ABSTRACT Objective: This study evaluated the accuracy and precision of digital models acquisition using a home-built, low-cost scanning system based on the structured light method. Methods: a plaster model (PM) was scanned using the experimental device (SL) and a dental desktop scanner (DS). The teeth dimensions of PM and SL models were measured in triplicate, with a caliper and digitally, respectively. The agreement of the measurements of each model was evaluated using the intraclass correlation coefficient, and the validity between the different measurement techniques was assessed using the Bland-Altman analysis. The accuracy and precision of the models were qualitatively investigated using the mesh superposition of the SL and DS models. Results: A high intraclass correlation coefficient was observed in all models (PM=0.964; SL1=0.998; SL2=0.995; SL3=0.998), and there was no statistical difference between the measurements of the SL models (p>0.05). PM and SL model measurements were found to be in good agreement, with only 3.57% of the observed differences between the same measurement being located outside 95% limits of agreement according to Bland and Altman (0.43 and -0.40 mm). In the superimpositions of SL-SL and SL-DS models, areas of discrepancy greater than 0.5 mm were observed mainly in interproximal, occlusal, and cervical sites. Conclusion: These results indicate that the home-built SL scanning system did not possess sufficient accuracy and precision for many clinical applications. However, the consistency in preserving the dental proportions suggests that the equipment can be used for planning, storage, and simple clinical purposes. Objective homebuilt, homebuilt home built, built lowcost low cost method Methods (PM (SL DS. . (DS) triplicate digitally respectively BlandAltman analysis Results PM=0.964 PM0964 0 964 (PM=0.964 SL1=0.998 SL10998 SL1 998 SL2=0.995 SL20995 SL2 995 SL3=0.998, SL30998 SL3=0.998 , SL3 SL3=0.998) p>0.05. p005 p p>0.05 05 (p>0.05) 357 3 57 3.57 95 0.43 043 43 (0.4 0.40 040 40 -0.4 mm. mm) SLSL SLDS 5 0. interproximal occlusal sites Conclusion applications However planning storage purposes (DS PM=0.96 PM096 96 (PM=0.96 SL1=0.99 SL1099 99 SL2=0.99 SL2099 SL3099 SL3=0.99 p00 p>0.0 (p>0.05 35 3.5 9 0.4 04 4 (0. -0. PM=0.9 PM09 (PM=0.9 SL1=0.9 SL109 SL2=0.9 SL209 SL309 SL3=0.9 p0 p>0. (p>0.0 3. (0 -0 PM=0. PM0 (PM=0. SL1=0. SL10 SL2=0. SL20 SL30 SL3=0. p>0 (p>0. ( - PM=0 (PM=0 SL1=0 SL2=0 SL3=0 p> (p>0 PM= (PM= SL1= SL2= SL3= (p> (p

RESUMO Objetivo: Este estudo avaliou a acurácia e a precisão da aquisição de modelos digitais utilizando um sistema de digitalização caseiro e de baixo custo baseado no método de luz estruturada. Material e Métodos: Para isso, um modelo de gesso (MG) foi digitalizado utilizando o dispositivo experimental (LE) e um scanner dental de mesa (SD). As dimensões dos dentes dos modelos MG e LE foram medidas em triplicata com um paquímetro e digitalmente, respectivamente. A concordância das medidas de cada modelo foi avaliada usando o coeficiente de correlação intraclasse, e a validade entre as diferentes técnicas de medição foi avaliada usando a análise de Bland-Altman. A acurácia e a precisão dos modelos foram investigadas qualitativamente usando a sobreposição de malhas dos modelos LE e SD. Resultados: Um alto coeficiente de correlação intraclasse foi observado em todos os modelos (MG=0,964; LE1=0,998; LE2=0,995; LE3=0,998) e não houve diferença estatística entre as medições dos modelos LE (p>0,05). As medições dos modelos MG e LE mostraram boa concordância, com apenas 3,57% das diferenças observadas entre as mesmas medições localizadas fora dos limites de concordância de 95% de acordo com a análise de Bland-Altman (0,43 e -0,40 mm). Nas sobreposições dos modelos LE-LE e LE-SD, foram observadas áreas de discrepância maiores que 0,5 mm principalmente nos sítios interproximais, oclusais e cervicais. Conclusões: Esses resultados indicam que o sistema de digitalização por luz estruturada caseiro não possui precisão e acurácia suficientes para muitas aplicações clínicas. No entanto, a consistência na preservação das proporções dentárias sugere que o equipamento pode ser usado para planejamento, armazenamento e propósitos clínicos simples. Objetivo Métodos isso (MG (LE SD . (SD) digitalmente respectivamente BlandAltman. BlandAltman Bland Altman. Altman Resultados MG=0,964 MG0964 0 964 (MG=0,964 LE1=0,998 LE10998 LE1 998 LE2=0,995 LE20995 LE2 995 LE3=0,998 LE30998 LE3 p>0,05. p005 p p>0,05 05 (p>0,05) 357 3 57 3,57 95 0,43 043 43 (0,4 0,40 040 40 -0,4 mm. mm) LELE LESD, LESD SD, LE-SD 5 0, interproximais cervicais Conclusões clínicas entanto planejamento simples (SD MG=0,96 MG096 96 (MG=0,96 LE1=0,99 LE1099 99 LE2=0,99 LE2099 LE3=0,99 LE3099 p00 p>0,0 (p>0,05 35 3,5 9 0,4 04 4 (0, -0, MG=0,9 MG09 (MG=0,9 LE1=0,9 LE109 LE2=0,9 LE209 LE3=0,9 LE309 p0 p>0, (p>0,0 3, (0 -0 MG=0, MG0 (MG=0, LE1=0, LE10 LE2=0, LE20 LE3=0, LE30 p>0 (p>0, ( - MG=0 (MG=0 LE1=0 LE2=0 LE3=0 p> (p>0 MG= (MG= LE1= LE2= LE3= (p> (p

Abstract The alkali-silica reaction (ASR) is one of the problems that can compromise concrete durability, as the chemical reactions between the reactive aggregate and concrete pore solution, specifically sodium (Na+), potassium (K+), calcium (Ca2+) and hydroxyl (OH-) in the presence of moisture, trigger expansion and cracking of concrete elements. The use of pozzolanic materials, such as finely ground glass powder (particles smaller than 75μm), to partially replace cement has been widely studied and has demonstrated beneficial results. However, because the behavior of pozzolans towards ASR is not completely understood yet, this work evaluates the effect of incorporating ground glass powder into cementitious composites against ASR. To this end, 8% silica fume was used as a control admixture, and four levels of glass powder (10, 20, 30, and 50%) were incorporated into the cementitious mixture to partially replace cement. Expansion tests were carried out in accordance with NBR15577-4 (ABNT, 2018) on mortar bars using the accelerated test method to assess the mitigation of expansions. The results show that the expansions caused by ASR decreased with the increasing content of glass powder in the cement mixtures. Furthermore, only the 50% level reduced the expansions to a safe value according to the Brazilian standard. alkalisilica alkali (ASR durability solution Na+, Na Na+ , (Na+) K+, K K+ (K+) Ca2+ Ca2 Ca (Ca2+ OH (OH- moisture elements materials particles 75μm, 75μm μm 75μm) However yet end 8 admixture 10, 10 (10 20 30 50 NBR155774 NBR NBR15577 4 NBR15577- ABNT, ABNT (ABNT 2018 mixtures Furthermore standard (Na+ (K+ (Ca2 (OH 1 (1 2 3 5 NBR1557 201 (Na (K (Ca ( NBR155 NBR15 NBR1

Resumo A reação álcali-sílica (RAS) é um dos problemas que pode comprometer a durabilidade do concreto, uma vez que as reações químicas entre o agregado reativo e a solução porosa do concreto, em particular, sódio (Na+), potássio (K+), cálcio (Ca2+) e hidroxila (OH-) na presença de umidade, desencadeiam a expansão e fissuração dos elementos de concreto. O uso de materiais pozolânicos, como o pó de vidro finamente moído (com partículas abaixo de 75μm), para substituir parcialmente o cimento, tem sido amplamente estudado e demonstrou resultados benéficos. No entanto, devido ao fato de que o comportamento das pozolanas em relação à RAS ainda não é completamente compreendido, este trabalho avalia o efeito da incorporação de pó de vidro moído em compósitos cimentícios frente a RAS. Para isso, 8% de sílica ativa como controle, e quatro teores de pó de vidro (10, 20, 30 e 50%) foram incorporados à mistura cimentícia em substituição parcial ao cimento. Testes de expansão foram realizados de acordo com a NBR15577-4 (ABNT, 2018) em barras de argamassa usando o método de teste acelerado para avaliar a mitigação das expansões. Os resultados mostram que as expansões causadas pela RAS diminuíram com o aumento do teor de pó de vidro das misturas de cimento. Além disso, apenas o nível de 50% reduziu as expansões a um valor seguro de acordo com a norma brasileira. álcalisílica álcali (RAS concreto particular Na+, Na Na+ , (Na+) K+, K K+ (K+) Ca2+ Ca2 Ca (Ca2+ OH (OH- umidade pozolânicos 75μm, 75μm μm 75μm) cimento benéficos entanto compreendido isso 8 controle 10, 10 (10 20 3 50 NBR155774 NBR NBR15577 4 NBR15577- ABNT, ABNT (ABNT 2018 disso brasileira (Na+ (K+ (Ca2 (OH 1 (1 2 5 NBR1557 201 (Na (K (Ca ( NBR155 NBR15 NBR1

SUMMARY OBJECTIVE: This study aimed to evaluate the quality of sleep in individuals with systemic sclerosis and its correlation with the quality of life and disability. METHODS: This is a cross-sectional study, carried out in a tertiary service of a university hospital. Inclusion criteria were diagnosis of systemic sclerosis according to the criteria of the American College of Rheumatology/European League Against Rheumatism 2013 or the preliminary criteria of the American College of Rheumatology 1980, age ≥ 18 years; regularly monitored at the outpatient clinic of rheumatology. Clinical and demographic data of the patients were obtained through a structured interview and evaluation of the medical records. Sleep quality was assessed using the Pittsburgh Sleep Quality Index questionnaire, daytime sleepiness using the Epworth Sleepiness Scale, quality of life using 12-item short-form health survey, and disability using the scleroderma health assessment questionnaire. RESULTS: A total of 50 patients with systemic sclerosis were included, with 92% female, mean age 48.9 years, mean disease duration 8.9 years, and 60% limited cutaneous form. Most systemic sclerosis patients (84%) have poor sleep quality and 20% have excessive daytime sleepiness. There was a significant negative correlation between Pittsburgh Sleep Quality Index and the physical and mental components of the 12-item short-form health survey (r=-0.42, p=0.003 and r=-0.43, p=0.002, respectively) and a positive correlation with the scleroderma health assessment questionnaire (r=0.52, p=<0.001). CONCLUSION: This study showed that poor sleep quality is a very common finding among systemic sclerosis patients, and it negatively affects both the quality of life and the degree of disability. OBJECTIVE METHODS crosssectional cross sectional hospital RheumatologyEuropean European 201 1980 1 years rheumatology records Scale 12item item 12 shortform short form RESULTS 5 included 92 female 489 48 9 48. 89 8 8. 60 84% 84 (84% 20 r=0.42, r042 r r= 0.42, 0 42 (r=-0.42 p0003 p 003 p=0.00 r=0.43, r043 0.43, 43 r=-0.43 p0002 002 p=0.002 respectively r=0.52, r052 52 (r=0.52 p=<0.001. p0001 p=<0.001 . 001 p=<0.001) CONCLUSION 198 4 6 (84 2 r=0.42 r04 042 0.42 (r=-0.4 p000 00 p=0.0 r=0.43 043 0.43 r=-0.4 r=0.52 r05 (r=0.5 p=<0.00 19 (8 r=0.4 r0 04 0.4 (r=-0. p00 p=0. r=-0. r=0.5 (r=0. p=<0.0 ( r=0. 0. (r=-0 p0 p=0 r=-0 (r=0 p=<0. r=0 (r=- p= r=- (r= p=<0 (r p=<

Abstract In a still worrying epidemic scenario, the prevention of Vertical Transmission (VT) of HIV poses complex problems, due to the individual, social, and moral vulnerabilities of women living with the virus, in addition to the weaknesses of the health network. Based on an emblematic case, this study sought to understand the bioethical challenges of HIV VT prevention in the scope of the Porto Alegre/RS Committee. The analytical categories developed reflect on how the production of care is articulated, on the one hand, with relational discourses and practices based on gender and intersected by race and social class and, on the other, with programmatic vulnerabilities of health policies. A process of extreme stigmatization was revealed, in which the few offers for cisgender women were aimed toward reproductive regulation and perpetuated dynamics of structural violence. We discuss ways of building care that incorporates a decolonial perspective and seeks to produce equity and social justice by recognizing women’s trajectories. scenario (VT problems individual virus network case AlegreRS Alegre RS Committee articulated hand other policies revealed violence womens s trajectories

Resumo Num cenário epidêmico ainda preocupante, a prevenção da Transmissão Vertical (TV) do HIV impõe problemas complexos, devido as vulnerabilidades individual, social e moral das mulheres vivendo com o vírus, somadas às fragilidades da rede de saúde. A partir de um caso emblemático, este estudo buscou compreender os desafios bioéticos do cuidado para a prevenção da TV do HIV no âmbito do Comitê de Porto Alegre/RS. Os eixos analíticos desenvolvidos refletem sobre como a produção do cuidado se articula, por um lado, com discursos e práticas relacionais pautadas no gênero e interseccionadas por raça e classe social e, por outro, com vulnerabilidades programáticas das políticas de saúde. Vislumbrou-se um processo de extrema estigmatização, em que as poucas ofertas para as mulheres cisgênero se dirigiam à regulação reprodutiva e perpetuavam dinâmicas de violência estrutural. Discute-se caminhos para a construção de um cuidado que incorpore a perspectiva decolonial e busque produzir equidade e justiça social ao reconhecer as trajetórias das mulheres. preocupante (TV complexos individual vírus saúde emblemático AlegreRS Alegre RS Alegre/RS articula lado outro Vislumbrouse Vislumbrou estigmatização estrutural Discutese Discute

Hydrogel films based on gelatin, glutaraldehyde and glycerol are widely reported in many studies with applications focused on food packaging, microencapsulation and release of active drugs. Thus, this study used this composition to produce hydrogel films and brought as a novelty the incorporation of tannic acid (TA) as anti-aging active, due to its great antioxidant capacity. The presence of TA in the hydrogel films was verified by the C–O stretch absorption band at 1020 cm-1, as well as by its thermal degradation between 200 and 300 ºC. Furthermore, the presence of this active compound, which influenced the physical, morphological and mechanical properties of the film, was also confirmed by qualitative release tests. Additionally, the mechanical properties of the HT2 hydrogel film showed acceptable values of elongation at break (28.9 ± 3.1%) and Young modulus (6.4 ± 1.1 MPa), suggesting that this film has the potential to be applied in skin care routines. gelatin packaging drugs Thus (TA antiaging anti aging capacity CO C O 102 cm1, cm1 cm 1, 1 cm-1 20 30 ºC Furthermore compound physical tests Additionally HT 28.9 289 28 9 (28. 3.1% 31 3 6.4 64 6 4 (6. 11 1. MPa, MPa , MPa) routines 10 cm- 2 28. (28 3.1 6. (6 (2 3. (

ABSTRACT Objective: To identify the clinical presentation of molar incisor hypomineralization (MIH) and hypomineralization of second primary molars (HSPM), including the distribution patterns of presence and severity of lesions, and to investigate the association of risk factors during the pre-and postnatal period with the presence of lesions. Material and Methods: This cross-sectional study was conducted with 160 individuals (72 with MIH/HSPM and 88 without lesions). The symmetry analysis regarding the presence and severity of MIH/HSPM was evaluated in pairs of homologous and opposite teeth. Sociodemographic and medical information was obtained using a detailed questionnaire. Data were analyzed by means of chi-square tests, Student’s t-test, and logistic regression (p<0.05). Results: Symmetry of presence and severity of hypomineralization lesions were present in homologous permanent teeth in 53.8% and 70.5% of cases, respectively, with statistically significant results only for the symmetrical pattern of severity of MIH lesions in the maxillary first molars (p=0.016) and mandibular first molars (p=0.02). Otherwise, a non-symmetric presence was statistically significant in homologous second primary molars (p=0.002) and opposite primary and permanent teeth (p≤0.001). An association between MIH/HSPM and systemic diseases during pregnancy and children medication was found (p<0.05); however, no evidence was found between these and MIH/HSPM severity. Conclusion: The symmetric pattern of severity of MIH lesions was statistically significant in permanent homologous teeth. Risk factors during pre and postnatal periods may be related to MIH/HSPM; however, these do not seem to interact with severity. Objective (MIH HSPM, HSPM , (HSPM) preand Methods crosssectional cross sectional 16 72 (7 MIHHSPM 8 . lesions) questionnaire chisquare chi square tests Students Student s ttest, ttest t test, test t-test p<0.05. p005 p p<0.05 0 05 (p<0.05) Results 538 53 53.8 705 70 5 70.5 cases respectively p=0.016 p0016 016 (p=0.016 p=0.02. p002 p=0.02 02 (p=0.02) Otherwise nonsymmetric non p=0.002 p0002 002 (p=0.002 p≤0.001. p0001 p≤0.001 001 (p≤0.001) however Conclusion (HSPM 1 7 ( p00 p<0.0 (p<0.05 53. 70. p=0.01 p001 01 (p=0.01 p=0.0 (p=0.02 p=0.00 p000 00 (p=0.00 p≤0.00 (p≤0.001 p0 p<0. (p<0.0 (p=0.0 p=0. p≤0.0 (p≤0.00 p<0 (p<0. (p=0. p=0 p≤0. (p≤0.0 p< (p<0 (p=0 p= p≤0 (p≤0. (p< (p= p≤ (p≤0 (p (p≤

ABSTRACT The varied clinical presentations of SARS-CoV-2 infection have raised concerns about long-term consequences, especially “long-COVID” or “post-COVID-19 syndrome.” In this context, the cardiorespiratory optimal point (COP) within the Cardiopulmonary Exercise Test (CPET) emerges as a crucial metric for evaluating functional capacities and detecting cardiovascular and pulmonary anomalies post-COVID-19. This study aimed to assess COP values among post-COVID-19 patients and categorized them based on the initial severity of their disease. In this cross-sectional study conducted in the Northeast Brazil, 80 patients (26 females and 54 males) previously infected with SARS-CoV-2 underwent CPET. We clinically stratified patients into mild, moderate, or severe COVID-19 categories and assessed COP values and other cardiorespiratory metrics. We found differences in the predicted COP between patients with mild and severe COVID-19 (p=0.042). Additionally, patients with moderate and severe COVID-19 record had an average COP value exceeding 22. Other parameters, including respiratory exchange ratio, heart rate, and oxygen uptake efficiency slope, did not differ across the groups. Patients with a history of severe COVID-19 showed altered COP values, suggesting potential discrepancies in cardiovascular and respiratory system integration. The outcomes emphasize the importance of continuous monitoring and assessment of the cardiorespiratory domain for post-COVID-19 patients. Further research is needed to understand the relationship between elevated COP in post-severe COVID-19 and its long-term prognostic implications. SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- longterm long term consequences longCOVID COVID “long-COVID postCOVID19 postCOVID post 19 “post-COVID-1 syndrome. syndrome context (COP CPET (CPET postCOVID19. 19. post-COVID-1 disease crosssectional cross sectional Brazil 8 26 (2 5 males COVID19 COVID-1 metrics p=0.042. p0042 p p=0.042 . 0 042 (p=0.042) Additionally 22 parameters ratio rate slope groups integration postsevere implications SARS-CoV postCOVID1 1 “post-COVID- post-COVID- ( COVID1 COVID- p004 p=0.04 04 (p=0.042 “post-COVID post-COVID p00 p=0.0 (p=0.04 p0 p=0. (p=0.0 p=0 (p=0. p= (p=0 (p= (p

Abstract Objective To investigate the acceptability and adequacy of a multicomponent exercise program via videoconferencing for the oldest-old in Porto Alegre, a city in southern Brazil. Method This is a quasi-experimental study. Fourteen participants were enrolled in the multicomponent exercise program Vivifrail® for 12 weeks, 5 days a week, with weekly video calls for assessment of acceptability and adequacy. The acceptability and adequacy questionnaire was based on 6 barriers that older adults face when engaging in physical exercise. Responses were measured using a 5-point Likert scale ranging from 0 to 4 points, with a maximum score of 24 points (maximum acceptability). Results Fourteen participants (89.07±6.30 years) concluded the protocol, with an acceptability rate of 70%. Internal consistency was moderate, with a Cronbach’s coefficient alpha of 0.7. Participants showed an overall increase in acceptability and adequacy (from 17.8±3.51 points in the first week to 22.0±2.94 in the 12th week). Four participants (28.6%) required some modification to the exercise protocol. Conclusion The Vivifrail® protocol, together with weekly follow-up via videoconferencing, was well accepted and adequate. It could be an important tool for promoting quality of life, especially in the oldest-old with difficulty leaving home. The acceptability questionnaire was able to detect exercise barriers and suggest possible modifications to the training program and could be presented as a suggestion for the evaluation of intervention protocols in the oldest-old population. Therefore, the Vivifrail® protocol, with weekly follow-up via videoconferencing, could be a new field of intervention for health professionals. oldestold oldest old Alegre Brazil quasiexperimental quasi experimental study Vivifrail 1 weeks 5point point 2 acceptability. . acceptability) 89.07±6.30 8907630 89 07 30 (89.07±6.3 years protocol 70 70% moderate Cronbachs Cronbach s 7 0.7 178351 17 8 3 51 17.8±3.5 220294 22 94 22.0±2.9 th week. week) 28.6% 286 28 (28.6% followup follow up adequate life home population Therefore professionals 89.07±6.3 890763 (89.07±6. 0. 17835 17.8±3. 22029 9 22.0±2. 28.6 (28.6 89.07±6. 89076 (89.07±6 1783 17.8±3 2202 22.0±2 28. (28. 89.07±6 8907 (89.07± 178 17.8± 220 22.0± (28 89.07± 890 (89.07 17.8 22.0 (2 89.07 (89.0 17. 22. ( 89.0 (89. 89. (89 (8

Resumo Objetivo Investigar a aceitação e adequação de um programa de exercícios multicomponentes por videoconferência para longevos em Porto Alegre (RS), Brasil. Método Estudo Quase experimental. Os participantes realizaram o protocolo de exercícios multicomponentes ViviFrail® durante 12 semanas, com a aceitação e adequação avaliadas semanalmente por videoconferência. O questionário de aceitação e adequação foi baseado em uma escala Likert (de 0 a 4) de seis barreiras que os participantes enfrentam ao fazer exercício físico, com pontuação máxima de 24 pontos (aceitação máxima). Resultados A aceitação foi de 70%, com 14 participantes concluindo o protocolo (89,07±6,30 anos). A consistência interna, (alfa de Cronbach) para o questionário, foi de 70%, considerada moderada. Os participantes mostraram um aumento geral na aceitação dos 17,8±3,51 pontos iniciais, para 22,0±2,94 pontos no final. Quatro (28.6%) necessitaram de adequação no protocolo de exercício. Conclusão O programa de exercícios multicomponente ViviFrail®, com acompanhamento através de videoconferência, foi bem aceito e adequado, podendo ser uma importante ferramenta para a promoção da qualidade de vida, principalmente em longevos com dificuldade de sair de casa, tanto por problemas de mobilidade, quanto por ambientes sociais desfavoráveis (violência urbana e situações sanitárias). O questionário de aceitação e adequação, que necessitou ser criado, foi capaz de detectar barreiras do RS, RS , (RS) Brasil experimental ViviFrail 1 semanas 4 físico 2 máxima. . máxima) 70 70% 89,07±6,30 8907630 89 07 6 30 (89,07±6,3 anos. anos anos) interna alfa Cronbach moderada 178351 17 8 3 51 17,8±3,5 iniciais 220294 22 94 22,0±2,9 final 28.6% 286 28 (28.6% adequado vida casa mobilidade violência sanitárias. sanitárias sanitárias) criado (RS 7 89,07±6,3 890763 (89,07±6, 17835 5 17,8±3, 22029 9 22,0±2, 28.6 (28.6 89,07±6, 89076 (89,07±6 1783 17,8±3 2202 22,0±2 28. (28. 89,07±6 8907 (89,07± 178 17,8± 220 22,0± (28 89,07± 890 (89,07 17,8 22,0 (2 89,07 (89,0 17, 22, ( 89,0 (89, 89, (89 (8

RESUMEN Objetivos: analizar las tecnologías utilizadas por el equipo de enfermería en el tratamiento de lesiones cutáneas causadas por quemaduras en pacientes en cuidados intensivos. Métodos: se trata de una revisión de alcance realizada en las bases de datos LILACS, Medline, PubMed y CINAHL sin restricciones temporales ni de idioma. Resultados: las tecnologías destacadas incluyeron el uso de coberturas especializadas, agentes biológicos como probióticos y cianobacterias, además de terapias de presión negativa y enzimas como la papaína y la colagenasa. Algunas tecnologías, como la plata nanocristalina, mostraron eficacia en el control de infecciones. Consideraciones Finales: el estudio identificó las tecnologías esenciales en la atención de quemaduras, enfatizando la necesidad de investigaciones adicionales sobre tecnologías “leves”. Los hallazgos respaldan la promoción de una atención de enfermería basada en evidencia para pacientes quemados en cuidados intensivos y mejoran el conocimiento sobre tratamientos efectivos. Objetivos Métodos LILACS Medline idioma Resultados especializadas cianobacterias colagenasa nanocristalina infecciones Finales leves. leves . “leves” efectivos “leves

ABSTRACT Objectives: to analyze the technologies used by the nursing team in the treatment of skin lesions caused by burns in patients under intensive care. Methods: this is a scope review conducted on the LILACS, Medline, PubMed, and CINAHL databases without temporal or language restrictions. Results: the highlighted technologies included the use of specialized dressings, biological agents such as probiotics and cyanobacteria, as well as negative pressure therapies and enzymes such as papain and collagenase. Some technologies, such as nanocrystalline silver, demonstrated efficacy in infection control. Final Considerations: the study identified essential technologies in burn care, emphasizing the need for further research on “soft” technologies. The findings support the promotion of evidence-based nursing care for burn patients in intensive care and enhance knowledge about effective treatments. Objectives Methods LILACS Medline PubMed restrictions Results dressings cyanobacteria collagenase silver control Considerations soft “soft evidencebased evidence based treatments

RESUMO Objetivos: analisar as tecnologias utilizadas pela equipe de enfermagem no tratamento de lesões cutâneas causadas por queimaduras em pacientes sob cuidados intensivos. Métodos: trata-se de uma revisão de escopo realizada nas bases LILACS, Medline, PubMed e CINAHL sem restrição temporal ou de idiomas. Resultados: as tecnologias destacadas abrangeram o uso de coberturas especializadas, agentes biológicos como probióticos e cianobactérias, além de terapias de pressão negativa e enzimas como a papaína e colagenase. Algumas tecnologias, como a prata nanocristalina, mostraram eficácia no controle de infecções. Considerações Finais: o estudo identificou as tecnologias essenciais na assistência às queimaduras, enfatizando a necessidade de pesquisas adicionais sobre tecnologias “leves”. As descobertas sustentam a promoção de uma assistência de enfermagem baseada em evidências para pacientes queimados sob cuidados intensivos e aprimoram o conhecimento sobre tratamentos eficazes. Objetivos Métodos tratase trata se LILACS Medline idiomas Resultados especializadas cianobactérias colagenase nanocristalina infecções Finais leves. leves . “leves” eficazes “leves

ABSTRACT Objective: To investigate the effect of bronchodilator on the respiratory mechanics and pulmonary function of children and adolescents with cystic fibrosis. Methods: Cross-sectional study on clinically stable children and adolescents with cystic fibrosis aged from six to 15 years. Participants underwent impulse oscillometry and spirometry evaluations before and 15 minutes after bronchodilator inhalation. The Kolmogorov-Smirnov test was applied to verify the sample distribution, and the Student's t-test and Wilcoxon test were used to compare the data before and after bronchodilator inhalation. Results: The study included 54 individuals with a mean age of 9.7±2.8 years. The analysis showed a statistically significant improvement in impulse oscillometry and spirometry parameters after bronchodilator inhalation. However, according to the American Thoracic Society (ATS) and European Respiratory Society (ERS) recommendations (2020 and 2021), this improvement was not sufficient to classify it as a bronchodilator response. Conclusions: The use of bronchodilator medication improved respiratory mechanics and pulmonary function parameters of children and adolescents with cystic fibrosis; however, most patients did not show bronchodilator response according to ATS/ERS recommendations. Objective Methods Crosssectional Cross sectional 1 years inhalation KolmogorovSmirnov Kolmogorov Smirnov distribution Students Student s ttest t Results 5 9728 9 7 2 8 9.7±2. However ATS (ATS ERS (ERS 2020 (202 2021, 2021 , 2021) Conclusions however ATSERS 972 9.7±2 202 (20 97 9.7± 20 (2 9.7 ( 9.

RESUMO Objetivo: Investigar o efeito do broncodilatador na mecânica respiratória e função pulmonar de crianças e adolescentes com fibrose cística. Métodos: Estudo transversal em crianças e adolescentes com fibrose cística clinicamente estáveis, com idade entre seis e 15 anos. Os participantes realizaram avaliações por meio do sistema de oscilometria de impulso e espirometria antes e 15 minutos depois da inalação de broncodilatador. Foi aplicado o teste Kolmogorov-Smirnov para verificar a distribuição da amostra. Para comparar os dados antes e depois do broncodilatador foram utilizados os testes t de Student e Wilcoxon. Resultados: Participaram do estudo 54 indivíduos com média de idade de 9,7±2,8 anos. Houve melhora estatisticamente significativa nos parâmetros do oscilometria de impulso e espirometria após a inalação com broncodilatador. No entanto, de acordo com recomendações da American Thoracic Society (ATS) e European Respiratory Society (ERS) (2020 and 2021), essa melhora não foi suficiente para classificar como reposta broncodilatadora. Conclusões: O uso de medicamento broncodilatador melhorou a mecânica respiratória e função pulmonar de crianças e adolescentes com fibrose cística, no entanto a maioria da amostra não apresentou resposta ao broncodilatador de acordo com as recomendações da ATS/ERS. Objetivo Métodos estáveis 1 anos KolmogorovSmirnov Kolmogorov Smirnov Wilcoxon Resultados 5 9728 9 7 2 8 9,7±2, ATS (ATS ERS (ERS 2020 (202 2021, 2021 , 2021) broncodilatadora Conclusões ATSERS ATS/ERS 972 9,7±2 202 (20 97 9,7± 20 (2 9,7 ( 9,

Abstract Objective: To identify the prevalence, severity, hypersensitivity, and distribution of Non-carious cervical lesions (NCCL) among university students in Brazil. Material and Methods: 179 participants answered an anamnesis with twenty questions about the presence or absence of habits associated with NCCL. The participants' teeth were evaluated to identify the presence or absence of the lesion, its classification, involved surfaces, severity, hypersensitivity, and tooth wear index. A hypersensitivity test was performed with ice water. Data were analyzed using the chi-square test and simple logistic regression (p<0.01). Results: 179 participants answered an anamnesis with twenty questions about the presence or absence of habits associated with NCCL. The participants' teeth were evaluated to identify the presence or absence of the lesion, its classification, involved surfaces, severity, hypersensitivity, and tooth wear index. A hypersensitivity test was performed with ice water. Data were analyzed using the chi-square test and simple logistic regression (p<0.01). Conclusion: The prevalence of NCCL was 15.1% and abfraction was the most frequent lesion. Premolars were the teeth most affected by non-carious cervical lesions. Objective severity Noncarious Non carious (NCCL Brazil Methods 17 lesion classification surfaces index water chisquare chi square p<0.01. p001 p p<0.01 . 0 01 (p<0.01) Results Conclusion 151 15 1 15.1 noncarious non p00 p<0.0 (p<0.01 15. p0 p<0. (p<0.0 p<0 (p<0. p< (p<0 (p< (p

ABSTRACT Post-acute COVID-19 syndrome, or long COVID, presents with persistent symptoms, including cough, dyspnea, and fatigue, extending beyond one month after SARS-CoV-2 infection. Cardiac complications such as chest pain and arrhythmias have raised concerns, with chronotropic incompetence (CI), an inadequate heart rate increase during exercise, emerging as a significant condition contributing to diminished exercise tolerance and quality of life. This study estimated the prevalence of CI and explored its association with aerobic capacity and physical activity levels in long COVID patients. A cross-sectional study was conducted at a private hospital in Sergipe, Brazil, involving 93 patients over 18 years old with persistent post-COVID-19 symptoms after confirmed SARS-CoV-2 infections. Exclusion criteria included beta-blocker use, inadequate respiratory exchange ratio, and inability to complete cardiopulmonary exercise testing (CPET). Clinical histories, CPET results, and chronotropic index calculation were used to identify CI, with logistic regression analyzing associated factors. Of the participants (mean age 45 years; average duration since COVID-19 diagnosis 120 days), 20.4% were diagnosed with CI. Logistic regression identified a strong association between CI and sedentary behavior (OR 11.80; 95% CI 2.54 to 54.78; p=0.001). Patients with CI showed lower predicted peak heart rates and maximal oxygen uptake. The prevalence of CI among long COVID patients in this study was approximately 20%, associated with decreased aerobic capacity and increased sedentary behavior. These findings highlight the need for timely diagnosis and therapeutic interventions, including cardiopulmonary rehabilitation, to enhance the quality of life in post-COVID patients with CI. The study’s cross-sectional design and its specific context have limited causality inference and generalizability, underscoring the importance of further research in diverse settings. Postacute Post acute COVID19 19 COVID-1 syndrome cough dyspnea fatigue SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- infection concerns , (CI) crosssectional cross sectional Sergipe Brazil 9 1 postCOVID19 postCOVID post post-COVID-1 infections betablocker beta blocker use ratio CPET. . (CPET) histories results factors mean 4 12 days, days days) 204 20 20.4 OR 11.80 1180 11 80 95 254 54 2.5 54.78 5478 78 p=0.001. p0001 p p=0.001 0 001 p=0.001) uptake 20% interventions rehabilitation studys s generalizability settings COVID1 COVID- SARS-CoV (CI postCOVID1 post-COVID- (CPET 20. 11.8 118 8 25 5 2. 54.7 547 7 p000 p=0.00 00 11. 54. p00 p=0.0 p0 p=0. p=0 p=

Abstract This study aimed to evaluate in vitro the effect protocols and anticaries agents containing casein amorphous calcium fluoride phosphopeptide-phosphate (CPP-ACPF, MI Paste Plus), sodium trimetaphosphate (TMP) and fluoride (F), in remineralization of caries lesions. Bovine enamel blocks with initial caries lesions were divided into groups (n = 12): 1) Toothpaste without F-TMP-MI Plus (Placebo); 2) Toothpaste 1100 ppm F (1100F), 3) 1100F + MI Paste Plus (1100F-MI Paste Plus), 4) Toothpaste with 1100F + Neutral gel with 4,500 ppm F + 5%TMP (1100F + Gel TMP) and 5) Toothpaste with 1100F + Neutral gel with 9,000 ppm F (1100F + Gel F). For the 4 and 5 groups the gel was applied only once for 1 minute, initially to the study. For the 3 group, after treatment with 1100F, MI Paste Plus was applied 2x/day for 3 minute. After pH cycling, the percentage of surface hardness recovery (%SHR); integrated loss of subsurface hardness (ΔKHN); profile and depth of the subsuperficial lesion (PLM); concentrations of F, calcium (Ca) and phosphorus (P) in enamel was determined. The data were analyzed by ANOVA (1-criterion) and Student-Newman-Keuls test (p < 0.001). Treatment with 1100F alone led to ~ 28% higher remineralization when compared to treatment with 1100F associated with MI Paste Plus (p < 0.001). The 1100F and 1100F + Gel F groups showed similar values for %SHR (p = 0.150). 1100F + Gel TMP treatment also remineralized the enamel surface by ~ 30% and 20% when compared to the 1100F + Gel F and 1100F groups (p < 0.001). The lower lesion depth (ΔKHN) was observed for the 1100F + Gel TMP group (p < 0.001), where it was 54% and 44% lower in comparison to the 1100F and 1100F + Gel F groups (p < 0.001). Polarized light microscopy photomicrographs showed subsurface lesions in all groups, but these lesions were present to a lower extent in the 1100F + Gel TMP group (p < 0.001). Treatment with 1100F + Gel TMP promoted an increase in the concentration of Ca in the enamel by ~ 57% and ~ 26% when compared to the 1100F and 1100F + MI Paste Plus groups (p < 0.001), respectively. There were no significant differences between the 1100F, 1100F + MI Paste Plus and 1100F + Gel F groups (p > 0.001). Similar values of P in the enamel were observed in the 1100F, 1100F + MI Paste Plus and 1100F + Gel F groups (p > 0.001), except for the 1100F + Gel TMP group, which presented a high concentration (p < 0.001). We conclude that the 1100F+TMP gel treatment/protocol led to a significant increased remineralization when compared to the other treatments/protocols and may be a promising strategy for patients with early caries lesions. phosphopeptidephosphate phosphopeptide phosphate CPPACPF, CPPACPF CPP ACPF, ACPF (CPP-ACPF Plus, , Plus) (TMP (F) n 12 12) FTMPMI Placebo (Placebo) 2 110 (1100F) 1100FMI FMI 4500 500 4,50 5TMP 9000 9 000 9,00 F. . F) minute 2xday xday 2x day x cycling SHR (%SHR) ΔKHN PLM (PLM) (Ca (P determined 1criterion criterion (1-criterion StudentNewmanKeuls Student Newman Keuls p 0.001. 0001 0.001 0 001 0.001) 28 0.150. 0150 0.150 150 0.150) 30 20 (ΔKHN 0.001, 54 44 57 26 respectively 1100FTMP FTMP treatmentprotocol protocol treatmentsprotocols treatments (F (Placebo 11 450 50 4,5 900 00 9,0 (%SHR (PLM 0.00 015 0.15 15 45 4, 90 9, 0.0 01 0.1 0.

RESUMEN Objetivo: Identificar la prevalencia de errores que causaron eventos supuestamente atribuibles a la vacunación o inmunización. Método: Revisión sistemática de la literatura con metaanálisis realizada en las bases de datos Medline, Cochrane Library, Cinahl, Web of Science, Lilacs, Scopus; Embase; Open Grey; Google Scholar; y Grey Lit; con estudios que presentaran la prevalencia de errores de inmunización que causaron eventos o que aportaran datos que permitieran calcular este indicador. Resultados: Se evaluaron 11 artículos publicados entre 2010 y 2021, indicando una prevalencia de 0,044 errores por cada 10.000 dosis administradas (n=762; IC95%: 0,026 - 0,075; I2 = 99%, p < 0,01). La prevalencia fue mayor en niños menores de 5 años (0,334 / 10.000 dosis; n=14). Los eventos predominantes fueron fiebre, dolor local, edema y enrojecimiento. Conclusión: Se identificó una baja prevalencia de eventos causantes de errores. Sin embargo, los eventos supuestamente atribuibles a la vacunación o inmunización pueden contribuir a la indecisión sobre la vacunación y, en consecuencia, repercutir en la cobertura vacunal. Objetivo Método Medline Library Cinahl Science Lilacs Scopus Embase Scholar Lit indicador Resultados 1 201 2021 0044 0 044 0,04 10000 10 000 10.00 n=762 n762 n 762 (n=762 IC95% IC95 IC 0026 026 0,02 0,075 0075 075 I 99 99% 0,01. 001 0,01 . 01 0,01) 0,334 0334 334 (0,33 n=14. n14 n=14 14 n=14) fiebre local enrojecimiento Conclusión embargo consecuencia vacunal 20 202 004 04 0,0 1000 00 10.0 n=76 n76 76 (n=76 IC9 002 02 0,07 007 07 9 0,33 033 33 (0,3 n1 n=1 2 0, 100 10. n=7 n7 7 (n=7 0,3 03 3 (0, n= (n= (0 (n (

ABSTRACT Objective: To identify the prevalence of errors that caused events supposedly attributable to vaccination or immunization. Method: Systematic literature review with meta-analysis carried out on the Medline, Cochrane Library, Cinahl, Web of Science, Lilacs, Scopus; Embase; Open Grey; Google Scholar; and Grey Lit databases; with studies that presented the prevalence of immunization errors that caused events or that provided data that allowed this indicator to be calculated. Results: We evaluated 11 articles published between 2010 and 2021, indicating a prevalence of 0.044 errors per 10,000 doses administered (n=762; CI95%: 0.026 - 0.075; I2 = 99%, p < 0.01). The prevalence was higher in children under 5 (0.334 / 10,000 doses; n=14). The predominant events were fever, local pain, edema and redness. Conclusion: A low prevalence of errors causing events was identified. However, events supposedly attributable to vaccination or immunization can contribute to vaccine hesitancy and, consequently, have an impact on vaccination coverage. Objective Method metaanalysis meta analysis Medline Library Cinahl Science Lilacs Scopus Embase Scholar databases calculated Results 1 201 2021 0044 0 044 0.04 10000 10 000 10,00 n=762 n762 n 762 (n=762 CI95% CI95 CI 0026 026 0.02 0.075 0075 075 I 99 99% 0.01. 001 0.01 . 01 0.01) 0.334 0334 334 (0.33 n=14. n14 n=14 14 n=14) fever pain redness Conclusion identified However consequently coverage 20 202 004 04 0.0 1000 00 10,0 n=76 n76 76 (n=76 CI9 002 02 0.07 007 07 9 0.33 033 33 (0.3 n1 n=1 2 0. 100 10, n=7 n7 7 (n=7 0.3 03 3 (0. n= (n= (0 (n (

RESUMO Objetivo: Identificar a prevalência de erros que causaram eventos supostamente atribuíveis à vacinação ou imunização. Método: Revisão sistemática da literatura com metanálise realizada nas bases Medline, Cochrane Library, Cinahl, Web of Science, Lilacs, Scopus; Embase; Open Grey; Google Scholar; e Grey Lit; com estudos que apresentassem prevalência de erros de imunização que causaram eventos ou que disponibilizassem dados que permitissem o cálculo deste indicador. Resultados: Avaliou-se 11 artigos publicados entre 2010 e 2021, apontando prevalência de 0,044 erros por 10.000 doses administradas (n=762; IC95%: 0,026 - 0,075; I2= 99%, p < 0,01). A prevalência foi maior em crianças menores de 5 anos (0,334 / 10.000 doses; n=14). Quanto aos eventos, predominou-se: febre, dor local, edema, rubor. Conclusão: Identificou-se uma prevalência baixa de erros que causaram eventos. Entretanto, os eventos supostamente atribuíveis à vacinação ou imunização podem contribuir para a hesitação vacinal e, consequentemente, impactar nas coberturas vacinais. Objetivo Método Medline Library Cinahl Science Lilacs Scopus Embase Scholar Lit indicador Resultados Avaliouse Avaliou se 1 201 2021 0044 0 044 0,04 10000 10 000 10.00 n=762 n762 n 762 (n=762 IC95% IC95 IC 0026 026 0,02 0,075 0075 075 I2 I 99 99% 0,01. 001 0,01 . 01 0,01) 0,334 0334 334 (0,33 n=14. n14 n=14 14 n=14) predominouse predominou predominou-se febre local edema rubor Conclusão Identificouse Identificou Entretanto consequentemente vacinais 20 202 004 04 0,0 1000 00 10.0 n=76 n76 76 (n=76 IC9 002 02 0,07 007 07 9 0,33 033 33 (0,3 n1 n=1 2 0, 100 10. n=7 n7 7 (n=7 0,3 03 3 (0, n= (n= (0 (n (

Resumo Esta pesquisa tem por objetivo verificar o efeito da cobertura da mídia no gerenciamento de resultados das companhias abertas brasileiras. Utilizou-se uma amostra de 284 empresas brasileiras não financeiras, listadas na B3 com dados trimestrais no período de 2011-2022. A cobertura da mídia foi mensurada pelo logaritmo natural do número de notícias publicadas sobre as firmas, e, para o gerenciamento de resultados, empregou-se um modelo de detecção por meio de accruals (Collins et al., 2017), estimados mediante painel desbalanceado em GMM 2SLS. Os resultados demonstram uma associação negativa entre a cobertura da mídia e o gerenciamento de resultados, indicando que os gestores, mediante a visibilidade midiática, tendem a gerenciar menos os resultados para evitar desdobramentos negativos sobre o desvio do valor real do lucro. A pesquisa revela que a mídia brasileira atua como agente externo de governança ao induzir, via monitoramento das ações gerenciais, a melhoria da informação contábil. Ante a relevância do papel exercido pela mídia, sobretudo pela rápida disseminação da informação, os resultados demonstram que a cobertura midiática contribui na redução de ruídos oriundos do gerenciamento de resultados. Desdobramentos dessa constatação podem impactar gestores e o mercado de capitais por explicitarem que a mídia é um agente que interfere, ainda que indiretamente, nas ações corporativas. Tem-se, portanto, que a mídia influencia diferentes organizações, com efeitos em práticas gerenciais que buscam melhorar a transparência. O estudo busca preencher uma lacuna quanto ao efeito da cobertura da mídia brasileira no gerenciamento de resultados, lançando luz sobre a mídia como elemento externo de governança corporativa que contribui para um ambiente de melhor informação de natureza contábil. Utilizouse Utilizou se 28 financeiras B 20112022. 20112022 2011 2022. 2022 2011-2022 firmas empregouse empregou Collins al al. 2017, 2017 , 2017) 2SLS SLS lucro induzir contábil interfere indiretamente corporativas Temse, Temse Tem se, Tem-se portanto organizações transparência 2 2011202 201 202 2011-202 201120 20 2011-20 20112 2011-2 2011-

ABSTRACT This study aims to verify the effect of media coverage on the earnings management of Brazilian listed companies. A sample of 284 Brazilian non-financial companies listed on the B3 was used, with quarterly data for the period 2011-2022. Media coverage was measured by the natural logarithm of the number of news stories released about the firms, and for earnings management, a detection model with accruals was used (Collins et al., 2017), estimated using an unbalanced panel in GMM 2SLS. The results show a negative association between media coverage and earnings management, indicating that managers tend to manage earnings less in the presence of media visibility, in order to avoid negative effects on the deviation from the real value of earnings. The research reveals that the Brazilian media acts as an external agent of governance, inducing the improvement of accounting information by monitoring management actions. Given the importance of the role played by the media, especially through the rapid dissemination of information, the results show that media coverage contributes to reducing the noise generated by earnings management. This finding could have implications for managers and the capital market, as it shows that the media is an agent that interferes, albeit indirectly, with corporate actions. Therefore, the media influences various organizations, with implications for management practices that seek to improve transparency. The study seeks to fill a gap regarding the effect of Brazilian media coverage on earnings management, shedding light on the media as an external element of corporate governance that contributes to an environment of better accounting information. 28 nonfinancial non financial B 20112022. 20112022 2011 2022. 2022 2011-2022 firms Collins al al. 2017, 2017 , 2017) 2SLS SLS visibility actions market interferes indirectly Therefore organizations transparency 2 2011202 201 202 2011-202 201120 20 2011-20 20112 2011-2 2011-