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Progression of valve heart disease in a cohort of patients undergoing renal replacement therapy
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Tompson, Maria Eduarda Cavalcanti
; Pimentel, José Arthur Viana de Oliveira
; Silva, Manuella de Amorim
; Santos-Veloso, Marcelo Antônio Oliveira
; Lordsleem, Andrea Bezerra de Melo da Silveira
; Lima, Sandro Gonçalves de
.
Resumo Introdução: Doenças cardiovasculares são uma causa significativa de morte em pacientes com Doença Renal Crônica (DRC). A calcificação valvar é preditor de mortalidade cardiovascular e doença arterial coronariana. Objetivo: Avaliar a frequência, fatores associados e progressão de valvopatias em pacientes com DRC. Métodos: Coorte retrospectiva com 291 pacientes ambulatoriais no Hospital das Clínicas de Pernambuco. Inclusão: ≥18 anos com DRC e valvopatia; exclusão: tratamento conservador ou dados incompletos. Variáveis clínicas e laboratoriais foram comparadas e categorizadas por tempo de terapia dialítica (TTD): <5 anos, 5–10 anos, >10 anos. Foram aplicados os testes Qui-quadrado, exato de Fisher, ANOVA, Kruskal-Wallis. Associação entre valvopatia e TTD foi avaliada por regressão binária. Significância foi definida como p < 0,05. Resultados: A valvopatia mitral foi encontrada em 82,5% (240) dos casos, seguida da aórtica (65,6%; 86). Houve progressão da doença valvar em 106 (36,4%) pacientes. Não houve associação entre valvopatias aórtica, pulmonar, mitral ou tricúspide e TTD. Hiperparatireoidismo secundário foi a única variável explicativa significativa na regressão para valvopatia mitral (OR 2,59 [IC95%: 1,09–6,18]; p = 0,031). Conclusão: Encontramos alta frequência de valvopatias, especialmente mitral e aórtica, aem pacientes com DRC. Não houve associação entre TTD e valvopatia. Introdução . (DRC) coronariana Objetivo Métodos 29 Pernambuco Inclusão 18 ≥1 exclusão incompletos (TTD) 5 510 10 5–1 >1 Quiquadrado, Quiquadrado Qui quadrado, quadrado Qui-quadrado Fisher ANOVA KruskalWallis. KruskalWallis Kruskal Wallis. Wallis Kruskal-Wallis binária 005 0 05 0,05 Resultados 825 82 82,5 240 (240 casos 65,6% 656 65 6 (65,6% 86. 86 86) 36,4% 364 36 4 (36,4% pulmonar OR 259 2 59 2,5 IC95% IC95 IC [IC95% 1,09–6,18 109618 1 09 1,09–6,18] 0,031. 0031 0,031 031 0,031) Conclusão (DRC ≥ (TTD 51 5– > 00 0,0 8 82, 24 (24 65,6 (65,6 36,4 3 (36,4 25 2, IC9 [IC95 1,09–6,1 10961 003 0,03 03 0, (2 65, (65, 36, (36, [IC9 1,09–6, 1096 ( (65 (36 [IC 1,09–6 109 (6 (3 1,09– 1,09 1,0 1,
Abstract Introduction: Cardiovascular disease is an important cause of death among patients with chronic kidney disease (CKD). Valve calcification is a predictor of cardiovascular mortality and coronary artery disease. Objective: To assess heart valve disease frequency, associated factors, and progression in CKD patients. Methods: We conducted a retrospective study on 291 CKD patients at Hospital das Clínicas de Pernambuco. Inclusion criteria were age ≥ 18 with CKD and valve disease, while those on conservative management or with missing data were excluded. Clinical and laboratory variables were compared, and patients were categorized by dialysis duration (<5 years; 5–10 years; >10 years). Statistical tests, including chi-square, Fisher’s exact, ANOVA, and Kruskal-Wallis, were employed as needed. Simple and multivariate binary regression models were used to analyze valve disease associations with dialysis duration. Significance was defined as p < 0.05. Results: Mitral valve disease was present in 82.5% (240) of patients, followed by aortic valve disease (65.6%; 86). Over time, 106 (36.4%) patients developed valve disease. No significant association was found between aortic, pulmonary, mitral, or tricuspid valve disease and dialysis duration. Secondary hyperparathyroidism was the sole statistically significant factor for mitral valve disease in the regression model (OR 2.59 [95% CI: 1.09–6.18]; p = 0.031). Conclusion: CKD patients on renal replacement therapy exhibit a high frequency of valve disease, particularly mitral and aortic valve disease. However, no link was established between dialysis duration and valve disease occurrence or progression. Introduction CKD. . (CKD) Objective factors Methods 29 Pernambuco 1 excluded compared <5 5 (< years 510 10 5–1 >1 years. years) tests chisquare, chisquare chi square, square chi-square Fishers Fisher s exact ANOVA KruskalWallis, KruskalWallis Kruskal Wallis, Wallis Kruskal-Wallis needed 005 0 05 0.05 Results 825 82 82.5 240 (240 65.6% 656 65 6 (65.6% 86. 86 86) time 36.4% 364 36 4 (36.4% pulmonary OR 259 2 59 2.5 95% 95 [95 CI 1.09–6.18 109618 09 1.09–6.18] 0.031. 0031 0.031 031 0.031) Conclusion However (CKD ( 51 5– > 00 0.0 8 82. 24 (24 65.6 (65.6 36.4 3 (36.4 25 2. 9 [9 1.09–6.1 10961 003 0.03 03 0. (2 65. (65. 36. (36. [ 1.09–6. 1096 (65 (36 1.09–6 109 (6 (3 1.09– 1.09 1.0 1.
2.
Efeitos da campanha de vacinação nas internações e mortalidade relacionados ao sarampo no Brasil na última década
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Loureiro, Amanda Aparecida Ribeiro
; Dutra, Hadassa Franca
; Gonçalves, Eduarda Berberth Dias
; Pereira, Francisco Otávio Silveira
; Argolo, Breno Mendes
; Fonseca, Raquel Maria da
; Fófano, Gisele Aparecida
.
Resumo O sarampo é uma das principais causas de morbidade e mortalidade na população pediátrica e pode ser prevenido com 100% de eficácia pela vacinação. No entanto, a doença permanece ativa no território brasileiro. O objetivo do artigo é avaliar a adesão da população à vacinação e a possível relação com hospitalização e mortalidade em relação ao sarampo no Brasil. Trata-se de um estudo ecológico realizado a partir de dados secundários de mortalidade e internações acerca do sarampo e da cobertura vacinal contra a doença no Brasil nos anos de 2013 a 2022. O ápice de adesão ao calendário vacinal contra o sarampo se deu nos três anos que precederam a erradicação da doença no país, ocorrida em 2016. Nesse intervalo, tem-se as menores taxas de internação, com a mortalidade zerada de 2014 a 2017. Em contrapartida, verifica-se, desde então, queda na taxas de vacinação, acentuadas a partir de 2019, quando a doença reaparece no Brasil. Concomitantemente, as taxas de internação e mortalidade atingem os valores mais altos registrados. A adesão populacional ao calendário vacinal completo contra o sarampo, essencial ao controle da doença e dos óbitos relacionados, está insuficiente, o que se reflete nas taxas de internações e mortalidade.
Abstract Measles is one of the main causes of morbidity and mortality in the pediatric population and it can be prevented with 100% effectiveness by vaccination. However, the disease remains active in throughout Brazil. The scope of this article is to evaluate the population’s adherence to vaccination and the potential connection with hospitalizations and mortality in relation to measles in Brazil. This is an ecological study based on secondary data on mortality and hospitalizations due to measles and vaccination coverage against the disease in Brazil from 2013 to 2022. The peak of adherence to the measles vaccination schedule occurred in the 3 years that preceded the eradication of the disease in the country, which occurred in 2016. In this interval, there are the lowest hospitalization rates, with zero mortality from 2014 to 2017. On the other hand, there has been a marked drop in vaccination rates since 2019, when the disease resurfaced in Brazil. Concomitantly, hospitalization and mortality rates reach the highest recorded values. Population adherence to the complete measles vaccination schedule, which is essential to control the disease and related deaths, is insufficient, which is reflected in hospitalization and mortality rates.
3.
Difference Between Cardiopulmonary Bypass Time and Aortic Cross-Clamping Time as a Predictor of Complications After Coronary Artery Bypass Grafting CrossClamping Cross Clamping
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Jucá, Fabiano Gonçalves
; Freitas, Fabiane Letícia de
; Goncharov, Maxim
; Pes, Daniella de Lima
; Jucá, Maria Eduarda Coimbra
; Dallan, Luis Roberto Palma
; Lisboa, Luiz Augusto Ferreira
; Jatene, Fábio B.
; Mejia, Omar Asdrúbal Vilca
.
Brazilian Journal of Cardiovascular Surgery
- Métricas do periódico
ABSTRACT Introduction: Along with cardiopulmonary bypass time, aortic cross-clamping time is directly related to the risk of complications after heart surgery. The influence of the time difference between cardiopulmonary bypass and cross-clamping times (TDC-C) remains poorly understood. Objective: To assess the impact of cardiopulmonary bypass time in relation to cross-clamping time on immediate results after coronary artery bypass grafting in the Registro Paulista de Cirurgia Cardiovascular (REPLICCAR) II. Methods: Analysis of 3,090 patients included in REPLICCAR II database was performed. The Society of Thoracic Surgeons outcomes were evaluated (mortality, kidney failure, deep wound infection, reoperation, cerebrovascular accident, and prolonged ventilation time). A cutoff point was adopted, from which the increase of this difference would affect each outcome. Results: After a cutoff point determination, all patients were divided into Group 1 (cardiopulmonary bypass time < 140 min., TDC-C < 30 min.), Group 2 (cardiopulmonary bypass time < 140 min., TDC-C > 30 min.), Group 3 (cardiopulmonary bypass time > 140 min., TDC-C < 30 min.), and Group 4 (cardiopulmonary bypass time > 140 min., TDC-C > 30 min.). After univariate logistic regression, Group 2 showed significant association with reoperation (odds ratio: 1.64, 95% confidence interval: 1.01-2.66), stroke (odds ratio: 3.85, 95% confidence interval: 1.99-7.63), kidney failure (odds ratio: 1.90, 95% confidence interval: 1.32-2.74), and in-hospital mortality (odds ratio: 2.17, 95% confidence interval: 1.30-3.60). Conclusion: TDC-C serves as a predictive factor for complications following coronary artery bypass grafting. We strongly recommend that future studies incorporate this metric to improve the prediction of complications. Introduction crossclamping cross clamping surgery TDCC TDC C (TDC-C understood Objective (REPLICCAR Methods 3090 090 3,09 performed mortality, (mortality infection accident time. . time) adopted outcome Results determination 14 min min. , min.) min.. regression odds ratio 164 64 1.64 95 interval 1.012.66, 101266 1.01 2.66 01 66 1.01-2.66) 385 85 3.85 1.997.63, 199763 1.99 7.63 99 7 63 1.99-7.63) 190 90 1.90 1.322.74, 132274 1.32 2.74 32 74 1.32-2.74) inhospital hospital 217 17 2.17 1.303.60. 130360 1.30 3.60 60 1.30-3.60) Conclusion 309 09 3,0 16 6 1.6 9 012 1.012.66 10126 101 1.0 266 2.6 0 1.01-2.66 38 8 3.8 997 1.997.63 19976 199 1.9 763 7.6 1.99-7.63 19 322 1.322.74 13227 132 1.3 274 2.7 1.32-2.74 21 2.1 303 1.303.60 13036 130 360 3.6 1.30-3.60 3, 1. 1.012.6 1012 10 26 2. 1.01-2.6 3. 1.997.6 1997 76 7. 1.99-7.6 1.322.7 1322 13 27 1.32-2.7 1.303.6 1303 36 1.30-3.6 1.012. 1.01-2. 1.997. 1.99-7. 1.322. 1.32-2. 1.303. 1.30-3. 1.012 1.01-2 1.997 1.99-7 1.322 1.32-2 1.303 1.30-3 1.01- 1.99- 1.32- 1.30-
4.
Efeitos da campanha de vacinação nas internações e mortalidade relacionados ao sarampo no Brasil na última década
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Loureiro, Amanda Aparecida Ribeiro
; Dutra, Hadassa Franca
; Gonçalves, Eduarda Berberth Dias
; Pereira, Francisco Otávio Silveira
; Argolo, Breno Mendes
; Fonseca, Raquel Maria da
; Fófano, Gisele Aparecida
.
Resumo O sarampo é uma das principais causas de morbidade e mortalidade na população pediátrica e pode ser prevenido com 100% de eficácia pela vacinação. No entanto, a doença permanece ativa no território brasileiro. O objetivo do artigo é avaliar a adesão da população à vacinação e a possível relação com hospitalização e mortalidade em relação ao sarampo no Brasil. Trata-se de um estudo ecológico realizado a partir de dados secundários de mortalidade e internações acerca do sarampo e da cobertura vacinal contra a doença no Brasil nos anos de 2013 a 2022. O ápice de adesão ao calendário vacinal contra o sarampo se deu nos três anos que precederam a erradicação da doença no país, ocorrida em 2016. Nesse intervalo, tem-se as menores taxas de internação, com a mortalidade zerada de 2014 a 2017. Em contrapartida, verifica-se, desde então, queda na taxas de vacinação, acentuadas a partir de 2019, quando a doença reaparece no Brasil. Concomitantemente, as taxas de internação e mortalidade atingem os valores mais altos registrados. A adesão populacional ao calendário vacinal completo contra o sarampo, essencial ao controle da doença e dos óbitos relacionados, está insuficiente, o que se reflete nas taxas de internações e mortalidade. 100 entanto brasileiro Tratase Trata 201 2022 país 2016 intervalo temse tem 2017 contrapartida verificase, verificase verifica se, verifica-se então 2019 Concomitantemente registrados relacionados insuficiente 10 20 202 1 2
Abstract Measles is one of the main causes of morbidity and mortality in the pediatric population and it can be prevented with 100% effectiveness by vaccination. However, the disease remains active in throughout Brazil. The scope of this article is to evaluate the population’s adherence to vaccination and the potential connection with hospitalizations and mortality in relation to measles in Brazil. This is an ecological study based on secondary data on mortality and hospitalizations due to measles and vaccination coverage against the disease in Brazil from 2013 to 2022. The peak of adherence to the measles vaccination schedule occurred in the 3 years that preceded the eradication of the disease in the country, which occurred in 2016. In this interval, there are the lowest hospitalization rates, with zero mortality from 2014 to 2017. On the other hand, there has been a marked drop in vaccination rates since 2019, when the disease resurfaced in Brazil. Concomitantly, hospitalization and mortality rates reach the highest recorded values. Population adherence to the complete measles vaccination schedule, which is essential to control the disease and related deaths, is insufficient, which is reflected in hospitalization and mortality rates. 100 However populations s 201 2022 country 2016 interval 2017 hand 2019 Concomitantly values deaths insufficient 10 20 202 1 2
5.
Donor mothers portrayal and associated variables with breast milk donation in a Human Milk Bank
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Vieira, Ana Clara
; Duda, Maria Eduarda Holzer
; Abreu, Isabella Schroeder
; Schiessel, Dalton Luiz
; Vieira, Daniele Gonçalves
; Saldan, Paula Chuproski
.
RESUMO Objetivos Descrever e analisar o perfil de mães doadoras e as variáveis associadas à doação de leite materno em um Banco de Leite Humano no município de Guarapuava, Paraná, Brasil. Métodos Trata-se de um estudo transversal obtido a partir de informações constantes no formulário de cadastro de doadoras entre o período de julho de 2013 (implementação do serviço) até o mês de dezembro de 2019. Os dados coletados foram tabulados e posteriormente foi feita a análise descritiva das variáveis e testes de associação do Qui-quadrado e exato de Fischer. Resultados Das 1.491 fichas analisadas, a presente pesquisa identificou que 70,73% das doadoras tinham entre 20 e 34 anos de idade; 67,69% realizaram o pré-natal na rede pública de saúde e 61,37% realizaram parto cesárea. A maioria das mães, 61,44%, permaneceu como doadora por 29 dias e 53,83% delas doaram o volume de até 500ml de leite. Além disso, observou-se associação estatisticamente significativa entre o volume de leite doado e o tempo de doação para as seguintes variáveis: local de realização do pré-natal, idade gestacional, peso ao nascer, idade da criança e tabagismo. A idade materna se associou ao maior volume de leite doado. Conclusão Os achados do estudo reforçam a importância da abordagem ainda no pré-natal sobre a possibilidade de doação de leite humano, com ênfase no serviço privado de saúde, e, em toda a rede de atenção à saúde da mulher e da criança, bem como na comunidade. Guarapuava Paraná Brasil Tratase Trata 201 implementação 2019 Quiquadrado Qui quadrado Fischer 1491 1 491 1.49 analisadas 7073 70 73 70,73 2 3 6769 67 69 67,69 prénatal pré natal 6137 61 37 61,37 cesárea 6144 44 61,44% 5383 53 83 53,83 ml disso observouse observou prénatal, natal, gestacional nascer tabagismo humano comunidade 149 49 1.4 707 7 70,7 676 6 67,6 613 61,3 614 4 61,44 538 5 8 53,8 14 1. 70, 67, 61, 61,4 53,
ABSTRACT Objective To describe and analyze the donor mothers’ profile and variables associated with breast milk donation at Human Milk Bank in the municipality of Guarapuava, Paraná, Brazil. Methods This was a cross-sectional study obtained from information contained in the donor registration form between the period July 2013 (implementation of the service) to December 2019. The collected data were tabulated and descriptive analysis of variables and Chi-square and Fischer’s exact association tests were performed. Results Of 1,491 records analyzed, this research identified that 70.73% of donors were between 20 to 34 years old; 67.69% had prenatal care at public health network and 61.37% have had cesarean delivery. Most mothers (61.44%) remained as donor for 29 days and 53.83% of them donated up to 500 ml of milk. In addition, statistically significant association was observed between milk volume donated and donation time for the following variables: prenatal place care, gestational age, child's birth weight, child age, and smoking. Maternal age was associated with a higher volume of donated milk. Conclusion The study's findings reinforce the approaching importance the possibility of human milk donation during prenatal care, with emphasis on private health service, and throughout the women's and children's health care network, as well as on the community. Guarapuava Paraná Brazil crosssectional cross sectional 201 implementation service 2019 Chisquare Chi square Fischers Fischer s performed 1491 1 491 1,49 analyzed 7073 70 73 70.73 2 3 old 6769 67 69 67.69 6137 61 37 61.37 delivery 61.44% 6144 44 (61.44% 5383 53 83 53.83 50 addition childs weight smoking studys womens women childrens children community 149 49 1,4 707 7 70.7 676 6 67.6 613 61.3 61.44 614 4 (61.44 538 5 8 53.8 14 1, 70. 67. 61. 61.4 (61.4 53. (61. (61 (6 (
6.
Referrals for rheumatologic evaluation following a positive antinuclear antibody test result. A cross-sectional single center Brazilian study result crosssectional cross sectional
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Vecchia, Leonardo Borgato Della
; Assis, Caio Delano Campos Oliveira
; Salatiel, Fernando de Oliveira
; Cirino, Maria Thereza Santos
; Scarpante, Maria Eduarda Vogel
; Oliveira, Vanessa Monteiro
; Meneghin, Letícia Pedroso
; Silva, Maria Júlia Gonçalves
; Santos, Victória Ferini dos
; Catardo, Natália Pavoni
; Nemesio, Isabela Pulini
; Paula, Lívia Loamí Ruyz Jorge de
; Sasdelli, Carolina Borges Garcia
; Bacchiega, Ana Beatriz Santos
.
Abstract Background In general, patients are referred for rheumatological evaluation due to isolated laboratory abnormalities, especially antinuclear antibody (ANA) positivity, with the risk of more severe patients remaining on the waiting list for longer than desired. The aim of this study was to analyze the demographic, clinical, and laboratory information of patients referred to a specialized rheumatological care unit because of positive antinuclear antibody. Methods This is a retrospective study of 99 out of 1670 patients seen by the same rheumatologist between 01/01/2011 and 01/01/2019. Patients whose referrals were exclusively due to the ANA test result and the specialist’s final diagnosis being “abnormal finding of serum immunological test” (ICD-10 R769) were included. Sociodemographic, clinical, and laboratory information were extracted from the consulting rheumatologist’s chart. Descriptive statistics were used for data analysis. Results A total of 99 patients were included, most of whom were female (84.8%) with a median age of 49 years. At the moment of specialist’s appointment, 97 patients (97.9%) repeated the ANA test, and 77 patients remained positive. Of these, only 35 (35.35%) were in a high titer range (greater than or equal to 1:320). Complete blood count for cytopenia’s investigation was not performed in a high percentage of patients (22.2%), as well as urinalysis (31.3%). In addition, more than 70% of patients score 0 to 1 classification criteria for Systemic Lupus Erythematosus, according to SLE - ACR 1987 (American College of Rheumatology) and SLICC 2012 (Systemic Lupus International Collaborating Clinics). Conclusions Most patients are still referred for specialized evaluation due to the misinterpretation of laboratory tests that were inappropriately requested in patients without clinical evidence of autoimmune rheumatic disease. general abnormalities (ANA positivity desired demographic 9 167 01012011 01 2011 01/01/201 01012019 2019 01/01/2019 specialists specialist s abnormal ICD10 ICD 10 (ICD-1 R769 R included Sociodemographic rheumatologists chart analysis 84.8% 848 84 8 (84.8% 4 years appointment 97.9% 979 (97.9% 7 these 3 35.35% 3535 (35.35% greater 1320. 1320 320 . 1:320) cytopenias cytopenia 22.2%, 222 22.2% , 22 2 (22.2%) 31.3%. 313 31.3% 31 (31.3%) addition 70 Erythematosus 198 American Rheumatology 201 Clinics. Clinics Clinics) disease 16 0101201 01/01/20 ICD1 (ICD- R76 84.8 (84.8 97.9 (97.9 35.35 353 (35.35 132 32 1:320 22.2 (22.2% 31.3 (31.3% 19 20 010120 01/01/2 (ICD R7 84. (84. 97. (97. 35.3 (35.3 13 1:32 22. (22.2 31. (31.3 01012 01/01/ (84 (97 35. (35. 1:3 (22. (31. 0101 01/01 (8 (9 (35 1: (22 (31 010 01/0 ( (3 (2 01/
7.
Assessing proteases and enzymes of the trypanothione system in subpopulations of Leishmania (Viannia) braziliensis Thor strain during macrophage infection Viannia (Viannia
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Albuquerque-Melo, Barbara Cristina de
; Pereira, Bernardo Acácio Santini
; Ennes-Vidal, Vítor
; Gonçalves, Maria Eduarda Pinto
; Côrtes, Luzia Monteiro de Castro
; Cysne-Finkelstein, Léa
; Guedes, Herbert Leonel de Matos
; Dias-Lopes, Geovane
; Alves, Carlos Roberto
.
BACKGROUND Leishmania (Viannia) braziliensis Thor strain exhibits a heterogeneous composition comprised of subpopulations with varying levels of infectivity. Clonal subpopulations were previously obtained from the strain Thor by sorting single-parasites and proceeding cultivation. The subpopulations used in this study are named Thor03, Thor 10 and Thor22. OBJECTIVES Phenotypic characteristics of the parasite, specially focusing on virulence factors and resistance to the antimicrobial mechanisms of macrophages, were investigate in these subpopulations. METHODS Cellular and molecular biology, as well as biochemistry approaches were applied to obtain the data analysed in this study. FINDINGS Relative quantification of gene expression was measured for calpain, cysteine protease B (CPB), and subtilisin proteases but no significant differences in these genes’ expression among subpopulations was observed. However, subtilisin and CPB proteins were assessed as more abundant in Thor03 by fluorescence-labelled flow cytometry technique. Western Blotting assays, as semi-quantitative analysis in gel, showed higher concentrations of subtilisin (110 to 50 kDa) and CPB (40 to 18 kDa) in extract of intracellular amastigotes from subpopulations Thor03 and Thor10 and calpain (60 to 25 kDa) showed no significant differences among subpopulations. Complementary, higher trypanothione reductase activity was observed in Thor10 intracellular amastigotes and assays of susceptibility to hydrogen peroxide-inducing agents and nitric oxide donors conducted with promastigotes revealed greater resistance to in vitro oxidative stress induction for Thor10, followed by Thor03. MAIN CONCLUSIONS The data obtained for the virulence factors explored here suggest how multiple coexisting phenotypic-distinct subpopulations may contribute in adaptability of a single L. (V.) braziliensis strain during infection in the host cells. Viannia (Viannia infectivity singleparasites parasites cultivation 1 Thor22 parasite macrophages biology CPB, , (CPB) genes However Thor0 fluorescencelabelled fluorescence labelled technique semiquantitative semi quantitative gel 110 (11 5 kDa 40 (4 Thor1 60 (6 2 Complementary peroxideinducing peroxide inducing phenotypicdistinct phenotypic distinct L V. V (V. cells Thor2 (CPB 11 (1 4 ( 6 (V
8.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
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; Biffi, Gabriel
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; Oliveira, Ismael B. de
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; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
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; Silva, Rafael A.P.F.
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; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
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; Caires, Rodrigo A.
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; Dios, Rodrigo de V.P.
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; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
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; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
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; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
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; Paiva, Sandra V.
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; Costa, Sávio C.
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ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
9.
Home care service for children/adolescents with special health care needs: family perception childrenadolescents children adolescents needs
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Lima, Paloma Mayara Vieira de Macena
; Fernandes, Leiliane Teixeira Bento
; Santos, Mariana Matias
; Cavalcante, Maria Eduarda Pires Lima
; Neves, Eliane Tatsch
; Toso, Beatriz Rosana Gonçalves de Oliveira
; Collet, Neusa
; Vaz, Elenice Maria Cecchetti
.
RESUMO Objetivo: Apreender a percepção da família acerca dos cuidados prestados pelos serviços de atenção domiciliar a crianças e adolescentes com necessidades de saúde especiais. Método: Estudo qualitativo, exploratório-descritivo, realizado com 15 familiares de crianças e adolescentes com necessidades de saúde especiais atendidos por Serviços de Atenção Domiciliar de sete municípios da Paraíba, Brasil, em 2021, selecionados de nove municípios identificados por estudos prévios. Os dados foram coletados com uso de entrevista semiestruturada realizada remotamente por meio de ligações telefônicas. O material empírico foi submetido à Análise Temática Indutiva e interpretado à luz do conceito de vulnerabilidade em saúde. Resultados: Os Serviços de Atenção Domiciliar minimizam as vulnerabilidades em saúde dessas crianças e adolescentes e seus familiares à medida que facilitam o acesso às ações e serviços da Rede de Atenção à Saúde, prestam um cuidado humanizado e centrado na promoção da saúde e fortalecimento de vínculos, bem como, facilitam a tomada de decisão familiar em domicílio quanto às necessidades de saúde dos usuários. Considerações finais: As ações desses serviços permeiam o cotidiano familiar, possibilitando a ampliação das práticas de cuidados aos familiares/cuidadores considerando suas limitações e melhora da articulação das Redes de Atenção à Saúde para garantir um cuidado integral. Objetivo Método qualitativo exploratóriodescritivo, exploratóriodescritivo exploratório descritivo, descritivo exploratório-descritivo 1 Paraíba Brasil 2021 prévios telefônicas Resultados vínculos como usuários finais familiarescuidadores cuidadores integral 202 20 2
ABSTRACT Objective: To apprehend the family's perception of the care provided by home care services to children and adolescents with special health needs. Method: Qualitative, exploratory-descriptive study, carried out with 15 family members of children and adolescents with special health needs served by Home Care Services in seven municipalities in Paraíba, in 2021, selected from nine municipalities identified by previous studies. Data were collected using semi-structured interviews carried out remotely through telephone calls. The empirical material was subjected to Inductive Thematic Analysis and interpreted in light of the concept of health vulnerability. Results: The Home Care Services facilitate minimize the health vulnerabilities of these children and adolescents and their families as they facilitate access to the actions and services of the Health Care Network, provide humanized care focused on promoting health and strengthening bonds, as well as how, they facilitate family decision-making at home regarding users' health needs. Final considerations: The actions of these services permeate family daily life, enabling the expansion of care practices for family members/caregivers considering their limitations and improving the coordination of Health Care Networks to guarantee comprehensive care. Objective familys s Method Qualitative exploratorydescriptive exploratory descriptive study 1 Paraíba 2021 studies semistructured semi structured calls vulnerability Results Network bonds how decisionmaking decision making users considerations life memberscaregivers caregivers 202 20 2
RESUMEN Objetivo: Conocer la percepción de la familia sobre la atención prestada por los servicios de atención domiciliaria a niños/adolescentes con necesidades especiales de salud. Método: Estudio cualitativo, exploratorio-descriptivo, realizado con 15 familiares de niños y adolescentes con necesidades especiales de salud atendidos por Servicios de Atención Domiciliaria en siete municipios de Paraíba, en 2021, seleccionados entre nueve municipios identificados por estudios previos. Los datos fueron recolectados mediante entrevistas semiestructuradas realizadas de forma remota a través de llamadas telefónicas. El material empírico fue sometido a Análisis Temático Inductivo e interpretado a la luz del concepto de vulnerabilidad en salud. Resultados: Los Servicios de Atención Domiciliaria minimizan las vulnerabilidades en salud de estos niños, niñas y adolescentes y sus familias, ya que facilitan el acceso a las acciones y servicios de la Red de Atención en Salud, brindan una atención humanizada enfocada a promover la salud y fortalecer los vínculos, además de facilitar la decisión familiar. -hacer en casa teniendo en cuenta las necesidades de salud de los usuarios. Consideraciones finales: Las acciones de estos servicios permean el cotidiano familiar, permitiendo ampliar las prácticas de cuidado a los familiares/cuidadores considerando sus limitaciones y mejorando la coordinación de las Redes de Atención en Salud para garantizar una atención integral. Objetivo niñosadolescentes Método cualitativo exploratoriodescriptivo, exploratoriodescriptivo exploratorio descriptivo, descriptivo exploratorio-descriptivo 1 Paraíba 2021 previos telefónicas Resultados familias vínculos familiar hacer usuarios finales familiarescuidadores cuidadores integral 202 20 2
10.
A economia política do mundo contemporâneo: revisitando um campo multidisciplinar
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11.
Biomechanical evaluation of four surgical techniques for ventral stabilization of the atlantoaxial joint in dogs
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Ferreira, Danyelle Rayssa Cintra
; Dias, Luís Gustavo Gosuen Gonçalves
; Minto, Bruno Watanabe
; Rocha, Thiago André Salvitti de Sá
; Malta, Caio Afonso dos Santos
; Conceição, Maria Eduarda Bastos Andrade Moutinho da
; Lucena, Dayvid Vianêis Farias de
.
ABSTRACT Purpose: This study compared, through biomechanical evaluation under ventral flexion load, four surgical techniques for ventral stabilization of the atlantoaxial joint in dogs. Methods: In total, 28 identical atlantoaxial joint models were created by digital printing from computed tomography images of a dog, and the specimens were divided into four groups of seven. In each group, a different technique for ventral stabilization of the atlantoaxial joint was performed: transarticular lag screws, polyaxial screws, multiple screws and bone cement (polymethylmethacrylate–PMMA), and atlantoaxial plate. After the stabilization technique, biomechanical evaluation was performed under ventral flexion load, both with a predefined constant load and with a gradually increasing load until stabilization failure. Results: All specimens, regardless of stabilization technique, were able to support the predefined load without failing. However, the PMMA method provided significant more rigidity (p ≤ 0.05) and also best resisted the gradual increase in load, supporting a significantly higher maximum force (p ≤ 0.05). There was no statistical difference in flexural strength between the transarticular lag screws and plate groups. The polyaxial screws method was significantly less resistant to loading (p ≤ 0.05) than the other groups. Conclusions: The PMMA technique had biomechanical advantages in ventral atlantoaxial stabilization over the other evaluated methods. Purpose compared dogs Methods total 2 dog seven group polymethylmethacrylate–PMMA, polymethylmethacrylatePMMA polymethylmethacrylate–PMMA , polymethylmethacrylate (polymethylmethacrylate–PMMA) failure Results failing However p 0.05 005 0 05 0.05. . Conclusions methods (polymethylmethacrylate–PMMA 0.0 00 0.
12.
Thermal comfort and productive responses of 7/8 holstein-gyr cows subjected to cooling system 78 7 8 7/ holsteingyr holstein gyr
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Silva, Marcos Vinícius da
; Almeida, Gledson Luiz Pontes de
; Pandorfi, Héliton
; Moraes, Alex Souza
; Macêdo, Gleidiana Amélia Pontes de Almeida
; Oliveira, Maria Eduarda Gonçalves de
; Melo, Maria Vitória Neves de
; Santana, Taize Calvacante
.
ABSTRACT. The objective of this research was to identify the influence of the evaporative adiabatic cooling system (EACS) on the thermal comfort and productive responses of dairy cattle, through multivariate analysis by principal components (PC), in the summer and winter seasons of the semiarid region of Pernambuco, Brazil. The data came from an experiment that included 16 multiparous lactating cows (7/8 Holstein-Gyr), randomly distributed in 4 sets, with 4 experimental phases and 4 treatments (0, 10, 20, and 30 min.). The multivariate analysis was carried out through PC for the thermal comfort indices, physiological variables, and milk production and composition. The highest milk production in the summer season was obtained for animals exposed to the cooling system for 30 min. In the winter season in the morning period, the use of the EACS for 10 min. was sufficient for improvements in milk production. The times of exposure to EACS caused changes in the composition of milk, for both seasons. Principal component analysis made it possible to verify a positive correlation of evaporative cooling with thermal comfort, physiological responses, and production and composition of milk of lactating cows. ABSTRACT (EACS cattle PC, , (PC) Pernambuco Brazil 1 7/8 78 7 8 (7/ HolsteinGyr, HolsteinGyr Holstein Gyr Holstein-Gyr) sets 0, 0 (0 20 3 min.. min . min.) indices variables period (PC 7/ (7 Holstein-Gyr ( 2
13.
Genome-wide identification and evolutionary view of ALOG gene family in Solanaceae Genomewide Genome wide
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Turchetto, Caroline
; Silvério, Ariadne de Castro
; Waschburger, Edgar Luis
; Lacerda, Maria Eduarda Gonçalves
; Quintana, Isadora Vieira
; Turchetto-Zolet, Andreia Carina
.
Abstract The ALOG gene family, which was named after its earliest identified members ( Arabidopsis LSH1 and Oryza G1), encodes a class of transcription factors (TF) characterized by the presence of a highly conserved ALOG domain. These proteins are found in various plant species playing regulatory roles in plant growth, development, and morphological diversification of inflorescence. The functional characterization of these genes in some plant species has demonstrated their involvement in floral architecture. In this study, we used a genome-wide and phylogenetic approach to gain insights into plants’ origin, diversification, and functional aspects of the ALOG gene family. In total, 648 ALOG homologous genes were identified in 77 Viridiplantae species, and their evolutionary relationships were inferred using maximum likelihood phylogenetic analyses. Our results suggested that the ALOG gene family underwent several rounds of gene duplication and diversification during angiosperm evolution. Furthermore, we found three functional orthologous groups in Solanaceae species. The study provides insights into the evolutionary history and functional diversification of the ALOG gene family, which could aid in understanding the mechanisms underlying floral architecture in angiosperms. LSH G1, G1 G , G1) TF (TF domain growth development inflorescence genomewide genome wide plants origin total 64 7 analyses evolution Furthermore angiosperms 6
14.
Thoracoscopy pulmonary biopsy by two portals with a novel pre-tied loop ligature device in rabbits: an experimental study pretied pre tied rabbits
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Wittmaack, Monica Carolina Nery
; Sembenelli, Guilherme
; Conceição, Maria Eduarda Bastos Andrade Moutinho da
; Montanhim, Gabriel Luiz
; Crivellaro, Roberta Martins
; Rolemberg, Daniele Santos
; Dias, Luis Gustavo Gosuen Gonçalves
; Silva, Marco Augusto Machado da
; Teixeira, Pedro Paulo Maia
; Moraes, Paola Castro
.
RESUMO: A toracoscopia está substituindo as biópsias pulmonares abertas por ser menos invasiva. Usualmente a técnica é feita utilizando três portais e ligaduras feitas intra corporalmente. O objetivo deste estudo foi descrever a viabilidade e eficácia de uma nova ligadura com alça pré-amarrada e propor uma estratégia de acesso toracoscópico com dois portais para realizar biópsia pulmonar em pacientes com menos de 5kg. Dez coelhos foram posicionados em decúbito dorsal. A biópsia pulmonar por toracoscopia total foi feita pela abordagem combinada transdiafragmática e abordagem intercostal direita. Uma nova ligadura pré-amarrada foi colocada para realizar uma biópsia do lobo pulmonar caudal. Não foi realizada insuflação da cavidade torácica. O tempo total de cirurgia foi de 41,4 ± 14,5 min. Os procedimentos foram realizados sem complicações que impedissem o escorregamento ou aperto do nó ou que o soltassem após a biópsia pulmonar; não houve nenhuma intercorrência grave durante o procedimento cirúrgico. As amostras coletadas tinham tamanho médio 1x0,64x0,45 cm e foram consideradas satisfatórias de acordo com a avaliação histopatológica. As radiografias de tórax feitas antes e depois das cirurgias foram comparadas e não mostraram pneumotórax ou hemotórax. A necropsia confirmou que não ocorreu falha do nó no local da biópsia. Conclui-se que uso da nova ligadura com alça pré-amarrada é uma técnica segura e eficaz, evitando problemas com o tamanho limitado da cavidade torácica em pacientes pequenos. RESUMO invasiva corporalmente préamarrada pré amarrada 5kg kg dorsal direita caudal 414 41 4 41, 145 14 5 14, min cirúrgico 1x064x045 xx 1x0 64x0 45 x 1x0,64x0,4 histopatológica hemotórax Concluise Conclui se eficaz pequenos 1 1x064x04 1x 64x 1x0,64x0, 1x064x0 1x0,64x0 1x064x 1x0,64x
ABSTRACT: Thoracoscopy is replacing open lung biopsies because it is less invasive, usually the technique is done using three portals and intracorporeal suture technique. This study described the feasibility and efficacy of a novel pre tied loop ligature and to propose a thoracoscopic access strategy with two portals to perform lung biopsy in patients under 5 kg. Ten rabbits were positioned in dorsal recumbency. Total thoracoscopic lung biopsy was performed using a combined transdiaphragmatic approach and a right intercostal approach. A pre tied loop ligature was placed to perform a caudal lung lobe biopsy. Insufflation of the thoracic cavity was not performed. The total surgery time was 41.4 ± 14.5 min. The procedure was carried out free of complications that prevented slippage or tightening the knot or that made it come loose after the lung biopsy; there was no serious complication during the surgical procedure. The samples obtained averaged 1x0.64x0.45 cm (Length, Width, Depth) and were considered satisfactory according to the histopathologic evaluation. Thorax radiographs taken before and after the surgeries were compared and showed no pneumothorax or hemothorax. Necropsy confirmed no knot failure occurred at the biopsy site. The use of the novel pre tied loop ligature is a safe and effective technique, avoiding problems with the limited size of the thoracic cavity in small patients. ABSTRACT invasive kg recumbency 414 41 4 41. 145 14 14. min 1x064x045 xx 1x0 64x0 45 x 1x0.64x0.4 Length, Length (Length Width Depth evaluation hemothorax site 1 1x064x04 1x 64x 1x0.64x0. 1x064x0 1x0.64x0 1x064x 1x0.64x
15.
O acesso à justiça dos acionistas minoritários do mercado de capitais brasileiro: uma análise à luz dos custos de transação ex post
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Revista Eurolatinoamericana de Derecho Administrativo
- Métricas do periódico
Resumo A consolidação da arbitragem societária impactou na interpretação da garantia do acesso à justiça, sobretudo aos acionistas minoritários. O objetivo do presente artigo consiste em analisar se, a partir da Teoria dos Custos de Transação de Oliver E. Williamson, a adoção compulsória da arbitragem representa ganho para o sistema de enforcement no mercado de capitais brasileiro. Para o desenvolvimento da pesquisa utilizou-se o método científico dedutivo-descritivo e a técnica de pesquisa empírica e bibliográfica. Foi observado que a vinculação de todos os acionistas de determinada companhia à cláusula arbitral está associada a pelo menos dois custos de transação ex post: o custo de má adaptação da arbitragem no mercado de capitais, pois somente o acionista que dispõe de recursos privados substanciais terá a possibilidade de efetivar os seus direitos; e o custo de configuração e funcionamento consistente no total sigilo do procedimento arbitral, o que prejudica a avaliação da efetividade do sistema de proteção de investidores. Na sequência, analisou-se de que forma a estrutura organizacional composta pelos acionistas minoritários poderia modificar as instituições legais analisadas. Por fim, foi possível concluir que o diploma legal atual está ultrapassado e que o sistema de enforcement no mercado de capitais brasileiro não é igualmente eficiente a todos os players.
Abstract The consolidation of corporate arbitration had an impact on the interpretation of the guarantee of access to justice, especially for minority shareholders. The purpose of this article is to analyze whether, based on Oliver E. Williamson's Theory of Transaction Costs, the compulsory adoption of arbitration represents a gain for the enforcement system in the Brazilian capital market. For the development of this research, the deductive-descriptive scientific method and the empirical and bibliographical research technique were used. It was observed that the binding of all shareholders of a given company to the arbitration clause is associated with at least two ex post transaction costs: the cost of poor adaptation of arbitration in the capital market, as only the shareholder who has substantial private resources will be able to exercise his rights; and a configuration and operating cost consistent with the total secrecy of the arbitration procedure, which undermines the assessment of the effectiveness of the investor protection system. Next, an analysis was made of how the organizational structure composed of minority shareholders could modify the analyzed legal institutions. Finally, it was possible to conclude that the current legal diploma is outdated and that the enforcement system in the Brazilian capital market is not equally efficient for all players.
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