results Organized into three topics: Health promotion for older adults: challenges for their protagonism; Understanding aging for intergenerational learning; Intergenerational program: protagonism for the health promotion of older adults. Conclusion Successful experiences in health, specifically within the realms of Primary Health Care, still appear to be limited or insufficiently recognized for the development of transformative education in health promotion for older adults. The challenge lies in fostering scientific research so that professionals, through continuous education, can enhance health education moments through intergenerational education. Thus, the establishment and implementation of Intergenerational Programs may represent this promising possibility. essay approach Brazil topics learning program Care professionals Thus possibility

RESUMO As mudanças ambientais influenciam diretamente a qualidade de vida, e leis de proteção ambiental surgem para garantir a manutenção do equilíbrio ecológico. Os ambientes aquáticos têm sido contaminados por substâncias de origem antrópica, denominadas efluentes. O descarte inadequado de efluentes traz efeitos adversos ao meio ambiente e à saúde humana. Na legislação brasileira, as resoluções do Conselho Nacional do Meio Ambiente (CONAMA) RE 357/2005 e RE 430/2011 abordam o uso de espécies indicadoras para avaliar a toxicidade dos efluentes. Apesar destas, muito ainda precisa ser feito para controlar e monitorar a emissão de efluentes nos recursos hídricos brasileiros. O objetivo deste trabalho foi realizar um levantamento histórico das regulamentações sobre o descarte de efluentes no Brasil e mostrar as diferenças nas regulamentações de cada estado, destacando as espécies indicadoras aceitas em cada regulamentação e suas vantagens e desvantagens. Dessa forma, esta revisão resume e organiza as informações da legislação brasileira sobre o descarte de efluentes e auxilia o pesquisador da área a escolher entre as metodologias adotadas para a análise de suas amostras ambientais. Apesar da inserção de bioensaios, fica evidente que a legislação brasileira atual é permissiva, exigindo adaptações e definições para aumentar a adesão ao monitoramento ecotoxicológico dos recursos hídricos pelos estados. vida ecológico antrópica humana CONAMA (CONAMA 3572005 357 2005 357/200 4302011 430 2011 430/201 destas brasileiros estado desvantagens forma bioensaios permissiva estados 357200 35 200 357/20 430201 43 201 430/20 35720 3 20 357/2 43020 4 430/2 3572 2 357/ 4302 430/

ABSTRACT Environmental changes directly influence quality of life, and environmental protection laws arise to ensure the maintenance of ecological balance. Aquatic environments have been contaminated by substances of anthropic origin, which are called effluents. Improper disposal of effluents has adverse effects on the environment and human health. In Brazilian legislation, the resolutions of the National Council for the Environment (CONAMA) RE 357/2005 and RE 430/2011 address the use of indicator species to evaluate the effluents’ toxicity. Despite these, much still needs to be done to control and monitor the emission of effluents in Brazilian water resources. The objective of this work was to carry out a historical survey of the regulations on the disposal of effluents in Brazil and to show the differences in each state's regulations, highlighting the indicator species accepted in each regulation and their advantages and disadvantages. In this way, this review summarizes and organizes the information of the Brazilian legislation on the disposal of effluents and helps the researcher in the area to choose between the methodologies adopted for the analysis of their environmental samples. Despite the insertion of bioassays, it is evident that the current Brazilian legislation is permissive, requiring adaptations and definitions to increase adherence to the ecotoxicological monitoring of water resources by the States. life balance origin health CONAMA (CONAMA 3572005 357 2005 357/200 4302011 430 2011 430/201 toxicity these states state s disadvantages way samples bioassays permissive States 357200 35 200 357/20 430201 43 201 430/20 35720 3 20 357/2 43020 4 430/2 3572 2 357/ 4302 430/

ABSTRACT Objective: To assess the methodological quality and characteristics of systematic reviews (SRs) of interventional studies in orthodontics and assess how the certainty of the evidence is reported using the GRADE approach. Material and Methods: Six electronic databases were searched, followed by a hand search of the reference lists of eligible studies (PROSPERO #CRD42020180852). The required study design was randomized and nonrandomized studies of interventions published between January 2019 and May 2020. The Assessing the Methodological Quality of Systematic Reviews (AMSTAR 2) tool was used for the quality appraisal of the included SRs. Paired reviewers independently screened the studies, extracted data, and appraised the methodological quality. Results: The study included 46 SRs; 19.5% had moderate to high methodological quality, and the remaining had low to critically low methodological quality. Fifty-four percent of the reviews assessed the certainty of evidence using the GRADE approach, and 34.8% followed all GRADE criteria. Conclusion: Most reviews had a good judgment of the AMSTAR2 items, although some critical items contributed to decreased overall quality. Half of the reviews used the GRADE approach to assess the certainty of the evidence, and this approach should be included in future systematic reviews of interventions. Objective SRs (SRs Methods searched PROSPERO #CRD42020180852. CRD42020180852 CRD #CRD42020180852 . #CRD42020180852) 201 2020 AMSTAR 2 data Results 4 195 19 5 19.5 Fiftyfour Fifty four 348 34 8 34.8 criteria Conclusion CRD4202018085 #CRD4202018085 20 202 1 19. 3 34. CRD420201808 #CRD420201808 CRD42020180 #CRD42020180 CRD4202018 #CRD4202018 CRD420201 #CRD420201 CRD42020 #CRD42020 CRD4202 #CRD4202 CRD420 #CRD420 CRD42 #CRD42 CRD4 #CRD4 #CRD

The study analyzed the impacts of two probiotics (Ecobiol® and GutCare®) on growth performance, carcass and cut yields, intestinal morphometry and lesion score, biochemical parameters, and short-chain fatty acid concentration in chickens using a challenge model combining coccidiosis vaccine and Clostridium perfringens. A total of 880 one-day-old male broilers (Cobb 500) were randomly assigned to four treatments with 10 replicates and 22 birds per experimental unit (EU). The treatments consisted of: PC: positive control with the inclusion of 80 g ton-1 of Enramax® (8% enramycin) until 35 d of age; NC: negative control without the inclusion of growth-promoting probiotic; BA: NC with the inclusion of 1000 g ton-1 of Ecobiol® (Bacillus amyloliquefaciens - CECT 5940); BS: NC with the inclusion of 500 g ton-1 of GutCare® (Bacillus subtilis - DSM 32315). Diets used maize-soybean meal in a three-phase plan. Broiler chickens on the BA and BS diets had higher feed consumption, body weight gain, and improved feed conversion efficiency at 28 and 42 d when compared to the birds in the negative control. Broiler chickens fed PC, BA, and BS diets had a higher villus height and absorption area in the jejunum at 28 d, compared to the birds in the negative control. There was more butyric acid production by the intestinal microbiota at 28 d of age in broilers on the BA diet. Supplementing with 1000 g/ton of BA and 500 g/ton of BS effectively substituted the 8% enramycin antibiotic, enhancing broiler growth during an induced intestinal challenge.

ABSTRACT Hepatic injuries in COVID-19 are not yet fully understood and indirect pathways (without viral replication in the liver) have been associated with the activation of vascular mechanisms of liver injury in humans infected with SARS-CoV-2. Golden Syrian hamsters are an effective model for experimental reproduction of moderate and self-limiting lung disease during SARS-CoV-2 infection. As observed in humans, this experimental model reproduces lesions of bronchointerstitial pneumonia and pulmonary vascular lesions, including endotheliitis (attachment of lymphoid cells to the luminal surface of endothelium). Extrapulmonary vascular lesions are well documented in COVID-19, but such extrapulmonary vascular lesions have not yet been described in the Golden Syrian hamster model of SARS-CoV-2 infection. The study aimed to evaluate microscopic liver lesions in Golden Syrian hamsters experimentally infected with SARS-CoV-2. In total, 38 conventional Golden Syrian hamsters, divided into infected group (n=24) and mock-infected group (n=14), were euthanized at 2-, 3-, 4-, 5-, 7-, 14-, and 15-days post infection with SARS-CoV-2. Liver fragments were evaluated by histopathology and immunohistochemical detection of SARS-CoV-2 Spike S2 antigens. The frequencies of portal vein endotheliitis, lobular activity, hepatocellular degeneration, and lobular vascular changes were higher among SARS-CoV-2-infected animals. Spike S2 antigen was not detected in liver. The main results indicate that SARS-CoV-2 infection exacerbated vascular and inflammatory lesions in the liver of hamsters with pre-existing hepatitis of unknown origin. A potential application of this animal model in studies of the pathogenesis and evolution of liver lesions associated with SARS-CoV-2 infection still needs further evaluation. COVID19 COVID 19 COVID-1 without SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2. 2 selflimiting self limiting SARS-CoV- attachment endothelium. endothelium . endothelium) COVID19, 19, total 3 n=24 n24 n 24 (n=24 mockinfected mock n=14, n14 n=14 , 14 (n=14) 2, 2- 3, 3- 4, 4 4- 5, 5 5- 7, 7 7- 14, 14- 15days days 15 S antigens activity degeneration SARSCoV2infected SARSCoVinfected animals preexisting pre existing origin evaluation COVID1 1 COVID- SARS-CoV n=2 n2 (n=2 n1 n=1 (n=14 n= (n= (n=1 (n